Therapeutic Advances in Chronic Disease

Article	Citations
Neurological manifestations of long-COVID syndrome: a narrative review	143
Nomenclature and clinical phenotypes of atopic dermatitis	48
A narrative review of current evidence supporting the implementation of electronic patient-reported outcome measures in the management of chronic diseases	33
New perspectives on the treatment of hidradenitis suppurativa	31
Dual inhibition of IL-17A and IL-17F in psoriatic disease	31
MicroRNA-21 from bone marrow mesenchymal stem cell-derived extracellular vesicles targets TET1 to suppress KLF4 and alleviate rheumatoid arthritis	30
The neurological symptoms of COVID-19: a systematic overview of systematic reviews, comparison with other neurological conditions and implications for healthcare services	27
Impact of previous biologic use and body weight on the effectiveness of guselkumab in moderate-to-severe plaque psoriasis: a real-world practice	27
Serum-derived exosomes containing NEAT1 promote the occurrence of rheumatoid arthritis through regulation of miR-144-3p/ROCK2 axis	26
The interaction and pathogenesis between cognitive impairment and common cardiovascular diseases in the elderly	24
Effect of sodium-glucose cotransporter-2 (SGLT2) inhibitors on serum urate levels in patients with and without diabetes: a systematic review and meta-regression of 43 randomized controlled trials	23
Mesenchymal stem cell-based treatment in autoimmune liver diseases: underlying roles, advantages and challenges	22
Melatonin restores osteoporosis-impaired osteogenic potential of bone marrow mesenchymal stem cells and alleviates bone loss through the HGF/PTEN/Wnt/β-catenin axis	22
Effects of non-invasive brain stimulation in multiple sclerosis: systematic review and meta-analysis	21
Steatosis grading consistency between controlled attenuation parameter and MRI-PDFF in monitoring metabolic associated fatty liver disease	21
Non-alcoholic fatty liver disease is associated with increased risk of chronic kidney disease	21
The association between NAFLD and risk of chronic kidney disease: a cross-sectional study	21
The need for a strategic therapeutic approach: multiple sclerosis in check	20
Adrenocortical carcinoma: current state of the art, ongoing controversies, and future directions in diagnosis and treatment	20
Characteristics and outcomes of patients with chronic thromboembolic pulmonary hypertension in the era of modern therapeutic approaches: data from the Polish multicenter registry (BNP-PL)	18
Relationship between sarcopenia/myosteatosis and frailty in hospitalized patients with cirrhosis: a sex-stratified analysis	18
Long-chain omega-3 polyunsaturated fatty acids and the risk of heart failure	17
Flare management in atopic dermatitis: from definition to treatment	17
Feature selection from magnetic resonance imaging data in ALS: a systematic review	17
Deep learning-based classification of infectious keratitis on slit-lamp images	16

Effect of semaglutide and liraglutide in individuals with obesity or overweight without diabetes: a systematic review	16
Sodium-glucose cotransporter 2 inhibitors and neurological disorders: a scoping review	16
Application of fucoidan as treatment for cardiovascular and cerebrovascular diseases	16
Exploring polypharmacy phenomenon in newly diagnosed relapsing–remitting multiple sclerosis: a cohort ambispective single-centre study	15
Impact of exclusive e-cigarettes and heated tobacco products use on muco-ciliary clearance	15
Single-pill fixed-dose drug combinations to reduce blood pressure: the right pill for the right patient	15
Blood eosinophil count-guided corticosteroid therapy and as a prognostic biomarker of exacerbations of chronic obstructive pulmonary disease: a systematic review and meta-analysis	15
Proteomic analysis reveals rotator cuff injury caused by oxidative stress	14
Chinese traditional medicine (GuiZhi-ShaoYao-ZhiMu decoction) as an add-on medication to methotrexate for rheumatoid arthritis: a meta-analysis of randomized clinical trials	14
Computerized migraine diagnostic tools: a systematic review	14
Rheumatic immune-related adverse events associated with immune checkpoint inhibitors compared with placebo in oncologic patients: a systemic review and meta-analysis	13
A randomized, controlled trial on fenofibrate in primary biliary cholangitis patients with incomplete response to ursodeoxycholic acid	13
Segmental involvement of the corpus callosum in C9orf72-associated ALS: a tract of interest-based DTI study	13
Fecal microbiota transplantation treatment for type 1 diabetes mellitus with malnutrition: a case report	13
Are apolipoprotein E fragments a promising new therapeutic target for Alzheimer’s disease?	12
KDM4C contributes to cytarabine resistance in acute myeloid leukemia via regulating the miR-328-3p/CCND2 axis through MALAT1	12
Association of NAFLD with cardiovascular disease and all-cause mortality: a large-scale prospective cohort study based on UK Biobank	12
Endoscopic treatment for gastric antral vascular ectasia	12
Comparison of the triglyceride glucose (TyG) index, triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio, and metabolic score for insulin resistance (METS-IR) associated with periodon	12
The influence of delayed treatment due to COVID-19 on patients with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy	12
Preoperative malnutrition as an independent risk factor for the postoperative mortality in elderly Chinese individuals undergoing hip surgery: a single-center observational study	12
Impact of the chronic disease self-management program (CDSMP) on self-perceived frailty condition: the EU-EFFICHRONIC project	11
Sarcopenia and frailty combined increases the risk of mortality in patients with decompensated cirrhosis	11
Advances in the diagnosis and the management of primary hyperparathyroidism	11
EZH2 is involved in psoriasis progression by impairing miR-125a-5p inhibition of SFMBT1 and leading to inhibition of the TGFβ/SMAD pathway	11
Association between non-alcoholic fatty liver disease and risk of incident heart failure: a meta-analysis of observational studies	11
Nicotinamide supplementation in diabetic nonalcoholic fatty liver disease patients: randomized controlled trial	10
The five-repetition sit-to-stand test is a predictive factor of severe exacerbations in COPD	10
Increased IL-31 expression in serum and tissue protein in prurigo nodularis	10
Optimal cut-off points for adherence measure among patients with type 2 diabetes in primary care clinics: a retrospective analysis	10
ANCA-associated vasculitis following the CoronaVac vaccination	10
The effect of doxycycline on neuron-specific enolase in patients with traumatic brain injury: a randomized controlled trial	10
Early fibroproliferative signs on high-resolution CT are associated with mortality in COVID-19 pneumonia patients with ARDS: a retrospective study	9
Accessing behavioral health care during COVID: rapid transition from in-person to teleconferencing medical group visits	9
Review of current and future therapeutics in ABPA	9
Skin barrier status during dupilumab treatment in patients with severe atopic dermatitis	9
Metformin use is associated with low risk of case fatality and disability rates in first-ever stroke patients with type 2 diabetes	9
Long-term outcomes of antibiotic combination therapy for ulcerative colitis	9
Current situation and progress of drugs for reducing intraocular pressure	9
Multiple endocrine neoplasia 1: a broad overview	9
Comparisons of psychological distress and self-stigma among three types of substance use disorders receiving treatment-as-usual approaches: real-world data from a 9-month longitudinal study	9
Chronic obstructive pulmonary disease: moving from symptom relief to mortality reduction	8
The role of pre-emptive Transjugular Intrahepatic Portosystemic Shunt in acute variceal bleeding: a literature review	8
Advancements in prevention and intervention of sensorineural hearing loss	8
Remission and relapses of myasthenia gravis on long-term tacrolimus: a retrospective cross-sectional study of a Chinese cohort	8
Physical activity and the ‘pediatric inactivity triad’ in children living with chronic kidney disease: a narrative review	8
Metformin and the risk of dementia based on an analysis of 396,332 participants	8
Time-domain full-field optical coherence tomography (TD-FF-OCT) in ophthalmic imaging	8
Anemia, sarcopenia, physical activity, and the risk of tuberculosis in the older population: a nationwide cohort study	8
Effectiveness of using calligraphic activity to treat people with schizophrenia: a randomized controlled trial in Southern Taiwan	8

Optimal treatment strategies for coronary artery disease in patients with advanced kidney disease: a meta-analysis	8
Dupilumab and tezepelumab in severe refractory asthma: new opportunities	8
Twelve-month effects of everolimus on renal and lung function in lung transplantation: differences in chronic lung allograft dysfunction phenotypes	8
Impaired muscle capacity of the hip and knee in individuals with isolated patellofemoral osteoarthritis: a cross-sectional study	8
Transcranial alternating current stimulation and its effects on cognition and the treatment of psychiatric disorders: a systematic review and meta-analysis	8
Short- and long-term effects of whole-body photobiomodulation on pain, functionality, tissue quality, central sensitisation and psychological factors in a population suffering from fibromyalgia: proto	8
Are muscle weakness and stiffness risk factors of the development of rotator cuff tendinopathy in overhead athletes: a systematic review	8
Variants of SERPINA1 and the increasing complexity of testing for alpha-1 antitrypsin deficiency	8
Characteristics of tinnitus and factors influencing its severity	7
Prognostic implication of noninvasive right ventricle-to-pulmonary artery coupling in chronic thromboembolic pulmonary hypertension	7
Understanding racial differences of COPD patients with an ecological model: two large cohort studies in the US and Korea	7
Can acid exposure time replace the DeMeester score in the diagnosis of gastroesophageal reflux-induced cough?	7
Plasma ST6GAL1 regulates IgG sialylation to control IgA nephropathy progression	7
Changes of circulating biomarkers of inflammation and glycolipid metabolism by CPAP in OSA patients: a meta-analysis of time-dependent profiles	7
Advances and caveats in modern achalasia management	7
COVID-19-induced psoriatic arthritis: a case report	7
Effects of nonsurgical, minimally or noninvasive therapies for urinary incontinence due to neurogenic bladder: a systematic review and meta-analysis	7
Is Helicobacter pylori infection associated with pancreatic cancer? A systematic review and meta-analysis of observational studies	7
Efficacy of the use of unaffected hand containment in unimanual intensive therapy to increase visuomotor coordination in children with hemiplegia: a randomized controlled pilot study	7
Community-based screening to determine the prevalence, health and nutritional status of patients with CKD in rural and peri-urban Bangladesh	7
Fractional nitric oxide measurement in exhaled air (FeNO): perspectives in the management of respiratory diseases	7
Digital work engagement among Italian neurologists	7
Psychosomatic interactions in kidney transplantation: role of personality dimensions in mental health-related quality of life	7
Risk assessment in systemic lupus erythematosus-associated pulmonary arterial hypertension: CSTAR-PAH cohort study	7
One-year outcomes and predictive factors for primary patency after stent placement for treatment of central venous occlusive disease in hemodialysis patients	7
Neuropeptide Y: a potential theranostic biomarker for diabetic peripheral neuropathy in patients with type-2 diabetes	7
Cost-effectiveness of telemedicine care for patients with uncontrolled type 2 diabetes mellitus during the COVID-19 pandemic in Saudi Arabia	7
Hair repigmentation and regrowth in a dupilumab-treated paediatric patient with alopecia areata and atopic dermatitis: a case report	7
Vitamin C supplementation for the treatment of osteoarthritis: perspectives on the past, present, and future	6
Lung and liver transplantation in patients with alpha-1 antitrypsin deficiency	6
State of the art: non-invasive electrical stimulation for the treatment of chronic tinnitus	6
Physiotherapy interventions may relieve pain in individuals with central neuropathic pain: a systematic review and meta-analysis of randomised controlled trials	6
Efficacy and tolerability of infliximab retreatment in patients with inflammatory bowel disease: a systematic review and meta-analysis	6
Anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis complicated with macrophage activation syndrome	6
Relationship between long head of the biceps tendon histopathology and long-term functional results in smokers. A time to reevaluate the Bonar score?	6
A retrospective comparative study on arthroscopic suture anchors repair and tendon debridement versus arthroscopic tendon debridement for treatment of recalcitrant lateral epicondylitis	6
Post-authorisation safety study of burosumab use in paediatric, adolescent and adult patients with X-linked hypophosphataemia: rationale and description	6
Decreased numbers and sex-based differences of circulating regulatory T cells in patients with seropositive undifferentiated arthritis	6
Incidence, causes, and predictors of unsuccessful decannulation following prolonged weaning	6
Associated factors of potential drug-drug interactions and drug–food interactions in patients with multiple sclerosis	6
Cardiovascular diseases or type 2 diabetes mellitus and chronic airway diseases: mutual pharmacological interferences	6
Efficacy and potential predictors of vagus nerve stimulation therapy in refractory postencephalitic epilepsy	6
AES-CSFS: an automatic evaluation system for corneal sodium fluorescein staining based on deep learning	6
Application and observation of artificial intelligence in clinical practice of fundus screening for diabetic retinopathy with non-mydriatic fundus photography: a retrospective observational study of T	5
Prevalence, prescriptions, outcomes and costs of type 2 diabetes patients with or without prior coronary artery disease or stroke: a longitudinal 5-year claims-data analysis of over 7 million inhabita	5
Bimekizumab for the treatment of moderate-to-severe plaque psoriasis: a meta-analysis of randomized clinical trials	5
Development of a medication review tool for residents in Korean long-term care facilities	5
Serum fatty acids profile and association with early-onset coronary artery disease	5
Revascularization or medical therapy for stable coronary artery disease patients with different degrees of ischemia: a systematic review and meta-analysis of the role of myocardial perfusion	5
What is the role of Von Willebrand factor in chronic hepatitis B virus infection to hepatocellular carcinoma: a review article	5
Comparative efficacy of different noninvasive brain stimulation therapies for recovery of global cognitive function, attention, memory, and executive function after stroke: a network meta-analysis of	5
Microscopic colitis in older adults: impact, diagnosis, and management	5
The ipsilateral silent period: an early diagnostic marker of callosal disconnection in ALS	5
Outcomes of coronavirus 2019 infection in patients with chronic kidney disease: a systematic review and meta-analysis	5
Management of lung disease in alpha-1 antitrypsin deficiency: what we do and what we do not know	5
Diagnostic value of reflux episodes in gastroesophageal reflux-induced chronic cough: a novel predictive indicator	5
Liver disease with unknown etiology – have you ruled out alpha-1 antitrypsin deficiency?	5
Diabetes mellitus is associated with worse baseline and less post-treatment recovery of arterial stiffness in patients with primary aldosteronism	5
Cardiac manifestations of eosinophilic granulomatosis with polyangiitis from a single-center cohort in China: clinical features and associated factors	5
Prognostic factors in cancer patients infected with SARS-CoV-2: a Latin American country results	5
A cross-sectional study: an assessment of low muscle mass and osteoporosis in type 2 diabetes mellitus patients with a high glycated hemoglobin level	5
Identification of mortality-risk-related missense variant for renal clear cell carcinoma using deep learning	5
Association of Barrett’s esophagus with Helicobacter pylori infection: a meta-analysis	5
Associations between age-related hearing loss, cognitive decline, and depression in Chinese centenarians and oldest-old adults	5
Machine learning approaches for the mortality risk assessment of patients undergoing hemodialysis	4
Potential roles of gut microbiota and microbial metabolites in chronic inflammatory pain and the mechanisms of therapy drugs	4
Emerging roles of macrophages in heart failure and associated treatment approaches	4
Serum endocan and endothelial dysfunction in childhood acute lymphoblastic leukemia survivors: a tertiary center experience	4
How do phytocannabinoids affect cardiovascular health? An update on the most common cardiovascular diseases	4
Improved clinical outcomes of tocilizumab versus cyclophosphamide for IgG4-related disease: insights from a prospective IgG4-related disease registry	4
Ocular microvascular alteration in Sjögren’s syndrome treated with hydroxychloroquine: an OCTA clinical study	4
Novel homozygous mutation of PNLIP gene in congenital pancreatic lipase deficiency: an extended family study	4
Personalized medicine with drugs targeting the underlying protein defect in cystic fibrosis: is monitoring of treatment response necessary?	4
HbA1c trajectory and cardiovascular outcomes: an analysis of data from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) study	4
Hematological parameters and early-onset coronary artery disease: a retrospective case–control study based on 3366 participants	4
The spectrum of clinical sequelae associated with alpha-1 antitrypsin deficiency	4
First-line therapeutic strategy for patients with advanced non–small cell lung cancer with Leu858Arg epidermal growth factor receptor mutations: a Bayesian network meta-analysis	4
Inheritance and innovation of the diagnosis of peripheral pulmonary lesions	4
Degree of obesity and gastrointestinal adverse reactions influence the weight loss effect of liraglutide in overweight or obese patients with type 2 diabetes	4
Comparative risk of herpes zoster in patients with psoriatic disease on systemic treatments: a systematic review and network meta-analysis	4

Proteomic analysis of pulmonary arterial hypertension	4
The dawn phenomenon in type 2 diabetes: its association with glucose excursions and changes after oral glucose-lowering drugs	4
Association between thyroid hormones and skeletal muscle and bone in euthyroid type 2 diabetes patients	4
Characteristics and outcomes of patients with psoriasis treated with apremilast in the real-world in Austria – results the APPRECIATE study	4
Association of protein consumption and energy intake on sarcopenia in tuberculosis survivors	4
Relaxation-weighted 23Na magnetic resonance imaging maps regional patterns of abnormal sodium concentrations in amyotrophic lateral sclerosis	4
Associations between bone mineral density and coronary artery calcification: a systematic review and meta-analysis	4
Morphological alterations of the hypothalamus in idiopathic intracranial hypertension	4
RETRACTED: A meta-analysis of granulocyte-macrophage colony-stimulating factor (GM-CSF) antibody treatment for COVID-19 patients	4
Risk factors for the long-term incidence and progression of knee osteoarthritis in older adults: role of nonsurgical injury	4
Tocilizumab for faster and safer remission of Takayasu’s arteritis	4
Metformin adherence and the risk of cardiovascular disease: a population-based cohort study	4
Effect of TO901317 on GF to promote the differentiation of human bone marrow mesenchymal stem cells into dopamine neurons on Parkinson’s disease	4
Validity of serum and urinary hepcidin as biomarkers for late-onset sepsis in premature infants	4
Impact of local drug delivery and natural agents as new target strategies against periodontitis: new challenges for personalized therapeutic approach	4
The efficacy of telemedicine for pain management in patients with cancer: a systematic review and meta-analysis	4
Recalcitrant nodular scabies showing excellent response to tofacitinib: five case reports	3
Establishment of a preliminary FRAX®-based intervention threshold for rheumatoid arthritis–associated fragility fracture: a 3-year longitudinal, observational, cohort study	3
Blood pressure change and cognition in childhood and early adulthood: a systematic review	3
Renal outcomes and prognostic factors in patients with type-2 diabetes and chronic kidney disease confirmed by renal biopsy	3
The dynamics of the general practitioner-nephrologist collaboration for the management of patients with chronic kidney disease before and after dialysis initiation: a mixed-methods study	3
Exceptional response to lurbinectedin and irinotecan in BRCA-mutated platinum-resistant ovarian cancer patient: a case report	3
Designing a flow-controlled STA-MCA anastomosis based on the Hagen–Poiseuille law for preventing postoperative hyperperfusion in adult moyamoya disease	3
Multiple endocrine neoplasia 2: an overview	3
Prior percutaneous coronary intervention and outcomes in patients after coronary artery bypass grafting: a meta-analysis of 308,284 patients	3
Eosinophilia attention, diagnosis, treatment, and awareness in physicians: a cross-sectional survey	3
Sailing the ship of life: scurvy and autoimmunity . . .	3
Alpha-1 antitrypsin deficiency research and emerging treatment strategies: what’s down the road?	3
Novel therapies for proliferative retinopathies	3
Electronic patient-reported outcomes in clinical kidney practice (ePRO Kidney): a process evaluation of educational support for clinicians	3
New drugs in cystic fibrosis: what has changed in the last decade?	3
The optimal use of colon capsule endoscopes in clinical practice	3
Tolvaptan treatment in an adult Fontan patient with protein-losing enteropathy: a serial 23Na-MRI investigation	3
Anti-cyclic-citrullinated-protein-antibodies in psoriatic arthritis patients: how autoimmune dysregulation could affect clinical characteristics, retention rate of methotrexate monotherapy and first l	3
Chest X-ray features facilitate screening for pulmonary hypertension caused by fibrosing mediastinitis	3
An analysis report on the application of immune checkpoint inhibitors after liver transplantation	3
Comparison between 2D radiographic weight-bearing joint space width and 3D MRI non-weight-bearing cartilage thickness measures in the knee using non-weight-bearing 2D and 3D CT as an intermediary	3
Chronotherapy of cardiovascular pathologies: a hopeful strategy	3
Imaging in alpha-1 antitrypsin deficiency: a window into the disease	3
Impact of lack of face-to-face schooling during COVID-19 confinement on family quality of life of children with disabilities and typical development	3
Periprocedural, short-term, and long-term outcomes following transcatheter tricuspid valve repair: a systemic review and meta-analysis	3
A modified regimen of low-dose rituximab therapy for patients with refractory immune thrombocytopenia associated with systemic lupus erythematosus	3
Association between high-mobility group box 2 and subclinical hypertension-mediated organ damage in young adults	3
Distinguishing bronchoscopically observed anatomical positions of airway under by convolutional neural network	3
Efficacy of tacrolimus as long-term immunotherapy for neuronal surface antibody-mediated autoimmune encephalitis	3
Photodynamic therapy of cervical cancer: a scoping review on the efficacy of various molecules	3
Electrical stimulation to treat tinnitus: a meta-analysis and systemic review of randomized controlled trials	3
Autoimmune colitis and neutropenia in adjuvant anti-PD-1 therapy for malignant melanoma: efficacy of Vedolizumab, a case report	3
Strongyloidiasis: what every gastroenterologist needs to know	3