OOIR: Observatory of International Research

Papers

(The median citation count of Animal Cells and Systems is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Grub polypeptide extracts protect against oxidative stress through the NRF2-ARE signaling pathway	47
Holoprosencephaly and cyclopia in bmp7b and bmpr1ba Crispant zebrafish	36
Establishment of a stress granule reporter system for evaluating in vitro colon toxicity	25
Beneficial effect of simvastatin on human umbilical vein endothelial cells gap junctions induced by TNF-α	24
LncRNA-mRNA integrated networks in the neuroendocrine system of bisphenol a-treated mice induce cellular dysfunctions by disrupting transcriptional homeostasis	20
The impacts of resveratrol on the retinal degeneration in a rat model of retinitis pigmentosa induced by alkylation: an in-vivo study	19
Syncytin, envelope protein of human endogenous retrovirus (HERV): no longer ‘fossil’ in human genome	19
Bioactive peptides in the pancreatin-hydrolysates of whey protein support cell proliferation and scavenge reactive oxygen species	18
Suppressive effects of (-)-tubaic acid on RANKL-induced osteoclast differentiation and bone resorption	18
Bavachin enhances paclitaxel sensitivity in ovarian cancer cells through modulation of mitochondrial function and ER stress	17
Comprehensive analysis of the prognostic value and immune implications of the TTK gene in lung adenocarcinoma: a meta-analysis and bioinformatics analysis	17
Endothelial periostin regulates vascular remodeling by promoting endothelial dysfunction in pulmonary arterial hypertension	17
Hippo-YAP/TAZ pathway regulation: the crucial roles of lncRNAs in cancer	16
A genomic estimated breeding value-assisted reduction method of single nucleotide polymorphism sets: a novel approach for determining the cutoff thresholds in genome-wide association studies and best	16
Comparative immunologic profiling of mRNA and protein-conjugated vaccines: acute inflammatory responses and anti-PEG antibody production	15
Clerodendrum trichotomum extract improves metabolic derangements in high fructose diet-fed rats	15
Down-regulation of HSPA9 reduces tyrosine hydroxylase-positive neurons in mouse substantia nigra and induces Parkinson’s disease-like motor impairments	14
The anti-tumor effect of the IFNγ/Fas chimera expressed on CT26 tumor cells	14
Factors affecting the cleavage efficiency of the CRISPR-Cas9 system	14
Drug discovery inspired by bioactive small molecules from nature	12
Effects of prenatal bisphenol S and bisphenol F exposure on behavior of offspring mice	12
Unraveling ER dimerization dynamics in endocrine disruption based on a BRET-focused approach	11
A comparative study of capacitation-mediated changes in whole mouse sperm proteome	11
MiR-29 and MiR-140 regulate TRAIL-induced drug tolerance in lung cancer	11
Neuro-immune interactions at single-cell resolution in neurodevelopmental, infectious, and neurodegenerative diseases	11

Identifying candidate genes associated with hippocampal dysfunction in a hemiparkinsonian rat model by transcriptomic profiling	11
NUCB2/nesfatin-1 suppresses the acrosome reaction in sperm within the mouse epididymis	10
Prdx6 regulates in vivo myeloid cell development via redox control during Xenopus embryogenesis	10
Cynarin attenuates LPS-induced endothelial inflammation via upregulation of the negative regulator MKP-3	10
Genetic structure of Rhodeus sinensis reflects historical imprints of East Asian paleo-drainages	10
The role of interleukin-17 in neurological disorders	9
HSPA5 and FGFR1 genes in the mesenchymal subtype of glioblastoma can improve a treatment efficacy	9
Characterization of differential gene expression of broiler chicken to thermal stress in discrete developmental stages	9
Neuroprotective effects of tannic acid in the postischemic brain via direct chelation of Zn²⁺	9
Fine structural aspects on the web glue production in the golden orb-web spider Trichonephila clavata	9
Nitrogen-doped carbon quantum dot regulates cell proliferation and differentiation by endoplasmic reticulum stress	9
Yap signalling regulates ductular reactions in mice with CRISPR/Cas9-induced glycogen storage disease type Ia	9
Transcriptome alterations in spermatogonial stem cells exposed to bisphenol A	8
TRAP1 functions in the morphogenesis of the embryonic kidney	8
Puromycin-induced kidney injury and subsequent regeneration in adult zebrafish	8
ECM1 is associated with endocrine resistance in ER⁺ breast cancers	8
Ginkgo biloba extract ameliorates skin fibrosis in a bleomycin-induced mouse model of systemic sclerosis	8
A push–pull strategy for controlling Riptortus pedestris (Hemiptera: Alydidae) using host plant semiochemicals	7
Role of Carbohydrate response element-binding protein in mediating dexamethasone-induced glucose transporter 5 expression in Caco-2BBE cells and during the developmental phase in mice	7
Modulated electro-hyperthermia therapy combined with Korean mistletoe extract treatment exerts a strong anti-tumor activity by enhancing cellular and humoral immune responses in mice	7
Scoparone attenuates PD-L1 expression in human breast cancer cells by MKP-3 upregulation	7
TRIM22 functions as a scaffold protein for autophagy initiation	7
Spexin-based galanin receptor 2 agonist improves renal injury in mice with type 2 diabetes	7
Estradiol and progesterone regulate NUCB2/nesfatin-1 expression and function in GH3 pituitary cells and THESC endometrial cells	7
KRAB family is involved in network shifts in response to osmotic stress in camels	7
Germline expression of Imp-L2 in Drosophila females enhances reproductive activity and longevity	7
Circ_0081343 promotes autophagy and alleviates pyroptosis via PI3 K/AKT/HIF-1α axis in hypoxia-induced fetal growth restriction of mice	6
Augmenting the human interactome for disease prediction through gene networks inferred from human cell atlas	6
Luteolin reduces fear, anxiety, and depression in rats with post-traumatic stress disorder	6
Mirodenafil ameliorates skin fibrosis in bleomycin-induced mouse model of systemic sclerosis	6
Combination of dasatinib and quercetin promotes osteogenic differentiation and stemness maintenance of hPDLSCs via YAP/TAZ	6
Differential pathological changes in colon microenvironments in acute and chronic mouse models of inflammatory bowel disease	6
Inhibition of ubiquitin specific peptidase 14 (USP14) promotes ER-phagy by inducing ER stress in human hepatoma HepG2 cells	6
Cytokeratin-1 is essential for the detection of laminar shear stress in endothelial cells	5
Comprehensive analysis of protective effects of Loranthus tanakae Franch. and Sav. on ovalbumin-induced atopic dermatitis in mice and TNF- α	5
Long-read sequencing reveals novel transcript diversity in Polypterus senegalus	5
Artesunate disrupts germ layer formation by inhibiting BMP signaling pathway	5
Ank-mediated pyrophosphate regulates shear stress-induced small extracellular vesicle production in 3D-cultured osteocytes	5
Elucidating breed-specific variants of native pigs in Korea: insights into pig breeds’ genomic characteristics	5
NAA10 Hypomethylation is associated with particulate matter exposure and worse prognosis for patients with non-small cell lung cancer	5
LRRK2 decreases microglial actin dynamics by filamentous actin depolymerization and Rac1 inhibition	5
New insight of square stepping exercise in immune fine-tuning for anticipating emerging pandemics	4
Novel botulinum neurotoxin-A tibial nerve perineural injection to alleviate overactive bladder symptoms in male rats	4
Detecting the differential genomic variants using cross-population phenotype-associated variant (XP-PAV) of the Landrace and Yorkshire pigs in Korea	4
Effect of aerobic exercise and particulate matter exposure duration on the diversity of gut microbiota	4
Dopamine depletion alters neuroplasticity-related signaling in the rat hippocampus	4
Mannose-6-phosphate glycan for lysosomal targeting: various applications from enzyme replacement therapy to lysosome-targeting chimeras	4
Licochalcone A attenuates NMDA-induced neurotoxicity	4
The nasal lymphatic route of CSF outflow: implications for neurodegenerative disease diagnosis and monitoring	4
Ongoing invasions by American bullfrogs and red-eared sliders in the Republic of Korea	4

Protective effect of fermented aloe extract on glutamate-induced cytotoxicity in HT22 cells	4
Troponin I – a comprehensive review of its function, structure, evolution, and role in muscle diseases	4
Piperlongumine regulates genes involved in the skin barrier in epidermal keratinocyte HaCaT cells	4
Generation of mouse and rat xenogeneic ovaries in vitro for production of mouse oocyte	4
Inositol Requiring Enzyme (IRE), a multiplayer in sensing endoplasmic reticulum stress	3
Role of gut commensal bacteria in juvenile developmental growth of the host: insights from Drosophila studies	3
Gender-specific alteration of steroid metabolism and its impact on viral replication in a mouse model of hepatitis B virus infection	3
RNA binding protein HuD regulates fatty acid oxidation in pancreatic β-cells by modulating long-chain acyl-CoA dehydrogenase expression	3
Effect of RNF113A deficiency on oxidative stress-induced NRF2 pathway	3
Dietary exposure of the water flea Daphnia galeata to microcystin-LR	3
Crosstalk between endoplasmic reticulum stress response and autophagy in human diseases	3
RA-PR058, a novel ramalin derivative, reduces BACE1 expression and phosphorylation of tau in Alzheimer’s disease mouse models	3
Early postnatal exposure to bicuculline modulates E/I balance and induces ASD-like behavioral phenotypes in mice	3
Ginsenoside Rg3 attenuates pulmonary fibrosis by inhibiting endothelial to mesenchymal transition	3
The role of microRNAs in the molecular link between circadian rhythm and autism spectrum disorder	3
Cell-autonomous reduction of CYFIP2 changes dendrite length, dendritic protrusion morphology, and inhibitory synapse density in the hippocampal CA1 pyramidal neurons of 17-month-old mice	3
Cell-autonomous reduction of CYFIP2 is insufficient to induce Alzheimer's disease-like pathologies in the hippocampal CA1 pyramidal neurons of aged mice	3
Low-temperature pulverization-specific Sargassum horneri extract accelerates wound healing and attenuates inflammation in a mouse burn model	3
Synapto-protective effect of lithium on HIV-1 Tat-induced synapse loss in rat hippocampal cultures	3
GYY4137 protects against type 2 diabetes mellitus-associated myocardial autophagy by suppressing FOXO1 signal pathway	3
Differential effects of nesfatin-1 on proliferation and migration in normal and cancerous human lung cells via the PI3K/AKT pathway	3