OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Extracellular Vesicles is 59. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches	448
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles	222
A brief history of nearly EV‐erything – The rise and rise of extracellular vesicles	216
Formation of a protein corona on the surface of extracellular vesicles in blood plasma	206
Biodistribution of extracellular vesicles following administration into animals: A systematic review	199
Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles	188
Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin	174
RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?	155
Identification of storage conditions stabilizing extracellular vesicles preparations	154
Microbiota‐derived extracellular vesicles in interkingdom communication in the gut	133
Comprehensive evaluation of methods for small extracellular vesicles separation from human plasma, urine and cell culture medium	123
The impact of storage on extracellular vesicles: A systematic study	120
Covalent conjugation of extracellular vesicles with peptides and nanobodies for targeted therapeutic delivery	119
Engineered extracellular vesicles as versatile ribonucleoprotein delivery vehicles for efficient and safe CRISPR genome editing	117
Hypoxia and extracellular vesicles: A review on methods, vesicular cargo and functions	112
Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes	111
Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25	110
Extracellular vesicles containing ACE2 efficiently prevent infection by SARS‐CoV‐2 Spike protein‐containing virus	110
Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms	108
Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma – Contributions of platelet extracellular vesicles in plasma samples	106
Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: Present and future	105
Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy	105
A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation	102
Emerging methods in biomarker identification for extracellular vesicle‐based liquid biopsy	92
Extracellular vesicles: Natural liver‐accumulating drug delivery vehicles for the treatment of liver diseases	89

Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1‐targeting miRNA‐92a‐1‐5p	89
Extracellular vesicles from adipose tissue‐derived stem cells alleviate osteoporosis through osteoprotegerin and miR‐21‐5p	89
Highly‐metastatic colorectal cancer cell released miR‐181a‐5p‐rich extracellular vesicles promote liver metastasis by activating hepatic stellate cells and remodelling the tumour microenvironment	89
Preclinical efficacy and clinical safety of clinical‐grade nebulized allogenic adipose mesenchymal stromal cells‐derived extracellular vesicles	88
Human bronchial epithelial cell‐derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF‐β‐WNT crosstalk	87
Small extracellular vesicles released by infused mesenchymal stromal cells target M2 macrophages and promote TGF‐β upregulation, microvascular stabilization and functional recovery in a rodent model o	85
Quantification of protein cargo loading into engineered extracellular vesicles at single‐vesicle and single‐molecule resolution	84
Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe‐host‐communication in vivo	82
Roles of extracellular vesicles in the aging microenvironment and age‐related diseases	82
A call for Rigor and standardization in plant extracellular vesicle research	79
A bacterial extracellular vesicle‐based intranasal vaccine against SARS‐CoV‐2 protects against disease and elicits neutralizing antibodies to wild‐type and Delta variants	77
In sickness and in health: The functional role of extracellular vesicles in physiology and pathology in vivo	76
Plant‐derived extracellular vesicles: Recent advancements and current challenges on their use for biomedical applications	75
Characterization of brain‐derived extracellular vesicle lipids in Alzheimer's disease	74
Tumour‐derived extracellular vesicle membrane hybrid lipid nanovesicles enhance siRNA delivery by tumour‐homing and intracellular freeway transportation	71
Analysis of extracellular vesicle DNA at the single‐vesicle level by nano‐flow cytometry	71
Myocardial ischemia‐reperfusion induced cardiac extracellular vesicles harbour proinflammatory features and aggravate heart injury	71
Foetal bovine serum influence on in vitro extracellular vesicle analyses	69
Comparative analysis of tangential flow filtration and ultracentrifugation, both combined with subsequent size exclusion chromatography, for the isolation of small extracellular vesicles	66
Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy	65
In sickness and in health: The functional role of extracellular vesicles in physiology and pathology in vivo	65
Measuring particle concentration of multimodal synthetic reference materials and extracellular vesicles with orthogonal techniques: Who is up to the challenge?	65
Hypoxia‐stimulated ATM activation regulates autophagy‐associated exosome release from cancer‐associated fibroblasts to promote cancer cell invasion	65
Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer‐based precipitation and size exclusion chromatography	65
Human neural cell type‐specific extracellular vesicle proteome defines disease‐related molecules associated with activated astrocytes in Alzheimer's disease brain	64
Extracellular vesicle‐mediated endothelial apoptosis and EV‐associated proteins correlate with COVID‐19 disease severity	64
Extracellular vesicles carry SARS‐CoV‐2 spike protein and serve as decoys for neutralizing antibodies	62
Active cargo loading into extracellular vesicles: Highlights the heterogeneous encapsulation behaviour	62
Functional assays to assess the therapeutic potential of extracellular vesicles	62
Proteomic dissection of large extracellular vesicle surfaceome unravels interactive surface platform	62
Specific anti‐glioma targeted‐delivery strategy of engineered small extracellular vesicles dual‐functionalised by Angiopep‐2 and TAT peptides	61
Engineering extracellular vesicles by three‐dimensional dynamic culture of human mesenchymal stem cells	61
Single‐vesicle imaging and co‐localization analysis for tetraspanin profiling of individual extracellular vesicles	61
A compendium of single extracellular vesicle flow cytometry	60
Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes	59