OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical and Translational Medicine is 51. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
	789
	285
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways	188
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design	157
Predictive medicine in a testis trio‐family through a combined multi‐omics approach	144
Seize the engine: Emerging cell cycle targets in breast cancer	144
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases	141
Sendotypes predict worsening renal function in chronic kidney disease patients	132
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma	122
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor	113
Faecal zonulin, calprotectin and the infant microbiome in early life	108
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma	107
The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease	105
Glucosamine regulates macrophage function in heart failure	104
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients	95
Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation	94
Lipids and genes: Regulatory roles of lipids in RNA expression	93
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives	91
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway	81
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging	80
Effect of epigenetic treatment on SST₂ expression in neuroendocrine tumour patients	80
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma	79
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells	79
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca²⁺ signalling	72
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease	68

HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC	67
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma	66
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing	66
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia	64
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC	63
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation	61
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome	60
Deciphering the secret codes in N⁷‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases	60
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1–Wnt/β‐catenin–TFE3 feedback loop signalling	60
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma	60
MicroRNAs affecting the susceptibility of melanoma cells to CD8⁺ T cell‐mediated cytolysis	60
Clinical translation potential of self‐inspired live‐cell super‐resolution microscopy	58
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis	56
The deubiquitinase OTUD3 plays a neuroprotective role by reducing ferroptosis induced by cerebral ischaemia reperfusion via stabilizing PLK1 via deubiquitination	55
Mitochondrial and immune response dysregulation in melanoma recurrence	55
Multi‐omics analysis revealed biomarkers for coronary atherosclerosis: Occurrence and development	54
Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma	54
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target	53
Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancer	53
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma	52
Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer	52
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases	52
	51
PIM1 genetic alterations associated with distinct molecular profiles, phenotypes and drug responses in diffuse large B‐cell lymphoma	51
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA	51
Unlocking the potential of T‐cell metabolism reprogramming: Advancing single‐cell approaches for precision immunotherapy in tumour immunity	51
The novel role of circular RNA ST3GAL6 on blocking gastric cancer malignant behaviours through autophagy regulated by the FOXP2/MET/mTOR axis	51