OOIR: Observatory of International Research

Papers

(The median citation count of DARU-Journal of Pharmaceutical Sciences is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Multi-functionalization of reduced graphene oxide nanosheets for tumor theragnosis: Synthesis, characterization, enzyme assay, in-silico study, radiolabeling and in vivo targeting evaluation	69
Hybrid derivatives containing dimethyl fumarate and benzothiazole scaffolds for the potential treatment of multiple sclerosis; in silico & in vivo study	37
Aprepitant’s neuroprotective effects on methylphenidate-induced biochemical/mitochondrial dysfunction, neuroinflammation, and mood-related behavior alterations	28
Effect of vitamins C and E on cancer survival; a systematic review	25
New psychoactive substances: a multidisciplinary review of challenges and their diverse character	25
Lipid nanoparticles for gene therapy in ocular diseases	24
Co-delivery of SN38 and rapamycin albumin bound nanoparticles against breast Cancer	21
Bridging solubility, stability, and translation: advances in carbon nanotube–based drug delivery systems	20
Evaluation of clinical and safety outcomes of generic tacrolimus (Suprotac $$\circledR$$) versus branded tacrolimus (Prograf $$\circledR$$) in de novo liver transplant patients: a randomized clinical	19
Pharmacogenetic DPYD allele variant frequencies: A comprehensive analysis across an ancestrally diverse Iranian population	19
Dispersive micro-solid phase extraction based on two MOFs as highly effective adsorbents for analysis of nilotinib in plasma and wastewater	19
Oral regimen for high dose methotrexate urine alkalinization: a systematic review and meta-analysis	17
Stearyl amine tailored spanlastics embedded within tetronic® nanogel for boosting the repurposed anticancer potential of mebendazole: formulation, in vitro profiling, cytotoxicity assessment, and in v	14
The effect of physical activity on epileptic seizures and consequentlearning and memory impairment in electrical amygdala kindling model	13
Impact of concerning excipients on animal safety: insights for veterinary pharmacotherapy and regulatory considerations	13
A comparison between SARS-CoV-1 and SARS-CoV2: an update on current COVID-19 vaccines	12
Cleaning validation in pharmaceutical quality control laboratories: a structured protocol for contamination risk mitigation	12
Structure based exploration of mitochondrial alpha carbonic anhydrase inhibitors as potential leads for anti-obesity drug development	12
Ropivacaine suppresses the progression of renal cell carcinoma through regulating the lncRNA RMRP/EZH2/CCDC65 axis	10
Empowering the pharmaceutical industry by revolutionizing education	10
Engineering microspheres for breast cancer: integrating tumor modeling, diagnostics, and targeted treatment	10
Comparative evaluation of different oral iron salts in the management of iron deficiency anemia	10
Co-delivery of artemisinin and metformin via PEGylated niosomal nanoparticles: potential anti-cancer effect in treatment of lung cancer cells	9
Electrochemical evaluation of nivolumab used in cancer treatment with differential pulse voltammetry: A novel approach with single-use pencil graphite electrode	9
Repurposing metformin as a potential anticancer agent using in silico technique	9

Alpinumisoflavone against cancer pro-angiogenic targets: In silico, In vitro, and In ovo evaluation	9
The impact of Rosa dmascena Mill. on gastrointestinal disorders: a comprehensive analysis through clinical trials, systematic review, and meta-analysis	9
Designing and psychometric evaluation of pharmacists' attitude toward ethical challenges questionnaire in pharmacy practice: A mixed‑method study	9
Vancomycin- induced leukocytoclastic vasculitis in a patient with end-stage renal disease: a case report and literature review	8
Silymarin sensitizes human colorectal cancer cells to 5-ALA–mediated photodynamic therapy by enhancing cytotoxicity and apoptotic signaling in vitro	8
Developing an AI-based prediction model for anaphylactic shock from injection drugs using Japanese real-world data and chemical structure-based analysis	8
High-performance liquid chromatography method for measuring Captopril: an empirical study on hydrogel film permeability test	8
Computational Screening Using a Combination of Ligand-Based Machine Learning and Molecular Docking Methods for the Repurposing of Antivirals Targeting the SARS-CoV-2 Main Protease	8
In vitro evaluation of CeO2 nanoparticles on doxorubicin induced cardiotoxicity: focused on oxidative stress, inflammation, apoptosis, and mitochondrial function	7
Amorphous solid dispersions as a strategy to enhance the bioavailability and stability of formulations containing plant active ingredients: An integrative review	7
Efficacy of dostarlimab in recurrent or advanced mismatch Repair-Deficient endometrial Cancer as a Single-Agent therapy: A systematic review and Meta-Analysis	7
Trends analysis and future study of the pharmaceutical industry field: a scoping review	7
Correction: Dexmedetomidine alleviates Hypoxia/reoxygenation-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/ Prdx3 pathway	7
Medication discrepancies and medication-related problems in psychiatric patients: A medication reconciliation study	7
Correction: Flavonoid as possible therapeutic targets against COVID-19: a scoping review of in silico studies	7
Adrenergic receptors blockade alleviates dexamethasone-induced neurotoxicity in adult male Wistar rats: Distinct effects on β-arrestin2 expression and molecular markers of neural injury	7
Chemical profiling and biological activities of the medicinal macrofungus Coriolopsis gallica: volatile, non-volatile, and fatty acid composition with antioxidant and in silico–supported anti-inflamma	6
A neuroprotective dose of trehalose is harmless to metabolic organs: comprehensive histopathological analysis of liver, pancreas, and kidney	6
Pre-emptive hydrocortisone therapy in early septic shock: a double-blind, allocation-concealed, pilot randomized controlled trial	6
Nanoformulations in epilepsy therapy – a systematic review of emerging strategies in status epilepticus	6
Network pharmacology: a systems perspective possible underpinning approach for oral cancer treatment	6
Nanoparticles of thiolated gum ghatti for the controlled ocular delivery of Ciprofloxacin	6
Innovative triamcinolone acetonide microsuspension for Non-Invasive ocular management of inflammation	6
Cephaeline promotes ferroptosis in breast cancer via p53/SLC7A11/GPX4 axis	6
From code to cure: AI-Driven innovation in monoclonal antibody development	6
Imiquimod as a new treatment in refractory idiopathic granulomatous mastitis: report of two cases	5
Mesoporous silica coated SPIONs containing curcumin and silymarin intended for breast cancer therapy	5
Effectiveness of epigallocatechin gallate nanoparticles on the in-vivo treatment of Alzheimer’s disease in a rat/mouse model: a systematic review	5
Structure-activity relationship of pharmacophores and toxicophores: the need for clinical strategy	5
Fibroblast growth factor 2 reduces endoplasmic reticulum stress and apoptosis in in-vitro Non-Alcoholic Fatty Liver Disease model	5
Clinical, humanistic, and economic outcomes of Passiflora alata Curtis use in participants with mild to moderate anxiety: a non-randomized experimental study	4
Plausible mechanism of drug resistance and side-effects of COVID-19 therapeutics: a bottleneck for its eradication	4
Therapeutic role of erythropoietin in methanol induced optic neuropathy: a systematic review	4
Development and evaluation of chitosan–xanthan gum-based controlled release nanoparticles of mebeverine hydrochloride for targeted IBS therapy: in silico, in vitro, and in vivo investigations	4
Freeze-drying of bupivacaine lipospheres: preparation, characterization, and evaluation of anti-microbial properties	4
Prediction of naloxone dose in opioids toxicity based on machine learning techniques (artificial intelligence)	4
Glatiramer acetate in situ forming gel, a new approach for multiple sclerosis treatment	4
Electroceuticals: Unlocking the promise of therapies	4
Effect of blueberry extract on enhancement of radiosensitivity in non-Hodgkin lymphoma by modulating proliferation and apoptosis	4
In silico screening, synthesis, characterization and biological evaluation of novel anticancer agents as potential COX-2 inhibitors	4
Investigation of the relationship between inflammation and microbiota in the intestinal tissue of female and male rats fed with fructose: Modulatory role of metformin	4
Polymeric nanoparticles delivery circumvents bacterial resistance to ciprofloxacin	4
Pharmaceutically engineered olfactory-masking agents: Innovating oral drug delivery through multisensory excipient design	4
Novel biodegradable molecularly imprinted polymer nanoparticles for drug delivery of methotrexate anti-cancer; synthesis, characterization and cellular studies	4
Therapeutic targeting of COX-2 in head and neck cancer: Mechanistic and clinical perspectives	4
A self-healable and bioadhesive acacia gum polysaccharide-based injectable hydrogel for wound healing acceleration	4
Trimethoprim/sulfamethoxazole desensitization in an HIV-positive patient with previous Stevens-Johnson syndrome; a failed study	4
ALKBH5 promotes the progression of cisplatin-resistant oral squamous cell carcinoma by regulating FOXA1 expression via m6A RNA methylation	4
An expert criticism on post-publication peer review platforms: the case of pubpeer	3
Flavonoid as possible therapeutic targets against COVID-19: a scoping review of in silico studies	3

Three-dimensional printing as a transformative platform for patient-centric pediatric drug delivery: technologies, formulation strategies and clinical translation	3
Synthesis and optimization of fluoxetine-loaded polymeric nanoparticles for dual therapeutic applications in cancer and depression	3
Vactosertib potently improves anti-tumor properties of 5-FU for colon cancer	3
A cost-efficient internal standard approach for busulfan quantification: MS-based investigation of adduct formation in therapeutic drug monitoring	3
Resveratrol and caffeic acid attenuate diet-induced obesity by inhibiting the SREBP-1/ACLY lipogenic axis in adipose tissue of rats	3
Bridging clinical toxicology and teratology: European survey of service integration	3
Chidamide inhibits cell glycolysis in acute myeloid leukemia by decreasing N6-methyladenosine-related GNAS-AS1	3
New amide and diterpene alkaloids with anticholinesterase activity from Delphinium cyphoplectrum roots	3
Towards greater impact in health technology assessment: System dynamic approach for new and emerging technologies in Iran	3
Dapsone improves the vincristine-induced neuropathic nociception by modulating neuroinflammation and oxidative stress	3
Bioassay-Guided extraction of andrographis paniculata for intervention of in-vitro prostate cancer progression in metabolic syndrome environment	3
Plant-derived compounds as potential candidates for atrial fibrillation drug discovery: A review on phytochemicals with atrial-selective activity	3
Firstly electrochemical investigetions and determination of anticoagulant drug edoxaban at single-use pencil graphite electrode: an eco-friendly and cost effective voltammetric method	2
Drug repositioning: examining antipsychotic drugs and their anticancer effects	2
A critical overview of challenging roles of medicinal plants in improvement of wound healing technology	2
Wistar rat model experiments for increasing intraocular pressure: a systematic review	2
Royal jelly and its hormonal effects in breast cancer: a literature review	2
The NLRP3 inflammasome in osteoarthritis: a systematic review of traditional, complementary, and integrative medicine efficacy and underlying mechanisms	2
Chitosan-carboxymethyl tara gum polyelectrolyte complex matrix tablets for sustained gastrointestinal drug dissolution using paracetamol as a model drug	2
Development of amphotericin B inclusion complex formulation in dissolvable microarray patches for intravaginal delivery	2
Advances in artificial intelligence-based technologies for increasing the quality of medical products	2
Atypical extrapyramidal manifestation of a typical antipsychotic with serotonergic antidepressant	2
Dry powder inhaler design and particle technology in enhancing Pulmonary drug deposition: challenges and future strategies	2
Comparison of different transient gene expression systems for the production of a new humanized anti-HER2 monoclonal antibody (Hersintuzumab)	2
Assessment of potential drug interactions in rheumatology: a comparative study of decision support software	2
Clove volatile oil-loaded nanoemulsion reduces the anxious-like behavior in adult zebrafish	2
The effect of Fe3O4 biosynthesized through the green synthesis of Silybum marianum and HA in the targeted delivery of 5-Fluorouracil to HCT116 cell line	2
Utilization patterns of cardiovascular medications in patients with diabetes mellitus; a retrospective cross-sectional study, 2013-17	2
Activity of zinc oxide and zinc borate nanoparticles against resistant bacteria in an experimental lung cancer model	2
Circadian-guided asthma therapy: compressed-coated chronotherapeutic tablets for precision early-morning drug delivery	2
Cardiac safety profile of type II kinase inhibitors: Analysis of post-marketing reports from databases of European Medicine Agency & World Health Organization	2
Effect of the treatment of iron deficiency anemia on chronic drug-resistant cough: a rare case report	2
Ameliorative effect of Melatonin on 5-Fluorouracil-induced reproductive toxicity in male rats	2
Correction: Development of amphotericin B inclusion complex formulation in dissolvable microarray patches for intravaginal delivery	2