OOIR: Observatory of International Research

Papers

(The median citation count of DARU-Journal of Pharmaceutical Sciences is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Hybrid derivatives containing dimethyl fumarate and benzothiazole scaffolds for the potential treatment of multiple sclerosis; in silico & in vivo study	61
New psychoactive substances: a multidisciplinary review of challenges and their diverse character	32
Multi-functionalization of reduced graphene oxide nanosheets for tumor theragnosis: Synthesis, characterization, enzyme assay, in-silico study, radiolabeling and in vivo targeting evaluation	25
Dispersive micro-solid phase extraction based on two MOFs as highly effective adsorbents for analysis of nilotinib in plasma and wastewater	23
Effect of vitamins C and E on cancer survival; a systematic review	20
Lipid nanoparticles for gene therapy in ocular diseases	19
Co-delivery of SN38 and rapamycin albumin bound nanoparticles against breast Cancer	19
Evaluation of clinical and safety outcomes of generic tacrolimus (Suprotac $$\circledR$$) versus branded tacrolimus (Prograf $$\circledR$$) in de novo liver transplant patients: a randomized clinical	18
Stearyl amine tailored spanlastics embedded within tetronic® nanogel for boosting the repurposed anticancer potential of mebendazole: formulation, in vitro profiling, cytotoxicity assessment, and in v	18
Pharmacogenetic DPYD allele variant frequencies: A comprehensive analysis across an ancestrally diverse Iranian population	18
Oral regimen for high dose methotrexate urine alkalinization: a systematic review and meta-analysis	17
Impact of concerning excipients on animal safety: insights for veterinary pharmacotherapy and regulatory considerations	15
The effect of physical activity on epileptic seizures and consequentlearning and memory impairment in electrical amygdala kindling model	15
Cleaning validation in pharmaceutical quality control laboratories: a structured protocol for contamination risk mitigation	14
A comparison between SARS-CoV-1 and SARS-CoV2: an update on current COVID-19 vaccines	13
Structure based exploration of mitochondrial alpha carbonic anhydrase inhibitors as potential leads for anti-obesity drug development	12
Empowering the pharmaceutical industry by revolutionizing education	11
Co-delivery of artemisinin and metformin via PEGylated niosomal nanoparticles: potential anti-cancer effect in treatment of lung cancer cells	11
The impact of Rosa dmascena Mill. on gastrointestinal disorders: a comprehensive analysis through clinical trials, systematic review, and meta-analysis	11
Electrochemical evaluation of nivolumab used in cancer treatment with differential pulse voltammetry: A novel approach with single-use pencil graphite electrode	10
Ropivacaine suppresses the progression of renal cell carcinoma through regulating the lncRNA RMRP/EZH2/CCDC65 axis	9
Designing and psychometric evaluation of pharmacists' attitude toward ethical challenges questionnaire in pharmacy practice: A mixed‑method study	9
Comparative evaluation of different oral iron salts in the management of iron deficiency anemia	9
Repurposing metformin as a potential anticancer agent using in silico technique	9
In vitro evaluation of CeO2 nanoparticles on doxorubicin induced cardiotoxicity: focused on oxidative stress, inflammation, apoptosis, and mitochondrial function	8

Alpinumisoflavone against cancer pro-angiogenic targets: In silico, In vitro, and In ovo evaluation	8
High-performance liquid chromatography method for measuring Captopril: an empirical study on hydrogel film permeability test	7
Amorphous solid dispersions as a strategy to enhance the bioavailability and stability of formulations containing plant active ingredients: An integrative review	7
Vancomycin- induced leukocytoclastic vasculitis in a patient with end-stage renal disease: a case report and literature review	7
Developing an AI-based prediction model for anaphylactic shock from injection drugs using Japanese real-world data and chemical structure-based analysis	7
Silymarin sensitizes human colorectal cancer cells to 5-ALA–mediated photodynamic therapy by enhancing cytotoxicity and apoptotic signaling in vitro	7
Computational Screening Using a Combination of Ligand-Based Machine Learning and Molecular Docking Methods for the Repurposing of Antivirals Targeting the SARS-CoV-2 Main Protease	7
Innovative triamcinolone acetonide microsuspension for Non-Invasive ocular management of inflammation	6
Correction: Dexmedetomidine alleviates Hypoxia/reoxygenation-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/ Prdx3 pathway	6
Trends analysis and future study of the pharmaceutical industry field: a scoping review	6
Pre-emptive hydrocortisone therapy in early septic shock: a double-blind, allocation-concealed, pilot randomized controlled trial	6
Correction: Flavonoid as possible therapeutic targets against COVID-19: a scoping review of in silico studies	6
A neuroprotective dose of trehalose is harmless to metabolic organs: comprehensive histopathological analysis of liver, pancreas, and kidney	6
From code to cure: AI-Driven innovation in monoclonal antibody development	6
Network pharmacology: a systems perspective possible underpinning approach for oral cancer treatment	6
Efficacy of dostarlimab in recurrent or advanced mismatch Repair-Deficient endometrial Cancer as a Single-Agent therapy: A systematic review and Meta-Analysis	6
Adrenergic receptors blockade alleviates dexamethasone-induced neurotoxicity in adult male Wistar rats: Distinct effects on β-arrestin2 expression and molecular markers of neural injury	6
Nanoformulations in epilepsy therapy – a systematic review of emerging strategies in status epilepticus	5
Protective and therapeutic effects of Scutellaria baicalensis and its main active ingredients baicalin and baicalein against natural toxicities and physical hazards: a review of mechanisms	5
Mesoporous silica coated SPIONs containing curcumin and silymarin intended for breast cancer therapy	5
Imiquimod as a new treatment in refractory idiopathic granulomatous mastitis: report of two cases	5
Effectiveness of epigallocatechin gallate nanoparticles on the in-vivo treatment of Alzheimer’s disease in a rat/mouse model: a systematic review	5
Fibroblast growth factor 2 reduces endoplasmic reticulum stress and apoptosis in in-vitro Non-Alcoholic Fatty Liver Disease model	5
Chemical profiling and biological activities of the medicinal macrofungus Coriolopsis gallica: volatile, non-volatile, and fatty acid composition with antioxidant and in silico–supported anti-inflamma	5
Structure-activity relationship of pharmacophores and toxicophores: the need for clinical strategy	5
Clinical, humanistic, and economic outcomes of Passiflora alata Curtis use in participants with mild to moderate anxiety: a non-randomized experimental study	5
Novel biodegradable molecularly imprinted polymer nanoparticles for drug delivery of methotrexate anti-cancer; synthesis, characterization and cellular studies	4
Effect of blueberry extract on enhancement of radiosensitivity in non-Hodgkin lymphoma by modulating proliferation and apoptosis	4
Polymeric nanoparticles delivery circumvents bacterial resistance to ciprofloxacin	4
Therapeutic role of erythropoietin in methanol induced optic neuropathy: a systematic review	4
Plausible mechanism of drug resistance and side-effects of COVID-19 therapeutics: a bottleneck for its eradication	4
In silico screening, synthesis, characterization and biological evaluation of novel anticancer agents as potential COX-2 inhibitors	4
Trimethoprim/sulfamethoxazole desensitization in an HIV-positive patient with previous Stevens-Johnson syndrome; a failed study	4
Glatiramer acetate in situ forming gel, a new approach for multiple sclerosis treatment	4
Electroceuticals: Unlocking the promise of therapies	4
Development and evaluation of chitosan–xanthan gum-based controlled release nanoparticles of mebeverine hydrochloride for targeted IBS therapy: in silico, in vitro, and in vivo investigations	4
Freeze-drying of bupivacaine lipospheres: preparation, characterization, and evaluation of anti-microbial properties	4
Vactosertib potently improves anti-tumor properties of 5-FU for colon cancer	3
New amide and diterpene alkaloids with anticholinesterase activity from Delphinium cyphoplectrum roots	3
Dapsone improves the vincristine-induced neuropathic nociception by modulating neuroinflammation and oxidative stress	3
Flavonoid as possible therapeutic targets against COVID-19: a scoping review of in silico studies	3
A self-healable and bioadhesive acacia gum polysaccharide-based injectable hydrogel for wound healing acceleration	3
Plant-derived compounds as potential candidates for atrial fibrillation drug discovery: A review on phytochemicals with atrial-selective activity	3
Bioassay-Guided extraction of andrographis paniculata for intervention of in-vitro prostate cancer progression in metabolic syndrome environment	3
Investigation of the relationship between inflammation and microbiota in the intestinal tissue of female and male rats fed with fructose: Modulatory role of metformin	3
Safety assessment of the pharmacological excipient, diethylene glycol monoethyl ether (DEGEE), using in vitro and in vivo systems	3
Chidamide inhibits cell glycolysis in acute myeloid leukemia by decreasing N6-methyladenosine-related GNAS-AS1	3
Synthesis and optimization of fluoxetine-loaded polymeric nanoparticles for dual therapeutic applications in cancer and depression	3
Resveratrol and caffeic acid attenuate diet-induced obesity by inhibiting the SREBP-1/ACLY lipogenic axis in adipose tissue of rats	3
Prediction of naloxone dose in opioids toxicity based on machine learning techniques (artificial intelligence)	3

Towards greater impact in health technology assessment: System dynamic approach for new and emerging technologies in Iran	3
Advances in artificial intelligence-based technologies for increasing the quality of medical products	2
Drug repositioning: examining antipsychotic drugs and their anticancer effects	2
Dry powder inhaler design and particle technology in enhancing Pulmonary drug deposition: challenges and future strategies	2
Development of amphotericin B inclusion complex formulation in dissolvable microarray patches for intravaginal delivery	2
Comparison of different transient gene expression systems for the production of a new humanized anti-HER2 monoclonal antibody (Hersintuzumab)	2
Royal jelly and its hormonal effects in breast cancer: a literature review	2
Correction: Development of amphotericin B inclusion complex formulation in dissolvable microarray patches for intravaginal delivery	2
Utilization patterns of cardiovascular medications in patients with diabetes mellitus; a retrospective cross-sectional study, 2013-17	2
A critical overview of challenging roles of medicinal plants in improvement of wound healing technology	2
Firstly electrochemical investigetions and determination of anticoagulant drug edoxaban at single-use pencil graphite electrode: an eco-friendly and cost effective voltammetric method	2
The effect of Fe3O4 biosynthesized through the green synthesis of Silybum marianum and HA in the targeted delivery of 5-Fluorouracil to HCT116 cell line	2
Ameliorative effect of Melatonin on 5-Fluorouracil-induced reproductive toxicity in male rats	2
The NLRP3 inflammasome in osteoarthritis: a systematic review of traditional, complementary, and integrative medicine efficacy and underlying mechanisms	2
Atypical extrapyramidal manifestation of a typical antipsychotic with serotonergic antidepressant	2
An expert criticism on post-publication peer review platforms: the case of pubpeer	2
Cardiac safety profile of type II kinase inhibitors: Analysis of post-marketing reports from databases of European Medicine Agency & World Health Organization	2
Activity of zinc oxide and zinc borate nanoparticles against resistant bacteria in an experimental lung cancer model	2
Effect of the treatment of iron deficiency anemia on chronic drug-resistant cough: a rare case report	2
Prophylactic norepinephrine combined with 6% hydroxyethyl starch (130/0.4) co-load infusion for preventing postspinal anesthesia hypotension during cesarean section: a randomized, controlled, dose-fin	2
Clove volatile oil-loaded nanoemulsion reduces the anxious-like behavior in adult zebrafish	2
Assessment of potential drug interactions in rheumatology: a comparative study of decision support software	2