Science Translational Medicine

Papers
(The TQCC of Science Translational Medicine is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
In silico screening and preclinical validation identify bavisant as a therapeutic candidate for multiple sclerosis598
Integrated analysis of blood DNA methylation, genetic variants, circulating proteins, microRNAs, and kidney failure in type 1 diabetes351
A tale of two cells: Regulatory T cell–microglia cross-talk in the ischemic brain345
Increased brain microvascular hemoglobin concentrations in children with cerebral malaria271
Claudin-1 targeting suppresses tumor growth, invasion, and metastasis in patient-derived cholangiocarcinoma models263
Characterization of the SARS-CoV-2 B.1.621 (Mu) variant260
A protein-free vaccine stimulates innate immunity and protects against nosocomial pathogens237
Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment229
Podocyte YAP and TAZ hyperactivation drives glomerular epithelial proliferative diseases in mice and humans225
Germline-encoded recognition of peanut underlies development of convergent antibodies in humans221
Antigenic distance between primary and secondary dengue infections correlates with disease risk202
Advancing beyond the twists and turns of T cell exhaustion in cancer189
Tumor-specific antibodies elicited by engineered bacteria promote bladder cancer immunotherapy in preclinical mouse models186
Resilient nanostructured bioanalytic microneedle longitudinally monitors preclinical renal and hepatic drug clearance and dysfunction184
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome172
A first-in-human study of the fibroblast activation protein–targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors164
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery162
Evolution of inflammation and immunity in a dengue virus 1 human infection model162
Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging161
Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation161
Transcriptome-based identification of tumor-reactive and bystander CD8 + T cell receptor clonotypes in human pancreatic cancer152
Engineering CAR-T therapies for autoimmune disease and beyond151
Stronger regulation of AI in biomedicine145
AGER-dependent macropinocytosis drives resistance to KRAS-G12D–targeted therapy in advanced pancreatic cancer144
Targeting neurotumoral signaling networks in cancer143
A prefusion-stabilized RSV F subunit vaccine elicits B cell responses with greater breadth and potency than a postfusion F vaccine142
Combination bezafibrate and nivolumab treatment of patients with advanced non–small cell lung cancer141
Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms138
Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment138
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies134
TrkA-mediated sensory innervation of injured mouse tendon supports tendon sheath progenitor cell expansion and tendon repair134
In vivo gene immunotherapy for cancer133
SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8 + T cells129
Preclinical evaluation of antisense oligonucleotide therapy in a mouse model of HNRNPH2 -related neurodevelopmental disorder127
MEK1/2 inhibitors suppress pathological α-synuclein and neurotoxicity in cell models and a humanized mouse model of Parkinson’s disease124
Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation124
Systemic administration of an RNA binding and cell-penetrating antibody targets therapeutic RNA to multiple mouse models of cancer122
TREM1 activation of myeloid cells promotes antitumor immunity122
Sexually dimorphic differences in angiogenesis markers are associated with brain aging trajectories in humans122
Translating insights into therapies for Long Covid121
The pancreatic clock is a key determinant of pancreatic fibrosis progression and exocrine dysfunction120
Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis119
Development and preclinical validation of 2-deoxy 2-[ 18 F]fluorocellobiose as an Aspergillus -specific PET tracer118
The oncomodulin receptor ArmC10 enables axon regeneration in mice after nerve injury and neurite outgrowth in human iPSC–derived sensory neurons118
Repeated COVID-19 mRNA-based vaccination contributes to SARS-CoV-2 neutralizing antibody responses in the mucosa116
PET imaging of antisense oligonucleotide distribution in rat and nonhuman primate brains using click chemistry115
Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe114
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice114
Follistatin drives neuropathic pain in mice through IGF1R signaling in nociceptive neurons114
NAD + precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction113
FcγR-targeted tuftsin clusters rejuvenate macrophages in preclinical sepsis–associated secondary infection113
Improved control of a prosthetic limb by surgically creating electro-neuromuscular constructs with implanted electrodes109
Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma108
Chaperone-mediated autophagy supports organ regeneration and fibroblast quiescence in mouse models of fibrosis105
BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease102
A human histidyl-tRNA synthetase splice variant therapeutic targets NRP2 to resolve lung inflammation and fibrosis102
Generating functionally stable and antigen-specific T reg cells from effector T cells for cell therapy of inflammatory diseases102
The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipron101
Pseudomonas aeruginosa infection induces intragraft lymphocytotoxicity that triggers lung transplant antibody-mediated rejection101
Actin depolymerization promotes axon regeneration by restoring axonal mitochondrial transport in mouse models of optic neuropathy100
Molecular hallmarks of hydrocephalus98
Next-generation CAR T cell therapies for glioblastoma98
Found in translation—Fibrosis in metabolic dysfunction–associated steatohepatitis (MASH)98
Integrating the gut microbiome and pharmacology97
Rapid closure and hemostasis of ruptured soft tissues using a modified human tropoelastin-based sealant in preclinical models96
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer’s disease96
Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy96
Small-molecule inhibition of YTHDC1 as a strategy against acute myeloid leukemia in mouse models95
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment94
Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders93
T cell receptor precision editing of regulatory T cells for celiac disease93
CD23 + IgG1 + memory B cells are poised to switch to pathogenic IgE production in food allergy93
Farnesoid X receptor antagonizes macrophage-dependent licensing of effector T lymphocytes and progression of sclerosing cholangitis92
Extracellular BRICK1 drives heart repair after myocardial infarction in mice92
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria92
BDNF Val 66 Met protects oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer91
Adaptive cognitive control circuit changes associated with problem-solving ability and depression symptom outcomes over 24 months91
Leucine-rich α-2-glycoprotein 1 initiates the onset of diabetic retinopathy in mice90
Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer90
Calprotectin is a contributor to and potential therapeutic target for vascular calcification in chronic kidney disease89
The adenosine analog prodrug ATV006 is orally bioavailable and has preclinical efficacy against parental SARS-CoV-2 and variants89
Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice89
Wastewater surveillance facilitates climate change–resilient pathogen monitoring89
Harnessing regulatory T cells to establish immune tolerance89
Transferrin in combination with induction chemotherapy improves outcomes in mouse models of acute myeloid leukemia86
Clinicogenomic analysis of EGFR -mutant lung tumors identifies Rb pathway inactivation as a hallmark of squamous transformation86
IL-27–mediated hematopoietic dysregulation exacerbates disease severity in severe fever with thrombocytopenia syndrome virus infection84
Diet shapes the metabolite profile in the intact human ileum, which affects PYY release84
A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis83
Obesity and lifespan, a complex tango83
Short-course combination treatment for experimental chronic Chagas disease83
Erratum for the Research Article “Phase separation–based HTS identifies cobimetinib as a YAP-TEAD inhibitor that suppresses hyperactivated YAP-induced cancer progression”82
Anakinra restores immunological misfiring that drives influenza-associated pulmonary aspergillosis82
A nose for tau80
Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for Mycobacterium tuberculosis80
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria80
Assessment of cholesterol homeostasis in the living human brain80
Postoperative adhesions are abrogated by a sustained-release anti-JUN therapeutic in preclinical models79
Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration79
Mitochondrial augmentation of hematopoietic stem cells in children with single large-scale mitochondrial DNA deletion syndromes79
Cationic nanogel–based nasal therapeutic HPV vaccine prevents the development of cervical cancer78
The m 6 A demethylase FTO links TLR7 to mitochondrial oxidation driving age-associated B cell formation in systemic lupus erythematosus78
Neutralizing antibodies elicited in nonhuman primates by an enterovirus D68 virus-like particle vaccine target receptor binding sites78
Comparing antibody assays as correlates of protection against COVID-19 in the COVE mRNA-1273 vaccine efficacy trial77
Serial multiomics uncovers anti-glioblastoma responses not evident by routine clinical analyses77
Erratum for the Research Article “A functional identification platform reveals frequent, spontaneous neoantigen-specific T cell responses in patients with cancer” by A. M. Miller <76
Myeloid MAS–driven macrophage efferocytosis promotes resolution in ischemia-stressed mouse and human livers76
Historic 1994 influenza vaccine cohorts define breadth of antibody and B cell responses toward future influenza A and B viruses75
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins75
Multiomic analyses of longitudinal plasma samples identify thromboinflammation endotypes and trajectories in patients with trauma73
IgE in allergy: It takes two72
Sex, lean body mass, and cardiac performance72
Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia72
A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria72
A cross-talk established by tumor-targeted cytokines rescues CAR T cell activity and engages host T cells against glioblastoma in mice71
Targeting ryanodine receptor type 2 to mitigate chemotherapy-induced neurocognitive impairments in mice71
Lymphatic disruption drives lung transplant fibrosis through interleukin-1–mediated hyaluronan accumulation69
Clonal hematopoiesis detection in patients with cancer using cell-free DNA sequencing68
Targeting cytokines in inflammatory bowel disease68
Simultaneous analysis of mutations and methylations in circulating cell-free DNA for hepatocellular carcinoma detection68
Immune responses to gut bacteria associated with time to diagnosis and clinical response to T cell–directed therapy for type 1 diabetes prevention67
Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non–small cell lung cancer67
Inhibiting SLC38A2 lowers blood pressure in rodent models of hypertension67
Neurotensin receptor 2 agonism attenuates adverse cardiac remodeling in preclinical models66
Green light analgesia in mice is mediated by visual activation of enkephalinergic neurons in the ventrolateral geniculate nucleus66
A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis66
Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever virus infection65
Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases64
Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice64
Erratum for the Research Resource “Pharmacogenomic landscape of head and neck squamous cell carcinoma informs precision oncology therapy”63
Synthetic biology–driven induction of mature TLS formation enhances antitumor immunity in colorectal cancer63
MicroRNA-142-3p shuttling in extracellular vesicles marks regulatory T cell dysfunction in multiple sclerosis63
Metabolic surgery reduces CRC disease progression through circulating bile acid diversion63
Collagen V regulates renal function after kidney injury and can be pharmacologically targeted to enhance kidney repair in mice62
SARS-CoV-2 induces neutrophil degranulation and differentiation into myeloid-derived suppressor cells associated with severe COVID-1962
Cancer is embedded in a whole-body neural regulatory network62
NFIA regulates articular chondrocyte fatty acid metabolism and joint homeostasis62
An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans62
SV2A-PET imaging uncovers cortical synapse loss in multiple sclerosis62
T STEM -like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models62
Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation61
An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor61
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis61
Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice61
Translating the evolving molecular landscape of tumors to biomarkers of response for cancer immunotherapy61
Erratum for the Research Article “Platelet-derived growth factor C signaling is a potential therapeutic target for radiation proctopathy” by W. Lu et al 60
Erratum for the Research Article “Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4” by Y. Ren et al .60
Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis60
Expression of the excitatory opsin ChRERα can be traced longitudinally in rat and nonhuman primate brains with PET imaging59
Comment on “A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk”59
Genetic and structural aspects of amyloid diseases59
A germline SNP in BRMS1 predisposes patients with lung adenocarcinoma to metastasis and can be ameliorated by targeting c-fos58
Lowering the HTT1a transcript as an effective therapy for Huntington’s disease in a knockin mouse model58
Adeno-associated virus gene therapy–mediated CCR5 blockade suppresses virus replication long term in SHIV-infected macaques58
New government drug repurposing programs: Opportunities and uncertainties58
Design of a neutralizing and protective pan–encephalitic alphavirus receptor decoy protein58
Prostate tissue ablation and drug delivery by an image-guided injectable ionic liquid in ex vivo and in vivo models58
Flortaucipir PET uncovers relationships between tau and amyloid-β in primary age–related tauopathy and Alzheimer’s disease58
Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice57
A replicating RNA vaccine protects cynomolgus macaques against lethal clade 2.3.4.4b influenza A H5N1 virus challenge57
Genipin rescues developmental and degenerative defects in familial dysautonomia models and accelerates axon regeneration57
Seeking satiety: From signals to solutions57
Bioresponsive microneedle stent provides anastomosis and postoperative adjuvant therapy in preclinical resectable intestinal diseases56
Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer56
Blocking common γ chain cytokine signaling ameliorates T cell–mediated pathogenesis in disease models56
Human OX40L–CAR-T regs target activated antigen-presenting cells and control T cell alloreactivity55
Resident microbes shape the vaginal epithelial glycan landscape55
Cancer neuroscience: Mechanisms to medicine54
Neuroinflammation: An astrocyte perspective54
Preclinical efficacy and pharmacokinetics of an RNA-encoded T cell–engaging bispecific antibody targeting human claudin 653
Beta-blockade enhances anthracycline control of metastasis in triple-negative breast cancer53
Single-cell atlas of human infrapatellar fat pad and synovium implicates APOE signaling in osteoarthritis pathology53
Gastric dysfunction in patients with chronic nausea and vomiting syndromes defined by a noninvasive gastric mapping device52
Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheimer’s disease52
Long-term safety and efficacy of intracortical microstimulation in humans52
In vivo Bruton’s tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis52
Spatial genomics: Mapping the landscape of fibrosis51
Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β–mediated inflammation in mice and humans51
Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers51
Preexisting immunity to the 2009 pandemic H1N1 virus reduces susceptibility to H5N1 infection and disease in ferrets51
A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma51
Inhibition of MERTK reduces organ fibrosis in mouse models of fibrotic disease51
Repeated Omicron exposures redirect SARS-CoV-2–specific memory B cell evolution toward the latest variants51
Interleukin-2–based therapies in cancer50
Gut pathogen colonization precedes bloodstream infection in the neonatal intensive care unit50
Allergy: Mechanistic insights into new methods of prevention and therapy50
A peptide immunomodulator activates MST1 to expand and stabilize murine and human regulatory T cells for immune tolerance50
Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease50
Targeting Src reactivates pyroptosis to reverse chemoresistance in lung and pancreatic cancer models50
Antigen-Fc fusion therapy reduces severity of a model of pemphigus vulgaris without systemic immunosuppression49
An inactivated trivalent virion-based vaccine protects against aerosol challenge with encephalitic alphaviruses in mice and macaques49
Vaccination with different group 2 influenza subtypes alters epitope targeting and breadth of hemagglutinin stem–specific human B cells49
A prM mutation that attenuates dengue virus replication in human cells enhances midgut infection in mosquitoes49
Predicting the next round of drugs for Medicare price negotiation49
Erratum for the Research Article “Boosting systemic absorption of peptides with a bioinspired buccal-stretching patch,” by Z. Luo et al .49
Cholesterol desensitizes the response of endometrial cancer to progestin by attenuating progestin signaling49
Response to Comment on “Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases”49
Provocateurs of autoimmunity within the gut microbiota49
Where do the pathogens that cause surgical site infections come from?49
Real-time in vivo analysis of murine β cells reveals autophagic flux defects before onset of autoimmune diabetes48
Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase48
Urinary fluorogenic reporters for noninvasive detection and staging of kidney fibrosis48
Neuronal population activity in the olivocerebellum encodes the frequency of essential tremor in mice and patients48
T cell responses to SARS-CoV-2 infection and vaccination are elevated in B cell deficiency and reduce risk of severe COVID-1948
A mouse model of chronic primary pain that integrates clinically relevant genetic vulnerability, stress, and minor injury48
Erratum for the Research Article “Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling”48
Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy48
Donor-derived regulatory dendritic cell infusion modulates effector CD8+T cell and NK cell responses after liver transplantation47
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model47
Chemogenetics identifies separate area 25 brain circuits involved in anhedonia and anxiety in marmosets47
Activation and antitumor immunity of CD8 + T cells are supported by the glucose transporter GLUT10 and disrupted by lactic acid47
Triple knockdown of CD11a , CD49d , and PSGL1 in T cells reduces CAR-T cell toxicity but preserves activity47
uPAR is highly expressed in recurrent glioblastoma and represents a candidate CAR T cell target47
An anti-mycobacterial conjugated oligoelectrolyte effective against Mycobacterium abscessus47
Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease47
Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson’s disease47
Learning CNS immunopathology from therapeutic interventions47
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses47
Targeting SIRT2 induces MLH1 deficiency and boosts antitumor immunity in preclinical colorectal cancer models47
Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy47
Targeting brain hubs of ictal fast ripple activity to reduce seizures in patients with drug-resistant epilepsy47
Erratum for the Research Article “Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia” by R. Sartori et al .46
A new chapter in lipid signaling and kidney fibrosis46
Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer46
Protein kinase Cι mediates immunosuppression in lung adenocarcinoma46
Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human46
Human inner ear fluid imbalance detected by optical coherence tomography correlates with hearing loss46
The protein kinase C modulator bryostatin-1 therapeutically targets microglia to attenuate neuroinflammation and promote remyelination45
Vaccines for a sustainable planet45
Transient anti-interferon autoantibodies in the airways are associated with recovery from COVID-1945
Hemodynamic evaluation of biomaterial-based surgery for Tetralogy of Fallot using a biorobotic heart, in silico, and ovine models45
Bruton’s tyrosine kinase inhibitors rescue neuronal impairment caused by B cell–mediated lymphotoxin-α release45
CCR5 and CD74 are potential therapeutic targets for necroinflammation in preclinical cholesterol crystal embolism45
PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections45
Response to Comment on “Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice”45
Eliminating interactions with the viral Fc receptor improves antibody-mediated protection against neonatal HSV infection in mice44
A long-term image-derived AI-based risk model for primary prevention of breast cancer in individuals at high risk44
An integrated isothermal nucleic acid amplification test to detect HPV16 and HPV18 DNA in resource-limited settings44
Lactate transport inhibition therapeutically reprograms fibroblast metabolism in experimental pulmonary fibrosis44
A bioinspired mineralized collagen scaffold promotes enthesis healing and activates Gli1 expression in preclinical models43
Myeloid cell–specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease43
Modeling lesion transition dynamics to clinically characterize patients with clade I mpox in the Democratic Republic of the Congo43
Hindbrain octadecaneuropeptide gliotransmission as a therapeutic target for energy balance control without nausea or emesis43
Intrinsic connectivity of the human brain provides scaffold for tau aggregation in clinical variants of Alzheimer’s disease43
Increased β 2 -adrenergic signaling promotes fracture healing through callus neovascularization in mice43
The enhancer landscape predetermines the skeletal regeneration capacity of stromal cells43
Clinical validation of an HPV whole-genome sequencing assay for MRD detection in patients with HPV+ head and neck cancer treated with surgery43
Pharmacogenomic landscape of head and neck squamous cell carcinoma informs precision oncology therapy43
Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency43
HIF-2α drives hepatic Kupffer cell death and proinflammatory recruited macrophage activation in nonalcoholic steatohepatitis43
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