OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Oral Microbiology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Role of immunostimulatory deoxycytidylate-phosphate-deoxyguanylate (CpG) motifs in oral bacteria associated with oral diseases	336
Bidirectional effects of neutrophils on Streptococcus oralis biofilms in vitro	130
Novel biomarker identification for oral squamous cell carcinoma development in nonsmoker, nondrinker, and nonchewer patients using third-generation sequencing of oral microbiome	113
Early pregnancy is characterized by a significant decrease in the diversity of the oral microbiome and strong associations with lifestyle and conception method	65
The effect of different sweeteners on the oral microbiome: a randomized clinical exploratory pilot study	65
Fusobacterium nucleatum as an oral bacteria promotes the carcinogenesis of laryngeal cancer via upregulating YWHAZ	61
Oral microbiome diversity and composition in inflammatory bowel disease patients with periodontitis	59
Porphyromonas gingivalis -OMVs promote the epithelial-mesenchymal transition of oral squamous cell carcinoma by inhibiting ferroptosis through the NF-κB pathway	54
Prevotella intermedia oral infection induces cognitive impairment in C57BL/6 mice via neuroinflammation and barrier damage	45
Interplay between genetically predicted gut microbiota and chronic apical periodontitis: a Mendelian randomization analysis	39
Oral microbiome diversity and all-cause mortality in hypertensive adults: findings from a nationally representative cohort	36
Antibacterial and anti-biofilm effects of postbiotic mediator derived from Jeotgal isolate Lactiplantibacillus plantarum	34
Altered oral microbiome composition in mental disorders: a systematic review and meta-analysis	34
Inhibitory effect of helium cold atmospheric plasma on cariogenic biofilms	32
Altered oral microbiomes in patients with prolonged disorders of consciousness	31
Interaction between microorganisms and dental material surfaces: general concepts and research progress	31
Novel approaches on root canal disinfection methods against E. faecalis	30
Oral administration of Porphyromonas gingivalis to mice with diet-induced obesity impairs cognitive function associated with microglial activation in the brain	29
The importance of biofilm contamination control for dental unit waterlines: a multicenter assessment of the microbiota diversity of biofilm in dental unit waterlines	29
Organotypic model of the gingiva for studying bacterial and viral pathogens implicated in periodontitis	27
Macrophage activation and invasion by P. gingivalis is modulated by PPAD and accessory fimbriae subunits	26
Cytokine release and NLRP3 inflammasome activation induced by low-abundance oral bacterial biofilms	25
The association between the oral microbiome and hypertension: a systematic review	24
Nitrate reduction by salivary bacteria, glucose metabolism, and lifestyle	24
Detection of Epstein-Barr virus infection in primary junctional epithelial cell cultures	24

N -acyl homoserine lactones lactonase est816 suppresses biofilm formation and periodontitis in rats mediated by Aggregatibacter actinomycetemcomitans	23
Impact of HbA1c control and type 2 diabetes mellitus exposure on the oral microbiome profile in the elderly population	23
Deficiency of dltD contributes to increased autolysis in Streptococcus mutans	22
Salivary and tonsillar microbiota across multiple sites in paediatric tonsillar hypertrophy and their associations with clinical factors	22
Characteristics of Candida albicans metabolism of glucose and two sugar substitutes, xylose and xylitol and effect of these substitutes on glucose metabo	21
Subgingival microbiome and adjunctive use of probiotics in the treatment of periodontitis in patients with diabetes: a secondary analysis of a randomized clinical trial	20
CRISPR spacer profiling and prophage mining reveal diverse bacteriophages associated with Streptococcus Mutans	20
Efficacy of gigantol, a bibenzyl compound, against Porphyromonas gingivalis	20
The Porphyromonas gingivalis lipid A 1-phosphatase LpxE requires a functional type IX secretion system for its activity	20
Distinct oral DNA viral signatures in rheumatoid arthritis: a Pilot study	19
Isolation of Streptococcus mutans in the gastrointestinal tract of corpses	19
A prospective cohort study exploring salivary microbial predictors of white spot lesions during fixed orthodontic treatment	19
DNA virus tropism in healthy dental pulp: an in-situ reservoir site for torque teno virus and parvovirus B19	18
Amoxicillin-metronidazole disk for antimicrobial susceptibility testing of subgingival bacteria	18
Diagnostic oral microbiota signatures for gastric cancer and associations with carcinogenic signaling pathways	18
Ultrasmall epibiont Nanosynbacter lyticus strain TM7x and host bacteria transcriptional activity after initial host parasitism	18
Oral microbiota composition in children and adults during Spanish COVID-19 lockdown: impact of home self-confinement and SARS-CoV-2 infection	17
Newly identified pathogens in periodontitis: evidence from an association and an elimination study	17
Characterization of the unique oral microbiome of children harboring Helicobacter pylori in the oral cavity	17
Role of Enterococcus faecalis in refractory apical periodontitis: from pathogenicity to host cell response	17
Longitudinal profiles of oral microbiome in patients with nasopharyngeal carcinoma and their prognostic implications	17
Unveiling the complexity of early childhood caries: Candida albicans and Streptococcus mutans cooperative strategies in carbohydrate metab	17
Transition of oral microbiome profile in HIV-infected Indonesian patients: the role of antiretroviral therapy	16
Dihydromyricetin attenuates biofilm formation and virulence in Streptococcus mutans, the key pathogen underlying dental caries	16
Is systemic inflammation a missing link between oral microbiome and oral squamous cell carcinoma? Results from multi-omics integration analyses	16
Patients with periodontitis exhibit persistent dysbiosis of the gut microbiota and distinct serum metabolome	16
Cell-type-specific actions of carnosic acid against Porphyromonas gingivalis -induced proliferation in liver cancer cells	15
Inhibition of BTK and SYK attenuates Porphyromonas gingivalis -induced activation of the pyroptosis pathway and inflammation in host cells	15
Oxidative stress response: a critical factor affecting the ecological competitiveness of Streptococcus mutans	15
Effective disinfecting of negative pressure pipelines of DCUs reduces the risk of cross infection in dental care	15
Supragingival Actinomyces naeslundii aggravates metabolic dysfunction-associated fatty liver disease via the oral–gut axis	14
Correlation between oral microbiota and dry socket at different time periods on tooth extraction	13
Arginine-specific gingipains (RgpA/RgpB) knockdown modulates neutrophil machinery	13
The dynamic elimination effect of local adjuvant therapy on the periodontal microbiota	13
Dysbiosis of the oropharyngeal microbiota in COVID-19: distinct profiles in patients with severe respiratory symptoms	13
Antagonistic interaction between two key endodontic pathogens Enterococcus faecalis and Fusobacterium nucleatum	13
Feasibility of oral microbiome profiles associated with oral squamous cell carcinoma	13
Methanobrevibacter oralis : a comprehensive review	12
Dual transcriptome of Streptococcus mutans and Candida albicans interplay in biofilms	12
The association between tongue features and tongue coating microbiota and gastrointestinal cancer: a systematic review and meta-analysis	12
Suprathreshold non-volatile flavour perception is associated with multiple species rather than any single species via bacterial metabolism	12
Effect of implant abutment surface treatments on bacterial biofilm composition and structure	11
Effect of Helicobacter pylori on enamel and dentin development – an in vitro study in mice	11
Healthy lifestyle and periodontitis: a multi-omics cross-sectional study in a Chinese cohort	11
The effects of nitrate on the oral microbiome: a systematic review investigating prebiotic potential	11
Profiles of oral microbiome associated with nasogastric tube feeding	11
Combined treatment with bacteriophages and sodium hypochlorite against E. faecalis biofilm in an in vitro	10
Association between oral microbial shifts and polycystic ovary syndrome: a systematic review	10
Functional characteristics of membrane vesicles produced by Streptococcus mitis	10
Influence of dental implant surfaces on oral biofilms and host immune response	10

High prevalence of antibiotic resistance of Streptococcus species in saliva from non-hospitalized adults – a pilot study	10
Association between the oral microbiome and clinical indicators of resectable non-small cell lung cancer (NSCLC)	10
Evaluation of a Burkholderia ambifaria strain from plants as a novel promising probiotic in dental caries management	10
Dental caries shallow-layer microbe harvest and data display method shows taxa pre-harvest spatial positions, absolute and relative abundance and diversity related to lesion pulpal depth	10
The oral microbiome as a regulatory hub for systemic health: a systematic review of mechanistic links and clinical implications	9
Enhanced dominance of nitrate-reducing bacteria using a combination of nitrate and erythritol in in vitro cultured oral biofilm	9
Porphyromonas gingivalis-Helicobacter pylori co-incubation enhances Porphyromonas gingivalis virulence and increases migration of infected human oral keratinocytes	9
Fibrinogen was associated with subgingival microbiome in periodontal diseases: a pilot study	9
Periodontal status and microbial profiles across the clinical spectrum of liver cirrhosis	9
Comparison of the performance of MiSeq and NovaSeq in oral microbiome study	9
RE: colonization of bacterial and viral respiratory pathogens among healthcare workers in China during COVID-19 pandemic	8
Streptococcus dentisani 7746 encodes a cocktail of 14 bacteriocins associated with Com and Blp-like quorum sensing regu	8
Functional profiling of the oral microbiome reveals microbial and oncogenic signatures in never-smoking female patients with oral squamous cell carcinoma	8
Oral health and infective endocarditis among high-risk individuals: a nationwide register-based study	8
Microbial mechanisms and therapeutic interventions in the periodontitis-inflammatory bowel disease axis: a comprehensive review	8
Genetic characterization of glyoxalase pathway in oral streptococci and its contribution to interbacterial competition	8
Correction	8
Understanding the bacterial compositional network associations between oral and gut microbiome within healthy Koreans	8
Altered composition of the oral microbiome in integrin beta 6-deficient mouse	8
Screening of heat-killed lactic acid bacteria based on inhibitory activity against oral bacteria and effects of oral administration of heat-killed Ligilactobacillus salivarius	8
Microbiome variability and role of Candida albicans in site-specific dental plaques in orthodontic adolescent patients with white spot lesions	8
Characterization of MreCD in Streptococcus mutans	8
Capsaicin inhibits cariogenic Streptococcus mutans–Candida albicans cross-kingdom biofilms	8
Vendor-specific microbiomes influence oral cancer development and its response to Streptococcus mitis intervention in mice	8
Microbial manipulators: Fusobacterium nucleatum modulates the tumor immune microenvironment in colorectal cancer	8