OOIR: Observatory of International Research

Papers

(The TQCC of Toxicological Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Re-evaluation of a microbiological acceptable daily intake for tylosin based on its impact on human intestinal microflora	24
In utero exposure to electronic-cigarette aerosols decreases lung fibrillar collagen content, increases Newtonian resistance and induces sex-specific molecular signatures in neonatal mice	20
Policosanol suppresses tumor progression in a gastric cancer xenograft model	19
Atg5 knockout induces alternative autophagy via the downregulation of Akt expression	19
Effect of CTMP1 gene on pulmonary fibrosis	15
Kaempferol induces apoptosis through the MAPK pathway and regulates JNK-mediated autophagy in MC-3 cells	13
Sub-lethal effects of organophosphates and synthetic pyrethroid insecticides on muscle tissue transaminases of Oreochromis niloticus in vivo	13
Evaluation of acute, 28-day, 13-week repeated dose oral toxicity and genotoxicity of a herbal extract (HemoHIM G) from Angelica sinensis, Ligusticum chuanxiong, and Peaonia lactiflora	12
Current hPSC-derived liver organoids for toxicity testing: Cytochrome P450 enzymes and drug metabolism	11
Efficiency of pharmaceutical toxicity prediction in computational toxicology	11
Radioactive Iodine-induced hypothyroidism interferes with the maturation of reproductive organs during puberty in immature female rats	10
Imatinib mesylate promotes melanogenesis through the modulation of p38 and MITF in murine cells	9
Acetate attenuates lead-induced dysregulation of testicular steroidogenesis and spermatogenesis by targeting oxidative stress, inflammatory cytokines, and apoptosis	9
Pre-validation study of spectrophotometric direct peptide reactivity assay (Spectro-DPRA) as a modified in chemico skin sensitization test method	9
Increase in the sensitivity to PLX4720 through inhibition of transcription factor EB-dependent autophagy in BRAF inhibitor-resistant cells	9
Metabolic effects of diclofenac on the aquatic food chain – 1 H-NMR study of water flea-zebrafish system	9
Unveiling the link between arsenic toxicity and diabetes: an in silico exploration into the role of transcription factors	9
In vitro toxicological assessment of PhSeZnCl in human liver cells	8
Establishment of a platform for measuring mitochondrial oxygen consumption rate for cardiac mitochondrial toxicity	8
A convenient spectrophotometric test for screening skin-sensitizing chemicals using reactivity with glutathione in chemico	8
Ameliorative or corrective effects of Fig “Ficus carica” extract on nickel-induced hepatotoxicity in Wistar rats	8
Comparative study on estrogen receptor alpha dimerization and transcriptional activity of parabens	8
Assessment of agonistic and antagonistic properties of humidifier disinfectants to the estrogenic and androgenic receptors by transactivation assay	8
Short-term health effects of tear agents chlorobenzylidenemalononitrile and oleoresin capsicum during the civil riots of Santiago de Chile in 2019–2020	7
Baicalein inhibits IL-1β-induced extracellular matrix degradation with decreased MCP-1 expression in primary rat chondrocytes	7

Acute toxicity assessment of nine organic UV filters using a set of biotests	7
Pelargonium sidoides extract mediates nephrotoxicity through mitochondrial malfunction and cytoskeleton destabilization	7
Therapeutic strategies for colorectal cancer: antitumor efficacy of dopamine D2 receptor antagonists	7
CKD-516 potentiates the anti-cancer activity of docetaxel against epidermal growth factor receptor tyrosine kinase inhibitor-resistant lung cancer	7
Algorithm for environmental risk assessment of cosmetics to reduce their environmental impact	6
Silencing circPalm2 inhibits sepsis-induced acute lung injury by sponging miR-376b-3p and targeting MAP3K1	6
Upregulation of YPEL3 expression and induction of human breast cancer cell death by microRNAs	6
Updates on the mechanisms of toxicities associated with monoclonal antibodies targeting growth factor signaling and immune cells in cancer	6
Semi-automated approach for generation of biological networks on drug-induced cholestasis, steatosis, hepatitis, and cirrhosis	6
Quantification and visualization of metastatic lung tumors in mice	6
Exploring the various functions of PHD finger protein 20: beyond the unknown	6
Toxicologic pathological mechanism of acute lung injury induced by oral administration of benzalkonium chloride in mice	5
Publisher Correction: Short-term inhalation exposure to cigarette smoke induces oxidative stress and inflammation in lungs without systemic oxidative stress in mice	5
Integrative roles of sphingosine kinase in liver pathophysiology	5
In vitro study of silver nanoparticles-induced embryotoxicity using a rat whole embryo culture model	5
Exposure to China dust exacerbates testicular toxicity induced by cyclophosphamide in mice	5
Lipid hydroperoxide-derived insulin resistance and its inhibition by pyridoxamine in skeletal muscle cells	5
Publication trends in South Korean research on particulate matter and health effects during two decades (2000–2019)	5
Lysine-63-linked polyubiquitination: a principal target of cadmium carcinogenesis	5
Protective effect of cilostazol on vascular injury in rats with acute ischemic stroke complicated with chronic renal failure	5
Comparison of structural characteristics and molecular markers of rabbit skin, pig skin, and reconstructed human epidermis for an ex vivo human skin model	4
HEBP2 affects sensitivity to cisplatin and BCNU but not to paclitaxel in MDA-MB-231 breast cancer cells	4
Induction of synergistic apoptosis by tetramethoxystilbene and nutlin-3a in human cervical cancer cells	4
Anti-senescence and anti-apoptotic effects of immature Citrus unshiu peel ethanol extract on ultraviolet B-irradiated skin keratinocytes	4
Endotoxin of Porphyromonas gingivalis amplifies the inflammatory response in hyperglycemia-induced zebrafish through a mechanism involving chitinase-like protein YKL-40 analogs	4
Biosafety assessments of hexafluoropropylene trimer derivative as a fluorinated cooling fluid for electronics	4
Retraction Note: Flavonoid fractions of diosmin and hesperidin mitigate lead acetate-induced biochemical, oxidative stress, and histopathological alterations in Wistar rats	4
Pathological changes in various organs in HLA-B*57:01 transgenic mice with abacavir-induced skin eruption	4
Anthraquinone as emerging contaminant: technological, toxicological, regulatory and analytical aspects	4
The preventive effect of Mori Ramulus on oxidative stress-induced cellular damage in skeletal L6 myoblasts through Nrf2-mediated activation of HO-1	4
Roundup® induces premature senescence of mouse granulosa cells via mitochondrial ROS-triggered NLRP3 inflammasome activation	4
Steroidogenic cytochrome P450 enzymes as drug target	4
Enhancement of renal fibrosis in PHF20 transgenic mice	4
Scavenger receptor class F member 2 (SCARF2) as a novel therapeutic target in glioblastoma	4
Acute toxicity of aqueous extract of Ambrosia arborescens Mill. on biochemical and histopathological parameters in rats	4
Correction to: No prominent toxicity of polyethylene microplastics observed in neonatal mice following intratracheal instillation to dams during gestational and neonatal period	4
Mitochondrial dynamics when mitochondrial toxic chemicals exposed in 3D cultured mouse embryonic stem cell	4
Integrated transcriptomic analysis of liver and kidney after 28 days of thioacetamide treatment in rats	4
Sargassum horneri extract attenuates high-dose acetaminophen-induced hepatotoxicity by enhancing the antioxidant activity and inhibiting acetaminophen activation in the mouse liver	4