Clinical and Translational Medicine

Papers
(The TQCC of Clinical and Translational Medicine is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-07-01 to 2026-07-01.)
ArticleCitations
Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation404
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design351
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC154
151
HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC148
122
Sendotypes predict worsening renal function in chronic kidney disease patients116
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging114
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway101
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma98
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease97
Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma95
MicroRNAs affecting the susceptibility of melanoma cells to CD8+ T cell‐mediated cytolysis93
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor92
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma92
Multi‐omics analysis revealed biomarkers for coronary atherosclerosis: Occurrence and development88
A droplet that releases stress: Drop‐printing for conformal bioelectronics at neural and soft‐tissue interfaces82
Predictive medicine in a testis trio‐family through a combined multi‐omics approach79
Macrophage Cluster of Differentiation 163 promotes post‐infarction cardiac repair and preserves left ventricular function via osteopontin79
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases76
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing75
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases71
Illuminating the genomic frontier of invasive non‐typhoidal Salmonella infections71
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives69
Clinical translation potential of self‐inspired live‐cell super‐resolution microscopy69
Regulatory mechanism of O‐linked N‐acetylglucosamine protein modification on autophagy in cancer68
Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer64
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells64
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients63
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma62
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma61
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis61
Targeting lysine methyltransferase 2C deficiency: New frontiers in breast cancer therapy and prognosis61
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma60
The biological burden of conflict across populations worldwide60
Faecal zonulin, calprotectin and the infant microbiome in early life59
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways59
Effect of epigenetic treatment on SST2 expression in neuroendocrine tumour patients58
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target55
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome55
Quantum biology: From mechanisms to medicine54
Seize the engine: Emerging cell cycle targets in breast cancer54
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma54
Ubc9‐mediated SUMOylation of Ninj1 alleviates inflammatory responses in hepatic ischaemia/reperfusion injury54
Mitochondrial and immune response dysregulation in melanoma recurrence54
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia52
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA52
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca2+ signalling50
The deubiquitinase OTUD3 plays a neuroprotective role by reducing ferroptosis induced by cerebral ischaemia reperfusion via stabilizing PLK1 via deubiquitination50
Deciphering the secret codes in N7‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases49
48
48
NDP‐βdmanno‐heptoses are small molecule agonists sensed by the vertebrates to discriminate organisms of different kingdoms48
Synergistic inhibition of progesterone receptor‐A/B signalling by simvastatin and mifepristone in human uterine leiomyomas48
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation48
Multi‐omics molecular phenotyping reveals the potential mechanisms of chemotherapy response and resistance in small cell lung cancer48
Role of the FOXM1/CMA/ER stress axis in regulating the progression of nonalcoholic steatohepatitis47
Predicted early fusion intermediates in the spike of ACE2‐utilising bat coronavirus unveil broad‐spectrum antiviral mechanisms47
Dynamics of the intratumoural microbiome across malignant transformation and treatment in breast cancer46
Inhibition of autophagy antagonizes breast cancer brain metastogenesis and augments the anticancer activity of lapatinib46
OXA1L deficiency causes mitochondrial myopathy via reactive oxygen species regulated nuclear factor kappa B signalling pathway46
Tumour‐targeted fluorescence‐guided surgery in gastrointestinal cancer: A systematic review of preclinical and clinical research45
Unmasking the tumourigenic role of SIN1/MAPKAP1 in the mTOR complex 245
ALKBH3 suppresses ischemia/reperfusion‐induced PANoptosis by regulating the ZBED6/STAT1/AIM2 axis through m 1 A demethylation45
Unlocking the potential of T‐cell metabolism reprogramming: Advancing single‐cell approaches for precision immunotherapy in tumour immunity45
Identification of the c‐Jun/H19/miR‐19/JNK1 cascade during hepatic stellate cell activation45
Translational inhalable extracellular vesicle‐based mRNA therapy for the treatment of lung cancer43
Major cell types in the coronary thrombosis of acute myocardial infarction patients revealed by scRNA‐seq43
Plasma tsRNAs as novel diagnostic biomarkers for renal cell carcinoma43
Nanopore sequencing with T2T‐CHM13 for accurate detection and preventing the transmission of structural rearrangements in highly repetitive heterochromatin regions in human embryos42
Erratum to “Clinic‐ready inhibitor of MMP−9/−12 restores sensory and functional decline in rodent models of spinal cord injury”42
Inhibition of proteasomal deubiquitinases USP14 and UCHL5 overcomes tyrosine kinase inhibitor resistance in chronic myeloid leukaemia41
Nano‐optogenetic immunotherapy41
Blockade of V‐domain immunoglobulin suppressor of T‐cell activation reprograms tumour‐associated macrophages and improves efficacy of PD‐1 inhibitor in gastric cancer41
Pericardial delta like non‐canonical NOTCH ligand 1 (Dlk1) augments fibrosis in the heart through epithelial to mesenchymal transition41
KDM6A promotes hepatocellular carcinoma progression and dictates lenvatinib efficacy by upregulating FGFR4 expression41
CAR‐DC combined with CAR‐T therapy for relapsed/refractory acute myeloid leukaemia: Research progress and future perspectives41
Niacin promotes motor function recovery after spinal cord injury via Hcar2‐dependent microglia immunometabolic regulation40
Genomic classification of intrapulmonary metastasis and multiple primary lung cancer40
Fibroblast growth factor 10 attenuates advanced liver fibrosis through hepatocyte fibroblast growth factor receptor 2 signalling40
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of AGTR1+CAFs in intrahepatic cholangiocarcinoma40
Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer40
Adipocyte fatty acid‐binding protein as a cerebrospinal fluid–accessible biomarker and druggable target in subarachnoid haemorrhage: Linking fatty acid dysregulation to microglial neuroinflammation40
Combination anti‐HIV antibodies to achieve antiretroviral therapy‐free virological suppression in infected individuals39
The m5C methyltransferase NSUN2 promotes codon‐dependent oncogenic translation by stabilising tRNA in anaplastic thyroid cancer39
Long‐term survival and association of neoadjuvant chemotherapy with or without immunotherapy in resectable esophageal squamous cell carcinoma39
17‐β‐estradiol reduces surface PD‐L1 expression in estrogen receptor‐positive breast cancer but not type 1 endometrial cancer cells39
Illuminating spatial pharmacology with in situ drug imaging39
In vitro reconstitution of SPO11‐mediated DNA cleavage reveals mechanistic and clinical insights into meiotic DNA double‐strand break formation39
WDR62 variants contribute to congenital heart disease by inhibiting cardiomyocyte proliferation38
Severe dengue in children associates with dysregulation of lipid homeostasis, complement cascade and retinol transport38
Cellular dynamics in tumour microenvironment along with lung cancer progression underscore spatial and evolutionary heterogeneity of neutrophil38
37
37
37
Gestational weight gain in pregnant women with obesity is associated with cord blood DNA methylation, which partially mediates offspring anthropometrics37
Brain cholesterol therapy for Huntington's disease – Does it make sense?37
Efficacy and safety of pyrotinib combined with albumin‐bound paclitaxel as first‐line treatment for HER2‐positive metastatic breast cancer in patients previously treated with adjuvant and/or neoadjuva37
Gene signature related to cancer stem cells and fibroblasts of stem‐like gastric cancer predicts immunotherapy response36
The potential of gas plasma technology for targeting breast cancer36
The rise of marine fungi: Drug discovery's blue frontier36
Downregulation of SENP1 impairs nuclear condensation of MEF2C and deteriorates ischemic cardiomyopathy36
Involvement of MST1/mTORC1/STAT1 activity in the regulation of B‐cell receptor signalling by chemokine receptor 236
Pathogen sharing in the digital age: The unfinished agenda of the WHO pandemic agreement36
The role of long non‐coding RNAs in lung cancer metastasis: Molecular mechanisms, pathogenesis and clinical implications35
Oncogenic PIK3CA recruits myeloid‐derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5‐lipoxygenase‐dependent arachidonic acid pathway35
Evaluation of on‐ and off‐target effects of self‐assembled epidermal growth factor receptor small interfering RNA delivery system34
Human mesenchymal stem‐derived extracellular vesicles improve body growth and motor function following severe spinal cord injury in rat34
Lysophosphatidylcholine inhibits lung cancer cell proliferation by regulating fatty acid metabolism enzyme long‐chain acyl‐coenzyme A synthase 534
Transcriptomic profiling reveals the dynamics of fibrotic progression‐related gene expression into post‐coronavirus disease 2019 pulmonary fibrosis34
Microbial and human transcriptome in vaginal fluid at midgestation: Association with spontaneous preterm delivery34
Vitamin D receptor activation in microglia suppresses NOX2‐mediated oxidative damage via PAT1 in vitro and in vivo34
Therapeutic targeting of CNBP phase separation inhibits ribosome biogenesis and neuroblastoma progression via modulating SWI/SNF complex activity33
Single‐cell RNA sequencing reveals cellular and molecular reprograming landscape of gliomas and lung cancer brain metastases32
Natural killer cell engagers: From bi‐specific to tri‐specific and tetra‐specific engagers for enhanced cancer immunotherapy32
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple‐negative breast cancer progression via an m6A‐dependent manner32
CLINICAL AND TRANSLATIONAL MEDICINE32
Transcriptomic evidence of lung repair in paediatric ARDS survival32
A randomized, double‐blind phase 1b study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of the NLRP3 inhibitor selnoflast in patients with moderate to severe active ulcera32
Transcriptomic analysis for the retested positive COVID‐19 patients with long‐term persistent SARS‐CoV‐2 but without symptoms in Wuhan31
A living biobank of sarcoma patient‐derived cell cultures reveals multi‐omic and functional insights that capture disease heterogeneity31
Ubiquitous regulation of cerebrovascular diseases by ubiquitin‐modifying enzymes31
Spatial‒temporal heterogeneities of liver cancer and the discovery of the invasive zone31
Single‐cell sequencing of multi‐region resolves geospatial architecture and therapeutic target of endothelial cells in esophageal squamous cell carcinoma31
Multi‐omics analysis of pyroptosis‐related genes for prognosis and immune landscape in head and neck cancer30
How the brain produces generalized fear30
Identification of hypoxic macrophages in glioblastoma: Unveiling therapeutic insights from tumour microenvironment analysis30
Targeting the MDK/c‐Myc complex to overcome temozolomide resistance in glioma30
Metastasis ability, genomic profile, subtype characteristic and curative efficacy of multiple pulmonary hematogenous metastases in lung cancer30
Human umbilical cord mesenchymal stem cells therapy alleviates kidney injury and podocyte apoptosis in Col4a5 knockout male mice30
Dynamic alterations of ctDNA associate with the therapeutic outcome in the advanced non‐small cell lung cancer patients who received sintilimab plus anlotinib regime as 1st line therapy30
30
Neuronal loss drives differentially expressed protein‐pathways in the PSP globus pallidus29
Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies29
P2X7R deficiency alleviates cardiac senescence by enhancing mitophagy via the HuR/TRIM26/NR4A1 axis29
Circular RNA LIPH promotes pancreatic cancer glycolysis and progression through sponge miR‐769‐3p and interaction with GOLM129
Ensemble biomarkers for guiding anti‐angiogenesis therapy for ovarian cancer using deep learning29
Managing noradrenaline after traumatic brain injury29
Sphingosine 1‐phosphate lyase facilitates cancer progression through converting sphingolipids to glycerophospholipids29
T‐cell differentiation stage block bias confers hypermethylation and mediastinal preference in T‐cell lymphoblastic lymphoma28
Hepatic interleukin‐1 receptor type 1 signalling regulates insulin sensitivity in the early phases of nonalcoholic fatty liver disease28
SAA1 and metabolomic signatures predict hyperprogression with immunotherapy in pan cancers28
Tumour organoids and assembloids: Patient‐derived cancer avatars for immunotherapy28
CRBN is downregulated in lung cancer and negatively regulates TLR2, 4 and 7 stimulation in lung cancer cells28
BRAFV600E‐PROTAC versus inhibitors in melanoma cells: Deep transcriptomic characterization28
Single‐cell and bulk characterisation of the distinct immune landscape and possible regulatory mechanisms in coronary plaques vulnerability28
Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts27
Integrated multi‐omics profiling landscape of organising pneumonia27
Targeting c‐Myc enhances immunotherapy efficacy in combination with Ras inhibitor in triple‐negative breast cancer27
OTUB1 inhibits breast cancer by non‐canonically stabilizing CCN627
Issue Information27
Evaluation of pulmonary single‐cell identity specificity in scRNA‐seq analysis27
RNA interference therapy for targeting ANGPTL3 and atherogenic lipoproteins: Findings and implications of a recent phase I study27
Evaluation of vaccine effectiveness against SARS‐CoV‐2 variants by serological epitope profiling27
Crosstalk between m6A modification and alternative splicing during cancer progression27
Spatial and single‐cell RNA sequencing reveals the immune microenvironment of human ascending thoracic aortic aneurysms27
Single‐nucleus and spatial transcriptomics of paediatric ovary: Molecular insights into the dysregulated signalling pathways underlying premature ovarian insufficiency in classic galactosemia27
Improving detection of colorectal cancer: A Bayesian approach to serial circulating tumour DNA testing following curative‐intent treatment.27
Correction to VEGF‐C/VEGFR‐3 axis protects against pressure‐overload‐induced cardiac dysfunction through regulation of lymphangiogenesis26
Two 18‐norspirostane steroidal saponins as novel mitophagy enhancers improve Alzheimer's disease26
Systemic lupus erythematosus extends beyond a type I interferonopathy, as demonstrated by NET‐activated monocytes26
Identification of growth hormone receptor as a relevant target for precision medicine in low‐EGFR expressing glioblastoma26
Issue Information26
Small molecule Z363 co‐regulates TAF10 and MYC via the E3 ligase TRIP12 to suppress tumour growth26
Advancing standards in biomedical image analysis validation: A perspective on Metrics Reloaded26
Interleukin‐2/anti‐interleukin‐2 immune complex attenuates cold ischemia‐reperfusion injury after kidney transplantation by increasing renal regulatory T cells26
Integrated multi‐regional multiomic profiling of breast phyllodes tumours reveals peritumoural immune activation and stromal remodelling26
Machine learning‐based multi‐omics models for diagnostic classification and risk stratification in diabetic kidney disease26
Plasma cell‐free DNA markers predict occult metastases in patients with resectable pancreatic ductal adenocarcinoma26
Translational potential of human brain charts26
Snai2‐mediated upregulation of NADSYN1 promotes bladder cancer progression by interacting with PHB25
Clinical predictive factors and prediction models for end‐stage renal disease in Chinese patients with type 2 diabetes mellitus25
Metabolomics signature as a survival predictor in patients with resectable colorectal liver metastasis25
Mutations of epigenetic genes and correlation with treatment response in peripheral T‐cell lymphoma25
The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia25
Smad3‐mediated lncRNA HSALR1 enhances the non‐classic signalling pathway of TGF‐β1 in human bronchial fibroblasts by binding to HSP90AB125
RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner25
Urinary DNA methylation‐based risk stratification model to triage patients for repeat transurethral resection of bladder tumours25
25
CircSpna2 attenuates cuproptosis by mediating ubiquitin ligase Keap1 to regulate the Nrf2‐Atp7b signalling axis in depression after traumatic brain injury in a mouse model25
Interleukin‐11 promotes lung adenocarcinoma tumourigenesis and immune evasion25
Single‐cell transcriptome analysis reveals functional changes in tumour‐infiltrating B lymphocytes after chemotherapy in oesophageal squamous cell carcinoma25
Itaconate suppresses neonatal intestinal inflammation via metabolic reprogramming of M1 macrophage25
Glutamate as a therapeutic strategy to promote liver regeneration25
CDK7 inhibition promotes glioblastoma cell death through convergent transcriptional and metabolic stress pathways25
Diagnostic and therapeutic potential of tonic gamma‐aminobutyric acid from reactive astrocytes in brain diseases24
Human gut‐associated lymphoid tissue: A dynamic hub propagating modulators of inflammation24
HepAssis2 ® bioartificial liver system in treating acute‐on‐chronic liver failure patients: Findings from a phase 1 randomised, open‐label clinical t24
Spliceosomal profiling identifies EIF4A3 as a novel oncogene in hepatocellular carcinoma acting through the modulation of FGFR4 splicing24
TMEM92 shields DDX3X from TTC3‐mediated degradation to confer chemoresistance in triple‐negative breast cancer24
MiRNA‐501‐3p and MiRNA‐502‐3p: A promising biomarker panel for Alzheimer's disease24
Hypoxia‐induced PGK1 expression promotes esophageal squamous cell carcinoma progression via stimulating MYH9‐mediated GSK3β/β‐catenin signalling24
YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM224
Issue Information23
Unconventional microRNA role: Enhancing the human leukocyte antigen class I antigen processing pathway via interacting with a silencer23
CLINICAL AND TRANSLATIONAL MEDICINE23
Single‐nucleus transcriptomic profiling reveals temporal dynamics of neuroinflammation and myelin repair after intracerebral haemorrhage23
Asymmetric bilayer dressings with spatiotemporal sequence loaded with IL‐24 and GCDs for the treatment of diabetic wounds23
Single‐cell isogrowth profiling: Uniform inhibition uncovers non‐uniform drug responses23
LEPRE1 shapes a non‐flamed tumour immune landscape and predicts the prognosis in esophageal squamous cell carcinoma23
Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption23
Single‐cell RNA sequencing in exploring the pathogenesis of diabetic retinopathy23
Histone lactylation‐mediated up‐regulation of IGF2BP2 enhances ferroptosis resistance via Nrf2 in colorectal cancer23
Correction to“Splicing factor arginine/serine‐rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome‐based cellular communication”23
Transcriptomic atlas of GNAT family members in pulmonary epithelia under pathological conditions using single‐cell and bulk cell sequencing23
Soluble IL‐2R: A potential therapeutic target for mitochondrial dysfunction in post‐COVID fatigue syndrome23
Titin gene mutations enhance radiotherapy efficacy via modulation of tumour immune microenvironment in rectum adenocarcinoma23
The antiprotease Spink7 promotes inflammation resolution by modulating multiple proteases activities during wound healing23
Early molecular changes predict cancer cachexia in LKB1‐deleted mouse models of NSCLC23
Identification of hepatitis B virus infection and integration and its oncogenic role in gastric cancer22
N6‐methyladenosine‐modified circTEAD1 stabilizes Yap1 mRNA to promote chordoma tumorigenesis22
Evolution of aberrant brain‐wide spatiotemporal dynamics of resting‐state networks in a Huntington's disease mouse model22
Single‐molecule epiallelic profiling of DNA derived from routinely collected Pap specimens for noninvasive detection of ovarian cancer22
Prognosis‐oriented molecular subtypes of retroperitoneal liposarcoma22
Mitochondrial general control of amino acid synthesis 5 like 1 promotes nonalcoholic steatohepatitis development through ferroptosis‐induced formation of neutrophil extracellular traps22
Integration of single‐cell and bulk RNA sequencing unravels metalloendopeptidase+ neutrophils as key inflammatory drivers in abdominal aortic aneurysm22
Comparative spatial transcriptomics of pancreatic cancer with ductal and acinar origins in mouse models22
P301S‐hTau acetylates KEAP1 to trigger synaptic toxicity via inhibiting NRF2/ARE pathway: A novel mechanism underlying hTau‐induced synaptic toxicities22
Dissecting the cell of origin of aberrant SALL4 expression in myelodysplastic syndrome22
KMT2C/D mutations in newly diagnosed acute myeloid leukaemia: Clinical features, genetic co‐occurrences and prognostic significance22
The co‐location of CD14+APOE+ cells and MMP7+ tumour cells contributed to worse immunotherapy response in non‐small cell lung cancer22
Immune cell subset profiling and metabolic dysregulation define the divergent immune microenvironments in HIV immunological non‐responders22
Advanced mutant receptor activator of nuclear factor kappa‐Β ligand development with low affinity for osteoprotegerin22
lncRNA IGF2‐AS regulates miR‐500a‐3p/PPP4R1/p‐VEGFR2 signalling pathway to promote thyroid carcinoma progression and tubulogenesis22
One step forward for nanopore protein sequencing22
Rictor/mTORC2 signalling contributes to renal vascular endothelial‐to‐mesenchymal transition and renal allograft interstitial fibrosis by regulating BNIP3‐mediated mitophagy22
Distinct discrepancy in breast cancer organoids recapitulation among molecular subtypes revealed by single‐cell transcriptomes analysis22
MiR‐192‐5p/RB1/NF‐κBp65 signaling axis promotes IL‐10 secretion during gastric cancer EMT to induce Treg cell differentiation in the tumour microenvironment22
A novel integrated miRNA–donor age signature enables detection of cardiac allograft vasculopathy22
Synthetic lethality in cancer therapy: Mechanisms, models and clinical translation for overcoming therapeutic resistance21
Beyond bacterial defences: the role of lysozyme in cancer21
Decoding of exosome heterogeneity for cancer theranostics21
Crosstalk between alternative splicing and inflammatory bowel disease: Basic mechanisms, biotechnological progresses and future perspectives21
Atg7 in CD4+ T cells improves intestinal mucosal inflammation by regulating Ets1‐mediated T cell differentiation21
Decoding innate lymphoid cell heterogeneity and plasticity in colorectal cancer21
Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity21
Single‐cell landscape of the tumour immune microenvironment in human gynaecologic malignancies20
Intestinal Fut2 deficiency exacerbated alcohol‐related liver disease by disrupting nicotinamide metabolism20
20
CLINICAL AND TRANSLATIONAL MEDICINE20
Advances in gene therapy for Lafora disease: Intravenous recombinant adeno‐associated virus‐mediated delivery of EPM2A and EPM2B20
Liquid biopsy biomarkers for early detection of gastrointestinal cancers: Current landscape and emerging technologies20
Circulating cell‐free messenger RNA enables non‐invasive pan‐tumour monitoring of melanoma therapy independent of the mutational genotype20
20
Multiplexed plasma protein classifiers for the diagnosis of age‐related macular degeneration20
CD44v6 chimeric antigen receptor T cell specificity towards AML with FLT3 or DNMT3A mutations20
Loss of Brd4 alleviates pathological bone loss via Slc9b2 suppression in osteoclastogenesis20
20
Single‐cell RNA sequencing reveals localized tumour ablation and intratumoural immunostimulant delivery potentiate T cell mediated tumour killing20
Prediction of clinical risk assessment and survival in chronic obstructive pulmonary disease with pulmonary hypertension20
0.11414504051208