World Journal of Stem Cells

Article	Citations
Mesenchymal stem cells secretome: The cornerstone of cell-free regenerative medicine	83
Glutathione metabolism is essential for self-renewal and chemoresistance of pancreatic cancer stem cells	48
Role of hypoxia preconditioning in therapeutic potential of mesenchymal stem-cell-derived extracellular vesicles	39
Therapeutic potential of periodontal ligament stem cells	39
Mesenchymal stem cell-derived small extracellular vesicles in the treatment of human diseases: Progress and prospect	38
Effect of metformin on stem cells: Molecular mechanism and clinical prospect	35
Multifunctional role of microRNAs in mesenchymal stem cell-derived exosomes in treatment of diseases	34
Potential therapeutic applications of mesenchymal stem cells for the treatment of eye diseases	31
Nanofat: A therapeutic paradigm in regenerative medicine	30
Neural stem cell therapy for brain disease	29
Mesenchymal stem cell-derived exosomes: A novel and potential remedy for cutaneous wound healing and regeneration	28
Exosomal microRNAs from mesenchymal stem/stromal cells: Biology and applications in neuroprotection	27
Biological, chemical and mechanical factors regulating migration and homing of mesenchymal stem cells	27
Stem cell quiescence and its clinical relevance	27
Stem cell therapies in tendon-bone healing	27
SOX transcription factors and glioma stem cells: Choosing between stemness and differentiation	26
Urolithin a alleviates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells through SIRT1/PGC-1α pathway	26
Adipose-derived stem cells: Pathophysiologic implications vs therapeutic potential in systemic sclerosis	25
Programmed cell death in stem cell-based therapy: Mechanisms and clinical applications	25
Translational products of adipose tissue-derived mesenchymal stem cells: Bench to bedside applications	25
Role and mechanism of neural stem cells of the subventricular zone in glioblastoma	25
Methods to produce induced pluripotent stem cell-derived mesenchymal stem cells: Mesenchymal stem cells from induced pluripotent stem cells	25
Effects of immune cells on mesenchymal stem cells during fracture healing	24
Prospects for the therapeutic development of umbilical cord blood-derived mesenchymal stem cells	24
Epigenetic regulation of dental pulp stem cells and its potential in regenerative endodontics	24

Umbilical cord-derived mesenchymal stem cells preconditioned with isorhamnetin: potential therapy for burn wounds	24
Current advances of stem cell-based therapy for kidney diseases	22
Mesenchymal stem cells as a potential therapeutic tool to cure cognitive impairment caused by neuroinflammation	21
Strategies to improve regenerative potential of mesenchymal stem cells	21
Modified mesenchymal stem cells in cancer therapy: A smart weapon requiring upgrades for wider clinical applications	21
Effects of shear stress on differentiation of stem cells into endothelial cells	21
Functional maturation of immature β cells: A roadblock for stem cell therapy for type 1 diabetes	21
Effects of storage media, supplements and cryopreservation methods on quality of stem cells	21
Stem cell therapy for heart failure: Medical breakthrough, or dead end?	20
Application of mesenchymal stem cells derived from human pluripotent stem cells in regenerative medicine	20
Role of platelets and breast cancer stem cells in metastasis	20
Recent trends in stem cell-based therapies and applications of artificial intelligence in regenerative medicine	19
Bone marrow mesenchymal stem cell therapy regulates gut microbiota to improve post-stroke neurological function recovery in rats	19
Differences and similarities between mesenchymal stem cell and endothelial progenitor cell immunoregulatory properties against T cells	19
Therapeutic prospects of mesenchymal stem/stromal cells in COVID-19 associated pulmonary diseases: From bench to bedside	19
Lipid droplets as metabolic determinants for stemness and chemoresistance in cancer	18
Perspectives of pluripotent stem cells in livestock	17
Platelet-rich plasma vs bone marrow aspirate concentrate: An overview of mechanisms of action and orthobiologic synergistic effects	17
Current evidence on potential of adipose derived stem cells to enhance bone regeneration and future projection	16
Review of the potential of mesenchymal stem cells for the treatment of infectious diseases	16
Calcium channels and their role in regenerative medicine	16
Cardiac stem cells: Current knowledge and future prospects	16
Modulating poststroke inflammatory mechanisms: Novel aspects of mesenchymal stem cells, extracellular vesicles and microglia	16
Influence of donor age on the differentiation and division capacity of human adipose-derived stem cells	15
Stem cell therapy and diabetic erectile dysfunction: A critical review	15
Stem cell therapy in ocular pathologies in the past 20 years	15
Exosomes derived from inflammatory myoblasts promote M1 polarization and break the balance of myoblast proliferation/differentiation	15
Transcription regulators differentiate mesenchymal stem cells into chondroprogenitors, and their in vivo implantation regenerated the intervertebral disc degeneration	14
Acupuncture accelerates neural regeneration and synaptophysin production after neural stem cells transplantation in mice	14
Epigenetic regulation of autophagy: A key modification in cancer cells and cancer stem cells	14
Multidifferentiation potential of dental-derived stem cells	14
Pancreatic β cell regeneration induced by clinical and preclinical agents	14
Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells alleviates myocardial injury by targeting thioredoxin-interacting protein-mediated hypoxia-inducible factor-1α pathway	14
Current understanding of mesenchymal stem cells in liver diseases	14
ARPE-19 conditioned medium promotes neural differentiation of adipose-derived mesenchymal stem cells	14
6-gingerol protects nucleus pulposus-derived mesenchymal stem cells from oxidative injury by activating autophagy	14
Antler stem cells and their potential in wound healing and bone regeneration	13
Different priming strategies improve distinct therapeutic capabilities of mesenchymal stromal/stem cells: Potential implications for their clinical use	13
First immunohistochemical evidence of human tendon repair following stem cell injection: A case report and review of literature	13
Novel insights for improving the therapeutic safety and efficiency of mesenchymal stromal cells	13
Advance in metabolism and target therapy in breast cancer stem cells	13
Dental stem cell-conditioned medium for tissue regeneration: Optimization of production and storage	12
Empty nose syndrome pathogenesis and cell-based biotechnology products as a new option for treatment	12
Understanding cellular and molecular mechanisms of pathogenesis of diabetic tendinopathy	12
Intratracheal administration of umbilical cord-derived mesenchymal stem cells attenuates hyperoxia-induced multi-organ injury via heme oxygenase-1 and JAK/STAT pathways	12
Stem cell therapies in cardiac diseases: Current status and future possibilities	12
Communication between bone marrow mesenchymal stem cells and multiple myeloma cells: Impact on disease progression	11
Age and genotype dependent erythropoietin protection in COVID-19	11
Factors affecting osteogenesis and chondrogenic differentiation of mesenchymal stem cells in osteoarthritis	11
Effects of normobaric cyclic hypoxia exposure on mesenchymal stem-cell differentiation–pilot study on bone parameters in elderly	11

Effect of glycyrrhizic acid and 18β-glycyrrhetinic acid on the differentiation of human umbilical cord-mesenchymal stem cells into hepatocytes	11
Why stem/progenitor cells lose their regenerative potential	11
Priming strategies for controlling stem cell fate: Applications and challenges in dental tissue regeneration	11
Alternative models of cancer stem cells: The stemness phenotype model, 10 years later	10
New insight into dental epithelial stem cells: Identification, regulation, and function in tooth homeostasis and repair	10
Molecular mechanism of therapeutic approaches for human gastric cancer stem cells	10
Advanced glycation end productions and tendon stem/progenitor cells in pathogenesis of diabetic tendinopathy	10
Exosomes from circ-Astn1-modified adipose-derived mesenchymal stem cells enhance wound healing through miR-138-5p/SIRT1/FOXO1 axis regulation	10
Anti-fibrotic effect of adipose-derived stem cells on fibrotic scars	10
Orthobiologics in the treatment of hip disorders	10
Patient-specific induced pluripotent stem cells as “disease-in-a-dish” models for inherited cardiomyopathies and channelopathies – 15 years of research	9
Hypoxia-inducible factor-1α–mediated upregulation of CD99 promotes the proliferation of placental mesenchymal stem cells by regulating ERK1/2	9
Clinical trials using dental stem cells: 2022 update	9
Epigenetic regulation by long noncoding RNAs in osteo-/adipogenic differentiation of mesenchymal stromal cells and degenerative bone diseases	9
Minibrain-related kinase/dual-specificity tyrosine-regulated kinase 1B implication in stem/cancer stem cells biology	9
Interferon-gamma and tumor necrosis factor-alpha synergistically enhance the immunosuppressive capacity of human umbilical-cord-derived mesenchymal stem cells by increasing PD-L1 expression	9
Clinical relevance of stem cells in lung cancer	9
Noninvasive in vivo cell tracking using molecular imaging: A useful tool for developing mesenchymal stem cell-based cancer treatment	9
Stem cell therapy: A paradigm shift in breast cancer treatment	9
Immunotherapy against programmed death-1/programmed death ligand 1 in hepatocellular carcinoma: Importance of molecular variations, cellular heterogeneity, and cancer stem cells	8
Insulin resistance in diabetes: The promise of using induced pluripotent stem cell technology	8
Heat shock protein 20 promotes sirtuin 1-dependent cell proliferation in induced pluripotent stem cells	8
Regulating the fate of stem cells for regenerating the intervertebral disc degeneration	8
Cell transplantation therapies for spinal cord injury focusing on bone marrow mesenchymal stem cells: Advances and challenges	8
Application of extracellular vesicles from mesenchymal stem cells promotes hair growth by regulating human dermal cells and follicles	8
Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications	8
Extracellular vesicles: Emerged as a promising strategy for regenerative medicine	8
Feasibility of allogeneic mesenchymal stem cells in pediatric hypoxic-ischemic encephalopathy: Phase I study	8
Intercellular mitochondrial transfer as a means of revitalizing injured glomerular endothelial cells	8
Roles of mitochondrial unfolded protein response in mammalian stem cells	8
Retina stem cells, hopes and obstacles	8
Epigenetic modulators for brain cancer stem cells: Implications for anticancer treatment	8
Recent advances in stem cell therapy for neurodegenerative disease: Three dimensional tracing and its emerging use	8
miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma via a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc	8
Dental mesenchymal stromal/stem cells in different microenvironments— implications in regenerative therapy	7
Abnormal lipid synthesis as a therapeutic target for cancer stem cells	7
Application of cattle placental stem cells for treating ovarian follicular cyst	7
Immunomodulation: The next target of mesenchymal stem cell-derived exosomes in the context of ischemic stroke	7
Neural stem cells for Parkinson’s disease management: Challenges, nanobased support, and prospects	7
Stem cell therapy for insulin-dependent diabetes: Are we still on the road?	7
Advances of nanotechnology applied to cancer stem cells	6
Isolation and characterization of mesenchymal stem cells in orthopaedics and the emergence of compact bone mesenchymal stem cells as a promising surgical adjunct	6
Inter-regulatory role of microRNAs in interaction between viruses and stem cells	6
Vascularization and osteogenesis in ectopically implanted bone tissue-engineered constructs with endothelial and osteogenic differentiated adipose-derived stem cells	6
Application of adipose-derived stem cells in treating fibrosis	6
Zinc enhances the cell adhesion, migration, and self-renewal potential of human umbilical cord derived mesenchymal stem cells	6
Treatment of acute ischemic stroke by minimally manipulated umbilical cord-derived mesenchymal stem cells transplantation: A case report	6
Overexpression of GATA binding protein 4 and myocyte enhancer factor 2C induces differentiation of mesenchymal stem cells into cardiac-like cells	6
Growing and aging of hematopoietic stem cells	6
Potential regulatory effects of stem cell exosomes on inflammatory response in ischemic stroke treatment	6
Adipokines regulate mesenchymal stem cell osteogenic differentiation	6
Low complexity domains, condensates, and stem cell pluripotency	6
Therapeutic effects of menstrual blood-derived endometrial stem cells on mouse models of streptozotocin-induced type 1 diabetes	6
Overview of nutritional approach in hematopoietic stem cell transplantation: COVID-19 update	6
Proliferation and tenogenic differentiation of bone marrow mesenchymal stem cells in a porous collagen sponge scaffold	6
Immunophenotypic characteristics of multipotent mesenchymal stromal cells that affect the efficacy of their use in the prevention of acute graft vs host disease	6
Therapeutic applications of adipose-derived stromal vascular fractions in osteoarthritis	6
Mesenchymal stem cells and COVID-19: What they do and what they can do	6
Alternative RNA splicing in stem cells and cancer stem cells: Importance of transcript-based expression analysis	6
Strategies to improve the effect of mesenchymal stem cell therapy on inflammatory bowel disease	6
Mesenchymal stem cells in ischemic tissue regeneration	6
Bone marrow mesenchymal stem cell-derived exosomal microRNAs target PI3K/Akt signaling pathway to promote the activation of fibroblasts	6
Disease modifying treatment of spinal cord injury with directly reprogrammed neural precursor cells in non-human primates	6
Stem cell-derived biofactors fight against coronavirus infection	6
Multiple roles of mothers against decapentaplegic homolog 4 in tumorigenesis, stem cells, drug resistance, and cancer therapy	6
Reporter gene systems for the identification and characterization of cancer stem cells	6
Hypoxia and inflammatory factor preconditioning enhances the immunosuppressive properties of human umbilical cord mesenchymal stem cells	6
Clinical application prospects and transformation value of dental follicle stem cells in oral and neurological diseases	6
Adult neural stem cells and schizophrenia	6
Regulation of the mesenchymal stem cell fate by interleukin-17: Implications in osteogenic differentiation	6
Mesenchymal stem cells for enhancing biological healing after meniscal injuries	6
Crosstalk between Wnt and bone morphogenetic protein signaling during osteogenic differentiation	5
Effect of conditioned medium from neural stem cells on glioma progression and its protein expression profile analysis	5
Application of exosome-derived noncoding RNAs in bone regeneration: Opportunities and challenges	5
Optimal concentration of mesenchymal stem cells for fracture healing in a rat model with long bone fracture	5
Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targeting	5
Modulation of stem cell fate in intestinal homeostasis, injury and repair	5
Application of dental stem cells in three-dimensional tissue regeneration	5
Quercetin ameliorates oxidative stress-induced senescence in rat nucleus pulposus-derived mesenchymal stem cells via the miR-34a-5p/SIRT1 axis	5
Spinal cord injury regeneration using autologous bone marrow-derived neurocytes and rat embryonic stem cells: A comparative study in rats	5

Targeting mesenchymal stem cell therapy for severe pneumonia patients	5
Considerations for the clinical use of stem cells in genitourinary regenerative medicine	5
Treatment of syringomyelia using uncultured umbilical cord mesenchymal stem cells: A case report and review of literature	5
Stimulating factors for regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells	5
Central nervous system tumors and three-dimensional cell biology: Current and future perspectives in modeling	5
Changes of cell membrane fluidity for mesenchymal stem cell spheroids on biomaterial surfaces	5
Review of operative considerations in spinal cord stem cell therapy	5
Regulators of liver cancer stem cells	5
Correlation between amino acid metabolism and self-renewal of cancer stem cells: Perspectives in cancer therapy	5
SPOC domain-containing protein 1 regulates the proliferation and apoptosis of human spermatogonial stem cells through adenylate kinase 4	5
Advancements in adipose-derived stem cell therapy for skin fibrosis	5
Maternal inappropriate calcium intake aggravates dietary-induced obesity in male offspring by affecting the differentiation potential of mesenchymal stem cells	4
Mechanisms of analgesic effect of mesenchymal stem cells in osteoarthritis pain	4
Human retinal secretome: A cross-link between mesenchymal and retinal cells	4
Disagreements in the therapeutic use of mesenchymal stem cell-derived secretome	4
Cellular preconditioning and mesenchymal stem cell ferroptosis	4
Acquired aplastic anemia: Is bystander insult to autologous hematopoiesis driven by immune surveillance against malignant cells?	4
Downregulation of miRNA-21 and cancer stem cells after chemotherapy results in better outcome in breast cancer patients	4
Combination of mesenchymal stem cells and three-dimensional collagen scaffold preserves ventricular remodeling in rat myocardial infarction model	4
Human mesenchymal stem cells exhibit altered mitochondrial dynamics and poor survival in high glucose microenvironment	4
Banking of perinatal mesenchymal stem/stromal cells for stem cell-based personalized medicine over lifetime: Matters arising	4
Genome engineering and disease modeling via programmable nucleases for insulin gene therapy; promises of CRISPR/Cas9 technology	4
AlCl3 exposure regulates neuronal development by modulating DNA modification	4
Induced pluripotent stem cells as suitable sensors for fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome	4
Effects of exosomes from mesenchymal stem cells on functional recovery of a patient with total radial nerve injury: A pilot study	4
Immunotherapy in the treatment of lymphoma	4