ACS Chemical Neuroscience

Papers
(The TQCC of ACS Chemical Neuroscience is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Neurochemical and Morphological Comparisons of Motor Nerve Organoids and Spinal-Cord Explants205
Synthesis and Evaluation of Benzylic 18F-Labeled N-Biphenylalkynyl Nipecotic Acid Derivatives for PET Imaging of GABA Transporter 1176
Correction to “Pharmacological Characterizations of anti-Dementia Memantine Nitrate via Neuroprotection and Vasodilation in Vitro and in Vivo149
Dl-3-n-Butylphthalide Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion: Associations with Mitochondrial Permeability Transition Pore Closure and Suppression of Excessive Mitoph120
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Silymarin-Based Nanosheets Efficiently Protect Mitochondria against Oxidative Damage Mediated by α-Synuclein Amyloid Aggregates63
FPT, a 2-Aminotetralin, Is a Potent Serotonin 5-HT1A, 5-HT1B, and 5-HT1D Receptor Agonist That Modulates Cortical Electroencephalogram Activity in Adult Fmr1 Kn56
Caffeine and Nicotine with N-Substituted Diazirine Photoaffinity Labels Form Adducts at Tyrosine-39 of α-Synuclein56
Impaired Dopamine Release and Latent Learning in Alzheimer’s Disease Model Zebrafish53
All Hands on Deck: We Need Multiple Approaches To Uncover the Neuroscience behind the Opioid Overdose Crisis51
Study on the Difference of Protective Efficacy and Mechanism of Radix Aconiti Coreani and Rhizoma Typhonii in Gerbils with Ischemic Stroke47
Chrysin-Loaded Chitosan Nanoparticle-Mediated Neuroprotection in Aβ1–42-Induced Neurodegenerative Conditions in Zebrafish46
Role of NLRP3 Inflammasome in Post-Spinal-Cord-Injury Anxiety and Depression: Molecular Mechanisms and Therapeutic Implications45
Repurposing Anakinra for Alzheimer’s Disease: The In Vitro and In Vivo Effects of Anakinra on LPS- and AC-Induced Neuroinflammation44
Male-Dominant Effects of Chd8 Haploinsufficiency on Synaptic Phenotypes during Development in Mouse Prefrontal Cortex43
Exploring the Application Potential of α-Synuclein Molecular Probes in Early Diagnosis of Parkinson’s Disease: Focus on Imaging Methods42
Ferroptosis, Pyroptosis, and Cuproptosis in Alzheimer’s Disease42
The Orphan Receptor GPR151: Discovery, Expression, and Emerging Biological Significance42
Targeting Microglial Immunoproteasome: A Novel Approach in Neuroinflammatory-Related Disorders41
Competitive Antagonism of Xylazine on α7 Nicotinic Acetylcholine Receptors and Reversal by Curcuminoids39
Rimota-Gd: Paramagnetic Probe for In Vivo MRI Studies of the Cannabinoid 1 Receptor Distribution in the Mouse Brain38
Unraveling the Interplay of Dopamine, Carbon Monoxide, and Heme Oxygenase in Neuromodulation and Cognition38
Altered Composition of Ceramides and Sphingomyelin Distinctly Modulates the Organizational Landscape and Microdomain Dynamics of Neuronal Plasma Membrane: A Computational Microscopy of Alzheimer’s Bra37
New Multitarget Molecules Derived from Caffeine as Potentiators of the Cholinergic System36
Pathological Mutations D169G and P112H Electrostatically Aggravate the Amyloidogenicity of the Functional Domain of TDP-4336
Synthesis and Neuroprotective Evaluation of Substituted Indanone/Benzofuranone and Piperidine Hybrids36
Enhanced Analgesic Efficacy and Reduced Side Effects of Morphine by Combination with PD-1 Agonist35
Role of Bmal1 and Gut Microbiota in Alzheimer’s Disease and Parkinson’s Disease Pathophysiology: The Probable Effect of Melatonin on Their Association35
JNK3 Overexpression in the Entorhinal Cortex Impacts on the Hippocampus and Induces Cognitive Deficiencies and Tau Misfolding34
Rational Design, Synthesis, and Evaluation of Rofecoxib-Based Photosensitizers for the NIR Imaging and Photo-Oxidization of Aβ Aggregates34
Heteroaggregation of Wild-Type and ALS Mutant SOD134
Distinct m 6 A and m 1 A Responses to Neuronal Depolarization in Cortical Neurons34
Discrimination between Alpha-Synuclein Protein Variants with a Single Nanometer-Scale Pore33
Emerging Frontiers in Conformational Exploration of Disordered Proteins: Integrating Autoencoder and Molecular Simulations32
Microinvasive Probes for Monitoring Electrical and Chemical Neural Activity in Nonhuman Primates31
Phosphoproteomic Analysis of Cortical Tissue from Mice Lacking Both CaMKIIα and CaMKIIβ Identifies Novel In Vivo Substrates31
Disease-Associated Mutations in Tau Encode for Changes in Aggregate Structure Conformation31
Assessing the Multitarget Therapeutic Potential of Novel 9-Aminoacridine Derivatives for Alzheimer’s Disease31
Furanoditerpenes from Spongia (Spongia) tubulifera Display Mitochondrial-Mediated Neuroprotective Effects by Targeting Cyclophilin D30
Synthesis, Pharmacological Characterization, and Binding Mode Analysis of 8-Hydroxy-Tetrahydroisoquinolines as 5-HT7 Receptor Inverse Agonists29
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The Mineralocorticoid Receptor: An Emerging Pharmacotherapeutic Target for Alcohol Use Disorder?27
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Transferrin-Functionalized Chitosan Nanoparticles Enable Intranasal Brain Delivery of Cariprazine with Enhanced Neuropharmacological Efficacy27
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5-HT3 Receptor MX Helix Contributes to Receptor Function26
Development of a Dihydroquinoline–Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor26
The Synergistic Potential of Rationally Designed Phenol-Triazole Derivatives to Attenuate Aβ/Cu2+–Aβ Aggregation and Reactive Oxygen Species26
Distinct Cholesterol Localization in Glioblastoma Multiforme Revealed by Mass Spectrometry Imaging25
Ketogenic Diet for Neonatal Hypoxic–Ischemic Encephalopathy25
Hyperphosphorylation-Mimetic TDP-43 Drives Amyloid Formation and Possesses Neuronal Toxicity at the Oligomeric Stage25
Phytic Acid Maintains Peripheral Neuron Integrity and Enhances Survivability against Platinum-Induced Degeneration via Reducing Reactive Oxygen Species and Enhancing Mitochondrial Membrane Potential25
Reactivity of Olanzapine and Tricyclic Antidepressants on the Protective Effects of Trolox on Lipid Peroxidation Evaluated Using Fluorescence Anisotropy, Electron Paramagnetic Resonance Spectrometry, 25
Exploring the Therapeutic Potential of Ar-tur in Alzheimer Disease: A Cheminformatics, Pharmacokinetics, and System Pharmacology Approach25
Citric Acid-Derived Carbon Quantum Dots Attenuate Paraquat-Induced Neuronal Compromise In Vitro and In Vivo25
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Restricts Inflammatory Progression through Limiting Macrophage Infiltration in DRG and Sciatic Nerve during Diabetic Peripheral Neuropathy25
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Identification of Novel Triazole–Pyrazole Conjugates as Potential Anticonvulsant Agents: Synthesis and Biological Evaluations24
Artificial Neural Networks Coupled with MALDI-TOF MS Serum Fingerprinting To Classify and Diagnose Pathological Pain Subtypes in Preclinical Models24
Prenatal Sevoflurane Exposure Impairs the Learning and Memory of Rat Offspring via HMGB1-Induced NLRP3/ASC Inflammasome Activation24
R -MDDMA is a Safer Analogue of MDMA with Therapeutic Potential24
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Neuroprotective Effects of σ 2 R/TMEM97 Receptor Modulators in the Neuronal Model of Huntington’s Disease24
3D Super-Resolution Imaging of PSD95 Reveals an Abundance of Diffuse Protein Supercomplexes in the Mouse Brain24
Dysregulated Neurotransmission and the Role of Viruses in Alzheimer’s Disease23
Vitamin D Ameliorates Doxorubicin-Induced Cognitive Dysfunction via Modulation of the SFRP1/β-Catenin Axis23
Tricyclic Antidepressants as Prospective α-Synucleinopathy Fighters: Evidence of Protein Binding and Antiaggregation Activity23
Decoding the Relationship between Alzheimer’s Disease and Type-2 Diabetes via the Protein Aggregation Prism23
Neuroprotective Effects of an N-Salicyloyl Tryptamine Derivative against Cerebral Ischemia/Reperfusion Injury23
Cytotoxicity of Amyloid β1–42 Fibrils to Brain Immune Cells23
TRIOL Inhibits Rapid Intracellular Acidification and Cerebral Ischemic Injury: The Role of Glutamate in Neuronal Metabolic Reprogramming23
Rational Design and Evaluation of Rivastigmine-Based Pleiotropic Prodrugs for the Treatment of Alzheimer’s Disease23
Sex-Dependent Behavioral and Biochemical Alterations in a Prenatal Oral Valproic Acid Rat Model of Autism23
Aspartic Acid-Modified Phospholipids Regulate Cell Response and Rescue Memory Deficits in APP/PS1 Transgenic Mice23
Transthyretin Binding Mode Dichotomy of Fluorescent trans-Stilbene Ligands23
Automated, Transferable, and Ethanol-Free Radiosynthesis of [11C]Butanol22
α1 Proline 277 Residues Regulate GABAAR Gating through M2-M3 Loop Interaction in the Interface Region22
Sequence-Dependent Conformational Properties of PGGG Motif in Tau Repeats: Insights from Molecular Dynamics Simulations of Narrow Pick Filament22
Targeting Oxidative Stress in Neurodegenerative Disorders: A Novel Role for PCSK9 Inhibition?22
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Covalent Fragment Inhibits RhoA Activation by Guanine Exchange Factors22
Damage of the Phospholipid Bilayer by Aβ42 at Physiologically Relevant Peptide Concentrations22
Specificity and Promiscuity of Phosphoinositide Lipid Interactions with the Serotonin 1A Receptor: Insights from Submillisecond Coarse-Grain Simulati22
Progress toward Multianalyte Neurochemical Detection: Techniques and Applications22
Role of Necroptosis in Central Nervous System Diseases22
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Monitoring Molecules in Neuroscience22
Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D2 Receptor22
Dopamine Release Impairments Accompany Movement Vigor Deficiency in an Exercise-Induced Fatigue Mouse Model22
MiR-23b-3p Improves Brain Damage after Status Epilepticus by Reducing the Formation of Pathological High-Frequency Oscillations via Inhibition of cx43 in Rat Hippocampus22
Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues22
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Cells Overexpressing ALS-Associated SOD1 Variants Are Differentially Susceptible to CuATSM-Associated Toxicity21
Empirical Analysis of Drug Targets for Nervous System Disorders21
Ratiometric Fluorescent Probe Promotes Trans-differentiation of Human Mesenchymal Stem Cells to Neurons21
Deep Proteome Profiling of Rat Dorsal Striatal Synaptoneurosomes Following Methamphetamine Exposure21
On the Tracks of the Aggregation Mechanism of the PHF6 Peptide from Tau Protein: Molecular Dynamics, Energy, and Interaction Network Investigations21
Effects of Ethanol and Opioid Receptor Antagonists Naltrexone and LY2444296 on the Organization of Cholesterol- and Sphingomyelin-Enriched Plasma Membrane Domains21
Deciphering the Inhibitory Mechanism of ALS-Associated N352S and S352p Variants against TDP-43 Aggregation and Its Destabilization Effect on TDP-43 Protofibrils21
Identifying an Optimal Neuroinflammation Treatment Using a Nanoligomer Discovery Engine21
An S-Shaped Aβ42 Cross-β Hexamer Embedded into a Lipid Bilayer Reveals Membrane Disruption and Permeability21
Neuroprotective Effect of Withaferin Derivatives toward MPP+ and 6-OHDA Toxicity to Dopaminergic Neurons21
Modulation of α-Synuclein Fibrillation and Toxicity by 4-Phenylbutyric Acid20
Combination of Resveratrol and Curcumin with Anti-Amyloid Monoclonal Antibodies Aducanumab and Lecanemab Leads to Greater Inhibition of Amyloid-Beta Aggregation20
Glial Cells and Itch: Possible Targets for Novel Antipruritic Therapies20
Divergent Age-Dependent Conformational Rearrangement within Aβ Amyloid Deposits in APP23, APPPS1, and App NL-F 20
Design and Development of Benzothiazole-Based Fluorescent Probes for Selective Detection of Aβ Aggregates in Alzheimer’s Disease20
The Aromatherapeutic Effects of Herbal Compounds in Inhibiting Metal-Induced Structural Changes in Tau Protein Fibrillar Aggregates19
Characterization of the Novel P2X7 Receptor Radioligand [3H]JNJ-64413739 in Human Brain Tissue19
Synthesis, Labeling, and Biological Evaluation of P2Y12 Receptor Radioligands for Positron Emission Tomography Imaging of Neuroinflammation19
A Small Molecule Stabilizes the Disordered Native State of the Alzheimer’s Aβ Peptide19
Classics in Chemical Neuroscience: Tianeptine19
Prussian Blue Nanozyme Treatment of Ischemic Brain Injury via Reducing Oxidative Stress Inhibits Inflammation, Suppresses Apoptosis, and Promotes Neurological Recovery19
Small-Molecule Cdc25A Inhibitors Protect Neuronal Cells from Death Evoked by NGF Deprivation and 6-Hydroxydopamine19
Lipopolysaccharide Effects on Neurotransmission: Understanding Implications for Depression19
N -Benzyl-tryptamine Derivatives as Serotonin 5-HT 2A Receptor (5-HT 2A 18
Dopaminergic Modulation and Computational ADMET Insights for the Antidepressant-like Effect of N-(3-(Phenylselanyl)prop-2-yn-1-yl)benzamide18
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Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model18
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Hydrogen Sulfide–Releasing Insulin Polypeptide Mitigates Hyperglycemia-Induced Neurotoxicity and Cognitive Deficits In Vivo18
Short-Term Administration of Common Anesthetics Does Not Dramatically Change the Endogenous Peptide Profile in the Rat Pituitary18
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Zalsupindole: A Non-Hallucinogenic Psychoplastogen Advancing Psychedelic-Inspired Therapeutics18
Polyglutamine (PolyQ) Diseases: Navigating the Landscape of Neurodegeneration18
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Benzo[d]imidazole-pyrrolo[1,2-a]pyrazine Hybrids Ameliorate Amyloid Aggregates in the Brain of Alzheimer Transgenic Mice18
Synthesis and Preclinical Evaluation of 22-[18F]Fluorodocosahexaenoic Acid as a Positron Emission Tomography Probe for Monitoring Brain Docosahexaenoic Acid Uptake Kinetics18
Edge Substitution Effects of Histidine Tautomerization Behaviors on the Structural Properties and Aggregation Properties of Aβ(1–42) Mature Fibril17
Saroglitazar Enhances Memory Functions and Adult Neurogenesis via Up-Regulation of Wnt/β Catenin Signaling in the Rat Model of Dementia17
Dynamic Spatial Metabolomics Reveals Region-Specific Metabolic Reprogramming and Markers during Vascular Cognitive Impairment Progression17
Discovery of Pre-Clinical Candidate VU6008055/AF98943: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M4 Muscarinic Acetylcholine Receptor Positi17
Determination of Trends Underlying Aspartic Acid Isomerization in Intact Proteins Reveals Unusually Rapid Isomerization of Tau17
Melatonin Relieves Paclitaxel-Induced Neuropathic Pain by Regulating pNEK2-Dependent Epigenetic Pathways in DRG Neurons17
Single-Molecule Fingerprinting Reveals Different Growth Mechanisms in Seed Amplification Assays for Different Polymorphs of α-Synuclein Fibrils17
Hemispheric Utilization of Alpha Oscillatory Dynamics as a Unique Biomarker of Neural Compensation in Females with Fragile X Syndrome17
Rewiring Receptor Activation: Mechanistic Insights into Toggle Switch Modulation by 25CN-NBx Compounds17
Regulation of Dopamine Release by Tonic Activity Patterns in the Striatal Brain Slice17
Proteome Aggregation in Cells Derived from Amyotrophic Lateral Sclerosis Patients for Personalized Drug Evaluation17
Neurotrophic Activity and Its Modulation by Zinc Ion of a Dimeric Peptide Mimicking the Brain-Derived Neurotrophic Factor N-Terminal Region17
Santonin Attenuates Alzheimer’s-Like Pathology via Multitarget Modulation of the NLRP3 Inflammasome, BDNF Signaling, and Amyloidogenic Pathways: An Integrated Experimental and Computational Study17
Deciphering the Inhibitory Mechanism of Naphthoquinone–Dopamine on the Aggregation of Tau Core Fragments PHF6* and PHF617
Evaluation of Alpha-Synuclein and Tau Antiaggregation Activity of Urea and Thiourea-Based Small Molecules for Neurodegenerative Disease Therapeutics17
A Review of Alpha-2 Adrenergic Agents Implicated in Opioid Use Disorder17
Doubly Constrained C-terminal of Roc (COR) Domain-Derived Peptides Inhibit Leucine-Rich Repeat Kinase 2 (LRRK2) Dimerization16
Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Adenosine in the Control of Behavioral and Electrophysiological Modifications Caused by Chronic Stress16
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Molecular Insights into the Dynamics of Amyloid Fibril Growth: Elongation and Lateral Assembly of GNNQQNY Protofibrils16
The Interplay between MiR-134/BDNF and LKB1/AMPK/SIRT1 Accentuates the Antidepressant Efficacy of Empagliflozin in Ovariectomized Rats16
Synthesis and Preclinical Evaluation of Fluorinated 5-Azaindoles as CB2 PET Radioligands16
The Aggregation Continuum of α-Synuclein and Its Relevance to Brain Aging16
Guanidine Derivative ADS1017, a Potent Histamine H3 Receptor Antagonist with Promising Analgesic Activity and Satisfactory Safety Profile16
TMEM106B Fibrils from FTLD Patients and Healthy Controls16
Correction to “Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor”16
Exploring the Therapeutic Potential of Benfotiamine in a Sporadic Alzheimer’s-Like Disease Rat Model: Insights into Insulin Signaling and Cognitive function16
1H NMR Metabolomics and Lipidomics To Monitor Positive Responses in Children with Autism Spectrum Disorder Following a Guided Parental Intervention: A Pilot Study16
Dysregulation of Neuropeptide and Tau Peptide Signatures in Human Alzheimer’s Disease Brain16
New Alpha9 nAChR Ligands Based on a 5-(Quinuclidin-3-ylmethyl)-1,2,4-oxadiazole Scaffold16
Calycosin Inhibit PANoptosis and Alleviate Brain Damage: A Bioinformatics and Experimental Verification Approach16
Monitoring Fast Synaptic Transmission of Neuromodulatory Transmitters To Define Drug Effects in the Brain16
Bicuculline and Bumetanide Attenuate Sevoflurane-Induced Impairment of Myelination and Cognition in Young Mice16
Shared and Unique Disease Pathways in Amyotrophic Lateral Sclerosis and Parkinson’s Disease Unveiled in Peripheral Blood Mononuclear Cells16
Allopregnanolone Regulation of Phasic Dopamine Release and Motivated Behavior16
Potential of ADAM 17 Signal Peptide To Form Amyloid Aggregates in Vitro16
Red-Light-Photosensitized Tyrosine 10 Nitration of β-Amyloid1–42 Diverts the Protein from Forming Toxic Aggregates15
Propionate Aggravates Anxiety and Cognitive Dysfunction in High-Fat Diet Mice by Activating Hippocampal Microglia-Mediated Neuroinflammation15
Restoring Brain Function in Autism: GSK3β Inhibition by 6-Bromoindirubin-3′-oxime Reverses Valproic Acid-induced Neuropathology15
Kappa Opioid Receptor Activation Induces Epigenetic Silencing of Brain-Derived Neurotropic Factor via HDAC5 in Depression15
Role of Imaging Modalities and N -Acetylcysteine Treatment in Sepsis-Associated Encephalopathy15
Design, Synthesis, and Pharmacological Evaluation of N-Propargylated Diphenylpyrimidines as Multitarget Directed Ligands for the Treatment of Alzheimer’s Disease15
Longitudinal PET Imaging of the Effects of a D 2 Dopamine Receptor Antisense Oligonucleotide15
Griess’s Reagent-Based Azo Compounds Ameliorate Multifaceted Toxicity and Ferroptosis in Alzheimer’s Disease15
Understanding Neuropeptide Transmission in the Brain by Optical Uncaging and Release15
Optical Precise Ablation of Targeted Individual Neurons In Vivo15
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease15
New Insights on Protein Folding and Misfolding: Histidine Behaviors15
Determining Structural Changes for Ligand Recognition between Human and Rat Phosphorylated BACE1 in Silico and Its Phosphorylation by GSK3β at Thr252 by in Vitro Studies15
TEMPOL Enhances Polyethylene Glycol Axon Fusion Following Sciatic Nerve Transection in Adult Rats15
Underlying Causes and Treatment Modalities for Neurological Deficits in COVID-19 and Long-COVID15
Pharmacological Mechanism of the Non-hallucinogenic 5-HT2A Agonist Ariadne and Analogs15
A Transcription Factor ZNF384, Regulated by LINC00265, Activates the Expression of IFI30 to Stimulate Malignant Progression in Glioma15
In Vitro and In Vivo Investigations of Chromone Derivatives as Potential Multitarget-Directed Ligands: Cognitive Amelioration Utilizing a Scopolamine-Induced Zebrafish Model15
Unraveling the Connection of Epstein–Barr Virus and Its Glycoprotein M146–157 Peptide with Neurological Ailments15
Observation of α-Synuclein Preformed Fibrils Interacting with SH-SY5Y Neuroblastoma Cell Membranes Using Scanning Ion Conductance Microscopy15
Dynamic and Rapid Detection of Guanosine during Ischemia15
Serotonin 1A Receptors Modulate Serotonin 2A Receptor-Mediated Behavioral Effects of 5-Methoxy-N,N-dimethyltryptamine Analogs in Mice15
Multi-Target-Directed Triazole Derivatives: Design, Synthesis, and Evaluation of Synergistic Modulation in Alzheimer’s Disease14
Exploring the Structural Order of Condensates Formed by the PRD2 Domain of Mouse CPEB314
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Myelin Sheaths as “Accessories in Clothing” for Individualizing Every Neuron14
Curcumin Reduces Amyloid Beta Oligomer Interactions with Anionic Membranes14
Comprehensive Characterization of a Systematic Library of Alkyl and Alicyclic Synthetic Cannabinoids Related to CUMYL-PICA, CUMYL-BUTICA, CUMYL-CBMICA, and CUMYL-PINACA14
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Characterization of (R)- and (S)-[18F]OF-NB1 in Rodents as Positron Emission Tomography Probes for Imaging GluN2B Subunit-Containing N-Methyl-d-Aspartate Rec14
Profiling the Impact of mGlu7/Elfn1 Protein Interactions on the Pharmacology of mGlu7 Allosteric Modulators14
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Psychedelic-like Activity of Norpsilocin Analogues14
Effects of Anesthetic Administration on Rat Hypothalamus and Cerebral Cortex Peptidome14
4-Amino-3′,4′-dihydroxychalcone Increases Tau Dynamics in Phase-Separated Droplets and Inhibits Tau Aggregation14
Fiber Photometry Analysis of Spontaneous Dopamine Signals: The Z -Scored Data Are Not the Data14
Compensatory Contextual Fear Memory Pathways Develop in the Infralimbic Cortex within 3 Days after the First Test in the Absence of the Dorsal Hippocampus14
Exogenous Huntingtin-Exon1 Aggregates Exhibit Distinct Levels of Toxicity to Caenorhabditis elegans14
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Biophysical Characterization and Preformulation Studies of Human Mesencephalic Astrocyte-Derived Neurotropic Factor14
Neuralized1-Mediated CPEB3 Ubiquitination in the Spinal Dorsal Horn Contributes to the Pathogenesis of Neuropathic Pain in Rats14
A Structure–Activity Relationship Study of Novel Positive Allosteric Modulators for the δ-Opioid Receptor14
Key Residue for Aggregation of Amyloid-β Peptides13
Machine Learning-Driven Ensemble Screening of Multitarget Kinase Inhibitors for Tauopathy-Associated Neurodegeneration Using All-Atom and Steered MD Simulations13
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Atomic Force Microscopy Applied to the Study of Tauopathies13
Differential Effects of Nicotine, Alcohol, and Coexposure on Neuroimmune-Related Protein and Gene Expression in Corticolimbic Brain Regions of Rats13
Combinations of Vitamin A and Vitamin E Metabolites Confer Resilience against Amyloid-β Aggregation13
Multivalent Gd-DOTA Decorated Oligopeptide as Sensitive MRI Molecular Probes for In Vivo Imaging of Brain Connectivity13
Functional Characterization of an Arylsulfonamide-Based Small-Molecule Inhibitor of the NLRP3 Inflammasome13
Quantitative Analysis of Neuropeptide Y (NPY) and C-Terminal Glycine-Extended NPY by Mass Spectrometry and Their Localization in the Developing and Sexual Adult Mouse Brains13
Stereospecific Properties and Intracellular Transport of Novel Intrinsically Fluorescent Neurosteroids13
Hypoxic Preconditioning Modulates BDNF and Its Signaling through DNA Methylation to Promote Learning and Memory in Mice13
Mitochondrial Inhibitor Rotenone Triggers and Enhances Neuronal Ferroptosis Following Intracerebral Hemorrhage13
Targeting GABAergic Hypofunction Associated with Schizophrenia: Identification of α1β2γ2GABA-A Receptor Ligands with Neuroprotective and Antipsychotic Properties13
Comparing Brain and Blood Lipidome Changes following Single and Repetitive Mild Traumatic Brain Injury in Rats13
Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons13
Formation of Calprotectin Inhibits Amyloid Aggregation of S100A8 and S100A9 Proteins13
Translational Significance of GMF-β Inhibition by Indazole-4-yl-methanol in Enteric Glial Cells for Treating Multiple Sclerosis13
Probing Chemical Complexity of Amyloid Plaques in Alzheimer’s Disease Mice using Hyperspectral Raman Imaging13
Short-Chain Fatty Acids in the Microbiota–Gut–Brain Axis: Role in Neurodegenerative Disorders and Viral Infections13
Glycation Produces Topologically Different α-Synuclein Oligomeric Strains and Modulates Microglia Response via the NLRP3-Inflammasome Pathway13
Myricetin: A Potent Anti-Amyloidogenic Polyphenol against Superoxide Dismutase 1 Aggregation13
Substrate Selection Criteria in Regulated Intramembrane Proteolysis13
Repurposing of the PET Probe Prototype PiB for Label and Radiation-Free CEST MRI Molecular Imaging of Amyloid13
Ferroptosis Regulated by 5-HT3a Receptor via Calcium/Calmodulin Signaling Contributes to Neuropathic Pain in Brachial Plexus Avulsion Rat Models13
Impact of Indole Inclusion in the Design of Multi-Tactical Metal-Binding Tetra-Aza Macrocycles that Target the Molecular Features of Neurodegeneration13
Fluorometric Nanoscale Analysis of Bilirubin and Biliverdin in Human Cerebrospinal Fluid13
Imidazo[2,1-b][1,3]thiazine Derivatives as Potential Modulators of Alpha-Synuclein Amyloid Aggregation13
Haloperidol Prevents Oxytosis/Ferroptosis by Targeting Lysosomal Ferrous Ions in a Manner Independent of Dopamine D2 and Sigma-1 Receptors13
Angelic Acid Disassembles Fibrillar α-Synuclein Aggregates through β-Sheet Interface Disruption12
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