OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical and Translational Medicine is 50. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design	413
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC	365
	151
HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC	151
	128
Sendotypes predict worsening renal function in chronic kidney disease patients	123
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway	120
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma	101
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease	100
Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma	97
MicroRNAs affecting the susceptibility of melanoma cells to CD8⁺ T cell‐mediated cytolysis	96
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor	92
A droplet that releases stress: Drop‐printing for conformal bioelectronics at neural and soft‐tissue interfaces	91
Macrophage Cluster of Differentiation 163 promotes post‐infarction cardiac repair and preserves left ventricular function via osteopontin	84
Predictive medicine in a testis trio‐family through a combined multi‐omics approach	83
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases	82
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing	79
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases	77
Clinical translation potential of self‐inspired live‐cell super‐resolution microscopy	75
Regulatory mechanism of O‐linked N‐acetylglucosamine protein modification on autophagy in cancer	73
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells	70
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients	69
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma	68
Targeting lysine methyltransferase 2C deficiency: New frontiers in breast cancer therapy and prognosis	68
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma	66

The biological burden of conflict across populations worldwide	66
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways	65
Ubc9‐mediated SUMOylation of Ninj1 alleviates inflammatory responses in hepatic ischaemia/reperfusion injury	62
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation	62
Faecal zonulin, calprotectin and the infant microbiome in early life	62
Seize the engine: Emerging cell cycle targets in breast cancer	62
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma	61
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia	60
Quantum biology: From mechanisms to medicine	60
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma	59
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis	57
Recipient‐derived macrophages mediate acute cardiac allograft rejection via GSDMD‐induced pyroptosis mechanism	57
The emerging dialogue between synthetic genomics and clinical research	57
Deciphering the secret codes in N⁷‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases	56
Multi‐omics analysis revealed biomarkers for coronary atherosclerosis: Occurrence and development	55
The deubiquitinase OTUD3 plays a neuroprotective role by reducing ferroptosis induced by cerebral ischaemia reperfusion via stabilizing PLK1 via deubiquitination	55
Illuminating the genomic frontier of invasive non‐typhoidal Salmonella infections	54
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca²⁺ signalling	53
Mitochondrial and immune response dysregulation in melanoma recurrence	52
	51
Synergistic inhibition of progesterone receptor‐A/B signalling by simvastatin and mifepristone in human uterine leiomyomas	51
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target	51
NDP‐β‐d‐manno‐heptoses are small molecule agonists sensed by the vertebrates to discriminate organisms of different kingdoms	51
Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer	51
Multi‐omics molecular phenotyping reveals the potential mechanisms of chemotherapy response and resistance in small cell lung cancer	50