OOIR: Observatory of International Research

Papers

(The median citation count of Biochip Journal is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
One-Step Evaluation of Doxorubicin Toxicity Through Concentration Gradient Generator Integrating Breast Cancer-on-a-Chip	66
Non-invasive Thermohydrodynamic Approach for Fast Cell Manipulation at the Microscale	52
Acoustofluidic Microbioreactor Using Surface Acoustic Wave-induced Acoustic Streaming Flow	39
Isolation of Antibodies Against the Spike Protein of SARS-CoV from Pig Serum for Competitive Immunoassay	36
Nanomaterials-Based Exosomes for the Diagnostics and Drug Deliveries of Central Nervous System Diseases	36
A Dual Functional Conductive Hydrogel Containing Titania@Polypyrrole-Cyclodextrin Hybrid Nanotubes for Capture and Degradation of Toxic Chemical	32
Laser-Assisted Recovery of On-Chip Phage Viral DNA for Phage Fluorescence Immunoassay Microchip	30
Recent Developments in Surface Topography-Modulated Neurogenesis	29
Ultraviolet Fluorescence-Based Quantitative Detection of Polycyclic Aromatic Hydrocarbons	29
Effect of Food Sensitivity on Overweight Assessed Using Food-Specific Serum Immunoglobulin G Levels	28
Microfabricated Stretching Devices for Studying the Effects of Tensile Stress on Cells and Tissues	27
Recent Developments in MXene-Based Enzyme-Free Electrochemical Glucose Sensing	24
Proteins Derived from Cnidium officinale Makino React with Serum IgE of Allergic Patients and Stimulate ERK/NF-kB Activation in Human Mast Cell Line HMC-1 Cells	24
Real-Time Detection of SARS-CoV-2 Nucleocapsid Antigen Using Data Analysis Software and IoT-Based Portable Reader with Single-Walled Carbon Nanotube Field Effect Transistor	23
Electrochemical Microbiosensor for Detecting COVID-19 in a Patient Sample Based on Gold Microcuboids Pattern	23
DNA–Gold Nanoparticle Conjugates for Intracellular miRNA Detection Using Surface-Enhanced Raman Spectroscopy	23
Development of Multi-HRP-Conjugated Branched PEI/Antibody-Functionalized Gold Nanoparticles for Ultra-Sensitive ELISA	22
Microfluidic Capture Device for Simple, Cell Surface Marker-Based Quantification of Senescent CD8+ T Cells	22
Classification of DNA Mixtures by Nanoelectrokinetic Driftless Preconcentration	21
Microphysiological Systems as Organ-Specific In Vitro Vascular Models for Disease Modeling	21
A Laser-Micromachined PCB Electrolytic Micropump Using an Oil-Based Electrolyte Separation Barrier	20
Modeling Preeclampsia: From 2D Cultures to Placenta-on-a-Chip Technologies	20
SF-qPCR: Strand Displacement-Based Fast Quantitative Polymerase Chain Reaction	19
Fluorescent Lateral Flow Assay with Carbon Nanodot Conjugates for Carcinoembryonic Antigen	19
Pressed Lateral Flow Assay Strips for Flow Delay-Induced Signal Enhancement in Lateral Flow Assay Strips	19

Microfluidic Device to Maximize Capillary Force Driven Flows for Quantitative Single-Molecule DNA Analysis	19
Immunogenicity Monitoring Cell Chip Incorporating Finger-Actuated Microfluidic and Colorimetric Paper-Based Analytical Functions	19
Transdermal Drug Delivery System Using Light and Moisture Dual Responsive Hybrid Microneedles	18
Target-Responsive Template Structure Switching-Mediated Exponential Rolling Circle Amplification for the Direct and Sensitive Detection of MicroRNA	18
An Integrated Electrochemical Sensor with Flexible Microfluidic Structures for Human Sweat Analysis	17
Recording Fast Ion Channel Kinetics Using Non-invasive Electrical Impedance Spectroscopy	17
Recent Developments in 3D Printing of Droplet-Based Microfluidics	16
Reduction of Erythrocyte Fluid Adaptability Due to Cell Membrane Hardening Based on Single-Cell Analysis	16
Alteration of Inertial Focusing Positions in Triangular Channels Using Flexible PDMS Microfluidics	15
Nanoplasmonic Sensor Chip Readable in a Conventional Plate Reader	15
The Novel Membrane-Type Micro-system to Assess the Bonus Effect of Physiological and Physical Stimuli on Bone Regeneration	15
Anti-SARS-CoV-2 Nucleoprotein Antibodies Derived from Pig Serum with a Controlled Specificity	14
Recent Advances in Electrochemical and Optical Biosensors for Cancer Biomarker Detection	13
Portable Au Nanoparticle-Based Colorimetric Sensor Strip for Rapid On-Site Detection of Cd2+ Ions in Potable Water	13
All-Rounder Liposomes in Cancer Immunotherapy: Strategies and Design Applications of Engineered Liposomal Nanomaterials	13
One-Step Immunoassay for the Detection of SARS-CoV-2 Nucleocapsid Protein Using Screened Fv-Antibodies	12
Numerical-Simulation-Based Buffer Design for Microchip Electrophoresis with Capacitively Coupled Contactless Conductivity Detection	12
3D Artificial Cell Membranes as Versatile Platforms for Biological Applications	12
Understanding Confounding Effects of Blood Handling Strategies on RNA Quality and Transcriptomic Alteration Using RNA Sequencing	12
Colorimetric Detection of Staphylococcus aureus Based on Direct Loop-Mediated Isothermal Amplification in Combination with Lateral Flow Assay	12
Enzymatic Reaction Automation in Nanodroplet Microfluidic for the Quality Control of Monoclonal Antibodies	12
Ultrasensitive Detection of Ovarian Cancer Biomarker Using Au Nanoplate SERS Immunoassay	11
Recent Advances in 3D-Cultured Brain Tissue Models Derived from Human iPSCs	11
Analysis of Thrombosis Formation and Growth Using Microfluidic Chips and Multiphase Computational Fluid Dynamics	11
Advancing Blood–Brain Barrier-on-a-Chip Models Through Numerical Simulations	10
Surface Modification Strategies for Biomedical Applications: Enhancing Cell–Biomaterial Interfaces and Biochip Performances	10
Recent Progress in Rapid Biosensor Fabrication Methods: Focus on Electrical Potential Application	10
Surface Tension-Based Open Microfluidic Platform Using Micropillars to Recreate the 3D Lung Cellular Microenvironment	10
Recent Developments in Innovative Magnetic Nanoparticles-Based Immunoassays: From Improvement of Conventional Immunoassays to Diagnosis of COVID-19	10
Synthesis of Truncated DNA Aptamer and Its Application to an Electrochemical Biosensor Consisting of an Aptamer and a MXene Heterolayer for Yellow Fever Virus	9
Development of an Electrochemical Biosensor for Tetrodotoxin Using Specific Binding Peptide on Polypyrrole/Au Nanoparticle-Modified Electrodes	9
Multi-layered Microfluidic Drug Screening Platform Enabling Simultaneous Generation of Linear and Logarithmic Concentration Gradients	9
In Vitro Assays of Neurite Outgrowth and Synapse Formation Using Thermoplasmonic Ablation Technique	9
Graphene Oxide-Mediated Fluorometric Aptasensor for Okadaic Acid Detection	9
Towards Nanomaterial-Incorporated Soft Actuators: from Inorganic/Organic Material-Based Soft Robot to Biomaterial-Based Biohybrid Robot	9
Enhancement of Overlimiting Current in a Three-Dimensional Hierarchical Micro/Nanofluidic System by Non-uniform Compartmentalization	9
Rapid and Ultrasensitive Detection of Staphylococcus aureus Using a Gold-Interdigitated Single-Wave-Shaped Electrode (Au-ISWE) Electrochemical Biosensor	8
Biosensing Technologies for Chronic Diseases	8
Multistory Stairs-based, Fast and Point-of-care Testing for Disease Biomarker Using One-step Capillary Microfluidic Fluoroimmunoassay Chip via Continuous On-chip Labelling	8
Recent Advances in Microfluidic-Based Microphysiological Systems	8
Combining Ultrasound-Mediated Intracellular Delivery with Microfluidics in Various Applications	8
Quantitative Determination of 3D-Printing and Surface-Treatment Conditions for Direct-Printed Microfluidic Devices	8
Deep Learning-Assisted Droplet Digital PCR for Quantitative Detection of Human Coronavirus	8
Single-Shot Light-Field Microscopy: An Emerging Tool for 3D Biomedical Imaging	8
Micro-injection Molded Droplet Generation System for Digital PCR Application	7
A Controlled Transcription-Driven Light-Up Aptamer Amplification for Nucleoside Triphosphate Detection	7
Development of Tumor-Vasculature Interaction on Chip Mimicking Vessel Co-Option of Glioblastoma	7
Floating Magnetic Membrane for Rapid Enrichment of Pathogenic Bacteria	7
Synergetic Chemo-Mechano Antimicrobial Puncturable Nanostructures for Efficient Bioaerosol Removal	7
Low-Powered pH-Stable Nano-electrokinetically Enhanced Lateral Flow Assay for COVID-19 Antigen Test	7

Systematically Studying Dissolution Process of 3D Printed Acrylonitrile Butadiene Styrene (ABS) Mold for Creation of Complex and Fully Transparent Polydimethylsiloxane (PDMS) Fluidic Devices	7
Development of an Inkless, Visual Volumetric Chip Operated with a Micropipette	7
Biological Influence of Pulmonary Disease Conditions Induced by Particulate Matter on Microfluidic Lung Chips	6
Liquid Crystal-Based Droplet Sensor for the Detection of Hg(II) Ions Using an Aptamer as the Recognition Element	6
Effect of Periodical Tensile Stimulation on the Human Skin Equivalents by Magnetic Stretching Skin-on-a-Chip (MSSC)	6
Recent Advances in Photoelectrochemical Sensing of Alzheimer’s Biomarkers	6
Highly Efficient DNA Reporter for CRISPR/Cas12a-Based Specific and Sensitive Biosensor	5
Paper-Based Radial Flow Assay Integrated to Portable Isothermal Amplification Chip Platform for Colorimetric Detection of Target DNA	5
Neuroscience Research using Small Animals on a Chip: From Nematodes to Zebrafish Larvae	5
A Microfluidic Stretch System Upregulates Resistance Exercise-Related Pathway	5
Voltammetric Aptamer-Based Biochip Featuring Poly Gallic Acid/SnO2–MoO3 Nanocomposite for Selective Tryptophan Detection: Potential Application in Alzheimer's Diagnosis	5
Competitive Immunoassay of SARS-CoV-2 Using Pig Sera-Derived Anti-SARS-CoV-2 Antibodies	5
Magnetic Nanochain-Based Smart Drug Delivery System with Remote Tunable Drug Release by a Magnetic Field	5
Fabrication of Biomimetic Cell Culture Membranes Using Robust and Reusable Nickel Micropillar Molds	5
The Detection of Urinary Exosomal miRNAs for Cancer Diagnostics and Prognostics	5
Recent Progress in High-Throughput Enzymatic DNA Synthesis for Data Storage	5
Development of a Structure-Switching Aptamer for Sensitive Colorimetric Detection of Botulinum Neurotoxin	5
Thermoplasmonic Scaffold Design for the Modulation of Neural Activity in Three-Dimensional Neuronal Cultures	5
Machine Learning-Driven Electrochemical Aptasensing Platform for Highly Accurate Prediction of Phthalate Concentration in Multiple River Sites	5