OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Oral Microbiology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Early pregnancy is characterized by a significant decrease in the diversity of the oral microbiome and strong associations with lifestyle and conception method	298
Bidirectional effects of neutrophils on Streptococcus oralis biofilms in vitro	138
Porphyromonas gingivalis -OMVs promote the epithelial-mesenchymal transition of oral squamous cell carcinoma by inhibiting ferroptosis through the NF-κB pathway	119
Novel biomarker identification for oral squamous cell carcinoma development in nonsmoker, nondrinker, and nonchewer patients using third-generation sequencing of oral microbiome	99
The effect of different sweeteners on the oral microbiome: a randomized clinical exploratory pilot study	66
Role of immunostimulatory deoxycytidylate-phosphate-deoxyguanylate (CpG) motifs in oral bacteria associated with oral diseases	56
Fusobacterium nucleatum as an oral bacteria promotes the carcinogenesis of laryngeal cancer via upregulating YWHAZ	56
Altered oral microbiome composition in mental disorders: a systematic review and meta-analysis	55
Altered oral microbiomes in patients with prolonged disorders of consciousness	51
Novel approaches on root canal disinfection methods against E. faecalis	46
Interplay between genetically predicted gut microbiota and chronic apical periodontitis: a Mendelian randomization analysis	41
Inhibitory effect of helium cold atmospheric plasma on cariogenic biofilms	33
Oral microbiome diversity and all-cause mortality in hypertensive adults: findings from a nationally representative cohort	33
Prevotella intermedia oral infection induces cognitive impairment in C57BL/6 mice via neuroinflammation and barrier damage	32
Guideline for the analysis of the microbial communities of the human upper airways	32
Cytokine release and NLRP3 inflammasome activation induced by low-abundance oral bacterial biofilms	29
Interaction between microorganisms and dental material surfaces: general concepts and research progress	29
Detection of Epstein-Barr virus infection in primary junctional epithelial cell cultures	28
Nitrate reduction by salivary bacteria, glucose metabolism, and lifestyle	26
Impact of HbA1c control and type 2 diabetes mellitus exposure on the oral microbiome profile in the elderly population	26
The association between the oral microbiome and hypertension: a systematic review	25
Macrophage activation and invasion by P. gingivalis is modulated by PPAD and accessory fimbriae subunits	24
Organotypic model of the gingiva for studying bacterial and viral pathogens implicated in periodontitis	24
N -acyl homoserine lactones lactonase est816 suppresses biofilm formation and periodontitis in rats mediated by Aggregatibacter actinomycetemcomitans	23
Oral administration of Porphyromonas gingivalis to mice with diet-induced obesity impairs cognitive function associated with microglial activation in the brain	23

The importance of biofilm contamination control for dental unit waterlines: a multicenter assessment of the microbiota diversity of biofilm in dental unit waterlines	22
Efficacy of gigantol, a bibenzyl compound, against Porphyromonas gingivalis	21
Salivary and tonsillar microbiota across multiple sites in paediatric tonsillar hypertrophy and their associations with clinical factors	21
Distinct oral DNA viral signatures in rheumatoid arthritis: a Pilot study	20
Deficiency of dltD contributes to increased autolysis in Streptococcus mutans	19
Subgingival microbiome and adjunctive use of probiotics in the treatment of periodontitis in patients with diabetes: a secondary analysis of a randomized clinical trial	19
Characteristics of Candida albicans metabolism of glucose and two sugar substitutes, xylose and xylitol and effect of these substitutes on glucose metabo	19
The Porphyromonas gingivalis lipid A 1-phosphatase LpxE requires a functional type IX secretion system for its activity	18
Inflammatory response of gut, spleen, and liver in mice induced by orally administeredPorphyromonas gingivalis	18
Unveiling the complexity of early childhood caries: Candida albicans and Streptococcus mutans cooperative strategies in carbohydrate metab	18
Role of Enterococcus faecalis in refractory apical periodontitis: from pathogenicity to host cell response	17
Isolation of Streptococcus mutans in the gastrointestinal tract of corpses	17
Diagnostic oral microbiota signatures for gastric cancer and associations with carcinogenic signaling pathways	17
Characterization of the unique oral microbiome of children harboring Helicobacter pylori in the oral cavity	17
DNA virus tropism in healthy dental pulp: an in-situ reservoir site for torque teno virus and parvovirus B19	17
Ultrasmall epibiont Nanosynbacter lyticus strain TM7x and host bacteria transcriptional activity after initial host parasitism	16
Amoxicillin-metronidazole disk for antimicrobial susceptibility testing of subgingival bacteria	16
Patients with periodontitis exhibit persistent dysbiosis of the gut microbiota and distinct serum metabolome	16
Longitudinal profiles of oral microbiome in patients with nasopharyngeal carcinoma and their prognostic implications	16
Newly identified pathogens in periodontitis: evidence from an association and an elimination study	15
Inhibition of BTK and SYK attenuates Porphyromonas gingivalis -induced activation of the pyroptosis pathway and inflammation in host cells	15
Effective disinfecting of negative pressure pipelines of DCUs reduces the risk of cross infection in dental care	15
Dihydromyricetin attenuates biofilm formation and virulence in Streptococcus mutans, the key pathogen underlying dental caries	15
Oral microbiota composition in children and adults during Spanish COVID-19 lockdown: impact of home self-confinement and SARS-CoV-2 infection	15
Is systemic inflammation a missing link between oral microbiome and oral squamous cell carcinoma? Results from multi-omics integration analyses	15
Oxidative stress response: a critical factor affecting the ecological competitiveness of Streptococcus mutans	14
Supragingival Actinomyces naeslundii aggravates metabolic dysfunction-associated fatty liver disease via the oral–gut axis	14
Dysbiosis of the oropharyngeal microbiota in COVID-19: distinct profiles in patients with severe respiratory symptoms	14
Feasibility of oral microbiome profiles associated with oral squamous cell carcinoma	14
Effect of implant abutment surface treatments on bacterial biofilm composition and structure	14
Transition of oral microbiome profile in HIV-infected Indonesian patients: the role of antiretroviral therapy	14
The dynamic elimination effect of local adjuvant therapy on the periodontal microbiota	13
Healthy lifestyle and periodontitis: a multi-omics cross-sectional study in a Chinese cohort	13
Methanobrevibacter oralis : a comprehensive review	13
Correlation between oral microbiota and dry socket at different time periods on tooth extraction	13
Dual transcriptome of Streptococcus mutans and Candida albicans interplay in biofilms	13
Arginine-specific gingipains (RgpA/RgpB) knockdown modulates neutrophil machinery	13
The oral microbiome as a regulatory hub for systemic health: a systematic review of mechanistic links and clinical implications	12
The effects of nitrate on the oral microbiome: a systematic review investigating prebiotic potential	12
Effect of Helicobacter pylori on enamel and dentin development – an in vitro study in mice	12
Antagonistic interaction between two key endodontic pathogens Enterococcus faecalis and Fusobacterium nucleatum	12
Porphyromonas gingivalis-Helicobacter pylori co-incubation enhances Porphyromonas gingivalis virulence and increases migration of infected human oral keratinocytes	11
Enhanced dominance of nitrate-reducing bacteria using a combination of nitrate and erythritol in in vitro cultured oral biofilm	11
Influence of dental implant surfaces on oral biofilms and host immune response	10
Dental caries shallow-layer microbe harvest and data display method shows taxa pre-harvest spatial positions, absolute and relative abundance and diversity related to lesion pulpal depth	10
High prevalence of antibiotic resistance of Streptococcus species in saliva from non-hospitalized adults – a pilot study	10
Association between oral microbial shifts and polycystic ovary syndrome: a systematic review	10
Evaluation of a Burkholderia ambifaria strain from plants as a novel promising probiotic in dental caries management	10
Profiles of oral microbiome associated with nasogastric tube feeding	10
Functional characteristics of membrane vesicles produced by Streptococcus mitis	10

RE: colonization of bacterial and viral respiratory pathogens among healthcare workers in China during COVID-19 pandemic	10
Microbiome variability and role of Candida albicans in site-specific dental plaques in orthodontic adolescent patients with white spot lesions	9
Correction	9
Comparison of the performance of MiSeq and NovaSeq in oral microbiome study	9
Characterization of MreCD in Streptococcus mutans	9
Genetic characterization of glyoxalase pathway in oral streptococci and its contribution to interbacterial competition	9
Functional profiling of the oral microbiome reveals microbial and oncogenic signatures in never-smoking female patients with oral squamous cell carcinoma	9
Streptococcus dentisani 7746 encodes a cocktail of 14 bacteriocins associated with Com and Blp-like quorum sensing regu	9