World Journal of Gastrointestinal Oncology

Article	Citations
Gastrointestinal neuroendocrine tumors in 2020	109
Early stage colon cancer: Current treatment standards, evolving paradigms, and future directions	57
Changes in extracellular matrix in different stages of colorectal cancer and their effects on proliferation of cancer cells	37
Young-onset colorectal cancer: A review	35
Identification of an immune-related gene-based signature to predict prognosis of patients with gastric cancer	32
Liquid biopsy in cholangiocarcinoma: Current status and future perspectives	29
Colorectal cancer screening in the COVID-19 era	28
Gastric neuroendocrine tumor: A practical literature review	25
LINC00511 promotes gastric cancer cell growth by acting as a ceRNA	24
Hepatic Hemangioendothelioma: An update	22
Nanotechnology and pancreatic cancer management: State of the art and further perspectives	22
Comparison of open and closed hyperthermic intraperitoneal chemotherapy: Results from the United States hyperthermic intraperitoneal chemotherapy collaborative	21
Propofol induces ferroptosis and inhibits malignant phenotypes of gastric cancer cells by regulating miR-125b-5p/STAT3 axis	21
Synergistic anti-liver cancer effects of curcumin and total ginsenosides	20
Neoadjuvant chemotherapy for colorectal liver metastases: A contemporary review of the literature	20
Early-onset colorectal cancer: Current insights and future directions	20
Achievement of complete response to nivolumab in a patient with advanced sarcomatoid hepatocellular carcinoma: A case report	19
Structure and function of Septin 9 and its role in human malignant tumors	18
Diagnostic value of four serum exosome microRNAs panel for the detection of colorectal cancer	18
Gastric cancer with peritoneal metastases: Efficiency of standard treatment methods	18
Radiomics in hepatocellular carcinoma: A state-of-the-art review	17
Inflammatory bowel disease-related colorectal cancer: Past, present and future perspectives	17
Low ligation has a lower anastomotic leakage rate after rectal cancer surgery	17
Helicobacter pylori, gastric microbiota and gastric cancer relationship: Unrolling the tangle	17
Helicobacter pylori infection and other bacteria in pancreatic cancer and autoimmune pancreatitis	17

Colorectal cancer carcinogenesis: From bench to bedside	17
Prognostic significance of KIF23 expression in gastric cancer	16
Diverse roles of FOXO family members in gastric cancer	16
Overgrowth of Lactobacillus in gastric cancer	16
Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway	16
Association of Helicobacter pylori infection with colorectal polyps and malignancy in China	16
Colorectal cancer in Arab world: A systematic review	16
Efficacy and safety of anti-PD-1/anti-PD-L1 antibody therapy in treatment of advanced gastric cancer or gastroesophageal junction cancer: A meta-analysis	15
Prognostic significance of systemic immune-inflammation index in patients with intrahepatic cholangiocarcinoma undergoing hepatic resection	15
Clinical and pathological characteristics and prognosis of 132 cases of rectal neuroendocrine tumors	15
Regulatory RNAs, microRNA, long-non coding RNA and circular RNA roles in colorectal cancer stem cells	15
BRAFV600E mutant colorectal cancer cells mediate local immunosuppressive microenvironment through exosomal long noncoding RNAs	15
Gallbladder cancer: Historical treatment and new management options	14
Unique situation of hepatocellular carcinoma in Egypt: A review of epidemiology and control measures	14
Development of artificial intelligence technology in diagnosis, treatment, and prognosis of colorectal cancer	13
Minimally invasive surgical treatment of intrahepatic cholangiocarcinoma: A systematic review	13
Early diagnosis and therapeutic strategies for hepatocellular carcinoma: From bench to bedside	13
Programmed death 1, ligand 1 and 2 correlated genes and their association with mutation, immune infiltration and clinical outcomes of hepatocellular carcinoma	13
Pancreatic intraductal papillary mucinous neoplasms: Current diagnosis and management	13
Gastric epithelial histology and precancerous conditions	13
Decreased expression of the long non-coding RNA HOXD-AS2 promotes gastric cancer progression by targeting HOXD8 and activating PI3K/Akt signaling pathway	13
Endoscopic or percutaneous biliary drainage in hilar cholangiocarcinoma: When and how?	13
Microbiome and colorectal carcinogenesis: Linked mechanisms and racial differences	13
Highly accurate colorectal cancer prediction model based on Raman spectroscopy using patient serum	13
Oncological outcomes and predictors of radiofrequency ablation of colorectal cancer liver metastases	13
Sorafenib combined with embolization plus hepatic arterial infusion chemotherapy for inoperable hepatocellular carcinoma	13
Role of prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer	12
Nutritional therapy for hepatocellular carcinoma	12
Increased KIF21B expression is a potential prognostic biomarker in hepatocellular carcinoma	12
Immunotherapy in liver transplantation for hepatocellular carcinoma: Pros and cons	11
Immune checkpoint inhibitor-mediated colitis in gastrointestinal malignancies and inflammatory bowel disease	11
Notch signalling pathway in development of cholangiocarcinoma	11
Myeloid-derived suppressor cells in gastrointestinal cancers: A systemic review	11
LncRNA C9orf139 can regulate the growth of pancreatic cancer by mediating the miR-663a/Sox12 axis	11
Molecular determinants of response to 5-fluorouracil-based chemotherapy in colorectal cancer: The undisputable role of micro-ribonucleic acids	11
Biomarkers for hepatocellular carcinoma based on body fluids and feces	11
Nomogram using F-18 fluorodeoxyglucose positron emission tomography/computed tomography for preoperative prediction of lymph node metastasis in gastric cancer	11
Diagnostic performance of narrow-band imaging international colorectal endoscopic and Japanese narrow-band imaging expert team classification systems for colorectal cancer and precancerous lesions	11
Application of the woodchuck animal model for the treatment of hepatitis B virus-induced liver cancer	11
Outcomes of curative esophageal cancer surgery in elderly: A meta-analysis	10
Atezolizumab plus bevacizumab versus sorafenib or atezolizumab alone for unresectable hepatocellular carcinoma: A systematic review	10
Characterization and strong risk association of TLR2 del -196 to -174 polymorphism and Helicobacter pylori and their influence on mRNA expression in gastric cancer	10
Recent update on comprehensive therapy for advanced hepatocellular carcinoma	10
Anatomical vs nonanatomical liver resection for solitary hepatocellular carcinoma: A systematic review and meta-analysis	10
Efficacy of mesenchymal stem cells in the treatment of gastrointestinal malignancies	10
Non-surgical treatment of hilar cholangiocarcinoma	10
Neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 as prognostic markers for advanced pancreatic cancer patients receiving first-line chemotherapy	10
Claudin 18.2 is a potential therapeutic target for zolbetuximab in pancreatic ductal adenocarcinoma	10
Identification of a nine-gene prognostic signature for gastric carcinoma using integrated bioinformatics analyses	10
Crosstalk between gut microbiota and COVID-19 impacts pancreatic cancer progression	10

Management of obstructive colon cancer: Current status, obstacles, and future directions	10
Clinicopathological characteristics and prognosis of 77 cases with type 3 gastric neuroendocrine tumours	10
Lateral pelvic lymph nodes for rectal cancer: A review of diagnosis and management	10
Review of incidence and outcomes of treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis	10
Free fatty acids receptors 2 and 3 control cell proliferation by regulating cellular glucose uptake	10
Mesenchymal stem cell-derived exosomes for gastrointestinal cancer	10
Expression and significance of miR-654-5p and miR-376b-3p in patients with colon cancer	10
Influence of primary tumor location and resection on survival in metastatic colorectal cancer	10
Prognostic significance of Borrmann type combined with vessel invasion status in advanced gastric cancer	10
Prognostic impact of at least 12 lymph nodes after neoadjuvant therapy in rectal cancer: A meta-analysis	10
Robotic- vs laparoscopic-assisted proctectomy for locally advanced rectal cancer based on propensity score matching: Short-term outcomes at a colorectal center in China	9
Perineural invasion as a prognostic factor in patients with stage I-III rectal cancer – 5-year follow up	9
Total neoadjuvant therapy vs standard therapy of locally advanced rectal cancer with high-risk factors for failure	9
Current controversies and advances in the management of pancreatic adenocarcinoma	9
Role of exosomal long non-coding RNAs in colorectal cancer	9
Molecular testing for colorectal cancer: Clinical applications	9
Small bowel adenocarcinoma: An overview	9
Thermal ablation and immunotherapy for hepatocellular carcinoma: Recent advances and future directions	9
Bromodomain and extra-terminal inhibitors emerge as potential therapeutic avenues for gastrointestinal cancers	9
Current role of hepatopancreatoduodenectomy for the management of gallbladder cancer and extrahepatic cholangiocarcinoma: A systematic review	9
Role of autophagy in cholangiocarcinoma: An autophagy-based treatment strategy	9
Neoantigen vaccine: An emerging immunotherapy for hepatocellular carcinoma	9
Circulating cytokines and outcome in metastatic colorectal cancer patients treated with regorafenib	9
Real-world evidence on adjuvant chemotherapy in older adults with stage II/III colon cancer	9
Primary tumor location and survival in colorectal cancer: A retrospective cohort study	9
Endoscopic mucosal resection vs endoscopic submucosal dissection for superficial non-ampullary duodenal tumors	9
Digestive cancer incidence and mortality among young adults worldwide in 2020: A population-based study	9
Endoscopic ultrasound-guided ablation of solid pancreatic lesions: A systematic review of early outcomes with pooled analysis	8
Gut microbiome in non-alcoholic fatty liver disease associated hepatocellular carcinoma: Current knowledge and potential for therapeutics	8
Outcomes of neoadjuvant chemoradiotherapy followed by radical resection for T4 colorectal cancer	8
Recent advances in targeted therapy for pancreatic adenocarcinoma	8
Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways	8
Endoscopic ultrasound assessment and tissue acquisition of mediastinal and abdominal lymph nodes	8
Multimodal treatment in oligometastatic gastric cancer	8
Gastric cancer: An epigenetic view	8
Clinical characteristics and outcome of primary hepatic neuroendocrine tumors after comprehensive therapy	8
Comparison of hyperthermic intraperitoneal chemotherapy regimens for treatment of peritoneal-metastasized colorectal cancer	8
Fibrolamellar hepatocellular carcinoma: A rare but unpleasant event	8
Glutamine deprivation impairs function of infiltrating CD8+ T cells in hepatocellular carcinoma by inducing mitochondrial damage and apoptosis	8
MicroRNA expression in inflammatory bowel disease-associated colorectal cancer	8
Maspin subcellular expression in wild-type and mutant TP53 gastric cancers	8
Advances in postoperative adjuvant therapy for primary liver cancer	8
Primary malignant vascular tumors of the liver in children: Angiosarcoma and epithelioid hemangioendothelioma	8
Poorly cohesive cells gastric carcinoma including signet-ring cell cancer: Updated review of definition, classification and therapeutic management	8
Molecular regulatory mechanism of ferroptosis and its role in gastrointestinal oncology: Progress and updates	8
Pathological, molecular, and clinical characteristics of cholangiocarcinoma: A comprehensive review	8
Familial adenomatous polyposis and changes in the gut microbiota: New insights into colorectal cancer carcinogenesis	7
Comparison of tumor regression grading systems for locally advanced gastric adenocarcinoma after neoadjuvant chemotherapy	7
Association between intestinal neoplasms and celiac disease: A review	7
Novel perspective in pancreatic cancer therapy: Targeting ferroptosis pathway	7
Liquid biopsy approach to pancreatic cancer	7
Exosomes as potential diagnosis and treatment for liver cancer	7
How the COVID-19 pandemic has affected the colorectal cancer screening in Italy: A minireview	7
Hypoxia and its impact on the tumour microenvironment of gastroesophageal cancers	7
One size does not fit all for pancreatic cancers: A review on rare histologies and therapeutic approaches	7
FOLFOXIRI vs FOLFIRINOX as first-line chemotherapy in patients with advanced pancreatic cancer: A population-based cohort study	7
Plexiform fibromyxoma: Review of rare mesenchymal gastric neoplasm and its differential diagnosis	7
Management of single pulmonary metastases from colorectal cancer: State of the art	7
Neutrophile-to-lymphocyte, lymphocyte-to-monocyte, and platelet-to-lymphocyte ratios as prognostic and response biomarkers for resectable locally advanced gastric cancer	7
Blood exosomal micro ribonucleic acid profiling reveals the complexity of hepatocellular carcinoma and identifies potential biomarkers for differential diagnosis	7
Radiofrequency ablation in the management of primary hepatic and biliary tumors	6
Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model	6
Clinical management for malignant afferent loop obstruction	6
Immunotherapy for nonalcoholic fatty liver disease-related hepatocellular carcinoma: Lights and shadows	6
Current status of non-surgical treatment of locally advanced pancreatic cancer	6
Methylation changes at the GNAS imprinted locus in pancreatic cystic neoplasms are important for the diagnosis of malignant cysts	6
Robotic resection of liver focal nodal hyperplasia guided by indocyanine green fluorescence imaging: A preliminary analysis of 23 cases	6
Is the combination of immunotherapy with conventional chemotherapy the key to increase the efficacy of colorectal cancer treatment?	6
Extracellular vesicles: General features and usefulness in diagnosis and therapeutic management of colorectal cancer	6
Characterization of metabolic landscape in hepatocellular carcinoma	6
Vasoactive intestinal peptide secreting tumour: An overview	6
Clinical diagnosis and management of pancreatic mucinous cystadenoma and cystadenocarcinoma: Single-center experience with 82 patients	6
Comparison of prognostic factors in different age groups and prognostic significance of neutrophil-lymphocyte ratio in patients with gastric cancer	6
Latest therapeutic target for gastric cancer: Anthrax toxin receptor 1	6
Surgical intervention for malignant bowel obstruction caused by gastrointestinal malignancies	6
Clinical significance of molecular subtypes of gastrointestinal tract adenocarcinoma	6
Same day yttrium-90 radioembolization with single photon emission computed tomography/computed tomography: An opportunity to improve care during the COVID-19 pandemic and beyond	6
Update on the management of the gastrointestinal effects of radiation	6
Cryptotanshinone inhibits cytotoxin-associated gene A-associated development of gastric cancer and mucosal erosions	6
Relation between skeletal muscle volume and prognosis in rectal cancer patients undergoing neoadjuvant therapy	6

Can dietary flavonoids be useful in the personalized treatment of colorectal cancer?	6
Scoping out the future: The application of artificial intelligence to gastrointestinal endoscopy	6
What is the best surgical procedure of transverse colon cancer? An evidence map and minireview	6
Immune evasion mechanisms and therapeutic strategies in gastric cancer	6
Timing of surgery after neoadjuvant chemoradiotherapy affects oncologic outcomes in patients with esophageal cancer	6
Changing trends of clinicopathologic features and survival duration after surgery for gastric cancer in Northeast China	6
Engineering nanotheranostic strategies for liver cancer	6
Screening strategy for gastrointestinal and hepatopancreatobiliary cancers in cystic fibrosis	6
Genome-wide CRISPR-Cas9 screening identifies that hypoxia-inducible factor-1a-induced CBX8 transcription promotes pancreatic cancer progression via IRS1/AKT axis	5
Effect of oncometabolic surgery on gastric cancer: The remission of hypertension, type 2 diabetes mellitus, and beyond	5
Role of mammalian target of rapamycin complex 2 in primary and secondary liver cancer	5
Effects ofHelicobacter pyloriinfection in gastrointestinal tract malignant diseases: From the oral cavity to rectum	5
Application of metabolomics in clinical and laboratory gastrointestinal oncology	5
Risk factors, prognostic predictors, and nomograms for pancreatic cancer patients with initially diagnosed synchronous liver metastasis	5
Contemporary treatment approaches for metastatic colorectal cancer driven by BRAF V600 mutations	5
Endoscopic radiofrequency ablation for malignant biliary obstruction	5
Role of autophagy in gastric carcinogenesis	5
B7 homologue 3 as a prognostic biomarker and potential therapeutic target in gastrointestinal tumors	5
Shuyu pills inhibit immune escape and enhance chemosensitization in hepatocellular carcinoma	5
Should we resect colorectal cancer in patients over the age of 85?	5
Angiogenesis in gastrointestinal stromal tumors: From bench to bedside	5
Macrophages play a role in inflammatory transformation of colorectal cancer	5
Cutaneous metastases of pancreatic carcinoma to the labia majora: A case report and review of literature	5
Interleukin-1 receptor antagonist enhances chemosensitivity to fluorouracil in treatment of Kras mutant colon cancer	5
Combined treatments in hepatocellular carcinoma: Time to put them in the guidelines?	5
Outcomes of curative liver resection for hepatocellular carcinoma in patients with cirrhosis	5
Gut microbiota and immune system in liver cancer: Promising therapeutic implication from development to treatment	5
Characterizing the patient experience during neoadjuvant therapy for pancreatic ductal adenocarcinoma: A qualitative study	5
Rare common bile duct metastasis of breast cancer: A case report and literature review	5
Effects of dietary zinc deficiency on esophageal squamous cell proliferation and the mechanisms involved	5
Sporadic fundic gland polyps with dysplasia or carcinoma: Clinical and endoscopic characteristics	5
Solid extraintestinal malignancies in patients with inflammatory bowel disease	5
Interleukin-34 promotes the proliferation and epithelial-mesenchymal transition of gastric cancer cells	5
High expression of protein phosphatase 2 regulatory subunit B'' alpha predicts poor outcome in hepatocellular carcinoma patients after liver transplantation	5
Clinical significance of SQSTM1/P62 and nuclear factor-κB expression in pancreatic carcinoma	5
Laparoscopic liver resection for colorectal liver metastases — short- and long-term outcomes: A systematic review	5
Role of three-dimensional printing and artificial intelligence in the management of hepatocellular carcinoma: Challenges and opportunities	5
Angiotensin-converting enzyme 2 connects COVID-19 with cancer and cancer immunotherapy	5
Conservative management of malignant gastric outlet obstruction syndrome-evidence based evaluation of endoscopic ultrasound-guided gastroentero-anastomosis	4
Emerging role of caldesmon in cancer: A potential biomarker for colorectal cancer and other cancers	4
Computed tomography-based radiomic to predict resectability in locally advanced pancreatic cancer treated with chemotherapy and radiotherapy	4
Trimodality treatment in gastric and gastroesophageal junction cancers: Current approach and future perspectives	4
Potential of six-transmembrane epithelial antigen of the prostate 4 as a prognostic marker for colorectal cancer	4
Internal hemorrhoid harboring adenocarcinoma: A case report	4
Perineural invasion of hilar cholangiocarcinoma in Chinese population: One center’s experience	4
Fibrin sealant for esophageal anastomosis: A phase II study	4
Clinical implications of interleukins-31, 32, and 33 in gastric cancer	4
Sarcopenia in pancreatic cancer: Effect on patient outcomes	4
Survival effect of probiotics in a rat model of colorectal cancer treated with capecitabine	4
Research progress of integrated traditional Chinese and Western medicine in the treatment of advanced gastric cancer	4
Berberine retarded the growth of gastric cancer xenograft tumors by targeting hepatocyte nuclear factor 4α	4
Pancreatic neuroendocrine tumors G3 and pancreatic neuroendocrine carcinomas: differences in basic biology and treatment	4
Proteasome regulators in pancreatic cancer	4
Increased CD4/CD8 Lymphocyte ratio predicts favourable neoadjuvant treatment response in gastric cancer: A prospective pilot study	4
Sex as an effect modifier in the association between alcohol intake and gastric cancer risk	4
New frontiers in liver ultrasound: From mono to multi parametricity	4
Diabetes mellitus contribution to the remodeling of the tumor microenvironment in gastric cancer	4
Practical considerations for colorectal cancer screening in older adults	4
Potential utility of liquid biopsies in the management of patients with biliary tract cancers: A review	4
Comparison of survival between adolescent and young adult vs older patients with hepatocellular carcinoma	4
Low body mass index is an independent predictor of poor long-term prognosis among patients with resectable gastric cancer	4
Prognostic value of claudin 18.2 expression in gastric adenocarcinoma	4
Serum vascular endothelial growth factor as a tumor marker for hepatocellular carcinoma in hepatitis C virus-related cirrhotic patients	4
Does the addition of Braun anastomosis to Billroth II reconstruction on laparoscopic-assisted distal gastrectomy benefit patients?	4
Pancreatic head vs pancreatic body/tail cancer: Are they different?	4
VCAN, expressed highly in hepatitis B virus-induced hepatocellular carcinoma, is a potential biomarker for immune checkpoint inhibitors	4
Efficacy of neoadjuvant chemotherapy for initially resectable colorectal liver metastases: A retrospective cohort study	4
Efficacy and safety of endoscopic resection in treatment of small gastric stromal tumors: A state-of-the-art review	4
γ-glutamyl transferase-to-platelet ratio based nomogram predicting overall survival of gallbladder carcinoma	4
Cuproptosis-related long non-coding RNAs model that effectively predicts prognosis in hepatocellular carcinoma	4
Neoadjuvant therapy in resectable pancreatic cancer: A promising curative method to improve prognosis	4
Stereotactic radiotherapy for intrahepatic cholangiocarcinoma	4
Prospect of lenvatinib for unresectable hepatocellular carcinoma in the new era of systemic chemotherapy	4
Molecular-targeted therapy toward precision medicine for gastrointestinal caner: Current progress and challenges	4
Neoadjuvant chemotherapy without radiation as a potential alternative treatment for locally advanced rectal cancer: A meta-analysis	4
Crohn’s disease with infliximab treatment complicated by rapidly progressing colorectal cancer: A case report	4
Endoscopic papillectomy for ampullary adenomatous lesions: A literature review	4
Yield of surgery in solid pseudopapillary neoplasms of the pancreas: A case series and literature review	4
Intratumour microbiome of pancreatic cancer	4
Cell-free DNA liquid biopsy for early detection of gastrointestinal cancers: A systematic review	3
Clinical outcomes of patients with duodenal adenocarcinoma and intestinal-type papilla of Vater adenocarcinoma	3
Gut microbiome and pancreatic cancer cachexia: An evolving relationship	3
Prognostic value of modified Lauren classification in gastric cancer	3
Overexpression of ELL-associated factor 2 suppresses invasion, migration, and angiogenesis in colorectal cancer	3
Multinational survey on the preferred approach to management of Barrett’s esophagus in the Asia-Pacific region	3
Lipid metabolism of hepatocellular carcinoma impacts targeted therapy and immunotherapy	3
Endoscopic ultrasound-guided fiducial marker placement for neoadjuvant chemoradiation therapy for resectable pancreatic cancer	3
Minimally invasive vs open pancreatectomy for nonfunctioning pancreatic neuroendocrine tumors	3
Comprehensive molecular characterization and identification of prognostic signature in stomach adenocarcinoma on the basis of energy-metabolism-related genes	3
Current guidelines in the surgical management of hereditary colorectal cancers	3
Anatomic resection improved the long-term outcome of hepatocellular carcinoma patients with microvascular invasion: A prospective cohort study	3
Immunotherapy in biliary tract cancers: Current evidence and future perspectives	3
Digital single-operator cholangioscopy for biliary stricture after cadaveric liver transplantation	3
Clinicopathological characterization of ten patients with primary malignant melanoma of the esophagus and literature review	3
Nutrition deprivation affects the cytotoxic effect of CD8 T cells in hepatocellular carcinoma	3