OOIR: Observatory of International Research

Papers

(The TQCC of Genes & Genomics is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Trans-cinnamaldehyde protects C2C12 myoblasts from DNA damage, mitochondrial dysfunction and apoptosis caused by oxidative stress through inhibiting ROS production	40
Comparison between MGI and Illumina sequencing platforms for whole genome sequencing	34
Genome-wide association analysis reveals the genetic locus for high reproduction trait in Chinese Arbas Cashmere goat	29
Effects of p-coumaric acid on microRNA expression profiles in SNU-16 human gastric cancer cells	23
The C- and G-value paradox with polyploidy, repeatomes, introns, phenomes and cell economy	22
Molecular subtypes of triple-negative breast cancer: understanding of subtype categories and clinical implication	21
AbaR is a LuxR type regulator essential for motility and the formation of biofilm and pellicle in Acinetobacter baumannii	20
The tissue expression of MCT3, MCT8, and MCT9 genes in women with breast cancer	18
Alanyl-tRNA synthetase 1 (AARS1) gene mutation in a family with intermediate Charcot-Marie-Tooth neuropathy	17
LINC00657 knockdown suppresses hepatocellular carcinoma progression by sponging miR-424 to regulate PD-L1 expression	16
Knockdown of circPUM1 impedes cell growth, metastasis and glycolysis of papillary thyroid cancer via enhancing MAPK1 expression by serving as the sponge of miR-21-5p	15
Mesenchymal stem cell-derived exosome mir-342-3p inhibits metastasis and chemo-resistance of breast cancer through regulating ID4	15
Transcriptome analysis of metabolisms related to fruit cracking during ripening of a cracking-susceptible grape berry cv. Xiangfei (Vitis vinifera L.)	14
YTHDF1 promotes the proliferation, migration, and invasion of prostate cancer cells by regulating TRIM44	14
Differential expression profile of microRNA in yak skeletal muscle and adipose tissue during development	14
Molecular fossils “pseudogenes” as functional signature in biological system	14
Epigenome editing: targeted manipulation of epigenetic modifications in plants	13
EGR1 promotes stemness and predicts a poor outcome of uterine cervical cancer by inducing SOX9 expression	13
Proteostasis-associated aging: lessons from a Drosophila model	13
LINC00943 knockdown exerts neuroprotective effects in Parkinson’s disease through regulates CXCL12 expression by sponging miR-7-5p	13
Metagenomics analysis of the gut microbiome in healthy and bacterial pneumonia forest musk deer	13
Genome-wide analysis of LATERAL ORGAN BOUNDARIES DOMAIN-in Physcomitrella patens and stress responses	12
Using weighted gene co-expression network analysis (WGCNA) to identify the hub genes related to hypoxic adaptation in yak (Bos grunniens)	12
Dynamic evolution of Panax species	12
The SnRK2 family in pepper (Capsicum annuum L.): genome-wide identification and expression analyses during fruit development and under abiotic stress	12

Bulk segregant analysis identifies SSR markers associated with leaf- and seed-related traits in Perilla crop (Perilla frutescens L.)	12
Long non-coding RNA HOTAIR promotes hepatocellular carcinoma progression by regulating miR-526b-3p/DHX33 axis	12
Cellular and molecular mechanisms of DEET toxicity and disease-carrying insect vectors: a review	12
MiR-339 attenuates LPS-induced intestinal epithelial cells inflammatory responses and apoptosis by targeting TLR4	11
DNA methylation and histone modifications induced by abiotic stressors in plants	11
Genetic characterization and association mapping in near-isogenic lines of waxy maize using seed characteristics and SSR markers	11
Tip60 and p300 function antagonistically in the epigenetic regulation of HPV18 E6/E7 genes in cervical cancer HeLa cells	11
Genome-wide identification of microRNAs and phased siRNAs in soybean roots under long-term salt stress	11
LncRNA A2M-AS1 lessens the injury of cardiomyocytes caused by hypoxia and reoxygenation via regulating IL1R2	11
Emerging roles of centromeric RNAs in centromere formation and function	10
LncRNA HOTAIRM1 knockdown inhibits cell glycolysis metabolism and tumor progression by miR-498/ABCE1 axis in non‐small cell lung cancer	10
Epigenetic control of abiotic stress signaling in plants	10
Identifying genes for resistant starch, slowly digestible starch, and rapidly digestible starch in rice using genome-wide association studies	10
Identification of a 193 bp promoter region of TaNRX1-D gene from common wheat that contributes to osmotic or ABA stress inducibility in transgenic Arabidopsis	9
MicroRNA-34a inhibits cell invasion and epithelial-mesenchymal transition via targeting AXL/PI3K/AKT/Snail signaling in nasopharyngeal carcinoma	9
Comparative FISH analysis of Senna tora tandem repeats revealed insights into the chromosome dynamics in Senna	9
Assessment of genetic diversity and population structure among a collection of Korean Perilla germplasms based on SSR markers	9
SIRT3-mediated mitochondrial unfolded protein response weakens breast cancer sensitivity to cisplatin	9
miRNAs-dependent regulation of synapse formation and function	9
Genome wide methylation analysis to uncover genes related to recurrent pregnancy loss	9
Recent advancement of NGS technologies to detect active transposable elements in plants	9
Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells	9
Suppression of long non-coding RNA PCAT19 inhibits glioma cell proliferation and invasion, and increases cell apoptosis through regulation of MELK targeted by miR-142-5p	9
The Tim gene family in efferocytosis	9
Inhibition of oxidative stress induced-cytotoxicity by coptisine in V79-4 Chinese hamster lung fibroblasts through the induction of Nrf-2 mediated HO-1 expression	9
Genome-wide association analysis for yield-related traits at the R6 stage in a Chinese soybean mini core collection	9
Gamma linolenic acid suppresses hypoxia-induced proliferation and invasion of non-small cell lung cancer cells by inhibition of HIF1α	9
Transcriptome sequencing and characterization of Astragalus membranaceus var. mongholicus root reveals key genes involved in flavonoids biosynthesis	9
The impact of TNFSF14 on prognosis and immune microenvironment in clear cell renal cell carcinoma	9
LncRNA-GAS5/miR-382-3p axis inhibits pulmonary artery remodeling and promotes autophagy in chronic thromboembolic pulmonary hypertension	8
Diagnostic evaluation of qRT-PCR-based kit and dPCR-based kit for COVID-19	8
Transcriptome profiling of olive flounder responses under acute and chronic heat stress	8
MiR-137 inhibits the proliferation, invasion and migration of glioma via targeting to regulate EZH2	8
Glabridin attenuates atopic dermatitis progression through downregulating the TLR4/MyD88/NF-κB signaling pathway	8
CircRNA_OTUD7A upregulates FOXP1 expression to facilitate the progression of diffuse large B-cell lymphoma via acting as a sponge of miR-431-5p	8
Genome-wide identification of GMP genes in Rosaceae and functional characterization of FaGMP4 in strawberry (Fragaria × ananassa)	8
Transglutaminase 2 mediates transcriptional regulation through BAF250a polyamination	8
Comprehensive analysis of the expression and prognosis for TFAP2 in human lung carcinoma	8
Disheveled-associated activator of morphogenesis 2 promotes invasion of colorectal cancer by activating PAK1 and promoting MMP7 expression	8
Genome-wide characterization of simple sequence repeats in Palmae genomes	8
CircRNA circ_0067772 aggravates the malignant progression of cutaneous squamous cell carcinoma by regulating miR-1238-3p/FOXG1 axis	8
Reduced fertility caused by meiotic defects and micronuclei formation during microsporogenesis in xBrassicoraphanus	8
Paeoniflorin reduces the inflammatory response of THP-1 cells by up‐regulating microRNA-124	7
The role of exosomal miR-181b in the crosstalk between NSCLC cells and tumor-associated macrophages	7
Protective effect of berberine chloride against cisplatin-induced ototoxicity	7
BAIAP2L2 facilitates the malignancy of prostate cancer (PCa) via VEGF and apoptosis signaling pathways	7
Genome-wide insights of Ethiopian indigenous sheep populations reveal the population structure related to tail morphology and phylogeography	7
Causal relationship between smoking status, smoking frequency and bladder cancer: a Mendelian randomization study	7
Analysis of KAP1 expression patterns and human endogenous retrovirus Env proteins in ovarian cancer	7
microRNA profiles of serum exosomes derived from children with nonalcoholic fatty liver	7

TFPI inhibits breast cancer progression by suppressing ERK/p38 MAPK signaling pathway	7
Mapping of QTL for agronomic traits using high-density SNPs with an RIL population in maize	7
Super‐resolution microscopy of genome organization	7
Dissecting the meteorological and genetic factors affecting rice grain quality in Northeast China	7
SsPsaH, a H subunit of the photosystem I reaction center of Suaeda salsa, confers the capacity of osmotic adjustment in tobacco	7
Association between the IL-6, IL-10, and TNFα gene polymorphisms and preterm-birth in Korean women	7
Overview of the betta fish genome regarding species radiation, parental care, behavioral aggression, and pigmentation model relevant to humans	7
Association of APOE genotype with lipid profiles and type 2 diabetes mellitus in a Korean population	7
LncRNA SNHG20 promotes cell proliferation and invasion by suppressing miR-217 in ovarian cancer	7
Molecular characterization of Arabidopsis thaliana LSH1 and LSH2 genes	7
Comparative analysis of human facial skin microbiome between topical sites compared to entire face	7
SOX11-dependent CATSPER1 expression controls colon cancer cell growth through regulation the PI3K/AKT signaling pathway	6
Dysregulated lncRNA and mRNA may promote the progression of ischemic stroke via immune and inflammatory pathways: results from RNA sequencing and bioinformatics analysis	6
A novel nonsense mutation in NPR2 gene causing Acromesomelic dysplasia, type Maroteaux in a consanguineous family in Southern Punjab (Pakistan)	6
Identification of differentially expressed miRNAs after Lactobacillus reuteri treatment in the ileum mucosa of piglets	6
Suppression of HELLS by miR-451a represses mTOR pathway to hinder aggressiveness of SCLC	6
The role of CTNNB1 and LEF1 in feather follicles development of Anser cygnoides and Anser anser	6
Relative synonymous codon usage of ORF1ab in SARS-CoV-2 and SARS-CoV	6
missForest with feature selection using binary particle swarm optimization improves the imputation accuracy of continuous data	6
Autophagy induced by H. pylori VacA regulated the survival mechanism of the SGC7901 human gastric cancer cell line	6
Expression and evolution of the phospholipase C gene family in Brachypodium distachyon	6
Propofol enhanced the cell sensitivity to paclitaxel (PTX) in prostatic cancer (PC) through modulation of HOTAIR	6
Lactucin induces apoptosis through reactive oxygen species-mediated BCL-2 and CFLARL downregulation in Caki-1 cells	6
Molecular sensors in the taste system of Drosophila	6
Functional genomics by integrated analysis of transcriptome of sweet potato (Ipomoea batatas (L.) Lam.) during root formation	6
Long non-coding RNA NEAT1 promotes lipopolysaccharide-induced acute lung injury by regulating miR-424-5p/MAPK14 axis	6
Anti-infective nitazoxanide disrupts transcription of ribosome biogenesis-related genes in yeast	6
Comparative genomics of canine Lactobacillus reuteri reveals adaptation to a shared environment with humans	6
A genomic glimpse of B chromosomes in cichlids	6
Inhibition of FOSL2 aggravates the apoptosis of ovarian cancer cells by promoting the formation of inflammasomes	6
The characteristic of the synonymous codon usage and phylogenetic analysis of hepatitis B virus	6
Identification of HvLRX, a new dehydration and light responsive gene in Tibetan hulless barley (Hordeum vulgare var. nudum)	6
GAS5 regulates viability and apoptosis in TGF-β1-stimulated bronchial epithelial cells by regulating miR-217/HDAC4 axis	6
Genetic analysis and population genetic structure of hard-shelled mussel, Mytilus coruscus Gould 1861 (Mytiloida: Mytilidae) from the coasts of South Korea based on mitochondrial cytochrome oxidase (C	6
Expression of lncRNA NEAT1 in endometriosis and its biological functions in ectopic endometrial cells as mediated via miR-124-3p	6
Transcriptome reveals genes involving in black skin color formation of ducks	6
GEN2VCF: a converter for human genome imputation output format to VCF format	5
Identification of MicroRNAs as potential biomarkers for detecting ischemic stroke	5
Neferine increases sensitivities to multiple anticancer drugs via downregulation of Bcl-2 expression in renal cancer cells	5
Ezh2 promotes TRβ lysine methylation-mediated degradation in hepatocellular carcinoma	5
The inflammatory signature in monocytes of Sjögren’s syndrome and systemic lupus erythematosus, revealed by the integrated Reactome and drug target analysis	5
Circ_0001666 affects miR-620/WNK2 axis to inhibit breast cancer progression	5
A new perspective on biogeographic barrier in the flathead grey mullet (Pisces: Mugilidae) from the northwest Pacific	5
Methylation of CpG sites in C1QTNF1 (C1q and tumor necrosis factor related protein 1) differs by gender in acute coronary syndrome in Han population: a case–control study	5
Identification of DNA methylation and genetic alteration simultaneously from a single blood biopsy	5
Establishment and validation of five autophagy-related signatures for predicting survival and immune microenvironment in glioma	5
Research on the effect of interfering with miRNA-155 on triple-negative breast cancer cells	5
MiR-200c-3p inhibits LPS-induced M1 polarization of BV2 cells by targeting RIP2	5
Bioinformatic and integrated analysis identifies an lncRNA–miRNA–mRNA interaction mechanism in gastric adenocarcinoma	5
HIST1H2BN induced cell proliferation and EMT phenotype in prostate cancer via NF-κB signal pathway	5
ox-LDL regulates proliferation and apoptosis in VSMCs by controlling the miR-183-5p/FOXO1	5
MiR-30c facilitates natural killer cell cytotoxicity to lung cancer through targeting GALNT7	5
Tumor suppressive effect of scavenger receptor class A member 5 overexpression in colorectal cancer by regulating PI3K/AKT/mTOR pathway	5
B3GNT3 acts as a carcinogenic factor in endometrial cancer via facilitating cell growth, invasion and migration through regulating RhoA/RAC1 pathway-associated markers	5
MiR-200c-3p aggravates gastric cell carcinoma via KLF6	5
Estimation of C-derived introgression into A. m. mellifera colonies in the Russian Urals using microsatellite genotyping	5
Comparative transcriptomic and physiological analyses of contrasting hybrid cultivars ND476 and ZX978 identify important differentially expressed genes and pathways regulating drought stress tolerance	5
PVT1 knockdown inhibited the biological behavior of LPS-induced cardiac fibroblasts by regulating miR-24	5
Characterization and functional analysis of Krtap11-1 during hair follicle development in Angora rabbits (Oryctolagus cuniculus)	5
Comparative study of predicted miRNA between Indonesia and China (Wuhan) SARS-CoV-2: a bioinformatics analysis	5
Comparative analysis of the ovarian transcriptome reveals novel insights into fertility differences in Large White sows	5
Effect of human endogenous retrovirus-K env gene knockout on proliferation of ovarian cancer cells	5
Comprehensive analysis of TCR repertoire of COVID-19 patients in different infected stage	5
High-throughput sequencing analysis of differences in intestinal microflora between ulcerative colitis patients with different glucocorticoid response types	5
Identification of QTLs associated with the anaerobic germination potential using a set of Oryza nivara introgression lines	5
Protective mechanism of fdft1 in steroid hormone synthesis pathway in SD rats with acute hypoxic injury	5
Complete genome sequence of Sphingobium sp. strain PAMC 28499 reveals a potential for degrading pectin with comparative genomics approach	5
Association of genetic variants of RNF213 with ischemic stroke risk in Koreans	5
Novel blood-based hypomethylation of SH3BP5 is associated with very early-stage lung adenocarcinoma	5
METTL3 m6A-dependently promotes miR-21-5p maturation to accelerate choriocarcinoma progression via the HIF1AN-induced inactivation of the HIF1A/VEGF pathway	5
Genetic diversity and genetic differentiation of Megalobrama populations inferred by mitochondrial markers	5
The FvCYP714C2 gene plays an important role in gibberellin synthesis in the woodland strawberry	5
Rapid identification of SARS-CoV-2 in the point-of-care using digital PCR-based Dr. PCR™ Di20K COVID-19 Detection Kit without viral RNA extraction	5
Phylogeography of the Korean endemic Coreoleuciscus (Cypriniformes: Gobionidae): the genetic evidence of colonization through Eurasian continent to the Korean Peninsula during Late Plio-Pleistocene	5
Massively parallel sequencing of 25 short tandem repeat loci including the SE33 marker in Koreans	5