(The H4-Index of Aging-US is 58. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis838
Why does COVID-19 disproportionately affect older people?641
Epidemiological, comorbidity factors with severity and prognosis of COVID-19: a systematic review and meta-analysis274
ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy248
Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1239
Lactate dehydrogenase, an independent risk factor of severe COVID-19 patients: a retrospective and observational study142
Metformin protects against myocardial ischemia-reperfusion injury and cell pyroptosis via AMPK/NLRP3 inflammasome pathway142
Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial131
Gut microbiota and metabolite alterations associated with reduced bone mineral density or bone metabolic indexes in postmenopausal osteoporosis125
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary123
lncRNA ZFAS1 promotes lung fibroblast-to-myofibroblast transition and ferroptosis via functioning as a ceRNA through miR-150-5p/SLC38A1 axis119
Serum calcium as a biomarker of clinical severity and prognosis in patients with coronavirus disease 2019109
LncRNA ADAMTS9-AS2 inhibits gastric cancer (GC) development and sensitizes chemoresistant GC cells to cisplatin by regulating miR-223-3p/NLRP3 axis98
Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-1997
Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis88
From causes of aging to death from COVID-1987
Salidroside ameliorates Parkinson's disease by inhibiting NLRP3-dependent pyroptosis87
Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice83
Puerarin alleviates osteoporosis in the ovariectomy-induced mice by suppressing osteoclastogenesis via inhibition of TRAF6/ROS-dependent MAPK/NF-κB signaling pathways83
SirT3 activates AMPK-related mitochondrial biogenesis and ameliorates sepsis-induced myocardial injury82
Bone marrow mesenchymal stem cell-derived exosomes prevent osteoarthritis by regulating synovial macrophage polarization81
Global incidence and mortality of breast cancer: a trend analysis81
De novo design of protein peptides to block association of the SARS-CoV-2 spike protein with human ACE280
Stearoyl-CoA desaturase 1 (SCD1) facilitates the growth and anti-ferroptosis of gastric cancer cells and predicts poor prognosis of gastric cancer79
MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat79
PTX3 modulates the immunoflogosis in tumor microenvironment and is a prognostic factor for patients with clear cell renal cell carcinoma78
Overexpression of METTL3 attenuates high-glucose induced RPE cell pyroptosis by regulating miR-25-3p/PTEN/Akt signaling cascade through DGCR878
Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus77
Effects of intraovarian injection of autologous platelet rich plasma on ovarian reserve and IVF outcome parameters in women with primary ovarian insufficiency76
Oral administration of Akkermansia muciniphila elevates systemic antiaging and anticancer metabolites76
Predictors for imaging progression on chest CT from coronavirus disease 2019 (COVID-19) patients75
Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke74
Shorter telomere lengths in patients with severe COVID-19 disease74
An autophagy-related long non-coding RNA prognostic signature accurately predicts survival outcomes in bladder urothelial carcinoma patients73
PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway71
Immune environment modulation in pneumonia patients caused by coronavirus: SARS-CoV, MERS-CoV and SARS-CoV-270
TREM2 ameliorates neuroinflammatory response and cognitive impairment via PI3K/AKT/FoxO3a signaling pathway in Alzheimer’s disease mice69
Elevated Lactate Dehydrogenase (LDH) level as an independent risk factor for the severity and mortality of COVID-1968
Risk factors for 2019 novel coronavirus disease (COVID-19) patients progressing to critical illness: a systematic review and meta-analysis67
Protective effects of autophagy and NFE2L2 on reactive oxygen species-induced pyroptosis of human nucleus pulposus cells67
Down-regulated ciRS-7/up-regulated miR-7 axis aggravated cartilage degradation and autophagy defection by PI3K/AKT/mTOR activation mediated by IL-17A in osteoarthritis67
A novel immune-related genes prognosis biomarker for melanoma: associated with tumor microenvironment67
Circular RNA RHOT1 promotes progression and inhibits ferroptosis via mir-106a-5p/STAT3 axis in breast cancer67
Dietary type 2 resistant starch improves systemic inflammation and intestinal permeability by modulating microbiota and metabolites in aged mice on high-fat diet66
Heterogeneity in brain distribution of activated microglia and astrocytes in a rat ischemic model of Alzheimer’s disease after 2 years of survival66
The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan66
Exosomal miR-183-5p promotes angiogenesis in colorectal cancer by regulation of FOXO164
A new survival model based on ferroptosis-related genes for prognostic prediction in clear cell renal cell carcinoma64
Prognoses and genomic analyses of proteasome 26S subunit, ATPase (PSMC) family genes in clinical breast cancer64
ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-1964
High expression of RRM2 as an independent predictive factor of poor prognosis in patients with lung adenocarcinoma63
Gut microbiota in patients with Alzheimer’s disease spectrum: a systematic review and meta-analysis63
Suppressing the KIF20A/NUAK1/Nrf2/GPX4 signaling pathway induces ferroptosis and enhances the sensitivity of colorectal cancer to oxaliplatin63
Navitoclax (ABT263) reduces inflammation and promotes chondrogenic phenotype by clearing senescent osteoarthritic chondrocytes in osteoarthritis61
Electroacupuncture ameliorates cerebral ischemia/reperfusion injury by suppressing autophagy via the SIRT1-FOXO1 signaling pathway60
Depletion of exosomal circLDLR in follicle fluid derepresses miR-1294 function and inhibits estradiol production via CYP19A1 in polycystic ovary syndrome60
Genetic regulatory subnetworks and key regulating genes in rat hippocampus perturbed by prenatal malnutrition: implications for major brain disorders59
The efficiency and safety of high-dose vitamin C in patients with COVID-19: a retrospective cohort study58
Age-related shifts in gut microbiota contribute to cognitive decline in aged rats58