Toxicological Research

(The median citation count of Toxicological Research is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
A history of the roles of cytochrome P450 enzymes in the toxicity of drugs67
Flavonoids: structure–function and mechanisms of action and opportunities for drug development48
No prominent toxicity of polyethylene microplastics observed in neonatal mice following intratracheal instillation to dams during gestational and neonatal period20
Assessment of acute and repeated pulmonary toxicities of oligo(2-(2-ethoxy)ethoxyethyl guanidium chloride in mice20
Celecoxib induces apoptosis through Akt inhibition in 5-fluorouracil-resistant gastric cancer cells17
Heavy metals in hair and nails as markers of occupational hazard among welders working in United Arab Emirates13
Differential mechanisms underlying methotrexate-induced cell death and epithelial-mesenchymal transition in A549 cells13
Hepatoprotective effect of Centella asiatica 50% ethanol extract against acetaminophen-induced acute liver injury in BALB/c mice13
Distribution of organochlorine pesticide pollution in water, sediment, mollusk, and fish at Saguling Dam, West Java, Indonesia13
Elevated anxiety, hypoactivity, memory deficits, decreases of brain serotonin and 5-HT-1A receptors expression in rats treated with omeprazole13
Multifunctional biological properties and phytochemical constituents of Mangifera indica L. seed kernel extract for preventing skin aging12
The in vitro toxicity evaluation of halloysite nanotubes (HNTs) in human lung cells12
Grading criteria of histopathological evaluation in BCOP assay by various staining methods11
Acute toxicity and morphology alterations of glyphosate-based herbicides to Daphnia magna and Cyclops vicinus11
A curcumin analog CA-5f inhibits urokinase-type plasminogen activator and invasive phenotype of triple-negative breast cancer cells11
Evaluation of the skin sensitization potential of metal oxide nanoparticles using the ARE-Nrf2 Luciferase KeratinoSensTM assay10
Effect of low-dose corticosterone pretreatment on the production of inflammatory mediators in super-low-dose LPS-primed immune cells10
Testosterone recuperates deteriorated male fertility in cypermethrin intoxicated rats10
Analysis of organochlorine pesticides residues in fish from Edko Lake (North of Egypt) using eco-friendly method and their health implications for humans9
Trans-chalcone suppresses tumor growth mediated at least in part by the induction of heme oxygenase-1 in breast cancer9
Monosodium glutamate induces memory and hepatic dysfunctions in mice: ameliorative role of Jobelyn® through the augmentation of cellular antioxidant defense machineries9
β-caryophyllene improves sexual performance via modulation of crucial enzymes relevant to erectile dysfunction in rats8
Regulation of cardiovascular biology by microsomal epoxide hydrolase8
In utero exposure to electronic-cigarette aerosols decreases lung fibrillar collagen content, increases Newtonian resistance and induces sex-specific molecular signatures in neonatal mice8
Urinary 1-aminopyrene level in Koreans as a biomarker for the amount of exposure to atmospheric 1-nitropyrene8
Protective effect of fisetin against subchronic chlorpyrifos-induced toxicity on oxidative stress biomarkers and neurobehavioral parameters in adult male albino mice7
Developmental, behavioral and endocrine alterations in male rats at early and late postnatal life following in utero exposure to low dose di-n-butylphthalate7
The preventive effect of Mori Ramulus on oxidative stress-induced cellular damage in skeletal L6 myoblasts through Nrf2-mediated activation of HO-17
Chemokine expression in human 3-dimensional cultured epidermis exposed to PM2.5 collected by cyclonic separation6
Hepatic and renal damage by alcohol and cigarette smoking in rats6
Advantages of omics technology for evaluating cadmium toxicity in zebrafish6
Fimbristylis ovata and Artemisia vulgaris extracts inhibited AGE-mediated RAGE expression, ROS generation, and inflammation in THP-1 cells6
Evaluation of genetic toxicity, acute and sub-chronic oral toxicity and systemic safety of Agrimonia pilosa and Rhus gall 50% ethanolic extract mixture (APRG64) in vitro and in vivo (rodent and non-ro6
Flavonoid fractions of diosmin and hesperidin mitigate lead acetate-induced biochemical, oxidative stress, and histopathological alterations in Wistar rats6
Trade‐offs between male fertility reduction and selected growth factors or the klotho response in a lipopolysaccharide-dependent mouse model6
Oral methylmercury intoxication aggravates cardiovascular risk factors and accelerates atherosclerosis lesion development in ApoE knockout and C57BL/6 mice5
Policosanol suppresses tumor progression in a gastric cancer xenograft model5
The effect of streptozotocin induced diabetes on sperm function: a closer look at AGEs, RAGEs, MAPKs and activation of the apoptotic pathway5
Beneficial effects of Diplectria barbata (Wall. Ex C. B. Clarke) Franken et Roos extract on aging and antioxidants in vitro and in vivo5
Effects of subacute oral administration of aqueous extract of Macaranga barteri Müll.Arg (Euphorbiaceae) leaf on anthropometric and haematological parameters in rats5
Exposure to China dust exacerbates testicular toxicity induced by cyclophosphamide in mice5
The role of noble bumblebee (Bombus terrestris) queen glycosaminoglycan in aged rat and gene expression profile based on DNA microarray4
Acute toxicity and antimalarial studies of extract of  Allophylus spicatus in animals4
Evaluation of the acute, sub-chronic and chronic oral toxicity, genetic toxicity, and safety of a Lomens-P04
Standardization of the first Korean national reference standard for snake (Gloydius brevicaudus) antivenom4
Teratogenic effects of ethanol extract of Curcuma mangga Val. rhizomes in wistar rats4
Neurotoxicity of anthracene and benz[a]anthracene involves oxidative stress-induced neuronal damage, cholinergic dysfunction and disruption of monoaminergic and purinergic enzymes4
Non-toxic nature of chebulinic acid on biochemical, hematological and histopathological analysis in normal Sprague Dawley rats4
A review on the pharmacokinetic properties and toxicity considerations for chloroquine and hydroxychloroquine to potentially treat coronavirus patients4
Recent insights into autophagy and metals/nanoparticles exposure4
Beet root (Beta vulgaris) protects lipopolysaccharide and alcohol-induced liver damage in rat4
AXL is required for hypoxia-mediated hypoxia-inducible factor-1 alpha function in glioblastoma4
Scavenger receptor class F member 2 (SCARF2) as a novel therapeutic target in glioblastoma4
Sub-acute toxicity study on hydromethanolic leaves extract of Combretum hypopilinum (Combretaceae) Diels in Wistar rats4
Estrogen exposure causes the progressive growth of SK-Hep1-derived tumor in ovariectomized mice4
Anti-inflammatory effects of Athyrium yokoscense extract via inhibition of the Erk1/2 and NF-κB pathways in bisphenol A-stimulated A549 cells4
Effects of toxicants on endoplasmic reticulum stress and hepatic cell fate determination4
Semi-automated approach for generation of biological networks on drug-induced cholestasis, steatosis, hepatitis, and cirrhosis3
Fimbristylis ovata extract and its ability to encounter AGEs-induced neurotoxicity in SH-SY5Y3
Hemorrhagic changes and microglia activation induced by Macrovipera lebetina obtusa venom with the inhibited enzymatic activity in rat brain3
Evaluation of the in vitro and in vivo genotoxicity of a Dioscorea Rhizome water extract3
Protective efficacy of Coriandrum sativum seeds against arsenic induced toxicity in Swiss albino mice3
Ameliorative effects of Dictyota dichotoma on hepatotoxicity induced by gibberellic acid in albino rats3
In vitro toxicological assessment of PhSeZnCl in human liver cells3
The effects of co-exposure to methyl paraben and dibutyl phthalate on cell line derived from human skin3
Increase in the sensitivity to PLX4720 through inhibition of transcription factor EB-dependent autophagy in BRAF inhibitor-resistant cells3
Comparison of structural characteristics and molecular markers of rabbit skin, pig skin, and reconstructed human epidermis for an ex vivo human skin model3
Protective effects of cardamom aqueous extract against tamoxifen-induced pancreatic injury in female rats3
Explanation of difenoconazole removal by chitosan with Langmuir adsorption isotherm and kinetic modeling3
Flow cytometric evaluation of the potential of metal oxide nanoparticles for skin sensitization using 5-Bromo-2-deoxyuridine3
Characterisation of changes in global genes expression in the lung of ICR mice in response to the inflammation and fibrosis induced by polystyrene nanoplastics inhalation3
Antiphotoaging properties of Zingiber montanum essential oil isolated by solvent-free microwave extraction against ultraviolet B-irradiated human dermal fibroblasts3
Increased expression of TCF3, transcription factor 3, is a defense response against methylmercury toxicity in mouse neuronal C17.2 cells3
Single- and repeated-dose 28-day oral toxicity study of MDM hydantoin in Sprague–Dawley rats3
Assessment of agonistic and antagonistic properties of humidifier disinfectants to the estrogenic and androgenic receptors by transactivation assay2
Blood vessel remodeling in the cerebral cortex induced by binge alcohol intake in mice2
Sub-lethal effects of organophosphates and synthetic pyrethroid insecticides on muscle tissue transaminases of Oreochromis niloticus in vivo2
Machine-learning based prediction models for assessing skin irritation and corrosion potential of liquid chemicals using physicochemical properties by XGBoost2
Integrative roles of sphingosine kinase in liver pathophysiology2
Impacts of PAH accumulation on reproductive hormones, indices of oxidative stress and BPDE-albumin adduct in women with recurrent pregnancy loss2
Protective role of selenium on structural change of human hemoglobin in the presence of vinyl chloride2
Ameliorative or corrective effects of Fig “Ficus carica” extract on nickel-induced hepatotoxicity in Wistar rats2
Neuroprotective efficacy of N-t-butylhydroxylamine (NtBHA) in transient focal ischemia in rats2
Assessment of toxicity and genotoxic safety profile of novel fisetin ruthenium-p-cymene complex in mice2
The Wnt/β-catenin signaling pathway plays a role in drug-induced liver injury by regulating cytochrome P450 2E1 expression2
Acute toxicity of aqueous extract of Ambrosia arborescens Mill. on biochemical and histopathological parameters in rats2
Characterization of complement C3 as a marker of alpha-amanitin toxicity by comparative secretome profiling2
Pre-validation study of spectrophotometric direct peptide reactivity assay (Spectro-DPRA) as a modified in chemico skin sensitization test method2
Rapid and simultaneous purification of aflatoxin B1, zearalenone and deoxynivalenol using their monoclonal antibodies and magnetic nanoparticles2
Phosphodiesterase 11 A (PDE11A), a potential biomarker for glioblastoma2
Toxicologic pathological mechanism of acute lung injury induced by oral administration of benzalkonium chloride in mice2
Evaluation of the skin phototoxicity of systemically administered pharmaceuticals in Sprague–Dawley rats2
Toxicological and safety evaluations of Weissella cibaria strain CMU in animal toxicity and genotoxicity2