OOIR: Observatory of International Research

Papers

(The TQCC of Genes & Genomics is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation	27
Postoperative circulating tumor DNA detection and CBLB mutations are prognostic biomarkers for gastric cancer	22
Phosphofructokinase 1 platelet isoform induces PD-L1 expression to promote glioblastoma immune evasion	21
DNA methylome profiling of blood to identify individuals in a pair of monozygotic twins	21
Association mapping analysis (AMA) for morpho-agronomic traits and leaf aromatic compounds using SSR markers in three types of Perilla crop collected from South Korea	20
Profiling of testis-specific or testis-predominant genes expressed in mouse male germ cell lines GC-1 and GC-2	20
Epigenetic reorganization during early embryonic lineage specification	17
Physiological and omics analysis of maize inbred lines during late grain development	16
Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma	16
A rare TNNT1 gene variant causing creatine kinase elevation in nemaline myopathy: c.271_273del (p.Lys91del)	15
Gut Microbiome and colorectal cancer: discovery of bacterial changes with metagenomics application in Turkısh population	15
Phylogeography of the Korean endemic Coreoleuciscus (Cypriniformes: Gobionidae): the genetic evidence of colonization through Eurasian continent to the Korean Peninsula during Late Plio-Pleistocene	15
Correlation between obstructive sleep apnea and cerebral small vessel disease: a mendelian randomization study	14
LncRNA SNHG20 promotes cell proliferation and invasion by suppressing miR-217 in ovarian cancer	14
Development of markers using microsatellite loci of two rove beetle species, Paederus fuscipes Curtis and Aleochara (Aleochara) curtula Goeze (Coleoptera: Staphylinidae), followed by analyses of genet	14
NEDD4L suppresses PD-L1 expression and enhances anti-tumor immune response in A549 cells	14
Comparative whole genome analysis of face-derived Streptococcus infantis CX-4 unravels the functions related to skin barrier	12
Discovery and genome-wide characterization of a novel miniature inverted repeat transposable element reveal genome-specific distribution in Glycine	12
RNA-binding protein expression based machine learning model predicts metastasis and treatment outcome of testicular cancer	11
Transcriptomic analysis reveal the responses of dendritic cells to VDBP	11
ICT1 deficiency leads to reduced oxygen resistance due to the cell wall damage in S. cerevisiae	11
UBE2C regulating the lung carcinoma progression via inhibiting ubiquitin-proteasomal degradation to increase MMP9 protein stability	11
FK866 inhibits colorectal cancer metastasis by reducing NAD+ levels in cancer-associated fibroblasts	10
SIRT3-mediated mitochondrial unfolded protein response weakens breast cancer sensitivity to cisplatin	10
Lactucin induces apoptosis through reactive oxygen species-mediated BCL-2 and CFLARL downregulation in Caki-1 cells	10

m6A-mediated lncRNA NEAT1 plays an oncogenic role in non-small cell lung cancer by upregulating the HMGA1 expression through binding miR-361-3p	10
Rapid identification of SARS-CoV-2 in the point-of-care using digital PCR-based Dr. PCR™ Di20K COVID-19 Detection Kit without viral RNA extraction	10
Prospects and challenges of epigenomics in crop improvement	9
Genome-wide DNA methylation analysis in schizophrenia with tardive dyskinesia: a preliminary study	9
Whole-genome sequencing revealed different demographic histories among the Korean endemic hill pigeon (Columba rupestris), rock pigeon (Columba livia var. domestica) and oriental turtle dove (Streptop	9
Knockdown of growth differentiation factor-15 inhibited nonsmall cell lung cancer through inactivating PTEN/PI3K/AKT signaling pathway	9
Identification of novel candidate genes implicated in odontogenic potential in the developing mouse tooth germ using transcriptome analysis	9
MicroRNA-9 inhibits proliferation and progression in retinoblastoma cells by targeting PTEN	9
Extracellular nicotinamide phosphoribosyltransferase visfatin activates JAK2-STAT3 pathway in cancer-associated fibroblasts to promote colorectal cancer metastasis	9
Characterization of the complete mitogenome of the endangered freshwater fish Gobiobotia naktongensis from the Geum River in South Korea: evidence of stream connection with the Paleo-Huanghe	9
The impact of histone lactylation on the tumor microenvironment and metabolic pathways and its potential in cancer therapy	8
High-throughput data on circular RNA reveal novel insights into chronic glomerulonephritis	8
Feature selection for effective prediction of SARS-COV-2 using machine learning	8
Digital insights into Pseudomonas aeruginosa PBH03: in-silico analysis for genomic toolbox and unraveling cues for heavy metal bioremediation	8
Identification of DNA methylation and genetic alteration simultaneously from a single blood biopsy	8
Complete genome sequence of the Pogostemon cablin bacterial wilt pathogen Ralstonia solanacearum strain SY1	8
c-Jun N-terminal kinase 1 (JNK1) phosphorylates OTX2 transcription factor that regulates early retinal development	8
Towards fine-scale population stratification modeling based on kernel principal component analysis and random forest	8
Discovery of high-expressing lncRNA-derived sORFs as potential tumor-associated antigens in hepatocellular carcinoma	8
Whole exome sequencing of 80 cases of sporadic mitral valve prolapse reveals novel disease-associated genes and variants in a Southern Chinese population	8
Description of the whole mitochondrial genome of Bhatia longiradiata (Hemiptera, Cicadellidae, Deltocephalinae: Drabescini) and phylogenetic relationship	8
Analysis of evolutionary and genetic patterns in structural genes of primate lentiviruses	8
Transcriptome analysis of response strategy in Hemerocallis fulva under drought stress	8
Genetic diversity and genetic differentiation of Megalobrama populations inferred by mitochondrial markers	8
STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells	8
CALM1 rs3179089 polymorphism might contribute to coronary artery disease susceptibility in Chinese male: a case–control study	8
ADP-glucose pyrophosphorylase gene family in soybean and implications in drought stress tolerance	7
Genome-wide locus-specific DNA methylation repatterning may facilitate rapid evolution of mercury resistance in rice	7
Identification of novel CDH23 heterozygous variants causing autosomal recessive nonsyndromic hearing loss	7
Novel blood-based hypomethylation of SH3BP5 is associated with very early-stage lung adenocarcinoma	7
miR-582-5p inhibits migration and chemo-resistant capabilities of colorectal cancer cells by targeting TNKS2	7
Comparison of unique Dong Tao chickens from Vietnam and Thailand: genetic background and differences for resource management	7
VDR mediated HSD3B1 to regulate lipid metabolism and promoted testosterone synthesis in mouse Leydig cells	7
Kernel-based hierarchical structural component models for pathway analysis on survival phenotype	7
Comparative analysis of cancer gene mutations using targeted sequencing in matched primary and recurrent gastric cancers after chemotherapy	7
In silico identification and expression analysis of superoxide dismutases in Tenebrio molitor	7
METTL3 m6A-dependently promotes miR-21-5p maturation to accelerate choriocarcinoma progression via the HIF1AN-induced inactivation of the HIF1A/VEGF pathway	7
Tumor suppressive effect of scavenger receptor class A member 5 overexpression in colorectal cancer by regulating PI3K/AKT/mTOR pathway	7
RNA sequencing reveals lncRNA-mediated non-mendelian inheritance of feather growth change in chickens	7
Weighted gene co-expression network analysis and identification of ginsenoside biosynthesis candidate genes for ginseng adventitious roots under MeJA treatment	7
Correction: Suppression of synuclein gamma inhibits the movability of endometrial carcinoma cells by PI3K/AKT/ERK signaling pathway	7
Genetic association study identifies genetic variants for non-alcoholic fatty liver without comorbidities in the Korean population	7
Getting the chronological age out of DNA: using insights of age-dependent DNA methylation for forensic DNA applications	7
Role of tyrosine autophosphorylation and methionine residues in BRI1 function in Arabidopsis thaliana	7
Identification of Saccharum CaM gene family and function characterization of ScCaM1 during cold and oxidant exposure in Pichia pastoris	6
LncRNA KTN1-AS1 facilitates esophageal squamous cell carcinoma progression via miR-885-5p/STRN3 axis	6
Single-cell transcriptomic analysis reveals transcriptional and cell subpopulation differences between human and pig immune cells	6
Transcriptomic analysis of neutrophil apoptosis induced by diffuse large B-cell lymphoma unveils a potential role in neutropenia	6
Four mutations identified in Chinese families with autosomal dominant congenital cataracts by next-generation sequencing	6
Characteristics of insulin resistance in Korean adults from the perspective of circadian and metabolic sensing genes	6

Clinical and genetic analyses in syndromic intellectual disability with primary microcephaly reveal biallelic and de novo variants in patients with parental consanguinity	6
PKC-β modulates Ca2+ mobilization through Stim1 phosphorylation	6
RPTOR methylation in the peripheral blood and breast cancer in the Chinese population	6
Identification a novel de novo RUNX2 frameshift mutation associated with cleidocranial dysplasia	6
A novel role of the cotton calcium sensor CBL3 was involved in Verticillium wilt resistance in cotton	6
Differential expression and functional analysis of circRNA in the ovaries of Yili geese at different egg-laying stages	6
Genome-wide analysis of the potato GRF gene family and their expression profiles in response to hormone and Ralstonia solanacearum infection	6
Identification of a novel prognostic signature composed of 3 cuproptosis-related transcription factors in colon adenocarcinoma	6
Genome-wide identification of drought-responsive microRNAs and their target genes in Chinese jujube by deep sequencing	6
Neferine increases sensitivities to multiple anticancer drugs via downregulation of Bcl-2 expression in renal cancer cells	6
Human umbilical cord mesenchymal stem cells overexpressing RUNX1 promote tendon-bone healing by inhibiting osteolysis, enhancing osteogenesis and promoting angiogenesis	6
Comparative analysis of human facial skin microbiome between topical sites compared to entire face	6
Genomic analyses of intricate interaction of TE-lncRNA overlapping genes with miRNAs in human diseases	6
miR-214-3p inhibits LPS-induced macrophage inflammation and attenuates the progression of dry eye syndrome by regulating ferroptosis in cells	6
Genome-wide identification of the valine-glutamine motif containing gene family and the role of VQ25-1 in pollen germination in Brassica oleracea	6
Gene expression profile in ulcerative colitis patients: FOXO4, ALDOB, SLC26A3, SOD2 genes as potential biomarkers	6
Ectopic expression of AtMYB115 and AtMYB118 induces green tissue formation in non-green organs of Arabidopsis thaliana	6
A novel study on CXXC5: unraveling its regulatory mechanisms in hematopoietic stem cell biology through proteomics and gene editing	6
Comprehensive assessment of the significance of cellular senescence-associated genes in neuroblastoma	6
Phylogenetic relationships between three Korean pit viper Gloydius (Serpentes: Crotalinae) species using mitochondrial DNA genes	5
Adhesion GPR123 is an indicator for recurrence and prognosis in bladder cancer	5
Epigenome editing: targeted manipulation of epigenetic modifications in plants	5
P14.5 functions to inhibit cell migration and can be used as a prognostic marker in hepatocellular carcinoma	5
Coffin-Siris syndrome in two chinese patients with novel pathogenic variants of ARID1A and SMARCA4	5
Establishment of a novel myocarditis mouse model based on cyclosporine A	5
Salivary amylase gene (AMY1) copy number variation has only a minor correlation with body composition in Chinese adults	5
Optimizing Bangkaew dog breed identification using DNA technology	5
Thymidine decreases the DNA damage and apoptosis caused by tumor‐treating fields in cancer cell lines	5
Transcriptome analysis reveals genes connected to temperature adaptation in juvenile antarctic krill Euphausia superba	5
Omi inhibition ameliorates neuron apoptosis and neurological deficit after subarachnoid hemorrhage in rats	5
Transcriptional upregulation of multiple earthworm chitinase genes following bacterial challenge suggests their implications in innate immunity	5
Genome-wide DNA methylation profiling in differentiating Crohn’s disease from intestinal tuberculosis	5
The coefficients of inbreeding revealed by ROH study among inbred individuals belonging to each type of the first cousin marriage: A preliminary report from North India	5
Current issues in forensic genetics	5
A novel pathogenic deletion in ISPD causes Walker-Warburg syndrome in a Chinese family	5
Estimating the age of single nucleotide polymorphic sites in humans	5
A novel approach of kinship determination based on the physical length of genetically shared regions of chromosomes	5
Transcriptional induction of TGF-β1 and endothelial-to-mesenchymal transition cell markers in human umbilical vein endothelial cells by Ebola virus infection	5
Prognostic significance of three endothelial nitric oxide synthase (eNOS) polymorphisms and metabolic syndrome (MetS) in patients with colorectal cancer	5
Centromere protein N promotes lung adenocarcinoma progression by activating PI3K/AKT signaling pathway	5
Full-length transcriptome combined with RNA sequence analysis of Fraxinus chinensis	5
Overexpression of TRIM44 mediates the NF-κB pathway to promote the progression of ovarian cancer	5
Epigenetic regulation of HERVs: Implications for cancer immunotherapy	4
A class I histone deacetylase HDA-2 is essential for embryonic development and size regulation of fertilized eggs in Caenorhabditis elegans	4
Transcriptomic profiling of the cold stress and recovery responsiveness of two contrasting Guizhou HE rice genotypes	4
Role of Brassica rapa SWEET genes in the defense response to Plasmodiophora brassicae	4
Genetic diversity and structure of Persicaria amphibia (Polygonaceae) in South Korea using genotyping by sequencing	4
Genome-wide association analysis for yield-related traits at the R6 stage in a Chinese soybean mini core collection	4
Uncovering microsatellite markers associated with agronomic traits of South Sudan landrace maize	4
Characterization and comparative analysis of the complete organelle genomes of three red macroalgae species (Neoporphyra dentata, Neoporphyra seriata, and Neopyropia yezoensis) and development of mole	4
Berberine protects against palmitate induced beta cell injury via promoting mitophagy	4
Disclosing the hidden nucleotide sequences: a journey into DNA barcoding of raptor species in public repositories	4
Pitfalls of whole exome sequencing in undefined clinical conditions with a suspected genetic etiology	4
A20 ameliorates disc degeneration by suppressing mTOR/BNIP3 axis-mediated mitophagy	4
A combination of upstream alleles involved in rice heading hastens natural long-day responses	4
Identification and characterization of Acinetobacter nosocomialis BfmRS, two-component regulatory system, essential for biofilm development	4
Molecular cloning, expression analysis, and functional characterization of Intelectin-1 from Chinese giant salamanders (Andrias davidianus)	4
Identification of Feronia-interacting proteins in Arabidopsis thaliana	4
Population genetics reveals new introgression in the nucleus herd of min pigs	4
Comparative analysis of VMT genes/proteins in selected plant species with emphasis on bread wheat (Triticum aestivum L.)	4
Using weighted gene co-expression network analysis (WGCNA) to identify the hub genes related to hypoxic adaptation in yak (Bos grunniens)	4
Complete mitochondrial genome of the Chinese Callipogon (Eoxenus) relictus (Cerambycidae: Prioninae) with phylogenetic analyses	4
Prognostic value of Nrf2/HO-1 expression and its correlation with occurrence in esophageal squamous cell carcinoma	4
Cryptic diversity and population genetic structure of the mantis shrimp Oratosquilla oratoria in South Korea	4
Genome-wide identification and expression profiling of the Wnt gene family in three abalone species	4
Complete chloroplast genomes of three Polygala species and indel marker development for identification of authentic polygalae radix (Polygala tenuifolia)	4
Genetic variation of seed oil characteristics in native Korean germplasm of Perilla crop (Perilla frutescens L.) using SSR markers	4
Mmu_circ_0000271 regulated the growth of ox-LDL-stimulated mouse vascular smooth muscle cells via sponging miR-5123	4
Helicobacter pylori infection induces gastric cancer cell malignancy by targeting HOXA-AS2/miR-509-3p/MMD2 axis	4
Deubiquitinating enzyme Josephin-2 stabilizes PHGDH to promote a cancer stem cell phenotype in hepatocellular carcinoma	4
A comparative investigation of single nucleotide variant calling for a personal non-Caucasian sequencing sample	4
Perillic acid disrupts the specification of germ layers by upregulating the FGF/MAPK pathway	4
Baicalin attenuates adriamycin-induced nephrotic syndrome by regulating fibrosis procession and inflammatory reaction	4
LncRNA-GAS5/miR-382-3p axis inhibits pulmonary artery remodeling and promotes autophagy in chronic thromboembolic pulmonary hypertension	4
Inactivation of epithelial sodium ion channel molecules serves as effective diagnostic biomarkers in clear cell renal cell carcinoma	4