OOIR: Observatory of International Research

Papers

(The TQCC of Clinical and Translational Medicine is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
	878
Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancer	311
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells	216
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma	177
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia	150
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1–Wnt/β‐catenin–TFE3 feedback loop signalling	145
Effect of epigenetic treatment on SST₂ expression in neuroendocrine tumour patients	140
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation	131
The deubiquitinase OTUD3 plays a neuroprotective role by reducing ferroptosis induced by cerebral ischaemia reperfusion via stabilizing PLK1 via deubiquitination	118
Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer	115
Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma	113
Multi‐omics analysis revealed biomarkers for coronary atherosclerosis: Occurrence and development	111
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC	108
Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation	106
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway	105
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma	101
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca²⁺ signalling	98
HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC	93
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing	84
Glucosamine regulates macrophage function in heart failure	83
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor	82
Sendotypes predict worsening renal function in chronic kidney disease patients	82
Faecal zonulin, calprotectin and the infant microbiome in early life	74
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design	74
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma	74

Predictive medicine in a testis trio‐family through a combined multi‐omics approach	71
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases	70
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases	69
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients	68
	67
Clinical translation potential of self‐inspired live‐cell super‐resolution microscopy	65
The novel role of circular RNA ST3GAL6 on blocking gastric cancer malignant behaviours through autophagy regulated by the FOXP2/MET/mTOR axis	63
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives	63
MicroRNAs affecting the susceptibility of melanoma cells to CD8⁺ T cell‐mediated cytolysis	63
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease	62
Mitochondrial and immune response dysregulation in melanoma recurrence	61
The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease	59
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging	58
Lipids and genes: Regulatory roles of lipids in RNA expression	58
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target	58
Deciphering the secret codes in N⁷‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases	57
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma	57
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways	56
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma	56
Seize the engine: Emerging cell cycle targets in breast cancer	56
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma	54
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA	54
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis	54
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome	54
Nanopore sequencing with T2T‐CHM13 for accurate detection and preventing the transmission of structural rearrangements in highly repetitive heterochromatin regions in human embryos	52
	52
Inhibition of autophagy antagonizes breast cancer brain metastogenesis and augments the anticancer activity of lapatinib	50
NDP‐β‐d‐manno‐heptoses are small molecule agonists sensed by the vertebrates to discriminate organisms of different kingdoms	49
Pericardial delta like non‐canonical NOTCH ligand 1 (Dlk1) augments fibrosis in the heart through epithelial to mesenchymal transition	48
Suicide among patients with cancer: a call to action for researchers and clinical caregivers	47
Nano‐optogenetic immunotherapy	47
Clinical medicine journals lag behind science journals with regards to “microbiota sequence” data availability	46
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of ^AGTR1+CAFs in intrahepatic cholangiocarcinoma	46
Synergistic inhibition of progesterone receptor‐A/B signalling by simvastatin and mifepristone in human uterine leiomyomas	45
OXA1L deficiency causes mitochondrial myopathy via reactive oxygen species regulated nuclear factor kappa B signalling pathway	45
Integrated multi‐omics data reveals the molecular subtypes and guides the androgen receptor signalling inhibitor treatment of prostate cancer	45
Multi‐omics molecular phenotyping reveals the potential mechanisms of chemotherapy response and resistance in small cell lung cancer	45
	43
The genomic and transcriptomic landscapes of clock genes reveal the significance of circadian rhythm in the progression and immune microenvironment of metastatic colorectal cancer	42
Identification of the c‐Jun/H19/miR‐19/JNK1 cascade during hepatic stellate cell activation	42
Genomic classification of intrapulmonary metastasis and multiple primary lung cancer	42
Inhibition of proteasomal deubiquitinases USP14 and UCHL5 overcomes tyrosine kinase inhibitor resistance in chronic myeloid leukaemia	42
Plasma tsRNAs as novel diagnostic biomarkers for renal cell carcinoma	42
Predicted early fusion intermediates in the spike of ACE2‐utilising bat coronavirus unveil broad‐spectrum antiviral mechanisms	42
Major cell types in the coronary thrombosis of acute myocardial infarction patients revealed by scRNA‐seq	42
Role of the FOXM1/CMA/ER stress axis in regulating the progression of nonalcoholic steatohepatitis	42
Dynamics of the intratumoural microbiome across malignant transformation and treatment in breast cancer	40
Blockade of V‐domain immunoglobulin suppressor of T‐cell activation reprograms tumour‐associated macrophages and improves efficacy of PD‐1 inhibitor in gastric cancer	40
Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer	40
Translational inhalable extracellular vesicle‐based mRNA therapy for the treatment of lung cancer	40

Bmi‐1‐RING1B prevents GATA4‐dependent senescence‐associated pathological cardiac hypertrophy by promoting autophagic degradation of GATA4	39
KDM6A promotes hepatocellular carcinoma progression and dictates lenvatinib efficacy by upregulating FGFR4 expression	38
GPR65 promotes intestinal mucosal Th1 and Th17 cell differentiation and gut inflammation through downregulating NUAK2	38
PIM1 genetic alterations associated with distinct molecular profiles, phenotypes and drug responses in diffuse large B‐cell lymphoma	38
Unlocking the potential of T‐cell metabolism reprogramming: Advancing single‐cell approaches for precision immunotherapy in tumour immunity	38
The N6‐methyladenosine modification enhances ferroptosis resistance through inhibiting SLC7A11 mRNA deadenylation in hepatoblastoma	37
Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer‐associated fibroblasts	37
Unmasking the tumourigenic role of SIN1/MAPKAP1 in the mTOR complex 2	37
Disproportional enrichment of FoxP3⁺CD4⁺ regulatory T cells shapes a suppressive tumour microenvironment in head and neck squamous cell carcinoma	37
The m⁵C methyltransferase NSUN2 promotes codon‐dependent oncogenic translation by stabilising tRNA in anaplastic thyroid cancer	37
Efficacy and safety of pyrotinib combined with albumin‐bound paclitaxel as first‐line treatment for HER2‐positive metastatic breast cancer in patients previously treated with adjuvant and/or neoadjuva	36
Long‐term survival and association of neoadjuvant chemotherapy with or without immunotherapy in resectable esophageal squamous cell carcinoma	36
The role of cell‐penetrating peptides in potential anti‐cancer therapy	36
In vitro reconstitution of SPO11‐mediated DNA cleavage reveals mechanistic and clinical insights into meiotic DNA double‐strand break formation	36
WDR62 variants contribute to congenital heart disease by inhibiting cardiomyocyte proliferation	35
Severe dengue in children associates with dysregulation of lipid homeostasis, complement cascade and retinol transport	35
Transcriptomic analysis for the retested positive COVID‐19 patients with long‐term persistent SARS‐CoV‐2 but without symptoms in Wuhan	35
Microbial and human transcriptome in vaginal fluid at midgestation: Association with spontaneous preterm delivery	35
Combination anti‐HIV antibodies to achieve antiretroviral therapy‐free virological suppression in infected individuals	35
Vitamin D receptor activation in microglia suppresses NOX2‐mediated oxidative damage via PAT1 in vitro and in vivo	35
Illuminating spatial pharmacology with in situ drug imaging	35
Identification of hypoxic macrophages in glioblastoma: Unveiling therapeutic insights from tumour microenvironment analysis	34
17‐β‐estradiol reduces surface PD‐L1 expression in estrogen receptor‐positive breast cancer but not type 1 endometrial cancer cells	34
Evaluation of on‐ and off‐target effects of self‐assembled epidermal growth factor receptor small interfering RNA delivery system	34
Inhibition of KDM4C/c‐Myc/LDHA signalling axis suppresses prostate cancer metastasis via interference of glycolytic metabolism	33
In a search of a protective titer: Do we or do we not need to know?	33
Spatial‒temporal heterogeneities of liver cancer and the discovery of the invasive zone	33
Natural killer cell engagers: From bi‐specific to tri‐specific and tetra‐specific engagers for enhanced cancer immunotherapy	33
Transcriptomic evidence of lung repair in paediatric ARDS survival	33
Therapeutic targeting of CNBP phase separation inhibits ribosome biogenesis and neuroblastoma progression via modulating SWI/SNF complex activity	33
The role of long non‐coding RNAs in lung cancer metastasis: Molecular mechanisms, pathogenesis and clinical implications	33
Ubiquitous regulation of cerebrovascular diseases by ubiquitin‐modifying enzymes	32
Gene signature related to cancer stem cells and fibroblasts of stem‐like gastric cancer predicts immunotherapy response	32
m6A hypomethylation of DNMT3B regulated by ALKBH5 promotes intervertebral disc degeneration via E4F1 deficiency	32
Transcriptomic profiling reveals the dynamics of fibrotic progression‐related gene expression into post‐coronavirus disease 2019 pulmonary fibrosis	32
Interventional‐ and amputation‐stage muscle proteomes in the chronically threatened ischemic limb	32
Single‐cell sequencing of multi‐region resolves geospatial architecture and therapeutic target of endothelial cells in esophageal squamous cell carcinoma	32
The central role of a two‐way positive feedback pathway in molecular targeted therapies‐mediated pyroptosis in anaplastic thyroid cancer	32
Single‐cell RNA sequencing reveals cellular and molecular reprograming landscape of gliomas and lung cancer brain metastases	32
A randomized, double‐blind phase 1b study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of the NLRP3 inhibitor selnoflast in patients with moderate to severe active ulcera	32
Therapeutic targeting of SPIB/SPI1‐facilitated interplay of cancer cells and neutrophils inhibits aerobic glycolysis and cancer progression	32
	31
Pathogen sharing in the digital age: The unfinished agenda of the WHO pandemic agreement	31
A standardised hERG phenotyping pipeline to evaluate KCNH2 genetic variant pathogenicity	31
Involvement of MST1/mTORC1/STAT1 activity in the regulation of B‐cell receptor signalling by chemokine receptor 2	31
Cellular dynamics in tumour microenvironment along with lung cancer progression underscore spatial and evolutionary heterogeneity of neutrophil	31
Brain cholesterol therapy for Huntington's disease – Does it make sense?	31
Human mesenchymal stem‐derived extracellular vesicles improve body growth and motor function following severe spinal cord injury in rat	31
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Downregulation of SENP1 impairs nuclear condensation of MEF2C and deteriorates ischemic cardiomyopathy	30
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	30
Gestational weight gain in pregnant women with obesity is associated with cord blood DNA methylation, which partially mediates offspring anthropometrics	30
Phosphoproteomics profiling reveals a kinase network conferring acute myeloid leukaemia intrinsic chemoresistance and indicates HMGA1 phosphorylation as a potential influencer	29
Biological significance of MYC and CEBPD coamplification in urothelial carcinoma: Multilayered genomic, transcriptional and posttranscriptional positive feedback loops enhance oncogenic	29
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple‐negative breast cancer progression via an m6A‐dependent manner	29
TRIM28 attenuates Bortezomib sensitivity of hepatocellular carcinoma cells through enhanced proteasome expression	29
The potential of gas plasma technology for targeting breast cancer	29
Oncogenic PIK3CA recruits myeloid‐derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5‐lipoxygenase‐dependent arachidonic acid pathway	28
Metastasis ability, genomic profile, subtype characteristic and curative efficacy of multiple pulmonary hematogenous metastases in lung cancer	28
	28
Multi‐omics analysis of pyroptosis‐related genes for prognosis and immune landscape in head and neck cancer	28
BRAF^V600E‐PROTAC versus inhibitors in melanoma cells: Deep transcriptomic characterization	28
Lysophosphatidylcholine inhibits lung cancer cell proliferation by regulating fatty acid metabolism enzyme long‐chain acyl‐coenzyme A synthase 5	28
Managing noradrenaline after traumatic brain injury	28
CRBN is downregulated in lung cancer and negatively regulates TLR2, 4 and 7 stimulation in lung cancer cells	28
Gene therapy for Whiskott–Aldrich syndrome: The latest news	27
SMYD2‐mediated TRAF2 methylation promotes the NF‐κB signaling pathways in inflammatory diseases	27
How the brain produces generalized fear	27
Single‐cell and bulk characterisation of the distinct immune landscape and possible regulatory mechanisms in coronary plaques vulnerability	27
T‐cell differentiation stage block bias confers hypermethylation and mediastinal preference in T‐cell lymphoblastic lymphoma	27
Dynamic alterations of ctDNA associate with the therapeutic outcome in the advanced non‐small cell lung cancer patients who received sintilimab plus anlotinib regime as 1st line therapy	27
A novel role for interleukin 32 in cholestasis	27
Human‐host transcriptomic analysis reveals unique early innate immune responses in different sub‐phenotypes of COVID‐19	27
Neuronal loss drives differentially expressed protein‐pathways in the PSP globus pallidus	27
Targeting the MDK/c‐Myc complex to overcome temozolomide resistance in glioma	26
Single‐nucleus and spatial transcriptomics of paediatric ovary: Molecular insights into the dysregulated signalling pathways underlying premature ovarian insufficiency in classic galactosemia	26
Hepatic interleukin‐1 receptor type 1 signalling regulates insulin sensitivity in the early phases of nonalcoholic fatty liver disease	26
Integrated multi‐omics profiling landscape of organising pneumonia	26
SAA1 and metabolomic signatures predict hyperprogression with immunotherapy in pan cancers	26

Evaluation of pulmonary single‐cell identity specificity in scRNA‐seq analysis	26
RNA interference therapy for targeting ANGPTL3 and atherogenic lipoproteins: Findings and implications of a recent phase I study	26
Ensemble biomarkers for guiding anti‐angiogenesis therapy for ovarian cancer using deep learning	26
RAB2A promotes cervical cancer progression as revealed by comprehensive analysis of HPV integration and proteome in longitudinal cervical samples	26
Crosstalk between m6A modification and alternative splicing during cancer progression	25
OTUB1 inhibits breast cancer by non‐canonically stabilizing CCN6	25
Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies	25
Novel deep learning radiomics model for preoperative evaluation of hepatocellular carcinoma differentiation based on computed tomography data	25
Circular RNA LIPH promotes pancreatic cancer glycolysis and progression through sponge miR‐769‐3p and interaction with GOLM1	25
Single‐cell RNA‐seq reveals clonal diversity and prognostic genes of relapsed multiple myeloma	25
Human umbilical cord mesenchymal stem cells therapy alleviates kidney injury and podocyte apoptosis in Col4a5 knockout male mice	25
Targeting c‐Myc enhances immunotherapy efficacy in combination with Ras inhibitor in triple‐negative breast cancer	25
Sphingosine 1‐phosphate lyase facilitates cancer progression through converting sphingolipids to glycerophospholipids	25
Tumour organoids and assembloids: Patient‐derived cancer avatars for immunotherapy	25
Diagnostic and therapeutic potential of tonic gamma‐aminobutyric acid from reactive astrocytes in brain diseases	24
Correction to VEGF‐C/VEGFR‐3 axis protects against pressure‐overload‐induced cardiac dysfunction through regulation of lymphangiogenesis	24
Clinical predictive factors and prediction models for end‐stage renal disease in Chinese patients with type 2 diabetes mellitus	24
Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption	24
Interleukin‐2/anti‐interleukin‐2 immune complex attenuates cold ischemia‐reperfusion injury after kidney transplantation by increasing renal regulatory T cells	24
The antiprotease Spink7 promotes inflammation resolution by modulating multiple proteases activities during wound healing	24
Identification of growth hormone receptor as a relevant target for precision medicine in low‐EGFR expressing glioblastoma	24
Evaluation of vaccine effectiveness against SARS‐CoV‐2 variants by serological epitope profiling	24
Integrated mPD‐L1 and metabolic analysis identifies new prognostic subgroups in lung cancers with wild‐type EGFR	24
Issue Information	24
Issue Information	24
Hypoxia‐induced PGK1 expression promotes esophageal squamous cell carcinoma progression via stimulating MYH9‐mediated GSK3β/β‐catenin signalling	24
Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts	24
Metabolomics signature as a survival predictor in patients with resectable colorectal liver metastasis	24
Itaconate suppresses neonatal intestinal inflammation via metabolic reprogramming of M1 macrophage	23
Spliceosomal profiling identifies EIF4A3 as a novel oncogene in hepatocellular carcinoma acting through the modulation of FGFR4 splicing	23
Titin gene mutations enhance radiotherapy efficacy via modulation of tumour immune microenvironment in rectum adenocarcinoma	23
Single‐cell transcriptome analysis reveals functional changes in tumour‐infiltrating B lymphocytes after chemotherapy in oesophageal squamous cell carcinoma	23
Understanding Omicron: Transmissibility, immune evasion and antiviral intervention	23
Advancing standards in biomedical image analysis validation: A perspective on Metrics Reloaded	23
Machine learning‐based multi‐omics models for diagnostic classification and risk stratification in diabetic kidney disease	23
The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia	23
Smad3‐mediated lncRNA HSALR1 enhances the non‐classic signalling pathway of TGF‐β1 in human bronchial fibroblasts by binding to HSP90AB1	23
PI3K‐α/mTOR/BRD4 inhibitor alone or in combination with other anti‐virals blocks replication of SARS‐CoV‐2 and its variants of concern including Delta and Omicron	23
Mutations of epigenetic genes and correlation with treatment response in peripheral T‐cell lymphoma	22
Histone methyltransferase Smyd2 contributes to blood‐brain barrier breakdown in stroke	22
How the environment shapes our ability to navigate	22
Single‐cell RNA sequencing in exploring the pathogenesis of diabetic retinopathy	22
Interleukin‐11 promotes lung adenocarcinoma tumourigenesis and immune evasion	22
Small molecule Z363 co‐regulates TAF10 and MYC via the E3 ligase TRIP12 to suppress tumour growth	22
RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner	22
Translational potential of human brain charts	22
CDK7 inhibition promotes glioblastoma cell death through convergent transcriptional and metabolic stress pathways	22
YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2	22
MiRNA‐501‐3p and MiRNA‐502‐3p: A promising biomarker panel for Alzheimer's disease	22
Glutamate as a therapeutic strategy to promote liver regeneration	22
Human gut‐associated lymphoid tissue: A dynamic hub propagating modulators of inflammation	22
Snai2‐mediated upregulation of NADSYN1 promotes bladder cancer progression by interacting with PHB	22
CircSpna2 attenuates cuproptosis by mediating ubiquitin ligase Keap1 to regulate the Nrf2‐Atp7b signalling axis in depression after traumatic brain injury in a mouse model	22
Urinary DNA methylation‐based risk stratification model to triage patients for repeat transurethral resection of bladder tumours	21
Synthetic molecular sensors based on CRISPR‐Cas9 redirect anticancer signal flows to treat retinoblastomas	21
Asymmetric bilayer dressings with spatiotemporal sequence loaded with IL‐24 and GCDs for the treatment of diabetic wounds	21
KMT2C/D mutations in newly diagnosed acute myeloid leukaemia: Clinical features, genetic co‐occurrences and prognostic significance	21
Issue Information	21
Unconventional microRNA role: Enhancing the human leukocyte antigen class I antigen processing pathway via interacting with a silencer	21
Targeting transforming growth factor‐ß signalling for cancer prevention and intervention: Recent advances in developing small molecules of natural origin	21
Two 18‐norspirostane steroidal saponins as novel mitophagy enhancers improve Alzheimer's disease	21
lncRNA IGF2‐AS regulates miR‐500a‐3p/PPP4R1/p‐VEGFR2 signalling pathway to promote thyroid carcinoma progression and tubulogenesis	21
Correction to“Splicing factor arginine/serine‐rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome‐based cellular communication”	21
Single‐cell isogrowth profiling: Uniform inhibition uncovers non‐uniform drug responses	21
Integration of single‐cell and bulk RNA sequencing unravels metalloendopeptidase+ neutrophils as key inflammatory drivers in abdominal aortic aneurysm	21
Single‐nucleus transcriptomic profiling reveals temporal dynamics of neuroinflammation and myelin repair after intracerebral haemorrhage	21
	21
Early molecular changes predict cancer cachexia in LKB1‐deleted mouse models of NSCLC	21
One step forward for nanopore protein sequencing	21
Transcriptomic atlas of GNAT family members in pulmonary epithelia under pathological conditions using single‐cell and bulk cell sequencing	21
Preparation for the challenge of heavily mutated Omicron variant	20
Decoding of exosome heterogeneity for cancer theranostics	20
LEPRE1 shapes a non‐flamed tumour immune landscape and predicts the prognosis in esophageal squamous cell carcinoma	20
P301S‐hTau acetylates KEAP1 to trigger synaptic toxicity via inhibiting NRF2/ARE pathway: A novel mechanism underlying hTau‐induced synaptic toxicities	20
IGF2BP2 binding to CPSF6 facilitates m6A‐mediated alternative polyadenylation of PUM2 and promotes malignant progression in ovarian cancer	20
The co‐location of CD14+APOE+ cells and MMP7+ tumour cells contributed to worse immunotherapy response in non‐small cell lung cancer	20
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Circulating cell‐free messenger RNA enables non‐invasive pan‐tumour monitoring of melanoma therapy independent of the mutational genotype	20
Leukemia inhibitory factor receptor homodimerization mediated by acetylation of extracellular lysine promotes prostate cancer progression through the PDPK1/AKT/GCN5 axis	20
Prognosis‐oriented molecular subtypes of retroperitoneal liposarcoma	20
Identification of hepatitis B virus infection and integration and its oncogenic role in gastric cancer	19
Intestinal Fut2 deficiency exacerbated alcohol‐related liver disease by disrupting nicotinamide metabolism	19
Distinct discrepancy in breast cancer organoids recapitulation among molecular subtypes revealed by single‐cell transcriptomes analysis	19
Loss of Brd4 alleviates pathological bone loss via Slc9b2 suppression in osteoclastogenesis	19
Three‐dimensional genome structure shapes the recombination landscape of chromatin features during female germline stem cell development	19
Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double‐blind, place	19
N6‐methyladenosine‐modified circTEAD1 stabilizes Yap1 mRNA to promote chordoma tumorigenesis	19
Single‐molecule epiallelic profiling of DNA derived from routinely collected Pap specimens for noninvasive detection of ovarian cancer	19
Melatonin enhances osteoblastogenesis of senescent bone marrow stromal cells through NSD2‐mediated chromatin remodelling	19
Immune cell subset profiling and metabolic dysregulation define the divergent immune microenvironments in HIV immunological non‐responders	19
Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity	19
Comparative spatial transcriptomics of pancreatic cancer with ductal and acinar origins in mouse models	19
Atg7 in CD4⁺ T cells improves intestinal mucosal inflammation by regulating Ets1‐mediated T cell differentiation	19
MiR‐192‐5p/RB1/NF‐κBp65 signaling axis promotes IL‐10 secretion during gastric cancer EMT to induce Treg cell differentiation in the tumour microenvironment	19
Soluble IL‐2R: A potential therapeutic target for mitochondrial dysfunction in post‐COVID fatigue syndrome	19