Science Translational Medicine

Papers
(The TQCC of Science Translational Medicine is 38. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
IgA dominates the early neutralizing antibody response to SARS-CoV-2829
Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19496
Enhanced SARS-CoV-2 neutralization by dimeric IgA385
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates342
COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters338
Importance of the pig as a human biomedical model315
SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma262
A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus259
Lung transplantation for patients with severe COVID-19252
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis247
Advanced bandages for diabetic wound healing236
The past, present, and future of antibiotics224
Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors204
Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection204
Prospects for a safe COVID-19 vaccine198
Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2187
Sampling interstitial fluid from human skin using a microneedle patch182
Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces viral shedding after SARS-CoV-2 D614G challenge in preclinical models175
Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals174
A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma173
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia171
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19166
Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide165
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity164
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages164
Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection163
The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans161
Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome156
Acute inflammatory response via neutrophil activation protects against the development of chronic pain152
iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti–PD-1 therapy151
Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19150
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery149
Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in lungs of African green monkeys146
Reproducibility in machine learning for health research: Still a ways to go143
Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases141
Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy134
Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms134
T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals133
In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer’s disease pathology and cognitive decline132
Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease132
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection131
Antitumor activity without on-target off-tumor toxicity of GD2–chimeric antigen receptor T cells in patients with neuroblastoma131
Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines130
Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models129
Smartwatch inertial sensors continuously monitor real-world motor fluctuations in Parkinson’s disease129
SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor activity in mouse models128
The cortical origin and initial spread of medial temporal tauopathy in Alzheimer’s disease assessed with positron emission tomography126
Reprogramming lipid metabolism prevents effector T cell senescence and enhances tumor immunotherapy126
Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms126
Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils125
Exercise-induced piezoelectric stimulation for cartilage regeneration in rabbits125
SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19124
Nicotinamide for the treatment of heart failure with preserved ejection fraction123
Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses119
Toward robust mammography-based models for breast cancer risk119
DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia116
Chi3l1 /YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer’s disease pathogenesis114
Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade113
Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy113
Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment113
Predicting the mutational drivers of future SARS-CoV-2 variants of concern112
Intracavity generation of glioma stem cell–specific CAR macrophages primes locoregional immunity for postoperative glioblastoma therapy108
Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models107
MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates107
Combination of metabolic intervention and T cell therapy enhances solid tumor immunotherapy107
Granzyme K + CD8 T cells form a core population in inflamed human tissue106
mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions105
Undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the United States105
A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles104
MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases104
Wireless sensors for continuous, multimodal measurements at the skin interface with lower limb prostheses104
Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair103
Delivery mode and gut microbial changes correlate with an increased risk of childhood asthma102
Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates102
Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury99
Targeting cartilage EGFR pathway for osteoarthritis treatment99
Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease98
Brain circuits for pain and its treatment98
Omicron variant Spike-specific antibody binding and Fc activity are preserved in recipients of mRNA or inactivated COVID-19 vaccines97
Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses96
An off-the-shelf bioadhesive patch for sutureless repair of gastrointestinal defects95
Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses95
Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy95
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease94
Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor94
Using deep learning for dermatologist-level detection of suspicious pigmented skin lesions from wide-field images94
A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice94
Oncolytic virus–mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice92
In vivo prime editing of a metabolic liver disease in mice92
Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset91
Glutamine promotes antibiotic uptake to kill multidrug-resistant uropathogenic bacteria90
A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence89
MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation89
Trispecific CD19-CD20-CD22–targeting duoCAR-T cells eliminate antigen-heterogeneous B cell tumors in preclinical models88
A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates88
A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models88
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern87
A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes87
APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function86
A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma86
Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models86
Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans85
Lung cancer scRNA-seq and lipidomics reveal aberrant lipid metabolism for early-stage diagnosis84
An oral antisense oligonucleotide for PCSK9 inhibition83
SARS-CoV-2 3CL pro mutations selected in a VSV-based system confer resistance to nirmatrelvir, ensitrelvir, and GC37683
Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment83
Soft, skin-interfaced sweat stickers for cystic fibrosis diagnosis and management83
mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent82
Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade81
Extracellular vesicles deposit PCNA to rejuvenate aged bone marrow–derived mesenchymal stem cells and slow age-related degeneration81
Key epidemiological drivers and impact of interventions in the 2020 SARS-CoV-2 epidemic in England81
Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity80
AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein–specific T H 1 response with a diverse TCR repertoire80
Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity80
An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer’s disease80
COVID-19 mRNA vaccines drive differential antibody Fc-functional profiles in pregnant, lactating, and nonpregnant women79
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due toTTNmutations79
Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS79
Chimeric STAR receptors using TCR machinery mediate robust responses against solid tumors78
Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition78
Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort78
Persistent post–COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium77
Cardiac ryanodine receptor calcium release deficiency syndrome76
Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models75
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice75
Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers75
Stereotypic neutralizing V H antibodies against SARS-CoV-2 spike protein receptor binding domain in patients with COVID-19 and healthy individuals75
Gene therapy knockdown of Hippo signaling induces cardiomyocyte renewal in pigs after myocardial infarction75
Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum74
SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies74
TRIB3 reduces CD8 + T cell infiltration and induces immune evasion by repressing the STAT1-CXCL10 axis in colorectal cancer74
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis74
Long-lasting analgesia via targeted in situ repression of Na V 1.7 in mice74
Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia73
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia73
A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia73
Academic careers and the COVID-19 pandemic: Reversing the tide72
Platelets release mitochondrial antigens in systemic lupus erythematosus72
Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies72
Blockade of the CD93 pathway normalizes tumor vasculature to facilitate drug delivery and immunotherapy72
Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model72
SARS-CoV-2 BA.1 variant is neutralized by vaccine booster–elicited serum but evades most convalescent serum and therapeutic antibodies71
A high-throughput cell- and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma70
Druggable cancer phosphatases69
Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation69
CECR2 drives breast cancer metastasis by promoting NF-κB signaling and macrophage-mediated immune suppression69
Mutant huntingtin and neurofilament light have distinct longitudinal dynamics in Huntington’s disease69
SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice69
Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host disease68
Citrullinated vimentin mediates development and progression of lung fibrosis68
Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro68
Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-1967
Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA67
AD-linked R47H-TREM2mutation induces disease-enhancing microglial states via AKT hyperactivation67
SARS-CoV-2 infection drives an inflammatory response in human adipose tissue through infection of adipocytes and macrophages67
Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin66
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis66
Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel65
Elastin-like recombinamers-based hydrogel modulates post-ischemic remodeling in a non-transmural myocardial infarction in sheep65
Attenuation of peripheral serotonin inhibits tumor growth and enhances immune checkpoint blockade therapy in murine tumor models64
Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy64
A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults64
A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression63
Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice63
An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice63
A microRNA-21–mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis63
Development and deployment of COVID-19 vaccines for those most vulnerable63
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia63
Human brain mapping with multithousand-channel PtNRGrids resolves spatiotemporal dynamics62
Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair62
scRNA-seq of human vitiligo reveals complex networks of subclinical immune activation and a role for CCR5 in T reg function62
A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models62
LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade62
Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis62
Development of ICT01, a first-in-class, anti-BTN3A antibody for activating Vγ9Vδ2 T cell–mediated antitumor immune response62
Risk assessment with gut microbiome and metabolite markers in NAFLD development61
Cardiosphere-derived exosomal microRNAs for myocardial repair in pediatric dilated cardiomyopathy61
Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests61
Overcoming microenvironmental resistance to PD-1 blockade in genetically engineered lung cancer models61
Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype60
Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses60
A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters60
Reactive oxygen species–degradable polythioketal urethane foam dressings to promote porcine skin wound repair59
Depleting plasmacytoid dendritic cells reduces local type I interferon responses and disease activity in patients with cutaneous lupus59
Plasma neurofilament light predicts mortality in patients with stroke59
Oligodendrocyte-derived extracellular vesicles as antigen-specific therapy for autoimmune neuroinflammation in mice59
Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy59
Receptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different species59
Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption58
Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer’s disease57
Treatment of a genetic brain disease by CNS-wide microglia replacement57
Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis57
Combining a CAR and a chimeric costimulatory receptor enhances T cell sensitivity to low antigen density and promotes persistence57
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts57
Mechanism and reversal of drug-induced nephrotoxicity on a chip57
Mitochondrial metabolic reprogramming controls the induction of immunogenic cell death and efficacy of chemotherapy in bladder cancer57
A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer57
A chimeric antigen receptor with antigen-independent OX40 signaling mediates potent antitumor activity56
A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae56
Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates56
Infection or a third dose of mRNA vaccine elicits neutralizing antibody responses against SARS-CoV-2 in kidney transplant recipients55
Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy55
Static lung storage at 10°C maintains mitochondrial health and preserves donor organ function55
Mechanism of praziquantel action at a parasitic flatworm ion channel55
Necrotizing enterocolitis induces T lymphocyte–mediated injury in the developing mammalian brain54
Immunotherapy combinations overcome resistance to bispecific T cell engager treatment in T cell–cold solid tumors54
Association of a common genetic variant with Parkinson’s disease is mediated by microglia54
CD4 + T cells are essential for the development of destructive thyroiditis induced by anti–PD-1 antibody in thyroglobulin-immunized mice53
Imaging Enterobacterales infections in patients using pathogen-specific positron emission tomography53
Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers53
Characterization of immune responses in fully vaccinated individuals after breakthrough infection with the SARS-CoV-2 delta variant53
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice53
Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates53
Tissue-resident CD8 + T cells drive compartmentalized and chronic autoimmune damage against CNS neurons52
LINE-1 RNA causes heterochromatin erosion and is a target for amelioration of senescent phenotypes in progeroid syndromes52
Systemic cancer therapy with engineered adenovirus that evades innate immunity52
Gastric dysfunction in patients with chronic nausea and vomiting syndromes defined by a noninvasive gastric mapping device52
Genetic analysis of praziquantel response in schistosome parasites implicates a transient receptor potential channel52
Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity51
NUAK1 promotes organ fibrosis via YAP and TGF-β/SMAD signaling51
The microbiota in pneumonia: From protection to predisposition51
Albumin nanoparticle containing a PI3Kγ inhibitor and paclitaxel in combination with α-PD1 induces tumor remission of breast cancer in mice51
Fusobacterium infection facilitates the development of endometriosis through the phenotypic transition of endometrial fibroblasts51
Viral genomes reveal patterns of the SARS-CoV-2 outbreak in Washington State51
S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters50
Bacteria-specific phototoxic reactions triggered by blue light and phytochemical carvacrol50
Prosaposin mediates inflammation in atherosclerosis50
Fetal lung underdevelopment is rescued by administration of amniotic fluid stem cell extracellular vesicles in rodents50
Synaptogenic effect of APP -Swedish mutation in familial Alzheimer’s disease50
Analysis of recurrently protected genomic regions in cell-free DNA found in urine50
A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer’s disease50
Targeting AKR1B1 inhibits glutathione de novo synthesis to overcome acquired resistance to EGFR-targeted therapy in lung cancer50
Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q50
Plasma exosomal miR-375-3p regulates mitochondria-dependent keratinocyte apoptosis by targeting XIAP in severe drug-induced skin reactions49
Transient receptor potential canonical 5 mediates inflammatory mechanical and spontaneous pain in mice49
NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models49
Proinflammatory CD20 + T cells contribute to CNS-directed autoimmunity49
MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration49
A decision algorithm to promote outpatient antimicrobial stewardship for uncomplicated urinary tract infection49
A shift in lung macrophage composition is associated with COVID-19 severity and recovery49
4-Aminopyridine is a promising treatment option for patients with gain-of-function KCNA2 -encephalopathy49
Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in mice49
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS48
A bivalent Epstein-Barr virus vaccine induces neutralizing antibodies that block infection and confer immunity in humanized mice48
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G 4 C 2 ) repeat expansion in vitro and in vivo ALS models48
APOE3 -Jacksonville (V236E) variant reduces self-aggregation and risk of dementia48
The rapid replacement of the SARS-CoV-2 Delta variant by Omicron (B.1.1.529) in England48
The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer’s disease48
The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration48
Skeletal muscle regeneration with robotic actuation–mediated clearance of neutrophils48
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