OOIR: Observatory of International Research

Papers

(The median citation count of Animal Cells and Systems is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
The impacts of resveratrol on the retinal degeneration in a rat model of retinitis pigmentosa induced by alkylation: an in-vivo study	35
Grub polypeptide extracts protect against oxidative stress through the NRF2-ARE signaling pathway	31
Beneficial effect of simvastatin on human umbilical vein endothelial cells gap junctions induced by TNF-α	27
Establishment of a stress granule reporter system for evaluating in vitro colon toxicity	20
Syncytin, envelope protein of human endogenous retrovirus (HERV): no longer ‘fossil’ in human genome	20
CKS1B promotes the progression of hepatocellular carcinoma by activating JAK/STAT3 signal pathway	18
Suppressive effects of (-)-tubaic acid on RANKL-induced osteoclast differentiation and bone resorption	16
Endothelial periostin regulates vascular remodeling by promoting endothelial dysfunction in pulmonary arterial hypertension	16
Comprehensive analysis of the prognostic value and immune implications of the TTK gene in lung adenocarcinoma: a meta-analysis and bioinformatics analysis	15
A genomic estimated breeding value-assisted reduction method of single nucleotide polymorphism sets: a novel approach for determining the cutoff thresholds in genome-wide association studies and best	14
Clerodendrum trichotomum extract improves metabolic derangements in high fructose diet-fed rats	14
Physicochemical and biological similarity assessment of LBAL, a biosimilar to adalimumab reference product (Humira®)	14
Bioactive peptides in the pancreatin-hydrolysates of whey protein support cell proliferation and scavenge reactive oxygen species	14
Combined inhibition of STAT and Notch signalling effectively suppresses tumourigenesis by inducing apoptosis and inhibiting proliferation, migration and invasion in glioblastoma cells	14
Factors affecting the cleavage efficiency of the CRISPR-Cas9 system	13
Hippo-YAP/TAZ pathway regulation: the crucial roles of lncRNAs in cancer	13
The anti-tumor effect of the IFNγ/Fas chimera expressed on CT26 tumor cells	13
Neuro-immune interactions at single-cell resolution in neurodevelopmental, infectious, and neurodegenerative diseases	12
Drug discovery inspired by bioactive small molecules from nature	12
MiR-29 and MiR-140 regulate TRAIL-induced drug tolerance in lung cancer	11
Identifying candidate genes associated with hippocampal dysfunction in a hemiparkinsonian rat model by transcriptomic profiling	11
Effects of prenatal bisphenol S and bisphenol F exposure on behavior of offspring mice	10
NUCB2/nesfatin-1 suppresses the acrosome reaction in sperm within the mouse epididymis	10
Characterization of differential gene expression of broiler chicken to thermal stress in discrete developmental stages	10
Unraveling ER dimerization dynamics in endocrine disruption based on a BRET-focused approach	10

Cynarin attenuates LPS-induced endothelial inflammation via upregulation of the negative regulator MKP-3	10
Genetic structure of Rhodeus sinensis reflects historical imprints of East Asian paleo-drainages	10
Nitrogen-doped carbon quantum dot regulates cell proliferation and differentiation by endoplasmic reticulum stress	10
TRAP1 functions in the morphogenesis of the embryonic kidney	9
Yap signalling regulates ductular reactions in mice with CRISPR/Cas9-induced glycogen storage disease type Ia	9
HSPA5 and FGFR1 genes in the mesenchymal subtype of glioblastoma can improve a treatment efficacy	9
Fine structural aspects on the web glue production in the golden orb-web spider Trichonephila clavata	9
Ginkgo biloba extract ameliorates skin fibrosis in a bleomycin-induced mouse model of systemic sclerosis	9
Neuroprotective effects of tannic acid in the postischemic brain via direct chelation of Zn²⁺	9
Modulated electro-hyperthermia therapy combined with Korean mistletoe extract treatment exerts a strong anti-tumor activity by enhancing cellular and humoral immune responses in mice	8
Transcriptome alterations in spermatogonial stem cells exposed to bisphenol A	8
Differences in the biological properties of mesenchymal stromal cells from traumatic temporomandibular joint fibrous and bony ankylosis: a comparative study	8
Germline expression of Imp-L2 in Drosophila females enhances reproductive activity and longevity	8
ECM1 is associated with endocrine resistance in ER⁺ breast cancers	8
A push–pull strategy for controlling Riptortus pedestris (Hemiptera: Alydidae) using host plant semiochemicals	8
Spexin-based galanin receptor 2 agonist improves renal injury in mice with type 2 diabetes	8
Puromycin-induced kidney injury and subsequent regeneration in adult zebrafish	8
Purple corn extract alleviates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like phenotypes in BALB/c mice	8
Scoparone attenuates PD-L1 expression in human breast cancer cells by MKP-3 upregulation	7
Luteolin reduces fear, anxiety, and depression in rats with post-traumatic stress disorder	7
Estradiol and progesterone regulate NUCB2/nesfatin-1 expression and function in GH3 pituitary cells and THESC endometrial cells	7
Role of Carbohydrate response element-binding protein in mediating dexamethasone-induced glucose transporter 5 expression in Caco-2BBE cells and during the developmental phase in mice	7
Polyhexamethylene guanidine phosphate, chloromethylisothiazolinone, and particulate matter are dispensable for stress granule formation in human airway epithelial cells	7
DNA Methylation and gene expression patterns are widely altered in fetal growth restriction and associated with FGR development	7
KRAB family is involved in network shifts in response to osmotic stress in camels	7
Prokinetic effects of diatrizoate meglumine (Gastrografin®) in a zebrafish for opioid-induced constipation model	6
Inhibition of ubiquitin specific peptidase 14 (USP14) promotes ER-phagy by inducing ER stress in human hepatoma HepG2 cells	6
Combination of dasatinib and quercetin promotes osteogenic differentiation and stemness maintenance of hPDLSCs via YAP/TAZ	6
Augmenting the human interactome for disease prediction through gene networks inferred from human cell atlas	6
NAA10 Hypomethylation is associated with particulate matter exposure and worse prognosis for patients with non-small cell lung cancer	5
LRRK2 decreases microglial actin dynamics by filamentous actin depolymerization and Rac1 inhibition	5
New insight of square stepping exercise in immune fine-tuning for anticipating emerging pandemics	5
Elucidating breed-specific variants of native pigs in Korea: insights into pig breeds’ genomic characteristics	5
Mirodenafil ameliorates skin fibrosis in bleomycin-induced mouse model of systemic sclerosis	5
Ank-mediated pyrophosphate regulates shear stress-induced small extracellular vesicle production in 3D-cultured osteocytes	5
Mannose-6-phosphate glycan for lysosomal targeting: various applications from enzyme replacement therapy to lysosome-targeting chimeras	5
Differential pathological changes in colon microenvironments in acute and chronic mouse models of inflammatory bowel disease	5
Long-read sequencing reveals novel transcript diversity in Polypterus senegalus	5
Detecting the differential genomic variants using cross-population phenotype-associated variant (XP-PAV) of the Landrace and Yorkshire pigs in Korea	5
Protective effect of fermented aloe extract on glutamate-induced cytotoxicity in HT22 cells	5
Synapto-protective effect of lithium on HIV-1 Tat-induced synapse loss in rat hippocampal cultures	4
RA-PR058, a novel ramalin derivative, reduces BACE1 expression and phosphorylation of tau in Alzheimer’s disease mouse models	4
Dopamine depletion alters neuroplasticity-related signaling in the rat hippocampus	4
Ongoing invasions by American bullfrogs and red-eared sliders in the Republic of Korea	4
Generation of mouse and rat xenogeneic ovaries in vitro for production of mouse oocyte	4
MTBP promoted the proliferation, migration and invasion of colon cancer cells by activating the expression of ZEB2	4
Cell-autonomous reduction of CYFIP2 is insufficient to induce Alzheimer's disease-like pathologies in the hippocampal CA1 pyramidal neurons of aged mice	4
Low-temperature pulverization-specific Sargassum horneri extract accelerates wound healing and attenuates inflammation in a mouse burn model	4
Licochalcone A attenuates NMDA-induced neurotoxicity	4
Time-sequential change in immune-related gene expression after irradiation in glioblastoma: next-generation sequencing analysis	4

Role of gut commensal bacteria in juvenile developmental growth of the host: insights from Drosophila studies	4
MKP-3 suppresses LPS-induced inflammatory responses in HUVECs via inhibition of p38 MAPK/NF-κB pathway	4
Crosstalk between endoplasmic reticulum stress response and autophagy in human diseases	4
Type II transmembrane serine proteases 4 (TMPRSS4) promotes proliferation, invasion and epithelial–mesenchymal transition in endometrial carcinoma cells (HEC1A and Ishikawa) via activation of MAPK and	4
Novel botulinum neurotoxin-A tibial nerve perineural injection to alleviate overactive bladder symptoms in male rats	4
The nasal lymphatic route of CSF outflow: implications for neurodegenerative disease diagnosis and monitoring	4
Effect of aerobic exercise and particulate matter exposure duration on the diversity of gut microbiota	4
Piperlongumine regulates genes involved in the skin barrier in epidermal keratinocyte HaCaT cells	4
Inositol Requiring Enzyme (IRE), a multiplayer in sensing endoplasmic reticulum stress	4
Emerging roles of polyunsaturated fatty acid synthesis pathway in colorectal cancer	3
Integrative transcriptomic profiling uncovers immune and functional responses to bisphenol a across multiple tissues in male mice	3
Early postnatal exposure to bicuculline modulates E/I balance and induces ASD-like behavioral phenotypes in mice	3
Effect of RNF113A deficiency on oxidative stress-induced NRF2 pathway	3
Dietary exposure of the water flea Daphnia galeata to microcystin-LR	3
Comparative transcriptome analysis between long- and short-term survival after pig-to-monkey cardiac xenotransplantation reveals differential heart failure development	3
Mitochondrial genome-based synthesis and timeline of Eurasian otter ( Lutra lutra ) phylogeography	3
AP001885.4 promotes the proliferation of esophageal squamous cell carcinoma cells by histone lactylation- and NF-κB (p65)-dependent transcription activation and METTL3-mediated mRNA stability of c-myc	3
GYY4137 protects against type 2 diabetes mellitus-associated myocardial autophagy by suppressing FOXO1 signal pathway	3
Gender-specific alteration of steroid metabolism and its impact on viral replication in a mouse model of hepatitis B virus infection	3
The role of microRNAs in the molecular link between circadian rhythm and autism spectrum disorder	3
Roles of prion proteins in mammalian development	3
Cell-autonomous reduction of CYFIP2 changes dendrite length, dendritic protrusion morphology, and inhibitory synapse density in the hippocampal CA1 pyramidal neurons of 17-month-old mice	3
Retinal transcriptome profiling identifies novel candidate genes associated with visual impairment in a mouse model of multiple sclerosis	3
Ginsenoside Rg3 attenuates pulmonary fibrosis by inhibiting endothelial to mesenchymal transition	3