World Journal of Stem Cells

Article	Citations
Application and prospects of high-throughput screening for in vitro neurogenesis	57
Stem cells and pain	53
Combination of mesenchymal stem cells and three-dimensional collagen scaffold preserves ventricular remodeling in rat myocardial infarction model	50
Wharton’s jelly mesenchymal stem cells: Future regenerative medicine for clinical applications in mitigation of radiation injury	43
Regulation of the mesenchymal stem cell fate by interleukin-17: Implications in osteogenic differentiation	38
Safety and efficiency of Wharton’s Jelly-derived mesenchymal stem cell administration in patients with traumatic brain injury: First results of a phase I study	37
Dental mesenchymal stromal/stem cells in different microenvironments— implications in regenerative therapy	35
Bone marrow mesenchymal stem cell therapy regulates gut microbiota to improve post-stroke neurological function recovery in rats	35
Emerging role of mesenchymal stem cell-derived exosomes in the repair of acute kidney injury	34
Recombinant human thrombopoietin safety and efficacy in pediatric allogeneic hematopoietic stem cell transplantation: A cohort study	33
Central nervous system tumors and three-dimensional cell biology: Current and future perspectives in modeling	29
Intercellular mitochondrial transfer as a means of revitalizing injured glomerular endothelial cells	29
MicroRNA-584-5p/RUNX family transcription factor 2 axis mediates hypoxia-induced osteogenic differentiation of periosteal stem cells	29
Human retinal secretome: A cross-link between mesenchymal and retinal cells	27
Effects of exosomes from mesenchymal stem cells on functional recovery of a patient with total radial nerve injury: A pilot study	27
Clinical trials using dental stem cells: 2022 update	27
Harnessing and honing mesenchymal stem/stromal cells for the amelioration of graft-versus-host disease	26
Biological scaffold as potential platforms for stem cells: Current development and applications in wound healing	25
Priming strategies for controlling stem cell fate: Applications and challenges in dental tissue regeneration	25
Induced pluripotent stem cells as suitable sensors for fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome	23
Multiroute administration of Wharton’s jelly mesenchymal stem cells in chronic complete spinal cord injury: A phase I safety and feasibility study	22
Interferon-γ priming enhances the therapeutic effects of menstrual blood-derived stromal cells in a mouse liver ischemia-reperfusion model	22
Mechanisms of analgesic effect of mesenchymal stem cells in osteoarthritis pain	22
Collagen III combined with autologous adipose-derived mesenchymal stem cells accelerates burn wound healing in a rat model	22
Mesenchymal stem cell-derived extracellular vesicles: Pioneering the next generation of biomedical applications	21

Gamma-aminobutyric acid enhances miR-21-5p loading into adipose-derived stem cell extracellular vesicles to alleviate myocardial ischemia-reperfusion injury via TXNIP regulation	21
Fibro-adipogenic progenitors prevent skeletal muscle degeneration at acute phase upon tendon rupture in a murine tibialis anterior tenotomy model	21
Sinomenine promotes differentiation of induced pluripotent stem cells into immature dendritic cells with high induction of immune tolerance	20
MiR-21-5p-enriched exosomes from hiPSC-derived cardiomyocytes exhibit superior cardiac repair efficacy compared to hiPSC-derived exosomes in a murine MI model	20
Gut microbiota modulating intestinal stem cell differentiation	20
Current status and prospects of basic research and clinical application of mesenchymal stem cells in acute respiratory distress syndrome	19
Tumor necrosis factor-α inhibition restores matrix formation by human adipose-derived stem cells in the late stage of chondrogenic differentiation	19
Extracellular vesicles: Emerged as a promising strategy for regenerative medicine	19
Patient-derived induced pluripotent stem cells with a MERTK mutation exhibit cell junction abnormalities and aberrant cellular differentiation potential	18
Considerations for the clinical use of stem cells in genitourinary regenerative medicine	18
Treatment of syringomyelia using uncultured umbilical cord mesenchymal stem cells: A case report and review of literature	18
Mesenchymal stem cell exosomes enhance the development of hair follicle to ameliorate androgenetic alopecia	17
Effects of living and metabolically inactive mesenchymal stromal cells and their derivatives on monocytes and macrophages	17
Exosomal miR-137-3p targets UBE3C to activate STAT3, promoting migration and differentiation into endometrial epithelial cell of human umbilical cord mesenchymal stem cells under hypoxia	17
Understanding and controlling the variables for advanced cell therapy	17
Mesenchymal stem/stromal cells as adjuvant therapy in COVID-19-associated acute lung injury and cytokine storm: Importance of cell identification	16
Application of adipose-derived stem cells in treating fibrosis	16
MKK7-mediated phosphorylation of JNKs regulates the proliferation and apoptosis of human spermatogonial stem cells	16
Repetitive administration of cultured human CD34+ cells improve adenine-induced kidney injury in mice	15
Banking of perinatal mesenchymal stem/stromal cells for stem cell-based personalized medicine over lifetime: Matters arising	15
ARPE-19 conditioned medium promotes neural differentiation of adipose-derived mesenchymal stem cells	15
Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications	15
Potential of ginsenoside Rg1 to treat aplastic anemia via mitogen activated protein kinase pathway in cyclophosphamide-induced myelosuppression mouse model	14
Innovative hydrogel delivery of bone marrow stromal cell-derived exosomes for enhanced bone healing	13
Refining adipose-derived stem cell isolation for optimal regenerative therapy	13
Barriers to mesenchymal stromal cells for low back pain	13
Effects of different concentrations of nicotinamide on hematopoietic stem cells cultured in vitro	13
Additional comments on extracellular vesicles derived from mesenchymal stem cells mediate extracellular matrix remodeling in osteoarthritis	12
Recent progress in hair follicle stem cell markers and their regulatory roles	12
O-linked β-N-acetylglucosaminylation may be a key regulatory factor in promoting osteogenic differentiation of bone marrow mesenchymal stromal cells	12
Gossypol acetic acid regulates leukemia stem cells by degrading LRPPRC via inhibiting IL-6/JAK1/STAT3 signaling or resulting mitochondrial dysfunction	12
Inhibition of glutathione metabolism can limit the development of pancreatic cancer	12
Cell-free extracts from human fat tissue attenuate ischemic injury in cardiomyocytes in a murine model	12
Preliminary study on the preparation of lyophilized acellular nerve scaffold complexes from rabbit sciatic nerves with human umbilical cord mesenchymal stem cells	12
Induced pluripotent stem cell-derived mesenchymal stem cells for modeling and treating metabolic associated fatty liver disease and metabolic associated steatohepatitis: Challenges and opportunities	12
Therapeutic effects of menstrual blood-derived endometrial stem cells on mouse models of streptozotocin-induced type 1 diabetes	12
Delineating the glioblastoma stemness by genes involved in cytoskeletal rearrangements and metabolic alterations	12
Adipokines regulate mesenchymal stem cell osteogenic differentiation	11
Anti-fibrotic effect of adipose-derived stem cells on fibrotic scars	11
Crosstalk between Wnt and bone morphogenetic protein signaling during osteogenic differentiation	11
Advances of nanotechnology applied to cancer stem cells	11
Molecular mechanism of therapeutic approaches for human gastric cancer stem cells	11
Quercetin ameliorates oxidative stress-induced senescence in rat nucleus pulposus-derived mesenchymal stem cells via the miR-34a-5p/SIRT1 axis	11
Exosomes derived from inflammatory myoblasts promote M1 polarization and break the balance of myoblast proliferation/differentiation	10
Overexpression of GATA binding protein 4 and myocyte enhancer factor 2C induces differentiation of mesenchymal stem cells into cardiac-like cells	10
Circular RNAs inducing the osteogenic differentiation of dental mesenchymal stem cells via microRNA sponging	10
Immortalization of epidural fat-derived mesenchymal stem cells: In vitro characterization and adipocyte differentiation potential	10
Innovative mesenchymal stem cell treatments for fatty liver disease	10
Bone marrow mesenchymal stem cell treatment improves post-stroke cerebral function recovery by regulating gut microbiota in rats	10
High glucose microenvironment and human mesenchymal stem cell behavior	10

Mesenchymal stem cells for enhancing biological healing after meniscal injuries	10
Safety and efficiency of Wharton’s Jelly-derived mesenchymal stem cell administration in patients with traumatic brain injury: First results of a phase I study	10
Strategies to improve the effect of mesenchymal stem cell therapy on inflammatory bowel disease	10
Application of dental stem cells in three-dimensional tissue regeneration	10
Strategies to improve regenerative potential of mesenchymal stem cells	9
Preliminary evidence of renal function improvement in chronic progressive kidney disease using autologous CD34+ cell therapy: A clinical trial	9
Human dental pulp stem/stromal cells in clinical practice	9
Stimulating factors for regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells	9
How to enhance the ability of mesenchymal stem cells to alleviate intervertebral disc degeneration	9
Potential plausible role of Wharton’s jelly mesenchymal stem cells for diabetic bone regeneration	9
MiR-126 regulates the effect of mesenchymal stem cell vascular repair on carotid atherosclerosis through MAPK/ERK signaling pathway	9
Therapeutic applications of adipose-derived stromal vascular fractions in osteoarthritis	9
Mesenchymal stem cells and COVID-19: What they do and what they can do	9
Stem cell transplantation in cerebrovascular accidents: A global bibliometric analysis (2000-2023)	9
Downregulation of miRNA-21 and cancer stem cells after chemotherapy results in better outcome in breast cancer patients	9
Self-assembly of differentiated dental pulp stem cells facilitates spheroid human dental organoid formation and prevascularization	9
Synergism of calycosin and bone marrow-derived mesenchymal stem cells to combat podocyte apoptosis to alleviate adriamycin-induced focal segmental glomerulosclerosis	9
Stem cell therapy: A promising therapeutic approach for skeletal muscle atrophy	9
Skinny people serum factors promote the differentiation of multipotent stem cells into brown adipose tissue	8
Dissecting molecular mechanisms underlying ferroptosis in human umbilical cord mesenchymal stem cells: Role of cystathionine γ-lyase/hydrogen sulfide pathway	8
WDR36 inhibits the osteogenic differentiation and migration of periodontal ligament stem cells	8
Constitutive aryl hydrocarbon receptor facilitates the regenerative potential of mouse bone marrow mesenchymal stromal cells	8
Effects of macrophages on the osteogenic differentiation of adipose tissue-derived stem cells in two-dimensional and three-dimensional cocultures	8
SOX transcription factors and glioma stem cells: Choosing between stemness and differentiation	8
Priming strategies for controlling stem cell fate: Applications and challenges in dental tissue regeneration	8
Transcription regulators differentiate mesenchymal stem cells into chondroprogenitors, and their in vivo implantation regenerated the intervertebral disc degeneration	7
Application of mesenchymal stem cell therapy for premature ovarian insufficiency: Recent advances from mechanisms to therapeutics	7
Long noncoding RNAs in mesenchymal stromal/stem cells osteogenic differentiation: Implications in osteoarthritis pathogenesis	7
Umbilical cord mesenchymal stem cell exosomes alleviate necrotizing enterocolitis in neonatal mice by regulating intestinal epithelial cells autophagy	7
Stem cell therapy for intervertebral disc degeneration: Clinical progress with exosomes and gene vectors	7
Mesenchymal stem cell-derived exosomes and the Wnt/β-catenin pathway: Unifying mechanisms of multi-organ regeneration and the path to precision clinical translation	7
Generation of a human haploid neural stem cell line for genome-wide genetic screening	7
Bibliometrics of trends in global research on the roles of stem cells in myocardial fibrosis therapy	7
Advances in human umbilical cord mesenchymal stem cells-derived extracellular vesicles and biomaterial assemblies for endometrial injury treatment	7
Therapeutic potential of urine-derived stem cells in renal regeneration following acute kidney injury: A comparative analysis with mesenchymal stem cells	7
Molecular signaling in cancer stem cells of tongue squamous cell carcinoma: Therapeutic implications and challenges	7
Cyclodextrin host-guest complex to facilitate sinomenine-based osteoporosis therapy	7
Effects of immune cells on mesenchymal stem cells during fracture healing	7
Role of brahma-related gene 1/brahma-associated factor subunits in neural stem/progenitor cells and related neural developmental disorders	7
Stromal vascular fraction: Mechanisms and application in reproductive disorders	7
Translational products of adipose tissue-derived mesenchymal stem cells: Bench to bedside applications	6
Mechanism of adipose-derived mesenchymal stem cell exosomes in the treatment of heart failure	6
Human amniotic fluid stem cell therapy can help regain bladder function in type 2 diabetic rats	6
Application of extracellular vesicles from mesenchymal stem cells promotes hair growth by regulating human dermal cells and follicles	6
Alternative RNA splicing in stem cells and cancer stem cells: Importance of transcript-based expression analysis	6
Exosomes from circ-Astn1-modified adipose-derived mesenchymal stem cells enhance wound healing through miR-138-5p/SIRT1/FOXO1 axis regulation	6
Transplantation of human induced pluripotent stem cell derived keratinocytes accelerates deep second-degree burn wound healing	6
Clinical application prospects and transformation value of dental follicle stem cells in oral and neurological diseases	6
Reveal more mechanisms of precondition mesenchymal stem cells inhibiting inflammation	6
Emergence of the stromal vascular fraction and secretome in regenerative medicine	6
Optimization of adipose tissue-derived mesenchymal stromal cells transplantation for bone marrow repopulation following irradiation	6
Human umbilical cord mesenchymal stem cells ameliorate liver metabolism in diabetic rats with metabolic-associated fatty liver disease	6
X inactive-specific transcript regulates mitochondrial function and neuronal differentiation of stem cells via IGF2BP2/CPT1A axis in models of spinal cord injury	6
Mesenchymal stem cells-extracellular vesicles alleviate pulmonary fibrosis by regulating immunomodulators	6
Stem cell therapy applied for digestive anastomosis: Current state and future perspectives	6
Exosomes derived from microRNA-540-3p overexpressing mesenchymal stem cells promote immune tolerance via the CD74/nuclear factor-kappaB pathway in cardiac allograft	6
Long noncoding ribonucleic acid ENST00000517482 enhances mesenchymal stem cell therapy against acute lung injury	6
Effects of radiation and chemotherapy on adipose stem cells: Implications for use in fat grafting in cancer patients	6
Long non-coding RNA SNHG16 promotes human placenta-derived mesenchymal stem cell proliferation capacity through the PI3K/AKT pathway under hypoxia	6
First-ever stem cell therapy restores insulin independence in type 1 diabetes: A medical milestone	6
Hypoxia and inflammatory factor preconditioning enhances the immunosuppressive properties of human umbilical cord mesenchymal stem cells	6
VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling	6
Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells alleviates myocardial injury by targeting thioredoxin-interacting protein-mediated hypoxia-inducible factor-1α pathway	6
Childhood insulin resistance and neural stem cell dysfunction in psychiatric disorders: Role of de novo lipogenesis and treatment perspectives	6
Efficacy of serum-free cultured human umbilical cord mesenchymal stem cells in the treatment of knee osteoarthritis in mice	5
Multiple roles of mothers against decapentaplegic homolog 4 in tumorigenesis, stem cells, drug resistance, and cancer therapy	5
Culture and identification of neonatal rat brain-derived neural stem cells	5
Human umbilical cord mesenchymal stem cells reduce platelet α-granule release in rats via the AKT/MEK/ERK pathway during acute exposure to high-altitude hypoxia	5
L-arginine from elder human mesenchymal stem cells induces angiogenesis and enhances therapeutic effects on ischemic heart diseases	5
Human umbilical cord mesenchymal stem cell-derived exosomal miR-199a-3p inhibits the MAPK4/NF-κB signaling pathway to relieve osteoarthritis	5
Dual role of extracellular vesicles in neurodegenerative diseases	5
Optimal good manufacturing practice-compliant production of dental follicle stem cell sheet and its application in Sprague-Dawley rat periodontitis	5
Pretreatment can alleviate programmed cell death in mesenchymal stem cells	5
Unveiling the role of hypoxia-inducible factor 2alpha in osteoporosis: Implications for bone health	5
When hematology meets ophthalmology: Cytomegalovirus retinitis in pediatric stem cell recipients	5
Immunomodulatory effects and clinical application of exosomes derived from mesenchymal stem cells	5
Mesenchymal stem cells-derived exosomes alleviate radiation induced pulmonary fibrosis by inhibiting the protein kinase B/nuclear factor kappa B pathway	5
Impact of senescence on the transdifferentiation process of human hepatic progenitor-like cells	5
MKK7-mediated phosphorylation of JNKs regulates the proliferation and apoptosis of human spermatogonial stem cells	5
Obesity and cancer stem cells: Roles in cancer initiation, progression and therapy resistance	5

Sinomenine increases osteogenesis in mice with ovariectomy-induced bone loss by modulating autophagy	5
Integrin beta 3-overexpressing mesenchymal stromal cells display enhanced homing and can reduce atherosclerotic plaque	5
Resilience and challenges: Evaluating the impact of stress conditions on mesenchymal stem cells across different passages	5
Immunomodulation: The next target of mesenchymal stem cell-derived exosomes in the context of ischemic stroke	4
Research progress and challenges in stem cell therapy for diabetic foot: Bibliometric analysis and perspectives	4
Stem cell-derived biofactors fight against coronavirus infection	4
Perspectives on Schwann-like cells derived from bone marrow-mesenchymal stem cells: Advancing peripheral nerve injury therapies	4
ARPE-19 conditioned medium promotes neural differentiation of adipose-derived mesenchymal stem cells	4
Use of priming strategies to advance the clinical application of mesenchymal stromal/stem cell-based therapy	4
Injectable hydrogel made from antler mesenchyme matrix for regenerative wound healing via creating a fetal-like niche	4
Mid-term outcomes of microfragmented adipose tissue plus arthroscopic surgery for knee osteoarthritis: A randomized, active-control, multicenter clinical trial	4
Effect of tandem autologous stem cell transplantation on survival in pediatric patients with high-risk solid tumors in South China	4
Inter-regulatory role of microRNAs in interaction between viruses and stem cells	4
Advanced glycation end productions and tendon stem/progenitor cells in pathogenesis of diabetic tendinopathy	4
Interferon-gamma and tumor necrosis factor-alpha synergistically enhance the immunosuppressive capacity of human umbilical-cord-derived mesenchymal stem cells by increasing PD-L1 expression	4
Stem cell therapy for insulin-dependent diabetes: Are we still on the road?	4
Challenges in the clinical translation of stromal vascular fraction therapy in regenerative medicine	4
Molecular and therapeutic effects of mesenchymal stem cell-derived exosomes on autoimmune diseases	4
Interplay between mesenchymal stem cells and macrophages: Promoting bone tissue repair	3
Non-coding RNAs in adipose-derived stem cell exosomes: Mechanisms, therapeutic potential, and challenges in wound healing	3
ARPE-19 conditioned medium promotes neural differentiation of adipose-derived mesenchymal stem cells	3
Adipose-derived regenerative therapies for the treatment of knee osteoarthritis	3
Human mesenchymal stem cells exhibit altered mitochondrial dynamics and poor survival in high glucose microenvironment	3
Current evidence on potential of adipose derived stem cells to enhance bone regeneration and future projection	3
Human pluripotent stem cell-derived kidney organoids: Current progress and challenges	3
Differences and similarities between mesenchymal stem cell and endothelial progenitor cell immunoregulatory properties against T cells	3
Melatonin-based priming of stem cells to alleviate oxidative stress	3
Role of stem cells-based in facial nerve reanimation: A meta-analysis of histological and neurophysiological outcomes	3
Disagreements in the therapeutic use of mesenchymal stem cell-derived secretome	3
Effects of interleukin-10 treated macrophages on bone marrow mesenchymal stem cells via signal transducer and activator of transcription 3 pathway	3
Overview of nutritional approach in hematopoietic stem cell transplantation: COVID-19 update	3
Exosomal miR-203 from bone marrow stem cells targets the SOCS3/NF-κB pathway to regulate neuroinflammation in temporal lobe epilepsy	3
Microvesicles derived from mesenchymal stem cells inhibit acute respiratory distress syndrome-related pulmonary fibrosis in mouse partly through hepatocyte growth factor	3
Effects of high glucose and severe hypoxia on the biological behavior of mesenchymal stem cells at various passages	3
Soluble factors secreted by human Wharton’s jelly mesenchymal stromal/stem cells exhibit therapeutic radioprotection: A mechanistic study with integrating network biology	3