Science Translational Medicine

Papers
(The median citation count of Science Translational Medicine is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)
ArticleCitations
AGER-dependent macropinocytosis drives resistance to KRAS-G12D–targeted therapy in advanced pancreatic cancer532
Podocyte YAP and TAZ hyperactivation drives glomerular epithelial proliferative diseases in mice and humans435
A protein-free vaccine stimulates innate immunity and protects against nosocomial pathogens338
TrkA-mediated sensory innervation of injured mouse tendon supports tendon sheath progenitor cell expansion and tendon repair297
Antigenic distance between primary and secondary dengue infections correlates with disease risk252
Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting236
Combination bezafibrate and nivolumab treatment of patients with advanced non–small cell lung cancer224
Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment223
Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice210
Transcriptome-based identification of tumor-reactive and bystander CD8 + T cell receptor clonotypes in human pancreatic cancer205
A first-in-human study of the fibroblast activation protein–targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors202
Stronger regulation of AI in biomedicine200
A tale of two cells: Regulatory T cell–microglia cross-talk in the ischemic brain199
Integrated analysis of blood DNA methylation, genetic variants, circulating proteins, microRNAs, and kidney failure in type 1 diabetes198
Germline-encoded recognition of peanut underlies development of convergent antibodies in humans197
Increased brain microvascular hemoglobin concentrations in children with cerebral malaria194
A risk model for digital breast tomosynthesis to predict breast cancer and guide clinical care191
Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging191
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies183
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery167
Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection166
Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment162
Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms159
Point-of-care diagnostic tests for tuberculosis disease157
Characterization of the SARS-CoV-2 B.1.621 (Mu) variant156
The rapid replacement of the SARS-CoV-2 Delta variant by Omicron (B.1.1.529) in England155
Advancing beyond the twists and turns of T cell exhaustion in cancer152
SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8 + T cells151
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome148
Engineering CAR-T therapies for autoimmune disease and beyond147
A prefusion-stabilized RSV F subunit vaccine elicits B cell responses with greater breadth and potency than a postfusion F vaccine144
In vivo gene immunotherapy for cancer143
Evolution of inflammation and immunity in a dengue virus 1 human infection model141
Metabolic reprogramming of skeletal muscle by resident macrophages points to CSF1R inhibitors as muscular dystrophy therapeutics139
Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation138
A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer135
Development and preclinical validation of 2-deoxy 2-[ 18 F]fluorocellobiose as an Aspergillus -specific PET tracer129
A human histidyl-tRNA synthetase splice variant therapeutic targets NRP2 to resolve lung inflammation and fibrosis129
Erratum for the Research Article: “The Role of Dimethylarginine Dimethylaminohydrolase in Idiopathic Pulmonary Fibrosis” by S. S. Pullamsetti, R. Savai, R. Dumitrascu, B. K. Dahal, J. Wilhelm, M. Koni128
Repeated COVID-19 mRNA-based vaccination contributes to SARS-CoV-2 neutralizing antibody responses in the mucosa121
Improved control of a prosthetic limb by surgically creating electro-neuromuscular constructs with implanted electrodes118
NAD + precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction118
Follistatin drives neuropathic pain in mice through IGF1R signaling in nociceptive neurons118
PET imaging of antisense oligonucleotide distribution in rat and nonhuman primate brains using click chemistry118
Rapid closure and hemostasis of ruptured soft tissues using a modified human tropoelastin-based sealant in preclinical models116
Systemic administration of an RNA binding and cell-penetrating antibody targets therapeutic RNA to multiple mouse models of cancer115
Translating insights into therapies for Long Covid113
The oncomodulin receptor ArmC10 enables axon regeneration in mice after nerve injury and neurite outgrowth in human iPSC–derived sensory neurons113
Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models111
Found in translation—Fibrosis in metabolic dysfunction–associated steatohepatitis (MASH)110
Genomic and epigenomic BRCA alterations predict adaptive resistance and response to platinum-based therapy in patients with triple-negative breast and ovarian carcinomas110
Pseudomonas aeruginosa infection induces intragraft lymphocytotoxicity that triggers lung transplant antibody-mediated rejection109
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager109
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia108
Targeting AKR1B1 inhibits glutathione de novo synthesis to overcome acquired resistance to EGFR-targeted therapy in lung cancer107
Next-generation CAR T cell therapies for glioblastoma107
Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting107
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice106
The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipron106
BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease106
Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis106
TREM1 activation of myeloid cells promotes antitumor immunity105
Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe104
The pancreatic clock is a key determinant of pancreatic fibrosis progression and exocrine dysfunction103
Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation101
Molecular hallmarks of hydrocephalus101
MEK1/2 inhibitors suppress pathological α-synuclein and neurotoxicity in cell models and a humanized mouse model of Parkinson’s disease100
Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation100
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer’s disease100
Sexually dimorphic differences in angiogenesis markers are associated with brain aging trajectories in humans98
Integrating the gut microbiome and pharmacology98
Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy98
Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer97
Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors97
T cell receptor precision editing of regulatory T cells for celiac disease96
A nose for tau96
Harnessing regulatory T cells to establish immune tolerance96
A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis94
Calprotectin is a contributor to and potential therapeutic target for vascular calcification in chronic kidney disease94
Adaptive cognitive control circuit changes associated with problem-solving ability and depression symptom outcomes over 24 months94
Myeloid MAS–driven macrophage efferocytosis promotes resolution in ischemia-stressed mouse and human livers94
Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice93
Diet shapes the metabolite profile in the intact human ileum, which affects PYY release93
The adenosine analog prodrug ATV006 is orally bioavailable and has preclinical efficacy against parental SARS-CoV-2 and variants93
Astrocytic α2-Na + /K + ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model92
Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders92
Obesity and lifespan, a complex tango91
Comparing antibody assays as correlates of protection against COVID-19 in the COVE mRNA-1273 vaccine efficacy trial91
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment89
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria89
Mitochondrial augmentation of hematopoietic stem cells in children with single large-scale mitochondrial DNA deletion syndromes88
Farnesoid X receptor antagonizes macrophage-dependent licensing of effector T lymphocytes and progression of sclerosing cholangitis88
CD23 + IgG1 + memory B cells are poised to switch to pathogenic IgE production in food allergy87
Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for Mycobacterium tuberculosis87
Wastewater surveillance facilitates climate change–resilient pathogen monitoring87
Short-course combination treatment for experimental chronic Chagas disease87
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria86
Ebola virus persistence and disease recrudescence in the brains of antibody-treated nonhuman primate survivors86
Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire85
Postoperative adhesions are abrogated by a sustained-release anti-JUN therapeutic in preclinical models84
Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort84
AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein–specific T H 1 response with a diverse TCR repertoire84
Assessment of cholesterol homeostasis in the living human brain84
Innate PD-L1 limits T cell–mediated adipose tissue inflammation and ameliorates diet-induced obesity83
Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration83
A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis83
Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non–small cell lung cancer82
Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice81
NFIA regulates articular chondrocyte fatty acid metabolism and joint homeostasis81
MicroRNA-142-3p shuttling in extracellular vesicles marks regulatory T cell dysfunction in multiple sclerosis80
A cross-talk established by tumor-targeted cytokines rescues CAR T cell activity and engages host T cells against glioblastoma in mice80
Targeting ryanodine receptor type 2 to mitigate chemotherapy-induced neurocognitive impairments in mice79
Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice79
Albumin nanoparticle containing a PI3Kγ inhibitor and paclitaxel in combination with α-PD1 induces tumor remission of breast cancer in mice78
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins78
SARS-CoV-2 induces neutrophil degranulation and differentiation into myeloid-derived suppressor cells associated with severe COVID-1978
IgE in allergy: It takes two77
Immune responses to gut bacteria associated with time to diagnosis and clinical response to T cell–directed therapy for type 1 diabetes prevention76
Inhibiting SLC38A2 lowers blood pressure in rodent models of hypertension76
Erratum for the Research Article “A functional identification platform reveals frequent, spontaneous neoantigen-specific T cell responses in patients with cancer” by A. M. Miller et al<76
Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers76
Sex, lean body mass, and cardiac performance75
Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases75
Collagen V regulates renal function after kidney injury and can be pharmacologically targeted to enhance kidney repair in mice75
Metabolic surgery reduces CRC disease progression through circulating bile acid diversion75
Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia74
Clonal hematopoiesis detection in patients with cancer using cell-free DNA sequencing74
Synthetic biology–driven induction of mature TLS formation enhances antitumor immunity in colorectal cancer74
Antibody-mediated prevention of vaginal HIV transmission is dictated by IgG subclass in humanized mice74
Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation74
Tissue-resident CD8 + T cells drive compartmentalized and chronic autoimmune damage against CNS neurons73
A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria73
Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair72
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis72
Targeting cytokines in inflammatory bowel disease72
Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever virus infection71
An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor71
T STEM -like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models71
An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans70
Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis70
Development of ICT01, a first-in-class, anti-BTN3A antibody for activating Vγ9Vδ2 T cell–mediated antitumor immune response69
MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases69
Antibody Fc characteristics and effector functions correlate with protection from symptomatic dengue virus type 3 infection69
Translating the evolving molecular landscape of tumors to biomarkers of response for cancer immunotherapy68
Simultaneous analysis of mutations and methylations in circulating cell-free DNA for hepatocellular carcinoma detection67
Green light analgesia in mice is mediated by visual activation of enkephalinergic neurons in the ventrolateral geniculate nucleus67
SV2A-PET imaging uncovers cortical synapse loss in multiple sclerosis67
Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice66
Blocking common γ chain cytokine signaling ameliorates T cell–mediated pathogenesis in disease models66
A germline SNP in BRMS1 predisposes patients with lung adenocarcinoma to metastasis and can be ameliorated by targeting c-fos66
Erratum for the Research Article: “Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses” by E. A. Bordt, L. L. Shook, C. Atyeo, K. M. Pullen, R. M. De Guzman, M.-C. Mein66
Spatial genomics: Mapping the landscape of fibrosis66
Erratum for the Research Article “Platelet-derived growth factor C signaling is a potential therapeutic target for radiation proctopathy” by W. Lu et al .66
Comment on “A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk”66
In vivo Bruton’s tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis65
Delivery of therapeutic carbon monoxide by gas-entrapping materials65
Expression of the excitatory opsin ChRERα can be traced longitudinally in rat and nonhuman primate brains with PET imaging65
Seeking satiety: From signals to solutions65
Genipin rescues developmental and degenerative defects in familial dysautonomia models and accelerates axon regeneration64
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection64
An AAV gene therapy computes over multiple cellular inputs to enable precise targeting of multifocal hepatocellular carcinoma in mice64
Allergy: Mechanistic insights into new methods of prevention and therapy64
Flortaucipir PET uncovers relationships between tau and amyloid-β in primary age–related tauopathy and Alzheimer’s disease64
Preclinical efficacy and pharmacokinetics of an RNA-encoded T cell–engaging bispecific antibody targeting human claudin 663
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due toTTNmutations63
Neuroinflammation: An astrocyte perspective63
A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma63
Gut pathogen colonization precedes bloodstream infection in the neonatal intensive care unit62
Erratum for the Research Article “Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4” by Y. Ren et al .62
Interleukin-2–based therapies in cancer62
Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers61
Resident microbes shape the vaginal epithelial glycan landscape61
New government drug repurposing programs: Opportunities and uncertainties61
Gastric dysfunction in patients with chronic nausea and vomiting syndromes defined by a noninvasive gastric mapping device60
Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases60
Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-1960
Prostate tissue ablation and drug delivery by an image-guided injectable ionic liquid in ex vivo and in vivo models60
Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheimer’s disease60
Preexisting immunity to the 2009 pandemic H1N1 virus reduces susceptibility to H5N1 infection and disease in ferrets59
Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer59
Beta-blockade enhances anthracycline control of metastasis in triple-negative breast cancer59
Human OX40L–CAR-T regs target activated antigen-presenting cells and control T cell alloreactivity59
Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β–mediated inflammation in mice and humans59
Dynamic PET-facilitated modeling and high-dose rifampin regimens for Staphylococcus aureus orthopedic implant–associated infections59
Inhibition of MERTK reduces organ fibrosis in mouse models of fibrotic disease59
Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease58
Targeting Src reactivates pyroptosis to reverse chemoresistance in lung and pancreatic cancer models58
Repeated Omicron exposures redirect SARS-CoV-2–specific memory B cell evolution toward the latest variants57
NF-κB perturbation reveals unique immunomodulatory functions in Prx1 + fibroblasts that promote development of atopic dermatitis57
Single-cell atlas of human infrapatellar fat pad and synovium implicates APOE signaling in osteoarthritis pathology57
Alterations of human skin microbiome and expansion of antimicrobial resistance after systemic antibiotics56
Genetic and structural aspects of amyloid diseases56
Neuronal population activity in the olivocerebellum encodes the frequency of essential tremor in mice and patients56
Triple knockdown of CD11a , CD49d , and PSGL1 in T cells reduces CAR-T cell toxicity but preserves activity56
Antigen-Fc fusion therapy reduces severity of a model of pemphigus vulgaris without systemic immunosuppression56
Chemogenetics identifies separate area 25 brain circuits involved in anhedonia and anxiety in marmosets55
A mouse model of chronic primary pain that integrates clinically relevant genetic vulnerability, stress, and minor injury55
Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy55
Provocateurs of autoimmunity within the gut microbiota55
Targeting SIRT2 induces MLH1 deficiency and boosts antitumor immunity in preclinical colorectal cancer models55
Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase55
Donor-derived regulatory dendritic cell infusion modulates effector CD8+T cell and NK cell responses after liver transplantation55
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model55
An anti-mycobacterial conjugated oligoelectrolyte effective against Mycobacterium abscessus55
Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy55
Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease54
Response to Comment on “Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases”54
Global spatial dynamics and vaccine-induced fitness changes of Bordetella pertussis54
Glutamine promotes antibiotic uptake to kill multidrug-resistant uropathogenic bacteria54
GABABreceptor modulation of visual sensory processing in adults with and without autism spectrum disorder54
A homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2–specific immune responses in rhesus macaques54
T cell responses to SARS-CoV-2 infection and vaccination are elevated in B cell deficiency and reduce risk of severe COVID-1953
Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy53
Response to comment on “Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics”52
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses52
A prM mutation that attenuates dengue virus replication in human cells enhances midgut infection in mosquitoes52
Predicting the next round of drugs for Medicare price negotiation52
Alpelisib administration reduced lymphatic malformations in a mouse model and in patients52
Erratum for the Research Article “Boosting systemic absorption of peptides with a bioinspired buccal-stretching patch,” by Z. Luo et al .51
Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer51
Protein kinase Cι mediates immunosuppression in lung adenocarcinoma51
Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human51
Where do the pathogens that cause surgical site infections come from?51
Learning CNS immunopathology from therapeutic interventions51
Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson’s disease50
Vaccination with different group 2 influenza subtypes alters epitope targeting and breadth of hemagglutinin stem–specific human B cells50
Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected49
An inactivated trivalent virion-based vaccine protects against aerosol challenge with encephalitic alphaviruses in mice and macaques49
Vaccines for a sustainable planet49
Activation and antitumor immunity of CD8 + T cells are supported by the glucose transporter GLUT10 and disrupted by lactic acid49
Hindbrain octadecaneuropeptide gliotransmission as a therapeutic target for energy balance control without nausea or emesis49
Modeling lesion transition dynamics to clinically characterize patients with clade I mpox in the Democratic Republic of the Congo49
Cholesterol desensitizes the response of endometrial cancer to progestin by attenuating progestin signaling49
Human inner ear fluid imbalance detected by optical coherence tomography correlates with hearing loss49
A new chapter in lipid signaling and kidney fibrosis48
A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers48
Intrinsic connectivity of the human brain provides scaffold for tau aggregation in clinical variants of Alzheimer’s disease48
Response to Comment on “Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice”48
Hemodynamic evaluation of biomaterial-based surgery for Tetralogy of Fallot using a biorobotic heart, in silico, and ovine models48
Pathophysiology of Dyt1- Tor1a dystonia in mice is mediated by spinal neural circuit dysfunction47
Erratum for the Research Article “Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia” by R. Sartori et al .47
Guanosine diphosphate–mannose suppresses homologous recombination repair and potentiates antitumor immunity in triple-negative breast cancer47
Keratinocytes: From passive targets to active mediators of systemic autoimmunity47
BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML47
An identity crisis for lung cancer cells47
DeepHeme, a high-performance, generalizable deep ensemble for bone marrow morphometry and hematologic diagnosis47
PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections47
Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency47
TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure46
Increased β 2 -adrenergic signaling promotes fracture healing through callus neovascularization in mice46
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