OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Extracellular Vesicles is 59. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-07-01 to 2024-07-01.)

Article	Citations
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches	210
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles	203
Formation of a protein corona on the surface of extracellular vesicles in blood plasma	182
A brief history of nearly EV‐erything – The rise and rise of extracellular vesicles	178
Biodistribution of extracellular vesicles following administration into animals: A systematic review	178
Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles	167
Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin	157
RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?	145
A combined “eat me/don't eat me” strategy based on extracellular vesicles for anticancer nanomedicine	131
Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging	126
Microbiota‐derived extracellular vesicles in interkingdom communication in the gut	119
Identification of storage conditions stabilizing extracellular vesicles preparations	118
Comprehensive evaluation of methods for small extracellular vesicles separation from human plasma, urine and cell culture medium	110
Covalent conjugation of extracellular vesicles with peptides and nanobodies for targeted therapeutic delivery	110
Engineered extracellular vesicles as versatile ribonucleoprotein delivery vehicles for efficient and safe CRISPR genome editing	108
Extracellular vesicles containing ACE2 efficiently prevent infection by SARS‐CoV‐2 Spike protein‐containing virus	104
Extracellular vesicles from human iPSC‐derived neural stem cells: miRNA and protein signatures, and anti‐inflammatory and neurogenic properties	102
Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25	102
Hypoxia and extracellular vesicles: A review on methods, vesicular cargo and functions	102
The impact of storage on extracellular vesicles: A systematic study	102
Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms	101
Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes	100
Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma – Contributions of platelet extracellular vesicles in plasma samples	94
Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: Present and future	93
A novel three step protocol to isolate extracellular vesicles from plasma or cell culture medium with both high yield and purity	92

Staphylococcus aureus membrane vesicles contain immunostimulatory DNA, RNA and peptidoglycan that activate innate immune receptors and induce autophagy	91
A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation	89
Emerging methods in biomarker identification for extracellular vesicle‐based liquid biopsy	85
Preclinical efficacy and clinical safety of clinical‐grade nebulized allogenic adipose mesenchymal stromal cells‐derived extracellular vesicles	84
Human bronchial epithelial cell‐derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF‐β‐WNT crosstalk	83
Extracellular vesicles from adipose tissue‐derived stem cells alleviate osteoporosis through osteoprotegerin and miR‐21‐5p	82
Highly‐metastatic colorectal cancer cell released miR‐181a‐5p‐rich extracellular vesicles promote liver metastasis by activating hepatic stellate cells and remodelling the tumour microenvironment	81
The future of Extracellular Vesicles as Theranostics – an ISEV meeting report	80
Extracellular vesicles: Natural liver‐accumulating drug delivery vehicles for the treatment of liver diseases	80
Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1‐targeting miRNA‐92a‐1‐5p	78
Small extracellular vesicles released by infused mesenchymal stromal cells target M2 macrophages and promote TGF‐β upregulation, microvascular stabilization and functional recovery in a rodent model o	76
Towards defining reference materials for measuring extracellular vesicle refractive index, epitope abundance, size and concentration	76
Visualizing transfer of microbial biomolecules by outer membrane vesicles in microbe‐host‐communication in vivo	74
Lactobacillus plantarum‐derived extracellular vesicles induce anti‐inflammatory M2 macrophage polarization in vitro	74
In sickness and in health: The functional role of extracellular vesicles in physiology and pathology in vivo	72
A call for Rigor and standardization in plant extracellular vesicle research	72
Roles of extracellular vesicles in the aging microenvironment and age‐related diseases	71
Quantification of protein cargo loading into engineered extracellular vesicles at single‐vesicle and single‐molecule resolution	70
Dendritic cell derived exosomes loaded with immunoregulatory cargo reprogram local immune responses and inhibit degenerative bone disease in vivo	70
A bacterial extracellular vesicle‐based intranasal vaccine against SARS‐CoV‐2 protects against disease and elicits neutralizing antibodies to wild‐type and Delta variants	68
Characterization of brain‐derived extracellular vesicle lipids in Alzheimer's disease	68
Systematic review of extracellular vesicle‐based treatments for lung injury: are EVs a potential therapy for COVID‐19?	67
Myocardial ischemia‐reperfusion induced cardiac extracellular vesicles harbour proinflammatory features and aggravate heart injury	66
Foetal bovine serum influence on in vitro extracellular vesicle analyses	64
Tumour‐derived extracellular vesicle membrane hybrid lipid nanovesicles enhance siRNA delivery by tumour‐homing and intracellular freeway transportation	64
Extracellular vesicle‐mediated endothelial apoptosis and EV‐associated proteins correlate with COVID‐19 disease severity	62
Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy	61
Experimental artefacts can lead to misattribution of bioactivity from soluble mesenchymal stem cell paracrine factors to extracellular vesicles	61
Mesenchymal stromal cell‐derived small extracellular vesicles restore lung architecture and improve exercise capacity in a model of neonatal hyperoxia‐induced lung injury	60
Measuring particle concentration of multimodal synthetic reference materials and extracellular vesicles with orthogonal techniques: Who is up to the challenge?	60
Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer‐based precipitation and size exclusion chromatography	60
Analysis of extracellular vesicle DNA at the single‐vesicle level by nano‐flow cytometry	59
Plasma extracellular vesicles detected by Single Molecule array technology as a liquid biopsy for colorectal cancer	59
Human neural cell type‐specific extracellular vesicle proteome defines disease‐related molecules associated with activated astrocytes in Alzheimer's disease brain	59
In sickness and in health: The functional role of extracellular vesicles in physiology and pathology in vivo	59