OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical and Translational Medicine is 49. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Five‐day water‐only fasting decreased metabolic‐syndrome risk factors and increased anti‐aging biomarkers without toxicity in a clinical trial of normal‐weight individuals	653
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway	228
Glucosamine regulates macrophage function in heart failure	201
Faecal zonulin, calprotectin and the infant microbiome in early life	153
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca²⁺ signalling	141
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease	140
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma	131
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging	127
Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation	127
Predictive medicine in a testis trio‐family through a combined multi‐omics approach	122
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases	111
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma	108
Effect of epigenetic treatment on SST₂ expression in neuroendocrine tumour patients	97
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma	97
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design	96
Lipids and genes: Regulatory roles of lipids in RNA expression	95
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC	95
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation	92
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor	91
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells	84
HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC	82
	80
	80
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma	77
MicroRNAs affecting the susceptibility of melanoma cells to CD8⁺ T cell‐mediated cytolysis	74

A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia	74
The novel role of circular RNA ST3GAL6 on blocking gastric cancer malignant behaviours through autophagy regulated by the FOXP2/MET/mTOR axis	73
Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation	69
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing	68
Deciphering the secret codes in N⁷‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases	68
Potential of peptide‐engineered exosomes with overexpressed miR‐92b‐3p in anti‐angiogenic therapy of ovarian cancer	63
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma	61
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases	60
Seize the engine: Emerging cell cycle targets in breast cancer	59
Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancer	56
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives	54
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma	54
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target	54
Sendotypes predict worsening renal function in chronic kidney disease patients	53
Molecular and physical technologies for monitoring fluid and electrolyte imbalance: A focus on cancer population	53
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients	53
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome	52
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways	52
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA	52
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis	52
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1–Wnt/β‐catenin–TFE3 feedback loop signalling	51
Mitochondrial and immune response dysregulation in melanoma recurrence	51
The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease	51
Synergistic inhibition of progesterone receptor‐A/B signalling by simvastatin and mifepristone in human uterine leiomyomas	50
Clinical medicine journals lag behind science journals with regards to “microbiota sequence” data availability	49