Aging-US

Article	Citations
	292
Causal role of immune cells in prostate cancer: a bidirectional Mendelian-randomization analyses	179
Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma	128
PUS1 is a novel biomarker for evaluating malignancy of human renal cell carcinoma	98
Identification of circRNA-miRNA-mRNA networks to explore the molecular mechanism and immune regulation of postoperative neurocognitive disorder	67
Comprehensive analysis of integrin αvβ3/α6β1 in prognosis and immune escape of prostate cancer	59
In vivo tau staging in Alzheimer’s disease	57
Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer	55
CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction	50
S100A9, as a potential predictor of prognosis and immunotherapy response for GBM, promotes the malignant progression of GBM cells and migration of M2 macrophages	50
Association between dipeptidyl peptidase-4 inhibitor use and risk of Parkinson’s disease among patients with diabetes mellitus: a retrospective cohort study	48
Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies	47
Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma	47
DNA methylation entropy is a biomarker for aging	47
THY1 is a prognostic-related biomarker via mediating immune infiltration in lung squamous cell carcinoma (LUSC)	46
Identification and validation of immunogenic cell death-related score in uveal melanoma to improve prediction of prognosis and response to immunotherapy	46
Development and validation of a combined cuproptosis and immunogenic cell death prognostic model for diffuse large B-cell lymphoma	45
AR12 increases BAG3 expression which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy	45
Unraveling the unfolded protein response signature: implications for tumor immune microenvironment heterogeneity and clinical prognosis in stomach cancer	44
The potential benefit of metformin to reduce delirium risk and mortality: a retrospective cohort study	44
Two lncRNA signatures with cuproptosis as a novel prognostic model and clinicopathological value for endometrioid endometrial adenocarcinoma	43
Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC	43
Multilevel data integration and molecular docking approach to systematically elucidate the underlying pharmacological mechanisms of Er-Zhi-Wan against hepatocellular carcinoma	42
Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence	42
Brief, weekly magnetic muscle therapy improves mobility and lean body mass in older adults: a Southeast Asia community case study	42

Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats	40
Potential reversal of biological age in women following an 8-week methylation-supportive diet and lifestyle program: a case series	39
Serum adenosine deaminase activity and acute cerebral infarction: a retrospective case-control study based on 7913 participants	39
Organotypic cultures as aging associated disease models	38
Correction: Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial	37
Interleukin-17D promotes lung cancer progression by inducing tumor-associated macrophage infiltration via the p38 MAPK signaling pathway	37
An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis	36
Inhibition of BACE1 attenuates microglia-induced neuroinflammation after intracerebral hemorrhage by suppressing STAT3 activation	35
Identification and validation of oxeiptosis-associated lncRNAs and prognosis-related signature genes to predict the immune status in uterine corpus endometrial carcinoma	35
LncRNA DANCR suppresses acute myocardial infarction in mice via mediating p-RXRA/TRAF2/NIK/IKK/NF-κB signaling pathway	34
Ferulic acid ameliorates the quality of in vitro-aged bovine oocytes by suppressing oxidative stress and apoptosis	34
Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results	34
Mapping the core senescence phenotype of primary human colon fibroblasts	34
BMAL1 modulates senescence programming via AP-1	32
Pan-cancer analysis of disulfidptosis with potential implications in prognosis, immune microenvironment, and drug resistance in human cancer	32
Epigenetic aging signatures and age prediction in human skeletal muscle	32
Investigating causal associations among gut microbiota, gut microbiota-derived metabolites, and gestational diabetes mellitus: a bidirectional Mendelian randomization study	31
Identification of VEGFs-related gene signature for predicting microangiogenesis and hepatocellular carcinoma prognosis	31
Elderly CD8+ T cells in the focus for immunotherapeutic approaches	30
Development of a prognostic model based on anoikis-related genes for predicting clinical prognosis and immunotherapy of hepatocellular carcinoma	30
The rodent aging interventions database (RAID): a data visualization tool for all studies reporting rodent lifespan extension	30
Age, sex, and mitochondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat model	29
FAM46C-mediated tumor heterogeneity predicts extramedullary metastasis and poorer survival in multiple myeloma	29
A neural network model was constructed by screening the potential biomarkers of aortic dissection based on genes associated with pyroptosis	29
Correction for: Sonic hedgehog signaling promotes angiogenesis of endothelial progenitor cells to improve pressure ulcers healing by PI3K/AKT/eNOS signaling	29
Growth hormone excess drives liver aging via increased glycation stress	28
Prognostic significance and immune characteristics of GPR27 in gastric cancer	28
Development and validation of a novel model for predicting the survival of bladder cancer based on ferroptosis-related genes	28
Physical fitness and lifestyles associated with biological aging	28
Machine learning constructs a T cell-related signature for predicting prognosis and drug sensitivity in ovarian cancer	28
Hairy gene homolog increases nasopharyngeal carcinoma cell stemness by upregulating Bmi-1	28
On the lifespan of Enchytraeus crypticus - impact of iron (nanomaterial and salt) on aging	28
Novel insights into the regulatory role of N6-methyladenosine methylation modified autophagy in sepsis	27
Correction for: circACTA2 mediates Ang II-induced VSMC senescence by modulation of the interaction of ILF3 with CDK4 mRNA	27
Identification and validation of an anoikis-related genes signature for prognostic implication in papillary thyroid cancer	27
Associations between serum total cholesterol level and bone mineral density in older adults	27
HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis	27
Isoaspartate and neurodegeneration	27
Retraction of: Extracellular vesicle derived miR-544 downregulates expression of tumor suppressor promyelocytic leukemia zinc finger resulting in increased peritoneal metastasis in gastric cancer	27
Integrative analysis of single-cell and bulk RNA sequencing unveils the senescence landscape in ischemic stroke	27
Ros-mediated mitochondrial oxidative stress is involved in the ameliorating effect of ginsenoside GSLS on chlorpyrifos-induced hepatotoxicity in mice	27
Combination of 7-O-geranylquercetin and microRNA-451 enhances antitumor effect of Adriamycin by reserving P-gp-mediated drug resistance in breast cancer	26
Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome	26
Human adipose-derived stem cells preconditioned with a novel herbal formulation Jing Shi attenuate doxorubicin-induced cardiac damage	26
Acetylshikonin induces necroptosis via the RIPK1/RIPK3-dependent pathway in lung cancer	25
The mechanism of simultaneous intake of Jujuboside A and B in the regulation of sleep at the hypothalamic level	25
A novel and robust pyroptosis-related prognostic signature predicts prognosis and response to immunotherapy in esophageal squamous cell carcinoma	25
G6PD is a prognostic biomarker correlated with immune infiltrates in lung adenocarcinoma and pulmonary arterial hypertension	25
GSG2 promotes thyroid cancer via stabilizing AURKB and activating AKT pathway	25
Identification and validation of diagnostic signature genes in non-obstructive azoospermia by machine learning	25

Targeting PERK-ATF4-P21 axis enhances the sensitivity of osteosarcoma HOS cells to Mppα-PDT	24
Analysis of multiple factors influencing the survival of patients with advanced gastric cancer	24
Retraction: CircNF1-419 improves the gut microbiome structure and function in AD-like mice	24
A novel predictive model based on inflammatory response-related genes for predicting endometrial cancer prognosis and its experimental validation	24
Identification of senescence-related lncRNA prognostic index correlating with prognosis and radiosensitivity in prostate cancer patients	24
Retraction: Coagulation factor 2 thrombin receptor promotes malignancy in glioma under SOX2 regulation	24
RGC32 promotes the progression of ccRCC by activating the NF-κB/SHP2/EGFR signaling pathway	24
Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease	23
Retraction of: PHTF2 regulates lipids metabolism in gastric cancer	23
Brown adipose tissue enhances exercise performance and healthful longevity	23
Hepatoprotective effect of syringin combined with costunolide against LPS-induced acute liver injury in L-02 cells via Rac1/AKT/NF-κB signaling pathway	23
Micheliolide prevents estrogen deficiency-induced bone loss via inhibiting osteoclast bone resorption	23
Crosstalk of cuproptosis-related prognostic signature and competing endogenous RNAs regulation in hepatocellular carcinoma	23
Machine learning-based B cell-related diagnostic biomarker signature and molecular subtypes characteristic of ulcerative colitis	23
Comprehensive clinical application analysis of artificial intelligence-enabled electrocardiograms for screening multiple valvular heart diseases	23
Predictive value of FCGBP expression for treatment response and survival in rectal cancer patients undergoing chemoradiotherapy	23
Deep learning and generative artificial intelligence in aging research and healthy longevity medicine	22
Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity	22
Fetal programming: in utero exposure to acrylamide leads to intergenerational disrupted ovarian function and accelerated ovarian aging	22
Berberine mitigates intracerebral hemorrhage-induced neuroinflammation in a gut microbiota-dependent manner in mice	22
Beyond amyloid: altered gene function in neurodegenerative diseases	22
DNA methylation-driven gene FAM3D promotes colorectal cancer growth via the ATF4-SESN2-mTORC1 pathway	22
New insights into ginsenoside Rg1 regulating the niche to inhibit age-induced germline stem cells depletion through targeting ECR/BMP signaling pathway in Drosophila	21
DOK7, a target of miR-299-5p, suppresses the progression of bladder cancer	21
A new model and precious tool to study molecular mechanisms of macrophage aging	21
Manganese and IL-12 treatment alters the ovarian tumor microenvironment	21
Correction for: CXCR4 knockdown enhances sensitivity of paclitaxel via the PI3K/Akt/mTOR pathway in ovarian carcinoma	21
Enhanced serum levels of tumor necrosis factor-α, interleukin-1β, and -6 in sarcopenia: alleviation through exercise and nutrition intervention	21
NDUFB11 and NDUFS3 play a role in atherosclerosis and chronic stress	21
Molecular characterization of ferroptosis in soft tissue sarcoma constructs a prognostic and immunotherapeutic signature through experimental and bioinformatics analyses	21
Systematic analysis of glutamine metabolism family genes and exploration of the biological role of GPT in colorectal cancer	21
Bridging cognition and action: executive functioning mediates the relationship between white matter fiber density and complex motor abilities in older adults	21
Single-cell landscape and spatial transcriptomic analysis reveals macrophage infiltration and glycolytic metabolism in kidney renal clear cell carcinoma	20
A lactate metabolism-related gene signature to diagnose osteoarthritis based on machine learning combined with experimental validation	20
Causal role of blood metabolites in HER-positive and HER-negative breast cancer: a Mendelian randomization (MR) study	20
The protective effects of Arctiin in asthma by attenuating airway inflammation and inhibiting p38/NF-κB signaling	20
Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function	20
Rutin promotes osteogenic differentiation of mesenchymal stem cells (MSCs) by increasing ECM deposition and inhibiting p53 expression	20
Impact of sarcopenic obesity on functional outcomes	20
Development of anoikis-related long non-coding RNA signature associated with prognosis and immune landscape in cutaneous melanoma patients	20
Identification and validation of a novel signature based on macrophage marker genes for predicting prognosis and drug response in kidney renal clear cell carcinoma by integrated analysis of single cel	20
Netrin-1 mitigates acute lung injury by preventing the activation of the Toll-like receptor 4/nuclear factor-κB (TLR4/NF-κB) signaling	20
Discovery and identification of the prognostic significance and potential mechanism of FMO2 in breast cancer	20
Identification of immune subtypes to guide immunotherapy and targeted therapy in clear cell renal cell carcinoma	19
Peto’s paradox’s relevance is off the scale	19
Development of tryptophan metabolism patterns to predict prognosis and immunotherapeutic responses in hepatocellular carcinoma	19
Contribution of membrane raft redox signalling to visfatin-induced inflammasome activation and podocyte injury	19
Inhibition of UFM1 expression suppresses cancer progression and is linked to the dismal prognosis and immune infiltration in oral squamous cell carcinoma	19
Cut-off values for the muscle mass indices determined using DXA in healthy Polish adults – a comparison to EWGSOP2 recommendation	19
Reproductive aging, preimplantation genetic testing for aneuploidy, and the diameter of blastocysts: does size matter?	19
Retraction of: Long noncoding RNA NR2F1-AS1 promotes the malignancy of non-small cell lung cancer via sponging microRNA-493-5p and thereby increasing ITGB1 expression	19
Investigation of Tongxie-Yaofang formula in treating ulcerative colitis based on network pharmacology via regulating MAPK/AKT signaling pathway	19
Caloric restriction mitigates age-associated senescence characteristics in subcutaneous adipose tissue-derived stem cells	19
MIAT promotes myofibroblastic activities and transformation in oral submucous fibrosis through sponging the miR-342-3p/SOX6 axis	19
Multidimensional data analysis revealed thyroiditis-associated TCF19 SNP rs2073724 as a highly ranked protective variant in thyroid cancer	19
Machine learning-based construction of immunogenic cell death-related score for improving prognosis and response to immunotherapy in melanoma	19
FABP6 serves as a new therapeutic target in esophageal tumor	19
The role of molecular subtypes and immune infiltration characteristics based on disulfidptosis-associated genes in lung adenocarcinoma	19
Selective targeting of cancer and senescence via shared metabolic shifts extends lifespan of old mice	18
Comprehensive multi-omics analysis reveals a combination of lncRNAs that synergistically regulate glycolysis and immunotherapeutic effects in renal clear cell carcinoma	18
Multi omics analysis of mitophagy subtypes and integration of machine learning for predicting immunotherapy responses in head and neck squamous cell carcinoma	18
Electroacupuncture alleviates the symptom of depression in mice by regulating the cGAS-STING-NLRP3 signaling	18
Spermidine supplementation and protein restriction protect from organismal and brain aging independently	18
FKBP11 improves the malignant property of osteosarcoma cells and acts as a prognostic factor of osteosarcoma	18
HNRNPA2B1 is a potential biomarker of breast cancer related to prognosis and immune infiltration	18
The prognostic significance and immune correlation of SLC10A3 in low-grade gliomas revealed by bioinformatic analysis and multiple immunohistochemistry	18
Galectin-3 promotes brain injury by modulating the phenotype of microglia via binding TLR-4 after intracerebral hemorrhage	18
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF	18
Association between the sarcopenia index and the risk of stroke in elderly patients with hypertension: a cohort study	18
Plasma exosome proteomics reveals the pathogenesis mechanism of post-stroke cognitive impairment	18
Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features, ATP production, proliferation, and cell migration	18
Palmitic acid inhibits vascular smooth muscle cell switch to synthetic phenotype via upregulation of miR-22 expression	18
Identification and validation of the biomarkers related to ferroptosis in calcium oxalate nephrolithiasis	18
Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV	18
LINC00629, a KLF10-responsive lncRNA, promotes the anticancer effects of apigenin by decreasing Mcl1 stability in oral squamous cell carcinoma	18
Identification of disulfidptosis-associated genes and characterization of immune cell infiltration in thyroid carcinoma	18
Werner syndrome RECQ helicase participates in and directs maintenance of the protein complexes of constitutive heterochromatin in proliferating human cells	17
Gypenoside IX restores Akt/GSK-3β pathway and alleviates Alzheimer’s disease-like neuropathology and cognitive deficits	17
Remote cognitive assessment to early detection of cognitive decline	17
Galectin-1-mediated high NCAPG expression correlates with poor prognosis in gastric cancer	17

The clinicopathologic and molecular features, and treatment outcome of fumarate hydratase-deficient renal cell carcinoma: a retrospective comparison with type 2 papillary renal cell carcinoma	17
Mesenchymal stem cell-specific Sirt1 overexpression prevents sarcopenia induced by 1,25-dihydroxyvitamin D deficiency	17
Senescence and extracellular vesicles: novel partners in vascular amyloidosis	17
Topical ABT-263 treatment reduces aged skin senescence and improves subsequent wound healing	17
Expression of αA-crystallin (CRYAA) in vivo and in vitro models of age-related cataract and the effect of its silencing on HLEB3 cells	17
Integrative analysis based on the cell cycle-related genes identifies TPX2 as a novel prognostic biomarker associated with tumor immunity in breast cancer	17
HCMMD: systematic evaluation of metabolites in body fluids as liquid biopsy biomarker for human cancers	17
Learning by motor imagery in older adults	17
AAT resistance-related AC007405.2 and AL354989.1 as novel diagnostic and prognostic markers in prostate cancer	17
ANGPTL4, a direct target of hsa-miR-133a-3p, accelerates lung adenocarcinoma lipid metabolism, proliferation and invasion	17
Mitochondrial dysfunction, iron accumulation, lipid peroxidation, and inflammasome activation in cellular models derived from patients with multiple sclerosis	17
A prognostic signature established based on genes related to tumor microenvironment for patients with hepatocellular carcinoma	17
Prognostic value and immune landscapes of anoikis-associated lncRNAs in lung adenocarcinoma	17
Identification and validation of eight estrogen-related genes for predicting prognosis of papillary thyroid cancer	17
Impact of Factor Xa inhibitors on cardiovascular events in older patients with nonvalvular atrial fibrillation	16
LINC01296 promotes proliferation of cutaneous malignant melanoma by regulating miR-324-3p/MAPK1 axis	16
SENP3 affects the expression of PYCR1 to promote bladder cancer proliferation and EMT transformation by deSUMOylation of STAT3	16
3D-printed porous zinc scaffold combined with bioactive serum exosomes promotes bone defect repair in rabbit radius	16
	16
miR-506-3p induces autophagy of renal tubular epithelial cells in sepsis through targeting PI3K pathway	16
AK7-deficiency reversal inhibits ccRCC progression and boosts anti-PD1 immunotherapy sensitivity	16
A novel cuproptosis-related lncRNAs signature predicts prognosis in bladder cancer	16
Identification of key lncRNAs in age-related macular degeneration through integrated bioinformatics and experimental validation	16
ERAP2 as a potential biomarker for predicting gemcitabine response in patients with pancreatic cancer	16
UCHL1-PKM2 axis dysregulation is associated with promoted proliferation and invasiveness of urothelial bladder cancer cells	16
Prognostic model of kidney renal clear cell carcinoma using aging-related long noncoding RNA signatures identifies THBS1-IT1 as a potential prognostic biomarker for multiple cancers	16
TBC1D1 represses glioma progression by altering the integrity of the cytoskeleton	16
Humoral immunoresponse elicited against an adenoviral-based SARS-CoV-2 coronavirus vaccine in elderly patients	16
Correction for: Posttranscriptional regulation of AKT by circular RNA angiomotin-like 1 mediates chemoresistance against paclitaxel in breast cancer cells	16
The prognosis, chemotherapy and immunotherapy efficacy of the SUMOylation pathway signature and the role of UBA2 in lung adenocarcinoma	16
Mining key circadian biomarkers for major depressive disorder by integrating bioinformatics and machine learning	16
Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 involvement	16
AURKB promotes colorectal cancer progression by triggering the phosphorylation of histone H3 at serine 10 to activate CCNE1 expression	15
Therapeutic effects of Huangqi formula (Eefooton) in chronic kidney disease: clinical research and narrative literature review	15
Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?	15
A novel signature based on cancer-associated fibroblast genes to predict prognosis, immune feature, and therapeutic response in breast cancer	15
Ferulic acid in synergizing with retinol alleviates oxidative injury of HaCaT cells during UVB-induced photoaging	15
Noncoding RNAs-mediated overexpression of KIF14 is associated with tumor immune infiltration and unfavorable prognosis in lung adenocarcinoma	15
Cognitive rescue in aging through prior training in rats	15
Denervation induces mitochondrial decline and exacerbates lysosome dysfunction in middle-aged mice	15
CDKN2A was a cuproptosis-related gene in regulating chemotherapy resistance by the MAGE-A family in breast cancer: based on artificial intelligence (AI)-constructed pan-cancer risk model	15
T cell senescence by N-glycan branching	15
Epigenetic age and lung cancer risk in the CLUE II prospective cohort study	15
Yangyinghuoxue decoction exerts a treatment effect on hepatic fibrosis by PI3K/AKT pathway in rat model: based on the network pharmacology and molecular docking	15
Revealing a cancer-associated fibroblast-based risk signature for pancreatic adenocarcinoma through single-cell and bulk RNA-seq analysis	15
Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness	15
DNA methylation-estimated phenotypes, telomere length and risk of ischemic stroke: epigenetic age acceleration of screening and a Mendelian randomization study	15
Associations between klotho and telomere biology in high stress caregivers	15
Foundations of Gerophysics	15
Fisetin ameliorates vascular smooth muscle cell calcification via DUSP1-dependent p38 MAPK inhibition	15
Age-associated changes in the heart: implications for COVID-19 therapies	15
Novel insights into the pathogenesis of thyroid eye disease through ferroptosis-related gene signature and immune infiltration analysis	15
Ubiquitin-like protein FAT10 promotes renal fibrosis by stabilizing USP7 to prolong CHK1-mediated G2/M arrest in renal tubular epithelial cells	15
DDIT3 switches osteogenic potential of BMP9 to lipogenic by attenuating Wnt/β-catenin signaling via up-regulating DKK1 in mesenchymal stem cells	15
The effect of age on melanoma incidence and prognosis	15
Characterization of m6A methylation modifications in gastric cancer	15
Restraint stress of female mice during oocyte development facilitates oocyte postovulatory aging	15
Identifying endoplasmic reticulum stress-related molecular subtypes and prognostic model for predicting the immune landscape and therapy response in pancreatic cancer	15
Mitochondrial proteins as biomarkers of cellular senescence and age-associated diseases	15
A new perspective: deciphering the aberrance and clinical implication of disulfidptosis signatures in clear cell renal cell carcinoma	15
NCAPG as a novel prognostic biomarker in numerous cancers: a meta-analysis and bioinformatics analysis	14
Disease progression in Parkinson’s disease patients with mild cognitive impairment: 5-year longitudinal study from the early Parkinson’s disease longitudinal Singapore (PALS) cohort	14
Exploration of bacterial lipopolysaccharide-related genes signature based on T cells for predicting prognosis in colorectal cancer	14
Comprehensive analysis of cellular senescence and immune microenvironment in papillary thyroid carcinoma	14
Association between Epstein-Barr virus serological reactivation and psychological distress: a cross-sectional study of Japanese community-dwelling older adults	14
CRYAB suppresses ferroptosis and promotes osteogenic differentiation of human bone marrow stem cells via binding and stabilizing FTH1	14
Carriers of Parkinson’s disease-linked SNCA Rep1 variant have greater non-motor decline: a 4 year follow up study	14
Retraction of: Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice	14
Pterostilbene enhances reproductive outcomes and oocyte quality in aged mice without adverse effects	14
Shexiang tongxin dropping pill alleviates myocardial injury induced by coronary microembolization by down-regulating APOC1 to inhibit STAT3 signaling pathway	14
S14G-humanin alleviates acute lung injury by inhibiting the activation of NF-κB	14
Clinical significance and integrative analysis of the cuproptosis-associated genes in head and neck squamous cell carcinoma	14
Viral vector-mediated upregulation of serine racemase expression in medial prefrontal cortex improves learning and synaptic function in middle age rats	14
TMT-based quantitative proteomic analysis revealed that FBLN2 and NPR3 are involved in the early osteogenic differentiation of mesenchymal stem cells (MSCs)	14
Identify miRNA-mRNA regulation pairs to explore potential pathogenesis of lung adenocarcinoma	14
FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet	14
Modified iPOND revealed the role of mutant p53 in promoting helicase function and telomere maintenance	14
Abnormal myocardial enzymes in the prediction of mortality and hypertension in COVID-19 patients: a retrospective study	14
Short telomeres in alveolar type II cells associate with lung fibrosis in post COVID-19 patients with cancer	14
Evaluating the nonlinear effects of sleep duration on biological aging across phenotypic, genomic, and epigenomic data	14
Inhibition of keloid by 32P isotope radiotherapy through suppressing TGF-β/Smad signaling pathway	14
Genetic effect of thyroid function-related diseases on acute respiratory distress syndrome: a Mendelian randomization study	14
Exploring the role of acylated ghrelin and gut microbiome in delineating cognitive health in the elderly	14
Correction for: Comprehensive analysis of prognostic value, relationship to cell cycle, immune infiltration and m6A modification of ZSCAN20 in hepatocellular carcinoma	14
Mechanism of ameliorating cerebral ischemia/reperfusion injury by antioxidant inhibition of autophagy based on network pharmacology and experimental verification	14
The role of miR-6884-5p in epithelial-mesenchymal transition in non-small cell lung cancer	14
Circulating immune cell phenotypes are associated with age, sex, CMV, and smoking status in the Framingham Heart Study offspring participants	14
Correction for: The association between KLF4 as a tumor suppressor and the prognosis of hepatocellular carcinoma after curative resection	14
Role of NF-κB pathway in kidney renal clear cell carcinoma and its potential therapeutic implications	14
Models for age-specific estimation of appendicular skeletal muscle mass using the ultrasound-measured rectus femoris muscle thickness	14
Development and validation of a novel T cell proliferation-related prognostic model for predicting survival and immunotherapy benefits in melanoma	14
Correction for: Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy	13
ALKBH family members as novel biomarkers and prognostic factors in human breast cancer	13
miR-153-3p suppresses the differentiation and proliferation of neural stem cells via targeting GPR55	13
Regulation of endothelial ferroptosis by SESN1 in atherosclerosis and its related mechanism	13