World Journal of Stem Cells

Article	Citations
Stem cells and pain	70
Combination of mesenchymal stem cells and three-dimensional collagen scaffold preserves ventricular remodeling in rat myocardial infarction model	63
Clinical trials using dental stem cells: 2022 update	43
Intercellular mitochondrial transfer as a means of revitalizing injured glomerular endothelial cells	37
Stem cell-derived neural organoids as platforms to investigate glioblastoma invasion and migration: A systematic review	34
Recombinant human thrombopoietin safety and efficacy in pediatric allogeneic hematopoietic stem cell transplantation: A cohort study	32
Human retinal secretome: A cross-link between mesenchymal and retinal cells	29
Dental mesenchymal stromal/stem cells in different microenvironments— implications in regenerative therapy	29
Application and prospects of high-throughput screening for in vitro neurogenesis	28
Emerging role of mesenchymal stem cell-derived exosomes in the repair of acute kidney injury	26
Insights into mitofusin-2 and endoplasmic reticulum stress regulation in adipose-derived mesenchymal stem cells senescence	25
Effects of exosomes from mesenchymal stem cells on functional recovery of a patient with total radial nerve injury: A pilot study	23
Bone marrow mesenchymal stem cell therapy regulates gut microbiota to improve post-stroke neurological function recovery in rats	23
Wharton’s jelly mesenchymal stem cells: Future regenerative medicine for clinical applications in mitigation of radiation injury	22
MicroRNA-584-5p/RUNX family transcription factor 2 axis mediates hypoxia-induced osteogenic differentiation of periosteal stem cells	22
Harnessing and honing mesenchymal stem/stromal cells for the amelioration of graft-versus-host disease	22
Safety and efficiency of Wharton’s Jelly-derived mesenchymal stem cell administration in patients with traumatic brain injury: First results of a phase I study	22
Collagen III combined with autologous adipose-derived mesenchymal stem cells accelerates burn wound healing in a rat model	21
Mesenchymal stem cell-derived extracellular vesicles: Pioneering the next generation of biomedical applications	21
Fibro-adipogenic progenitors prevent skeletal muscle degeneration at acute phase upon tendon rupture in a murine tibialis anterior tenotomy model	21
Gut microbiota modulating intestinal stem cell differentiation	20
Comparison of therapeutic potential of macrophage- or mesenchymal stem cell-derived exosomes in pancreatic cancer: An updated review	20
Sinomenine promotes differentiation of induced pluripotent stem cells into immature dendritic cells with high induction of immune tolerance	18
Post-translational modifications in osteogenic differentiation of oral-derived stem cells: Mechanisms and clinical implications	18
Exosomal delivery of GrpE-like 1 from synovial mesenchymal stem cells activates PINK1-mediated mitophagy for cartilage repair in osteoarthritis	17

MiR-21-5p-enriched exosomes from hiPSC-derived cardiomyocytes exhibit superior cardiac repair efficacy compared to hiPSC-derived exosomes in a murine MI model	17
Mechanisms of analgesic effect of mesenchymal stem cells in osteoarthritis pain	17
Gamma-aminobutyric acid enhances miR-21-5p loading into adipose-derived stem cell extracellular vesicles to alleviate myocardial ischemia-reperfusion injury via TXNIP regulation	17
Interferon-γ priming enhances the therapeutic effects of menstrual blood-derived stromal cells in a mouse liver ischemia-reperfusion model	17
Multiroute administration of Wharton’s jelly mesenchymal stem cells in chronic complete spinal cord injury: A phase I safety and feasibility study	16
Biological scaffold as potential platforms for stem cells: Current development and applications in wound healing	15
Exosomal miR-137-3p targets UBE3C to activate STAT3, promoting migration and differentiation into endometrial epithelial cell of human umbilical cord mesenchymal stem cells under hypoxia	15
Tumor necrosis factor-α inhibition restores matrix formation by human adipose-derived stem cells in the late stage of chondrogenic differentiation	15
Advancing mechanistic insights and clinical translation of exosomal miR-137-3p in endometrial regeneration	14
Extracellular vesicles: Emerged as a promising strategy for regenerative medicine	14
Current status and prospects of basic research and clinical application of mesenchymal stem cells in acute respiratory distress syndrome	14
Patient-derived induced pluripotent stem cells with a MERTK mutation exhibit cell junction abnormalities and aberrant cellular differentiation potential	14
Understanding and controlling the variables for advanced cell therapy	14
Treatment of syringomyelia using uncultured umbilical cord mesenchymal stem cells: A case report and review of literature	14
Banking of perinatal mesenchymal stem/stromal cells for stem cell-based personalized medicine over lifetime: Matters arising	13
Therapeutic potential of mesenchymal stem cells in neurodegenerative diseases	13
Mesenchymal stem/stromal cells as adjuvant therapy in COVID-19-associated acute lung injury and cytokine storm: Importance of cell identification	13
Repetitive administration of cultured human CD34+ cells improve adenine-induced kidney injury in mice	13
Mesenchymal stem cell exosomes enhance the development of hair follicle to ameliorate androgenetic alopecia	13
O-linked β-N-acetylglucosaminylation may be a key regulatory factor in promoting osteogenic differentiation of bone marrow mesenchymal stromal cells	12
Potential of ginsenoside Rg1 to treat aplastic anemia via mitogen activated protein kinase pathway in cyclophosphamide-induced myelosuppression mouse model	12
Innovative hydrogel delivery of bone marrow stromal cell-derived exosomes for enhanced bone healing	12
Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications	12
Recent progress in hair follicle stem cell markers and their regulatory roles	12
Cell-free extracts from human fat tissue attenuate ischemic injury in cardiomyocytes in a murine model	11
Refining adipose-derived stem cell isolation for optimal regenerative therapy	11
Effects of different concentrations of nicotinamide on hematopoietic stem cells cultured in vitro	11
Delineating the glioblastoma stemness by genes involved in cytoskeletal rearrangements and metabolic alterations	11
Inhibition of glutathione metabolism can limit the development of pancreatic cancer	11
Therapeutic effects of menstrual blood-derived endometrial stem cells on mouse models of streptozotocin-induced type 1 diabetes	11
Barriers to mesenchymal stromal cells for low back pain	11
Induced pluripotent stem cell-derived mesenchymal stem cells for modeling and treating metabolic associated fatty liver disease and metabolic associated steatohepatitis: Challenges and opportunities	10
Preliminary study on the preparation of lyophilized acellular nerve scaffold complexes from rabbit sciatic nerves with human umbilical cord mesenchymal stem cells	10
Crosstalk between Wnt and bone morphogenetic protein signaling during osteogenic differentiation	10
Applications of artificial intelligence in stem cell therapy	10
Molecular mechanism of therapeutic approaches for human gastric cancer stem cells	10
Adipokines regulate mesenchymal stem cell osteogenic differentiation	10
Living bio-drug therapies using mesenchymal stem cells and exosomes for mechanically ventilated patients with acute respiratory distress syndrome: A systematic review and meta-analysis	10
Quercetin ameliorates oxidative stress-induced senescence in rat nucleus pulposus-derived mesenchymal stem cells via the miR-34a-5p/SIRT1 axis	10
Immortalization of epidural fat-derived mesenchymal stem cells: In vitro characterization and adipocyte differentiation potential	10
Safety and efficiency of Wharton’s Jelly-derived mesenchymal stem cell administration in patients with traumatic brain injury: First results of a phase I study	10
Exploring the critical therapeutic window: Dose-frequency optimization of human umbilical cord mesenchymal stem cells for preclinical asthma treatment	10
Additional comments on extracellular vesicles derived from mesenchymal stem cells mediate extracellular matrix remodeling in osteoarthritis	10
Advances of nanotechnology applied to cancer stem cells	10
Expression of cancer stem cell markers and their prognostic significance in stage IIIA non-small cell lung cancer	10
Anti-fibrotic effect of adipose-derived stem cells on fibrotic scars	10
Bone marrow mesenchymal stem cell treatment improves post-stroke cerebral function recovery by regulating gut microbiota in rats	10
Combined mesenchymal and neural stem cell therapy enhances neurological recovery in cerebral infarction	10
Gossypol acetic acid regulates leukemia stem cells by degrading LRPPRC via inhibiting IL-6/JAK1/STAT3 signaling or resulting mitochondrial dysfunction	10
Synergism of calycosin and bone marrow-derived mesenchymal stem cells to combat podocyte apoptosis to alleviate adriamycin-induced focal segmental glomerulosclerosis	9

High glucose microenvironment and human mesenchymal stem cell behavior	9
Downregulation of miRNA-21 and cancer stem cells after chemotherapy results in better outcome in breast cancer patients	9
Stimulating factors for regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells	9
Overexpression of GATA binding protein 4 and myocyte enhancer factor 2C induces differentiation of mesenchymal stem cells into cardiac-like cells	9
Correction to “ADSC-Exos outperform BMSC-Exos in alleviating hydrostatic pressure-induced injury to retinal ganglion cells by upregulating nerve growth factors”	9
Stem cell transplantation in cerebrovascular accidents: A global bibliometric analysis (2000-2023)	9
Therapeutic applications of adipose-derived stromal vascular fractions in osteoarthritis	9
Circular RNAs inducing the osteogenic differentiation of dental mesenchymal stem cells via microRNA sponging	9
Strategies to improve the effect of mesenchymal stem cell therapy on inflammatory bowel disease	9
Innovative mesenchymal stem cell treatments for fatty liver disease	9
MiR-126 regulates the effect of mesenchymal stem cell vascular repair on carotid atherosclerosis through MAPK/ERK signaling pathway	9
Stem cell therapy: A promising therapeutic approach for skeletal muscle atrophy	9
Human umbilical cord mesenchymal stromal cell-derived extracellular vesicles alleviate radiation induced pulmonary fibrosis	8
Melanoma cell adhesion molecule-positive mesenchymal stromal cells alleviate acute respiratory distress syndrome via nuclear factor kappa-B-mediated para	8
Skinny people serum factors promote the differentiation of multipotent stem cells into brown adipose tissue	8
Engineering ligament tissues: Synergistic power of aligned nanofibers and cyclic stretch	8
Self-assembly of differentiated dental pulp stem cells facilitates spheroid human dental organoid formation and prevascularization	8
Strategies to improve regenerative potential of mesenchymal stem cells	8
How to enhance the ability of mesenchymal stem cells to alleviate intervertebral disc degeneration	8
Potential plausible role of Wharton’s jelly mesenchymal stem cells for diabetic bone regeneration	8
Preliminary evidence of renal function improvement in chronic progressive kidney disease using autologous CD34+ cell therapy: A clinical trial	8
Human dental pulp stem/stromal cells in clinical practice	8
WDR36 inhibits the osteogenic differentiation and migration of periodontal ligament stem cells	7
Silent saboteurs: How microplastics disrupt stem cells and tissue regeneration	7
Role of brahma-related gene 1/brahma-associated factor subunits in neural stem/progenitor cells and related neural developmental disorders	7
Mesenchymal stem cell-derived exosomes and the Wnt/β-catenin pathway: Unifying mechanisms of multi-organ regeneration and the path to precision clinical translation	7
Mesenchymal stem-derived exosomes enhance therapeutic benefits of exercise in isoproterenol-induced myocardial ischemia: Targeting ERK and Akt/mTOR signaling	7
Advances in human umbilical cord mesenchymal stem cells-derived extracellular vesicles and biomaterial assemblies for endometrial injury treatment	7
Umbilical cord mesenchymal stem cell exosomes alleviate necrotizing enterocolitis in neonatal mice by regulating intestinal epithelial cells autophagy	7
Efficacy and safety of umbilical cord-derived mesenchymal stem cell-conditioned media for preventing and treating skin aging	7
Therapeutic potential of urine-derived stem cells in renal regeneration following acute kidney injury: A comparative analysis with mesenchymal stem cells	7
Transcription regulators differentiate mesenchymal stem cells into chondroprogenitors, and their in vivo implantation regenerated the intervertebral disc degeneration	7
Stromal vascular fraction: Mechanisms and application in reproductive disorders	7
Application of mesenchymal stem cell therapy for premature ovarian insufficiency: Recent advances from mechanisms to therapeutics	7
Effects of macrophages on the osteogenic differentiation of adipose tissue-derived stem cells in two-dimensional and three-dimensional cocultures	7
Constitutive aryl hydrocarbon receptor facilitates the regenerative potential of mouse bone marrow mesenchymal stromal cells	7
Dissecting molecular mechanisms underlying ferroptosis in human umbilical cord mesenchymal stem cells: Role of cystathionine γ-lyase/hydrogen sulfide pathway	7
Molecular signaling in cancer stem cells of tongue squamous cell carcinoma: Therapeutic implications and challenges	7
Stem cell therapy for intervertebral disc degeneration: Clinical progress with exosomes and gene vectors	7
Bibliometrics of trends in global research on the roles of stem cells in myocardial fibrosis therapy	7
Emergence of the stromal vascular fraction and secretome in regenerative medicine	6
Mechanism of adipose-derived mesenchymal stem cell exosomes in the treatment of heart failure	6
Cyclodextrin host-guest complex to facilitate sinomenine-based osteoporosis therapy	6
Application of extracellular vesicles from mesenchymal stem cells promotes hair growth by regulating human dermal cells and follicles	6
Generation of a human haploid neural stem cell line for genome-wide genetic screening	6
Long non-coding RNA SNHG16 promotes human placenta-derived mesenchymal stem cell proliferation capacity through the PI3K/AKT pathway under hypoxia	6
Exosomes from circ-Astn1-modified adipose-derived mesenchymal stem cells enhance wound healing through miR-138-5p/SIRT1/FOXO1 axis regulation	6
Long noncoding ribonucleic acid ENST00000517482 enhances mesenchymal stem cell therapy against acute lung injury	6
Optimization of adipose tissue-derived mesenchymal stromal cells transplantation for bone marrow repopulation following irradiation	6
Reveal more mechanisms of precondition mesenchymal stem cells inhibiting inflammation	6
Human amniotic fluid stem cell therapy can help regain bladder function in type 2 diabetic rats	6
Childhood insulin resistance and neural stem cell dysfunction in psychiatric disorders: Role of de novo lipogenesis and treatment perspectives	6
Long noncoding RNAs in mesenchymal stromal/stem cells osteogenic differentiation: Implications in osteoarthritis pathogenesis	6
First-ever stem cell therapy restores insulin independence in type 1 diabetes: A medical milestone	6
HIF-1α modulates β-catenin pathway to enhance the survival and angiogenesis of PBMSCs under hypoxia environment	6
Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells alleviates myocardial injury by targeting thioredoxin-interacting protein-mediated hypoxia-inducible factor-1α pathway	5
Human umbilical cord mesenchymal stem cells ameliorate liver metabolism in diabetic rats with metabolic-associated fatty liver disease	5
Transplantation of human induced pluripotent stem cell derived keratinocytes accelerates deep second-degree burn wound healing	5
Application of stem cell-derived exosomes in bone and joint diseases: Recent advances enabled by diverse carrier technologies	5
Exosomes derived from microRNA-540-3p overexpressing mesenchymal stem cells promote immune tolerance via the CD74/nuclear factor-kappaB pathway in cardiac allograft	5
Mesenchymal stem cells-extracellular vesicles alleviate pulmonary fibrosis by regulating immunomodulators	5
VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling	5
Unravelling the reversion mechanisms of activated hepatic stellate cell properties by extracellular vesicles from mesenchymal stem cells	5
Hypoxia and inflammatory factor preconditioning enhances the immunosuppressive properties of human umbilical cord mesenchymal stem cells	5
Clinical application prospects and transformation value of dental follicle stem cells in oral and neurological diseases	5
Stem cell therapy applied for digestive anastomosis: Current state and future perspectives	5
X inactive-specific transcript regulates mitochondrial function and neuronal differentiation of stem cells via IGF2BP2/CPT1A axis in models of spinal cord injury	4
Obesity and cancer stem cells: Roles in cancer initiation, progression and therapy resistance	4
L-arginine from elder human mesenchymal stem cells induces angiogenesis and enhances therapeutic effects on ischemic heart diseases	4
Pretreatment can alleviate programmed cell death in mesenchymal stem cells	4
Sinomenine increases osteogenesis in mice with ovariectomy-induced bone loss by modulating autophagy	4
Human umbilical cord mesenchymal stem cells reduce platelet α-granule release in rats via the AKT/MEK/ERK pathway during acute exposure to high-altitude hypoxia	4
Multiple roles of mothers against decapentaplegic homolog 4 in tumorigenesis, stem cells, drug resistance, and cancer therapy	4
Optimal good manufacturing practice-compliant production of dental follicle stem cell sheet and its application in Sprague-Dawley rat periodontitis	4
L-arginine: A promising metabolite in enhancing the protective effects of adipose-derived stem cells against ischemic pathologies	4
When hematology meets ophthalmology: Cytomegalovirus retinitis in pediatric stem cell recipients	4
Culture and identification of neonatal rat brain-derived neural stem cells	4
Integrin beta 3-overexpressing mesenchymal stromal cells display enhanced homing and can reduce atherosclerotic plaque	4
Mesenchymal stem cells-derived exosomes alleviate radiation induced pulmonary fibrosis by inhibiting the protein kinase B/nuclear factor kappa B pathway	4
Dual role of extracellular vesicles in neurodegenerative diseases	3

Unveiling the role of hypoxia-inducible factor 2alpha in osteoporosis: Implications for bone health	3
Use of priming strategies to advance the clinical application of mesenchymal stromal/stem cell-based therapy	3
Immunomodulation: The next target of mesenchymal stem cell-derived exosomes in the context of ischemic stroke	3
Injectable hydrogel made from antler mesenchyme matrix for regenerative wound healing via creating a fetal-like niche	3
Quercetin pretreated umbilical cord mesenchymal stem cells alleviate inflammatory bowel disease via IL-10 /Janus kinase 2/STAT3 signaling	3
Non-coding RNAs in adipose-derived stem cell exosomes: Mechanisms, therapeutic potential, and challenges in wound healing	3
Immunomodulatory effects and clinical application of exosomes derived from mesenchymal stem cells	3
Resilience and challenges: Evaluating the impact of stress conditions on mesenchymal stem cells across different passages	3
Efficacy of serum-free cultured human umbilical cord mesenchymal stem cells in the treatment of knee osteoarthritis in mice	3
Extracellular vesicles from adipose-derived stem cells in bone regeneration: Mechanisms and therapeutic advances	3
Molecular and therapeutic effects of mesenchymal stem cell-derived exosomes on autoimmune diseases	3
Human pluripotent stem cell-derived kidney organoids: Current progress and challenges	3
Stem cell-derived biofactors fight against coronavirus infection	3
Human umbilical cord mesenchymal stem cell-derived exosomal miR-199a-3p inhibits the MAPK4/NF-κB signaling pathway to relieve osteoarthritis	3
Stem cell therapy for insulin-dependent diabetes: Are we still on the road?	3
Research progress and challenges in stem cell therapy for diabetic foot: Bibliometric analysis and perspectives	3
Mid-term outcomes of microfragmented adipose tissue plus arthroscopic surgery for knee osteoarthritis: A randomized, active-control, multicenter clinical trial	3
Interferon-gamma and tumor necrosis factor-alpha synergistically enhance the immunosuppressive capacity of human umbilical-cord-derived mesenchymal stem cells by increasing PD-L1 expression	3
Interplay between mesenchymal stem cells and macrophages: Promoting bone tissue repair	3
Challenges in the clinical translation of stromal vascular fraction therapy in regenerative medicine	2
Melatonin-based priming of stem cells to alleviate oxidative stress	2
Engineering the future of nanomedicine: Strategic approaches to extracellular vesicle-based drug administration regimens	2
Unlocking the versatile potential: Adipose-derived mesenchymal stem cells in ocular surface reconstruction and oculoplastics	2
Entering the era of living biopharmaceuticals for treating knee osteoarthritis: A systematic review and network meta-analysis	2
Potential regulatory effects of stem cell exosomes on inflammatory response in ischemic stroke treatment	2
Dual role and clinical application of extracellular vesicles in acute respiratory distress syndrome: Mechanism analysis and translational challenges	2
Soluble factors secreted by human Wharton’s jelly mesenchymal stromal/stem cells exhibit therapeutic radioprotection: A mechanistic study with integrating network biology	2
Effects of high glucose and severe hypoxia on the biological behavior of mesenchymal stem cells at various passages	2
Role of stem cells-based in facial nerve reanimation: A meta-analysis of histological and neurophysiological outcomes	2
Therapeutic strategies for intervertebral disc degeneration: Extracellular vesicles and microRNAs derived from mesenchymal stem cells	2
Perspectives on Schwann-like cells derived from bone marrow-mesenchymal stem cells: Advancing peripheral nerve injury therapies	2
Adult neural stem cells and schizophrenia	2
Zinc enhances the cell adhesion, migration, and self-renewal potential of human umbilical cord derived mesenchymal stem cells	2
Melatonin regulation and the function of the periodontal ligament: Future perspective and challenges	2
Asthma and stem cell therapy	2
Therapeutic potential of stem cell-derived exosomes in hair regeneration: A systematic review	2
Wumei Pills enhance intestinal stem cell - mediated repair in chemotherapy-induced mucositis via Lactobacillus reuteri - dependent modulation of the gut microbiota	2
Human mesenchymal stem cells exhibit altered mitochondrial dynamics and poor survival in high glucose microenvironment	2
Exosomal miR-203 from bone marrow stem cells targets the SOCS3/NF-κB pathway to regulate neuroinflammation in temporal lobe epilepsy	2
Effect of tandem autologous stem cell transplantation on survival in pediatric patients with high-risk solid tumors in South China	2
Adipose-derived regenerative therapies for the treatment of knee osteoarthritis	2
Effects of interleukin-10 treated macrophages on bone marrow mesenchymal stem cells via signal transducer and activator of transcription 3 pathway	2
Disagreements in the therapeutic use of mesenchymal stem cell-derived secretome	2
Abnormal lipid synthesis as a therapeutic target for cancer stem cells	2
Cardiac stem cells: Current knowledge and future prospects	2
GATA binding protein 2 mediated ankyrin repeat domain containing 26 high expression in myeloid-derived cell lines	2
Neural stem cells for Parkinson’s disease management: Challenges, nanobased support, and prospects	2
Outcomes of combined mitochondria and mesenchymal stem cells-derived exosome therapy in rat acute respiratory distress syndrome and sepsis	2
Thymoquinone inhibited the chondrogenic differentiation of tendon-derived stem cells caused by tendon injury	2
Microvesicles derived from mesenchymal stem cells inhibit acute respiratory distress syndrome-related pulmonary fibrosis in mouse partly through hepatocyte growth factor	2
Advances in mesenchymal stem cell therapy for lupus nephritis	2