OOIR: Observatory of International Research

Papers

(The TQCC of Genes & Genomics is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Physiological and omics analysis of maize inbred lines during late grain development	32
OTOP3 functions as an oncogenic regulator of ferroptosis-mediated colorectal cancer progression	30
Profiling of testis-specific or testis-predominant genes expressed in mouse male germ cell lines GC-1 and GC-2	23
Postoperative circulating tumor DNA detection and CBLB mutations are prognostic biomarkers for gastric cancer	21
Phosphofructokinase 1 platelet isoform induces PD-L1 expression to promote glioblastoma immune evasion	19
DNA methylome profiling of blood to identify individuals in a pair of monozygotic twins	18
UBL4A as a suppressor of intracerebral hemorrhage by binding to MAPK14 and promoting MAPK14 ubiquitination	18
Gut Microbiome and colorectal cancer: discovery of bacterial changes with metagenomics application in Turkısh population	17
Association mapping analysis (AMA) for morpho-agronomic traits and leaf aromatic compounds using SSR markers in three types of Perilla crop collected from South Korea	16
Development of markers using microsatellite loci of two rove beetle species, Paederus fuscipes Curtis and Aleochara (Aleochara) curtula Goeze (Coleoptera: Staphylinidae), followed by analyses of genet	16
Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation	16
A rare TNNT1 gene variant causing creatine kinase elevation in nemaline myopathy: c.271_273del (p.Lys91del)	16
UBE2C regulating the lung carcinoma progression via inhibiting ubiquitin-proteasomal degradation to increase MMP9 protein stability	15
Tumor microenvironment-driven drug resistance in urologic cancers: mechanisms and therapeutic targets	15
Comparative whole genome analysis of face-derived Streptococcus infantis CX-4 unravels the functions related to skin barrier	15
Discovery and genome-wide characterization of a novel miniature inverted repeat transposable element reveal genome-specific distribution in Glycine	15
RNA-binding protein expression based machine learning model predicts metastasis and treatment outcome of testicular cancer	15
FK866 inhibits colorectal cancer metastasis by reducing NAD+ levels in cancer-associated fibroblasts	14
Correlation between obstructive sleep apnea and cerebral small vessel disease: a mendelian randomization study	14
Knockdown of growth differentiation factor-15 inhibited nonsmall cell lung cancer through inactivating PTEN/PI3K/AKT signaling pathway	14
Targeting phosphofructokinase 2 the isoform PFKFB4 suppresses glioblastoma proliferation and malignancy	13
Whole-genome sequencing revealed different demographic histories among the Korean endemic hill pigeon (Columba rupestris), rock pigeon (Columba livia var. domestica) and oriental turtle dove (Streptop	12
Comparative analysis of spatial expression patterns of ectopic olfactory receptors	12
Itaconate modulates myeloid inflammation in myocardial infarction via metabolic and structural reprogramming	12
Hierarchical structural component model for pathway analysis of multinomial phenotypes	12

m6A-mediated lncRNA NEAT1 plays an oncogenic role in non-small cell lung cancer by upregulating the HMGA1 expression through binding miR-361-3p	12
Extracellular nicotinamide phosphoribosyltransferase visfatin activates JAK2-STAT3 pathway in cancer-associated fibroblasts to promote colorectal cancer metastasis	12
Glycolytic-inflammatory crosstalk mediated by Glyco-PMF-Rux hub genes drives PMF progression and ruxolitinib resistance	12
Feature selection for effective prediction of SARS-COV-2 using machine learning	12
Genome-wide DNA methylation analysis in schizophrenia with tardive dyskinesia: a preliminary study	12
Complete genome sequence of the Pogostemon cablin bacterial wilt pathogen Ralstonia solanacearum strain SY1	11
Digital insights into Pseudomonas aeruginosa PBH03: in-silico analysis for genomic toolbox and unraveling cues for heavy metal bioremediation	11
In-silico matching of SARS-CoV-2 genes and oligonucleotides using the Simple Oligo Matching Tool	11
Discovery of high-expressing lncRNA-derived sORFs as potential tumor-associated antigens in hepatocellular carcinoma	11
Analysis of evolutionary and genetic patterns in structural genes of primate lentiviruses	10
Deciphering the molecular landscape of hepatopancreatic necrosis disease in Eriocheir sinensis using RNA-Seq meta-analysis	10
Description of the whole mitochondrial genome of Bhatia longiradiata (Hemiptera, Cicadellidae, Deltocephalinae: Drabescini) and phylogenetic relationship	10
Whole exome sequencing of 80 cases of sporadic mitral valve prolapse reveals novel disease-associated genes and variants in a Southern Chinese population	10
STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells	10
Transcriptome analysis of response strategy in Hemerocallis fulva under drought stress	10
Identification of DNA methylation and genetic alteration simultaneously from a single blood biopsy	10
The impact of histone lactylation on the tumor microenvironment and metabolic pathways and its potential in cancer therapy	9
Correction: Suppression of synuclein gamma inhibits the movability of endometrial carcinoma cells by PI3K/AKT/ERK signaling pathway	9
Weighted gene co-expression network analysis and identification of ginsenoside biosynthesis candidate genes for ginseng adventitious roots under MeJA treatment	9
Comparative analysis of cancer gene mutations using targeted sequencing in matched primary and recurrent gastric cancers after chemotherapy	9
SEMA4A promotes acute myeloid leukemia progression through inhibiting apoptosis	9
c-Jun N-terminal kinase 1 (JNK1) phosphorylates OTX2 transcription factor that regulates early retinal development	9
In silico identification and expression analysis of superoxide dismutases in Tenebrio molitor	9
c-Myc regulated long noncoding RNA TRD-AS1 to affect the progression of oral squamous cell carcinoma	9
Characterization of the complete mitogenome of the endangered freshwater fish Gobiobotia naktongensis from the Geum River in South Korea: evidence of stream connection with the Paleo-Huanghe	9
RNA sequencing reveals lncRNA-mediated non-mendelian inheritance of feather growth change in chickens	9
A new Korean genotype of bluegill Lepomis macrochirus (Centrarchidae) covering the Korean Peninsula: insights for management of an introduced freshwater fish	9
Decoding splicing complexity: integrated genomic analysis reveals two novel pathogenic variants in Chinese dystrophinopathy pedigrees	9
Lasting bone marrow defects imprinted by hyperglycemia shape the immunological characteristics of differentiated M1 and M2 macrophages	8
Getting the chronological age out of DNA: using insights of age-dependent DNA methylation for forensic DNA applications	8
Clariid catfish hybridization in aquaculture: a comprehensive review of strategies, challenges, and future directions	8
The role of RANBP1 in regulating MiRNA expression and apoptosis in breast cancer cells	8
Genetic association study identifies genetic variants for non-alcoholic fatty liver without comorbidities in the Korean population	8
ADP-glucose pyrophosphorylase gene family in soybean and implications in drought stress tolerance	8
High-throughput data on circular RNA reveal novel insights into chronic glomerulonephritis	8
Comparison of unique Dong Tao chickens from Vietnam and Thailand: genetic background and differences for resource management	8
Kernel-based hierarchical structural component models for pathway analysis on survival phenotype	7
Four mutations identified in Chinese families with autosomal dominant congenital cataracts by next-generation sequencing	7
Genome-wide analysis of the potato GRF gene family and their expression profiles in response to hormone and Ralstonia solanacearum infection	7
Assembly of a high-quality Polypterus senegalus diploid genome	7
Differential expression and functional analysis of circRNA in the ovaries of Yili geese at different egg-laying stages	7
Transcriptomic analysis of neutrophil apoptosis induced by diffuse large B-cell lymphoma unveils a potential role in neutropenia	7
Emerging technologies and clinical translation of urine-based liquid biopsy in urological cancers	7
METTL3 m6A-dependently promotes miR-21-5p maturation to accelerate choriocarcinoma progression via the HIF1AN-induced inactivation of the HIF1A/VEGF pathway	7
Identification of a novel prognostic signature composed of 3 cuproptosis-related transcription factors in colon adenocarcinoma	7
Novel citrivirus and prunevirus genomes further demonstrate the recurrent, independent acquisition of nucleic acid-binding proteins in the family Betaflexiviridae	7
Genome-wide identification of the valine-glutamine motif containing gene family and the role of VQ25-1 in pollen germination in Brassica oleracea	7
Comprehensive assessment of the significance of cellular senescence-associated genes in neuroblastoma	7
Resolving repetitive and telomeric regions through a high-contiguity genome assembly of the African Turquoise killifish	7
Identification of novel CDH23 heterozygous variants causing autosomal recessive nonsyndromic hearing loss	7

Role of tyrosine autophosphorylation and methionine residues in BRI1 function in Arabidopsis thaliana	7
A novel duplication mutation in the MYO7A gene associated with autosomal recessive hearing loss in a Chinese family	7
Characteristics of insulin resistance in Korean adults from the perspective of circadian and metabolic sensing genes	7
Genomic analyses of intricate interaction of TE-lncRNA overlapping genes with miRNAs in human diseases	7
Identification of Saccharum CaM gene family and function characterization of ScCaM1 during cold and oxidant exposure in Pichia pastoris	6
Current issues in forensic genetics	6
LncRNA KTN1-AS1 facilitates esophageal squamous cell carcinoma progression via miR-885-5p/STRN3 axis	6
The coefficients of inbreeding revealed by ROH study among inbred individuals belonging to each type of the first cousin marriage: A preliminary report from North India	6
Histone lactatation-related genes GPR19 and SLC22A16 are important diagnostic markers and drug treatment targets for prostate cancer	6
Perillic acid disrupts the specification of germ layers by upregulating the FGF/MAPK pathway	6
Berberine protects against palmitate induced beta cell injury via promoting mitophagy	6
Integrative transcriptomics defines CD36 as a key regulator of immunometabolic signaling in acute myeloid leukemia	6
Prevalence of germline 113 cancer genes in healthy Indonesian hospital staff	6
Genome-wide identification of drought-responsive microRNAs and their target genes in Chinese jujube by deep sequencing	6
Integrated analysis identifies conserved transcription factors TCF12, E2F1, and TEAD4 with diagnostic and therapeutic value in osteoarthritis subchondral bone	6
Gene expression profile in ulcerative colitis patients: FOXO4, ALDOB, SLC26A3, SOD2 genes as potential biomarkers	6
Transcriptome analysis reveals genes connected to temperature adaptation in juvenile antarctic krill Euphausia superba	6
Human umbilical cord mesenchymal stem cells overexpressing RUNX1 promote tendon-bone healing by inhibiting osteolysis, enhancing osteogenesis and promoting angiogenesis	6
Transcriptional induction of TGF-β1 and endothelial-to-mesenchymal transition cell markers in human umbilical vein endothelial cells by Ebola virus infection	6
A novel approach of kinship determination based on the physical length of genetically shared regions of chromosomes	6
A novel pathogenic deletion in ISPD causes Walker-Warburg syndrome in a Chinese family	6
Selection of heat stress-tolerant cultivars from radish and analysis of gene expression under high-temperature	6
A novel role of the cotton calcium sensor CBL3 was involved in Verticillium wilt resistance in cotton	6
P14.5 functions to inhibit cell migration and can be used as a prognostic marker in hepatocellular carcinoma	6
Comparative analysis of VMT genes/proteins in selected plant species with emphasis on bread wheat (Triticum aestivum L.)	6
Ectopic expression of AtMYB115 and AtMYB118 induces green tissue formation in non-green organs of Arabidopsis thaliana	6
Full-length transcriptome combined with RNA sequence analysis of Fraxinus chinensis	6
Single-cell transcriptomic analysis reveals transcriptional and cell subpopulation differences between human and pig immune cells	6
MicroRNA-124 induces AML differentiation and apoptosis through c-Myc suppression	6
Pathogenicity analysis and functional prediction of a rare LDLR variant in familial hypercholesterolemia combined with Wilson disease	6
A novel study on CXXC5: unraveling its regulatory mechanisms in hematopoietic stem cell biology through proteomics and gene editing	6
miR-214-3p inhibits LPS-induced macrophage inflammation and attenuates the progression of dry eye syndrome by regulating ferroptosis in cells	6
Clinical and genetic analyses in syndromic intellectual disability with primary microcephaly reveal biallelic and de novo variants in patients with parental consanguinity	6
Genome-wide identification and expression analysis of the Hsf gene family in Rhododendron molle under heat stress	5
Characterization and comparative analysis of the complete organelle genomes of three red macroalgae species (Neoporphyra dentata, Neoporphyra seriata, and Neopyropia yezoensis) and development of mole	5
Population genetics reveals new introgression in the nucleus herd of min pigs	5
Complete mitochondrial genome of the Chinese Callipogon (Eoxenus) relictus (Cerambycidae: Prioninae) with phylogenetic analyses	5
Genetic variation of seed oil characteristics in native Korean germplasm of Perilla crop (Perilla frutescens L.) using SSR markers	5
Triptonide suppresses the FOXK1/AKT2 axis to reverse malignant phenotype and improve cisplatin efficacy in esophageal squamous cell carcinoma	5
Disclosing the hidden nucleotide sequences: a journey into DNA barcoding of raptor species in public repositories	5
Establishment of a novel myocarditis mouse model based on cyclosporine A	5
Role of Brassica rapa SWEET genes in the defense response to Plasmodiophora brassicae	5
A comparative investigation of single nucleotide variant calling for a personal non-Caucasian sequencing sample	5
Molecular cloning, expression analysis, and functional characterization of Intelectin-1 from Chinese giant salamanders (Andrias davidianus)	5
Transcriptomic profiling of the cold stress and recovery responsiveness of two contrasting Guizhou HE rice genotypes	5
Mmu_circ_0000271 regulated the growth of ox-LDL-stimulated mouse vascular smooth muscle cells via sponging miR-5123	5
Overexpression of TRIM44 mediates the NF-κB pathway to promote the progression of ovarian cancer	5
Salivary amylase gene (AMY1) copy number variation has only a minor correlation with body composition in Chinese adults	5
Optimizing Bangkaew dog breed identification using DNA technology	5
Identification of Feronia-interacting proteins in Arabidopsis thaliana	5
Cryptic diversity and population genetic structure of the mantis shrimp Oratosquilla oratoria in South Korea	5
Pitfalls of whole exome sequencing in undefined clinical conditions with a suspected genetic etiology	5