Science Translational Medicine

Article	Citations
IgA dominates the early neutralizing antibody response to SARS-CoV-2	802
Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19	488
A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples	487
Enhanced SARS-CoV-2 neutralization by dimeric IgA	371
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates	335
COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters	334
Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients	291
Importance of the pig as a human biomedical model	286
A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus	250
Lung transplantation for patients with severe COVID-19	240
SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma	237
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis	222
A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations	221
Advanced bandages for diabetic wound healing	215
Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndrome	197
Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection	196
Prospects for a safe COVID-19 vaccine	193
Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2	188
3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV–infected mice	185
Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance	184
Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors	181
Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice	181
The past, present, and future of antibiotics	181
An Alphavirus -derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates	177
Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits	170

Sampling interstitial fluid from human skin using a microneedle patch	168
Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces viral shedding after SARS-CoV-2 D614G challenge in preclinical models	164
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19	161
Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals	158
Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection	157
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages	156
Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide	154
Bioadhesive hydrogels demonstrating pH-independent and ultrafast gelation promote gastric ulcer healing in pigs	154
A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma	154
Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy	153
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia	152
The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans	148
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity	144
Gut microbiota dysbiosis and altered tryptophan catabolism contribute to autoimmunity in lupus-susceptible mice	144
Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19	143
Effective combination immunotherapy using oncolytic viruses to deliver CAR targets to solid tumors	143
Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome	142
siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice	141
iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti–PD-1 therapy	141
Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in lungs of African green monkeys	139
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery	135
Acute inflammatory response via neutrophil activation protects against the development of chronic pain	134
Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy	132
T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals	130
Reproducibility in machine learning for health research: Still a ways to go	128
Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy	125
Exosomes secreted by hiPSC-derived cardiac cells improve recovery from myocardial infarction in swine	124
In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer’s disease pathology and cognitive decline	122
Antitumor activity without on-target off-tumor toxicity of GD2–chimeric antigen receptor T cells in patients with neuroblastoma	122
Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines	121
Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases	121
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection	121
Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms	121
Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models	119
PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity	119
Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease	119
Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils	118
Smartwatch inertial sensors continuously monitor real-world motor fluctuations in Parkinson’s disease	117
The cortical origin and initial spread of medial temporal tauopathy in Alzheimer’s disease assessed with positron emission tomography	116
SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19	116
SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor activity in mouse models	115
C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy	114
Nicotinamide for the treatment of heart failure with preserved ejection fraction	113
Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms	113
Reprogramming lipid metabolism prevents effector T cell senescence and enhances tumor immunotherapy	111
A second X chromosome contributes to resilience in a mouse model of Alzheimer’s disease	110
Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses	109
Predicting the mutational drivers of future SARS-CoV-2 variants of concern	109
Toward robust mammography-based models for breast cancer risk	109
Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation	107

Chi3l1 /YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer’s disease pathogenesis	107
Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade	105
Lung and gut microbiota are altered by hyperoxia and contribute to oxygen-induced lung injury in mice	104
Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy	104
MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates	104
DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia	104
Undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the United States	103
Exercise-induced piezoelectric stimulation for cartilage regeneration in rabbits	103
mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions	102
Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination	101
Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment	101
Donor fecal microbiota transplantation ameliorates intestinal graft-versus-host disease in allogeneic hematopoietic cell transplant recipients	101
A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components	99
A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles	98
Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models	96
Delivery mode and gut microbial changes correlate with an increased risk of childhood asthma	96
Combination of metabolic intervention and T cell therapy enhances solid tumor immunotherapy	95
Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates	95
Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair	94
Granzyme K + CD8 T cells form a core population in inflamed human tissue	94
Wireless sensors for continuous, multimodal measurements at the skin interface with lower limb prostheses	94
Intracavity generation of glioma stem cell–specific CAR macrophages primes locoregional immunity for postoperative glioblastoma therapy	94
Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells	94
MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases	93
Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses	92
Targeting cartilage EGFR pathway for osteoarthritis treatment	91
Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy	89
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease	88
Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor	88
A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice	88
Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset	87
Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses	87
Omicron variant Spike-specific antibody binding and Fc activity are preserved in recipients of mRNA or inactivated COVID-19 vaccines	87
Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury	87
CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice	87
Predicting functional effects of missense variants in voltage-gated sodium and calcium channels	85
Using deep learning for dermatologist-level detection of suspicious pigmented skin lesions from wide-field images	85
An off-the-shelf bioadhesive patch for sutureless repair of gastrointestinal defects	85
In vivo prime editing of a metabolic liver disease in mice	83
A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence	83
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern	83
Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma	82
Trispecific CD19-CD20-CD22–targeting duoCAR-T cells eliminate antigen-heterogeneous B cell tumors in preclinical models	82
A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models	82
Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans	81
Oncolytic virus–mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice	81
Glutamine promotes antibiotic uptake to kill multidrug-resistant uropathogenic bacteria	81
MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation	81
An oral antisense oligonucleotide for PCSK9 inhibition	80
Brain circuits for pain and its treatment	80
APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function	80
A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates	80
mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent	79
Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models	79
AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein–specific T H 1 response with a diverse TCR repertoire	77
A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes	77
Immunocytokines are a promising immunotherapeutic approach against glioblastoma	77
Cellular senescence impairs the reversibility of pulmonary arterial hypertension	76
Soft, skin-interfaced sweat stickers for cystic fibrosis diagnosis and management	76
Using influenza surveillance networks to estimate state-specific prevalence of SARS-CoV-2 in the United States	76
An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer’s disease	76
Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity	75
Key epidemiological drivers and impact of interventions in the 2020 SARS-CoV-2 epidemic in England	75
COVID-19 mRNA vaccines drive differential antibody Fc-functional profiles in pregnant, lactating, and nonpregnant women	75
Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment	74
Lung cancer scRNA-seq and lipidomics reveal aberrant lipid metabolism for early-stage diagnosis	74
Extracellular vesicles deposit PCNA to rejuvenate aged bone marrow–derived mesenchymal stem cells and slow age-related degeneration	74
Cardiac ryanodine receptor calcium release deficiency syndrome	73
Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans	72
Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition	72
Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort	72
Gene therapy knockdown of Hippo signaling induces cardiomyocyte renewal in pigs after myocardial infarction	72
Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity	72
SARS-CoV-2 BA.1 variant is neutralized by vaccine booster–elicited serum but evades most convalescent serum and therapeutic antibodies	71
Stereotypic neutralizing V H antibodies against SARS-CoV-2 spike protein receptor binding domain in patients with COVID-19 and healthy individuals	71
Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS	71
Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice	71
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice	70
Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip	70
Academic careers and the COVID-19 pandemic: Reversing the tide	70

SARS-CoV-2 3CL pro mutations selected in a VSV-based system confer resistance to nirmatrelvir, ensitrelvir, and GC376	70
Therapeutic responses to Roseomonas mucosa in atopic dermatitis may involve lipid-mediated TNF-related epithelial repair	69
A high-throughput cell- and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma	69
A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma	69
Mutant huntingtin and neurofilament light have distinct longitudinal dynamics in Huntington’s disease	68
Staphylococcus Agr virulence is critical for epidermal colonization and associates with atopic dermatitis development	68
A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia	68
Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models	67
Long-lasting analgesia via targeted in situ repression of Na V 1.7 in mice	67
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations	67
Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche	67
Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers	67
Persistent post–COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium	67
Druggable cancer phosphatases	66
Chimeric STAR receptors using TCR machinery mediate robust responses against solid tumors	66
Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19	66
Activation of NRF2 ameliorates oxidative stress and cystogenesis in autosomal dominant polycystic kidney disease	66
Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia	65
SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies	65
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis	65
Blockade of the CD93 pathway normalizes tumor vasculature to facilitate drug delivery and immunotherapy	65
Citrullinated vimentin mediates development and progression of lung fibrosis	65
Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum	65
Bimodal neuromodulation combining sound and tongue stimulation reduces tinnitus symptoms in a large randomized clinical study	65
Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model	65
Platelets release mitochondrial antigens in systemic lupus erythematosus	65
Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host disease	64
A probiotic yeast-based immunotherapy against Clostridioides difficile infection	64
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia	64
Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade	64
Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro	63
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling	63
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis	63
Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation	62
CECR2 drives breast cancer metastasis by promoting NF-κB signaling and macrophage-mediated immune suppression	62
Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA	62
Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy	61
Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis	61
AD-linked R47H- TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation	61
Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease	61
Transplanted microvessels improve pluripotent stem cell–derived cardiomyocyte engraftment and cardiac function after infarction in rats	61
SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice	61
Development and deployment of COVID-19 vaccines for those most vulnerable	60
SARS-CoV-2 infection drives an inflammatory response in human adipose tissue through infection of adipocytes and macrophages	60
A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults	60
A microRNA-21–mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis	59
A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models	59
Cardiosphere-derived exosomal microRNAs for myocardial repair in pediatric dilated cardiomyopathy	59
A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression	59
Elastin-like recombinamers-based hydrogel modulates post-ischemic remodeling in a non-transmural myocardial infarction in sheep	59
Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies	58
LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade	58
De novo prediction of cancer-associated T cell receptors for noninvasive cancer detection	58
Oligodendrocyte-derived extracellular vesicles as antigen-specific therapy for autoimmune neuroinflammation in mice	58
An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice	57
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia	57
Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair	57
Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses	57
A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters	57
Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests	57
Risk assessment with gut microbiome and metabolite markers in NAFLD development	56
TRIB3 reduces CD8 + T cell infiltration and induces immune evasion by repressing the STAT1-CXCL10 axis in colorectal cancer	56
Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption	56
Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy	56
Depleting plasmacytoid dendritic cells reduces local type I interferon responses and disease activity in patients with cutaneous lupus	56
Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin	56
scRNA-seq of human vitiligo reveals complex networks of subclinical immune activation and a role for CCR5 in T reg function	56
Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype	56
Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents	56
Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer’s disease	55
Human brain mapping with multithousand-channel PtNRGrids resolves spatiotemporal dynamics	55
Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis	55
Mitochondrial metabolic reprogramming controls the induction of immunogenic cell death and efficacy of chemotherapy in bladder cancer	55
Attenuation of peripheral serotonin inhibits tumor growth and enhances immune checkpoint blockade therapy in murine tumor models	55
Plasma neurofilament light predicts mortality in patients with stroke	55
LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies	55
Targeted inhibition of PI3 kinase/mTOR specifically in fibrotic lung fibroblasts suppresses pulmonary fibrosis in experimental models	54
Intratumoral nanoplexed poly I:C BO-112 in combination with systemic anti–PD-1 for patients with anti–PD-1–refractory tumors	54
Development of ICT01, a first-in-class, anti-BTN3A antibody for activating Vγ9Vδ2 T cell–mediated antitumor immune response	54
Mechanism and reversal of drug-induced nephrotoxicity on a chip	54
Interleukin-2 signals converge in a lymphoid–dendritic cell pathway that promotes anticancer immunity	53
Mechanism of praziquantel action at a parasitic flatworm ion channel	53
Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers	53
Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel	53
CD4 + T cells are essential for the development of destructive thyroiditis induced by anti–PD-1 antibody in thyroglobulin-immunized mice	53
Receptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different species	53
Treatment of a genetic brain disease by CNS-wide microglia replacement	53
Necrotizing enterocolitis induces T lymphocyte–mediated injury in the developing mammalian brain	52
Systemic cancer therapy with engineered adenovirus that evades innate immunity	52
Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates	52
Infection or a third dose of mRNA vaccine elicits neutralizing antibody responses against SARS-CoV-2 in kidney transplant recipients	52
Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase	52
Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy	52
A chimeric antigen receptor with antigen-independent OX40 signaling mediates potent antitumor activity	52
A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer	52