Science Translational Medicine

Article	Citations
Increased brain microvascular hemoglobin concentrations in children with cerebral malaria	559
SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8 + T cells	326
Transcriptome-based identification of tumor-reactive and bystander CD8 + T cell receptor clonotypes in human pancreatic cancer	311
In silico screening and preclinical validation identify bavisant as a therapeutic candidate for multiple sclerosis	269
Combination bezafibrate and nivolumab treatment of patients with advanced non–small cell lung cancer	255
Podocyte YAP and TAZ hyperactivation drives glomerular epithelial proliferative diseases in mice and humans	245
AGER-dependent macropinocytosis drives resistance to KRAS-G12D–targeted therapy in advanced pancreatic cancer	236
The rapid replacement of the SARS-CoV-2 Delta variant by Omicron (B.1.1.529) in England	225
Resilient nanostructured bioanalytic microneedle longitudinally monitors preclinical renal and hepatic drug clearance and dysfunction	223
Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting	220
Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment	206
Integrated analysis of blood DNA methylation, genetic variants, circulating proteins, microRNAs, and kidney failure in type 1 diabetes	205
Evolution of inflammation and immunity in a dengue virus 1 human infection model	190
A tale of two cells: Regulatory T cell–microglia cross-talk in the ischemic brain	177
Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms	171
Stronger regulation of AI in biomedicine	168
A first-in-human study of the fibroblast activation protein–targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors	167
Metabolic reprogramming of skeletal muscle by resident macrophages points to CSF1R inhibitors as muscular dystrophy therapeutics	156
A prefusion-stabilized RSV F subunit vaccine elicits B cell responses with greater breadth and potency than a postfusion F vaccine	154
TrkA-mediated sensory innervation of injured mouse tendon supports tendon sheath progenitor cell expansion and tendon repair	153
Engineering CAR-T therapies for autoimmune disease and beyond	149
In vivo gene immunotherapy for cancer	148
Advancing beyond the twists and turns of T cell exhaustion in cancer	146
Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment	141
Characterization of the SARS-CoV-2 B.1.621 (Mu) variant	135

Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation	135
A protein-free vaccine stimulates innate immunity and protects against nosocomial pathogens	134
Germline-encoded recognition of peanut underlies development of convergent antibodies in humans	133
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery	131
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome	131
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies	130
Antigenic distance between primary and secondary dengue infections correlates with disease risk	129
Genomic and epigenomic BRCA alterations predict adaptive resistance and response to platinum-based therapy in patients with triple-negative breast and ovarian carcinomas	128
Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging	128
Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis	121
Preclinical evaluation of antisense oligonucleotide therapy in a mouse model of HNRNPH2 -related neurodevelopmental disorder	121
PET imaging of antisense oligonucleotide distribution in rat and nonhuman primate brains using click chemistry	120
NAD + precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction	119
Repeated COVID-19 mRNA-based vaccination contributes to SARS-CoV-2 neutralizing antibody responses in the mucosa	117
MEK1/2 inhibitors suppress pathological α-synuclein and neurotoxicity in cell models and a humanized mouse model of Parkinson’s disease	116
Improved control of a prosthetic limb by surgically creating electro-neuromuscular constructs with implanted electrodes	115
Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation	112
Pseudomonas aeruginosa infection induces intragraft lymphocytotoxicity that triggers lung transplant antibody-mediated rejection	112
Molecular hallmarks of hydrocephalus	112
TREM1 activation of myeloid cells promotes antitumor immunity	111
Actin depolymerization promotes axon regeneration by restoring axonal mitochondrial transport in mouse models of optic neuropathy	111
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice	111
Integrating the gut microbiome and pharmacology	110
Rapid closure and hemostasis of ruptured soft tissues using a modified human tropoelastin-based sealant in preclinical models	110
The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipron	109
Generating functionally stable and antigen-specific T reg cells from effector T cells for cell therapy of inflammatory diseases	108
Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma	108
Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models	105
Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe	104
Next-generation CAR T cell therapies for glioblastoma	103
The oncomodulin receptor ArmC10 enables axon regeneration in mice after nerve injury and neurite outgrowth in human iPSC–derived sensory neurons	101
Systemic administration of an RNA binding and cell-penetrating antibody targets therapeutic RNA to multiple mouse models of cancer	100
A human histidyl-tRNA synthetase splice variant therapeutic targets NRP2 to resolve lung inflammation and fibrosis	100
Development and preclinical validation of 2-deoxy 2-[ 18 F]fluorocellobiose as an Aspergillus -specific PET tracer	100
Sexually dimorphic differences in angiogenesis markers are associated with brain aging trajectories in humans	99
The pancreatic clock is a key determinant of pancreatic fibrosis progression and exocrine dysfunction	97
FcγR-targeted tuftsin clusters rejuvenate macrophages in preclinical sepsis–associated secondary infection	97
Translating insights into therapies for Long Covid	97
Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy	95
BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease	94
Follistatin drives neuropathic pain in mice through IGF1R signaling in nociceptive neurons	94
Found in translation—Fibrosis in metabolic dysfunction–associated steatohepatitis (MASH)	94
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer’s disease	93
Chaperone-mediated autophagy supports organ regeneration and fibroblast quiescence in mouse models of fibrosis	93
Farnesoid X receptor antagonizes macrophage-dependent licensing of effector T lymphocytes and progression of sclerosing cholangitis	93
Assessment of cholesterol homeostasis in the living human brain	91
A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis	90
Postoperative adhesions are abrogated by a sustained-release anti-JUN therapeutic in preclinical models	90
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria	90
Diet shapes the metabolite profile in the intact human ileum, which affects PYY release	90

Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice	90
Extracellular BRICK1 drives heart repair after myocardial infarction in mice	89
Small-molecule inhibition of YTHDC1 as a strategy against acute myeloid leukemia in mouse models	89
BDNF Val 66 Met protects oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer	88
T cell receptor precision editing of regulatory T cells for celiac disease	88
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment	88
Adaptive cognitive control circuit changes associated with problem-solving ability and depression symptom outcomes over 24 months	87
Obesity and lifespan, a complex tango	87
Comparing antibody assays as correlates of protection against COVID-19 in the COVE mRNA-1273 vaccine efficacy trial	87
Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer	85
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria	85
Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders	84
Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for Mycobacterium tuberculosis	84
A nose for tau	84
Myeloid MAS–driven macrophage efferocytosis promotes resolution in ischemia-stressed mouse and human livers	84
Short-course combination treatment for experimental chronic Chagas disease	83
Serial multiomics uncovers anti-glioblastoma responses not evident by routine clinical analyses	83
Cationic nanogel–based nasal therapeutic HPV vaccine prevents the development of cervical cancer	82
Harnessing regulatory T cells to establish immune tolerance	82
Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration	81
Wastewater surveillance facilitates climate change–resilient pathogen monitoring	81
The adenosine analog prodrug ATV006 is orally bioavailable and has preclinical efficacy against parental SARS-CoV-2 and variants	80
Calprotectin is a contributor to and potential therapeutic target for vascular calcification in chronic kidney disease	80
Anakinra restores immunological misfiring that drives influenza-associated pulmonary aspergillosis	78
The m 6 A demethylase FTO links TLR7 to mitochondrial oxidation driving age-associated B cell formation in systemic lupus erythematosus	78
Mitochondrial augmentation of hematopoietic stem cells in children with single large-scale mitochondrial DNA deletion syndromes	77
Leucine-rich α-2-glycoprotein 1 initiates the onset of diabetic retinopathy in mice	77
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins	76
CD23 + IgG1 + memory B cells are poised to switch to pathogenic IgE production in food allergy	76
Historic 1994 influenza vaccine cohorts define breadth of antibody and B cell responses toward future influenza A and B viruses	76
Erratum for the Research Article “A functional identification platform reveals frequent, spontaneous neoantigen-specific T cell responses in patients with cancer” by A. M. Miller <	76
Antibody-mediated prevention of vaginal HIV transmission is dictated by IgG subclass in humanized mice	76
Inhibiting SLC38A2 lowers blood pressure in rodent models of hypertension	76
A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis	75
Targeting ryanodine receptor type 2 to mitigate chemotherapy-induced neurocognitive impairments in mice	74
Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever virus infection	74
Collagen V regulates renal function after kidney injury and can be pharmacologically targeted to enhance kidney repair in mice	74
Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice	74
Clonal hematopoiesis detection in patients with cancer using cell-free DNA sequencing	72
A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria	72
Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases	71
Targeting cytokines in inflammatory bowel disease	70
IgE in allergy: It takes two	70
Lymphatic disruption drives lung transplant fibrosis through interleukin-1–mediated hyaluronan accumulation	70
Green light analgesia in mice is mediated by visual activation of enkephalinergic neurons in the ventrolateral geniculate nucleus	69
Simultaneous analysis of mutations and methylations in circulating cell-free DNA for hepatocellular carcinoma detection	68
NFIA regulates articular chondrocyte fatty acid metabolism and joint homeostasis	68
An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans	68
T STEM -like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models	68
SV2A-PET imaging uncovers cortical synapse loss in multiple sclerosis	67
Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice	66
Antibody Fc characteristics and effector functions correlate with protection from symptomatic dengue virus type 3 infection	66
SARS-CoV-2 induces neutrophil degranulation and differentiation into myeloid-derived suppressor cells associated with severe COVID-19	66
Sex, lean body mass, and cardiac performance	66
A cross-talk established by tumor-targeted cytokines rescues CAR T cell activity and engages host T cells against glioblastoma in mice	66
Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia	65
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis	65
Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis	64
Immune responses to gut bacteria associated with time to diagnosis and clinical response to T cell–directed therapy for type 1 diabetes prevention	64
An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor	63
Multiomic analyses of longitudinal plasma samples identify thromboinflammation endotypes and trajectories in patients with trauma	63
Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation	63
MicroRNA-142-3p shuttling in extracellular vesicles marks regulatory T cell dysfunction in multiple sclerosis	62
Translating the evolving molecular landscape of tumors to biomarkers of response for cancer immunotherapy	62
Synthetic biology–driven induction of mature TLS formation enhances antitumor immunity in colorectal cancer	62
Erratum for the Research Article “Platelet-derived growth factor C signaling is a potential therapeutic target for radiation proctopathy” by W. Lu et al	61
Metabolic surgery reduces CRC disease progression through circulating bile acid diversion	61
Erratum for the Research Article “Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4” by Y. Ren et al .	61
Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non–small cell lung cancer	61
Genetic and structural aspects of amyloid diseases	60
Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers	59
Expression of the excitatory opsin ChRERα can be traced longitudinally in rat and nonhuman primate brains with PET imaging	59
Comment on “A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk”	59
Resident microbes shape the vaginal epithelial glycan landscape	59
Spatial genomics: Mapping the landscape of fibrosis	59
A peptide immunomodulator activates MST1 to expand and stabilize murine and human regulatory T cells for immune tolerance	58
Prostate tissue ablation and drug delivery by an image-guided injectable ionic liquid in ex vivo and in vivo models	58
Gastric dysfunction in patients with chronic nausea and vomiting syndromes defined by a noninvasive gastric mapping device	58
In vivo Bruton’s tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis	58
A germline SNP in BRMS1 predisposes patients with lung adenocarcinoma to metastasis and can be ameliorated by targeting c-fos	58

Design of a neutralizing and protective pan–encephalitic alphavirus receptor decoy protein	58
Repeated Omicron exposures redirect SARS-CoV-2–specific memory B cell evolution toward the latest variants	58
Flortaucipir PET uncovers relationships between tau and amyloid-β in primary age–related tauopathy and Alzheimer’s disease	57
Single-cell atlas of human infrapatellar fat pad and synovium implicates APOE signaling in osteoarthritis pathology	57
Adeno-associated virus gene therapy–mediated CCR5 blockade suppresses virus replication long term in SHIV-infected macaques	57
Inhibition of MERTK reduces organ fibrosis in mouse models of fibrotic disease	57
New government drug repurposing programs: Opportunities and uncertainties	57
A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma	57
Genipin rescues developmental and degenerative defects in familial dysautonomia models and accelerates axon regeneration	56
Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice	56
Blocking common γ chain cytokine signaling ameliorates T cell–mediated pathogenesis in disease models	56
Human OX40L–CAR-T regs target activated antigen-presenting cells and control T cell alloreactivity	56
Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheimer’s disease	56
A replicating RNA vaccine protects cynomolgus macaques against lethal clade 2.3.4.4b influenza A H5N1 virus challenge	55
Delivery of therapeutic carbon monoxide by gas-entrapping materials	55
Seeking satiety: From signals to solutions	55
Interleukin-2–based therapies in cancer	54
Targeting Src reactivates pyroptosis to reverse chemoresistance in lung and pancreatic cancer models	54
Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer	54
Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β–mediated inflammation in mice and humans	54
Allergy: Mechanistic insights into new methods of prevention and therapy	53
Gut pathogen colonization precedes bloodstream infection in the neonatal intensive care unit	53
Beta-blockade enhances anthracycline control of metastasis in triple-negative breast cancer	53
Lowering the HTT1a transcript as an effective therapy for Huntington’s disease in a knockin mouse model	53
Neuroinflammation: An astrocyte perspective	53
An inactivated trivalent virion-based vaccine protects against aerosol challenge with encephalitic alphaviruses in mice and macaques	52
Preclinical efficacy and pharmacokinetics of an RNA-encoded T cell–engaging bispecific antibody targeting human claudin 6	52
Erratum for the Research Article “Boosting systemic absorption of peptides with a bioinspired buccal-stretching patch,” by Z. Luo et al .	52
Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease	52
Response to Comment on “Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases”	52
Preexisting immunity to the 2009 pandemic H1N1 virus reduces susceptibility to H5N1 infection and disease in ferrets	52
Predicting the next round of drugs for Medicare price negotiation	51
Antigen-Fc fusion therapy reduces severity of a model of pemphigus vulgaris without systemic immunosuppression	51
Targeting brain hubs of ictal fast ripple activity to reduce seizures in patients with drug-resistant epilepsy	50
An anti-mycobacterial conjugated oligoelectrolyte effective against Mycobacterium abscessus	50
Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy	50
Where do the pathogens that cause surgical site infections come from?	50
uPAR is highly expressed in recurrent glioblastoma and represents a candidate CAR T cell target	50
Cholesterol desensitizes the response of endometrial cancer to progestin by attenuating progestin signaling	50
A prM mutation that attenuates dengue virus replication in human cells enhances midgut infection in mosquitoes	50
A mouse model of chronic primary pain that integrates clinically relevant genetic vulnerability, stress, and minor injury	50
Vaccination with different group 2 influenza subtypes alters epitope targeting and breadth of hemagglutinin stem–specific human B cells	49
Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase	49
Donor-derived regulatory dendritic cell infusion modulates effector CD8+T cell and NK cell responses after liver transplantation	49
Provocateurs of autoimmunity within the gut microbiota	49
Learning CNS immunopathology from therapeutic interventions	49
Triple knockdown of CD11a , CD49d , and PSGL1 in T cells reduces CAR-T cell toxicity but preserves activity	48
Targeting SIRT2 induces MLH1 deficiency and boosts antitumor immunity in preclinical colorectal cancer models	48
Protein kinase Cι mediates immunosuppression in lung adenocarcinoma	48
Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease	48
Real-time in vivo analysis of murine β cells reveals autophagic flux defects before onset of autoimmune diabetes	48
Erratum for the Research Article “Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling”	48
Chemogenetics identifies separate area 25 brain circuits involved in anhedonia and anxiety in marmosets	48
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses	47
Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer	47
Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson’s disease	47
Activation and antitumor immunity of CD8 + T cells are supported by the glucose transporter GLUT10 and disrupted by lactic acid	47
Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human	47
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model	47
Urinary fluorogenic reporters for noninvasive detection and staging of kidney fibrosis	47
Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy	47
Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy	47
T cell responses to SARS-CoV-2 infection and vaccination are elevated in B cell deficiency and reduce risk of severe COVID-19	46
Hindbrain octadecaneuropeptide gliotransmission as a therapeutic target for energy balance control without nausea or emesis	46
Transient anti-interferon autoantibodies in the airways are associated with recovery from COVID-19	46
Erratum for the Research Article “Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia” by R. Sartori et al .	46
Neuronal population activity in the olivocerebellum encodes the frequency of essential tremor in mice and patients	46
Population-level implications of the Israeli booster campaign to curtail COVID-19 resurgence	46
An identity crisis for lung cancer cells	46
Human inner ear fluid imbalance detected by optical coherence tomography correlates with hearing loss	46
A new chapter in lipid signaling and kidney fibrosis	46
Targeting the PDE3B-cAMP-autophagy axis prevents liver injury in long-term supercooling liver preservation	45
Extracellular traps from myeloid cells as therapeutic targets in traumatic heterotopic ossification	45
Bruton’s tyrosine kinase inhibitors rescue neuronal impairment caused by B cell–mediated lymphotoxin-α release	45
Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency	45
Lactate transport inhibition therapeutically reprograms fibroblast metabolism in experimental pulmonary fibrosis	45
Eliminating interactions with the viral Fc receptor improves antibody-mediated protection against neonatal HSV infection in mice	45
A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers	45
Intrinsic connectivity of the human brain provides scaffold for tau aggregation in clinical variants of Alzheimer’s disease	45
The enhancer landscape predetermines the skeletal regeneration capacity of stromal cells	45
Response to Comment on “Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice”	45
Hemodynamic evaluation of biomaterial-based surgery for Tetralogy of Fallot using a biorobotic heart, in silico, and ovine models	44
Modeling lesion transition dynamics to clinically characterize patients with clade I mpox in the Democratic Republic of the Congo	44
PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections	44
Visualization of exhaled breath metabolites reveals distinct diagnostic signatures for acute cardiorespiratory breathlessness	44
Vaccines for a sustainable planet	44
The protein kinase C modulator bryostatin-1 therapeutically targets microglia to attenuate neuroinflammation and promote remyelination	44
Pharmacogenomic landscape of head and neck squamous cell carcinoma informs precision oncology therapy	43
BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML	43
Myeloid cell–specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease	43
Bone morphogenetic protein 9 is a candidate prognostic biomarker and host-directed therapy target for sepsis	43
TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure	43
CCR5 and CD74 are potential therapeutic targets for necroinflammation in preclinical cholesterol crystal embolism	43
A long-term image-derived AI-based risk model for primary prevention of breast cancer in individuals at high risk	43
Pathophysiology of Dyt1- Tor1a dystonia in mice is mediated by spinal neural circuit dysfunction	43