OOIR: Observatory of International Research

Papers

(The TQCC of Clinical and Translational Medicine is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
	789
	285
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways	188
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design	157
Seize the engine: Emerging cell cycle targets in breast cancer	144
Predictive medicine in a testis trio‐family through a combined multi‐omics approach	144
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases	141
Sendotypes predict worsening renal function in chronic kidney disease patients	132
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma	122
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor	113
Faecal zonulin, calprotectin and the infant microbiome in early life	108
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma	107
The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease	105
Glucosamine regulates macrophage function in heart failure	104
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients	95
Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation	94
Lipids and genes: Regulatory roles of lipids in RNA expression	93
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives	91
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway	81
Effect of epigenetic treatment on SST₂ expression in neuroendocrine tumour patients	80
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging	80
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma	79
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells	79
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca²⁺ signalling	72
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease	68

HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC	67
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing	66
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma	66
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia	64
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC	63
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation	61
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1–Wnt/β‐catenin–TFE3 feedback loop signalling	60
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma	60
MicroRNAs affecting the susceptibility of melanoma cells to CD8⁺ T cell‐mediated cytolysis	60
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome	60
Deciphering the secret codes in N⁷‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases	60
Clinical translation potential of self‐inspired live‐cell super‐resolution microscopy	58
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis	56
The deubiquitinase OTUD3 plays a neuroprotective role by reducing ferroptosis induced by cerebral ischaemia reperfusion via stabilizing PLK1 via deubiquitination	55
Mitochondrial and immune response dysregulation in melanoma recurrence	55
Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma	54
Multi‐omics analysis revealed biomarkers for coronary atherosclerosis: Occurrence and development	54
Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancer	53
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target	53
Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer	52
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases	52
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma	52
PIM1 genetic alterations associated with distinct molecular profiles, phenotypes and drug responses in diffuse large B‐cell lymphoma	51
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA	51
Unlocking the potential of T‐cell metabolism reprogramming: Advancing single‐cell approaches for precision immunotherapy in tumour immunity	51
The novel role of circular RNA ST3GAL6 on blocking gastric cancer malignant behaviours through autophagy regulated by the FOXP2/MET/mTOR axis	51
	51
Plasma tsRNAs as novel diagnostic biomarkers for renal cell carcinoma	49
GPR65 promotes intestinal mucosal Th1 and Th17 cell differentiation and gut inflammation through downregulating NUAK2	49
Nanopore sequencing with T2T‐CHM13 for accurate detection and preventing the transmission of structural rearrangements in highly repetitive heterochromatin regions in human embryos	48
	47
Histone demethylase JMJD1C promotes the polarization of M1 macrophages to prevent glioma by upregulating miR‐302a	46
Role of the FOXM1/CMA/ER stress axis in regulating the progression of nonalcoholic steatohepatitis	45
Translational inhalable extracellular vesicle‐based mRNA therapy for the treatment of lung cancer	43
Major cell types in the coronary thrombosis of acute myocardial infarction patients revealed by scRNA‐seq	43
Suicide among patients with cancer: a call to action for researchers and clinical caregivers	42
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of ^AGTR1+CAFs in intrahepatic cholangiocarcinoma	42
Nano‐optogenetic immunotherapy	42
Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer‐associated fibroblasts	42
Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer	42
Blockade of V‐domain immunoglobulin suppressor of T‐cell activation reprograms tumour‐associated macrophages and improves efficacy of PD‐1 inhibitor in gastric cancer	41
MYTH: An algorithm to score intratumour heterogeneity based on alterations of DNA methylation profiles	41
Integrated multi‐omics data reveals the molecular subtypes and guides the androgen receptor signalling inhibitor treatment of prostate cancer	41
Inhibition of autophagy antagonizes breast cancer brain metastogenesis and augments the anticancer activity of lapatinib	41
Clinical medicine journals lag behind science journals with regards to “microbiota sequence” data availability	41
Multi‐omics molecular phenotyping reveals the potential mechanisms of chemotherapy response and resistance in small cell lung cancer	40
Synergistic inhibition of progesterone receptor‐A/B signalling by simvastatin and mifepristone in human uterine leiomyomas	40
OXA1L deficiency causes mitochondrial myopathy via reactive oxygen species regulated nuclear factor kappa B signalling pathway	38
Unmasking the tumourigenic role of SIN1/MAPKAP1 in the mTOR complex 2	37
The role of cell‐penetrating peptides in potential anti‐cancer therapy	37

NDP‐β‐d‐manno‐heptoses are small molecule agonists sensed by the vertebrates to discriminate organisms of different kingdoms	37
Pericardial delta like non‐canonical NOTCH ligand 1 (Dlk1) augments fibrosis in the heart through epithelial to mesenchymal transition	37
Inhibition of proteasomal deubiquitinases USP14 and UCHL5 overcomes tyrosine kinase inhibitor resistance in chronic myeloid leukaemia	37
The N6‐methyladenosine modification enhances ferroptosis resistance through inhibiting SLC7A11 mRNA deadenylation in hepatoblastoma	36
Identification of the c‐Jun/H19/miR‐19/JNK1 cascade during hepatic stellate cell activation	36
Genomic classification of intrapulmonary metastasis and multiple primary lung cancer	36
Disproportional enrichment of FoxP3⁺CD4⁺ regulatory T cells shapes a suppressive tumour microenvironment in head and neck squamous cell carcinoma	36
KDM6A promotes hepatocellular carcinoma progression and dictates lenvatinib efficacy by upregulating FGFR4 expression	36
The genomic and transcriptomic landscapes of clock genes reveal the significance of circadian rhythm in the progression and immune microenvironment of metastatic colorectal cancer	36
The m⁵C methyltransferase NSUN2 promotes codon‐dependent oncogenic translation by stabilising tRNA in anaplastic thyroid cancer	36
Biological significance of MYC and CEBPD coamplification in urothelial carcinoma: Multilayered genomic, transcriptional and posttranscriptional positive feedback loops enhance oncogenic	35
Bmi‐1‐RING1B prevents GATA4‐dependent senescence‐associated pathological cardiac hypertrophy by promoting autophagic degradation of GATA4	35
Identification of hypoxic macrophages in glioblastoma: Unveiling therapeutic insights from tumour microenvironment analysis	34
Single‐cell sequencing of multi‐region resolves geospatial architecture and therapeutic target of endothelial cells in esophageal squamous cell carcinoma	34
	34
	34
Efficacy and safety of pyrotinib combined with albumin‐bound paclitaxel as first‐line treatment for HER2‐positive metastatic breast cancer in patients previously treated with adjuvant and/or neoadjuva	33
Illuminating spatial pharmacology with in situ drug imaging	33
Phosphoproteomics profiling reveals a kinase network conferring acute myeloid leukaemia intrinsic chemoresistance and indicates HMGA1 phosphorylation as a potential influencer	33
Combination anti‐HIV antibodies to achieve antiretroviral therapy‐free virological suppression in infected individuals	33
	33
In vitro reconstitution of SPO11‐mediated DNA cleavage reveals mechanistic and clinical insights into meiotic DNA double‐strand break formation	33
Microbial and human transcriptome in vaginal fluid at midgestation: Association with spontaneous preterm delivery	33
Transcriptomic analysis for the retested positive COVID‐19 patients with long‐term persistent SARS‐CoV‐2 but without symptoms in Wuhan	32
Long‐term survival and association of neoadjuvant chemotherapy with or without immunotherapy in resectable esophageal squamous cell carcinoma	32
WDR62 variants contribute to congenital heart disease by inhibiting cardiomyocyte proliferation	32
Vitamin D receptor activation in microglia suppresses NOX2‐mediated oxidative damage via PAT1 in vitro and in vivo	32
Involvement of MST1/mTORC1/STAT1 activity in the regulation of B‐cell receptor signalling by chemokine receptor 2	32
Therapeutic targeting of CNBP phase separation inhibits ribosome biogenesis and neuroblastoma progression via modulating SWI/SNF complex activity	31
17‐β‐estradiol reduces surface PD‐L1 expression in estrogen receptor‐positive breast cancer but not type 1 endometrial cancer cells	31
Severe dengue in children associates with dysregulation of lipid homeostasis, complement cascade and retinol transport	31
TRIM28 attenuates Bortezomib sensitivity of hepatocellular carcinoma cells through enhanced proteasome expression	31
The prevalence and clinical implication of rare germline deleterious alterations in Chinese patients with prostate cancer: A real‐world multicenter study	31
Gestational weight gain in pregnant women with obesity is associated with cord blood DNA methylation, which partially mediates offspring anthropometrics	31
In a search of a protective titer: Do we or do we not need to know?	30
Cellular dynamics in tumour microenvironment along with lung cancer progression underscore spatial and evolutionary heterogeneity of neutrophil	30
Transcriptomic evidence of lung repair in paediatric ARDS survival	30
A standardised hERG phenotyping pipeline to evaluate KCNH2 genetic variant pathogenicity	30
Gene signature related to cancer stem cells and fibroblasts of stem‐like gastric cancer predicts immunotherapy response	30
m6A hypomethylation of DNMT3B regulated by ALKBH5 promotes intervertebral disc degeneration via E4F1 deficiency	29
Ubiquitous regulation of cerebrovascular diseases by ubiquitin‐modifying enzymes	29
Transcriptomic profiling reveals the dynamics of fibrotic progression‐related gene expression into post‐coronavirus disease 2019 pulmonary fibrosis	29
Brain cholesterol therapy for Huntington's disease – Does it make sense?	29
Spatial‒temporal heterogeneities of liver cancer and the discovery of the invasive zone	29
Evaluation of on‐ and off‐target effects of self‐assembled epidermal growth factor receptor small interfering RNA delivery system	29
Downregulation of SENP1 impairs nuclear condensation of MEF2C and deteriorates ischemic cardiomyopathy	29
Natural killer cell engagers: From bi‐specific to tri‐specific and tetra‐specific engagers for enhanced cancer immunotherapy	29
Interventional‐ and amputation‐stage muscle proteomes in the chronically threatened ischemic limb	28
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The role of long non‐coding RNAs in lung cancer metastasis: Molecular mechanisms, pathogenesis and clinical implications	28
Therapeutic targeting of SPIB/SPI1‐facilitated interplay of cancer cells and neutrophils inhibits aerobic glycolysis and cancer progression	28
Lysophosphatidylcholine inhibits lung cancer cell proliferation by regulating fatty acid metabolism enzyme long‐chain acyl‐coenzyme A synthase 5	28
A randomized, double‐blind phase 1b study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of the NLRP3 inhibitor selnoflast in patients with moderate to severe active ulcera	28
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple‐negative breast cancer progression via an m6A‐dependent manner	28
The central role of a two‐way positive feedback pathway in molecular targeted therapies‐mediated pyroptosis in anaplastic thyroid cancer	27
Single‐cell RNA sequencing reveals cellular and molecular reprograming landscape of gliomas and lung cancer brain metastases	27
Human mesenchymal stem‐derived extracellular vesicles improve body growth and motor function following severe spinal cord injury in rat	27
Oncogenic PIK3CA recruits myeloid‐derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5‐lipoxygenase‐dependent arachidonic acid pathway	27
The potential of gas plasma technology for targeting breast cancer	27
Inhibition of KDM4C/c‐Myc/LDHA signalling axis suppresses prostate cancer metastasis via interference of glycolytic metabolism	27
	26
Human‐host transcriptomic analysis reveals unique early innate immune responses in different sub‐phenotypes of COVID‐19	26
Interleukin enhancer‐binding factor 2 promotes cell proliferation and DNA damage response in metastatic melanoma	26
Integrated multi‐omics profiling landscape of organising pneumonia	26
Gene therapy for Whiskott–Aldrich syndrome: The latest news	26
Novel deep learning radiomics model for preoperative evaluation of hepatocellular carcinoma differentiation based on computed tomography data	26
SMYD2‐mediated TRAF2 methylation promotes the NF‐κB signaling pathways in inflammatory diseases	26
Single‐cell RNA‐seq reveals clonal diversity and prognostic genes of relapsed multiple myeloma	26
Dynamic alterations of ctDNA associate with the therapeutic outcome in the advanced non‐small cell lung cancer patients who received sintilimab plus anlotinib regime as 1st line therapy	26
CRBN is downregulated in lung cancer and negatively regulates TLR2, 4 and 7 stimulation in lung cancer cells	26
Neuronal loss drives differentially expressed protein‐pathways in the PSP globus pallidus	26
A novel role for interleukin 32 in cholestasis	26
Targeting the MDK/c‐Myc complex to overcome temozolomide resistance in glioma	25
BRAF^V600E‐PROTAC versus inhibitors in melanoma cells: Deep transcriptomic characterization	25
Multi‐omics analysis of pyroptosis‐related genes for prognosis and immune landscape in head and neck cancer	25
Circular RNA LIPH promotes pancreatic cancer glycolysis and progression through sponge miR‐769‐3p and interaction with GOLM1	25
Single‐nucleus and spatial transcriptomics of paediatric ovary: Molecular insights into the dysregulated signalling pathways underlying premature ovarian insufficiency in classic galactosemia	25
Tumour organoids and assembloids: Patient‐derived cancer avatars for immunotherapy	25
Managing noradrenaline after traumatic brain injury	25
Metastasis ability, genomic profile, subtype characteristic and curative efficacy of multiple pulmonary hematogenous metastases in lung cancer	25

Prognostic, clinicopathological, and immune correlation of NLRP3 promoter methylation in kidney renal clear cell carcinoma	25
Ensemble biomarkers for guiding anti‐angiogenesis therapy for ovarian cancer using deep learning	24
OTUB1 inhibits breast cancer by non‐canonically stabilizing CCN6	24
Single‐cell and bulk characterisation of the distinct immune landscape and possible regulatory mechanisms in coronary plaques vulnerability	24
SAA1 and metabolomic signatures predict hyperprogression with immunotherapy in pan cancers	24
The immune checkpoints storm in COVID‐19: Role as severity markers at emergency department admission	24
How the brain produces generalized fear	24
Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies	24
Sphingosine 1‐phosphate lyase facilitates cancer progression through converting sphingolipids to glycerophospholipids	24
RAB2A promotes cervical cancer progression as revealed by comprehensive analysis of HPV integration and proteome in longitudinal cervical samples	24
T‐cell differentiation stage block bias confers hypermethylation and mediastinal preference in T‐cell lymphoblastic lymphoma	24
RNA interference therapy for targeting ANGPTL3 and atherogenic lipoproteins: Findings and implications of a recent phase I study	24
Issue Information	23
Issue Information	23
Machine learning algorithms utilizing blood parameters enable early detection of immunethrombotic dysregulation in COVID‐19	23
Hepatic interleukin‐1 receptor type 1 signalling regulates insulin sensitivity in the early phases of nonalcoholic fatty liver disease	23
Identification of growth hormone receptor as a relevant target for precision medicine in low‐EGFR expressing glioblastoma	23
Evaluation of vaccine effectiveness against SARS‐CoV‐2 variants by serological epitope profiling	23
Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts	23
Crosstalk between m6A modification and alternative splicing during cancer progression	23
Evaluation of pulmonary single‐cell identity specificity in scRNA‐seq analysis	23
Small molecule Z363 co‐regulates TAF10 and MYC via the E3 ligase TRIP12 to suppress tumour growth	23
Translational potential of human brain charts	23
Clinical predictive factors and prediction models for end‐stage renal disease in Chinese patients with type 2 diabetes mellitus	22
Mutations of epigenetic genes and correlation with treatment response in peripheral T‐cell lymphoma	22
Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption	22
Histone methyltransferase Smyd2 contributes to blood‐brain barrier breakdown in stroke	22
The antiprotease Spink7 promotes inflammation resolution by modulating multiple proteases activities during wound healing	22
Synthetic molecular sensors based on CRISPR‐Cas9 redirect anticancer signal flows to treat retinoblastomas	22
CircSpna2 attenuates cuproptosis by mediating ubiquitin ligase Keap1 to regulate the Nrf2‐Atp7b signalling axis in depression after traumatic brain injury in a mouse model	22
Urinary DNA methylation‐based risk stratification model to triage patients for repeat transurethral resection of bladder tumours	22
PI3K‐α/mTOR/BRD4 inhibitor alone or in combination with other anti‐virals blocks replication of SARS‐CoV‐2 and its variants of concern including Delta and Omicron	22
Hypoxia‐induced PGK1 expression promotes esophageal squamous cell carcinoma progression via stimulating MYH9‐mediated GSK3β/β‐catenin signalling	22
Integrated mPD‐L1 and metabolic analysis identifies new prognostic subgroups in lung cancers with wild‐type EGFR	22
Metabolomics signature as a survival predictor in patients with resectable colorectal liver metastasis	22
Interleukin‐2/anti‐interleukin‐2 immune complex attenuates cold ischemia‐reperfusion injury after kidney transplantation by increasing renal regulatory T cells	22
Diagnostic and therapeutic potential of tonic gamma‐aminobutyric acid from reactive astrocytes in brain diseases	22
Correction to VEGF‐C/VEGFR‐3 axis protects against pressure‐overload‐induced cardiac dysfunction through regulation of lymphangiogenesis	22
Two 18‐norspirostane steroidal saponins as novel mitophagy enhancers improve Alzheimer's disease	21
Machine learning‐based multi‐omics models for diagnostic classification and risk stratification in diabetic kidney disease	21
Understanding Omicron: Transmissibility, immune evasion and antiviral intervention	21
Glutamate as a therapeutic strategy to promote liver regeneration	21
Single‐cell RNA sequencing in exploring the pathogenesis of diabetic retinopathy	21
CDK7 inhibition promotes glioblastoma cell death through convergent transcriptional and metabolic stress pathways	21
Titin gene mutations enhance radiotherapy efficacy via modulation of tumour immune microenvironment in rectum adenocarcinoma	21
MiRNA‐501‐3p and MiRNA‐502‐3p: A promising biomarker panel for Alzheimer's disease	21
The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia	21
Itaconate suppresses neonatal intestinal inflammation via metabolic reprogramming of M1 macrophage	21
Spliceosomal profiling identifies EIF4A3 as a novel oncogene in hepatocellular carcinoma acting through the modulation of FGFR4 splicing	21
Single‐cell transcriptome analysis reveals functional changes in tumour‐infiltrating B lymphocytes after chemotherapy in oesophageal squamous cell carcinoma	21
Smad3‐mediated lncRNA HSALR1 enhances the non‐classic signalling pathway of TGF‐β1 in human bronchial fibroblasts by binding to HSP90AB1	21
Human gut‐associated lymphoid tissue: A dynamic hub propagating modulators of inflammation	21
Interleukin‐11 promotes lung adenocarcinoma tumourigenesis and immune evasion	21
YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2	21
Targeting transforming growth factor‐ß signalling for cancer prevention and intervention: Recent advances in developing small molecules of natural origin	20
Crosstalk between alternative splicing and inflammatory bowel disease: Basic mechanisms, biotechnological progresses and future perspectives	20
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Snai2‐mediated upregulation of NADSYN1 promotes bladder cancer progression by interacting with PHB	20
Advancing standards in biomedical image analysis validation: A perspective on Metrics Reloaded	20
Advanced mutant receptor activator of nuclear factor kappa‐Β ligand development with low affinity for osteoprotegerin	20
How the environment shapes our ability to navigate	20
RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner	20
CD44v6 chimeric antigen receptor T cell specificity towards AML with FLT3 or DNMT3A mutations	20
Distinct discrepancy in breast cancer organoids recapitulation among molecular subtypes revealed by single‐cell transcriptomes analysis	19
Single‐cell isogrowth profiling: Uniform inhibition uncovers non‐uniform drug responses	19
KMT2C/D mutations in newly diagnosed acute myeloid leukaemia: Clinical features, genetic co‐occurrences and prognostic significance	19
Single‐molecule epiallelic profiling of DNA derived from routinely collected Pap specimens for noninvasive detection of ovarian cancer	19
Prognosis‐oriented molecular subtypes of retroperitoneal liposarcoma	19
Unconventional microRNA role: Enhancing the human leukocyte antigen class I antigen processing pathway via interacting with a silencer	19
Dissecting the cell of origin of aberrant SALL4 expression in myelodysplastic syndrome	19
Three‐dimensional genome structure shapes the recombination landscape of chromatin features during female germline stem cell development	19
The co‐location of CD14+APOE+ cells and MMP7+ tumour cells contributed to worse immunotherapy response in non‐small cell lung cancer	19
Issue Information	19
Transcriptomic atlas of GNAT family members in pulmonary epithelia under pathological conditions using single‐cell and bulk cell sequencing	19
Prediction of clinical risk assessment and survival in chronic obstructive pulmonary disease with pulmonary hypertension	19
Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity	19
Leukemia inhibitory factor receptor homodimerization mediated by acetylation of extracellular lysine promotes prostate cancer progression through the PDPK1/AKT/GCN5 axis	19
Ultrasound‐guided percutaneous metal‐organic frameworks based codelivery system of doxorubicin/acetazolamide for hepatocellular carcinoma therapy	19
GPR65, a novel regulator of helper T‐cell polarization in inflammatory bowel disease	19
Correction to“Splicing factor arginine/serine‐rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome‐based cellular communication”	19
Evolution of aberrant brain‐wide spatiotemporal dynamics of resting‐state networks in a Huntington's disease mouse model	19
One step forward for nanopore protein sequencing	19
Methionine oxidation of CLK4 promotes the metabolic switch and redox homeostasis in esophageal carcinoma via inhibiting MITF selective autophagy	19
Integration of single‐cell and bulk RNA sequencing unravels metalloendopeptidase+ neutrophils as key inflammatory drivers in abdominal aortic aneurysm	19
Preparation for the challenge of heavily mutated Omicron variant	19
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LEPRE1 shapes a non‐flamed tumour immune landscape and predicts the prognosis in esophageal squamous cell carcinoma	19
lncRNA IGF2‐AS regulates miR‐500a‐3p/PPP4R1/p‐VEGFR2 signalling pathway to promote thyroid carcinoma progression and tubulogenesis	18
P301S‐hTau acetylates KEAP1 to trigger synaptic toxicity via inhibiting NRF2/ARE pathway: A novel mechanism underlying hTau‐induced synaptic toxicities	18
Comparative spatial transcriptomics of pancreatic cancer with ductal and acinar origins in mouse models	18
Integrated microbiome, metabolome, and proteome analysis identifies a novel interplay among commensal bacteria, metabolites and candidate targets in non‐small cell lung cancer	18
Rictor/mTORC2 signalling contributes to renal vascular endothelial‐to‐mesenchymal transition and renal allograft interstitial fibrosis by regulating BNIP3‐mediated mitophagy	18
Intestinal Fut2 deficiency exacerbated alcohol‐related liver disease by disrupting nicotinamide metabolism	18
MiR‐192‐5p/RB1/NF‐κBp65 signaling axis promotes IL‐10 secretion during gastric cancer EMT to induce Treg cell differentiation in the tumour microenvironment	18
Identification of hepatitis B virus infection and integration and its oncogenic role in gastric cancer	18