OOIR: Observatory of International Research

Papers

(The median citation count of Therapeutic Advances in Chronic Disease is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Latest update on the use of recombinant growth factors for periodontal regeneration: existing evidence and clinical applications	159
Morphological alterations of the hypothalamus in idiopathic intracranial hypertension	31
Effectiveness of using calligraphic activity to treat people with schizophrenia: a randomized controlled trial in Southern Taiwan	30
Non-inferiority of 1 month versus longer dual antiplatelet therapy in patients undergoing PCI with drug-eluting stents: a systematic review and meta-analysis of randomized clinical trials	28
Colon capsule retention in a patient with large bowel stenosis due to diverticulosis – a case report	22
What is the role of Von Willebrand factor in chronic hepatitis B virus infection to hepatocellular carcinoma: a review article	21
Association between sensitivity to thyroid hormone indices and osteoporosis in euthyroid patients with type 2 diabetes mellitus	21
Potential roles of gut microbiota and microbial metabolites in chronic inflammatory pain and the mechanisms of therapy drugs	21
Periodontal inflammation is associated with increased circulating levels of endothelial progenitor cells: a retrospective cohort study in a high vascular risk population	20
First-line therapeutic strategy for patients with advanced non–small cell lung cancer with Leu858Arg epidermal growth factor receptor mutations: a Bayesian network meta-analysis	19
Prevalence of major non-communicable diseases and their associated risk factors in Afghanistan: a systematic review and meta-analysis	19
Periprocedural, short-term, and long-term outcomes following transcatheter tricuspid valve repair: a systemic review and meta-analysis	18
Effect of sodium-glucose cotransporter-2 (SGLT2) inhibitors on serum urate levels in patients with and without diabetes: a systematic review and meta-regression of 43 randomized controlled trials	18
Real-world non-interventional post-authorization safety study of long-term use of burosumab in children and adolescents with X-linked hypophosphatemia: first interim analysis	16
Association between galectin-3 and hepatosteatosis in a community-based cross-sectional study	15
Preoperative malnutrition as an independent risk factor for the postoperative mortality in elderly Chinese individuals undergoing hip surgery: a single-center observational study	15
Comparisons of psychological distress and self-stigma among three types of substance use disorders receiving treatment-as-usual approaches: real-world data from a 9-month longitudinal study	15
Short- and long-term effects of whole-body photobiomodulation on pain, functionality, tissue quality, central sensitisation and psychological factors in a population suffering from fibromyalgia: proto	15
Associations between age-related hearing loss, cognitive decline, and depression in Chinese centenarians and oldest-old adults	14
Remission and relapses of myasthenia gravis on long-term tacrolimus: a retrospective cross-sectional study of a Chinese cohort	14
Inheritance and innovation of the diagnosis of peripheral pulmonary lesions	13
Associations between bone mineral density and coronary artery calcification: a systematic review and meta-analysis	12
Electronic patient-reported outcomes in clinical kidney practice (ePRO Kidney): a process evaluation of educational support for clinicians	11
Establishment of a preliminary FRAX®-based intervention threshold for rheumatoid arthritis–associated fragility fracture: a 3-year longitudinal, observational, cohort study	11
Complementary and alternative medicine for long COVID: a systematic review of randomized controlled trials	11

Real-world safety and effectiveness of secukinumab in adult patients with moderate to severe plaque psoriasis: results from postmarketing surveillance in Korea	11
Two-year real-world outcome data from a single tertiary centre shows reduced ustekinumab persistence in a non-bio-naïve Crohn’s disease cohort with penetrating disease, -ostomies and sarcopenia	11
Efficacy and safety of bisphosphonates on childhood osteoporosis secondary to chronic illness or its treatment: a meta-analysis	10
Clinical characteristics of hospitalized patients with metabolic-associated fatty liver disease–related liver cancer: data from a single center, 2010–2019	10
Emerging roles of macrophages in heart failure and associated treatment approaches	10
Tenofovir is superior to entecavir in reducing HCC for patients with HBV-related compensated cirrhosis at high HCC risk scores	10
Comparison of different medical treatments for primary hyperaldosteronism: a systematic review and network meta-analysis	10
Air pollution and mortality in patients with chronic obstructive pulmonary disease: a cohort study in South Korea	10
Bispecific antibody treatment of multiple myeloma: latest updates from the 2022 ASH annual meeting	9
Hematological parameters and early-onset coronary artery disease: a retrospective case–control study based on 3366 participants	9
Is Helicobacter pylori infection associated with pancreatic cancer? A systematic review and meta-analysis of observational studies	9
Hispanic adults with type 2 diabetes mellitus using lipid-lowering agents have better periodontal health than non-users	9
Corrigendum to air pollution and mortality in patients with chronic obstructive pulmonary disease: a cohort study in South Korea	9
Effect of semaglutide and liraglutide in individuals with obesity or overweight without diabetes: a systematic review	8
Lifetime risk, life expectancy, loss-of-life expectancy, and lifetime healthcare expenditures for psoriasis in Taiwan: a nationwide cohort followed from 2000 to 2017	8
Fecal microbiota transplantation treatment for type 1 diabetes mellitus with malnutrition: a case report	8
Eosinophilia attention, diagnosis, treatment, and awareness in physicians: a cross-sectional survey	8
Willingness to start insulin therapy among insulin-naïve persons with type 2 diabetes mellitus at Gulu Regional Referral Hospital, Gulu City, Uganda	8
Sarcopenia and frailty combined increases the risk of mortality in patients with decompensated cirrhosis	8
Clinical scenarios-based guide for tofacitinib in rheumatoid arthritis	8
Is Chinese herbal formula (nourishing Yin therapy) effective and well tolerated as an adjunct medication to hydroxychloroquine in the treatment of primary Sjögren’s syndrome? A meta-analysis of random	8
Autoimmune colitis and neutropenia in adjuvant anti-PD-1 therapy for malignant melanoma: efficacy of Vedolizumab, a case report	8
Machine learning approaches for the mortality risk assessment of patients undergoing hemodialysis	8
The efficacy of telemedicine for pain management in patients with cancer: a systematic review and meta-analysis	8
Anatomical and functional remodeling of left ventricle in patients with primary aldosteronism and concomitant albuminuria	8
Sailing the ship of life: scurvy and autoimmunity . . .	7
Potential application of Klotho as a prognostic biomarker for patients with diabetic kidney disease: a meta-analysis of clinical studies	7
Transcranial alternating current stimulation and its effects on cognition and the treatment of psychiatric disorders: a systematic review and meta-analysis	7
Risk factors of significant relapse and appropriate maintenance therapy strategy in SLE-associated immune thrombocytopenia	7
Application of fucoidan as treatment for cardiovascular and cerebrovascular diseases	7
Characteristics of myeloproliferative neoplasm-associated portal hypertension and endoscopic management of variceal bleeding	7
Relaxation-weighted ²³Na magnetic resonance imaging maps regional patterns of abnormal sodium concentrations in amyotrophic lateral sclerosis	7
Diagnostic value of reflux episodes in gastroesophageal reflux-induced chronic cough: a novel predictive indicator	7
The optimal percutaneous coronary intervention strategy for patients with ST-segment elevation myocardial infarction and multivessel disease: a pairwise and network meta-analysis	6
A primer on common supplements and dietary measures used by patients with inflammatory bowel disease	6
Advancements in prevention and intervention of sensorineural hearing loss	6
Revascularization or medical therapy for stable coronary artery disease patients with different degrees of ischemia: a systematic review and meta-analysis of the role of myocardial perfusion	6
Optimal treatment targets for lupus nephritis using per-protocol repeat kidney biopsy findings at 2 years and clinical data up to 5 years: a single-center observational study	6
Chronotherapy of cardiovascular pathologies: a hopeful strategy	6
Metformin use is associated with low risk of case fatality and disability rates in first-ever stroke patients with type 2 diabetes	6
Single-pill fixed-dose drug combinations to reduce blood pressure: the right pill for the right patient	6
Resective surgery for patients with frontal lobe diffuse low-grade glioma-related epilepsy: predictors of seizure outcomes	6
The interaction and pathogenesis between cognitive impairment and common cardiovascular diseases in the elderly	5
Therapeutic decisions in a cohort of patients with idiopathic pulmonary fibrosis: a multicenter, prospective survey from Poland	5
Association between non-alcoholic fatty liver disease and risk of incident heart failure: a meta-analysis of observational studies	5
Aortic arch calcification increases major adverse cardiac event risk, modifiable by echocardiographic left ventricular hypertrophy, in end-stage kidney disease patients	5
Spleen stiffness determined by spleen-dedicated device accurately predicted esophageal varices in cirrhosis patients	5
Impact of cytomegalovirus on outcomes in acute severe ulcerative colitis: a retrospective observational study	5
Development of the ESEx index: a tool for predicting risk of recurrent severe COPD exacerbations	5
The Asia Pacific Pediatric Association (APPA) position statement on the MAFLD definition of fatty liver disease	5

The use of complementary and alternative medicine for the treatment of gastrointestinal symptoms in Long COVID: a systematic review	5
Strongyloidiasis: what every gastroenterologist needs to know	5
Characterization of serum polyunsaturated fatty acid profile in patients with inflammatory bowel disease	5
Comparison of rivaroxaban-based dual antithrombotic and antiplatelet therapies for symptomatic patients with lower-extremity peripheral artery disease post-revascularization: a retrospective cohort st	5
Can chronic kidney disease staging early predict outcome of large-artery ischemic stroke with impaired renal function?	5
Take vedolizumab home: transition from intravenous to subcutaneous treatment	5
Relationship between vascular access and angulation of vena cava filter at placement and retrieval: a multicenter retrospective cohort study	5
Deep learning-based fundus image analysis for cardiovascular disease: a review	5
Association of Barrett’s esophagus with Helicobacter pylori infection: a meta-analysis	5
A randomized, controlled trial on fenofibrate in primary biliary cholangitis patients with incomplete response to ursodeoxycholic acid	5
The need for a strategic therapeutic approach: multiple sclerosis in check	5
Chemotherapy for patients with advanced lung cancer with interstitial lung disease: a prospective observational study	5
Interdisciplinary approach to patients with psoriatic arthritis: a prospective, single-center cohort study	4
Clinical and imaging findings in enteropathic spondyloarthritis with special emphasize in diagnostic delay: a cross-sectional study	4
High-normal free thyroxine level is related with decreased bone mineral density in nonobese male patients with type 2 diabetes over 50 years old	4
Cyclosporin A as an adjunct may enhance the therapeutic effect of interferon alpha-2a in patients with refractory Behcet’s uveitis: a retrospective cohort study	4
Blood pressure measurement in the elderly with atrial fibrillation: an observational study comparing different noninvasive sphygmomanometers	4
Effect of short-term cardiac function changes after cardiac resynchronization therapy on long-term prognosis in heart failure patients with and without diabetes	4
The impact of elexacaftor/tezacaftor/ivacaftor on cystic fibrosis health-related quality of life and decision-making about daily treatment regimens: a mixed methods exploratory study	4
‘When Cryptococcus strikes and lupus is found’: a unique covert unveiling of systemic lupus erythematosus presenting as subacute meningitis	4
Characteristics and outcomes of patients with psoriasis treated with apremilast in the real-world in Austria – results the APPRECIATE study	4
Hair repigmentation and regrowth in a dupilumab-treated paediatric patient with alopecia areata and atopic dermatitis: a case report	4
Third-line treatment patterns and clinical outcomes for metastatic colorectal cancer: a retrospective real-world study	4
Effects of non-invasive brain stimulation in multiple sclerosis: systematic review and meta-analysis	4
Ultrasound therapy for pain reduction in musculoskeletal disorders: a systematic review and meta-analysis	4
An analysis report on the application of immune checkpoint inhibitors after liver transplantation	4
Deep and unbiased proteomics, pathway enrichment analysis, and protein–protein interaction of biomarker signatures in migraine	4
Afterload-related cardiac performance is a powerful hemodynamic predictor of mortality in patients with chronic heart failure	4
Lack of awareness and ethnic polarity is a major cause of metabolic associated fatty liver disease in high-risk diabetes population in South London	4
Fractional nitric oxide measurement in exhaled air (FeNO): perspectives in the management of respiratory diseases	4
Photodynamic therapy of cervical cancer: a scoping review on the efficacy of various molecules	4
The totality of evidence approach in the development of AVT02 (adalimumab), a biosimilar to Humira	3
Association between age, sex and cervical and upper cervical rotation tests. Descriptive and correlational study in healthy volunteers	3
Brain functional and structural changes in diabetic children. How can intellectual development be optimized in type 1 diabetes?	3
Association between thyroid hormones and skeletal muscle and bone in euthyroid type 2 diabetes patients	3
Association of NAFLD with cardiovascular disease and all-cause mortality: a large-scale prospective cohort study based on UK Biobank	3
Long-chain omega-3 polyunsaturated fatty acids and the risk of heart failure	3
Efficacy and potential predictors of vagus nerve stimulation therapy in refractory postencephalitic epilepsy	3
Author response to comment on: Hematological parameters and early-onset coronary artery disease: a retrospective case-control study based on 3366 participants	3
Trends in mortality from infection among patients with hematologic malignancies: differences according to hematologic malignancy subtype	3
Impact of local drug delivery and natural agents as new target strategies against periodontitis: new challenges for personalized therapeutic approach	3
Quantitative evaluation of risk factors for low back pain in young patients using synthetic magnetic resonance imaging and proton density fat fraction analyses	3
Improving diagnosis of primary aldosteronism through education: a modified Delphi study to identify key learning points	3
State of the art: non-invasive electrical stimulation for the treatment of chronic tinnitus	3
A new dual function dorsal root ganglion stimulation in pain management: a technical note and case report	3
Nonalcoholic fatty liver disease and health outcomes: An umbrella review of systematic reviews and meta-analyses	3
Flare management in atopic dermatitis: from definition to treatment	3
Post-authorisation safety study of burosumab use in paediatric, adolescent and adult patients with X-linked hypophosphataemia: rationale and description	3
Personalized medicine with drugs targeting the underlying protein defect in cystic fibrosis: is monitoring of treatment response necessary?	3
Causal associations of immunophenotypes with metabolic dysfunction-associated fatty liver disease and mediating pathways: a Mendelian randomization study	3
Prior percutaneous coronary intervention and outcomes in patients after coronary artery bypass grafting: a meta-analysis of 308,284 patients	3
CMS-NET: deep learning algorithm to segment and quantify the ciliary muscle in swept-source optical coherence tomography images	3
Long-term surveillance of liver histological changes in chronic hepatitis C patients completing pegylated interferon-α plus ribavirin therapy: an observational cohort study	3
Association between serum pyridoxal 5′-phosphate levels and all-cause, cardiovascular mortality, and cardiovascular disease in adults: a population-based cohort study	3
Novel homozygous mutation of PNLIP gene in congenital pancreatic lipase deficiency: an extended family study	3
AES-CSFS: an automatic evaluation system for corneal sodium fluorescein staining based on deep learning	3