OOIR: Observatory of International Research

Papers

(The H4-Index of Gut Microbes is 77. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Microbial succinate promotes the response to metformin by upregulating secretory immunoglobulin a in intestinal immunity	403
Decoding the HMO‒microbiome axis: bridging maternal milk to infant health outcomes	403
Exercise improves gut microbial metabolites in an intensity-dependent manner: a pooled analysis of randomized controlled trials	391
Akkermansia muciniphila reduces susceptibility to Listeria monocytogenes infection in mice fed a high-fat diet	332
Gut microbiota and tuberculosis infection: interaction and therapeutic potential	322
The gut-joint axis mediates the TNF-induced RA process and PBMT therapeutic effects through the metabolites of gut microbiota	282
Limosilactobacillus reuteri DS0384 promotes intestinal epithelial maturation via the postbiotic effect in human intestinal organoids and infant mice	240
Gut microbiota in nonalcoholic fatty liver disease: a PREDIMED-Plus trial sub analysis	232
Modeling spatial interaction networks of the gut microbiota	202
Human milk oligosaccharide metabolism and antibiotic resistance in early gut colonizers: insights from bifidobacteria and lactobacilli in the maternal-infant microbiome	190
Gut microbial features and dietary fiber intake predict gut microbiota response to resistant starch supplementation	187
Microbiota during pregnancy and early life: role in maternal−neonatal outcomes based on human evidence	184
L. rhamnosus CNCM I-3690 survival, adaptation, and small bowel microbiome impact in human	180
A high fiber diet or supplementation with Lactococcus lactis subspecies cremoris to pregnant mice confers protection against intestinal injury in adult offspring	171
Children’s gut microbiota predicts the efficacy of obesity treatment	155
Antigenic operon fragmentation and diversification mechanism in Bacteroidota impacts gut metagenomics and pathobionts in Crohn's disease microlesions	145
Pasteurized Akkermansia muciniphila improves irritable bowel syndrome-like symptoms and related behavioral disorders in mice	138
Intestinal TLR4 deletion exacerbates acute pancreatitis through gut microbiota dysbiosis and Paneth cells deficiency	137
Recipient microbiome-related features predicting metabolic improvement following fecal microbiota transplantation in adults with severe obesity and metabolic syndrome: a secondary analysis of a phase	136
Dietary fiber-based regulation of bile salt hydrolase activity in the gut microbiota and its relevance to human disease	133
The ladder of regulatory stringency and balance: an application to the US FDA’s regulation of bacterial live therapeutics	127
Late-onset sepsis treatment in very preterm infants alters longitudinal microbiome trajectory with lower abundance of Bifidobacterium despite probiotic s	127
Opioid-induced dysbiosis of maternal gut microbiota during gestation alters offspring gut microbiota and pain sensitivity	126
Depletion of butyrate-producing microbes of the Firmicutes predicts nonresponse to FMT therapy in patients with recurrent Clostridium difficile infection	125
Gut microbes mediate the synergistic effects of dietary cholesterol and saturated fat in driving fibrosing MASH	124

Clostridioides difficile aggravates dextran sulfate solution (DSS)-induced colitis by shaping the gut microbiota and promoting neutrophil recruitment	124
Linking serum vitamin D levels with gut microbiota after 1-year lifestyle intervention with Mediterranean diet in patients with obesity and metabolic syndrome: a nested cross-sectional and prospective	122
Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values	120
Escherichia coli triggers α-synuclein pathology in the LRRK2 transgenic mouse model of PD	120
Meta-analysis reveals Helicobacter pylori mutual exclusivity and reproducible gastric microbiome alterations during gastric carcinoma progression	120
Bile salt hydrolase activity as a rational target for MASLD therapy	120
Metabolic modeling links gut microbiota to metabolic markers of Parkinson’s disease	118
Intestinal bacteria and colorectal cancer: etiology and treatment	118
3'-Sialyllactose and B. infantis synergistically alleviate gut inflammation and barrier dysfunction by enriching cross-feeding bacteria for short-chain f	113
Effect of diet on the evolution of gut commensal bacteria	113
Lactococcus lactis subsp. Cremoris reprograms systemic metabolism and protects against myocardial injury	111
Lactobacillus acidophilus ameliorates cholestatic liver injury through inhibiting bile acid synthesis and promoting bile acid excretion	111
Faecal (or intestinal) microbiota transplant: a tool for repairing the gut microbiome	110
Gut microbiota metabolite indole-3-acetic acid maintains intestinal epithelial homeostasis through mucin sulfation	109
Gut microbiota-mediated conversion of mangiferin to norathyriol alters short chain fatty acid and urate metabolism	108
Citrobacter rodentium possesses a functional type II secretion system necessary for successful host infection	107
Gluten-free diet affects fecal small non-coding RNA profiles and microbiome composition in celiac disease supporting a host-gut microbiota crosstalk	106
The Fe-S cluster biosynthesis in Enterococcus faecium is essential for anaerobic growth and gastrointestinal colonization	104
Helicobacter pylori activates histone lactylation to promote gastric cancer progression and immune evasion through the HAS2/c-MYC/PD-L1 axis	103
Ethanol-induced changes to the gut microbiome compromise the intestinal homeostasis: a review	102
Microbial extracellular vesicles from min pigs remodel macrophage polarization via STING to sustain intestinal immune homeostasis	102
Washed microbiota transplantation promotes homing of group 3 innate lymphoid cells to the liver via the CXCL16/CXCR6 axis: a potential treatment for metabolic-associated fatty liver disease	100
Maternal gut microbiota mediates prenatal stress-induced fetal blood‒brain barrier dysfunction	97
Maternal milk fat globule membrane enriched gut L. murinus and circulating SCFAs to improve placental efficiency and fetal development in intrauterine gr	96
Gut microbiota drives structural variation of exogenous probiotics to enhance colonization	96
Comparison of gnotobiotic communities reveals milk-adapted metabolic functions and unexpected amino acid metabolism by the pre-weaning microbiome	94
Gut virome profiling identifies an association between temperate phages and colorectal cancer promoted by Helicobacter pylori infection	93
Dietary fiber guar gum-induced shift in gut microbiota metabolism and intestinal immune activity enhances susceptibility to colonic inflammation	92
Unraveling multiple sclerosis: a hidden interaction between intestinal microbiota and host lipid metabolism	91
Role and mechanism of gut microbiota and metabolites in schizophrenia complicated with sleep disorder	89
High throughput genome scale modeling predicts microbial vitamin requirements contribute to gut microbiome community structure	89
The crystal structure of the toxin EspC from enteropathogenic Escherichia coli reveals the mechanism that governs host cell entry and cytotoxicity	88
Regulation of flagellar motility and biosynthesis in enterohemorrhagic Escherichia coli O157:H7	87
Therapeutic potential of Clostridium butyricum anticancer effects in colorectal cancer	87
Obesity enriches for tumor protective microbial metabolites and treatment refractory cells to confer therapy resistance in PDAC	86
Proton pump inhibitors are not associated with an increased risk of Clostridioides difficile infection: a systematic review and meta-analysis of randomiz	86
Advances in the acting mechanism and treatment of gut microbiota in metabolic dysfunction-associated steatotic liver disease	85
Age-associated temporal decline in butyrate-producing bacteria plays a key pathogenic role in the onset and progression of neuropathology and memory deficits in 3×Tg-AD mice	84
Efficacy of fecal microbiota transplantation in patients with Parkinson’s disease: clinical trial results from a randomized, placebo-controlled design	83
The microbiota and the host organism switch between cooperation and competition based on dietary iron levels	83
The intestinal microbiome of inflammatory bowel disease across the pediatric age range	83
The gut microbiome in graft-versus-host disease: mechanisms of immune modulation and therapeutic approaches	81
The regulatory effect of chitooligosaccharides on islet inflammation in T2D individuals after islet cell transplantation: the mechanism behind Candida albicans	81
Feeding microbes to feed the Gut: inulin reprograms intestinal epithelial metabolism and proliferation through HIF1α	81
Antidepressant drugs promote the spread of broad-host-range plasmid in mouse and human gut microbiota	81
Exploring the gut microbiome and metabolomic interactions of antimetabolite drugs to optimize therapy	80
In vivo systematic analysis of microbiota-prebiotic crosstalk reveals a synbiotic that effectively ameliorates DSS-induced colitis in mice	79
Immunoglobulin A protease from Sutterella wadsworthensis modifies outcome of infection with Campylobacter jejuni	79
Candida albicans can foster gut dysbiosis and systemic inflammation during HIV infection	79
Gut microbiome diversity, variability, and latent community types compared with shifts in body weight during the freshman year of college in dormitory-housed adolescents	78

Engineered bacteria as an orally administered anti-viral treatment and immunization system	78
Gut microbiota and radiation-induced injury: mechanistic insights and microbial therapies	77
Obesity is the main driver of altered gut microbiome functions in the metabolically unhealthy	77