OOIR: Observatory of International Research

Papers

(The H4-Index of Computational and Structural Biotechnology Journal is 38. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA	187
Optimizing the Illumina COVIDSeq laboratorial and bioinformatics pipeline on thousands of samples for SARS-CoV-2 Variants of Concern tracking	179
An integrated protein structure fitness scoring approach for identifying native-like model structures	149
Agreement and disagreement in pediatric functional neurological symptom disorders: Comparing patient reported outcome measures (PROMs) and clinician assessments	119
Identification of (Z)-2-benzylidene-dihydroimidazothiazolone derivatives as tyrosinase inhibitors: Anti-melanogenic effects and in silico studies	119
NGS allele counts versus called genotypes for testing genetic association	114
Network-based prioritization of cancer biomarkers by phenotype-driven module detection and ranking	102
Biomarker discovery process at binomial decision point (2BDP): Analytical pipeline to construct biomarker panel	92
The second intracellular loop of the yeast Trk1 potassium transporter is involved in regulation of activity, and interaction with 14–3-3 proteins	88
Comprehensive exploration of JQ1 and GSK2801 targets in breast cancer using network pharmacology and molecular modeling approaches	83
MUG: A mutation overview of GPCR subfamily A17 receptors	76
Integrated metabolomics and network analysis reveal changes in lipid metabolisms of tripterygium glycosides tablets in rats with collagen-induced arthritis	70
cPEPmatch Webserver: A comprehensive tool and database to aid rational design of cyclic peptides for drug discovery	68
Identification and biophysical characterization of epitope atlas of Porcine Reproductive and Respiratory Syndrome Virus	64
WUREN: Whole-modal union representation for epitope prediction	63
Design rules applied to silver nanoparticles synthesis: A practical example of machine learning application.	56
Corrigendum to “Cryo-EM reveals architectural diversity in active rotavirus particles” [Comput. Struct. Biotechnol. J. 17 (2019) 1178–1183]	55
Free energy landscape of the PI3Kα C-terminal activation	54
Evidence of a SARS-CoV-2 double Spike mutation D614G/S939F potentially affecting immune response of infected subjects	54
VTAM: A robust pipeline for validating metabarcoding data using controls	53
Entropy-extreme model for predicting the development of cyber epidemics at early stages	53
Artificial intelligence predictive system of individual survival rate for lung adenocarcinoma	50
The balance between photosynthesis and respiration explains the niche differentiation between Crocosphaera and Cyanothece	50
Nextcast: A software suite to analyse and model toxicogenomics data	49
DIPAN: Detecting personalized intronic polyadenylation derived neoantigens from RNA sequencing data	49

EthnoHERBS: Harnessing traditional herbal knowledge for biodiversity conservation and innovative health solutions	48
In silico and in vitro approaches allow the identification of the Prosystemin molecular network	48
Predicting zeta potential of liposomes from their structure: A nano-QSPR model for DOPE, DC-Chol, DOTAP, and EPC formulations	48
Multi-omics landscape and clinical significance of a SMAD4-driven immune signature: Implications for risk stratification and frontline therapies in pancreatic cancer	47
Discovery of a novel marine Bacteroidetes with a rich repertoire of carbohydrate-active enzymes	46
Advanced biokinetic and hydrodynamic modelling to support and optimize the design of full-scale high rate algal ponds	43
Improved inter-residue contact prediction via a hybrid generative model and dynamic loss function	42
dsCellNet: A new computational tool to infer cell–cell communication networks in the developing and aging brain	41
Using molecular dynamics simulations to interrogate T cell receptor non-equilibrium kinetics	40
A novel exosome-derived prognostic signature and risk stratification for breast cancer based on multi-omics and systematic biological heterogeneity	40
Predictive dynamic control accurately maps the design space for 2,3-butanediol production	39
A drug repurposing method based on inhibition effect on gene regulatory network	39
Data pre-processing for analyzing microbiome data – A mini review	39
Deep5mC: Predicting 5-methylcytosine (5mC) methylation status using a deep learning transformer approach	38
Automated machine learning in nanotoxicity assessment: A comparative study of predictive model performance	38
MMRT: MultiMut Recursive Tree for predicting functional effects of high-order protein variants from low-order variants	38