OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Extracellular Vesicles is 56. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles	181
Biodistribution of extracellular vesicles following administration into animals: A systematic review	155
A brief history of nearly EV‐erything – The rise and rise of extracellular vesicles	151
Formation of a protein corona on the surface of extracellular vesicles in blood plasma	150
Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles	148
miR‐23a‐3p‐abundant small extracellular vesicles released from Gelma/nanoclay hydrogel for cartilage regeneration	142
Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin	135
RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?	130
A combined “eat me/don't eat me” strategy based on extracellular vesicles for anticancer nanomedicine	122
Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging	115
Extracellular vesicles containing ACE2 efficiently prevent infection by SARS‐CoV‐2 Spike protein‐containing virus	102
Microbiota‐derived extracellular vesicles in interkingdom communication in the gut	100
Covalent conjugation of extracellular vesicles with peptides and nanobodies for targeted therapeutic delivery	99
Engineered extracellular vesicles as versatile ribonucleoprotein delivery vehicles for efficient and safe CRISPR genome editing	99
Comprehensive evaluation of methods for small extracellular vesicles separation from human plasma, urine and cell culture medium	98
Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25	95
Extracellular vesicles from human iPSC‐derived neural stem cells: miRNA and protein signatures, and anti‐inflammatory and neurogenic properties	94
Hypoxia and extracellular vesicles: A review on methods, vesicular cargo and functions	94
Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms	93
Identification of storage conditions stabilizing extracellular vesicles preparations	90
Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes	89
The impact of storage on extracellular vesicles: A systematic study	85
A novel three step protocol to isolate extracellular vesicles from plasma or cell culture medium with both high yield and purity	83
Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy	79
Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: Present and future	78

Extracellular vesicles from adipose tissue‐derived stem cells alleviate osteoporosis through osteoprotegerin and miR‐21‐5p	77
Exosomes derived from neural progenitor cells preserve photoreceptors during retinal degeneration by inactivating microglia	76
Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1‐targeting miRNA‐92a‐1‐5p	74
Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma – Contributions of platelet extracellular vesicles in plasma samples	74
Emerging methods in biomarker identification for extracellular vesicle‐based liquid biopsy	74
Highly‐metastatic colorectal cancer cell released miR‐181a‐5p‐rich extracellular vesicles promote liver metastasis by activating hepatic stellate cells and remodelling the tumour microenvironment	73
Extracellular vesicles: Natural liver‐accumulating drug delivery vehicles for the treatment of liver diseases	73
Preclinical efficacy and clinical safety of clinical‐grade nebulized allogenic adipose mesenchymal stromal cells‐derived extracellular vesicles	73
The future of Extracellular Vesicles as Theranostics – an ISEV meeting report	73
Monitoring HSP70 exosomes in cancer patients’ follow up: a clinical prospective pilot study	72
Human bronchial epithelial cell‐derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF‐β‐WNT crosstalk	72
Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration	71
Small extracellular vesicles released by infused mesenchymal stromal cells target M2 macrophages and promote TGF‐β upregulation, microvascular stabilization and functional recovery in a rodent model o	71
A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation	71
Influence of species and processing parameters on recovery and content of brain tissue‐derived extracellular vesicles	69
Lactobacillus plantarum‐derived extracellular vesicles induce anti‐inflammatory M2 macrophage polarization in vitro	68
A circulating extracellular vesicles‐based novel screening tool for colorectal cancer revealed by shotgun and data‐independent acquisition mass spectrometry	67
Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe‐host‐communication in vivo	66
A call for Rigor and standardization in plant extracellular vesicle research	66
Systematic review of extracellular vesicle‐based treatments for lung injury: are EVs a potential therapy for COVID‐19?	64
Dendritic cell derived exosomes loaded with immunoregulatory cargo reprogram local immune responses and inhibit degenerative bone disease in vivo	63
Myocardial ischemia‐reperfusion induced cardiac extracellular vesicles harbour proinflammatory features and aggravate heart injury	62
Triple knockdown of CDC37, HSP90‐alpha and HSP90‐beta diminishes extracellular vesicles‐driven malignancy events and macrophage M2 polarization in oral cancer	61
Characterization of brain‐derived extracellular vesicle lipids in Alzheimer's disease	61
Roles of extracellular vesicles in the aging microenvironment and age‐related diseases	60
Quantification of protein cargo loading into engineered extracellular vesicles at single‐vesicle and single‐molecule resolution	59
In sickness and in health: The functional role of extracellular vesicles in physiology and pathology in vivo	59
Exosome therapeutics for lung regenerative medicine	59
Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles	59
Small RNA fingerprinting of Alzheimer's disease frontal cortex extracellular vesicles and their comparison with peripheral extracellular vesicles	58
Extracellular vesicle‐mediated endothelial apoptosis and EV‐associated proteins correlate with COVID‐19 disease severity	58
Mesenchymal stromal cell‐derived small extracellular vesicles restore lung architecture and improve exercise capacity in a model of neonatal hyperoxia‐induced lung injury	56
Measuring particle concentration of multimodal synthetic reference materials and extracellular vesicles with orthogonal techniques: Who is up to the challenge?	56
Foetal bovine serum influence on in vitro extracellular vesicle analyses	56