OOIR: Observatory of International Research

Papers

(The H4-Index of Computational and Structural Biotechnology Journal is 46. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Evidence of a SARS-CoV-2 double Spike mutation D614G/S939F potentially affecting immune response of infected subjects	253
Multi-omics landscape and clinical significance of a SMAD4-driven immune signature: Implications for risk stratification and frontline therapies in pancreatic cancer	235
EthnoHERBS: Harnessing traditional herbal knowledge for biodiversity conservation and innovative health solutions	178
WUREN: Whole-modal union representation for epitope prediction	153
NGS allele counts versus called genotypes for testing genetic association	143
The second intracellular loop of the yeast Trk1 potassium transporter is involved in regulation of activity, and interaction with 14–3-3 proteins	140
Agreement and disagreement in pediatric functional neurological symptom disorders: Comparing patient reported outcome measures (PROMs) and clinician assessments	127
Comprehensive exploration of JQ1 and GSK2801 targets in breast cancer using network pharmacology and molecular modeling approaches	112
Corrigendum to “Cryo-EM reveals architectural diversity in active rotavirus particles” [Comput. Struct. Biotechnol. J. 17 (2019) 1178–1183]	111
In silico and in vitro approaches allow the identification of the Prosystemin molecular network	103
An integrated protein structure fitness scoring approach for identifying native-like model structures	89
Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA	87
From sequence to function through structure: Deep learning for protein design	82
UPIMAPI, reCOGnizer and KEGGCharter: Bioinformatics tools for functional annotation and visualization of (meta)-omics datasets	81
Optimizing the Illumina COVIDSeq laboratorial and bioinformatics pipeline on thousands of samples for SARS-CoV-2 Variants of Concern tracking	81
Predictive dynamic control accurately maps the design space for 2,3-butanediol production	77
CKATool: A clinical kinematic analysis toolbox for upper limb rehabilitation	70
Predicting zeta potential of liposomes from their structure: A nano-QSPR model for DOPE, DC-Chol, DOTAP, and EPC formulations	67
Identification and biophysical characterization of epitope atlas of Porcine Reproductive and Respiratory Syndrome Virus	67
Free energy landscape of the PI3Kα C-terminal activation	62
Using molecular dynamics simulations to interrogate T cell receptor non-equilibrium kinetics	62
Integrated metabolomics and network analysis reveal changes in lipid metabolisms of tripterygium glycosides tablets in rats with collagen-induced arthritis	61
DIPAN: Detecting personalized intronic polyadenylation derived neoantigens from RNA sequencing data	60
Improved inter-residue contact prediction via a hybrid generative model and dynamic loss function	60
Biomarker discovery process at binomial decision point (2BDP): Analytical pipeline to construct biomarker panel	60

Towards accurate and efficient diagnoses in nephropathology: An AI-based approach for assessing kidney transplant rejection	60
dsCellNet: A new computational tool to infer cell–cell communication networks in the developing and aging brain	60
cPEPmatch Webserver: A comprehensive tool and database to aid rational design of cyclic peptides for drug discovery	59
Automated machine learning in nanotoxicity assessment: A comparative study of predictive model performance	56
Artificial intelligence predictive system of individual survival rate for lung adenocarcinoma	55
Cell segmentation and representation with shape priors	55
VTAM: A robust pipeline for validating metabarcoding data using controls	54
A miRNA signature linked to high lipoprotein (a) and coronary calcification in familial hypercholesterolaemia	52
Corrigendum to “Maternal Clostridium butyricum supplementation during late gestation and lactation enhances gut bacterial communities, milk quality, and reduces piglet diarrhea” [Comput Struct Biotech	52
Towards predicting implant-induced fibrosis: A standardized network model of macrophage-fibroblast interactions	52
Predicting cellular adaptation proteins dependent on eIF2α regulation under stress conditions: Physiological and pathophysiological implications in neuronal function	50
The influence of HIV sense and antisense transcripts on stochastic HIV transcription and reactivation	50
Altered heme metabolism and hemoglobin concentration due to empirical antibiotics-induced gut dysbiosis in preterm infants	49
Deep5mC: Predicting 5-methylcytosine (5mC) methylation status using a deep learning transformer approach	49
Structural elucidation of four fungal hydrophobins belonging to classes I and II: Results from Alphafold and accelerated molecular dynamics simulations	49
Evolution is in the details: Regulatory differences in modern human and Neanderthal	48
Data pre-processing for analyzing microbiome data – A mini review	48
DiabetesOmic: A comprehensive multi-omics diabetes database	48
MMRT: MultiMut Recursive Tree for predicting functional effects of high-order protein variants from low-order variants	48
Phylogenetic tree-based amino acid sequence generation for proteomics data analysis of unknown species	47
Prediction of protein-ligand binding affinity with deep learning	47
Nextcast: A software suite to analyse and model toxicogenomics data	46
Advanced biokinetic and hydrodynamic modelling to support and optimize the design of full-scale high rate algal ponds	46
A novel exosome-derived prognostic signature and risk stratification for breast cancer based on multi-omics and systematic biological heterogeneity	46