Aging-US

Article	Citations
	278
Vascular function in the aging human brain during muscle exertion	150
Correction: Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial	118
Causal role of immune cells in prostate cancer: a bidirectional Mendelian-randomization analyses	88
LncRNA DANCR suppresses acute myocardial infarction in mice via mediating p-RXRA/TRAF2/NIK/IKK/NF-κB signaling pathway	65
Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma	52
The impact of ALDH7A1 variants in oral cancer development and prognosis	50
PUS1 is a novel biomarker for evaluating malignancy of human renal cell carcinoma	49
Identification of circRNA-miRNA-mRNA networks to explore the molecular mechanism and immune regulation of postoperative neurocognitive disorder	46
Comprehensive analysis of integrin αvβ3/α6β1 in prognosis and immune escape of prostate cancer	45
ZhenQi FuZheng formula inhibits the growth of colorectal tumors by modulating intestinal microflora-mediated immune function	45
Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence	45
An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis	44
Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer	44
In vivo tau staging in Alzheimer’s disease	44
Epigenetic aging signatures and age prediction in human skeletal muscle	43
AR12 increases BAG3 expression which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy	42
Mapping the core senescence phenotype of primary human colon fibroblasts	41
Inhibition of BACE1 attenuates microglia-induced neuroinflammation after intracerebral hemorrhage by suppressing STAT3 activation	41
S100A9, as a potential predictor of prognosis and immunotherapy response for GBM, promotes the malignant progression of GBM cells and migration of M2 macrophages	41
Association between dipeptidyl peptidase-4 inhibitor use and risk of Parkinson’s disease among patients with diabetes mellitus: a retrospective cohort study	40
CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction	40
Organotypic cultures as aging associated disease models	39
Investigating causal associations among gut microbiota, gut microbiota-derived metabolites, and gestational diabetes mellitus: a bidirectional Mendelian randomization study	39
Unraveling the unfolded protein response signature: implications for tumor immune microenvironment heterogeneity and clinical prognosis in stomach cancer	38

BMAL1 modulates senescence programming via AP-1	38
Pan-cancer analysis of disulfidptosis with potential implications in prognosis, immune microenvironment, and drug resistance in human cancer	38
Interleukin-17D promotes lung cancer progression by inducing tumor-associated macrophage infiltration via the p38 MAPK signaling pathway	38
The potential benefit of metformin to reduce delirium risk and mortality: a retrospective cohort study	37
Advanced age is not the decisive factor in chemotherapy of small cell lung cancer: a population-based study	37
THY1 is a prognostic-related biomarker via mediating immune infiltration in lung squamous cell carcinoma (LUSC)	37
Identification and validation of immunogenic cell death-related score in uveal melanoma to improve prediction of prognosis and response to immunotherapy	37
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats	36
Development and validation of a combined cuproptosis and immunogenic cell death prognostic model for diffuse large B-cell lymphoma	36
Potential reversal of biological age in women following an 8-week methylation-supportive diet and lifestyle program: a case series	34
Brief, weekly magnetic muscle therapy improves mobility and lean body mass in older adults: a Southeast Asia community case study	34
Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results	32
Identification and validation of oxeiptosis-associated lncRNAs and prognosis-related signature genes to predict the immune status in uterine corpus endometrial carcinoma	32
Ferulic acid ameliorates the quality of in vitro-aged bovine oocytes by suppressing oxidative stress and apoptosis	32
Multilevel data integration and molecular docking approach to systematically elucidate the underlying pharmacological mechanisms of Er-Zhi-Wan against hepatocellular carcinoma	31
Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma	31
Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC	30
Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies	30
Two lncRNA signatures with cuproptosis as a novel prognostic model and clinicopathological value for endometrioid endometrial adenocarcinoma	30
DNA methylation entropy is a biomarker for aging	30
Beyond amyloid: altered gene function in neurodegenerative diseases	29
On the lifespan of Enchytraeus crypticus - impact of iron (nanomaterial and salt) on aging	29
Identification of VEGFs-related gene signature for predicting microangiogenesis and hepatocellular carcinoma prognosis	29
Serum adenosine deaminase activity and acute cerebral infarction: a retrospective case-control study based on 7913 participants	29
Machine learning-based B cell-related diagnostic biomarker signature and molecular subtypes characteristic of ulcerative colitis	28
A neural network model was constructed by screening the potential biomarkers of aortic dissection based on genes associated with pyroptosis	27
Elderly CD8+ T cells in the focus for immunotherapeutic approaches	27
Age, sex, and mitochondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat model	27
Development of a prognostic model based on anoikis-related genes for predicting clinical prognosis and immunotherapy of hepatocellular carcinoma	27
The rodent aging interventions database (RAID): a data visualization tool for all studies reporting rodent lifespan extension	27
Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity	27
Sofosbuvir induces gene expression for promoting cell proliferation and migration of hepatocellular carcinoma cells	27
Hairy gene homolog increases nasopharyngeal carcinoma cell stemness by upregulating Bmi-1	26
FAM46C-mediated tumor heterogeneity predicts extramedullary metastasis and poorer survival in multiple myeloma	26
A new model and precious tool to study molecular mechanisms of macrophage aging	26
Correction for: Sonic hedgehog signaling promotes angiogenesis of endothelial progenitor cells to improve pressure ulcers healing by PI3K/AKT/eNOS signaling	26
Physical fitness and lifestyles associated with biological aging	26
Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease	26
Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome	26
Growth hormone excess drives liver aging via increased glycation stress	26
Comprehensive clinical application analysis of artificial intelligence-enabled electrocardiograms for screening multiple valvular heart diseases	26
Correction for: circACTA2 mediates Ang II-induced VSMC senescence by modulation of the interaction of ILF3 with CDK4 mRNA	25
New insights into ginsenoside Rg1 regulating the niche to inhibit age-induced germline stem cells depletion through targeting ECR/BMP signaling pathway in Drosophila	25
Development and validation of a novel model for predicting the survival of bladder cancer based on ferroptosis-related genes	25
Prognostic significance and immune characteristics of GPR27 in gastric cancer	25
Retraction of: Extracellular vesicle derived miR-544 downregulates expression of tumor suppressor promyelocytic leukemia zinc finger resulting in increased peritoneal metastasis in gastric cancer	25
Human adipose-derived stem cells preconditioned with a novel herbal formulation Jing Shi attenuate doxorubicin-induced cardiac damage	25
Micheliolide prevents estrogen deficiency-induced bone loss via inhibiting osteoclast bone resorption	25
Associations between serum total cholesterol level and bone mineral density in older adults	24
Integrative analysis of single-cell and bulk RNA sequencing unveils the senescence landscape in ischemic stroke	24

Novel insights into the regulatory role of N6-methyladenosine methylation modified autophagy in sepsis	24
NDUFB11 and NDUFS3 play a role in atherosclerosis and chronic stress	24
Bridging cognition and action: executive functioning mediates the relationship between white matter fiber density and complex motor abilities in older adults	24
RGC32 promotes the progression of ccRCC by activating the NF-κB/SHP2/EGFR signaling pathway	23
HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis	23
Retraction of: PHTF2 regulates lipids metabolism in gastric cancer	23
A novel predictive model based on inflammatory response-related genes for predicting endometrial cancer prognosis and its experimental validation	23
Retraction: Coagulation factor 2 thrombin receptor promotes malignancy in glioma under SOX2 regulation	23
Crosstalk of cuproptosis-related prognostic signature and competing endogenous RNAs regulation in hepatocellular carcinoma	23
Isoaspartate and neurodegeneration	23
Targeting PERK-ATF4-P21 axis enhances the sensitivity of osteosarcoma HOS cells to Mppα-PDT	23
Retraction: CircNF1-419 improves the gut microbiome structure and function in AD-like mice	23
Predictive value of FCGBP expression for treatment response and survival in rectal cancer patients undergoing chemoradiotherapy	23
Hepatoprotective effect of syringin combined with costunolide against LPS-induced acute liver injury in L-02 cells via Rac1/AKT/NF-κB signaling pathway	22
Combination of 7-O-geranylquercetin and microRNA-451 enhances antitumor effect of Adriamycin by reserving P-gp-mediated drug resistance in breast cancer	22
The mechanism of simultaneous intake of Jujuboside A and B in the regulation of sleep at the hypothalamic level	22
Acetylshikonin induces necroptosis via the RIPK1/RIPK3-dependent pathway in lung cancer	22
A novel and robust pyroptosis-related prognostic signature predicts prognosis and response to immunotherapy in esophageal squamous cell carcinoma	22
Fetal programming: in utero exposure to acrylamide leads to intergenerational disrupted ovarian function and accelerated ovarian aging	22
GSG2 promotes thyroid cancer via stabilizing AURKB and activating AKT pathway	22
Enhanced serum levels of tumor necrosis factor-α, interleukin-1β, and -6 in sarcopenia: alleviation through exercise and nutrition intervention	22
G6PD is a prognostic biomarker correlated with immune infiltrates in lung adenocarcinoma and pulmonary arterial hypertension	22
Identification of senescence-related lncRNA prognostic index correlating with prognosis and radiosensitivity in prostate cancer patients	22
Brown adipose tissue enhances exercise performance and healthful longevity	21
Machine learning constructs a T cell-related signature for predicting prognosis and drug sensitivity in ovarian cancer	21
Ros-mediated mitochondrial oxidative stress is involved in the ameliorating effect of ginsenoside GSLS on chlorpyrifos-induced hepatotoxicity in mice	21
Analysis of multiple factors influencing the survival of patients with advanced gastric cancer	21
Berberine mitigates intracerebral hemorrhage-induced neuroinflammation in a gut microbiota-dependent manner in mice	21
DNA methylation-driven gene FAM3D promotes colorectal cancer growth via the ATF4-SESN2-mTORC1 pathway	21
Identification and validation of an anoikis-related genes signature for prognostic implication in papillary thyroid cancer	21
Systematic analysis of glutamine metabolism family genes and exploration of the biological role of GPT in colorectal cancer	20
Correction for: CXCR4 knockdown enhances sensitivity of paclitaxel via the PI3K/Akt/mTOR pathway in ovarian carcinoma	20
Correction for: Menstrual blood-derived stem cells and its mitochondrial treatment improve the ovarian condition of aged mice	20
Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV	20
Identification and validation of diagnostic signature genes in non-obstructive azoospermia by machine learning	20
Molecular characterization of ferroptosis in soft tissue sarcoma constructs a prognostic and immunotherapeutic signature through experimental and bioinformatics analyses	20
Manganese and IL-12 treatment alters the ovarian tumor microenvironment	20
ANGPTL4, a direct target of hsa-miR-133a-3p, accelerates lung adenocarcinoma lipid metabolism, proliferation and invasion	20
The protective effects of Arctiin in asthma by attenuating airway inflammation and inhibiting p38/NF-κB signaling	20
Deep learning and generative artificial intelligence in aging research and healthy longevity medicine	20
Human umbilical cord mesenchymal stem cells promote steroid-induced osteonecrosis of the femoral head repair by improving microvascular endothelial cell function	20
DOK7, a target of miR-299-5p, suppresses the progression of bladder cancer	20
Netrin-1 mitigates acute lung injury by preventing the activation of the Toll-like receptor 4/nuclear factor-κB (TLR4/NF-κB) signaling	20
Development of anoikis-related long non-coding RNA signature associated with prognosis and immune landscape in cutaneous melanoma patients	20
Identification of immune subtypes to guide immunotherapy and targeted therapy in clear cell renal cell carcinoma	19
A lactate metabolism-related gene signature to diagnose osteoarthritis based on machine learning combined with experimental validation	19
Reproductive aging, preimplantation genetic testing for aneuploidy, and the diameter of blastocysts: does size matter?	19
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF	19
Causal role of blood metabolites in HER-positive and HER-negative breast cancer: a Mendelian randomization (MR) study	19
Discovery and identification of the prognostic significance and potential mechanism of FMO2 in breast cancer	19
Development of tryptophan metabolism patterns to predict prognosis and immunotherapeutic responses in hepatocellular carcinoma	19
Multidimensional data analysis revealed thyroiditis-associated TCF19 SNP rs2073724 as a highly ranked protective variant in thyroid cancer	19
Expression of αA-crystallin (CRYAA) in vivo and in vitro models of age-related cataract and the effect of its silencing on HLEB3 cells	19
Single-cell landscape and spatial transcriptomic analysis reveals macrophage infiltration and glycolytic metabolism in kidney renal clear cell carcinoma	19
MIAT promotes myofibroblastic activities and transformation in oral submucous fibrosis through sponging the miR-342-3p/SOX6 axis	19
Machine learning-based construction of immunogenic cell death-related score for improving prognosis and response to immunotherapy in melanoma	19
Peto’s paradox’s relevance is off the scale	19
FKBP11 improves the malignant property of osteosarcoma cells and acts as a prognostic factor of osteosarcoma	19
Cut-off values for the muscle mass indices determined using DXA in healthy Polish adults – a comparison to EWGSOP2 recommendation	19
Impact of sarcopenic obesity on functional outcomes	19
Galectin-3 promotes brain injury by modulating the phenotype of microglia via binding TLR-4 after intracerebral hemorrhage	18
FABP6 serves as a new therapeutic target in esophageal tumor	18
The role of molecular subtypes and immune infiltration characteristics based on disulfidptosis-associated genes in lung adenocarcinoma	18
Association between the sarcopenia index and the risk of stroke in elderly patients with hypertension: a cohort study	18
Rutin promotes osteogenic differentiation of mesenchymal stem cells (MSCs) by increasing ECM deposition and inhibiting p53 expression	18
Identification of disulfidptosis-associated genes and characterization of immune cell infiltration in thyroid carcinoma	18
Contribution of membrane raft redox signalling to visfatin-induced inflammasome activation and podocyte injury	18
Werner syndrome RECQ helicase participates in and directs maintenance of the protein complexes of constitutive heterochromatin in proliferating human cells	18
Mitochondrial dysfunction, iron accumulation, lipid peroxidation, and inflammasome activation in cellular models derived from patients with multiple sclerosis	18
Retraction of: Long noncoding RNA NR2F1-AS1 promotes the malignancy of non-small cell lung cancer via sponging microRNA-493-5p and thereby increasing ITGB1 expression	18
Identification and validation of a novel signature based on macrophage marker genes for predicting prognosis and drug response in kidney renal clear cell carcinoma by integrated analysis of single cel	18
Investigation of Tongxie-Yaofang formula in treating ulcerative colitis based on network pharmacology via regulating MAPK/AKT signaling pathway	18
Inhibition of UFM1 expression suppresses cancer progression and is linked to the dismal prognosis and immune infiltration in oral squamous cell carcinoma	18
Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features, ATP production, proliferation, and cell migration	17
Comprehensive multi-omics analysis reveals a combination of lncRNAs that synergistically regulate glycolysis and immunotherapeutic effects in renal clear cell carcinoma	17
Mesenchymal stem cell-specific Sirt1 overexpression prevents sarcopenia induced by 1,25-dihydroxyvitamin D deficiency	17
Senescence and extracellular vesicles: novel partners in vascular amyloidosis	17
Integrative analysis based on the cell cycle-related genes identifies TPX2 as a novel prognostic biomarker associated with tumor immunity in breast cancer	17
LINC00629, a KLF10-responsive lncRNA, promotes the anticancer effects of apigenin by decreasing Mcl1 stability in oral squamous cell carcinoma	17
Spermidine supplementation and protein restriction protect from organismal and brain aging independently	17

Multi omics analysis of mitophagy subtypes and integration of machine learning for predicting immunotherapy responses in head and neck squamous cell carcinoma	17
Gypenoside IX restores Akt/GSK-3β pathway and alleviates Alzheimer’s disease-like neuropathology and cognitive deficits	17
Topical ABT-263 treatment reduces aged skin senescence and improves subsequent wound healing	17
Remote cognitive assessment to early detection of cognitive decline	17
FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet	17
The prognostic significance and immune correlation of SLC10A3 in low-grade gliomas revealed by bioinformatic analysis and multiple immunohistochemistry	17
Caloric restriction mitigates age-associated senescence characteristics in subcutaneous adipose tissue-derived stem cells	17
Effective natural inhibitors targeting IGF-1R by computational study	17
Plasma exosome proteomics reveals the pathogenesis mechanism of post-stroke cognitive impairment	17
AAT resistance-related AC007405.2 and AL354989.1 as novel diagnostic and prognostic markers in prostate cancer	17
Characterization of m6A methylation modifications in gastric cancer	17
A prognostic signature established based on genes related to tumor microenvironment for patients with hepatocellular carcinoma	17
Palmitic acid inhibits vascular smooth muscle cell switch to synthetic phenotype via upregulation of miR-22 expression	17
Electroacupuncture alleviates the symptom of depression in mice by regulating the cGAS-STING-NLRP3 signaling	17
Identification and validation of the biomarkers related to ferroptosis in calcium oxalate nephrolithiasis	17
HNRNPA2B1 is a potential biomarker of breast cancer related to prognosis and immune infiltration	17
HCMMD: systematic evaluation of metabolites in body fluids as liquid biopsy biomarker for human cancers	16
The clinicopathologic and molecular features, and treatment outcome of fumarate hydratase-deficient renal cell carcinoma: a retrospective comparison with type 2 papillary renal cell carcinoma	16
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The prognosis, chemotherapy and immunotherapy efficacy of the SUMOylation pathway signature and the role of UBA2 in lung adenocarcinoma	16
DDIT3 switches osteogenic potential of BMP9 to lipogenic by attenuating Wnt/β-catenin signaling via up-regulating DKK1 in mesenchymal stem cells	16
Learning by motor imagery in older adults	16
AK7-deficiency reversal inhibits ccRCC progression and boosts anti-PD1 immunotherapy sensitivity	16
Prognostic value and immune landscapes of anoikis-associated lncRNAs in lung adenocarcinoma	16
Impact of Factor Xa inhibitors on cardiovascular events in older patients with nonvalvular atrial fibrillation	16
Galectin-3 induces vascular smooth muscle cells calcification via AMPK/TXNIP pathway	16
The effect of age on melanoma incidence and prognosis	16
The role of miR-6884-5p in epithelial-mesenchymal transition in non-small cell lung cancer	16
Galectin-1-mediated high NCAPG expression correlates with poor prognosis in gastric cancer	16
Yangyinghuoxue decoction exerts a treatment effect on hepatic fibrosis by PI3K/AKT pathway in rat model: based on the network pharmacology and molecular docking	16
TBC1D1 represses glioma progression by altering the integrity of the cytoskeleton	16
Cognitive rescue in aging through prior training in rats	16
Revealing a cancer-associated fibroblast-based risk signature for pancreatic adenocarcinoma through single-cell and bulk RNA-seq analysis	16
Association between Epstein-Barr virus serological reactivation and psychological distress: a cross-sectional study of Japanese community-dwelling older adults	16
Correction for: Posttranscriptional regulation of AKT by circular RNA angiomotin-like 1 mediates chemoresistance against paclitaxel in breast cancer cells	16
Identification and validation of eight estrogen-related genes for predicting prognosis of papillary thyroid cancer	15
Prognostic model of kidney renal clear cell carcinoma using aging-related long noncoding RNA signatures identifies THBS1-IT1 as a potential prognostic biomarker for multiple cancers	15
Identifying endoplasmic reticulum stress-related molecular subtypes and prognostic model for predicting the immune landscape and therapy response in pancreatic cancer	15
Noncoding RNAs-mediated overexpression of KIF14 is associated with tumor immune infiltration and unfavorable prognosis in lung adenocarcinoma	15
Prognostic value and immune characteristics of RUNX gene family in human cancers: a pan-cancer analysis	15
Associations between klotho and telomere biology in high stress caregivers	15
A novel cuproptosis-related lncRNAs signature predicts prognosis in bladder cancer	15
Denervation induces mitochondrial decline and exacerbates lysosome dysfunction in middle-aged mice	15
Age-associated changes in the heart: implications for COVID-19 therapies	15
Profiles of behavioral, social and psychological well-being in old age and their association with mobility-limitation-free survival	15
Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?	15
Novel insights into the pathogenesis of thyroid eye disease through ferroptosis-related gene signature and immune infiltration analysis	15
Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness	15
SENP3 affects the expression of PYCR1 to promote bladder cancer proliferation and EMT transformation by deSUMOylation of STAT3	15
Humoral immunoresponse elicited against an adenoviral-based SARS-CoV-2 coronavirus vaccine in elderly patients	15
Fisetin ameliorates vascular smooth muscle cell calcification via DUSP1-dependent p38 MAPK inhibition	15
Ferulic acid in synergizing with retinol alleviates oxidative injury of HaCaT cells during UVB-induced photoaging	15
ERAP2 as a potential biomarker for predicting gemcitabine response in patients with pancreatic cancer	15
Identification of combined biomarkers for predicting the risk of osteoporosis using machine learning	15
Therapeutic effects of Huangqi formula (Eefooton) in chronic kidney disease: clinical research and narrative literature review	15
A novel signature based on cancer-associated fibroblast genes to predict prognosis, immune feature, and therapeutic response in breast cancer	15
miR-506-3p induces autophagy of renal tubular epithelial cells in sepsis through targeting PI3K pathway	15
CDKN2A was a cuproptosis-related gene in regulating chemotherapy resistance by the MAGE-A family in breast cancer: based on artificial intelligence (AI)-constructed pan-cancer risk model	15
LINC01296 promotes proliferation of cutaneous malignant melanoma by regulating miR-324-3p/MAPK1 axis	15
Ubiquitin-like protein FAT10 promotes renal fibrosis by stabilizing USP7 to prolong CHK1-mediated G2/M arrest in renal tubular epithelial cells	15
DNA methylation-estimated phenotypes, telomere length and risk of ischemic stroke: epigenetic age acceleration of screening and a Mendelian randomization study	15
T cell senescence by N-glycan branching	14
Identification of alanine aminotransferase 1 interaction network via iTRAQ-based proteomics in alternating migration, invasion, proliferation and apoptosis of HepG2 cells	14
Carriers of Parkinson’s disease-linked SNCA Rep1 variant have greater non-motor decline: a 4 year follow up study	14
Correction for: The association between KLF4 as a tumor suppressor and the prognosis of hepatocellular carcinoma after curative resection	14
Molecular characteristics and clinical implications of serine/arginine-rich splicing factors in human cancer	14
Mechanism of ameliorating cerebral ischemia/reperfusion injury by antioxidant inhibition of autophagy based on network pharmacology and experimental verification	14
Correction for: Comprehensive analysis of prognostic value, relationship to cell cycle, immune infiltration and m6A modification of ZSCAN20 in hepatocellular carcinoma	14
Circulating immune cell phenotypes are associated with age, sex, CMV, and smoking status in the Framingham Heart Study offspring participants	14
3D-printed porous zinc scaffold combined with bioactive serum exosomes promotes bone defect repair in rabbit radius	14
Restraint stress of female mice during oocyte development facilitates oocyte postovulatory aging	14
Identification of key lncRNAs in age-related macular degeneration through integrated bioinformatics and experimental validation	14
Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 involvement	14
Identify miRNA-mRNA regulation pairs to explore potential pathogenesis of lung adenocarcinoma	14
Correction for: Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy	14
Viral vector-mediated upregulation of serine racemase expression in medial prefrontal cortex improves learning and synaptic function in middle age rats	14
Exploration of bacterial lipopolysaccharide-related genes signature based on T cells for predicting prognosis in colorectal cancer	14
Comprehensive analysis of cellular senescence and immune microenvironment in papillary thyroid carcinoma	14
A new perspective: deciphering the aberrance and clinical implication of disulfidptosis signatures in clear cell renal cell carcinoma	14
CRYAB suppresses ferroptosis and promotes osteogenic differentiation of human bone marrow stem cells via binding and stabilizing FTH1	14
miR-21 upregulation exacerbates pressure overload-induced cardiac hypertrophy in aged hearts	14
AURKB promotes colorectal cancer progression by triggering the phosphorylation of histone H3 at serine 10 to activate CCNE1 expression	14
Mining key circadian biomarkers for major depressive disorder by integrating bioinformatics and machine learning	14
Hallmarks of cancer and hallmarks of aging	14
Whole-transcriptome sequencing analysis reveal mechanisms of Yiqi Huoxue Yangyin (YHY) decoction in ameliorating D-gal-induced cardiac aging	14
Abnormal myocardial enzymes in the prediction of mortality and hypertension in COVID-19 patients: a retrospective study	14
Epigenetics-based treatment strategies for Alzheimer’s disease	14
TMT-based quantitative proteomic analysis revealed that FBLN2 and NPR3 are involved in the early osteogenic differentiation of mesenchymal stem cells (MSCs)	14
Identification of the ferroptosis-related ceRNA network related to prognosis and tumor immunity for gastric cancer	14
UCHL1-PKM2 axis dysregulation is associated with promoted proliferation and invasiveness of urothelial bladder cancer cells	14
Epigenetic age and lung cancer risk in the CLUE II prospective cohort study	14
Modified iPOND revealed the role of mutant p53 in promoting helicase function and telomere maintenance	14
Mitochondrial proteins as biomarkers of cellular senescence and age-associated diseases	14
Pan-cancer analysis and experimental validation revealed the m6A methyltransferase KIAA1429 as a potential biomarker for diagnosis, prognosis, and immunotherapy	13
Downregulation of Sirt6 by CD38 promotes cell senescence and aging	13