OOIR: Observatory of International Research

Papers

(The median citation count of ACS Chemical Neuroscience is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Neurochemical and Morphological Comparisons of Motor Nerve Organoids and Spinal-Cord Explants	218
Synthesis and Evaluation of Benzylic ¹⁸F-Labeled N-Biphenylalkynyl Nipecotic Acid Derivatives for PET Imaging of GABA Transporter 1	183
Correction to “Pharmacological Characterizations of anti-Dementia Memantine Nitrate via Neuroprotection and Vasodilation in Vitro and in Vivo”	158
Issue Publication Information	121
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Heteroaggregation of Wild-Type and ALS Mutant SOD1	66
Silymarin-Based Nanosheets Efficiently Protect Mitochondria against Oxidative Damage Mediated by α-Synuclein Amyloid Aggregates	66
Enhanced Analgesic Efficacy and Reduced Side Effects of Morphine by Combination with PD-1 Agonist	59
Distinct m ⁶ A and m ¹ A Responses to Neuronal Depolarization in Cortical Neurons	58
Rational Design, Synthesis, and Evaluation of Rofecoxib-Based Photosensitizers for the NIR Imaging and Photo-Oxidization of Aβ Aggregates	56
Caffeine and Nicotine with N-Substituted Diazirine Photoaffinity Labels Form Adducts at Tyrosine-39 of α-Synuclein	51
Pathological Mutations D169G and P112H Electrostatically Aggravate the Amyloidogenicity of the Functional Domain of TDP-43	48
New Multitarget Molecules Derived from Caffeine as Potentiators of the Cholinergic System	48
Synthesis and Neuroprotective Evaluation of Substituted Indanone/Benzofuranone and Piperidine Hybrids	46
All Hands on Deck: We Need Multiple Approaches To Uncover the Neuroscience behind the Opioid Overdose Crisis	45
Role of Bmal1 and Gut Microbiota in Alzheimer’s Disease and Parkinson’s Disease Pathophysiology: The Probable Effect of Melatonin on Their Association	45
Emerging Frontiers in Conformational Exploration of Disordered Proteins: Integrating Autoencoder and Molecular Simulations	44
FPT, a 2-Aminotetralin, Is a Potent Serotonin 5-HT_1A, 5-HT_1B, and 5-HT_1D Receptor Agonist That Modulates Cortical Electroencephalogram Activity in Adult Fmr1 Kn	42
Assessing the Multitarget Therapeutic Potential of Novel 9-Aminoacridine Derivatives for Alzheimer’s Disease	41
JNK3 Overexpression in the Entorhinal Cortex Impacts on the Hippocampus and Induces Cognitive Deficiencies and Tau Misfolding	40
Chrysin-Loaded Chitosan Nanoparticle-Mediated Neuroprotection in Aβ_1–42-Induced Neurodegenerative Conditions in Zebrafish	38

Furanoditerpenes from Spongia (Spongia) tubulifera Display Mitochondrial-Mediated Neuroprotective Effects by Targeting Cyclophilin D	38
Phosphoproteomic Analysis of Cortical Tissue from Mice Lacking Both CaMKIIα and CaMKIIβ Identifies Novel In Vivo Substrates	38
Repurposing Anakinra for Alzheimer’s Disease: The In Vitro and In Vivo Effects of Anakinra on LPS- and AC-Induced Neuroinflammation	37
Altered Composition of Ceramides and Sphingomyelin Distinctly Modulates the Organizational Landscape and Microdomain Dynamics of Neuronal Plasma Membrane: A Computational Microscopy of Alzheimer’s Bra	37
Rimota-Gd: Paramagnetic Probe for In Vivo MRI Studies of the Cannabinoid 1 Receptor Distribution in the Mouse Brain	37
Exploring the Application Potential of α-Synuclein Molecular Probes in Early Diagnosis of Parkinson’s Disease: Focus on Imaging Methods	36
Microinvasive Probes for Monitoring Electrical and Chemical Neural Activity in Nonhuman Primates	36
Dl-3-n-Butylphthalide Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion: Associations with Mitochondrial Permeability Transition Pore Closure and Suppression of Excessive Mitoph	36
Discrimination between Alpha-Synuclein Protein Variants with a Single Nanometer-Scale Pore	35
Disease-Associated Mutations in Tau Encode for Changes in Aggregate Structure Conformation	35
Study on the Difference of Protective Efficacy and Mechanism of Radix Aconiti Coreani and Rhizoma Typhonii in Gerbils with Ischemic Stroke	34
The Orphan Receptor GPR151: Discovery, Expression, and Emerging Biological Significance	34
Competitive Antagonism of Xylazine on α7 Nicotinic Acetylcholine Receptors and Reversal by Curcuminoids	33
Unraveling the Interplay of Dopamine, Carbon Monoxide, and Heme Oxygenase in Neuromodulation and Cognition	33
Targeting Microglial Immunoproteasome: A Novel Approach in Neuroinflammatory-Related Disorders	33
Impaired Dopamine Release and Latent Learning in Alzheimer’s Disease Model Zebrafish	31
Caffeic Acid Ameliorates l -Methionine-Induced Hyperhomocysteinemia, Leading to Decreased Adult Neurogenesis and Oxidative Stress Status in Adult Rat	31
Ferroptosis, Pyroptosis, and Cuproptosis in Alzheimer’s Disease	31
Male-Dominant Effects of Chd8 Haploinsufficiency on Synaptic Phenotypes during Development in Mouse Prefrontal Cortex	31
Issue Publication Information	29
Synthesis, Pharmacological Characterization, and Binding Mode Analysis of 8-Hydroxy-Tetrahydroisoquinolines as 5-HT₇ Receptor Inverse Agonists	29
Role of NLRP3 Inflammasome in Post-Spinal-Cord-Injury Anxiety and Depression: Molecular Mechanisms and Therapeutic Implications	29
Issue Editorial Masthead	28
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Tricyclic Antidepressants as Prospective α-Synucleinopathy Fighters: Evidence of Protein Binding and Antiaggregation Activity	27
Development of a Dihydroquinoline–Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor	27
3D Super-Resolution Imaging of PSD95 Reveals an Abundance of Diffuse Protein Supercomplexes in the Mouse Brain	27
Issue Editorial Masthead	27
5-HT₃ Receptor MX Helix Contributes to Receptor Function	27
Aspartic Acid-Modified Phospholipids Regulate Cell Response and Rescue Memory Deficits in APP/PS1 Transgenic Mice	27
Neuroprotective Effects of σ ₂ R/TMEM97 Receptor Modulators in the Neuronal Model of Huntington’s Disease	27
Rational Design and Evaluation of Rivastigmine-Based Pleiotropic Prodrugs for the Treatment of Alzheimer’s Disease	26
Cytotoxicity of Amyloid β1–42 Fibrils to Brain Immune Cells	26
Vitamin D Ameliorates Doxorubicin-Induced Cognitive Dysfunction via Modulation of the SFRP1/β-Catenin Axis	26
Decoding the Relationship between Alzheimer’s Disease and Type-2 Diabetes via the Protein Aggregation Prism	26
Neuroprotective Effects of an N-Salicyloyl Tryptamine Derivative against Cerebral Ischemia/Reperfusion Injury	25
Reactivity of Olanzapine and Tricyclic Antidepressants on the Protective Effects of Trolox on Lipid Peroxidation Evaluated Using Fluorescence Anisotropy, Electron Paramagnetic Resonance Spectrometry,	25
Exploring the Therapeutic Potential of Ar-tur in Alzheimer Disease: A Cheminformatics, Pharmacokinetics, and System Pharmacology Approach	25
Phytic Acid Maintains Peripheral Neuron Integrity and Enhances Survivability against Platinum-Induced Degeneration via Reducing Reactive Oxygen Species and Enhancing Mitochondrial Membrane Potential	25
R -MDDMA is a Safer Analogue of MDMA with Therapeutic Potential	25
Sex-Dependent Behavioral and Biochemical Alterations in a Prenatal Oral Valproic Acid Rat Model of Autism	25
Ketogenic Diet for Neonatal Hypoxic–Ischemic Encephalopathy	25
Progress toward Multianalyte Neurochemical Detection: Techniques and Applications	25
Prenatal Sevoflurane Exposure Impairs the Learning and Memory of Rat Offspring via HMGB1-Induced NLRP3/ASC Inflammasome Activation	24
Covalent Fragment Inhibits RhoA Activation by Guanine Exchange Factors	24
Hyperphosphorylation-Mimetic TDP-43 Drives Amyloid Formation and Possesses Neuronal Toxicity at the Oligomeric Stage	24
The Mineralocorticoid Receptor: An Emerging Pharmacotherapeutic Target for Alcohol Use Disorder?	24

Identification of Novel Triazole–Pyrazole Conjugates as Potential Anticonvulsant Agents: Synthesis and Biological Evaluations	24
Dysregulated Neurotransmission and the Role of Viruses in Alzheimer’s Disease	24
MiR-23b-3p Improves Brain Damage after Status Epilepticus by Reducing the Formation of Pathological High-Frequency Oscillations via Inhibition of cx43 in Rat Hippocampus	24
Artificial Neural Networks Coupled with MALDI-TOF MS Serum Fingerprinting To Classify and Diagnose Pathological Pain Subtypes in Preclinical Models	24
α₁ Proline 277 Residues Regulate GABA_AR Gating through M2-M3 Loop Interaction in the Interface Region	23
Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D₂ Receptor	23
Issue Editorial Masthead	23
Targeting Oxidative Stress in Neurodegenerative Disorders: A Novel Role for PCSK9 Inhibition?	23
Dopamine Release Impairments Accompany Movement Vigor Deficiency in an Exercise-Induced Fatigue Mouse Model	23
Distinct Cholesterol Localization in Glioblastoma Multiforme Revealed by Mass Spectrometry Imaging	23
Specificity and Promiscuity of Phosphoinositide Lipid Interactions with the Serotonin _1A Receptor: Insights from Submillisecond Coarse-Grain Simulati	23
Transferrin-Functionalized Chitosan Nanoparticles Enable Intranasal Brain Delivery of Cariprazine with Enhanced Neuropharmacological Efficacy	23
Sequence-Dependent Conformational Properties of PGGG Motif in Tau Repeats: Insights from Molecular Dynamics Simulations of Narrow Pick Filament	23
Damage of the Phospholipid Bilayer by Aβ42 at Physiologically Relevant Peptide Concentrations	22
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Issue Editorial Masthead	22
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Transthyretin Binding Mode Dichotomy of Fluorescent trans-Stilbene Ligands	22
The Synergistic Potential of Rationally Designed Phenol-Triazole Derivatives to Attenuate Aβ/Cu²⁺–Aβ Aggregation and Reactive Oxygen Species	22
Issue Publication Information	22
Role of Necroptosis in Central Nervous System Diseases	22
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Restricts Inflammatory Progression through Limiting Macrophage Infiltration in DRG and Sciatic Nerve during Diabetic Peripheral Neuropathy	22
Citric Acid-Derived Carbon Quantum Dots Attenuate Paraquat-Induced Neuronal Compromise In Vitro and In Vivo	22
TRIOL Inhibits Rapid Intracellular Acidification and Cerebral Ischemic Injury: The Role of Glutamate in Neuronal Metabolic Reprogramming	22
Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues	22
Issue Publication Information	22
Deciphering the Inhibitory Mechanism of ALS-Associated N352S and S352p Variants against TDP-43 Aggregation and Its Destabilization Effect on TDP-43 Protofibrils	21
Deep Proteome Profiling of Rat Dorsal Striatal Synaptoneurosomes Following Methamphetamine Exposure	21
Monitoring Molecules in Neuroscience	21
Neuroprotective Effect of Withaferin Derivatives toward MPP⁺ and 6-OHDA Toxicity to Dopaminergic Neurons	21
Identifying an Optimal Neuroinflammation Treatment Using a Nanoligomer Discovery Engine	21
Modulation of α-Synuclein Fibrillation and Toxicity by 4-Phenylbutyric Acid	21
Glial Cells and Itch: Possible Targets for Novel Antipruritic Therapies	20
Design and Development of Benzothiazole-Based Fluorescent Probes for Selective Detection of Aβ Aggregates in Alzheimer’s Disease	20
An S-Shaped Aβ42 Cross-β Hexamer Embedded into a Lipid Bilayer Reveals Membrane Disruption and Permeability	20
N -Benzyl-tryptamine Derivatives as Serotonin 5-HT _2A Receptor (5-HT _2A	20
On the Tracks of the Aggregation Mechanism of the PHF6 Peptide from Tau Protein: Molecular Dynamics, Energy, and Interaction Network Investigations	20
Hydrogen Sulfide–Releasing Insulin Polypeptide Mitigates Hyperglycemia-Induced Neurotoxicity and Cognitive Deficits In Vivo	20
Effects of Ethanol and Opioid Receptor Antagonists Naltrexone and LY2444296 on the Organization of Cholesterol- and Sphingomyelin-Enriched Plasma Membrane Domains	19
Automated, Transferable, and Ethanol-Free Radiosynthesis of [¹¹C]Butanol	19
Characterization of the Novel P2X7 Receptor Radioligand [³H]JNJ-64413739 in Human Brain Tissue	19
Combination of Resveratrol and Curcumin with Anti-Amyloid Monoclonal Antibodies Aducanumab and Lecanemab Leads to Greater Inhibition of Amyloid-Beta Aggregation	19
Ratiometric Fluorescent Probe Promotes Trans-differentiation of Human Mesenchymal Stem Cells to Neurons	19
Divergent Age-Dependent Conformational Rearrangement within Aβ Amyloid Deposits in APP23, APPPS1, and App ^NL-F	19
In Vivo Characterization of Synthetic Cannabidiol Analogs for Seizure Suppression in Zebrafish	19
Small-Molecule Cdc25A Inhibitors Protect Neuronal Cells from Death Evoked by NGF Deprivation and 6-Hydroxydopamine	19
The Aromatherapeutic Effects of Herbal Compounds in Inhibiting Metal-Induced Structural Changes in Tau Protein Fibrillar Aggregates	19
Polyglutamine (PolyQ) Diseases: Navigating the Landscape of Neurodegeneration	19
Synthesis, Labeling, and Biological Evaluation of P2Y₁₂ Receptor Radioligands for Positron Emission Tomography Imaging of Neuroinflammation	19
Issue Publication Information	18
Synthesis and Preclinical Evaluation of 22-[¹⁸F]Fluorodocosahexaenoic Acid as a Positron Emission Tomography Probe for Monitoring Brain Docosahexaenoic Acid Uptake Kinetics	18
Short-Term Administration of Common Anesthetics Does Not Dramatically Change the Endogenous Peptide Profile in the Rat Pituitary	18
Lipopolysaccharide Effects on Neurotransmission: Understanding Implications for Depression	18
Classics in Chemical Neuroscience: Tianeptine	18
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Benzo[d]imidazole-pyrrolo[1,2-a]pyrazine Hybrids Ameliorate Amyloid Aggregates in the Brain of Alzheimer Transgenic Mice	18
Issue Editorial Masthead	18
A Small Molecule Stabilizes the Disordered Native State of the Alzheimer’s Aβ Peptide	18
Cells Overexpressing ALS-Associated SOD1 Variants Are Differentially Susceptible to CuATSM-Associated Toxicity	18
Issue Editorial Masthead	18
Issue Editorial Masthead	18
Zalsupindole: A Non-Hallucinogenic Psychoplastogen Advancing Psychedelic-Inspired Therapeutics	18
Issue Publication Information	18
Prussian Blue Nanozyme Treatment of Ischemic Brain Injury via Reducing Oxidative Stress Inhibits Inflammation, Suppresses Apoptosis, and Promotes Neurological Recovery	18
Empirical Analysis of Drug Targets for Nervous System Disorders	18
Issue Editorial Masthead	18
Rewiring Receptor Activation: Mechanistic Insights into Toggle Switch Modulation by 25CN-NBx Compounds	17
Discovery of Pre-Clinical Candidate VU6008055/AF98943: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M₄ Muscarinic Acetylcholine Receptor Positi	17
Deciphering the Inhibitory Mechanism of Naphthoquinone–Dopamine on the Aggregation of Tau Core Fragments PHF6* and PHF6	17
Saroglitazar Enhances Memory Functions and Adult Neurogenesis via Up-Regulation of Wnt/β Catenin Signaling in the Rat Model of Dementia	17
Neurotrophic Activity and Its Modulation by Zinc Ion of a Dimeric Peptide Mimicking the Brain-Derived Neurotrophic Factor N-Terminal Region	17
Issue Editorial Masthead	17
Santonin Attenuates Alzheimer’s-Like Pathology via Multitarget Modulation of the NLRP3 Inflammasome, BDNF Signaling, and Amyloidogenic Pathways: An Integrated Experimental and Computational Study	17
Regulation of Dopamine Release by Tonic Activity Patterns in the Striatal Brain Slice	17
Dynamic Spatial Metabolomics Reveals Region-Specific Metabolic Reprogramming and Markers during Vascular Cognitive Impairment Progression	17
Edge Substitution Effects of Histidine Tautomerization Behaviors on the Structural Properties and Aggregation Properties of Aβ(1–42) Mature Fibril	17
Calycosin Inhibit PANoptosis and Alleviate Brain Damage: A Bioinformatics and Experimental Verification Approach	17
Dopaminergic Modulation and Computational ADMET Insights for the Antidepressant-like Effect of N-(3-(Phenylselanyl)prop-2-yn-1-yl)benzamide	17
Melatonin Relieves Paclitaxel-Induced Neuropathic Pain by Regulating pNEK2-Dependent Epigenetic Pathways in DRG Neurons	17
A Review of Alpha-2 Adrenergic Agents Implicated in Opioid Use Disorder	17

Hemispheric Utilization of Alpha Oscillatory Dynamics as a Unique Biomarker of Neural Compensation in Females with Fragile X Syndrome	17
Evaluation of Alpha-Synuclein and Tau Antiaggregation Activity of Urea and Thiourea-Based Small Molecules for Neurodegenerative Disease Therapeutics	17
Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Adenosine in the Control of Behavioral and Electrophysiological Modifications Caused by Chronic Stress	17
Guanidine Derivative ADS1017, a Potent Histamine H₃ Receptor Antagonist with Promising Analgesic Activity and Satisfactory Safety Profile	17
From Food Additives to Neurodegeneration: The Emerging Role of Polyphosphates in Tauopathies	17
¹H NMR Metabolomics and Lipidomics To Monitor Positive Responses in Children with Autism Spectrum Disorder Following a Guided Parental Intervention: A Pilot Study	16
Proteome Aggregation in Cells Derived from Amyotrophic Lateral Sclerosis Patients for Personalized Drug Evaluation	16
TMEM106B Fibrils from FTLD Patients and Healthy Controls	16
Bicuculline and Bumetanide Attenuate Sevoflurane-Induced Impairment of Myelination and Cognition in Young Mice	16
Dysregulation of Neuropeptide and Tau Peptide Signatures in Human Alzheimer’s Disease Brain	16
New Alpha9 nAChR Ligands Based on a 5-(Quinuclidin-3-ylmethyl)-1,2,4-oxadiazole Scaffold	16
Issue Publication Information	16
Determination of Trends Underlying Aspartic Acid Isomerization in Intact Proteins Reveals Unusually Rapid Isomerization of Tau	16
Monitoring Fast Synaptic Transmission of Neuromodulatory Transmitters To Define Drug Effects in the Brain	16
Shared and Unique Disease Pathways in Amyotrophic Lateral Sclerosis and Parkinson’s Disease Unveiled in Peripheral Blood Mononuclear Cells	16
Allopregnanolone Regulation of Phasic Dopamine Release and Motivated Behavior	16
Potential of ADAM 17 Signal Peptide To Form Amyloid Aggregates in Vitro	16
Single-Molecule Fingerprinting Reveals Different Growth Mechanisms in Seed Amplification Assays for Different Polymorphs of α-Synuclein Fibrils	16
Spontaneous Insertion of Aβ42 Dimers but Not Monomers into a Cholesterol-Rich Lipid Bilayer	16
Doubly Constrained C-terminal of Roc (COR) Domain-Derived Peptides Inhibit Leucine-Rich Repeat Kinase 2 (LRRK2) Dimerization	16
Correction to “Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor”	16
The Interplay between MiR-134/BDNF and LKB1/AMPK/SIRT1 Accentuates the Antidepressant Efficacy of Empagliflozin in Ovariectomized Rats	16
Synthesis and Preclinical Evaluation of Fluorinated 5-Azaindoles as CB2 PET Radioligands	16
Underlying Causes and Treatment Modalities for Neurological Deficits in COVID-19 and Long-COVID	15
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease	15
Longitudinal PET Imaging of the Effects of a D ₂ Dopamine Receptor Antisense Oligonucleotide	15
In Vitro and In Vivo Investigations of Chromone Derivatives as Potential Multitarget-Directed Ligands: Cognitive Amelioration Utilizing a Scopolamine-Induced Zebrafish Model	15
Molecular Insights into the Dynamics of Amyloid Fibril Growth: Elongation and Lateral Assembly of GNNQQNY Protofibrils	15
Optical Precise Ablation of Targeted Individual Neurons In Vivo	15
Griess’s Reagent-Based Azo Compounds Ameliorate Multifaceted Toxicity and Ferroptosis in Alzheimer’s Disease	15
Exploring the Therapeutic Potential of Benfotiamine in a Sporadic Alzheimer’s-Like Disease Rat Model: Insights into Insulin Signaling and Cognitive function	15
Red-Light-Photosensitized Tyrosine 10 Nitration of β-Amyloid_1–42 Diverts the Protein from Forming Toxic Aggregates	15
Role of Imaging Modalities and N -Acetylcysteine Treatment in Sepsis-Associated Encephalopathy	15
Serotonin 1A Receptors Modulate Serotonin 2A Receptor-Mediated Behavioral Effects of 5-Methoxy-N,N-dimethyltryptamine Analogs in Mice	15
Kappa Opioid Receptor Activation Induces Epigenetic Silencing of Brain-Derived Neurotropic Factor via HDAC5 in Depression	15
Multi-Target-Directed Triazole Derivatives: Design, Synthesis, and Evaluation of Synergistic Modulation in Alzheimer’s Disease	15
Dynamic and Rapid Detection of Guanosine during Ischemia	15
A Transcription Factor ZNF384, Regulated by LINC00265, Activates the Expression of IFI30 to Stimulate Malignant Progression in Glioma	15
Restoring Brain Function in Autism: GSK3β Inhibition by 6-Bromoindirubin-3′-oxime Reverses Valproic Acid-induced Neuropathology	15
Design, Synthesis, and Pharmacological Evaluation of N-Propargylated Diphenylpyrimidines as Multitarget Directed Ligands for the Treatment of Alzheimer’s Disease	15
New Insights on Protein Folding and Misfolding: Histidine Behaviors	15
Pharmacological Mechanism of the Non-hallucinogenic 5-HT_2A Agonist Ariadne and Analogs	15
Propionate Aggravates Anxiety and Cognitive Dysfunction in High-Fat Diet Mice by Activating Hippocampal Microglia-Mediated Neuroinflammation	15
Fiber Photometry Analysis of Spontaneous Dopamine Signals: The Z -Scored Data Are Not the Data	15
Unraveling the Connection of Epstein–Barr Virus and Its Glycoprotein M_146–157 Peptide with Neurological Ailments	15
TEMPOL Enhances Polyethylene Glycol Axon Fusion Following Sciatic Nerve Transection in Adult Rats	15
Understanding Neuropeptide Transmission in the Brain by Optical Uncaging and Release	15
Observation of α-Synuclein Preformed Fibrils Interacting with SH-SY5Y Neuroblastoma Cell Membranes Using Scanning Ion Conductance Microscopy	15
Profiling the Impact of mGlu₇/Elfn1 Protein Interactions on the Pharmacology of mGlu₇ Allosteric Modulators	14
Discovery of Small-Molecule Inhibitors of the KCNQ1/Kv7.1 Potassium Channel with Virtual Screening and Functional Validation in Electrophysiological Assays and KCNQ1-Knockout Neural Stem Cells	14
Issue Editorial Masthead	14
4-Amino-3′,4′-dihydroxychalcone Increases Tau Dynamics in Phase-Separated Droplets and Inhibits Tau Aggregation	14
Biophysical Characterization and Preformulation Studies of Human Mesencephalic Astrocyte-Derived Neurotropic Factor	14
Effects of Anesthetic Administration on Rat Hypothalamus and Cerebral Cortex Peptidome	14
Impact of Indole Inclusion in the Design of Multi-Tactical Metal-Binding Tetra-Aza Macrocycles that Target the Molecular Features of Neurodegeneration	14
Issue Editorial Masthead	14
Exploring the Structural Order of Condensates Formed by the PRD2 Domain of Mouse CPEB3	14
Targeting 5-HT ₇ Receptor with Biased Ligands to Alleviate Pain and Spinal Neuroinflammation	14
Characterization of (R)- and (S)-[¹⁸F]OF-NB1 in Rodents as Positron Emission Tomography Probes for Imaging GluN2B Subunit-Containing N-Methyl-d-Aspartate Rec	14
Issue Publication Information	14
Myelin Sheaths as “Accessories in Clothing” for Individualizing Every Neuron	14
Comparing Brain and Blood Lipidome Changes following Single and Repetitive Mild Traumatic Brain Injury in Rats	14
Targeting GABAergic Hypofunction Associated with Schizophrenia: Identification of α1β2γ2GABA-A Receptor Ligands with Neuroprotective and Antipsychotic Properties	14
Exogenous Huntingtin-Exon1 Aggregates Exhibit Distinct Levels of Toxicity to Caenorhabditis elegans	14
Determining Structural Changes for Ligand Recognition between Human and Rat Phosphorylated BACE1 in Silico and Its Phosphorylation by GSK3β at Thr252 by in Vitro Studies	14
The Aggregation Continuum of α-Synuclein and Its Relevance to Brain Aging	14
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Neuralized1-Mediated CPEB3 Ubiquitination in the Spinal Dorsal Horn Contributes to the Pathogenesis of Neuropathic Pain in Rats	14
Differential Effects of Nicotine, Alcohol, and Coexposure on Neuroimmune-Related Protein and Gene Expression in Corticolimbic Brain Regions of Rats	14
Issue Editorial Masthead	14
Repurposing of the PET Probe Prototype PiB for Label and Radiation-Free CEST MRI Molecular Imaging of Amyloid	13
Comprehensive Characterization of a Systematic Library of Alkyl and Alicyclic Synthetic Cannabinoids Related to CUMYL-PICA, CUMYL-BUTICA, CUMYL-CBMICA, and CUMYL-PINACA	13
Issue Editorial Masthead	13
Probing Chemical Complexity of Amyloid Plaques in Alzheimer’s Disease Mice using Hyperspectral Raman Imaging	13
Quantitative Analysis of Neuropeptide Y (NPY) and C-Terminal Glycine-Extended NPY by Mass Spectrometry and Their Localization in the Developing and Sexual Adult Mouse Brains	13
Atomic Force Microscopy Applied to the Study of Tauopathies	13
Short-Chain Fatty Acids in the Microbiota–Gut–Brain Axis: Role in Neurodegenerative Disorders and Viral Infections	13
Machine Learning-Driven Ensemble Screening of Multitarget Kinase Inhibitors for Tauopathy-Associated Neurodegeneration Using All-Atom and Steered MD Simulations	13
Ferroptosis Regulated by 5-HT3a Receptor via Calcium/Calmodulin Signaling Contributes to Neuropathic Pain in Brachial Plexus Avulsion Rat Models	13
Mitochondrial Inhibitor Rotenone Triggers and Enhances Neuronal Ferroptosis Following Intracerebral Hemorrhage	13
A Structure–Activity Relationship Study of Novel Positive Allosteric Modulators for the δ-Opioid Receptor	13
Compensatory Contextual Fear Memory Pathways Develop in the Infralimbic Cortex within 3 Days after the First Test in the Absence of the Dorsal Hippocampus	13
Curcumin Reduces Amyloid Beta Oligomer Interactions with Anionic Membranes	13
Translational Significance of GMF-β Inhibition by Indazole-4-yl-methanol in Enteric Glial Cells for Treating Multiple Sclerosis	13
Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons	13
Key Residue for Aggregation of Amyloid-β Peptides	13
Myricetin: A Potent Anti-Amyloidogenic Polyphenol against Superoxide Dismutase 1 Aggregation	13
Combinations of Vitamin A and Vitamin E Metabolites Confer Resilience against Amyloid-β Aggregation	13
Haloperidol Prevents Oxytosis/Ferroptosis by Targeting Lysosomal Ferrous Ions in a Manner Independent of Dopamine D2 and Sigma-1 Receptors	13
Substrate Selection Criteria in Regulated Intramembrane Proteolysis	13
Imidazo[2,1-b][1,3]thiazine Derivatives as Potential Modulators of Alpha-Synuclein Amyloid Aggregation	13
Psychedelic-like Activity of Norpsilocin Analogues	13
Structural Characterization of the Interaction of γ-Secretase with GSM-1 Modulator	13
Formation of Calprotectin Inhibits Amyloid Aggregation of S100A8 and S100A9 Proteins	13