OOIR: Observatory of International Research

Papers

(The H4-Index of Computational and Structural Biotechnology Journal is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Predicting cellular adaptation proteins dependent on eIF2α regulation under stress conditions: Physiological and pathophysiological implications in neuronal function	243
Corrigendum to “Maternal Clostridium butyricum supplementation during late gestation and lactation enhances gut bacterial communities, milk quality, and	211
Phylogenetic tree-based amino acid sequence generation for proteomics data analysis of unknown species	203
macpie: Scalable workflow for high-throughput transcriptomic profiling	169
MMRT: MultiMut Recursive Tree for predicting functional effects of high-order protein variants from low-order variants	161
A miRNA signature linked to high lipoprotein (a) and coronary calcification in familial hypercholesterolaemia	157
Pseudotimecascade Visualizes Gene Expression Cascade in Pseudotime Analysis	139
The influence of HIV sense and antisense transcripts on stochastic HIV transcription and reactivation	121
Identification of a Novel Trifluoromethyl-Bearing Flavonoid as a Promising Androgen Receptor Antagonist: Structure-Based Virtual Screening and In Vitro Study	110
SnakeAltPromoter Facilitates Differential Alternative Promoter Analysis	98
Ecological and Functional Stratification of the Stool Microbiome Predicts Response to Immune Checkpoint Inhibitors across Cancer Types	86
Consistencies and contradictions in different polymer models of chromatin architecture	84
In silico and in vitro approaches allow the identification of the Prosystemin molecular network	81
Identification and biophysical characterization of epitope atlas of Porcine Reproductive and Respiratory Syndrome Virus	79
MUG: A mutation overview of GPCR subfamily A17 receptors	79
cPEPmatch Webserver: A comprehensive tool and database to aid rational design of cyclic peptides for drug discovery	77
Predictive dynamic control accurately maps the design space for 2,3-butanediol production	77
Free energy landscape of the PI3Kα C-terminal activation	75
Corrigendum to “Cryo-EM reveals architectural diversity in active rotavirus particles” [Comput. Struct. Biotechnol. J. 17 (2019) 1178–1183]	72
CRUSADE project: Recycling technologies for ELV components to create a sustainable source of market grade materials for EU applications	71
From latent dynamics to data geometry: Nonlinear diffusion modelling for protein structures	69
CKATool: A clinical kinematic analysis toolbox for upper limb rehabilitation	68
Biomarker discovery process at binomial decision point (2BDP): Analytical pipeline to construct biomarker panel	65
Computation-aided studies related to the induction of specialized metabolite biosynthesis in microbial co-cultures: An introductory overview	65
Agreement and disagreement in pediatric functional neurological symptom disorders: Comparing patient reported outcome measures (PROMs) and clinician assessments	64

The second intracellular loop of the yeast Trk1 potassium transporter is involved in regulation of activity, and interaction with 14–3-3 proteins	63
Comprehensive exploration of JQ1 and GSK2801 targets in breast cancer using network pharmacology and molecular modeling approaches	62
Computational fluid dynamics modeling and simulation of nanoparticle-tumor interaction: Systematic literature review	61
Integrative Multiomics and Single-Cell Profiling Identify TNFRSF1A ⁺ Macrophages as a Prognostic and Therapeutic Target in Diffuse Large B-cell Lymph	59
Evolution is in the details: Regulatory differences in modern human and Neanderthal	59
Towards predicting implant-induced fibrosis: A standardized network model of macrophage-fibroblast interactions	58
Cell segmentation and representation with shape priors	56
Optimized Quantitative Bacterial Two-Hybrid (qB2H) for Protein–Protein Interaction Assessment	55
A novel exosome-derived prognostic signature and risk stratification for breast cancer based on multi-omics and systematic biological heterogeneity	54
VTAM: A robust pipeline for validating metabarcoding data using controls	54
Radiomic clustering using graph network techniques coupled with unbalanced optimal transport	52
DiabetesOmic: A comprehensive multi-omics diabetes database	50
Altered heme metabolism and hemoglobin concentration due to empirical antibiotics-induced gut dysbiosis in preterm infants	50
DIPAN: Detecting personalized intronic polyadenylation derived neoantigens from RNA sequencing data	50
Prediction of protein-ligand binding affinity with deep learning	48
Gut microbiome enterotypes and temporal variations during a six-month inulin-supplemented weight loss randomized controlled trial in Thai children with obesity	46
Integrated metabolomics and network analysis reveal changes in lipid metabolisms of tripterygium glycosides tablets in rats with collagen-induced arthritis	46
A drug repurposing method based on inhibition effect on gene regulatory network	45
Optimizing Histatin 5: Effects of K13 and K17 Substitutions on Proteolytic Stability and Antifungal Activity	45
Ranking pre-trained speech embeddings in Parkinson's disease detection: Does Wav2Vec 2.0 outperform its 1.0 version across speech modes and languages?	45
Data pre-processing for analyzing microbiome data – A mini review	45
What remains from living cells in bacterial lysate-based cell-free systems	45