Aging-US

Article	Citations
Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial	173
Metformin protects against myocardial ischemia-reperfusion injury and cell pyroptosis via AMPK/NLRP3 inflammasome pathway	163
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary	154
Bone marrow mesenchymal stem cell-derived exosomes prevent osteoarthritis by regulating synovial macrophage polarization	106
Global incidence and mortality of breast cancer: a trend analysis	106
Puerarin alleviates osteoporosis in the ovariectomy-induced mice by suppressing osteoclastogenesis via inhibition of TRAF6/ROS-dependent MAPK/NF-κB signaling pathways	98
Gut microbiota in patients with Alzheimer’s disease spectrum: a systematic review and meta-analysis	91
Oral administration of Akkermansia muciniphila elevates systemic antiaging and anticancer metabolites	89
Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke	86
Circular RNA RHOT1 promotes progression and inhibits ferroptosis via mir-106a-5p/STAT3 axis in breast cancer	83
Shorter telomere lengths in patients with severe COVID-19 disease	81
Suppressing the KIF20A/NUAK1/Nrf2/GPX4 signaling pathway induces ferroptosis and enhances the sensitivity of colorectal cancer to oxaliplatin	80
High expression of RRM2 as an independent predictive factor of poor prognosis in patients with lung adenocarcinoma	75
Prognoses and genomic analyses of proteasome 26S subunit, ATPase (PSMC) family genes in clinical breast cancer	70
Circular RNA circEPSTI1 accelerates cervical cancer progression via miR-375/409-3P/515-5p-SLC7A11 axis	68
The aging-related risk signature in colorectal cancer	62
Administration of quercetin improves mitochondria quality control and protects the neurons in 6-OHDA-lesioned Parkinson's disease models	61
The efficiency and safety of high-dose vitamin C in patients with COVID-19: a retrospective cohort study	60
Puerarin protects against sepsis-induced myocardial injury through AMPK-mediated ferroptosis signaling	60
Microglia exosomal miRNA-137 attenuates ischemic brain injury through targeting Notch1	60
Coicis semen protects against focal cerebral ischemia-reperfusion injury by inhibiting oxidative stress and promoting angiogenesis via the TGFβ/ALK1/Smad1/5 signaling pathway	59
Age-related DNA methylation changes are sex-specific: a comprehensive assessment	59
Mortality in an Italian nursing home during COVID-19 pandemic: correlation with gender, age, ADL, vitamin D supplementation, and limitations of the diagnostic tests	57
Examining sleep deficiency and disturbance and their risk for incident dementia and all-cause mortality in older adults across 5 years in the United States	57
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3	56

WTAP promotes myocardial ischemia/reperfusion injury by increasing endoplasmic reticulum stress via regulating m6A modification of ATF4 mRNA	56
Identification of key modules and genes associated with breast cancer prognosis using WGCNA and ceRNA network analysis	56
Development of the VISAGE enhanced tool and statistical models for epigenetic age estimation in blood, buccal cells and bones	55
Circular RNA circKIF4A facilitates the malignant progression and suppresses ferroptosis by sponging miR-1231 and upregulating GPX4 in papillary thyroid cancer	54
Tumor-derived exosomal circRNA_102481 contributes to EGFR-TKIs resistance via the miR-30a-5p/ROR1 axis in non-small cell lung cancer	52
Astrocyte-derived exosomes protect hippocampal neurons after traumatic brain injury by suppressing mitochondrial oxidative stress and apoptosis	52
Hsa_circ_0000199 facilitates chemo-tolerance of triple-negative breast cancer by interfering with miR-206/613-led PI3K/Akt/mTOR signaling	51
Factors influencing serum neurofilament light chain levels in normal aging	50
PTP1B inhibitor alleviates deleterious microglial activation and neuronal injury after ischemic stroke by modulating the ER stress-autophagy axis via PERK signaling in microglia	50
Mortality risk of COVID-19 in elderly males with comorbidities: a multi-country study	50
Analysis of METTL3 and METTL14 in hepatocellular carcinoma	49
Exploring diagnostic m6A regulators in endometriosis	48
Isoquercitrin induces apoptosis and autophagy in hepatocellular carcinoma cells via AMPK/mTOR/p70S6K signaling pathway	48
Dexmedetomidine inhibits inflammatory response and autophagy through the circLrp1b/miR-27a-3p/Dram2 pathway in a rat model of traumatic brain injury	48
Novel necroptosis-related gene signature for predicting the prognosis of pancreatic adenocarcinoma	47
Mitophagy and mitochondrial dynamics in type 2 diabetes mellitus treatment	47
MicroRNA-29a-3p delivery via exosomes derived from engineered human mesenchymal stem cells exerts tumour suppressive effects by inhibiting migration and vasculogenic mimicry in glioma	46
Ageing transcriptome meta-analysis reveals similarities and differences between key mammalian tissues	46
Downregulation of miR-155-5p enhances the anti-tumor effect of cetuximab on triple-negative breast cancer cells via inducing cell apoptosis and pyroptosis	45
LncRNA OTUD6B-AS1 promotes paclitaxel resistance in triple negative breast cancer by regulation of miR-26a-5p/MTDH pathway-mediated autophagy and genomic instability	45
Mesenchymal stem cells-derived extracellular vesicles ameliorate Alzheimer’s disease in rat models via the microRNA-29c-3p/BACE1 axis and the Wnt/β-catenin pathway	45
Identification of immune-related LncRNA for predicting prognosis and immunotherapeutic response in bladder cancer	45
Suppression of p16 alleviates the senescence-associated secretory phenotype	44
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway	44
Fusobacterium nucleatum promotes liver metastasis in colorectal cancer by regulating the hepatic immune niche and altering gut microbiota	44
lncRNA DLEU2 acts as a miR-181a sponge to regulate SEPP1 and inhibit skeletal muscle differentiation and regeneration	44
Combination of dasatinib and quercetin improves cognitive abilities in aged male Wistar rats, alleviates inflammation and changes hippocampal synaptic plasticity and histone H3 methylation profile	44
Melatonin attenuates smoking-induced atherosclerosis by activating the Nrf2 pathway via NLRP3 inflammasomes in endothelial cells	43
Cdkn1a transcript variant 2 is a marker of aging and cellular senescence	43
Comprehensive evaluation of the efficacy and safety of LPV/r drugs in the treatment of SARS and MERS to provide potential treatment options for COVID-19	43
Construction and analysis of a joint diagnosis model of random forest and artificial neural network for heart failure	43
Changing epidemiology of calcific aortic valve disease: 30-year trends of incidence, prevalence, and deaths across 204 countries and territories	42
Early diagnosis of lung cancer: which is the optimal choice?	41
Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression	41
LncRNA-SNHG1 promotes macrophage M2-like polarization and contributes to breast cancer growth and metastasis	41
Exosomal miRNA-205 promotes breast cancer chemoresistance and tumorigenesis through E2F1	41
Effect of lncRNA WT1-AS regulating WT1 on oxidative stress injury and apoptosis of neurons in Alzheimer's disease via inhibition of the miR-375/SIX4 axis	40
Fungal co-infection in COVID-19 patients: evidence from a systematic review and meta-analysis	40
Cellular senescence in lymphoid organs and immunosenescence	40
miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the growth and metastasis of osteosarcoma through SOCS3/JAK2/STAT3 axis	40
Resveratrol alleviates bleomycin-induced pulmonary fibrosis via suppressing HIF-1α and NF-κB expression	40
Effects of exercise on cellular and tissue aging	40
HucMSC exosome-delivered 14-3-3ζ alleviates ultraviolet radiation-induced photodamage via SIRT1 pathway modulation	40
Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the	40
Immune infiltration and a ferroptosis-associated gene signature for predicting the prognosis of patients with endometrial cancer	39
Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine	39
Exosomal lncRNA LINC01711 facilitates metastasis of esophageal squamous cell carcinoma via the miR-326/FSCN1 axis	39
Comprehensive analysis of the competing endogenous circRNA-lncRNA-miRNA-mRNA network and identification of a novel potential biomarker for hepatocellular carcinoma	39
A DNA methylation age predictor for zebrafish	39
Sulforaphane promotes C. elegans longevity and healthspan via DAF-16/DAF-2 insulin/IGF-1 signaling	39

Anti-inflammatory effect of resveratrol attenuates the severity of diabetic neuropathy by activating the Nrf2 pathway	39
β cell aging and age-related diabetes	38
Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition	38
Tanshinone IIA attenuates atherosclerosis via inhibiting NLRP3 inflammasome activation	38
Pharmacological blockade of TNFα prevents sarcopenia and prolongs survival in aging mice	38
Emerging roles of nucleotide metabolism in cancer development: progress and prospect	37
Age-dependent remodeling of gut microbiome and host serum metabolome in mice	37
CircRNA hsa_circ_0110102 inhibited macrophage activation and hepatocellular carcinoma progression via miR-580-5p/PPARα/CCL2 pathway	37
Long noncoding RNA NKILA transferred by astrocyte-derived extracellular vesicles protects against neuronal injury by upregulating NLRX1 through binding to mir-195 in traumatic brain injury	37
Ovarian reserve parameters and IVF outcomes in 510 women with poor ovarian response (POR) treated with intraovarian injection of autologous platelet rich plasma (PRP)	37
Exosomes derived from microRNA-512-5p-transfected bone mesenchymal stem cells inhibit glioblastoma progression by targeting JAG1	37
Dysregulation of USP18/FTO/PYCR1 signaling network promotes bladder cancer development and progression	37
Cistanche deserticola polysaccharides alleviate cognitive decline in aging model mice by restoring the gut microbiota-brain axis	36
Upregulation of KIF20A promotes tumor proliferation and invasion in renal clear cell carcinoma and is associated with adverse clinical outcome	36
ARDD 2020: from aging mechanisms to interventions	36
Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1	36
Analysis of gut microbiota and metabolites in patients with rheumatoid arthritis and identification of potential biomarkers	35
Development of prognostic signature based on immune-related genes in muscle-invasive bladder cancer: bioinformatics analysis of TCGA database	35
An immune subtype-related prognostic signature of hepatocellular carcinoma based on single-cell sequencing analysis	35
LncRNA XIST sponges miR-199a-3p to modulate the Sp1/LRRK2 signal pathway to accelerate Parkinson’s disease progression	35
Berberine-induced TFEB deacetylation by SIRT1 promotes autophagy in peritoneal macrophages	35
Trehalose inhibits ferroptosis via NRF2/HO-1 pathway and promotes functional recovery in mice with spinal cord injury	35
CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis	35
rTMS modulates precuneus-hippocampal subregion circuit in patients with subjective cognitive decline	35
Metformin inhibits hepatocellular carcinoma development by inducing apoptosis and pyroptosis through regulating FOXO3	35
Alterations in fecal short chain fatty acids (SCFAs) and branched short-chain fatty acids (BCFAs) in men with benign prostatic hyperplasia (BPH) and metabolic syndrome (MetS)	34
Mental awareness improved mild cognitive impairment and modulated gut microbiome	34
SEDT2/METTL14-mediated m6A methylation awakening contributes to hypoxia-induced pulmonary arterial hypertension in mice	34
Sirt1 improves heart failure through modulating the NF-κB p65/microRNA-155/BNDF signaling cascade	34
LNK promotes granulosa cell apoptosis in PCOS via negatively regulating insulin-stimulated AKT-FOXO3 pathway	34
Global, regional, and national burden of blindness and vision loss due to common eye diseases along with its attributable risk factors from 1990 to 2019: a systematic analysis from the global burden o	34
Indoxyl sulfate caused behavioral abnormality and neurodegeneration in mice with unilateral nephrectomy	34
Formulated Chinese medicine Shaoyao Gancao Tang reduces NLRP1 and NLRP3 in Alzheimer’s disease cell and mouse models for neuroprotection and cognitive improvement	34
Identification and validation of an immune-related gene signature predictive of overall survival in colon cancer	34
Alzheimer’s disease as a chronic maladaptive polyamine stress response	34
Clinical and prognostic pan-cancer analysis of m6A RNA methylation regulators in four types of endocrine system tumors	33
LncRNA PVT1 accelerates malignant phenotypes of bladder cancer cells by modulating miR-194-5p/BCLAF1 axis as a ceRNA	33
Cardiac senescence is alleviated by the natural flavone acacetin via enhancing mitophagy	33
miR-424-5p shuttled by bone marrow stem cells-derived exosomes attenuates osteogenesis via regulating WIF1-mediated Wnt/β-catenin axis	33
The burden of liver cirrhosis and underlying etiologies: results from the global burden of disease study 2017	33
Cerebellar-limbic neurocircuit is the novel biosignature of physio-cognitive decline syndrome	33
DNAmFitAge: biological age indicator incorporating physical fitness	33
Network pharmacology for systematic understanding of Schisandrin B reduces the epithelial cells injury of colitis through regulating pyroptosis by AMPK/Nrf2/NLRP3 inflammasome	33
Neuroprotective effects and mechanisms of action of nicotinamide mononucleotide (NMN) in a photoreceptor degenerative model of retinal detachment	33
Identification of the function and mechanism of m6A reader IGF2BP2 in Alzheimer’s disease	32
Chemical composition and pharmacological mechanism of ephedra-glycyrrhiza drug pair against coronavirus disease 2019 (COVID-19)	32
lncRNA ANRIL aggravates the chemoresistance of pancreatic cancer cells to gemcitabine by targeting inhibition of miR-181a and targeting HMGB1-induced autophagy	32
A new mechanism of POCD caused by sevoflurane in mice: cognitive impairment induced by cross-dysfunction of iron and glucose metabolism	32
lncRNA SNHG4 modulates colorectal cancer cell cycle and cell proliferation through regulating miR-590-3p/CDK1 axis	32
Nicotine exacerbates atherosclerosis through a macrophage-mediated endothelial injury pathway	32
Hepcidin-induced reduction in iron content and PGC-1β expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis	32
RNA N6-methyladenosine demethylase FTO promotes osteoporosis through demethylating Runx2 mRNA and inhibiting osteogenic differentiation	32
miRNA-122-5p stimulates the proliferation and DNA synthesis and inhibits the early apoptosis of human spermatogonial stem cells by targeting CBL and competing with lncRNA CASC7	32
Cancer-associated fibroblasts secreted miR-103a-3p suppresses apoptosis and promotes cisplatin resistance in non-small cell lung cancer	31
lncRNA C2dat2 facilitates autophagy and apoptosis via the miR-30d-5p/DDIT4/mTOR axis in cerebral ischemia-reperfusion injury	31
miR-let-7c-5p and miR-149-5p inhibit proinflammatory cytokine production in osteoarthritis and rheumatoid arthritis synovial fibroblasts	31
GPR30-mediated HMGB1 upregulation in CAFs induces autophagy and tamoxifen resistance in ERα-positive breast cancer cells	31
TRIM3 attenuates apoptosis in Parkinson's disease via activating PI3K/AKT signal pathway	31
Hypoxia induces chemoresistance of esophageal cancer cells to cisplatin through regulating the lncRNA-EMS/miR-758-3p/WTAP axis	31
The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence	31
A combined hypoxia and immune gene signature for predicting survival and risk stratification in triple-negative breast cancer	31
Chemically induced reprogramming to reverse cellular aging	31
Inhibition of Exo-miR-19a-3p derived from cardiomyocytes promotes angiogenesis and improves heart function in mice with myocardial infarction via targeting HIF-1α	31
Global, regional, and national burdens of leukemia from 1990 to 2017: a systematic analysis of the global burden of disease 2017 study	31
The construction and analysis of a ferroptosis-related gene prognostic signature for pancreatic cancer	31
Profilin 2 promotes growth, metastasis, and angiogenesis of small cell lung cancer through cancer-derived exosomes	31
ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration	31
Matrix stiffness promotes glioma cell stemness by activating BCL9L/Wnt/β-catenin signaling	31
Screening of Alzheimer’s disease by facial complexion using artificial intelligence	31
S100A gene family: immune-related prognostic biomarkers and therapeutic targets for low-grade glioma	31
Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis	30
ALKBH5-mediated m6A demethylation of FOXM1 mRNA promotes progression of uveal melanoma	30
Epigenetic age prediction in semen – marker selection and model development	30
Sex and age-related differences in cerebral blood flow investigated using pseudo-continuous arterial spin labeling magnetic resonance imaging	30
PGC-1α alleviates mitochondrial dysfunction via TFEB-mediated autophagy in cisplatin-induced acute kidney injury	30
Comprehensive analysis of ferritin subunits expression and positive correlations with tumor-associated macrophages and T regulatory cells infiltration in most solid tumors	30
DNA methylation-based lung adenocarcinoma subtypes can predict prognosis, recurrence, and immunotherapeutic implications	30
Circular RNA circSEMA5A promotes bladder cancer progression by upregulating ENO1 and SEMA5A expression	29
A glycolysis-related gene expression signature in predicting recurrence of breast cancer	29
Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression	29

Neutrophil extracellular traps, released from neutrophil, promote microglia inflammation and contribute to poor outcome in subarachnoid hemorrhage	29
Facility-based and home-based multidomain interventions including cognitive training, exercise, diet, vascular risk management, and motivation for older adults: a randomized controlled feasibility tri	29
Carbon nanotubes (CNT)-loaded ginsenosides Rb3 suppresses the PD-1/PD-L1 pathway in triple-negative breast cancer	29
circACTA2 mediates Ang II-induced VSMC senescence by modulation of the interaction of ILF3 with CDK4 mRNA	29
Inhibition of long non-coding RNA HOXA11-AS against neuroinflammation in Parkinson's disease model via targeting miR-124-3p mediated FSTL1/NF-κB axis	29
Low expression of NLRP1 is associated with a poor prognosis and immune infiltration in lung adenocarcinoma patients	29
DNA methylation GrimAge version 2	29
Up-regulation of circRNA-0003528 promotes mycobacterium tuberculosis associated macrophage polarization via down-regulating miR-224-5p, miR-324-5p and miR-488-5p and up-regulating CTLA4	29
The long noncoding RNA LINC01140/miR-140-5p/FGF9 axis modulates bladder cancer cell aggressiveness and macrophage M2 polarization	29
miR-21 regulates ischemic neuronal injury via the p53/Bcl-2/Bax signaling pathway	29
GPR43 regulation of mitochondrial damage to alleviate inflammatory reaction in sepsis	28
Chronic metformin treatment decreases cardiac injury during ischemia-reperfusion by attenuating endoplasmic reticulum stress with improved mitochondrial function	28
CircRNA has_circ_0069313 induced OSCC immunity escape by miR-325-3p-Foxp3 axes in both OSCC cells and Treg cells	28
Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer	28
Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer by targeting PI3K/AKT/mTOR signaling	28
LncRNA LINC01305 promotes cervical cancer progression through KHSRP and exosome-mediated transfer	28
Senescence-associated hyper-activation to inflammatory stimuli in vitro	28
A comprehensive review of pancreatic cancer and its therapeutic challenges	28
Overexpression of hsa_circ_0002874 promotes resistance of non-small cell lung cancer to paclitaxel by modulating miR-1273f/MDM2/p53 pathway	28
Ischemic-hypoxic preconditioning enhances the mitochondrial function recovery of transplanted olfactory mucosa mesenchymal stem cells via miR-181a signaling in ischemic stroke	28
Tumor-associated macrophage polarization promotes the progression of esophageal carcinoma	28
Differentially expressed immune response genes in COVID-19 patients based on disease severity	28
LncRNA HAND2-AS1 suppressed the growth of triple negative breast cancer via reducing secretion of MSCs derived exosomal miR-106a-5p	28
CircRNA hsa_circ_0006215 promotes osteogenic differentiation of BMSCs and enhances osteogenesis–angiogenesis coupling by competitively binding to miR-942-5p and regulating RUNX2 and VEGF	27
Immunometabolism at the cornerstone of inflammaging, immunosenescence, and autoimmunity in COVID-19	27
CD36 upregulates DEK transcription and promotes cell migration and invasion via GSK-3β/β-catenin-mediated epithelial-to-mesenchymal transition in gastric cancer	27
Prognostic value of fatty acid metabolism-related genes in patients with hepatocellular carcinoma	27
MiR-16-5p suppresses myofibroblast activation in systemic sclerosis by inhibiting NOTCH signaling	27
Zinc oxide nanoparticles (ZnO NPs) combined with cisplatin and gemcitabine inhibits tumor activity of NSCLC cells	27
LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis	27
LncRNA MAGI2-AS3 inhibits bladder cancer progression by targeting the miR-31-5p/TNS1 axis	27
Coagulopathy in patients with COVID-19: a systematic review and meta-analysis	27
Radiation-induced skin injury: pathogenesis, treatment, and management	27
Preclinical systematic review of ginsenoside Rg1 for cognitive impairment in Alzheimer’s disease	27
The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy	27
miR-545 promotes colorectal cancer by inhibiting transferring in the non-normal ferroptosis signaling	27
In search of preventative strategies: novel high-CBD <i>cannabis sativa</i> extracts modulate ACE2 expression in COVID-19 gateway tissues	27
Cholesterol metabolism in aging simultaneously altered in liver and nervous system	26
Prognostic and clinicopathological significance of systemic immune-inflammation index in pancreatic cancer: a meta-analysis of 2,365 patients	26
Multiwalled carbon nanotubes co-delivering sorafenib and epidermal growth factor receptor siRNA enhanced tumor-suppressing effect on liver cancer	26
NF-κB inducible miR-30b-5p aggravates joint pain and loss of articular cartilage via targeting SIRT1-FoxO3a-mediated NLRP3 inflammasome	26
Circ_0005198 enhances temozolomide resistance of glioma cells through miR-198/TRIM14 axis	26
The lncRNA H19/miR-541-3p/Wnt/β-catenin axis plays a vital role in melatonin-mediated osteogenic differentiation of bone marrow mesenchymal stem cells	26
High phosphate induces skeletal muscle atrophy and suppresses myogenic differentiation by increasing oxidative stress and activating Nrf2 signaling	26
PRMT5 regulates colorectal cancer cell growth and EMT via EGFR/Akt/GSK3β signaling cascades	26
Integrated analysis of tumor-associated macrophage infiltration and prognosis in ovarian cancer	26
Evaluation of droplet digital PCR for quantification of SARS-CoV-2 Virus in discharged COVID-19 patients	26
Circular RNA hsa_circ_0072309 promotes tumorigenesis and invasion by regulating the miR-607/FTO axis in non-small cell lung carcinoma	26
Hypoxia-induced microRNA-155 overexpression in extracellular vesicles promotes renal cell carcinoma progression by targeting FOXO3	26
Age- and gender-specific characteristics of the resting-state brain activity: a magnetoencephalography study	26
LncRNA CYTOR affects the proliferation, cell cycle and apoptosis of hepatocellular carcinoma cells by regulating the miR-125b-5p/KIAA1522 axis	26
Dietary inflammatory potential and risk of sarcopenia: data from national health and nutrition examination surveys	26
Potential role of cannabidiol in Parkinson’s disease by targeting the WNT/β-catenin pathway, oxidative stress and inflammation	26
Integrated analysis of m6A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension	26
miR-224 aggravates cancer-associated fibroblast-induced progression of non-small cell lung cancer by modulating a positive loop of the SIRT3/AMPK/mTOR/HIF-1α axis	26
SNRPB-mediated RNA splicing drives tumor cell proliferation and stemness in hepatocellular carcinoma	25
Integrative radiogenomics analysis for predicting molecular features and survival in clear cell renal cell carcinoma	25
Melatonin protects against focal cerebral ischemia-reperfusion injury in diabetic mice by ameliorating mitochondrial impairments: involvement of the Akt-SIRT3-SOD2 signaling pathway	25
Fighting the storm: could novel anti-TNFα and anti-IL-6 C. sativa cultivars tame cytokine storm in COVID-19?	25
lncRNA MEG3 aggravated neuropathic pain and astrocyte overaction through mediating miR-130a-5p/CXCL12/CXCR4 axis	25
Melatonin inhibits proliferation, migration, and invasion by inducing ROS-mediated apoptosis via suppression of the PI3K/Akt/mTOR signaling pathway in gallbladder cancer cells	25
Matrix stiffness regulates myocardial differentiation of human umbilical cord mesenchymal stem cells	25
A innovative prognostic symbol based on neutrophil extracellular traps (NETs)-related lncRNA signature in non-small-cell lung cancer	25
Fecal microbiota transplantation can improve cognition in patients with cognitive decline and Clostridioides difficile infection	25
Single-cell transcriptome analysis demonstrates inter-patient and intra-tumor heterogeneity in primary and metastatic lung adenocarcinoma	25
Hypoxia induces pulmonary artery smooth muscle dysfunction through mitochondrial fragmentation-mediated endoplasmic reticulum stress	25
LINC00968 can inhibit the progression of lung adenocarcinoma through the miR-21-5p/SMAD7 signal axis	25
Sevoflurane postconditioning reduces myocardial ischemia reperfusion injury-induced necroptosis by up-regulation of OGT-mediated O-GlcNAcylated RIPK3	25
Construction of circRNA-based ceRNA network to reveal the role of circRNAs in the progression and prognosis of metastatic clear cell renal cell carcinoma	25
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages	25
Adalimumab ameliorates memory impairments and neuroinflammation in chronic cerebral hypoperfusion rats	25
Activation of ATF4 triggers trabecular meshwork cell dysfunction and apoptosis in POAG	25
Platelets transport β-amyloid from the peripheral blood into the brain by destroying the blood-brain barrier to accelerate the process of Alzheimer's disease in mouse models	25
Lifetime depression and age-related changes in body composition, cardiovascular function, grip strength and lung function: sex-specific analyses in the UK Biobank	25
piRNA-36741 regulates BMP2-mediated osteoblast differentiation via METTL3 controlled m6A modification	25
Potentiated lung adenocarcinoma (LUAD) cell growth, migration and invasion by lncRNA DARS-AS1 via miR-188-5p/ KLF12 axis	25
A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c	25
Silencing of miR-483-5p alleviates postmenopausal osteoporosis by targeting SATB2 and PI3K/AKT pathway	25
Tumor purity as a prognosis and immunotherapy relevant feature in cervical cancer	25
Expression and molecular profiles of the AlkB family in ovarian serous carcinoma	25
Protective effect of Astragalus membranaceus and Astragaloside IV in sepsis-induced acute kidney injury	24
Betulinic acid induces autophagy-dependent apoptosis via Bmi-1/ROS/AMPK-mTOR-ULK1 axis in human bladder cancer cells	24
The long intergenic noncoding RNA GAS5 reduces cisplatin-resistance in non-small cell lung cancer through the miR-217/LHPP axis	24
Glutamine promotes escape from therapy-induced senescence in tumor cells	24
Matairesinol exerts anti-inflammatory and antioxidant effects in sepsis-mediated brain injury by repressing the MAPK and NF-κB pathways through up-regulating AMPK	24
Hsa_circ_0001869 promotes NSCLC progression via sponging miR-638 and enhancing FOSL2 expression	24
A bioinformatic analysis: the overexpression and clinical significance of FCGBP in ovarian cancer	24
Immunological features beyond CD4/CD8 ratio values in older individuals	24
Hsa_circ_0048179 attenuates free fatty acid-induced steatosis via hsa_circ_0048179/miR-188-3p/GPX4 signaling	24
Oxidative stress mediates age-related hypertrophy of ligamentum flavum by inducing inflammation, fibrosis, and apoptosis through activating Akt and MAPK pathways	24
Fucoxanthin attenuates LPS-induced acute lung injury via inhibition of the TLR4/MyD88 signaling axis	24
Phenotyping of immune and endometrial epithelial cells in endometrial carcinomas revealed by single-cell RNA sequencing	24
The local anesthetic ropivacaine suppresses progression of breast cancer by regulating miR-27b-3p/YAP axis	24
Hyperbaric oxygen therapy alleviates vascular dysfunction and amyloid burden in an Alzheimer’s disease mouse model and in elderly patients	24
Expression and prognostic values of ARID family members in breast cancer	24