OOIR: Observatory of International Research

Papers

(The H4-Index of Pharmaceutics is 99. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Editorial for Special Issue: “Additive Manufacturing Approaches to Produce Drug Delivery Systems”	794
Effects of Dimerization, Dendrimerization, and Chirality in p-BthTX-I Peptide Analogs on the Antibacterial Activity and Enzymatic Inhibition of the SARS-CoV-2 PLpro Protein	518
Synthesis of Terminal-Alkylated PEGs with Imine Spacer to Form Iminium Mono-Ion Complexes for pDNA Delivery into Skeletal Muscle	384
A Formulation–Process–Product Integrated Design Method for Accelerating Pharmaceutical Tablet Development via the High-Shear Wet Granulation and Tableting Route	339
In Vitro Comparative Study on Oppositely Charged Donepezil-Loaded Intranasal Liposomes	338
Comparing the Altis RepliGut Organoid System to MDCK Monolayers in Predicting the Oral Absorption of Lenalidomide	326
Etrog Citron (Citrus medica) as a Novel Source of Antiviral Agents: Overview of Its Bioactive Phytochemicals and Delivery Approaches	315
Modulation of TRPV1 on Odontoblast-like Cells Using Capsazepine-Loaded Nanogels	313
Influenza Virus Inactivated by Heavy Ion Beam Irradiation Stimulates Antigen-Specific Immune Responses	300
Perceived Usability of Tablet Crushers: Comparison of Devices by People with and without Limited Hand Functions	299
Isolation and Characterization of an Anti-Osteoporotic Compound from Melia toosendan Fructus	294
A Human Feedback Strategy for Photoresponsive Molecules in Drug Delivery: Utilizing GPT-2 and Time-Dependent Density Functional Theory Calculations	245
Drug–Drug Interactions in Patients with Acute Respiratory Distress Syndrome	236
Validation of an LC-MS/MS Method for the Simultaneous Intracellular Quantification of the CDK4/6 Inhibitor Abemaciclib and the EZH2 Inhibitors GSK126 and Tazemetostat	231
Stability Studies of Clonazepam 2.5 mg/mL Oral Solution and 1 mg/mL Parenteral Solution in Pre-Filled Polypropylene Syringes	223
Natural Killer-Based Therapy: A Prospective Thought for Cancer Treatment Related to Diversified Drug Delivery Pathways	212
Oxaliplatin(IV) Prodrugs Functionalized with Gemcitabine and Capecitabine Induce Blockage of Colorectal Cancer Cell Growth—An Investigation of the Activation Mechanism and Their Nanoformulation	208
Physiologically Based Pharmacokinetic Modeling to Assess Antiretroviral–BTK Inhibitor Interactions and Provide Recommendations for Co-Administration Regimens	207
Anti-Inflammatory Effects of Chamaecyparis obtusa (Siebold & Zucc.) Endl. Leaf Extract Fermented by Ganoderma applanatum Mycelia	205
Exosomes as CNS Drug Delivery Tools and Their Applications	205
Drug Delivery Systems Based on Metal–Organic Frameworks for Tumor Immunotherapy	204
The Impact of Doxycycline as an Adjunctive Therapy on Prostate-Specific Antigen, Quality of Life, and Cognitive Function in Metastatic Prostate Cancer Patients: A Phase II Randomized Controlled Trial	199
Exploring Variability in Rifampicin Plasma Exposure and Development of Anti-Tuberculosis Drug-Induced Liver Injury among Patients with Pulmonary Tuberculosis from the Pharmacogenetic Perspective	194
CRISPR/Cas9-Mediated Customizing Strategies for Adoptive T-Cell Therapy	194
Pharmacological Functions, Synthesis, and Delivery Progress for Collagen as Biodrug and Biomaterial	193

Microfluidic and Turbulent Mixing for mRNA LNP Vaccines	189
Modified Curcuminoid-Rich Extract Liposomal CRE-SDInhibits Osteoclastogenesis via the Canonical NF-κB Signaling Pathway	168
Self-Assembling Injectable Hydrogel for Controlled Drug Delivery of Antimuscular Atrophy Drug Tilorone	168
Hyaluronic Acid-Based Nanomaterials Applied to Cancer: Where Are We Now?	166
Wound Healing Efficacy of Rosuvastatin Transethosomal Gel, I Optimal Optimization, Histological and In Vivo Evaluation	164
Controversial Interactions of Tacrolimus with Dietary Supplements, Herbs and Food	159
Retention Time Extended by Nanoparticles Improves the Eradication of Highly Antibiotic-Resistant Helicobacter pylori	159
Hydrogel-Based Therapeutic Strategies for Periodontal Tissue Regeneration: Advances, Challenges, and Future Perspectives	159
Chitosan Nanoparticles Loaded Poloxamer 407 Gel for Transungual Delivery of Terbinafine HCl	158
HIFU-CCL19/21 Axis Enhances Dendritic Cell Vaccine Efficacy in the Tumor Microenvironment	158
Cardioprotective and Hepatoprotective Potential of Silymarin in Paracetamol-Induced Oxidative Stress	157
A kNGR Peptide-Tethered Lipid–Polymer Hybrid Nanocarrier-Based Synergistic Approach for Effective Tumor Therapy: Development, Characterization, Ex-Vivo, and In-Vivo Assessment	157
Formulation of Dosage Forms with Proton Pump Inhibitors: State of the Art, Challenges and Future Perspectives	156
A Validated Chiral LC–MS/MS Method for the Enantioselective Determination of (S)-(+)- and (R)-(-)-Ibuprofen in Dog Plasma: Its Application to a Pharmacokinetic Study	155
Gene Therapy for Regenerative Medicine	153
Glioma-Associated Sialoglycans Drive the Immune Suppressive Phenotype and Function of Myeloid Cells	153
Hydroxyapatite Thin Films of Marine Origin as Sustainable Candidates for Dental Implants	150
Surfactant-Enabled Nanocarriers in Breast Cancer Therapy: Targeted Delivery and Multidrug Resistance Reversal	150
A Volumetric Absorptive Microsampling UPLC-MS/MS Method for Simultaneous Quantification of Tacrolimus, Mycophenolic Acid and Creatinine in Whole Blood of Renal Transplant Recipients	149
PSME4 Degrades Acetylated YAP1 in the Nucleus of Mesenchymal Stem Cells	147
Tunable Polymeric Mixed Micellar Nanoassemblies of Lutrol F127/Gelucire 44/14 for Oral Delivery of Praziquantel: A Promising Nanovector against Hymenolepis nana in Experimentally-Infected Rats	141
Delivery of RNAs to Specific Organs by Lipid Nanoparticles for Gene Therapy	141
Design of Liquid Formulation Based on F127-Loaded Natural Dimeric Flavonoids as a New Perspective Treatment for Leishmaniasis	138
Anomalous Water-Sorption Kinetics in ASDs	136
Transferability of Published Population Pharmacokinetic Models for Apixaban and Rivaroxaban to Subjects with Obesity Treated for Venous Thromboembolism: A Systematic Review and External Evaluations	136
Robust Inclusion Complex of Topotecan Comprised within a Rhodamine-Labeled β-Cyclodextrin: Competing Proton and Energy Transfer Processes	136
Locoregional Lymphatic Delivery Systems Using Nanoparticles and Hydrogels for Anticancer Immunotherapy	135
Polymeric Nanomicelles Loaded with Anandamide and Their Renal Effects as a Therapeutic Alternative for Hypertension Treatment by Passive Targeting	133
Fabrication and Evaluation of Isomalt-Based Microfibers as Drug Carrier Systems	133
Modified Linear Peptides Effectively Silence STAT-3 in Breast Cancer and Ovarian Cancer Cell Lines	131
Correction: van den Born-Bondt et al. Development of an Adaptable Qualification Test Set for Personnel Involved in Visual Inspection Procedures of Parenteral Drug Products Manufactured Under Good Manu	131
The First Report of In Vitro Antifungal and Antibiofilm Photodynamic Activity of Tetra-Cationic Porphyrins Containing Pt(II) Complexes against Candida albicans for Onychomycosis Treatment	130
Development of a Peptide-Based Nano-Sized Cathepsin B Inhibitor for Anticancer Therapy	130
Correction: Khalid et al. Development of Rapidly Dissolving Microneedles Integrated with Valsartan-Loaded Nanoliposomes for Transdermal Drug Delivery: In Vitro and Ex Vivo Evaluation. Pharmaceutics 20	130
Lung Inflammation Resolution by RvD1 and RvD2 in a Receptor-Dependent Manner	130
Delicate Hybrid Laponite–Cyclic Poly(ethylene glycol) Nanoparticles as a Potential Drug Delivery System	129
CAVPENET Peptide Inhibits Prostate Cancer Cells Proliferation and Migration through PP1γ-Dependent Inhibition of AKT Signaling	129
Dexamethasone-Loaded Ureasil Hydrophobic Membrane for Bone Guided Regeneration	126
Could Sodium-Glucose Co-Transporter-2 Inhibitors and Glucagon-like Peptide-1 Receptor Agonists Play a Role in Gout Treatment?	125
Synergistic Effects of Chemotherapy and Phototherapy on Ovarian Cancer Using Follicle-Stimulating Hormone Receptor-Mediated Liposomes Co-Loaded with SN38 and IR820	122
Characterization of Oil-in-Water Emulsions Prepared with Triblock Copolymer Poloxamer 407 and Low-Molecular-Mass Surfactant Mixtures as Carriers of Grape Pomace Waste Polyphenols	121
Natural Antimicrobials Block the Host NF-κB Pathway and Reduce Enterocytozoon hepatopenaei Infection Both In Vitro and In Vivo	121
Targeted Therapy of Acute Liver Injury via Cryptotanshinone-Loaded Biomimetic Nanoparticles Derived from Mesenchymal Stromal Cells Driven by Homing	118
Protection Against Toxoplasma gondii Lethal ME49 Challenge Induced by Influenza Virus-like Particles Containing Dense Granule Protein 14	118
Prostate Cancer-Targeting Liposome Loaded with Zinc Ion-Coordinated Photosensitizer for Enhanced Chemo-Photodynamic Therapy	117
Synthesis & Evaluation of Novel Mannosylated Neoglycolipids for Liposomal Delivery System Applications	115
Development of Liposome Systems for Enhancing the PK Properties of Bivalent PROTACs	114
Pharmacotherapeutic Potential of Aloe secundiflora against Colorectal Cancer Growth and Proliferation	114
Numerical Modeling of Particle Dynamics Inside a Dry Powder Inhaler	114
Solubility and Physical Stability Enhancement of Loratadine by Preparation of Co-Amorphous Solid Dispersion with Chlorpheniramine and Polyvinylpyrrolidone	113

Retinal Protection of New Nutraceutical Formulation	111
Antiviral Activity of Liposomes Containing Natural Compounds Against CHIKV	111
Enhancement and Limitations of Green-Spectrum Dual-Wavelength Irradiation in Porphyrin-Based Antimicrobial Strategies Targeting Cutibacterium acnes subsp. elongatum	110
Different Curcumin-Loaded Delivery Systems for Wound Healing Applications: A Comprehensive Review	110
Plant Nanovesicles for Essential Oil Delivery	110
UHPLC–MS/MS Method for the Simultaneous Quantification of 12 Antiretroviral Drugs in Human Plasma Using Dried Sample Spot Devices: Development, Validation, and Stability Evaluation	109
Fire in an Icy Desert: Oncolytic Virotherapy for Pancreatic Adenocarcinoma	108
Natural Lipid Extracts as an Artificial Membrane for Drug Permeability Assay: In Vitro and In Silico Characterization	108
Formulation and Evaluation of the In Vitro Performance of Topical Dermatological Products Containing Diclofenac Sodium	108
Nanomaterials-Incorporated Chemically Modified Gelatin Methacryloyl-Based Biomedical Composites: A Novel Approach for Bone Tissue Engineering	108
A Guide to Best Practice in Sensory Analysis of Pharmaceutical Formulations	107
AChE Inhibition Capability of Nanogels Derived from Natural Molecules: Tannic Acid and Lysine for Alzheimer’s Disease	106
Nanoparticle-Mediated Nose-to-Brain Delivery for Ischemic Stroke Therapy: Preclinical Insights	105
Dendrimers and Derivatives as Multifunctional Nanotherapeutics for Alzheimer’s Disease	105
The Antimicrobial Potency of Mesoporous Silica Nanoparticles Loaded with Melissa officinalis Extract	105
Antimicrobial Nano-Zinc Oxide Biocomposites for Wound Healing Applications: A Review	104
Plasma Cell Myeloma: Biochemical Insights into Diagnosis, Treatment, and Smart Nanocarrier-Based Therapeutic Development	103
Targeted Nanocarrier Delivery of RNA Therapeutics to Control HIV Infection	102
Nanoscale Delivery Systems of Lutein: An Updated Review from a Pharmaceutical Perspective	101
pH-Triggered Controlled Release of Chlorhexidine Using Chitosan-Coated Titanium Silica Composite for Dental Infection Prevention	101
Physicochemical and Stability Evaluation of Topical Niosomal Encapsulating Fosinopril/γ-Cyclodextrin Complex for Ocular Delivery	100
The Potential of the Nose-to-Brain Delivery of PACAP for the Treatment of Neuronal Disease	100
Enhanced Efinaconazole Permeation and Activity Against Trichophyton rubrum and Trichophyton mentagrophytes with a Self-Nanoemulsifying Drug Delivery System	100
Studies on the Interaction between Model Proteins and Fluorinated Ionic Liquids	100
Advances in Drug Delivery Integrated with Regenerative Medicine: Innovations, Challenges, and Future Frontiers	99
A Degradable Nanosystem Based on Small Gold Nanoparticles and Albumin for Amyloid Aggregation Inhibition	99