World Journal of Gastrointestinal Oncology

Article	Citations
Young-onset colorectal cancer: A review	47
Early-onset colorectal cancer: Current insights and future directions	38
Liquid biopsy in cholangiocarcinoma: Current status and future perspectives	34
Colorectal cancer screening in the COVID-19 era	31
Propofol induces ferroptosis and inhibits malignant phenotypes of gastric cancer cells by regulating miR-125b-5p/STAT3 axis	29
Neoadjuvant chemotherapy for colorectal liver metastases: A contemporary review of the literature	27
Nanotechnology and pancreatic cancer management: State of the art and further perspectives	24
Small bowel adenocarcinoma: An overview	23
Colorectal cancer carcinogenesis: From bench to bedside	22
Diagnostic value of four serum exosome microRNAs panel for the detection of colorectal cancer	21
Microbiome and colorectal carcinogenesis: Linked mechanisms and racial differences	21
Diverse roles of FOXO family members in gastric cancer	21
Radiomics in hepatocellular carcinoma: A state-of-the-art review	21
Helicobacter pylori, gastric microbiota and gastric cancer relationship: Unrolling the tangle	20
Inflammatory bowel disease-related colorectal cancer: Past, present and future perspectives	20
Helicobacter pylori infection and other bacteria in pancreatic cancer and autoimmune pancreatitis	20
BRAFV600E mutant colorectal cancer cells mediate local immunosuppressive microenvironment through exosomal long noncoding RNAs	20
Overgrowth of Lactobacillus in gastric cancer	20
Regulatory RNAs, microRNA, long-non coding RNA and circular RNA roles in colorectal cancer stem cells	20
Unique situation of hepatocellular carcinoma in Egypt: A review of epidemiology and control measures	19
Claudin 18.2 is a potential therapeutic target for zolbetuximab in pancreatic ductal adenocarcinoma	19
Development of artificial intelligence technology in diagnosis, treatment, and prognosis of colorectal cancer	19
Recent advances in targeted therapy for pancreatic adenocarcinoma	18
Endoscopic or percutaneous biliary drainage in hilar cholangiocarcinoma: When and how?	18
Early diagnosis and therapeutic strategies for hepatocellular carcinoma: From bench to bedside	18

Colorectal cancer in Arab world: A systematic review	18
Gallbladder cancer: Historical treatment and new management options	17
Gastric epithelial histology and precancerous conditions	17
Nutritional therapy for hepatocellular carcinoma	17
Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway	17
Efficacy and safety of anti-PD-1/anti-PD-L1 antibody therapy in treatment of advanced gastric cancer or gastroesophageal junction cancer: A meta-analysis	16
Digestive cancer incidence and mortality among young adults worldwide in 2020: A population-based study	16
Minimally invasive surgical treatment of intrahepatic cholangiocarcinoma: A systematic review	15
Pathological, molecular, and clinical characteristics of cholangiocarcinoma: A comprehensive review	15
Myeloid-derived suppressor cells in gastrointestinal cancers: A systemic review	15
Immunotherapy in liver transplantation for hepatocellular carcinoma: Pros and cons	14
Programmed death 1, ligand 1 and 2 correlated genes and their association with mutation, immune infiltration and clinical outcomes of hepatocellular carcinoma	14
Pancreatic intraductal papillary mucinous neoplasms: Current diagnosis and management	14
Review of incidence and outcomes of treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis	14
Management of obstructive colon cancer: Current status, obstacles, and future directions	14
Current role of hepatopancreatoduodenectomy for the management of gallbladder cancer and extrahepatic cholangiocarcinoma: A systematic review	13
Clinicopathological characteristics and prognosis of 77 cases with type 3 gastric neuroendocrine tumours	13
Diagnostic performance of narrow-band imaging international colorectal endoscopic and Japanese narrow-band imaging expert team classification systems for colorectal cancer and precancerous lesions	13
Advances in postoperative adjuvant therapy for primary liver cancer	13
Biomarkers for hepatocellular carcinoma based on body fluids and feces	13
Highly accurate colorectal cancer prediction model based on Raman spectroscopy using patient serum	13
Immune checkpoint inhibitor-mediated colitis in gastrointestinal malignancies and inflammatory bowel disease	13
Decreased expression of the long non-coding RNA HOXD-AS2 promotes gastric cancer progression by targeting HOXD8 and activating PI3K/Akt signaling pathway	13
Management of single pulmonary metastases from colorectal cancer: State of the art	12
Multimodal treatment in oligometastatic gastric cancer	12
Application of the woodchuck animal model for the treatment of hepatitis B virus-induced liver cancer	12
Neoantigen vaccine: An emerging immunotherapy for hepatocellular carcinoma	12
Atezolizumab plus bevacizumab versus sorafenib or atezolizumab alone for unresectable hepatocellular carcinoma: A systematic review	12
Primary malignant vascular tumors of the liver in children: Angiosarcoma and epithelioid hemangioendothelioma	12
Poorly cohesive cells gastric carcinoma including signet-ring cell cancer: Updated review of definition, classification and therapeutic management	12
Recent update on comprehensive therapy for advanced hepatocellular carcinoma	12
Gastric cancer: An epigenetic view	12
Non-surgical treatment of hilar cholangiocarcinoma	12
Prognostic impact of at least 12 lymph nodes after neoadjuvant therapy in rectal cancer: A meta-analysis	11
Total neoadjuvant therapy vs standard therapy of locally advanced rectal cancer with high-risk factors for failure	11
Neutrophile-to-lymphocyte, lymphocyte-to-monocyte, and platelet-to-lymphocyte ratios as prognostic and response biomarkers for resectable locally advanced gastric cancer	11
Role of exosomal long non-coding RNAs in colorectal cancer	11
Lateral pelvic lymph nodes for rectal cancer: A review of diagnosis and management	11
Thermal ablation and immunotherapy for hepatocellular carcinoma: Recent advances and future directions	11
LncRNA C9orf139 can regulate the growth of pancreatic cancer by mediating the miR-663a/Sox12 axis	11
Bromodomain and extra-terminal inhibitors emerge as potential therapeutic avenues for gastrointestinal cancers	11
Crosstalk between gut microbiota and COVID-19 impacts pancreatic cancer progression	11
Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways	11
Molecular regulatory mechanism of ferroptosis and its role in gastrointestinal oncology: Progress and updates	11
Traditional Chinese medicine for transformation of gastric precancerous lesions to gastric cancer: A critical review	11
Mesenchymal stem cell-derived exosomes for gastrointestinal cancer	11
Gut microbiome in non-alcoholic fatty liver disease associated hepatocellular carcinoma: Current knowledge and potential for therapeutics	11
Anatomical vs nonanatomical liver resection for solitary hepatocellular carcinoma: A systematic review and meta-analysis	11
Association between intestinal neoplasms and celiac disease: A review	10
Liquid biopsy approach to pancreatic cancer	10

Molecular testing for colorectal cancer: Clinical applications	10
Exosomes as potential diagnosis and treatment for liver cancer	10
Extracellular vesicles: General features and usefulness in diagnosis and therapeutic management of colorectal cancer	10
Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model	10
Neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 as prognostic markers for advanced pancreatic cancer patients receiving first-line chemotherapy	10
Outcomes of curative esophageal cancer surgery in elderly: A meta-analysis	10
Update on the management of the gastrointestinal effects of radiation	10
Novel perspective in pancreatic cancer therapy: Targeting ferroptosis pathway	10
Influence of primary tumor location and resection on survival in metastatic colorectal cancer	10
Immune evasion mechanisms and therapeutic strategies in gastric cancer	10
Glutamine deprivation impairs function of infiltrating CD8+ T cells in hepatocellular carcinoma by inducing mitochondrial damage and apoptosis	9
Is the combination of immunotherapy with conventional chemotherapy the key to increase the efficacy of colorectal cancer treatment?	9
Research progress of integrated traditional Chinese and Western medicine in the treatment of advanced gastric cancer	9
Sporadic fundic gland polyps with dysplasia or carcinoma: Clinical and endoscopic characteristics	9
Fibrolamellar hepatocellular carcinoma: A rare but unpleasant event	9
Characterization of metabolic landscape in hepatocellular carcinoma	9
Role of autophagy in cholangiocarcinoma: An autophagy-based treatment strategy	9
Effects ofHelicobacter pyloriinfection in gastrointestinal tract malignant diseases: From the oral cavity to rectum	9
Endoscopic ultrasound assessment and tissue acquisition of mediastinal and abdominal lymph nodes	9
Current controversies and advances in the management of pancreatic adenocarcinoma	9
Incidence and prevalence of gastric neuroendocrine tumors in patients with chronic atrophic autoimmune gastritis	9
VCAN, expressed highly in hepatitis B virus-induced hepatocellular carcinoma, is a potential biomarker for immune checkpoint inhibitors	9
Cryptotanshinone inhibits cytotoxin-associated gene A-associated development of gastric cancer and mucosal erosions	8
Practical considerations for colorectal cancer screening in older adults	8
Prognostic value of claudin 18.2 expression in gastric adenocarcinoma	8
Challenges and exploration for immunotherapies targeting cold colorectal cancer	8
Macrophages play a role in inflammatory transformation of colorectal cancer	8
Current status of non-surgical treatment of locally advanced pancreatic cancer	8
MicroRNA expression in inflammatory bowel disease-associated colorectal cancer	8
Endoscopic ultrasound-guided ablation of solid pancreatic lesions: A systematic review of early outcomes with pooled analysis	8
Relation between skeletal muscle volume and prognosis in rectal cancer patients undergoing neoadjuvant therapy	8
Outcomes of neoadjuvant chemoradiotherapy followed by radical resection for T4 colorectal cancer	8
Intratumour microbiome of pancreatic cancer	8
Proliferating cell nuclear antigen clamp associated factor, a potential proto-oncogene with increased expression in malignant gastrointestinal tumors	8
Endoscopic radiofrequency ablation for malignant biliary obstruction	8
Engineering nanotheranostic strategies for liver cancer	8
Plexiform fibromyxoma: Review of rare mesenchymal gastric neoplasm and its differential diagnosis	8
Solid extraintestinal malignancies in patients with inflammatory bowel disease	8
Low body mass index is an independent predictor of poor long-term prognosis among patients with resectable gastric cancer	8
Sarcopenia in pancreatic cancer: Effect on patient outcomes	8
What is the best surgical procedure of transverse colon cancer? An evidence map and minireview	8
Familial adenomatous polyposis and changes in the gut microbiota: New insights into colorectal cancer carcinogenesis	8
Role of three-dimensional printing and artificial intelligence in the management of hepatocellular carcinoma: Challenges and opportunities	8
Hypoxia and its impact on the tumour microenvironment of gastroesophageal cancers	8
Comparison of tumor regression grading systems for locally advanced gastric adenocarcinoma after neoadjuvant chemotherapy	7
Comparison of survival between adolescent and young adult vs older patients with hepatocellular carcinoma	7
Role of neoadjuvant therapy for nonmetastatic pancreatic cancer: Current evidence and future perspectives	7
Pancreatic head vs pancreatic body/tail cancer: Are they different?	7
Sex as an effect modifier in the association between alcohol intake and gastric cancer risk	7
Clinical significance of molecular subtypes of gastrointestinal tract adenocarcinoma	7
Characterizing the patient experience during neoadjuvant therapy for pancreatic ductal adenocarcinoma: A qualitative study	7
Vasoactive intestinal peptide secreting tumour: An overview	7
Laparoscopic liver resection for colorectal liver metastases — short- and long-term outcomes: A systematic review	7
Clinicopathological differences, risk factors and prognostic scores for western patients with intestinal and diffuse-type gastric cancer	7
Robotic resection of liver focal nodal hyperplasia guided by indocyanine green fluorescence imaging: A preliminary analysis of 23 cases	7
How the COVID-19 pandemic has affected the colorectal cancer screening in Italy: A minireview	7
Cuproptosis-related long non-coding RNAs model that effectively predicts prognosis in hepatocellular carcinoma	7
Can dietary flavonoids be useful in the personalized treatment of colorectal cancer?	7
Portal vein embolization failure: Current strategies and future perspectives to improve liver hypertrophy before major oncological liver resection	7
Scoping out the future: The application of artificial intelligence to gastrointestinal endoscopy	7
Trimodality treatment in gastric and gastroesophageal junction cancers: Current approach and future perspectives	7
Preventive and inhibitive effects of Yiwei Xiaoyu granules on the development and progression of spasmolytic polypeptide-expressing metaplasia lesions	6
Immunotherapy for nonalcoholic fatty liver disease-related hepatocellular carcinoma: Lights and shadows	6
Comprehensive molecular characterization and identification of prognostic signature in stomach adenocarcinoma on the basis of energy-metabolism-related genes	6
Outcomes of curative liver resection for hepatocellular carcinoma in patients with cirrhosis	6
Screening strategy for gastrointestinal and hepatopancreatobiliary cancers in cystic fibrosis	6
Stereotactic radiotherapy for intrahepatic cholangiocarcinoma	6
Molecular-targeted therapy toward precision medicine for gastrointestinal caner: Current progress and challenges	6
Clinical implications of interleukins-31, 32, and 33 in gastric cancer	6
Second-line therapy for advanced hepatocellular carcinoma with regorafenib or cabozantinib: Multicenter French clinical experience in real-life after matching	6
Survival effect of probiotics in a rat model of colorectal cancer treated with capecitabine	6
Berberine retarded the growth of gastric cancer xenograft tumors by targeting hepatocyte nuclear factor 4α	6
Hemoglobin, albumin, lymphocyte, and platelet score as a predictor of prognosis in metastatic gastric cancer	6
Proteasome regulators in pancreatic cancer	6
Same day yttrium-90 radioembolization with single photon emission computed tomography/computed tomography: An opportunity to improve care during the COVID-19 pandemic and beyond	6
Emerging role of caldesmon in cancer: A potential biomarker for colorectal cancer and other cancers	6
Potential utility of liquid biopsies in the management of patients with biliary tract cancers: A review	6
Effects of dietary zinc deficiency on esophageal squamous cell proliferation and the mechanisms involved	6
Radiofrequency ablation in the management of primary hepatic and biliary tumors	6
Role of mammalian target of rapamycin complex 2 in primary and secondary liver cancer	6

Effect of oncometabolic surgery on gastric cancer: The remission of hypertension, type 2 diabetes mellitus, and beyond	6
Angiotensin-converting enzyme 2 connects COVID-19 with cancer and cancer immunotherapy	6
Clinical management for malignant afferent loop obstruction	6
Latest therapeutic target for gastric cancer: Anthrax toxin receptor 1	6
Predictors for malignant potential and deep submucosal invasion in colorectal laterally spreading tumors	6
Esophageal cancer screening, early detection and treatment: Current insights and future directions	6
Increased CD4/CD8 Lymphocyte ratio predicts favourable neoadjuvant treatment response in gastric cancer: A prospective pilot study	6
Molecular methods for colorectal cancer screening: Progress with next-generation sequencing evolution	6
High expression of protein phosphatase 2 regulatory subunit B'' alpha predicts poor outcome in hepatocellular carcinoma patients after liver transplantation	6
Angiogenesis in gastrointestinal stromal tumors: From bench to bedside	6
Should we resect colorectal cancer in patients over the age of 85?	6
Clinical efficacy and prognostic risk factors of endoscopic radiofrequency ablation for gastric low-grade intraepithelial neoplasia	6
Serum vascular endothelial growth factor as a tumor marker for hepatocellular carcinoma in hepatitis C virus-related cirrhotic patients	6
Gut microbiota and immune system in liver cancer: Promising therapeutic implication from development to treatment	5
Yield of surgery in solid pseudopapillary neoplasms of the pancreas: A case series and literature review	5
Lipid metabolism of hepatocellular carcinoma impacts targeted therapy and immunotherapy	5
New trends in diagnosis and management of gallbladder carcinoma	5
Baseline neutrophil-lymphocyte ratio and platelet-lymphocyte ratio appear predictive of immune treatment related toxicity in hepatocellular carcinoma	5
Lymph node regression grading of locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy	5
Shuyu pills inhibit immune escape and enhance chemosensitization in hepatocellular carcinoma	5
Circular RNAs in hepatocellular carcinoma: Recent advances	5
Cutaneous metastases of pancreatic carcinoma to the labia majora: A case report and review of literature	5
Statin as a therapeutic agent in gastroenterological cancer	5
Role of ferroptosis in colorectal cancer	5
Cost-effective low-coverage whole-genome sequencing assay for the risk stratification of gastric cancer	5
Endoscopic papillectomy for ampullary adenomatous lesions: A literature review	5
Regorafenib combined with programmed cell death-1 inhibitor against refractory colorectal cancer and the platelet-to-lymphocyte ratio’s prediction on effectiveness	5
Risk factors, prognostic predictors, and nomograms for pancreatic cancer patients with initially diagnosed synchronous liver metastasis	5
Effect of obesity on post-operative outcomes following colorectal cancer surgery	5
New frontiers in liver ultrasound: From mono to multi parametricity	5
Neoadjuvant therapy in resectable pancreatic cancer: A promising curative method to improve prognosis	5
Computed tomography-based radiomic to predict resectability in locally advanced pancreatic cancer treated with chemotherapy and radiotherapy	5
Prospects and applications of enucleation in solid pseudopapillary neoplasms of the pancreas	5
Deltonin enhances gastric carcinoma cell apoptosis and chemosensitivity to cisplatin via inhibiting PI3K/AKT/mTOR and MAPK signaling	5
Application of metabolomics in clinical and laboratory gastrointestinal oncology	5
Role of endoscopic ultrasound in anticancer therapy: Current evidence and future perspectives	5
Clinical implications and perspectives of portal venous circulating tumor cells in pancreatic cancer	5
“Cold” colorectal cancer faces a bottleneck in immunotherapy	5
Rare common bile duct metastasis of breast cancer: A case report and literature review	5
Fecal microbial biomarkers combined with multi-target stool DNA test improve diagnostic accuracy for colorectal cancer	5
Interleukin-34 promotes the proliferation and epithelial-mesenchymal transition of gastric cancer cells	5
Current guidelines in the surgical management of hereditary colorectal cancers	5
B7 homologue 3 as a prognostic biomarker and potential therapeutic target in gastrointestinal tumors	5
Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma	5
Genome-wide CRISPR-Cas9 screening identifies that hypoxia-inducible factor-1a-induced CBX8 transcription promotes pancreatic cancer progression via IRS1/AKT axis	5
RNA-Seq profiling of circular RNAs in human colorectal cancer 5-fluorouracil resistance and potential biomarkers	5
Duodenal-type follicular lymphoma more than 10 years after treatment intervention: A retrospective single-center analysis	5
Combined treatments in hepatocellular carcinoma: Time to put them in the guidelines?	5
Oxidative imbalance increases the risk for colonic polyp and colorectal cancer development	5
Role of autophagy in gastric carcinogenesis	5
Evidence based tools to improve efficiency of currently administered oncotherapies for tumors of the hepatopancreatobiliary system	4
Overexpression of ELL-associated factor 2 suppresses invasion, migration, and angiogenesis in colorectal cancer	4
Research progress of ginger in the treatment of gastrointestinal tumors	4
Digital single-operator cholangioscopy for biliary stricture after cadaveric liver transplantation	4
Moving forward in the treatment of cholangiocarcinoma	4
Neoadjuvant chemotherapy without radiation as a potential alternative treatment for locally advanced rectal cancer: A meta-analysis	4
O6-methylguanine DNA methyltransferase is upregulated in malignant transformation of gastric epithelial cells via its gene promoter DNA hypomethylation	4
Crohn’s disease with infliximab treatment complicated by rapidly progressing colorectal cancer: A case report	4
Does the addition of Braun anastomosis to Billroth II reconstruction on laparoscopic-assisted distal gastrectomy benefit patients?	4
Deep learning-based radiomics based on contrast-enhanced ultrasound predicts early recurrence and survival outcome in hepatocellular carcinoma	4
Comprehensive analysis of distal-less homeobox family gene expression in colon cancer	4
Microbiota regulation in constipation and colorectal cancer	4
KIFC3 promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling	4
Prospect of lenvatinib for unresectable hepatocellular carcinoma in the new era of systemic chemotherapy	4
Nutrition deprivation affects the cytotoxic effect of CD8 T cells in hepatocellular carcinoma	4
Biomarkers for response to immune checkpoint inhibitors in gastrointestinal cancers	4
Prognostic value of modified Lauren classification in gastric cancer	4
Multinational survey on the preferred approach to management of Barrett’s esophagus in the Asia-Pacific region	4
Progress in the treatment of advanced hepatocellular carcinoma with immune combination therapy	4
Gastrointestinal function testing model using a new laryngopharyngeal pH probe (Restech) in patients after Ivor-Lewis esophagectomy	4
Regulatory role of the transforming growth factor-β signaling pathway in the drug resistance of gastrointestinal cancers	4
Real-time fluorescence image-guided gastrointestinal oncologic surgery: Towards a new era	4
Prognostic impact of tumor deposits on overall survival in colorectal cancer: Based on Surveillance, Epidemiology, and End Results database	4
Correlation between immune-related adverse events and long-term outcomes in pembrolizumab-treated patients with unresectable hepatocellular carcinoma: A retrospective study	4
MiR-30e-3p inhibits gastric cancer development by negatively regulating THO complex 2 and PI3K/AKT/mTOR signaling	4
Development of a model based on the age-adjusted Charlson comorbidity index to predict survival for resected perihilar cholangiocarcinoma	4
Xiaojianzhong decoction prevents gastric precancerous lesions in rats by inhibiting autophagy and glycolysis in gastric mucosal cells	4
Exosomes in metastasis of colorectal cancers: Friends or foes?	4
Conservative management of malignant gastric outlet obstruction syndrome-evidence based evaluation of endoscopic ultrasound-guided gastroentero-anastomosis	4
Fibrinogen-to-albumin ratio predicts overall survival of hepatocellular carcinoma	4
Role of tumor-associated macrophages in common digestive system malignant tumors	4
Biofeedback therapy combined with Baduanjin on quality of life and gastrointestinal hormone level in patients with colorectal cancer	4
Diabetes mellitus contribution to the remodeling of the tumor microenvironment in gastric cancer	4
Internal hemorrhoid harboring adenocarcinoma: A case report	4
EFNA1in gastrointestinal cancer: Expression, regulation and clinical significance	4
Proteomic signatures of infiltrative gastric cancer by proteomic and bioinformatic analysis	4
Liver tumors in children with chronic liver diseases	4
Survival outcomes and prognostic indicators for gastric cancer patients with positive peritoneal wash cytology but no peritoneal metastasis after radical gastrectomy	4
Evaluation of polygenic risk score for risk prediction of gastric cancer	4
Diffuse reduction of spleen density is a novel prognostic marker for intrahepatic cholangiocarcinoma after curative resection	4
Influence of the heat irrigating effect of radiofrequency ablation on regional liver tissue in Bama miniature pigs	4
Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathway	4
Efficacy of neoadjuvant chemotherapy for initially resectable colorectal liver metastases: A retrospective cohort study	4
Potential of six-transmembrane epithelial antigen of the prostate 4 as a prognostic marker for colorectal cancer	4
Implication of gut microbiome in immunotherapy for colorectal cancer	4