OOIR: Observatory of International Research

Papers

(The H4-Index of Computational and Structural Biotechnology Journal is 48. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
EthnoHERBS: Harnessing traditional herbal knowledge for biodiversity conservation and innovative health solutions	269
WUREN: Whole-modal union representation for epitope prediction	243
Agreement and disagreement in pediatric functional neurological symptom disorders: Comparing patient reported outcome measures (PROMs) and clinician assessments	182
Comprehensive exploration of JQ1 and GSK2801 targets in breast cancer using network pharmacology and molecular modeling approaches	161
Corrigendum to “Cryo-EM reveals architectural diversity in active rotavirus particles” [Comput. Struct. Biotechnol. J. 17 (2019) 1178–1183]	152
In silico and in vitro approaches allow the identification of the Prosystemin molecular network	151
Consistencies and contradictions in different polymer models of chromatin architecture	134
VTAM: A robust pipeline for validating metabarcoding data using controls	119
CKATool: A clinical kinematic analysis toolbox for upper limb rehabilitation	113
Design rules applied to silver nanoparticles synthesis: A practical example of machine learning application.	107
From sequence to function through structure: Deep learning for protein design	92
Evolution is in the details: Regulatory differences in modern human and Neanderthal	89
Phylogenetic tree-based amino acid sequence generation for proteomics data analysis of unknown species	88
Ranking pre-trained speech embeddings in Parkinson's disease detection: Does Wav2Vec 2.0 outperform its 1.0 version across speech modes and languages?	86
The influence of HIV sense and antisense transcripts on stochastic HIV transcription and reactivation	85
DiabetesOmic: A comprehensive multi-omics diabetes database	81
Structural elucidation of four fungal hydrophobins belonging to classes I and II: Results from Alphafold and accelerated molecular dynamics simulations	80
Predicting cellular adaptation proteins dependent on eIF2α regulation under stress conditions: Physiological and pathophysiological implications in neuronal function	71
Altered heme metabolism and hemoglobin concentration due to empirical antibiotics-induced gut dysbiosis in preterm infants	67
A miRNA signature linked to high lipoprotein (a) and coronary calcification in familial hypercholesterolaemia	67
MMRT: MultiMut Recursive Tree for predicting functional effects of high-order protein variants from low-order variants	66
Corrigendum to “Maternal Clostridium butyricum supplementation during late gestation and lactation enhances gut bacterial communities, milk quality, and reduces piglet diarrhea” [Comput Struct Biotech	66
The second intracellular loop of the yeast Trk1 potassium transporter is involved in regulation of activity, and interaction with 14–3-3 proteins	62
Towards predicting implant-induced fibrosis: A standardized network model of macrophage-fibroblast interactions	62
Deep5mC: Predicting 5-methylcytosine (5mC) methylation status using a deep learning transformer approach	62

Predictive dynamic control accurately maps the design space for 2,3-butanediol production	61
Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA	61
Statistical methods for Mendelian randomization in genome-wide association studies: A review	61
Integrated metabolomics and network analysis reveal changes in lipid metabolisms of tripterygium glycosides tablets in rats with collagen-induced arthritis	60
DIPAN: Detecting personalized intronic polyadenylation derived neoantigens from RNA sequencing data	58
Cell segmentation and representation with shape priors	57
Biomarker discovery process at binomial decision point (2BDP): Analytical pipeline to construct biomarker panel	57
cPEPmatch Webserver: A comprehensive tool and database to aid rational design of cyclic peptides for drug discovery	57
Entropy-extreme model for predicting the development of cyber epidemics at early stages	56
A drug repurposing method based on inhibition effect on gene regulatory network	56
MUG: A mutation overview of GPCR subfamily A17 receptors	55
Computation-aided studies related to the induction of specialized metabolite biosynthesis in microbial co-cultures: An introductory overview	53
What remains from living cells in bacterial lysate-based cell-free systems	52
Free energy landscape of the PI3Kα C-terminal activation	52
Discovery of a novel marine Bacteroidetes with a rich repertoire of carbohydrate-active enzymes	52
Predicting zeta potential of liposomes from their structure: A nano-QSPR model for DOPE, DC-Chol, DOTAP, and EPC formulations	52
Prediction of protein-ligand binding affinity with deep learning	51
The balance between photosynthesis and respiration explains the niche differentiation between Crocosphaera and Cyanothece	51
A novel exosome-derived prognostic signature and risk stratification for breast cancer based on multi-omics and systematic biological heterogeneity	50
Towards accurate and efficient diagnoses in nephropathology: An AI-based approach for assessing kidney transplant rejection	49
Identification and biophysical characterization of epitope atlas of Porcine Reproductive and Respiratory Syndrome Virus	49
Automated machine learning in nanotoxicity assessment: A comparative study of predictive model performance	49
Advanced biokinetic and hydrodynamic modelling to support and optimize the design of full-scale high rate algal ponds	48