ACS Medicinal Chemistry Letters

Article	Citations
Call for Papers: Fungal Pathogens – Life Cycle, Infection, Host Immunity and Drug Discovery	87
Novel Histone Acetyltransferase (HAT) Inhibitors for Treating Diseases	87
In This Issue, Volume 14, Issue 5	74
Issue Publication Information	56
Issue Editorial Masthead	49
Substituted 2,3-Benzodiazepines Derivatives as Bromodomain BRD4 Inhibitors	49
Targeting the “Undruggable” Driver Protein, KRASG12D, as Potential Therapy in Prostate Cancer	48
Discovery of Selective Inhibitors of NaV1.7 Templated on Saxitoxin as Therapeutics for Pain	48
Application of Deuterated N,N-Dimethyltryptamine in the Potential Treatment of Psychiatric and Neurological Disorders	47
Issue Publication Information	39
Emerging Techniques in Cancer Therapy: Precision Targeting for Improved Outcomes	39
Cancer-Cell-Selective Targeting by Arylcyclopropylamine–Vorinostat Conjugates	38
Novel PSMA-Targeting Radionuclide Peptidomimetics for Treating Prostate Cancer	36
Design and Characterization of 1,3-Dihydro-2H-benzo[d]azepin-2-ones as Rule-of-5 Compliant Bivalent BET Inhibitors	35
Discovery of Tumor-Targeted 6-Methyl Substituted Pemetrexed and Related Antifolates with Selective Loss of RFC Transport	34
Conformationally Restricted Analogues of α-Galactosylceramide as Adjuvant in COVID-19 Subunit Vaccine	34
From Virtual Screens to Cellular Target Engagement: New Small Molecule Ligands for the Immune Checkpoint LAG-3	34
Induction of Apoptosis in Cancer Cells by Glutathione Transferase Inhibitor Mediated Hydrophobic Tagging Molecules	33
Clozapine as an E3 Ligand for PROTAC Technology	32
Azapodophyllotoxin Causes Lymphoma and Kidney Cancer Regression by Disrupting Tubulin and Monoglycerols	32
Psychiatric Treatments with Short-Duration Psychedelics and AI-Driven Behavioral Monitoring	32
Novel Phosphorylpurinone Compounds for Treating Cancer	31
Correction to “Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay”	30
Novel Heterocyclic Pyrimidine Derivatives as GSK3α Inhibitors	28
Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology	28

Macrocyclic Oxindole Peptide Epoxyketones─A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome	27
Rational Control of Molecular Properties Is Mandatory to Exploit the Potential of PROTACs as Oral Drugs	27
Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers	27
Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors	26
Novel Tetrahydrobenzo[b]pyrazolo[3,4-e][1,4]diazepine Compounds as Oxytocin Receptor Agonists for Treating Autism Spectrum Disorders	25
Introducing the Potential Binding Interface between the TRAIL-Mimicking Peptide and DR5 via Alanine Scan	25
Tryptamines and Mental Health: Activating the 5-HT Receptor for Therapeutic Potential	25
Structure–Activity Relationship and In Silico Evaluation of cis- and trans-PCPA-Derived Inhibitors of LSD1 and LSD2	25
Bispecific Antibodies Produced via Chemical Site-Specific Conjugation Technology: AJICAP Second-Generation	24
Contemporary Computational Applications and Tools in Drug Discovery	24
Synthesis of Monofluorinated 7-Hydroxycoumarin-3-Carboxamides as Cell-Permeable Fluorescent Molecular Probes	24
Discovery of Orally Bioavailable FGFR2/FGFR3 Dual Inhibitors via Structure-Guided Scaffold Repurposing Approach	24
Methyl and Fluorine Effects in Novel Orally Bioavailable Keap1–Nrf2 PPI Inhibitor	24
Novel Triazines as NLRP3 Inhibitors for Treating Multiple Diseases	23
Thermal Stability and Utility of Dienes as Protecting Groups for Acrylamides	23
Discovery of Heteroaryl Urea Isosteres for Formyl Peptide Receptor 2 Agonists	23
Fused Bicyclic Heteroaryl Compounds as NLRP3 Inhibitors for Treating Asthma or COPD	23
Targeting Cancer: A New Era in Cancer Therapy through Immune Fitness Modulation and KRAS Degradation	23
Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation	23
Evaluating the Diversity and Target Addressability of DELs using Scaffold Analysis and Machine Learning	22
The Synergistic Effects of 5-HT2A and TRP Agonism/Antagonism in Reducing Inflammation for Enhanced Mental and Physical Health	22
Issue Editorial Masthead	22
Issue Editorial Masthead	22
Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics	22
Novel 3-Cycloaminoindole Compounds as Serotonergic Psychedelic Agents for Treating Psychosis, Mental Illness, and CNS Disorders	21
Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2	21
Fragment Ligands of the m6A-RNA Reader YTHDF2	21
Novel Piperidinylpyridinylcarbonitrile Derivatives as QPCT and QPCTL Inhibitors for Treating Cancer	21
Targeting Oncogenic Pathways: Advances in KRAS, CDK, EGFR, and PROTAC-Based Therapies	20
Charting the Chemical Space of Acrylamide-Based Inhibitors of zDHHC20	20
Pyrazole Ureas as Low Dose, CNS Penetrant Glucosylceramide Synthase Inhibitors for the Treatment of Parkinson’s Disease	20
Novel Compounds as 5-HT2A Receptor Modulators for Treating Psychiatric and Neurological Disorders	20
A Green-Absorbing, Red-Fluorescent Phenalenone-Based Photosensitizer as a Theranostic Agent for Photodynamic Therapy	19
Identification of an Allene Warhead That Selectively Targets a Histidine Residue in the Escherichia coli Oxidoreductase Enzyme DsbA	19
An Estrogen Receptor β Agonist with AR Antagonist Activity from a Modern Asymmetric De Novo Steroid Synthesis	19
ACS Medicinal Chemistry Letters Patent Highlights: A Look Back	19
Cell Permeability of Isomeric Macrocycles: Predictions and NMR Studies	18
In Retrospect: Root-Cause Analysis of Structure–Activity Relationships in IRAK4 Inhibitor Zimlovisertib (PF-06650833)	18
An Automated Purification Workflow Coupled with Material-Sparing High-Throughput 1H NMR for Parallel Medicinal Chemistry	18
Advancing New Chemical Modalities into Clinical Studies	18
Neuropharmacological Advances: Harnessing 5-HT2A Receptor Modulators and Psychoplastogens	18
Machine Learning ADME Models in Practice: Four Guidelines from a Successful Lead Optimization Case Study	18
Piperazinobenzodiazepinones: New Encephalitic Alphavirus Inhibitors via Ring Expansion of 2-Dichloromethylquinazolinones	18
Discovery of Sovleplenib, a Selective Inhibitor of Syk in Clinical Development for Autoimmune Diseases and Cancers	18
Discovery of N-(4-(Aminomethyl)phenyl)-5-methylpyrimidin-2-amine Derivatives as Potent and Selective JAK2 Inhibitors	17
3AcFNP-59 for Positron Emission Tomography Imaging of Cholesterol Trafficking and Utilization	17
Constructive On-DNA Abramov Reaction and Pudovik Reaction for DEL Synthesis	17
Heparan Sulfate-Mimicking Glycopolymers Bind SARS-CoV-2 Spike Protein in a Length- and Sulfation Pattern-Dependent Manner	17
Announcing the Early Career Board of ACS Medicinal Chemistry Letters	17
Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2	16

Thermal Degradation Kinetics and pH–Rate Profile of Verbascoside and Stability Improvement by Solid Lipid Nanoparticles	16
Lead Optimization: Synthesis and Biological Evaluation of PBT-1 Derivatives as Novel Antitumor Agents	16
SAR Study of 4,8-Disubstituted Pyrimido[5,4-d]pyrimidines Exhibiting Antitrypanosomal and Antileishmanial Activity	16
N-Arylsulfonylated C-Homoaporphines as a New Class of Antiplatelet and Antimicrobial Agents	16
In-Silico Screening-Based Discovery of New Natural eEF2K Inhibitors with Neuritogenic Activity	16
Interleukin-17A Peptide Aptamers with an Unexpected Binding Moiety Selected by cDNA Display under Heterogenous Conditions	16
Novel Papain-Like Protease Inhibitors for Treating Viral Infections, in Particular Coronavirus Infections	16
Synthesis and Evaluation of Halogenated Pralidoximes in Reactivation of Organophosphate-Inhibited Cholinesterases	16
Fragment-Based Dynamic Combinatorial Chemistry for Identification of Selective α-Glucosidase Inhibitors	16
(−)-Epigallocatechin Gallate is a Noncompetitive Inhibitor of NAD Kinase	15
Discovery of Pyridone-Substituted Triazolopyrimidine Dual A2A/A1 AR Antagonists for the Treatment of Ischemic Stroke	15
Synthesis and Preclinical Evaluation of Novel 68Ga-DOTA-RBB as Potential PET Radiotracer for Imaging CDK4/6 in Tumors	15
Enantioselective Bioreduction of Medicinally Relevant Nitrogen-Heteroaromatic Ketones	15
The Growing Importance of Chirality in 3D Chemical Space Exploration and Modern Drug Discovery Approaches for Hit-ID	15
Lathyrane Diterpenoids as Novel hPXR Agonists: Isolation, Structural Modification, and Structure–Activity Relationships	15
Exploiting Solvent Exposed Salt-Bridge Interactions for the Discovery of Potent Inhibitors of SOS1 Using Free-Energy Perturbation Simulations	15
Novel Furopyridine and Furopyrimidine Compounds as PI4K Inhibitors for Treating Malaria and Viral Infection	15
Quantum Mechanics-Based Ranking of Predicted Proteolysis Targeting Chimeras-Mediated Ternary Complexes	15
In Silico Optimized Stapled Peptides Targeting WASF3 in Breast Cancer	15
Issue Publication Information	14
Issue Publication Information	14
Development of BET Inhibitors as Potential Treatments for Cancer: Optimization of Pharmacokinetic Properties	14
Discovery of Potent and Oral Bioavailable MAT2A Inhibitors for the Treatment of MTAP-Deleted Tumors	14
Issue Publication Information	14
Issue Publication Information	14
Issue Publication Information	14
Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable In Vivo Studies: Discovery of TDI-11055	14
Targeted Degradation of Androgen Receptor for the Potential Treatment of Prostate Cancer	14
Issue Publication Information	14
Novel Imidazotriazine Derivatives as IL-17 Modulators for Treating Inflammatory and Autoimmune Disorders	14
Photoaffinity Probe Reveals the Potential Target of Harringtonolide for Cancer Cell Migration Inhibition	14
Novel Small Molecule RNA m6A Demethylase AlkBH5 Inhibitors for Treating Cancer	14
Issue Editorial Masthead	14
Design, Synthesis, and Biological Activity of l-1′-Homologated Adenosine Derivatives	13
Hybrids of Membrane-Translocating Antimicrobial Peptides Show Enhanced Activity through Membrane Permeabilization	13
The BASHY Platform Enables the Assembly of a Fluorescent Bortezomib–GV1001 Conjugate	13
Exploring the Therapeutic Potential of Entheogens in Postoperative Cognitive Decline and Psychological Resilience	13
SiRNAs with Neutral Phosphate Triester Hydrocarbon Tails Exhibit Carrier-Free Gene-Silencing Activity	13
Ir(III) Complex Dimer Nanoparticles for Photodynamic Therapy	13
Lipase-Catalyzed Synthesis and Biological Evaluation of N-Picolineamides as Trypanosoma cruzi Antiproliferative Agents	13
Identification and In Silico Binding Study of a Highly Potent DENV NS2B-NS3 Covalent Inhibitor	13
Small Molecules Blocking the Assembly of TCAB1 and Telomerase Complexes: Lead Discovery and Biological Activity	13
Introducing Conformational Restraints on 25CN-NBOH: A Selective 5-HT2A Receptor Agonist	13
Discovery of First-in-Class BAZ2A/B and BAZ2B-Selective Degraders	13
Synthesis, Anti-Plasmodial Activities, and Mechanistic Insights of 4-Aminoquinoline-Triazolopyrimidine Hybrids	13
Discovery of Novel Pyrazolopyrimidines as Potent, Selective, and Orally Bioavailable Inhibitors of ALK2	13
Structure–Activity Relationships for the N-Me- Versus N-H-Amide Modification to Macrocyclic ent-Verticilide Antiarrhythmics	13
Issue Editorial Masthead	13
Spiro(isobenzofuranazetidine) Compounds for Treating Autoimmune Diseases	13
Novel Plasma Kallikrein Inhibitors for Treating Hereditary Angioedema, Diabetic Macular Edema, and Diabetic Retinopathy	13
In the Quest for Potent and Selective Malic Enzyme 3 Inhibitors for the Treatment of Pancreatic Ductal Adenocarcinoma	13
Indole-Containing Pyrazino[2,1-b]quinazoline-3,6-diones Active against Plasmodium and Trypanosomatids	13
Improving the Adjuvanticity of Small Molecule Immune Potentiators Using Covalently Linked NF-κB Modulators	12
Issue Editorial Masthead	12
Amino-cyclohexane Carboxylic Acid Inhibitors of Arginase	12
In This Issue, Volume 12, Issue 7	12
Re-evaluation of Cyclic Peptide Binding to Neurotensin Receptor 1 by Shifting the Peptide Register during Synthesis	12
Issue Publication Information	12
2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors	12
Discovery of CVN636: A Highly Potent, Selective, and CNS Penetrant mGluR7 Allosteric Agonist	12
Application of Rapidly Accelerating Fibrosarcoma Protein Degraders in Drug Discovery	12
In This Issue, Volume 13, Issue 1	12
Recent Developments in Mass Spectrometry to Support Next-Generation Synthesis and Screening	12
Peripherally Restricted Fused Heterocyclic Peptidomimetic Multifunctional Opioid Agonists as Novel, Potent Analgesics	12
Novel Pyrimidinyl Sulfonamide Derivatives as GPR17 Modulators	12
Enantiopure Benzofuran-2-carboxamides of 1-Aryltetrahydro-β-carbolines Are Potent Antimalarials In Vitro	12
Issue Editorial Masthead	12
Targeting KRAS G12D Mutant for the Potential Treatment of Pancreatic Cancer	12
Issue Publication Information	12
Synthesis and Evaluation of Benzylamine Inhibitors of Neuropathogenic Naegleria fowleri “Brain-Eating” Amoeba	11
Discovery of 5,7-Dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-ones as Highly Selective CDK2 Inhibitors	11
Reducing Self-Assembly by Increasing Net Charge: Effect on Biological Activity of Mastoparan C	11
Fragment-Based Discovery of Drug-like LRH-1 Agonists	11
Accelerated Discovery of Macrocyclic CDK2 Inhibitor QR-6401 by Generative Models and Structure-Based Drug Design	11
Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field	11
Novel Nonpeptide as Oxytocin Receptor Agonist	11
Structure–Activity Relationship Study of 1H-Pyrrole-3-carbonitrile Derivatives as STING Receptor Agonists	11
Synthesis and Evaluation of Novel meso-Tetraphenyltetrabenzoporphyrins for Photodynamic Therapy	11
A New Highly Deuterated [18F]AV-45, [18F]D15FSP, for Imaging β-Amyloid Plaques in the Brain	11
Innovative Psychedelic Therapies: Harnessing 5-MeO-DMT and DMT for Mental Health Treatment	11

Inhibitors of the Cyclic GMP-AMP Synthase (cGAS) as Potential Treatment for Autoimmune and Inflammatory Diseases	11
Beyond 20 in the 21st Century: Prospects and Challenges of Non-canonical Amino Acids in Peptide Drug Discovery	11
Design, Synthesis, and Evaluation of 8-(o-Tolyl)quinazoline Derivatives as Small-Molecule PD-1/PD-L1 Antagonists	11
Synthesis and Monoamine Oxidase Inhibitory Activity of Halogenated Flavones	11
Identification of Boc2Lys-Linked Ethacrynic Acid and Its Analogues As Efficient Glutathione S-Transferase Degraders	11
Tetrazole Derivatives as TRPA1 Inhibitors for Treating Idiopathic Lung Disease or Cough	11
Enantioselective Synthesis and Profiling of Potent, Nonlinear Analogues of Antimalarial Tetraoxanes E209 and N205	11
Potentiometric Determination of Acid Dissociation Constants (pKa) for an Anticancer Pyrrole-Imidazole Polyamide	11
N-Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28–Let-7 Interaction	11
Discovery of Dolastatinol: A Synthetic Analog of Dolastatin 10 and Low Nanomolar Inhibitor of Tubulin Polymerization	11
Targeting KRAS Mutant Protein Inhibitor for Potential Treatment in Cancer	10
The Inhibitors of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 (MALT-1) Protease as Potential Treatment of ABC-DLBCL and Similar Diseases	10
Discovery of Selective Aldehyde Dehydrogenase Inhibitors for the Treatment of Cancer	10
Synthesis of Benzoazepine Derivatives via Azide Rearrangement and Evaluation of Their Antianxiety Activities	10
In This Issue, Volume 12, Issue 11	10
Inhibitors of Nav1.7 for the Treatment of Pain	10
Development of BODIPY FL SNS 032 as a Versatile Probe for Constitutive Androstane Receptor and Multiple Kinases	10
Steroid–Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes	10
4-Oxo-β-lactams as Covalent Inhibitors of the Mitochondrial Intramembrane Protease PARL	10
Issue Publication Information	10
How a Blockchain Approach Can Improve Data Reliability in the COVID-19 Pandemic	10
Bioisostere Effects on the EPSA of Common Permeability-Limiting Groups	10
Novel Pyridazin-3(2H)-one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity	10
ACS Medicinal Chemistry Letters: An Innovation Ten Years in the Making	10
Biological Effects of Modifications of the Englerin A Glycolate	10
9,10-Bis[(4-(2-hydroxyethyl)piperazine-1-yl)prop2-yne-1-yl]anthracene: G-Quadruplex Selectivity and Anticancer Activity	10
Synthesis and Determination of Anticancer Activity of Dicobalt Hexacarbonyl 2′-Deoxy-5-alkynylfuropyrimidines	10
Mining Druggable Sites in Influenza A Hemagglutinin: Binding of the Pinanamine-Based Inhibitor M090	10
Issue Publication Information	10
Novel Aminocyclobutanes as Monoacylglycerol Lipase Modulators	10
Decarboxylative Cross-Coupling: A Radical Tool in Medicinal Chemistry	10
Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFRT790M/C797S Mutants	10
Pioneering Changes in Psychiatry: Biomarkers, Psychedelics, and AI	10
Intramolecular Ring-Opening Decomposition of Aryl Azetidines	10
A Warhead Substitution Study on the Coronavirus Main Protease Inhibitor Nirmatrelvir	10
Potent, Selective, and Orally Bioavailable Quinazoline-Based STK17A/B Dual Inhibitors	10
Discovery of Non-Covalent Inhibitors for SARS-CoV-2 PLpro: Integrating Virtual Screening, Synthesis, and Experimental Validation	10
Discovery of a Novel Photocaged PI3K Inhibitor Capable of Real-Time Reporting of Drug Release	10
Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors	9
Novel Lactams as Cbl-b Inhibitors for Treating Cancer	9
Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries	9
Identification, Synthesis, and Characterization of a Major Circulating Human Metabolite of TRPV4 Antagonist GSK2798745	9
Novel Piperidine Substituted Pyrazolopyrimidine Derivatives as SGK1 Inhibitors for Treating Cardiovascular Diseases	9
BTZ-Derived Benzisothiazolinones with In Vitro Activity against Mycobacterium tuberculosis	9
Allostery Illuminated: Harnessing AI and Machine Learning for Drug Discovery	9
RNA: Opening New Doors in Medicinal Chemistry, a Special Issue	9
A Neutral Flavin–Triphenylamine Probe for Mitochondrial Bioimaging under Different Microenvironments	9
Novel Thienopyrrole Compounds for Treating Autoimmune Diseases and Inflammatory Conditions	9
Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression	9
MALT1 Inhibitors for Treating Cancer and Immunological Diseases	9
Modulation of KRAS Mutant by Inhibiting PLK1 Kinase in Cancer Therapeutics	9
Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds	9
Structure-Based Design of Novel TLR7/8 Agonist Payloads Enabling an Immunomodulatory Conjugate Approach	9
Inhibitors of Interleukin 4 Induced Protein 1 (IL4I1) as Potential Treatment for Cancer	9
Issue Publication Information	9
Relevance of the Trillion-Sized Chemical Space “eXplore” as a Source for Drug Discovery	9
Recent Discovery of PARP7 Inhibitors as Anticancer Agents	9
Novel 2-Pyrrolidone Derivatives as Negative Allosteric Modulators of GluN2B-Containing NMDA Receptors	9
Issue Publication Information	9
Correction to “Study of Chalcogen Aspirin Derivatives with Carbonic Anhydrase Inhibitory Properties for Treating Inflammatory Pain”	9
Novel Compounds as NLRP3 Inhibitors for Treating Asthma or COPD	9
DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2–p53 Inhibitor	9
Discovery of Novel Pyrimidine Derivatives as Human Pin1 Covalent Inhibitors	9
In This Issue, Volume 15, Issue 4	9
Targeting the Inhibition of B-Cell Lymphoma 2 Protein for the Treatment of Cancer	8
Integrated Advancements in Neuroplasticity, Psychedelic Therapeutics, and AI-Driven Innovations for Precision Medicine	8
Design and Assessment of First-Generation Heterobifunctional PPARα/STING Modulators	8
Structure–Activity Relationship of Anti-Mycobacterium abscessus Piperidine-4-carboxamides, a New Class of NBTI DNA Gyrase Inhibitors	8
Addition to “The Death of the Strategy of Classical Chiral Switches Is an Exaggeration”	8
Call for Papers: Exploring the Use of AI/ML Technologies in Medicinal Chemistry and Drug Discovery	8
Issue Publication Information	8
Novel 6-Substituted-3-Phenylisoindolin-1-ones as Cbl-B Inhibitors for Treating Cancer	8
Investigation of Isobactin Analogues of Teixobactin	8
Development of Conformationally Restricted Negamycin Derivatives for Potent Readthrough Activity	8
Evaluation of the Indazole Analogs of 5-MeO-DMT and Related Tryptamines as Serotonin Receptor 2 Agonists	8
Discovery of First-in-Class Small Molecule Inhibitors of Lymphocyte Activation Gene 3 (LAG-3)	8
Ligand Design with Accelerated Disulfide Formation with Serum Albumin to Extend Blood Retention	8
Synthesis of Marine-Inspired Multifaceted DNA Damaging Spirooxindoles Combating NSCLC and Associated Bacterial Infection	8
Integrating Neuroprotective and Anti-inflammatory Strategies in the Development of PI3K Inhibitors for Enhanced Cancer Therapy	8
Novel AHR Agonists for Treating Psoriasis	8
Novel Macrocyclic Antagonists of the CGRP Receptor Part 2: Stereochemical Inversion Induces an Unprecedented Binding Mode	8
Application of Compositions Comprising a KRAS G12C Inhibitor and an EGFR Inhibitor for the Potential Treatment of Cancer	8
Issue Publication Information	8
Structural Evaluations of a Selective Human STINGA230 Agonist and Its Use in Macrophage Immunotherapies	8
Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol	8
Novel Histone Deacetylase Inhibitors for Treating HIV Infection	8
Total Synthesis as Training for Medicinal Chemistry	8
Bicyclic Inhibitors of Branched-Chain α-Keto Acid Dehydrogenase Kinase (BDK) with In Vivo Activity	8
A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors	8
Innovations in Precision Oncology: Biomarker-Driven Approaches for Enhanced Cancer Therapy	8
Insight on Some Newly Synthesized Trisubstituted Imidazolinones as VEGFR-2 Inhibitors	8
Exploring the 1-(4-Nitrophenyl)-3-arylprop-2-en-1-one Scaffold for the Selective Inhibition of Monoamine Oxidase B	8
Identification of 5-Thiocyanatothiazol-2-amines Disrupting WDR5-MYC Protein–Protein Interactions	8
Heterocyclic Compounds as Dihydroorotate Dehydrogenase Inhibitors for Treating Acute Myelogenous Leukemia (AML)	8
Malaria Box-Inspired Discovery of N-Aminoalkyl-β-carboline-3-carboxamides, a Novel Orally Active Class of Antimalarials	8