OOIR: Observatory of International Research

Papers

(The TQCC of ACS Chemical Neuroscience is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Issue Editorial Masthead	100
Issue Editorial Masthead	100
Issue Editorial Masthead	98
Issue Publication Information	92
JNK3 Overexpression in the Entorhinal Cortex Impacts on the Hippocampus and Induces Cognitive Deficiencies and Tau Misfolding	82
Issue Publication Information	79
Synthesis and Neuroprotective Evaluation of Substituted Indanone/Benzofuranone and Piperidine Hybrids	78
Role of Bmal1 and Gut Microbiota in Alzheimer’s Disease and Parkinson’s Disease Pathophysiology: The Probable Effect of Melatonin on Their Association	77
Issue Publication Information	73
Neurochemical and Morphological Comparisons of Motor Nerve Organoids and Spinal-Cord Explants	64
Targeting Microglial Immunoproteasome: A Novel Approach in Neuroinflammatory-Related Disorders	59
Rational Design, Synthesis, and Evaluation of Rofecoxib-Based Photosensitizers for the NIR Imaging and Photo-Oxidization of Aβ Aggregates	55
FPT, a 2-Aminotetralin, Is a Potent Serotonin 5-HT_1A, 5-HT_1B, and 5-HT_1D Receptor Agonist That Modulates Cortical Electroencephalogram Activity in Adult Fmr1 Kn	53
Role of NLRP3 Inflammasome in Post-Spinal-Cord-Injury Anxiety and Depression: Molecular Mechanisms and Therapeutic Implications	53
Radiosynthesis and In Vivo Evaluation of Four Positron Emission Tomography Tracer Candidates for Imaging of Melatonin Receptors	53
Emerging Frontiers in Conformational Exploration of Disordered Proteins: Integrating Autoencoder and Molecular Simulations	52
Study on the Difference of Protective Efficacy and Mechanism of Radix Aconiti Coreani and Rhizoma Typhonii in Gerbils with Ischemic Stroke	52
Repurposing Anakinra for Alzheimer’s Disease: The In Vitro and In Vivo Effects of Anakinra on LPS- and AC-Induced Neuroinflammation	51
Rimota-Gd: Paramagnetic Probe for In Vivo MRI Studies of the Cannabinoid 1 Receptor Distribution in the Mouse Brain	50
Correction to “Pharmacological Characterizations of anti-Dementia Memantine Nitrate via Neuroprotection and Vasodilation in Vitro and in Vivo”	49
Novel Imidazole Phenoxyacetic Acids as Inhibitors of USP30 for Neuroprotection Implication via the Ubiquitin-Rho-110 Fluorometric Assay: Design, Synthesis, and In Silico and Biochemical Assays	45
Male-Dominant Effects of Chd8 Haploinsufficiency on Synaptic Phenotypes during Development in Mouse Prefrontal Cortex	45
Pathological Mutations D169G and P112H Electrostatically Aggravate the Amyloidogenicity of the Functional Domain of TDP-43	45
Synthesis and Evaluation of Benzylic ¹⁸F-Labeled N-Biphenylalkynyl Nipecotic Acid Derivatives for PET Imaging of GABA Transporter 1	44
Enhanced Analgesic Efficacy and Reduced Side Effects of Morphine by Combination with PD-1 Agonist	43

Repeated Endomorphin Analogue MEL-0614 Reduces Tolerance and Improves Chronic Postoperative Pain without Modulating the P2X7R Signaling Pathway	42
Competitive Antagonism of Xylazine on α7 Nicotinic Acetylcholine Receptors and Reversal by Curcuminoids	42
GPR68 Improves Nerve Damage and Myelination in an Immature Rat Model Induced by Sevoflurane Anesthesia by Activating cAMP/CREB to Mediate BDNF	40
Furanoditerpenes from Spongia (Spongia) tubulifera Display Mitochondrial-Mediated Neuroprotective Effects by Targeting Cyclophilin D	39
Pharmacokinetic Approach to Combat the Synthetic Cannabinoid PB-22	38
New Multitarget Molecules Derived from Caffeine as Potentiators of the Cholinergic System	37
Caffeine and Nicotine with N-Substituted Diazirine Photoaffinity Labels Form Adducts at Tyrosine-39 of α-Synuclein	37
Disease-Associated Mutations in Tau Encode for Changes in Aggregate Structure Conformation	37
Optimized TrkB Agonist Ameliorates Alzheimer’s Disease Pathologies and Improves Cognitive Functions via Inhibiting Delta-Secretase	36
Discrimination between Alpha-Synuclein Protein Variants with a Single Nanometer-Scale Pore	36
All Hands on Deck: We Need Multiple Approaches To Uncover the Neuroscience behind the Opioid Overdose Crisis	36
Lateral Habenula and Its Potential Roles in Pain and Related Behaviors	35
Ferroptosis, Pyroptosis, and Cuproptosis in Alzheimer’s Disease	34
Impaired Dopamine Release and Latent Learning in Alzheimer’s Disease Model Zebrafish	34
Unraveling the Interplay of Dopamine, Carbon Monoxide, and Heme Oxygenase in Neuromodulation and Cognition	32
miR-29a/b1 Regulates BACE1 in Aluminum-Induced Aβ Deposition in Vitro	32
Chrysin-Loaded Chitosan Nanoparticle-Mediated Neuroprotection in Aβ_1–42-Induced Neurodegenerative Conditions in Zebrafish	32
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Restricts Inflammatory Progression through Limiting Macrophage Infiltration in DRG and Sciatic Nerve during Diabetic Peripheral Neuropathy	32
The Orphan Receptor GPR151: Discovery, Expression, and Emerging Biological Significance	32
Issue Editorial Masthead	31
Issue Publication Information	31
Issue Editorial Masthead	31
Baihe Extracts Reduce the Activation and Apoptosis of Microglia in the Hippocampus of Mice with Depression-like Behaviors by Downregulating MYC	31
Synthesis, Pharmacological Characterization, and Binding Mode Analysis of 8-Hydroxy-Tetrahydroisoquinolines as 5-HT₇ Receptor Inverse Agonists	31
Issue Editorial Masthead	30
Issue Publication Information	30
Phytic Acid Maintains Peripheral Neuron Integrity and Enhances Survivability against Platinum-Induced Degeneration via Reducing Reactive Oxygen Species and Enhancing Mitochondrial Membrane Potential	30
Issue Editorial Masthead	30
Cytotoxicity of Amyloid β1–42 Fibrils to Brain Immune Cells	30
Ketogenic Diet for Neonatal Hypoxic–Ischemic Encephalopathy	29
Artificial Neural Networks Coupled with MALDI-TOF MS Serum Fingerprinting To Classify and Diagnose Pathological Pain Subtypes in Preclinical Models	29
Neuroprotective Effects of σ₂R/TMEM97 Receptor Modulators in the Neuronal Model of Huntington’s Disease	29
Dysregulated Neurotransmission and the Role of Viruses in Alzheimer’s Disease	29
Development of a Dihydroquinoline–Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor	29
Novel Small-Molecule Inhibitor of NLRP3 Inflammasome Reverses Cognitive Impairment in an Alzheimer’s Disease Model	29
Luminescent PLGA Nanoparticles for Delivery of Darunavir to the Brain and Inhibition of Matrix Metalloproteinase-9, a Relevant Therapeutic Target of HIV-Associated Neurological Disorders	29
Aspartic Acid-Modified Phospholipids Regulate Cell Response and Rescue Memory Deficits in APP/PS1 Transgenic Mice	28
Age-Related Neurometabolomic Signature of Mouse Brain	28
Rapid Generation of Neurospheres from Hippocampal Neurons Using Extracellular-Matrix-Mimetic Scaffolds	27
Transthyretin Binding Mode Dichotomy of Fluorescent trans-Stilbene Ligands	27
3D Super-Resolution Imaging of PSD95 Reveals an Abundance of Diffuse Protein Supercomplexes in the Mouse Brain	26
Multifarious Targets and Recent Developments in the Therapeutics for the Management of Bone Cancer Pain	26
Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues	26
Issue Editorial Masthead	26
Citric Acid-Derived Carbon Quantum Dots Attenuate Paraquat-Induced Neuronal Compromise In Vitro and In Vivo	26
Myricetin Restores Aβ-Induced Mitochondrial Impairments in N2a-SW Cells	26
Reactivity of Olanzapine and Tricyclic Antidepressants on the Protective Effects of Trolox on Lipid Peroxidation Evaluated Using Fluorescence Anisotropy, Electron Paramagnetic Resonance Spectrometry,	26
Damage of the Phospholipid Bilayer by Aβ42 at Physiologically Relevant Peptide Concentrations	25
Neuroprotective Effects of an N-Salicyloyl Tryptamine Derivative against Cerebral Ischemia/Reperfusion Injury	25
Hyperphosphorylation-Mimetic TDP-43 Drives Amyloid Formation and Possesses Neuronal Toxicity at the Oligomeric Stage	25

Role of Necroptosis in Central Nervous System Diseases	25
The Mineralocorticoid Receptor: An Emerging Pharmacotherapeutic Target for Alcohol Use Disorder?	25
Defects in Mouse Cortical Glutamate Uptake Can Be Unveiled In Vivo by a Two-in-One Quantitative Microdialysis	25
α₁ Proline 277 Residues Regulate GABA_AR Gating through M2-M3 Loop Interaction in the Interface Region	25
Methylmalonic Acid Compromises Respiration and Reduces the Expression of Differentiation Markers of SH-SY5Y Human Neuroblastoma Cells	25
A Synthetically Accessible Small-Molecule Inhibitor of USP5-Cav3.2 Calcium Channel Interactions with Analgesic Properties	24
Chalcone Analogue as New Candidate for Selective Detection of α-Synuclein Pathology	24
5-HT₃ Receptor MX Helix Contributes to Receptor Function	23
MiR-23b-3p Improves Brain Damage after Status Epilepticus by Reducing the Formation of Pathological High-Frequency Oscillations via Inhibition of cx43 in Rat Hippocampus	23
Targeting Oxidative Stress in Neurodegenerative Disorders: A Novel Role for PCSK9 Inhibition?	23
Farnesylation of Zebrafish G-Protein-Coupled Receptor Kinase Using Bio-orthogonal Labeling	23
Dopamine Release Impairments Accompany Movement Vigor Deficiency in an Exercise-Induced Fatigue Mouse Model	23
Subchronic Acrylamide Exposure Activates PERK-eIF2α Signaling Pathway and Induces Synaptic Impairment in Rat Hippocampus	23
Covalent Fragment Inhibits RhoA Activation by Guanine Exchange Factors	23
Preclinical Evaluation of [¹¹C]YC-72-AB85 for In Vivo Visualization of Heat Shock Protein 90 in Brain and Cancer with Positron Emission Tomography	22
Distinct Cholesterol Localization in Glioblastoma Multiforme Revealed by Mass Spectrometry Imaging	22
Characterization of the Novel P2X7 Receptor Radioligand [³H]JNJ-64413739 in Human Brain Tissue	22
Prenatal Sevoflurane Exposure Impairs the Learning and Memory of Rat Offspring via HMGB1-Induced NLRP3/ASC Inflammasome Activation	22
Sequence-Dependent Conformational Properties of PGGG Motif in Tau Repeats: Insights from Molecular Dynamics Simulations of Narrow Pick Filament	22
TRIOL Inhibits Rapid Intracellular Acidification and Cerebral Ischemic Injury: The Role of Glutamate in Neuronal Metabolic Reprogramming	22
Taylor Dispersion Analysis and Atomic Force Microscopy Provide a Quantitative Insight into the Aggregation Kinetics of Aβ (1–40)/Aβ (1–42) Amyloid Peptide Mixtures	22
Neuropathological Effects of Chemotherapeutic Drugs	21
Empirical Analysis of Drug Targets for Nervous System Disorders	21
A Small Molecule Stabilizes the Disordered Native State of the Alzheimer’s Aβ Peptide	21
New Blood–Brain Barrier Models Using Primary Parkinson’s Disease Rat Brain Endothelial Cells and Astrocytes for the Development of Central Nervous System Drug Delivery Systems	21
Divergent Age-Dependent Conformational Rearrangement within Aβ Amyloid Deposits in APP23, APPPS1, and App^NL-F Mice	21
Bcl-2-Homology-Only Proapoptotic Peptides Modulate β-Amyloid Aggregation and Toxicity	21
On the Tracks of the Aggregation Mechanism of the PHF6 Peptide from Tau Protein: Molecular Dynamics, Energy, and Interaction Network Investigations	21
Ascaris suum Informs Extrasynaptic Volume Transmission in Nematodes	21
An S-Shaped Aβ42 Cross-β Hexamer Embedded into a Lipid Bilayer Reveals Membrane Disruption and Permeability	20
Issue Publication Information	20
Classics in Chemical Neuroscience: Tianeptine	20
Chemical Perspective of the Mechanism of Action of Antiamyloidogenic Compounds Using a Minimalistic Peptide as a Reductionist Model	20
Issue Editorial Masthead	20
Cells Overexpressing ALS-Associated SOD1 Variants Are Differentially Susceptible to CuATSM-Associated Toxicity	20
Monitoring Molecules in Neuroscience	20
Strategic Design of Amyloid-β Species Fluorescent Probes for Alzheimer’s Disease	20
Ratiometric Fluorescent Probe Promotes Trans-differentiation of Human Mesenchymal Stem Cells to Neurons	19
Specific Phospholipid Modulation by Muscarinic Signaling in a Rat Lesion Model of Alzheimer’s Disease	19
Glial Cells and Itch: Possible Targets for Novel Antipruritic Therapies	19
Automated, Transferable, and Ethanol-Free Radiosynthesis of [¹¹C]Butanol	19
Identifying an Optimal Neuroinflammation Treatment Using a Nanoligomer Discovery Engine	19
Prussian Blue Nanozyme Treatment of Ischemic Brain Injury via Reducing Oxidative Stress Inhibits Inflammation, Suppresses Apoptosis, and Promotes Neurological Recovery	19
Cardiac Sympathetic Positron Emission Tomography Imaging with Meta-[¹⁸F]Fluorobenzylguanidine is Sensitive to Uptake-1 in Rats	19
Lipopolysaccharide Effects on Neurotransmission: Understanding Implications for Depression	19
Effect of Cannabidiol on the Neural Glyoxalase Pathway Function and Longevity of Several C. elegans Strains Including a C. elegans Alzheimer’s Disease Model	19
Design and Development of Benzothiazole-Based Fluorescent Probes for Selective Detection of Aβ Aggregates in Alzheimer’s Disease	18
Issue Editorial Masthead	18
Issue Publication Information	18
Issue Publication Information	18
Modulation of α-Synuclein Fibrillation and Toxicity by 4-Phenylbutyric Acid	18
Polyglutamine (PolyQ) Diseases: Navigating the Landscape of Neurodegeneration	18
Neuroprotective Effect of Withaferin Derivatives toward MPP⁺ and 6-OHDA Toxicity to Dopaminergic Neurons	18
Issue Publication Information	18
Issue Editorial Masthead	18
Small-Molecule Cdc25A Inhibitors Protect Neuronal Cells from Death Evoked by NGF Deprivation and 6-Hydroxydopamine	18
Polyaniline-Conjugated Boron Nitride Nanoparticles Exhibiting Potent Effects against Pathogenic Brain-Eating Amoebae	18
Issue Editorial Masthead	18
Issue Editorial Masthead	18
Issue Editorial Masthead	17
Edge Substitution Effects of Histidine Tautomerization Behaviors on the Structural Properties and Aggregation Properties of Aβ(1–42) Mature Fibril	17
Dopaminergic Modulation and Computational ADMET Insights for the Antidepressant-like Effect of N-(3-(Phenylselanyl)prop-2-yn-1-yl)benzamide	17
Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Adenosine in the Control of Behavioral and Electrophysiological Modifications Caused by Chronic Stress	17
Determination of Trends Underlying Aspartic Acid Isomerization in Intact Proteins Reveals Unusually Rapid Isomerization of Tau	17
Issue Editorial Masthead	17
Kinesin Nanomotors Mediated Trafficking of NMDA-Loaded Cargo as A Novel Target in Chronic Pain	17
Doubly Constrained C-terminal of Roc (COR) Domain-Derived Peptides Inhibit Leucine-Rich Repeat Kinase 2 (LRRK2) Dimerization	17
Deciphering the Role of Fluctuation Dependent Intercellular Communication in Neural Stem Cell Development	17
Single-Molecule Fingerprinting Reveals Different Growth Mechanisms in Seed Amplification Assays for Different Polymorphs of α-Synuclein Fibrils	17
Guanidine Derivative ADS1017, a Potent Histamine H₃ Receptor Antagonist with Promising Analgesic Activity and Satisfactory Safety Profile	17
Issue Editorial Masthead	17
Evaluation of Alpha-Synuclein and Tau Antiaggregation Activity of Urea and Thiourea-Based Small Molecules for Neurodegenerative Disease Therapeutics	17
Benzo[d]imidazole-pyrrolo[1,2-a]pyrazine Hybrids Ameliorate Amyloid Aggregates in the Brain of Alzheimer Transgenic Mice	17
Deciphering the Inhibitory Mechanism of Naphthoquinone–Dopamine on the Aggregation of Tau Core Fragments PHF6* and PHF6	17
Saroglitazar Enhances Memory Functions and Adult Neurogenesis via Up-Regulation of Wnt/β Catenin Signaling in the Rat Model of Dementia	17
Identification of a Novel Allosteric Site at the M₅Muscarinic Acetylcholine Receptor	17
Study of the Neurotransmitter Changes Adjusted by Circadian Rhythm in Depression Based on Liver Transcriptomics and Correlation Analysis	17
Proteome Aggregation in Cells Derived from Amyotrophic Lateral Sclerosis Patients for Personalized Drug Evaluation	17
Synthesis and Preclinical Evaluation of 22-[¹⁸F]Fluorodocosahexaenoic Acid as a Positron Emission Tomography Probe for Monitoring Brain Docosahexaenoic Acid Uptake Kinetics	17
Issue Publication Information	17

Calycosin Inhibit PANoptosis and Alleviate Brain Damage: A Bioinformatics and Experimental Verification Approach	17
Short-Term Administration of Common Anesthetics Does Not Dramatically Change the Endogenous Peptide Profile in the Rat Pituitary	17
DARK Classics in Chemical Neuroscience: Loperamide	16
Regulation of Dopamine Release by Tonic Activity Patterns in the Striatal Brain Slice	16
Melatonin Relieves Paclitaxel-Induced Neuropathic Pain by Regulating pNEK2-Dependent Epigenetic Pathways in DRG Neurons	16
Osmoregulatory Role of Betaine and Betaine/γ-Aminobutyric Acid Transporter 1 in Post-Traumatic Syringomyelia	16
Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model	16
Discovery of Resorcinol-Based Polycyclic Structures as Tyrosinase Inhibitors for Treatment of Parkinson’s Disease	16
Brain Targeting and Aβ Binding Bifunctional Nanoparticles Inhibit Amyloid Protein Aggregation in APP/PS1 Transgenic Mice	16
Hemispheric Utilization of Alpha Oscillatory Dynamics as a Unique Biomarker of Neural Compensation in Females with Fragile X Syndrome	16
Shared and Unique Disease Pathways in Amyotrophic Lateral Sclerosis and Parkinson’s Disease Unveiled in Peripheral Blood Mononuclear Cells	16
Understanding the Inhibitory and Antioxidant Effects of Pyrroloquinoline Quinone (PQQ) on Copper(II)-Induced α-Synuclein-119 Aggregation	16
Linking the Triad of Telomere Length, Inflammation, and Gut Dysbiosis in the Manifestation of Depression	16
Neurotrophic Activity and Its Modulation by Zinc Ion of a Dimeric Peptide Mimicking the Brain-Derived Neurotrophic Factor N-Terminal Region	16
Underlying Causes and Treatment Modalities for Neurological Deficits in COVID-19 and Long-COVID	16
Issue Publication Information	16
¹H NMR Metabolomics and Lipidomics To Monitor Positive Responses in Children with Autism Spectrum Disorder Following a Guided Parental Intervention: A Pilot Study	15
The Interplay between MiR-134/BDNF and LKB1/AMPK/SIRT1 Accentuates the Antidepressant Efficacy of Empagliflozin in Ovariectomized Rats	15
NNL-3: A Synthetic Intermediate or a New Class of Hydroxybenzotriazole Esters with Cannabinoid Receptor Activity?	15
Correction to “Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor”	15
Determining Structural Changes for Ligand Recognition between Human and Rat Phosphorylated BACE1 in Silico and Its Phosphorylation by GSK3β at Thr252 by in Vitro Studies	15
Red-Light-Photosensitized Tyrosine 10 Nitration of β-Amyloid_1–42 Diverts the Protein from Forming Toxic Aggregates	15
In Vitro and In Vivo Investigations of Chromone Derivatives as Potential Multitarget-Directed Ligands: Cognitive Amelioration Utilizing a Scopolamine-Induced Zebrafish Model	15
Fustin Inhibits Oxidative Free Radicals and Inflammatory Cytokines in Cerebral Cortex and Hippocampus and Protects Cognitive Impairment in Streptozotocin-Induced Diabetic Rats	15
Role of Imaging Modalities and N-Acetylcysteine Treatment in Sepsis-Associated Encephalopathy	15
Kappa Opioid Receptor Activation Induces Epigenetic Silencing of Brain-Derived Neurotropic Factor via HDAC5 in Depression	15
Serotonin 1A Receptors Modulate Serotonin 2A Receptor-Mediated Behavioral Effects of 5-Methoxy-N,N-dimethyltryptamine Analogs in Mice	15
Synthesis and Preclinical Evaluation of Fluorinated 5-Azaindoles as CB2 PET Radioligands	15
Family of Structurally Related Bioconjugates Yields Antibodies with Differential Selectivity against Ketamine and 6-Hydroxynorketamine	15
Monitoring Fast Synaptic Transmission of Neuromodulatory Transmitters To Define Drug Effects in the Brain	15
New Alpha9 nAChR Ligands Based on a 5-(Quinuclidin-3-ylmethyl)-1,2,4-oxadiazole Scaffold	15
Exploring the Therapeutic Potential of Benfotiamine in a Sporadic Alzheimer’s-Like Disease Rat Model: Insights into Insulin Signaling and Cognitive function	15
TMEM106B Fibrils from FTLD Patients and Healthy Controls	15
Bicuculline and Bumetanide Attenuate Sevoflurane-Induced Impairment of Myelination and Cognition in Young Mice	15
Understanding Neuropeptide Transmission in the Brain by Optical Uncaging and Release	15
Substrate Selection Criteria in Regulated Intramembrane Proteolysis	14
Bidirectional Responses of Eight Neuroinflammation-Related Transcriptional Factors to 64 Flavonoids in Astrocytes with Transposable Insulated Signaling Pathway Reporters	14
Hypoxic Preconditioning Modulates BDNF and Its Signaling through DNA Methylation to Promote Learning and Memory in Mice	14
Cooperativity of α-Synuclein Binding to Lipid Membranes	14
New Insights on Protein Folding and Misfolding: Histidine Behaviors	14
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease	14
Microscopic Characterization of the Chloride Permeation Pathway in the Human Excitatory Amino Acid Transporter 1 (EAAT1)	14
A Transcription Factor ZNF384, Regulated by LINC00265, Activates the Expression of IFI30 to Stimulate Malignant Progression in Glioma	14
Issue Editorial Masthead	14
Issue Editorial Masthead	14
Evolving Role of Natural Products from Traditional Medicinal Herbs in the Treatment of Alzheimer’s Disease	14
Potential of ADAM 17 Signal Peptide To Form Amyloid Aggregates in Vitro	14
Pharmacological Mechanism of the Non-hallucinogenic 5-HT_2A Agonist Ariadne and Analogs	14
Observation of α-Synuclein Preformed Fibrils Interacting with SH-SY5Y Neuroblastoma Cell Membranes Using Scanning Ion Conductance Microscopy	14
Design, Synthesis, and Pharmacological Evaluation of N-Propargylated Diphenylpyrimidines as Multitarget Directed Ligands for the Treatment of Alzheimer’s Disease	14
Optical Precise Ablation of Targeted Individual Neurons In Vivo	14
Dynamic and Rapid Detection of Guanosine during Ischemia	14
Issue Publication Information	14
Repurposing of the PET Probe Prototype PiB for Label and Radiation-Free CEST MRI Molecular Imaging of Amyloid	14
DARK Classics in Chemical Neuroscience: Bucinnazine	14
Synchrotron X-ray Fluorescence and FTIR Signatures for Amyloid Fibrillary and Nonfibrillary Plaques	14
Dysregulation of Neuropeptide and Tau Peptide Signatures in Human Alzheimer’s Disease Brain	14
Molecular Insights into the Dynamics of Amyloid Fibril Growth: Elongation and Lateral Assembly of GNNQQNY Protofibrils	14
In Vitro and In Silico Analysis of the Residence Time of Serotonin 5-HT₇ Receptor Ligands with Arylpiperazine Structure: A Structure–Kinetics Relationship Study	14
Unraveling the Connection of Epstein–Barr Virus and Its Glycoprotein M_146–157 Peptide with Neurological Ailments	14
Issue Editorial Masthead	14
Effects of Anesthetic Administration on Rat Hypothalamus and Cerebral Cortex Peptidome	13
Issue Editorial Masthead	13
Psychedelic-like Activity of Norpsilocin Analogues	13
Atomic Force Microscopy Applied to the Study of Tauopathies	13
4-Amino-3′,4′-dihydroxychalcone Increases Tau Dynamics in Phase-Separated Droplets and Inhibits Tau Aggregation	13
Short-Term Extremely Low-Frequency Electromagnetic Field Inhibits Synaptic Plasticity of Schaffer Collateral-CA1 Synapses in Rat Hippocampus via the Ca²⁺/Calcineurin Pathway	13
Neuralized1-Mediated CPEB3 Ubiquitination in the Spinal Dorsal Horn Contributes to the Pathogenesis of Neuropathic Pain in Rats	13
Differential Effects of Nicotine, Alcohol, and Coexposure on Neuroimmune-Related Protein and Gene Expression in Corticolimbic Brain Regions of Rats	13
Compensatory Contextual Fear Memory Pathways Develop in the Infralimbic Cortex within 3 Days after the First Test in the Absence of the Dorsal Hippocampus	13
Haloperidol Prevents Oxytosis/Ferroptosis by Targeting Lysosomal Ferrous Ions in a Manner Independent of Dopamine D2 and Sigma-1 Receptors	13
Formation of Calprotectin Inhibits Amyloid Aggregation of S100A8 and S100A9 Proteins	13
Downregulation of Sp1 Inhibits the Expression of HDAC1/SOX10 to Alleviate Neuropathic Pain-like Behaviors after Spinal Nerve Ligation in Mice	13
Tomographic Imaging and Correlation to Quantify Vascular and Inflammatory Changes in an Experimental Spinal Cord Injury	13
Impact of Indole Inclusion in the Design of Multi-Tactical Metal-Binding Tetra-Aza Macrocycles that Target the Molecular Features of Neurodegeneration	13
Glycation Produces Topologically Different α-Synuclein Oligomeric Strains and Modulates Microglia Response via the NLRP3-Inflammasome Pathway	13
Ferroptosis Regulated by 5-HT3a Receptor via Calcium/Calmodulin Signaling Contributes to Neuropathic Pain in Brachial Plexus Avulsion Rat Models	13
Probing Chemical Complexity of Amyloid Plaques in Alzheimer’s Disease Mice using Hyperspectral Raman Imaging	13
Activation Pathways of Neurotensin Receptor 1 Elucidated Using Statistical Machine Learning	13
Myricetin: A Potent Anti-Amyloidogenic Polyphenol against Superoxide Dismutase 1 Aggregation	13
Biophysical Characterization and Preformulation Studies of Human Mesencephalic Astrocyte-Derived Neurotropic Factor	13
Comprehensive Characterization of a Systematic Library of Alkyl and Alicyclic Synthetic Cannabinoids Related to CUMYL-PICA, CUMYL-BUTICA, CUMYL-CBMICA, and CUMYL-PINACA	13
Multivalent Gd-DOTA Decorated Oligopeptide as Sensitive MRI Molecular Probes for In Vivo Imaging of Brain Connectivity	13
Comparing Brain and Blood Lipidome Changes following Single and Repetitive Mild Traumatic Brain Injury in Rats	13
Characterization of (R)- and (S)-[¹⁸F]OF-NB1 in Rodents as Positron Emission Tomography Probes for Imaging GluN2B Subunit-Containing N-Methyl-d-Aspartate Rec	13
Functional Characterization of an Arylsulfonamide-Based Small-Molecule Inhibitor of the NLRP3 Inflammasome	13
Evaluating the Neuroprotective Potential of Novel Benzodioxole Derivatives in Parkinson’s Disease via AMPA Receptor Modulation	12
4-Acyl-3,4-dihydropyrrolo[1,2-a]pyrazine Derivative Rescued the Hippocampal-Dependent Cognitive Decline of 5XFAD Transgenic Mice by Dissociating Soluble and Insoluble Aβ Aggregates	12
Lipidomics Reveals Dysregulated Glycerophospholipid Metabolism in the Corpus Striatum of Mice Treated with Cefepime	12
De Novo Design of a β-Helix Tau Protein Scaffold: An Oligomer-Selective Vaccine Immunogen Candidate for Alzheimer’s Disease	12
Visualization of Unconjugated Bilirubin In Vivo with a Novel Approach Using Chemical Exchange Saturation Transfer Magnetic Resonance Imaging in a Rat Model	12
Role of Hydrophobicity at the N-Terminal Region of Aβ42 in Secondary Nucleation	12
Patent Review of Novel Biologics Targeting Opioid Use Disorder (2018–2024)	12
Dexamethasone-Enhanced Continuous Online Microdialysis for Neuromonitoring of O₂ after Brain Injury	12
The Pharmacological Activity of Garlic (Allium sativum) in Parkinson’s Disease: From Molecular Mechanisms to the Therapeutic Potential	12