Genes & Genomics

Article	Citations
Comparison between MGI and Illumina sequencing platforms for whole genome sequencing	44
Molecular subtypes of triple-negative breast cancer: understanding of subtype categories and clinical implication	23
The tissue expression of MCT3, MCT8, and MCT9 genes in women with breast cancer	20
Mesenchymal stem cell-derived exosome mir-342-3p inhibits metastasis and chemo-resistance of breast cancer through regulating ID4	17
LINC00943 knockdown exerts neuroprotective effects in Parkinson’s disease through regulates CXCL12 expression by sponging miR-7-5p	16
Epigenome editing: targeted manipulation of epigenetic modifications in plants	16
EGR1 promotes stemness and predicts a poor outcome of uterine cervical cancer by inducing SOX9 expression	16
YTHDF1 promotes the proliferation, migration, and invasion of prostate cancer cells by regulating TRIM44	16
Knockdown of circPUM1 impedes cell growth, metastasis and glycolysis of papillary thyroid cancer via enhancing MAPK1 expression by serving as the sponge of miR-21-5p	15
Bulk segregant analysis identifies SSR markers associated with leaf- and seed-related traits in Perilla crop (Perilla frutescens L.)	15
Epigenetic control of abiotic stress signaling in plants	14
Metagenomics analysis of the gut microbiome in healthy and bacterial pneumonia forest musk deer	14
DNA methylation and histone modifications induced by abiotic stressors in plants	14
Genetic characterization and association mapping in near-isogenic lines of waxy maize using seed characteristics and SSR markers	14
Emerging roles of centromeric RNAs in centromere formation and function	13
Dynamic evolution of Panax species	13
LncRNA HOTAIRM1 knockdown inhibits cell glycolysis metabolism and tumor progression by miR-498/ABCE1 axis in non‐small cell lung cancer	13
Using weighted gene co-expression network analysis (WGCNA) to identify the hub genes related to hypoxic adaptation in yak (Bos grunniens)	12
Long non-coding RNA HOTAIR promotes hepatocellular carcinoma progression by regulating miR-526b-3p/DHX33 axis	12
SIRT3-mediated mitochondrial unfolded protein response weakens breast cancer sensitivity to cisplatin	12
Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells	12
Inhibition of FOSL2 aggravates the apoptosis of ovarian cancer cells by promoting the formation of inflammasomes	11
Comparative FISH analysis of Senna tora tandem repeats revealed insights into the chromosome dynamics in Senna	11
Reduced fertility caused by meiotic defects and micronuclei formation during microsporogenesis in xBrassicoraphanus	11
Transcriptome profiling of olive flounder responses under acute and chronic heat stress	11

microRNA profiles of serum exosomes derived from children with nonalcoholic fatty liver	10
Paeoniflorin reduces the inflammatory response of THP-1 cells by up‐regulating microRNA-124	10
Long non-coding RNA NEAT1 promotes lipopolysaccharide-induced acute lung injury by regulating miR-424-5p/MAPK14 axis	10
Identification of a 193 bp promoter region of TaNRX1-D gene from common wheat that contributes to osmotic or ABA stress inducibility in transgenic Arabidopsis	10
Genome-wide association analysis for yield-related traits at the R6 stage in a Chinese soybean mini core collection	10
Causal relationship between smoking status, smoking frequency and bladder cancer: a Mendelian randomization study	10
Genome wide methylation analysis to uncover genes related to recurrent pregnancy loss	10
Inhibition of oxidative stress induced-cytotoxicity by coptisine in V79-4 Chinese hamster lung fibroblasts through the induction of Nrf-2 mediated HO-1 expression	10
Molecular sensors in the taste system of Drosophila	10
Recent advancement of NGS technologies to detect active transposable elements in plants	9
TFPI inhibits breast cancer progression by suppressing ERK/p38 MAPK signaling pathway	9
Research on the effect of interfering with miRNA-155 on triple-negative breast cancer cells	9
Protective effect of berberine chloride against cisplatin-induced ototoxicity	9
Transglutaminase 2 mediates transcriptional regulation through BAF250a polyamination	9
Glabridin attenuates atopic dermatitis progression through downregulating the TLR4/MyD88/NF-κB signaling pathway	9
BAIAP2L2 facilitates the malignancy of prostate cancer (PCa) via VEGF and apoptosis signaling pathways	9
CircRNA circ_0067772 aggravates the malignant progression of cutaneous squamous cell carcinoma by regulating miR-1238-3p/FOXG1 axis	9
SOX11-dependent CATSPER1 expression controls colon cancer cell growth through regulation the PI3K/AKT signaling pathway	9
LncRNA-GAS5/miR-382-3p axis inhibits pulmonary artery remodeling and promotes autophagy in chronic thromboembolic pulmonary hypertension	9
Diagnostic evaluation of qRT-PCR-based kit and dPCR-based kit for COVID-19	9
CircRNA_OTUD7A upregulates FOXP1 expression to facilitate the progression of diffuse large B-cell lymphoma via acting as a sponge of miR-431-5p	9
MiR-200c-3p inhibits LPS-induced M1 polarization of BV2 cells by targeting RIP2	8
missForest with feature selection using binary particle swarm optimization improves the imputation accuracy of continuous data	8
The role of exosomal miR-181b in the crosstalk between NSCLC cells and tumor-associated macrophages	8
Dysregulated lncRNA and mRNA may promote the progression of ischemic stroke via immune and inflammatory pathways: results from RNA sequencing and bioinformatics analysis	8
Association of APOE genotype with lipid profiles and type 2 diabetes mellitus in a Korean population	8
Relative synonymous codon usage of ORF1ab in SARS-CoV-2 and SARS-CoV	8
Genome-wide identification of GMP genes in Rosaceae and functional characterization of FaGMP4 in strawberry (Fragaria × ananassa)	8
MiR-137 inhibits the proliferation, invasion and migration of glioma via targeting to regulate EZH2	8
Genetic variation of seed oil characteristics in native Korean germplasm of Perilla crop (Perilla frutescens L.) using SSR markers	8
Mapping of QTL for agronomic traits using high-density SNPs with an RIL population in maize	8
LncRNA SNHG20 promotes cell proliferation and invasion by suppressing miR-217 in ovarian cancer	8
Circ_0001666 affects miR-620/WNK2 axis to inhibit breast cancer progression	8
Disheveled-associated activator of morphogenesis 2 promotes invasion of colorectal cancer by activating PAK1 and promoting MMP7 expression	8
Identification of MicroRNAs as potential biomarkers for detecting ischemic stroke	7
METTL3 m6A-dependently promotes miR-21-5p maturation to accelerate choriocarcinoma progression via the HIF1AN-induced inactivation of the HIF1A/VEGF pathway	7
Propofol enhanced the cell sensitivity to paclitaxel (PTX) in prostatic cancer (PC) through modulation of HOTAIR	7
Dissecting the meteorological and genetic factors affecting rice grain quality in Northeast China	7
Comparative analysis of human facial skin microbiome between topical sites compared to entire face	7
De novo genome assembly and annotation of Holothuria scabra (Jaeger, 1833) from nanopore sequencing reads	7
Genetic diversity and genetic differentiation of Megalobrama populations inferred by mitochondrial markers	7
Lactucin induces apoptosis through reactive oxygen species-mediated BCL-2 and CFLARL downregulation in Caki-1 cells	7
SsPsaH, a H subunit of the photosystem I reaction center of Suaeda salsa, confers the capacity of osmotic adjustment in tobacco	7
HIST1H2BN induced cell proliferation and EMT phenotype in prostate cancer via NF-κB signal pathway	7
Getting the chronological age out of DNA: using insights of age-dependent DNA methylation for forensic DNA applications	7
Overview of the betta fish genome regarding species radiation, parental care, behavioral aggression, and pigmentation model relevant to humans	7
Super‐resolution microscopy of genome organization	7
MiR-30c facilitates natural killer cell cytotoxicity to lung cancer through targeting GALNT7	7
Effect of human endogenous retrovirus-K env gene knockout on proliferation of ovarian cancer cells	7
Phylogeography of the Korean endemic Coreoleuciscus (Cypriniformes: Gobionidae): the genetic evidence of colonization through Eurasian continent to the Korean Peninsula during Late Plio-Pleistocene	6

Genetically predicted physical activity is associated with lower serum urate concentrations	6
LncRNA PVT1 influences breast cancer cells glycolysis through sponging miR-145-5p	6
Phosphofructokinase 1 platelet isoform induces PD-L1 expression to promote glioblastoma immune evasion	6
MiR-200c-3p aggravates gastric cell carcinoma via KLF6	6
The FvCYP714C2 gene plays an important role in gibberellin synthesis in the woodland strawberry	6
Suppression of HELLS by miR-451a represses mTOR pathway to hinder aggressiveness of SCLC	6
Genetic analysis and population genetic structure of hard-shelled mussel, Mytilus coruscus Gould 1861 (Mytiloida: Mytilidae) from the coasts of South Korea based on mitochondrial cytochrome oxidase (C	6
Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma	6
Transcriptome reveals genes involving in black skin color formation of ducks	6
Tumor suppressive effect of scavenger receptor class A member 5 overexpression in colorectal cancer by regulating PI3K/AKT/mTOR pathway	6
Autophagy induced by H. pylori VacA regulated the survival mechanism of the SGC7901 human gastric cancer cell line	6
Novel blood-based hypomethylation of SH3BP5 is associated with very early-stage lung adenocarcinoma	6
GAS5 regulates viability and apoptosis in TGF-β1-stimulated bronchial epithelial cells by regulating miR-217/HDAC4 axis	6
Massively parallel sequencing of 25 short tandem repeat loci including the SE33 marker in Koreans	6
Methyltransferase-like 3 (METTL3) mediated N6-methyladenosine (m6A) modifications facilitate mir-25-3p maturation to promote gastrointestinal stromal tumors (GISTs) progression	6
SmGDB: genome database of Salvia miltiorrhiza, an important TCM Plant	6
A genomic glimpse of B chromosomes in cichlids	6
The inflammatory signature in monocytes of Sjögren’s syndrome and systemic lupus erythematosus, revealed by the integrated Reactome and drug target analysis	6
Whole exome sequencing revealed novel variants in consanguineous Pakistani families with intellectual disability	6
Identification of HvLRX, a new dehydration and light responsive gene in Tibetan hulless barley (Hordeum vulgare var. nudum)	6
Expression of lncRNA NEAT1 in endometriosis and its biological functions in ectopic endometrial cells as mediated via miR-124-3p	6
Harnessing epigenetic variability for crop improvement: current status and future prospects	5
ox-LDL regulates proliferation and apoptosis in VSMCs by controlling the miR-183-5p/FOXO1	5
Identification of QTLs associated with the anaerobic germination potential using a set of Oryza nivara introgression lines	5
B3GNT3 acts as a carcinogenic factor in endometrial cancer via facilitating cell growth, invasion and migration through regulating RhoA/RAC1 pathway-associated markers	5
PLAGL2 increases adriamycin resistance and EMT in breast cancer cells by activating the Wnt pathway	5
Rab11a promotes the malignant progression of ovarian cancer by inducing autophagy	5
Role of lymphoid lineage cells aberrantly expressing alarmins S100A8/A9 in determining the severity of COVID-19	5
Knockdown of eIF3a attenuated cell growth in K1 human thyroid cancer cells	5
NEDD4L suppresses PD-L1 expression and enhances anti-tumor immune response in A549 cells	5
Spreading-dependent or independent Sir2-mediated gene silencing in budding yeast	5
In silico SARS-CoV-2 vaccine development for Omicron strain using reverse vaccinology	5
Comprehensive analysis of TCR repertoire of COVID-19 patients in different infected stage	5
Epigenetic reorganization during early embryonic lineage specification	5
Genome-wide identification of the ARRs gene family in tobacco (Nicotiana tabacum)	5
Defense responses of sulfur dioxygenase to sulfide stress in the razor clam Sinonovacula constricta	5
RNA sequencing reveals lncRNA-mediated non-mendelian inheritance of feather growth change in chickens	5
PVT1 knockdown inhibited the biological behavior of LPS-induced cardiac fibroblasts by regulating miR-24	5
Identification of DNA methylation and genetic alteration simultaneously from a single blood biopsy	5
Establishment and validation of five autophagy-related signatures for predicting survival and immune microenvironment in glioma	5
Rapid identification of SARS-CoV-2 in the point-of-care using digital PCR-based Dr. PCR™ Di20K COVID-19 Detection Kit without viral RNA extraction	5
Suppression of synuclein gamma inhibits the movability of endometrial carcinoma cells by PI3K/AKT/ERK signaling pathway	5
Bioinformatic and integrated analysis identifies an lncRNA–miRNA–mRNA interaction mechanism in gastric adenocarcinoma	5
Genotype–environment interaction for milk production of Gyr cattle in Brazil and Colombia	5
Development of EST-SSRs from the ark shell (Scapharca broughtonii) transcriptome and their application in genetic analysis of four populations	5
Neferine increases sensitivities to multiple anticancer drugs via downregulation of Bcl-2 expression in renal cancer cells	5
Ezh2 promotes TRβ lysine methylation-mediated degradation in hepatocellular carcinoma	5
Phosphoinositide-specific phospholipase C gene involved in heat and drought tolerance in wheat (Triticum aestivum L.)	5
Association of genetic variants of RNF213 with ischemic stroke risk in Koreans	5
Deubiquitinating enzyme Josephin-2 stabilizes PHGDH to promote a cancer stem cell phenotype in hepatocellular carcinoma	5
Knockdown of growth differentiation factor-15 inhibited nonsmall cell lung cancer through inactivating PTEN/PI3K/AKT signaling pathway	5
Berberine protects against palmitate induced beta cell injury via promoting mitophagy	5
Genome-wide DNA methylation profiling in differentiating Crohn’s disease from intestinal tuberculosis	5
Proteome based analysis of circulating SARS-CoV-2 variants: approach to a universal vaccine candidate	5
RPTOR methylation in the peripheral blood and breast cancer in the Chinese population	5
Rex: R-linked EXcel add-in for statistical analysis of medical and bioinformatics data	4
Transcriptome-wide characterization of the WRKY family genes in Lonicera macranthoides and the role of LmWRKY16 in plant senescence	4
Protocadherin alpha 3 inhibits lung squamous cell carcinoma metastasis and epithelial-mesenchymal transition	4
Effects of thymosin β4-derived peptides on migration and invasion of ovarian cancer cells	4
Thymidine decreases the DNA damage and apoptosis caused by tumor‐treating fields in cancer cell lines	4
Evaluation of human papillomavirus (HPV) genotyping assays using type-specific HPV L1 reference DNA	4
Forensic biogeographical ancestry inference: recent insights and current trends	4
FK866 inhibits colorectal cancer metastasis by reducing NAD+ levels in cancer-associated fibroblasts	4
Compound heterozygous mutations of NDUFV1 identified in a child with mitochondrial complex I deficiency	4
Phosphorylation of BIK1 is critical for interaction with downstream signaling components	4
Identification of three novel mutations in PCNT in vietnamese patients with microcephalic osteodysplastic primordial dwarfism type II	4
Genomic and transcriptomic analysis of Korean colorectal cancer patients	4
A fast and powerful aggregated Cauchy association test for joint analysis of multiple phenotypes	4
MicroRNA 452 regulates ASB8, NOL8, and CDR2 expression in colorectal cancer cells	4
Genetic polymorphism of HLA-DRA and alcohol consumption affect hepatitis development in the Korean population	4
ceRNA network of lncRNA MIR210HG/miR-377-3p/LMX1A in malignant proliferation of glioma cells	4
Verification of hotspots of genetic diversity in Korean population of Grateloupia asiatica and G. jejuensis (Rhodophyta) show low genetic diversity and similar geographic distribution	4
Concurrent classic driver oncogenes mutation with ROS1 rearrangement predicts superior clinical outcome in NSCLC patients	4
NINJ1 triggers extravillous trophoblast cell dysfunction through blocking the STAT3 signaling pathway	4
The complete mitochondrial genome of Hemigrapsus sinensis (Brachyura, Grapsoidea, Varunidae) and its phylogenetic position within Grapsoidea	4
LncSNHG3 promotes hepatocellular carcinoma epithelial mesenchymal transition progression through the miR-152-3p/JAK1 pathway	4
Identification and clinical characterization of Charcot-Marie-Tooth disease type 1C patients with LITAF p.G112S mutation	4
Correlation between recurrence of anorectal condyloma acuminatum and human papilloma virus subtype	4
VDR promotes testosterone synthesis in mouse Leydig cells via regulation of cholesterol side chain cleavage cytochrome P450 (Cyp11a1) expression	4
MiR-1299 functions as a tumor suppressor to inhibit the proliferation and metastasis of gastric cancer by targeting ARF6	4

Genome‐wide characterization and expression analysis of TOPP-type protein phosphatases in soybean (Glycine max L.) reveal the role of GmTOPP13 in drought tolerance	4
Differential expression and functional analysis of circRNA in the ovaries of Yili geese at different egg-laying stages	4
Transcriptional reprogramming caused by cold acclimation in Meloidogyne incognita eggs	4
Genome-wide identification of drought-responsive microRNAs and their target genes in Chinese jujube by deep sequencing	4
Diagnostic and therapeutic biomarkers for Alzheimer’s disease in human-derived platelets	4
MALAT1 knockdown promoted cell viability and migration of LPS-treated MG-63 cells via sponging miR-212	4
miR-582-5p inhibits migration and chemo-resistant capabilities of colorectal cancer cells by targeting TNKS2	4
Folate metabolizing gene polymorphisms and genetic vulnerability to preterm birth in Korean women	4
Naringenin ameliorates atopic dermatitis by inhibiting inflammation and enhancing immunity through the JAK2/STAT3 pathway	4
Comparative study of predicted miRNA between Indonesia and China (Wuhan) SARS-CoV-2: a bioinformatics analysis	4
Single-nucleus RNA sequencing reveals cell type-specific transcriptome alterations of Down syndrome hippocampus using the Dp16 mouse model	4
Genome sequencing and de novo and reference-based genome assemblies of Bos indicus breeds	4
Genetic mutations affecting mitochondrial function in cancer drug resistance	4
Trait − driven analysis of the 2p15p16.1 microdeletion syndrome suggests a complex pattern of interactions between candidate genes	4
Impact of VEGFA promoter polymorphisms on esophageal cancer risk in North-West Indians: a case-control study	4
Gene expression profiling and in vitro functional studies reveal RAD54L as a potential therapeutic target in multiple myeloma	4
VDR mediated HSD3B1 to regulate lipid metabolism and promoted testosterone synthesis in mouse Leydig cells	4
Comparing of backfat microRNAomes of Landrace and Neijiang pig by high-throughput sequencing	4
Genome-wide locus-specific DNA methylation repatterning may facilitate rapid evolution of mercury resistance in rice	4
Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation	4