Cell Death & Disease

Article	Citations
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis	355
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model	326
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7	306
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α	300
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons	291
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis	272
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma	214
Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma	209
Elaiophylin reduces body weight and lowers glucose levels in obese mice by activating AMPK	201
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC	200
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3	194
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats	173
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation	169
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12	163
IL-17A injury to retinal ganglion cells is mediated by retinal Müller cells in diabetic retinopathy	158
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation	156
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis	156
Correction: NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation	148
Leveraging glycosylation for early detection and therapeutic target discovery in pancreatic cancer	146
Correction: Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis	142
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells	142
Metalloproteinase 1 downregulation in neurofibromatosis 1: Therapeutic potential of antimalarial hydroxychloroquine and chloroquine	140
A carbazole compound, 9-ethyl-9H-carbazole-3-carbaldehyde, plays an antitumor function through reactivation of the p53 pathway in human melanoma cells	139
Resistance of bone marrow stroma to genotoxic preconditioning is determined by p53	139
KDM1A epigenetically enhances RAD51 expression to suppress the STING-associated anti-tumor immunity in esophageal squamous cell carcinoma	138

Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence	137
Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α	135
Knockdown of Porf-2 restores visual function after optic nerve crush injury	133
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication	132
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea	132
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling	131
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker	130
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation	128
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation	128
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function	125
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment	125
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila	125
p63, a key regulator of Ago2, links to the microRNA-144 cluster	124
METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle	124
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way	120
Defective hematopoietic differentiation of immune aplastic anemia patient-derived iPSCs	119
Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist	116
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor	115
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation	115
A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling	114
CAR-T therapy dilemma and innovative design strategies for next generation	113
IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer	113
SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction	110
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation	109
Underlying mechanisms of glucocorticoid-induced β-cell death and dysfunction: a new role for glycogen synthase kinase 3	109
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD	108
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects	107
UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963	105
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression	103
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma	102
GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway	102
FAK mediates LPS-induced inflammatory lung injury through interacting TAK1 and activating TAK1-NFκB pathway	101
Pharmacological inhibition of Ref-1 enhances the therapeutic sensitivity of papillary thyroid carcinoma to vemurafenib	101
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review	100
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1	100
MESH1 knockdown triggers proliferation arrest through TAZ repression	100
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma	98
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer	97
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin–ferroptosis axis	96
Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhi	96
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression	95
TRAIL protects the immature lung from hyperoxic injury	94
NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma	91
The tyrosine-kinase inhibitor Nintedanib ameliorates autosomal-dominant polycystic kidney disease	91
Apatinib inhibits glioma cell malignancy in patient-derived orthotopic xenograft mouse model by targeting thrombospondin 1/myosin heavy chain 9 axis	90
GPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis	90
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling	89
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis	89
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop	89
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation	87

PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer	86
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3	86
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury	86
Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia	85
An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis	85
RNF115/BCA2 deficiency alleviated acute liver injury in mice by promoting autophagy and inhibiting inflammatory response	83
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation	83
Glucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival	82
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis	82
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy	82
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway	82
Endothelial ETS1 inhibition exacerbate blood–brain barrier dysfunction in multiple sclerosis through inducing endothelial-to-mesenchymal transition	81
Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK2	80
The regulation, function, and role of lipophagy, a form of selective autophagy, in metabolic disorders	80
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice	80
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway	80
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition	79
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma	79
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma	79
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1	79
Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity	78
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway	78
In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy	78
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma	78
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer	77
Identification of multiple organ metastasis-associated hub mRNA/miRNA signatures in non-small cell lung cancer	76
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6	75
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity	74
Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders	74
BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury	74
PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway	74
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications	73
m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization	72
Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish	71
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis	71
JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis	70
ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells	70
SOX4-BMI1 axis promotes non-small cell lung cancer progression and facilitates angiogenesis by suppressing ZNF24	70
CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling	69
Circular RNA hsa_circ_0000277 sequesters miR-4766-5p to upregulate LAMA1 and promote esophageal carcinoma progression	69
Regulatory T cells in skeletal muscle repair and regeneration: recent insights	69
Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model	69
CircNEIL3 mediates pyroptosis to influence lung adenocarcinoma radiotherapy by upregulating PIF1 through miR-1184 inhibition	69
SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis	69
MIR22HG inhibits breast cancer progression by stabilizing LATS2 tumor suppressor	68
Suppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis	68
LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy	68
Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy	67
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function	67
Metabolic gatekeepers: harnessing tumor-derived metabolites to optimize T cell-based immunotherapy efficacy in the tumor microenvironment	67
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia	67
Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors	66
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway	66
SAP130 released by damaged tubule drives necroinflammation via miRNA-219c/Mincle signaling in acute kidney injury	66
Trim21-mediated CCT2 ubiquitination suppresses malignant progression and promotes CD4+T cell activation in breast cancer	66
Glycolysis-related lncRNA TMEM105 upregulates LDHA to facilitate breast cancer liver metastasis via sponging miR-1208	65
MicroRNA miR-1275 coordinately regulates AEA/LPA signals via targeting FAAH in lipid metabolism reprogramming of gastric cancer	65
Opposing roles for GSK3β and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in Huntington’s disease	65
Androgen-targeted hsa_circ_0085121 encodes a novel protein and improves the development of prostate cancer through facilitating the activity of PI3K/Akt/mTOR pathway and enhancing AR-V7 alternative sp	64
TNFAIP2 promotes HIF1α transcription and breast cancer angiogenesis by activating the Rac1-ERK-AP1 signaling axis	64
A positive feedback loop of lncRNA-RMRP/ZNRF3 axis and Wnt/β-catenin signaling regulates the progression and temozolomide resistance in glioma	64
Chemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells	64
DDX5 deficiency drives non-canonical NF-κB activation and NRF2 expression, influencing sorafenib response and hepatocellular carcinoma progression	63
Tim-3+ decidual Mφs induced Th2 and Treg bias in decidual CD4+T cells and promoted pregnancy maintenance via CD132	63
Nitroglycerin: a comprehensive review in cancer therapy	63
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis	62
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease	62
Stanniocalcin 1 promotes lung metastasis of breast cancer by enhancing EGFR–ERK–S100A4 signaling	62
Downregulated liver-elevated long intergenic noncoding RNA (LINC02428) is a tumor suppressor that blocks KDM5B/IGF2BP1 positive feedback loop in hepatocellular carcinoma	62
Correction: MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET–SOCS1–MMP9 signaling axis	62
High dose androgen suppresses natural killer cytotoxicity of castration-resistant prostate cancer cells via altering AR/circFKBP5/miRNA-513a-5p/PD-L1 signals	62
An integrative transcriptome study reveals Ddit4/Redd1 as a key regulator of cancer cachexia in rodent models	62
Germline specific genes increase DNA double-strand break repair and radioresistance in lung adenocarcinoma cells	61
Correction: FANCI plays an essential role in spermatogenesis and regulates meiotic histone methylation	61
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer	61
TAB182 aggravates progression of esophageal squamous cell carcinoma by enhancing β-catenin nuclear translocation through FHL2 dependent manner	61
Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies	61
Nuclear pore protein POM121 regulates subcellular localization and transcriptional activity of PPARγ	61
Retraction Note: Long noncoding RNA LINC01234 promotes serine hydroxymethyltransferase 2 expression and proliferation by competitively binding miR-642a-5p in colon cancer	60
MLK4 regulates DNA damage response and promotes triple-negative breast cancer chemoresistance	60

Wet-dry-wet drug screen leads to the synthesis of TS1, a novel compound reversing lung fibrosis through inhibition of myofibroblast differentiation	60
Retraction Note: Exosome-transmitted miR-567 reverses trastuzumab resistance by inhibiting ATG5 in breast cancer	60
Retraction Note: Dual roles of miR-374a by modulated c-Jun respectively targets CCND1-inducing PI3K/AKT signal and PTEN-suppressing Wnt/β-catenin signaling in non-small-cell lung cancer	60
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss	60
Correction to: Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	60
Nerve growth factor promotes lysyl oxidase-dependent chondrosarcoma cell metastasis by suppressing miR-149-5p synthesis	60
p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-1	59
Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia	59
S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis	59
LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2	59
Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation	59
TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4	59
Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy	58
Selective degradation of AR-V7 to overcome castration resistance of prostate cancer	57
Novel roles of luteinizing hormone (LH) in tissue regeneration-associated functions in endometrial stem cells	57
The feedback loop between MTA1 and MTA3/TRIM21 modulates stemness of breast cancer in response to estrogen	56
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis	56
Ascitic fluid shear stress in concert with hepatocyte growth factor drive stemness and chemoresistance of ovarian cancer cells via the c-Met-PI3K/Akt-miR-199a-3p signaling pathway	55
The role of vitamin K and its antagonist in the process of ferroptosis-damaged RPE-mediated CNV	55
ZFP36L2 regulates myocardial ischemia/reperfusion injury and attenuates mitochondrial fusion and fission by LncRNA PVT1	55
Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction	55
BH3-only protein expression determines hepatocellular carcinoma response to sorafenib-based treatment	55
YAP1 facilitates the pathogenesis of psoriasis via modulating keratinocyte proliferation and inflammation	55
STING dependent BAX-IRF3 signaling results in apoptosis during late-stage Coxiella burnetii infection	55
Correction to: Deubiquitylase OTUD6B stabilizes the mutated pVHL and suppresses cell migration in clear cell renal cell carcinoma	55
Long non-coding RNA Xist regulates oocyte loss via suppressing miR-23b-3p/miR-29a-3p maturation and upregulating STX17 in perinatal mouse ovaries	55
Transglutaminase 2 associated with PI3K and PTEN in a membrane-bound signalosome platform blunts cell death	54
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice	54
Therapeutic targeting of both dihydroorotate dehydrogenase and nucleoside transport in MYCN-amplified neuroblastoma	54
Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells	54
RIPK3 promoter hypermethylation in hepatocytes protects from bile acid-induced inflammation and necroptosis	54
Circulating miR-184 is a potential predictive biomarker of cardiac damage in Anderson–Fabry disease	53
BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy	53
NAT10 mediates TLR2 to promote podocyte senescence in adriamycin-induced nephropathy	53
Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion	53
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer	53
GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy	53
FANCI plays an essential role in spermatogenesis and regulates meiotic histone methylation	53
Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development	53
Card9 protects sepsis by regulating Ripk2-mediated activation of NLRP3 inflammasome in macrophages	53
A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia	53
β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4	52
MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10	52
SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin	52
Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect	52
Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry	52
Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans	52
OGA is associated with deglycosylation of NONO and the KU complex during DNA damage repair	52
Exosomes derived from mesenchymal stem cells in diabetes and diabetic complications	51
Exosomal circTGFBR2 promotes hepatocellular carcinoma progression via enhancing ATG5 mediated protective autophagy	51
TRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation	51
Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy	51
Systemic mechanisms of necrotic cell debris clearance	51
Downregulation of TPX2 impairs the antitumor activity of CD8+ T cells in hepatocellular carcinoma	51
Retraction Note to: Expansion of monocytic myeloid-derived suppressor cells ameliorated intestinal inflammatory response by radiation through SOCS3 expression	51
O-GlcNAcylation inhibition redirects the response of colon cancer cells to chemotherapy from senescence to apoptosis	51
Hepatocyte DDX3X protects against drug-induced acute liver injury via controlling stress granule formation and oxidative stress	50
DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism	50
Angiotensin II related glial cell activation and necroptosis of retinal ganglion cells after systemic hypotension in glaucoma	50
Deficiency of PPP6C protects TNF-induced necroptosis through activation of TAK1	50
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer	50
Generation of functional neurons from adult human mucosal olfactory ensheathing glia by direct lineage conversion	49
Cerebral endothelial cell-derived extracellular vesicles regulate microglial polarization and promote autophagy via delivery of miR-672-5p	49
AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer	49
The YTHDC1 reader protein recognizes and regulates the lncRNA MEG3 following its METTL3-mediated m6A methylation: a novel mechanism early during radiation-induced liver injury	49
Transcriptome reprogramming of Epstein-Barr virus infected epithelial and B cells reveals distinct host-virus interaction profiles	49
ETS-1-activated LINC01016 over-expression promotes tumor progression via suppression of RFFL-mediated DHX9 ubiquitination degradation in breast cancers	49
CircLIFR suppresses hepatocellular carcinoma progression by sponging miR-624-5p and inactivating the GSK-3β/β-catenin signaling pathway	49
nNOS in Erbb4-positive neurons regulates GABAergic transmission in mouse hippocampus	48
Advances in research on immunocyte iron metabolism, ferroptosis, and their regulatory roles in autoimmune and autoinflammatory diseases	48
EGFL7 drives the evolution of resistance to EGFR inhibitors in lung cancer by activating NOTCH signaling	48
HMGA2 alleviates ferroptosis by promoting GPX4 expression in pancreatic cancer cells	48
c-FLIP regulates autophagy by interacting with Beclin-1 and influencing its stability	48
FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion	48
ALCAP2 inhibits lung adenocarcinoma cell proliferation, migration and invasion via the ubiquitination of β-catenin by upregulating the E3 ligase NEDD4L	48
Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction	48
The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2	48
TGF-β-induced PLEK2 promotes metastasis and chemoresistance in oesophageal squamous cell carcinoma by regulating LCN2	48
Potential role of senescent macrophages in radiation-induced pulmonary fibrosis	48
Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer	47
The duality of CXCR3 in glioblastoma: unveiling autocrine and paracrine mechanisms for novel therapeutic approaches	47
Exosomal circRNA BTG2 derived from RBP-J overexpressed-macrophages inhibits glioma progression via miR-25-3p/PTEN	47
Endothelial cell-derived RSPO3 activates Gαi1/3-Erk signaling and protects neurons from ischemia/reperfusion injury	47
Neddylation-mediated degradation of hnRNPA2B1 contributes to hypertriglyceridemia pancreatitis	47
PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation	47
LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1	47
PSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ	46
The regulations of telomerase reverse transcriptase (TERT) in cancer	46
CAF-derived exosomal WEE2-AS1 facilitates colorectal cancer progression via promoting degradation of MOB1A to inhibit the Hippo pathway	46
PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation	46
PRL-mediated STAT5B/ARRB2 pathway promotes the progression of prostate cancer through the activation of MAPK signaling	46
Suppression of lncRNA NLRP3 inhibits NLRP3-triggered inflammatory responses in early acute lung injury	46
Simvastatin rescues memory and granule cell maturation through the Wnt/β-catenin signaling pathway in a mouse model of Alzheimer’s disease	46
Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor	46
TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis	46