Clinical and Translational Medicine

Papers
(The median citation count of Clinical and Translational Medicine is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation394
Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation332
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design153
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC147
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HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC119
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Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients109
Sendotypes predict worsening renal function in chronic kidney disease patients96
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging95
Deciphering the secret codes in N7‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases95
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway95
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma94
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells93
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease92
Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma87
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis85
MicroRNAs affecting the susceptibility of melanoma cells to CD8+ T cell‐mediated cytolysis83
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome77
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma76
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor76
Multi‐omics analysis revealed biomarkers for coronary atherosclerosis: Occurrence and development74
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia73
A droplet that releases stress: Drop‐printing for conformal bioelectronics at neural and soft‐tissue interfaces71
Macrophage Cluster of Differentiation 163 promotes post‐infarction cardiac repair and preserves left ventricular function via osteopontin70
Predictive medicine in a testis trio‐family through a combined multi‐omics approach70
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases70
The deubiquitinase OTUD3 plays a neuroprotective role by reducing ferroptosis induced by cerebral ischaemia reperfusion via stabilizing PLK1 via deubiquitination69
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma68
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing65
Illuminating the genomic frontier of invasive non‐typhoidal Salmonella infections63
Seize the engine: Emerging cell cycle targets in breast cancer61
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases60
Clinical translation potential of self‐inspired live‐cell super‐resolution microscopy60
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca2+ signalling60
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives59
Regulatory mechanism of O‐linked N‐acetylglucosamine protein modification on autophagy in cancer58
Ubc9‐mediated SUMOylation of Ninj1 alleviates inflammatory responses in hepatic ischaemia/reperfusion injury58
Quantum biology: From mechanisms to medicine58
Effect of epigenetic treatment on SST2 expression in neuroendocrine tumour patients58
Mitochondrial and immune response dysregulation in melanoma recurrence57
Targeting lysine methyltransferase 2C deficiency: New frontiers in breast cancer therapy and prognosis56
The biological burden of conflict across populations worldwide55
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma54
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target53
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma52
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways52
Faecal zonulin, calprotectin and the infant microbiome in early life51
Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer51
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma50
NDP‐βdmanno‐heptoses are small molecule agonists sensed by the vertebrates to discriminate organisms of different kingdoms49
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Suicide among patients with cancer: a call to action for researchers and clinical caregivers49
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA49
Multi‐omics molecular phenotyping reveals the potential mechanisms of chemotherapy response and resistance in small cell lung cancer48
Synergistic inhibition of progesterone receptor‐A/B signalling by simvastatin and mifepristone in human uterine leiomyomas48
Nano‐optogenetic immunotherapy47
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Major cell types in the coronary thrombosis of acute myocardial infarction patients revealed by scRNA‐seq46
Predicted early fusion intermediates in the spike of ACE2‐utilising bat coronavirus unveil broad‐spectrum antiviral mechanisms46
Genomic classification of intrapulmonary metastasis and multiple primary lung cancer46
Inhibition of autophagy antagonizes breast cancer brain metastogenesis and augments the anticancer activity of lapatinib45
Role of the FOXM1/CMA/ER stress axis in regulating the progression of nonalcoholic steatohepatitis45
Inhibition of proteasomal deubiquitinases USP14 and UCHL5 overcomes tyrosine kinase inhibitor resistance in chronic myeloid leukaemia45
Niacin promotes motor function recovery after spinal cord injury via Hcar2‐dependent microglia immunometabolic regulation45
OXA1L deficiency causes mitochondrial myopathy via reactive oxygen species regulated nuclear factor kappa B signalling pathway45
Dynamics of the intratumoural microbiome across malignant transformation and treatment in breast cancer44
Identification of the c‐Jun/H19/miR‐19/JNK1 cascade during hepatic stellate cell activation44
Translational inhalable extracellular vesicle‐based mRNA therapy for the treatment of lung cancer44
ALKBH3 suppresses ischemia/reperfusion‐induced PANoptosis by regulating the ZBED6/STAT1/AIM2 axis through m 1 A demethylation43
Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer43
Pericardial delta like non‐canonical NOTCH ligand 1 (Dlk1) augments fibrosis in the heart through epithelial to mesenchymal transition43
Fibroblast growth factor 10 attenuates advanced liver fibrosis through hepatocyte fibroblast growth factor receptor 2 signalling43
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of AGTR1+CAFs in intrahepatic cholangiocarcinoma43
CAR‐DC combined with CAR‐T therapy for relapsed/refractory acute myeloid leukaemia: Research progress and future perspectives42
Tumour‐targeted fluorescence‐guided surgery in gastrointestinal cancer: A systematic review of preclinical and clinical research42
Unlocking the potential of T‐cell metabolism reprogramming: Advancing single‐cell approaches for precision immunotherapy in tumour immunity41
Plasma tsRNAs as novel diagnostic biomarkers for renal cell carcinoma41
Unmasking the tumourigenic role of SIN1/MAPKAP1 in the mTOR complex 241
Nanopore sequencing with T2T‐CHM13 for accurate detection and preventing the transmission of structural rearrangements in highly repetitive heterochromatin regions in human embryos40
The m5C methyltransferase NSUN2 promotes codon‐dependent oncogenic translation by stabilising tRNA in anaplastic thyroid cancer39
Adipocyte fatty acid‐binding protein as a cerebrospinal fluid–accessible biomarker and druggable target in subarachnoid haemorrhage: Linking fatty acid dysregulation to microglial neuroinflammation39
Blockade of V‐domain immunoglobulin suppressor of T‐cell activation reprograms tumour‐associated macrophages and improves efficacy of PD‐1 inhibitor in gastric cancer39
KDM6A promotes hepatocellular carcinoma progression and dictates lenvatinib efficacy by upregulating FGFR4 expression39
Erratum to “Clinic‐ready inhibitor of MMP−9/−12 restores sensory and functional decline in rodent models of spinal cord injury”39
17‐β‐estradiol reduces surface PD‐L1 expression in estrogen receptor‐positive breast cancer but not type 1 endometrial cancer cells38
Combination anti‐HIV antibodies to achieve antiretroviral therapy‐free virological suppression in infected individuals38
Illuminating spatial pharmacology with in situ drug imaging38
Long‐term survival and association of neoadjuvant chemotherapy with or without immunotherapy in resectable esophageal squamous cell carcinoma38
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Transcriptomic analysis for the retested positive COVID‐19 patients with long‐term persistent SARS‐CoV‐2 but without symptoms in Wuhan38
In vitro reconstitution of SPO11‐mediated DNA cleavage reveals mechanistic and clinical insights into meiotic DNA double‐strand break formation38
The potential of gas plasma technology for targeting breast cancer37
Brain cholesterol therapy for Huntington's disease – Does it make sense?37
Involvement of MST1/mTORC1/STAT1 activity in the regulation of B‐cell receptor signalling by chemokine receptor 237
Ubiquitous regulation of cerebrovascular diseases by ubiquitin‐modifying enzymes37
Gestational weight gain in pregnant women with obesity is associated with cord blood DNA methylation, which partially mediates offspring anthropometrics37
Transcriptomic profiling reveals the dynamics of fibrotic progression‐related gene expression into post‐coronavirus disease 2019 pulmonary fibrosis36
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Pathogen sharing in the digital age: The unfinished agenda of the WHO pandemic agreement36
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Single‐cell sequencing of multi‐region resolves geospatial architecture and therapeutic target of endothelial cells in esophageal squamous cell carcinoma36
Severe dengue in children associates with dysregulation of lipid homeostasis, complement cascade and retinol transport36
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Efficacy and safety of pyrotinib combined with albumin‐bound paclitaxel as first‐line treatment for HER2‐positive metastatic breast cancer in patients previously treated with adjuvant and/or neoadjuva36
Gene signature related to cancer stem cells and fibroblasts of stem‐like gastric cancer predicts immunotherapy response35
Oncogenic PIK3CA recruits myeloid‐derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5‐lipoxygenase‐dependent arachidonic acid pathway35
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple‐negative breast cancer progression via an m6A‐dependent manner35
Cellular dynamics in tumour microenvironment along with lung cancer progression underscore spatial and evolutionary heterogeneity of neutrophil35
Natural killer cell engagers: From bi‐specific to tri‐specific and tetra‐specific engagers for enhanced cancer immunotherapy34
Transcriptomic evidence of lung repair in paediatric ARDS survival33
Single‐cell RNA sequencing reveals cellular and molecular reprograming landscape of gliomas and lung cancer brain metastases33
WDR62 variants contribute to congenital heart disease by inhibiting cardiomyocyte proliferation33
A randomized, double‐blind phase 1b study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of the NLRP3 inhibitor selnoflast in patients with moderate to severe active ulcera33
The role of long non‐coding RNAs in lung cancer metastasis: Molecular mechanisms, pathogenesis and clinical implications33
Vitamin D receptor activation in microglia suppresses NOX2‐mediated oxidative damage via PAT1 in vitro and in vivo33
Spatial‒temporal heterogeneities of liver cancer and the discovery of the invasive zone33
Downregulation of SENP1 impairs nuclear condensation of MEF2C and deteriorates ischemic cardiomyopathy33
The rise of marine fungi: Drug discovery's blue frontier32
Therapeutic targeting of CNBP phase separation inhibits ribosome biogenesis and neuroblastoma progression via modulating SWI/SNF complex activity32
Identification of hypoxic macrophages in glioblastoma: Unveiling therapeutic insights from tumour microenvironment analysis32
Human mesenchymal stem‐derived extracellular vesicles improve body growth and motor function following severe spinal cord injury in rat32
CLINICAL AND TRANSLATIONAL MEDICINE32
Lysophosphatidylcholine inhibits lung cancer cell proliferation by regulating fatty acid metabolism enzyme long‐chain acyl‐coenzyme A synthase 531
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Evaluation of on‐ and off‐target effects of self‐assembled epidermal growth factor receptor small interfering RNA delivery system31
Targeting c‐Myc enhances immunotherapy efficacy in combination with Ras inhibitor in triple‐negative breast cancer31
Microbial and human transcriptome in vaginal fluid at midgestation: Association with spontaneous preterm delivery31
Dynamic alterations of ctDNA associate with the therapeutic outcome in the advanced non‐small cell lung cancer patients who received sintilimab plus anlotinib regime as 1st line therapy30
Targeting the MDK/c‐Myc complex to overcome temozolomide resistance in glioma30
Metastasis ability, genomic profile, subtype characteristic and curative efficacy of multiple pulmonary hematogenous metastases in lung cancer30
Multi‐omics analysis of pyroptosis‐related genes for prognosis and immune landscape in head and neck cancer30
How the brain produces generalized fear30
Human umbilical cord mesenchymal stem cells therapy alleviates kidney injury and podocyte apoptosis in Col4a5 knockout male mice30
Human‐host transcriptomic analysis reveals unique early innate immune responses in different sub‐phenotypes of COVID‐1929
Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies29
Ensemble biomarkers for guiding anti‐angiogenesis therapy for ovarian cancer using deep learning29
Evaluation of pulmonary single‐cell identity specificity in scRNA‐seq analysis29
Neuronal loss drives differentially expressed protein‐pathways in the PSP globus pallidus29
OTUB1 inhibits breast cancer by non‐canonically stabilizing CCN629
Managing noradrenaline after traumatic brain injury29
P2X7R deficiency alleviates cardiac senescence by enhancing mitophagy via the HuR/TRIM26/NR4A1 axis29
Single‐nucleus and spatial transcriptomics of paediatric ovary: Molecular insights into the dysregulated signalling pathways underlying premature ovarian insufficiency in classic galactosemia29
Sphingosine 1‐phosphate lyase facilitates cancer progression through converting sphingolipids to glycerophospholipids28
SAA1 and metabolomic signatures predict hyperprogression with immunotherapy in pan cancers28
CRBN is downregulated in lung cancer and negatively regulates TLR2, 4 and 7 stimulation in lung cancer cells28
Single‐cell and bulk characterisation of the distinct immune landscape and possible regulatory mechanisms in coronary plaques vulnerability28
Hepatic interleukin‐1 receptor type 1 signalling regulates insulin sensitivity in the early phases of nonalcoholic fatty liver disease27
Spatial and single‐cell RNA sequencing reveals the immune microenvironment of human ascending thoracic aortic aneurysms27
Improving detection of colorectal cancer: A Bayesian approach to serial circulating tumour DNA testing following curative‐intent treatment.27
Tumour organoids and assembloids: Patient‐derived cancer avatars for immunotherapy27
BRAFV600E‐PROTAC versus inhibitors in melanoma cells: Deep transcriptomic characterization27
Integrated multi‐omics profiling landscape of organising pneumonia27
T‐cell differentiation stage block bias confers hypermethylation and mediastinal preference in T‐cell lymphoblastic lymphoma27
Circular RNA LIPH promotes pancreatic cancer glycolysis and progression through sponge miR‐769‐3p and interaction with GOLM127
Small molecule Z363 co‐regulates TAF10 and MYC via the E3 ligase TRIP12 to suppress tumour growth26
Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts26
Diagnostic and therapeutic potential of tonic gamma‐aminobutyric acid from reactive astrocytes in brain diseases26
Advancing standards in biomedical image analysis validation: A perspective on Metrics Reloaded26
Issue Information26
Crosstalk between m6A modification and alternative splicing during cancer progression26
Issue Information26
Evaluation of vaccine effectiveness against SARS‐CoV‐2 variants by serological epitope profiling26
Interleukin‐11 promotes lung adenocarcinoma tumourigenesis and immune evasion26
Translational potential of human brain charts26
RNA interference therapy for targeting ANGPTL3 and atherogenic lipoproteins: Findings and implications of a recent phase I study26
Correction to VEGF‐C/VEGFR‐3 axis protects against pressure‐overload‐induced cardiac dysfunction through regulation of lymphangiogenesis26
How the environment shapes our ability to navigate26
Spliceosomal profiling identifies EIF4A3 as a novel oncogene in hepatocellular carcinoma acting through the modulation of FGFR4 splicing26
Identification of growth hormone receptor as a relevant target for precision medicine in low‐EGFR expressing glioblastoma26
Titin gene mutations enhance radiotherapy efficacy via modulation of tumour immune microenvironment in rectum adenocarcinoma25
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Single‐cell RNA sequencing in exploring the pathogenesis of diabetic retinopathy25
Mutations of epigenetic genes and correlation with treatment response in peripheral T‐cell lymphoma25
The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia25
Itaconate suppresses neonatal intestinal inflammation via metabolic reprogramming of M1 macrophage25
Metabolomics signature as a survival predictor in patients with resectable colorectal liver metastasis25
Single‐nucleus transcriptomic profiling reveals temporal dynamics of neuroinflammation and myelin repair after intracerebral haemorrhage25
Glutamate as a therapeutic strategy to promote liver regeneration25
Single‐cell transcriptome analysis reveals functional changes in tumour‐infiltrating B lymphocytes after chemotherapy in oesophageal squamous cell carcinoma25
Urinary DNA methylation‐based risk stratification model to triage patients for repeat transurethral resection of bladder tumours25
TMEM92 shields DDX3X from TTC3‐mediated degradation to confer chemoresistance in triple‐negative breast cancer24
Hypoxia‐induced PGK1 expression promotes esophageal squamous cell carcinoma progression via stimulating MYH9‐mediated GSK3β/β‐catenin signalling24
Two 18‐norspirostane steroidal saponins as novel mitophagy enhancers improve Alzheimer's disease24
Machine learning‐based multi‐omics models for diagnostic classification and risk stratification in diabetic kidney disease24
RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner24
The antiprotease Spink7 promotes inflammation resolution by modulating multiple proteases activities during wound healing24
MiRNA‐501‐3p and MiRNA‐502‐3p: A promising biomarker panel for Alzheimer's disease24
Integrated multi‐regional multiomic profiling of breast phyllodes tumours reveals peritumoural immune activation and stromal remodelling24
Clinical predictive factors and prediction models for end‐stage renal disease in Chinese patients with type 2 diabetes mellitus24
Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption24
Human gut‐associated lymphoid tissue: A dynamic hub propagating modulators of inflammation24
Smad3‐mediated lncRNA HSALR1 enhances the non‐classic signalling pathway of TGF‐β1 in human bronchial fibroblasts by binding to HSP90AB124
Plasma cell‐free DNA markers predict occult metastases in patients with resectable pancreatic ductal adenocarcinoma24
CircSpna2 attenuates cuproptosis by mediating ubiquitin ligase Keap1 to regulate the Nrf2‐Atp7b signalling axis in depression after traumatic brain injury in a mouse model24
CDK7 inhibition promotes glioblastoma cell death through convergent transcriptional and metabolic stress pathways24
Systemic lupus erythematosus extends beyond a type I interferonopathy, as demonstrated by NET‐activated monocytes23
Asymmetric bilayer dressings with spatiotemporal sequence loaded with IL‐24 and GCDs for the treatment of diabetic wounds23
YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM223
HepAssis2 ® bioartificial liver system in treating acute‐on‐chronic liver failure patients: Findings from a phase 1 randomised, open‐label clinical t23
Early molecular changes predict cancer cachexia in LKB1‐deleted mouse models of NSCLC23
Snai2‐mediated upregulation of NADSYN1 promotes bladder cancer progression by interacting with PHB23
Interleukin‐2/anti‐interleukin‐2 immune complex attenuates cold ischemia‐reperfusion injury after kidney transplantation by increasing renal regulatory T cells23
Histone lactylation‐mediated up‐regulation of IGF2BP2 enhances ferroptosis resistance via Nrf2 in colorectal cancer23
GPR65, a novel regulator of helper T‐cell polarization in inflammatory bowel disease22
Transcriptomic atlas of GNAT family members in pulmonary epithelia under pathological conditions using single‐cell and bulk cell sequencing22
Unconventional microRNA role: Enhancing the human leukocyte antigen class I antigen processing pathway via interacting with a silencer22
Intestinal Fut2 deficiency exacerbated alcohol‐related liver disease by disrupting nicotinamide metabolism22
Dissecting the cell of origin of aberrant SALL4 expression in myelodysplastic syndrome22
CD44v6 chimeric antigen receptor T cell specificity towards AML with FLT3 or DNMT3A mutations22
One step forward for nanopore protein sequencing22
Correction to“Splicing factor arginine/serine‐rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome‐based cellular communication”22
LEPRE1 shapes a non‐flamed tumour immune landscape and predicts the prognosis in esophageal squamous cell carcinoma22
Single‐cell isogrowth profiling: Uniform inhibition uncovers non‐uniform drug responses22
Identification of hepatitis B virus infection and integration and its oncogenic role in gastric cancer22
Rictor/mTORC2 signalling contributes to renal vascular endothelial‐to‐mesenchymal transition and renal allograft interstitial fibrosis by regulating BNIP3‐mediated mitophagy22
Evolution of aberrant brain‐wide spatiotemporal dynamics of resting‐state networks in a Huntington's disease mouse model22
N6‐methyladenosine‐modified circTEAD1 stabilizes Yap1 mRNA to promote chordoma tumorigenesis22
Soluble IL‐2R: A potential therapeutic target for mitochondrial dysfunction in post‐COVID fatigue syndrome22
P301S‐hTau acetylates KEAP1 to trigger synaptic toxicity via inhibiting NRF2/ARE pathway: A novel mechanism underlying hTau‐induced synaptic toxicities22
Issue Information22
Loss of Brd4 alleviates pathological bone loss via Slc9b2 suppression in osteoclastogenesis22
Advanced mutant receptor activator of nuclear factor kappa‐Β ligand development with low affinity for osteoprotegerin22
Comparative spatial transcriptomics of pancreatic cancer with ductal and acinar origins in mouse models22
lncRNA IGF2‐AS regulates miR‐500a‐3p/PPP4R1/p‐VEGFR2 signalling pathway to promote thyroid carcinoma progression and tubulogenesis22
Advances in gene therapy for Lafora disease: Intravenous recombinant adeno‐associated virus‐mediated delivery of EPM2A and EPM2B21
A novel integrated miRNA–donor age signature enables detection of cardiac allograft vasculopathy21
Single‐cell landscape of the tumour immune microenvironment in human gynaecologic malignancies21
Parvimonas micra promotes carcinogenesis of colorectal cancer through phenyllactic acid‐induced DNA damage21
IGF2BP2 binding to CPSF6 facilitates m6A‐mediated alternative polyadenylation of PUM2 and promotes malignant progression in ovarian cancer21
KMT2C/D mutations in newly diagnosed acute myeloid leukaemia: Clinical features, genetic co‐occurrences and prognostic significance21
Liquid biopsy biomarkers for early detection of gastrointestinal cancers: Current landscape and emerging technologies21
Decoding of exosome heterogeneity for cancer theranostics21
Crosstalk between alternative splicing and inflammatory bowel disease: Basic mechanisms, biotechnological progresses and future perspectives21
MiR‐192‐5p/RB1/NF‐κBp65 signaling axis promotes IL‐10 secretion during gastric cancer EMT to induce Treg cell differentiation in the tumour microenvironment21
Mitochondrial general control of amino acid synthesis 5 like 1 promotes nonalcoholic steatohepatitis development through ferroptosis‐induced formation of neutrophil extracellular traps21
Three‐dimensional genome structure shapes the recombination landscape of chromatin features during female germline stem cell development21
Immune cell subset profiling and metabolic dysregulation define the divergent immune microenvironments in HIV immunological non‐responders21
Single‐molecule epiallelic profiling of DNA derived from routinely collected Pap specimens for noninvasive detection of ovarian cancer21
Atg7 in CD4+ T cells improves intestinal mucosal inflammation by regulating Ets1‐mediated T cell differentiation21
Integration of single‐cell and bulk RNA sequencing unravels metalloendopeptidase+ neutrophils as key inflammatory drivers in abdominal aortic aneurysm21
The co‐location of CD14+APOE+ cells and MMP7+ tumour cells contributed to worse immunotherapy response in non‐small cell lung cancer20
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CRISPRi screening identifies PIKfyve as a co‐therapeutic target for obinutuzumab20
Circulating cell‐free messenger RNA enables non‐invasive pan‐tumour monitoring of melanoma therapy independent of the mutational genotype20
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Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity20
Integrated microbiome, metabolome, and proteome analysis identifies a novel interplay among commensal bacteria, metabolites and candidate targets in non‐small cell lung cancer20
Prediction of clinical risk assessment and survival in chronic obstructive pulmonary disease with pulmonary hypertension20
The roles and therapeutic implications of messenger RNA internal N7‐methylguanosine and N6‐methyladenosine modifications in chemoresistance20
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