Genes & Genomics

Article	Citations
Striate palmoplantar keratoderma: a novel DSG1 mutation, combined with an LDLR mutation	59
Correction to: A novel frameshift TBX4 variant in a family with ischio-coxo-podo-patellar syndrome and variable severity	23
Genomic survey of high-throughput RNA-Seq data implicates involvement of long intergenic non-coding RNAs (lincRNAs) in cytoplasmic male-sterility and fertility restoration in pigeon pea	20
Comprehensive assessment of the significance of cellular senescence-associated genes in neuroblastoma	20
miR-214-3p inhibits LPS-induced macrophage inflammation and attenuates the progression of dry eye syndrome by regulating ferroptosis in cells	19
Plant cross-fertilization for production of dual-specific antibodies targeting both Ebola virus–like particles and HER2 protein in F1 plants	17
Clinical report and genetic analysis of a novel variant in ZMIZ1 causing neurodevelopmental disorder with dysmorphic factors and distal skeletal anomalies in a Chinese family	16
CircRNA circ_0067772 aggravates the malignant progression of cutaneous squamous cell carcinoma by regulating miR-1238-3p/FOXG1 axis	16
Identification and validation of an ECM organization-related gene signature as a prognostic biomarker and therapeutic target for glioma patients	15
Whole exome sequencing revealed novel variants in consanguineous Pakistani families with intellectual disability	15
Comparative genomic analysis of Mycoplasma anatis strains	14
Characterization of the B cell receptor repertoire of patients with acute coronary syndrome	14
MALAT1 knockdown promoted cell viability and migration of LPS-treated MG-63 cells via sponging miR-212	13
METTL14 drives growth and metastasis of non-small cell lung cancer by regulating pri-miR-93-5p maturation and TXNIP expression	13
Gut Microbiome and colorectal cancer: discovery of bacterial changes with metagenomics application in Turkısh population	13
Mir-326 potentiates radiosensitivity of cervical squamous cell carcinoma through downregulating SMO expression in the Hedgehog signaling pathway	12
PIM3 regulates myocardial ischemia/reperfusion injury via ferroptosis	12
Analysis of protein determinants of host‐specific infection properties of polyomaviruses using machine learning	12
Comparative analysis of allele variation using allele frequencies according to sample size in Korean population	11
Alleles disrupting LBD37-like gene by an 136 bp insertion show different distributions between green and purple cabbages (Brassica oleracea var. capitata)	11
Transcriptome-wide characterization of the WRKY family genes in Lonicera macranthoides and the role of LmWRKY16 in plant senescence	11
Comparing of backfat microRNAomes of Landrace and Neijiang pig by high-throughput sequencing	11
Overlapping and non-overlapping roles of the class-I histone deacetylase-1 corepressors LET-418, SIN-3, and SPR-1 in Caenorhabditis elegans embryonic development	11
Harnessing epigenetic variability for crop improvement: current status and future prospects	10
Comparative analysis of human facial skin microbiome between topical sites compared to entire face	10

RPTOR methylation in the peripheral blood and breast cancer in the Chinese population	10
Preliminary study of genome-wide association identified novel susceptibility genes for thyroid-related hormones in Chinese population	10
YTHDF1 promotes the proliferation, migration, and invasion of prostate cancer cells by regulating TRIM44	10
Epigenetic reorganization during early embryonic lineage specification	10
Neferine increases sensitivities to multiple anticancer drugs via downregulation of Bcl-2 expression in renal cancer cells	9
HIST1H2BN induced cell proliferation and EMT phenotype in prostate cancer via NF-κB signal pathway	9
Genotype–environment interaction for milk production of Gyr cattle in Brazil and Colombia	9
Genetically predicted physical activity is associated with lower serum urate concentrations	9
PKC-β modulates Ca2+ mobilization through Stim1 phosphorylation	9
Comparative analysis of genome-based CAZyme cassette in Antarctic Microbacterium sp. PAMC28756 with 31 other Microbacterium species	9
missForest with feature selection using binary particle swarm optimization improves the imputation accuracy of continuous data	9
Genomic and transcriptomic analysis of Korean colorectal cancer patients	9
Identification of Saccharum CaM gene family and function characterization of ScCaM1 during cold and oxidant exposure in Pichia pastoris	9
In silico SARS-CoV-2 vaccine development for Omicron strain using reverse vaccinology	9
SmGDB: genome database of Salvia miltiorrhiza, an important TCM Plant	9
Autophagy induced by H. pylori VacA regulated the survival mechanism of the SGC7901 human gastric cancer cell line	9
Physiological and omics analysis of maize inbred lines during late grain development	8
Phosphofructokinase 1 platelet isoform induces PD-L1 expression to promote glioblastoma immune evasion	8
Genome-wide identification of GMP genes in Rosaceae and functional characterization of FaGMP4 in strawberry (Fragaria × ananassa)	8
MicroRNA 429 regulates MMPs expression by modulating TIMP2 expression in colon cancer cells and inflammatory colitis	8
A novel CLRN2 variant: expanding the mutation spectrum and its critical role in isolated hearing impairment	8
Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation	8
Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma	8
Genome-wide identification of drought-responsive microRNAs and their target genes in Chinese jujube by deep sequencing	8
Dual-specificity phosphatase 23 functions as a promising prognostic biomarker in non-small cell lung cancer	8
Transcriptome analysis reveals key defense-related genes upon SA induction in Cocos nucifera L.	8
Differential expression and functional analysis of circRNA in the ovaries of Yili geese at different egg-laying stages	8
Identification a novel de novo RUNX2 frameshift mutation associated with cleidocranial dysplasia	8
Expression profiles of TNF-Alpha and HERV-K Env proteins in multiple types of colon and lung disease	8
Association mapping analysis (AMA) for morpho-agronomic traits and leaf aromatic compounds using SSR markers in three types of Perilla crop collected from South Korea	8
Clinical and genetic analyses in syndromic intellectual disability with primary microcephaly reveal biallelic and de novo variants in patients with parental consanguinity	7
Identification of ulcerative colitis-specific immune cell signatures from public single-cell RNA-seq data	7
Effect of human endogenous retrovirus-K env gene knockout on proliferation of ovarian cancer cells	7
Histone methyltransferase KMT2D inhibits ENKTL carcinogenesis by epigenetically activating SGK1 and SOCS1	7
DNA methylome profiling of blood to identify individuals in a pair of monozygotic twins	7
Gut bacteria-derived 3-phenylpropionylglycine mitigates adipocyte differentiation of 3T3-L1 cells by inhibiting adiponectin-PPAR pathway	7
ceRNA network of lncRNA MIR210HG/miR-377-3p/LMX1A in malignant proliferation of glioma cells	7
Postoperative circulating tumor DNA detection and CBLB mutations are prognostic biomarkers for gastric cancer	7
LncRNA KTN1-AS1 facilitates esophageal squamous cell carcinoma progression via miR-885-5p/STRN3 axis	7
MiR-30c facilitates natural killer cell cytotoxicity to lung cancer through targeting GALNT7	7
CDK1 promotes the proliferation of melanocytes in Rex rabbits	7
Transcriptome analysis of flower colour reveals the correlation between SNP and differential expression genes in Phalaenopsis	7
FOXK1 regulates epithelial-mesenchymal transition and radiation sensitivity in nasopharyngeal carcinoma via the JAK/STAT3 signaling pathway	7
RelCurator: a text mining-based curation system for extracting gene–phenotype relationships specific to neurodegenerative disorders	7
Correction to: Comprehensive analysis the diagnosis, malignant progression and immune infiltrate of ANXA6 in prostate cancer	6
MED1 induces M2 polarization of tumor-associated macrophages to aggravate breast cancer	6
DJ-1 protects cell death from a mitochondrial oxidative stress due to GBA1 deficiency	6
A rare TNNT1 gene variant causing creatine kinase elevation in nemaline myopathy: c.271_273del (p.Lys91del)	6
DNA methylation of GDF-9 and GHR genes as epigenetic regulator of milk production in Egyptian Zaraibi goat	6
Repurposing existing drugs for monkeypox: applications of virtual screening methods	6

A novel role of the cotton calcium sensor CBL3 was involved in Verticillium wilt resistance in cotton	6
Transcriptome-based screening and validation of key genes for wool color in cashmere goats	6
Crocin alleviates neurotoxicity induced by bupivacaine in SH-SY5Y cells with inhibition of PI3K/AKT signaling	6
Bidirectional two-sample mendelian randomization analysis identifies causal associations between age at menarche and sarcopenia-related traits	6
Genomic analyses of intricate interaction of TE-lncRNA overlapping genes with miRNAs in human diseases	6
The effect of canagliflozin on gut microbiota and metabolites in type 2 diabetic mice	6
Genetic specificity study using next-generation sequencing (NGS) of peritoneal metastatic colorectal cancer compared to primary colorectal cancer	6
MiR-122, miR-133a, and miR-206 as potential biomarkers for post-mortem interval estimation	6
Construction of methylation driver gene-related prognostic signature and development of a new prognostic stratification strategy in neuroblastoma	6
MiR-1299 functions as a tumor suppressor to inhibit the proliferation and metastasis of gastric cancer by targeting ARF6	6
A novel study on CXXC5: unraveling its regulatory mechanisms in hematopoietic stem cell biology through proteomics and gene editing	6
Puerarin alleviates chronic renal failure-induced pyroptosis in renal tubular epithelial cells by targeting miR-342-3p/TGF-β/SMAD axis	6
Prognostic and immunological role of LASP2 in clear cell renal cell carcinoma	6
Transcriptome analysis of East Asian common octopus, Octopus sinensis, paralarvae	6
Correlation analysis of cancer stem cell marker CD133 and human endogenous retrovirus (HERV)-K env in SKOV3 ovarian cancer cells	6
Profiling of testis-specific or testis-predominant genes expressed in mouse male germ cell lines GC-1 and GC-2	6
Suppression of TBCK enhances TRAIL-mediated apoptosis by causing the inactivation of the akt signaling pathway in human renal carcinoma Caki-1 cells	6
Single-cell transcriptomic analysis reveals transcriptional and cell subpopulation differences between human and pig immune cells	6
Association between TGF-β/BMP signaling pathway polymorphisms and the risk of primary ovarian insufficiency in Korean women	6
Integrated analysis of single-cell RNA-seq and bulk RNA-seq revealed key genes for bone metastasis and chemoresistance in prostate cancer	6
IDO promotes the proliferation and invasion of prostate cancer cells through KYNU	6
A pan-cancer analysis unveiling the function of NR4A family genes in tumor immune microenvironment, prognosis, and drug response	5
Comparative whole genome analysis of face-derived Streptococcus infantis CX-4 unravels the functions related to skin barrier	5
A novel ATP2A2 mutation in Darier and genotype phenotype: correlation analysis	5
A novel approach of kinship determination based on the physical length of genetically shared regions of chromosomes	5
Long non-coding RNA TTC28-AS1 attenuates high glucose-induced damage in HK-2 cells depending on the regulation of miR-320a/CD2AP axis	5
High expression of HOXC6 predicts a poor prognosis and induces proliferation and inflammation in multiple myeloma cells	5
Long non-coding RNA NEAT1 promotes lipopolysaccharide-induced acute lung injury by regulating miR-424-5p/MAPK14 axis	5
Mesenchymal stem cell-derived exosome mir-342-3p inhibits metastasis and chemo-resistance of breast cancer through regulating ID4	5
Transcriptome analysis of tilapia streptococcus agalactiae in response to baicalin	5
Purposive breeding strategies drive genetic differentiation in Thai fighting cock breeds	5
Discovery and genome-wide characterization of a novel miniature inverted repeat transposable element reveal genome-specific distribution in Glycine	5
Characterization of the complete mitochondrial genome of a newly discovered torrent catfish, Liobagrus geumgangensis, and their phylogenetic relationships	5
Bacterial profile-based body fluid identification using a machine learning approach	5
LncRNA SNHG20 promotes cell proliferation and invasion by suppressing miR-217 in ovarian cancer	5
UBE2C regulating the lung carcinoma progression via inhibiting ubiquitin-proteasomal degradation to increase MMP9 protein stability	5
Suppression of synuclein gamma inhibits the movability of endometrial carcinoma cells by PI3K/AKT/ERK signaling pathway	5
Relative synonymous codon usage of ORF1ab in SARS-CoV-2 and SARS-CoV	5
LncRNA expression profile analysis of Mg2+-induced osteogenesis by RNA-seq and bioinformatics	5
Immune micro-environment analysis and drug screening for ovarian endometriosis	5
Genomic analysis of nuclear receptors and miRNAs identifies a role for the NR3C1/miR-200 axis in colon cancer	5
Transcriptome sequencing of the endangered land snail Karaftohelix adamsi from the Island Ulleung: De novo assembly, annotation, valuation of fitness genes and SSR markers	5
GVAF: generalized, flexible filtering software for annotated variant files	5
Human umbilical cord mesenchymal stem cells overexpressing RUNX1 promote tendon-bone healing by inhibiting osteolysis, enhancing osteogenesis and promoting angiogenesis	5
1, 25-(OH)2D3 protects against ER stress and miRNA dysregulation in Mus musculus neurons	5
Genetic analysis and population genetic structure of hard-shelled mussel, Mytilus coruscus Gould 1861 (Mytiloida: Mytilidae) from the coasts of South Korea based on mitochondrial cytochrome oxidase (C	5
Distinct granzyme k expression in immune cells: a single-cell rna-seq meta-analysis	5
Rare minisatellite alleles of MUC2-MS8 influence susceptibility to rectal carcinoma	5
ACT001 alleviates inflammation and pyroptosis through the PPAR-γ/NF-κB signaling pathway in LPS-induced alveolar macrophages	5
ICT1 deficiency leads to reduced oxygen resistance due to the cell wall damage in S. cerevisiae	4
Trait − driven analysis of the 2p15p16.1 microdeletion syndrome suggests a complex pattern of interactions between candidate genes	4
Transcriptomic analysis reveal the responses of dendritic cells to VDBP	4
Transcriptional induction of TGF-β1 and endothelial-to-mesenchymal transition cell markers in human umbilical vein endothelial cells by Ebola virus infection	4
Transethnic meta-analysis of exome-wide variants identifies new loci associated with male-specific metabolic syndrome	4
TissueSpace: a web tool for rank-based transcriptome representation and its applications in molecular medicine	4
Prognostic significance of three endothelial nitric oxide synthase (eNOS) polymorphisms and metabolic syndrome (MetS) in patients with colorectal cancer	4
Spreading-dependent or independent Sir2-mediated gene silencing in budding yeast	4
Subproteomic profiling from renal cortices in OLETF rats reveals mutations of multiple novel genes in diabetic nephropathy	4
Characteristics of circRNAs expression profiles in the piglets intestine induced by oxidative stress	4
Insignificant effects of loss of heterozygosity in HLA in the efficacy of immune checkpoint blockade treatment	4
MiR-200c-3p inhibits LPS-induced M1 polarization of BV2 cells by targeting RIP2	4
Comprehensive analysis of circular RNAs in nasopharyngeal cancer	4
Correlation between obstructive sleep apnea and cerebral small vessel disease: a mendelian randomization study	4
RETRACTED ARTICLE: Long non-coding RNA H19X promotes tumorigenesis and metastasis of colorectal cancer through regulating the miR-503-5p/KANK1 axis	4
Ckb and Ybx2 interact with Ribc2 and are necessary for the ciliary beating of multi-cilia	4
NEDD4L suppresses PD-L1 expression and enhances anti-tumor immune response in A549 cells	4
Methyltransferase-like 3 (METTL3) mediated N6-methyladenosine (m6A) modifications facilitate mir-25-3p maturation to promote gastrointestinal stromal tumors (GISTs) progression	4
Epigenome editing: targeted manipulation of epigenetic modifications in plants	4
Development of markers using microsatellite loci of two rove beetle species, Paederus fuscipes Curtis and Aleochara (Aleochara) curtula Goeze (Coleoptera: Staphylinidae), followed by analyses of genet	4
SIRT3-mediated mitochondrial unfolded protein response weakens breast cancer sensitivity to cisplatin	4
Epigenetic control of abiotic stress signaling in plants	4
Association of a novel antisense lncRNA TP73-AS1 polymorphisms and expression with colorectal cancer susceptibility and prognosis	4
Effects of TLR9/NF-κB on oxidative stress and inflammation in IPEC-J2 cells	4
Correction to: Mesenchymal stem cell-derived exosome mir-342-3p inhibits metastasis and chemo-resistance of breast cancer through regulating ID4	4
Proteome based analysis of circulating SARS-CoV-2 variants: approach to a universal vaccine candidate	4
Genome-wide identification of auxin-responsive microRNAs in the poplar stem	4
The effect of the PLIN1 gene on the metabolism and mitochondria of porcine skeletal muscle satellite cells	4
ANXA3, associated with YAP1 regulation, participates in the proliferation and chemoresistance of cervical cancer cells	4
Phylogeography of the Korean endemic Coreoleuciscus (Cypriniformes: Gobionidae): the genetic evidence of colonization through Eurasian continent to the Korean Peninsula during Late Plio-Pleistocene	4
P14.5 functions to inhibit cell migration and can be used as a prognostic marker in hepatocellular carcinoma	4

Gene expression profiling and in vitro functional studies reveal RAD54L as a potential therapeutic target in multiple myeloma	4
Biallelic mutations in pakistani families with autosomal recessive prelingual nonsyndromic hearing loss	4
The association study between CYP20A1, CYP4F2, CYP2D6 gene polymorphisms and coronary heart disease risk in the Han population in southern China	4
Application of RapidHIT™ ID for cell authentication by fast and convenient STR profiling	4
Phosphorylation of BIK1 is critical for interaction with downstream signaling components	4
Expression of lncRNA NEAT1 in endometriosis and its biological functions in ectopic endometrial cells as mediated via miR-124-3p	4
RBBP4 plays a vital role in the malignant progression of triple-negative breast cancer by regulating epithelial-mesenchymal transition	4
Causal relationship between smoking status, smoking frequency and bladder cancer: a Mendelian randomization study	4
Forensic genetic analysis of single-nucleotide polymorphisms and microhaplotypes in Koreans through next-generation sequencing using precision ID identity panel	4
Expression profiles and bioinformatic analysis of microRNAs in myocardium of diabetic cardiomyopathy mice	4
TAS2R38 bitter taste perception in the Koṅkaṇī Sārasvata Brahmin population	4