OOIR: Observatory of International Research

Papers

(The median citation count of Biochip Journal is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
A Laser-Micromachined PCB Electrolytic Micropump Using an Oil-Based Electrolyte Separation Barrier	94
Microfabricated Stretching Devices for Studying the Effects of Tensile Stress on Cells and Tissues	87
A Review of Microfluidic Chip-Based Strategies for Extracellular Vesicle Isolation: Bridging Traditional Methods and Clinical Translation	59
Recent Advances of Concentration Gradient Microfluidic Chips for Drug Screening	53
Ligand-Driven Enzyme-Accelerated Signal Enhancement via Polydopamine Deposition for Visualizing Cell Receptors	48
Enhancement of Overlimiting Current in a Three-Dimensional Hierarchical Micro/Nanofluidic System by Non-uniform Compartmentalization	46
Numerical-Simulation-Based Buffer Design for Microchip Electrophoresis with Capacitively Coupled Contactless Conductivity Detection	42
Advancing Pharmacokinetics Research with Organ-on-Chips: A Microphysiological Approach to ADME Studies	40
Recent Advances in Electrochemical and Optical Biosensors for Cancer Biomarker Detection	39
Advancing Blood–Brain Barrier-on-a-Chip Models Through Numerical Simulations	37
Surface engineering of polymer microneedle arrays for enhanced sensitivity	33
Microfluidic Platform for On-site Simultaneous Analysis of Ketamine and MDMA in Urine	29
In Vitro Assays of Neurite Outgrowth and Synapse Formation Using Thermoplasmonic Ablation Technique	28
Tandem Invasive Signal Amplification for Sensitive, Fluorescence Polarization-Based Terminal Transferase Activity Assay	26
Recent Advances in Aptasensor Technologies for the Detection of Lung Diseases: A Comprehensive Review	26
Modelling Cardiovascular Diseases Using Human Microphysiological Systems	25
Deep Learning-Assisted Droplet Digital PCR for Quantitative Detection of Human Coronavirus	24
Polymerase Elongation onto Patterned DNA for Random Accessed DNA Data Storage	24
Helicobacter pylori-Vacuolating Cytotoxin A Induces Neurotoxic Neuroinflammation in Human Multicellular Models	23
Thermoplasmonic Scaffold Design for the Modulation of Neural Activity in Three-Dimensional Neuronal Cultures	23
Engineered Blood Clots for Embolization in a 3D Microfluidic Chip Model Mimicking Vascular Structures	23
Development of a 3D Vascularized Skeletal Muscle Model Using Bi-Layered Seeding Methods	23
Label-free Electrochemical Biosensor for Glycated Hemoglobin (HbA1c) and Glycated Albumin (GA) Measurement Using 4-mercapto-phenyl Boronic Acid Embedded Affinity	22
Nitrogen-Containing Bisphosphonate Carbon Dots with High Affinity to Calcium-Based Biomaterials for Suppression of Osteoclasts	22
DNA-Wrapped CNT Sensor for Small Nucleic Acid Detection: Influence of Short Complementary Sequence	22

Electrokinetic Paper-Based Ion Pre-concentrator for On-Site Detection of Ionic Water Contaminants	22
Plasmonic-Multichromatic Sensor for Gallic Acid Assay Utilizing Ag-Coated Au Nanobipyramids	21
Integrating the Blood–Brain Barrier and Blood-CSF Barrier Organ-on-Chip Models: Development and Future Directions	21
Organ-On-A-Chip Technology: An In-depth Review of Recent Advancements and Future of Whole Body-on-chip	21
Current Advances in Paper-Based Biosensor Technologies for Rapid COVID-19 Diagnosis	20
One-Step Immunoassay of Influenza Virus Using Screened Fv-Antibodies and Switching Peptides	20
Non-Invasive, Non-Enzymatic Glucose Sensor Using Phenylboronic Acid with Reversible Glucose Interaction	20
Sensitive Detection of SARS-CoV-2 Spike Protein Using an Aptamer Sandwich Assay-Based Electrochemical Biosensor	19
Erratum: Brain Endothelial Cells Regulate Neural Stem Cell Maintenance by Consuming Growth Factors in a Reconstituted Vascular Neural Stem Cell Niche	19
Organ-on-a-Chip Models for Studying Gut–Brain Axis and Appetite Regulation	18
Enhancement of Maturation and Functionality of Human Fabry Disease Kidney Organoids in a Microfluidic Gradient Chip	18
A Lateral Flow Assay for Nucleic Acid Detection Based on Rolling Circle Amplification Using Capture Ligand-Modified Oligonucleotides	18
Polydopamine Nanoparticle-Incorporated Fluorescent Hydrogel for Fluorescence Imaging-Guided Photothermal Therapy of Cancers	18
Non-invasive Thermohydrodynamic Approach for Fast Cell Manipulation at the Microscale	17
Modeling Preeclampsia: From 2D Cultures to Placenta-on-a-Chip Technologies	17
Classification of DNA Mixtures by Nanoelectrokinetic Driftless Preconcentration	17
Establishment and Evaluation of Immunocolloidal Gold Chromatography Method in the Sandwich Mode for Novel Coronavirus Double-Antibody Detection	17
Real-Time Detection of SARS-CoV-2 Nucleocapsid Antigen Using Data Analysis Software and IoT-Based Portable Reader with Single-Walled Carbon Nanotube Field Effect Transistor	17
Recent Strategies in Nanomaterials-Based Signal Amplification of Electrochemical Biosensors	16
Recording Fast Ion Channel Kinetics Using Non-invasive Electrical Impedance Spectroscopy	16
Acoustofluidic Microbioreactor Using Surface Acoustic Wave-induced Acoustic Streaming Flow	16
Microphysiological Systems as Organ-Specific In Vitro Vascular Models for Disease Modeling	16
Towards Nanomaterial-Incorporated Soft Actuators: from Inorganic/Organic Material-Based Soft Robot to Biomaterial-Based Biohybrid Robot	15
Recent Advances in Electrochemical and Optical Point-of-Care Testing for Marine Biotoxin Detection	15
One-Step Immunoassay for the Detection of SARS-CoV-2 Nucleocapsid Protein Using Screened Fv-Antibodies	15
Recent Advances in 3D-Cultured Brain Tissue Models Derived from Human iPSCs	15
Surface Modification Strategies for Biomedical Applications: Enhancing Cell–Biomaterial Interfaces and Biochip Performances	14
SARS-CoV-2 S1-Inducing Reactive Astrocyte and Proteinopathies via TANK-Binding Kinase 1 in Human Neuroglia Model	14
Low-Powered pH-Stable Nano-electrokinetically Enhanced Lateral Flow Assay for COVID-19 Antigen Test	13
Recent Progress in Rapid Biosensor Fabrication Methods: Focus on Electrical Potential Application	13
Spheroid-Matrix Kidney-on-a-Chip Model for Predicting Drug-Induced Nephrotoxicity	13
Miniaturized and Automated Optical-Switch Raman Spectroscopy Enabling Multiwell Surface-Enhanced Raman Spectroscopy Screening More than 26,000 Wells per Day	13
A Label-Free, One-Step Isothermal Assay for Sensitive Detection of Telomerase Activity Using Light-Up Aptamer	13
Critical Challenges and Future Direction in Extracellular Vesicle Research and Commercialization	13
Synergetic Chemo-Mechano Antimicrobial Puncturable Nanostructures for Efficient Bioaerosol Removal	13
Matrix–Matrix Interfaces Orchestrate Early Mechanosensitive Transition from Attractor To Track	13
Continuous Isolation of Stem-Cell-Derived Extracellular Vesicles (SC-EVs) by Recycled Magnetic Beads in Microfluidic Channels	12
A Gut–Liver–Kidney (GLK) Multi-Organ Chip for Physiologically Modeling the Renal Filtration and Reabsorption of Oral Drugs	12
Functionalized Carbon Quantum Dots Derived from Zelkova serrata Plant Leaves for the Detection of Normetanephrine in Geriatric Plasma Samples and ROS-Induced Antibacterial Applications Using a Plausib	12
Fabrication of Nephrotoxic Model by Kidney-on-a-Chip Implementing Renal Proximal Tubular Function In Vitro	12
Erratum: A 3D Microfluidic Model of Initial Lymphatic Vessels for Investigating Dendritic Cell Chemotaxis Under Inflammatory Condition	12
Advancements in Kidney-on-Chip: Antibiotic-Induced Kidney Injury and Future Directions	12
Surface Plasmon Resonance (SPR) Biosensor for the Detection of SARS-CoV-2 Using Autodisplyaed FV-antibodies on Outer Membrane of E. coli	11
Advances and Challenges in 3D Modelling of Organ-on-a-Chip Devices with a Focus on the Glomerular Basement Membrane (GBM) and Tubular Systems: A Critical Review	11
Oxygen-Terminated Silicon Carbide (SiC) Particle-Coated Electrodes for Highly Sensitive Electrochemical Immunoassays	11
Simultaneous Triplex Detection in a Single-Test-Line Lateral Flow Immunoassay Utilizing Distinct Nanoparticle Colorimetry	11
Development of Gut-Mucus Chip for Intestinal Absorption Study	11
Modular Microfluidics: A Systematic Review of Assembly-Based Categorization and Biological Applications	10
Rapid and Cost-Effective On-site Detection of Plant Viruses Using Personal Glucose Meters Integrated with LAMP and Cascade Enzymatic Reactions	10
Advanced Microfluidic Platform for Tumor Spheroid Formation and Cultivation Fabricated from OSTE+ Polymer	9

Mechanically Flexible Polymeric Nanoneedle Arrays for Promoting Differentiation and Functional Activity of Neural Progenitor Cells	9
Lateral Flow Assay System Using Glycerol-Stabilized Fluorescent Copper Nanoclusters as Detection Labels	9
Microtubule WGM Sensor: Applications and Key Technologies	9
Recent Advances in Electrochemical and Nanophotonic Biosensors for SARS-CoV-2 Detection	9
Nanomaterials-Based Exosomes for the Diagnostics and Drug Deliveries of Central Nervous System Diseases	8
Hydrogel Sensors for Wound Monitoring: Mechanisms, Applications, and Clinical Translation	8
Exploring the Role of Shape and Size in Metal–Organic Framework–Mediated Ferroptosis	8
Immunogenicity Monitoring Cell Chip Incorporating Finger-Actuated Microfluidic and Colorimetric Paper-Based Analytical Functions	8
A Robust, Solvent-Resistant Paper-Based Platform for Discriminative Detection of Organic Solvents	8
Fluorescent Lateral Flow Assay with Carbon Nanodot Conjugates for Carcinoembryonic Antigen	8
Engineering Myocardial Anisotropy to Model Electrical Dysfunction and Pharmacological Responsiveness in Arrhythmogenic Cardiomyopathy	8
Fabrication of Biomimetic Cell Culture Membranes Using Robust and Reusable Nickel Micropillar Molds	7
Micro-injection Molded Droplet Generation System for Digital PCR Application	7
Highly Efficient DNA Reporter for CRISPR/Cas12a-Based Specific and Sensitive Biosensor	7
Next-Generation Human Biofluid Diagnostics Enabled by AI-Integrated SERS Biosensors	7
Vertical Droplet-Squeezing Platform for Highly Efficient Biomolecular Delivery	7
Effect of Periodical Tensile Stimulation on the Human Skin Equivalents by Magnetic Stretching Skin-on-a-Chip (MSSC)	7
Multiplex Magnetic Biosensor Microarrays Facilitate Personalized Vaccination Schedules for SARS-CoV-2 Variants	7
Paper-Based Radial Flow Assay Integrated to Portable Isothermal Amplification Chip Platform for Colorimetric Detection of Target DNA	7
Integration of Machine Learning in Surface-Enhanced Raman Spectroscopy Biosensor for Biomedical Applications	6
Advanced Organotypic In Vitro Model Systems for Host–Microbial Coculture	6
Investigation of Collagen Network Microstructure and Vascular Sprouting On-Chip Using Non-enzymatic Glycation	6
Voltammetric Aptamer-Based Biochip Featuring Poly Gallic Acid/SnO2–MoO3 Nanocomposite for Selective Tryptophan Detection: Potential Application in Alzheimer's Diagnosis	6
Point-of-Care Diagnostic Modular Device for Detection of VHSV with Reverse Transcription Loop-Mediated Isothermal Amplification	6
Label-Free Impedance Monitoring of the Protective Effect of Salviae Miltiorrhizae Radix on Glutamate-Induced Neurotoxicity	6
Microfluidic Capture Device for Simple, Cell Surface Marker-Based Quantification of Senescent CD8+ T Cells	5
Intensity Histogram-Based Reliable Image Analysis Method for Bead-Based Fluorescence Immunoassay	5
Flexible Capillary Microfluidic Devices Based on Surface-Energy Modified Polydimethylsiloxane and Polymethylmethacrylate with Room-Temperature Chemical Bonding	5
One-Step Immunoassay for the Detection of Influenza Virus Based on Screened Nucleoprotein (NP)-like Mimotopes from Fv-Antibody Library	5
Electrochemical Immunoassay Using Diffusion Layer Dispersion Effect of Electrodes	5
Flexible Polytetrafluoroethylene (PTFE) Tube-Based Curved Serpentine Micromixer Guided by 3D-Printed Frames	5
Stabilized Exfoliated Black Phosphorus Nanosheets for Fungal DNA-Extraction Assay	5
Fabrication of Cell Spheroids for 3D Cell Culture and Biomedical Applications	5
Comparison and Analysis of Polymer-Functionalized Carbon Nanotubes for Enhancement of the Quantitative Detection of Procalcitonin Levels in Human Plasma	5
Horizontal Viscoelastic Focusing for Hyperspectral Microflow Cytometry	5
Gut-Liver-Immune Modular Multi-organ Chip for Non-alcoholic Fatty Liver Disease (NAFLD) Model	5
Toxicity Assessment of Humidifier Disinfectant Component CMIT/MIT Using Bioprinted Thin-Layer Human Alveolar Model	5
Optical-Switch Raman Spectroscopy for High Throughput Screening	5
Enhanced Antitumor Effect of the Combination of Bacille Calmette-Guérin and an Immune Checkpoint Inhibitor in Bladder Cancer-On-a-Chip	5
Laser-Assisted Recovery of On-Chip Phage Viral DNA for Phage Fluorescence Immunoassay Microchip	5