OOIR: Observatory of International Research

Papers

(The H4-Index of Aging-US is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Correction for: LncRNA LOC146880 promotes esophageal squamous cell carcinoma progression via miR-328-5p/FSCN1/MAPK axis	259
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats	162
	107
Advanced age is not the decisive factor in chemotherapy of small cell lung cancer: a population-based study	93
DNA methylation entropy is a biomarker for aging	89
Serum adenosine deaminase activity and acute cerebral infarction: a retrospective case-control study based on 7913 participants	87
Vascular function in the aging human brain during muscle exertion	85
Correction: Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial	82
Development and validation of a combined cuproptosis and immunogenic cell death prognostic model for diffuse large B-cell lymphoma	75
S100A9, as a potential predictor of prognosis and immunotherapy response for GBM, promotes the malignant progression of GBM cells and migration of M2 macrophages	75
Causal role of immune cells in prostate cancer: a bidirectional Mendelian-randomization analyses	67
LncRNA DANCR suppresses acute myocardial infarction in mice via mediating p-RXRA/TRAF2/NIK/IKK/NF-κB signaling pathway	65
LncRNA HULC as a potential predictor of prognosis and clinicopathological features in patients with digestive system tumors: a meta-analysis	58
Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results	55
Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence	54
In vivo tau staging in Alzheimer’s disease	47
An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis	46
The potential benefit of metformin to reduce delirium risk and mortality: a retrospective cohort study	44
Identification and validation of immunogenic cell death-related score in uveal melanoma to improve prediction of prognosis and response to immunotherapy	43
AR12 increases BAG3 expression which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy	42
Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer	41
Brief, weekly magnetic muscle therapy improves mobility and lean body mass in older adults: a Southeast Asia community case study	41
Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma	41
Association between dipeptidyl peptidase-4 inhibitor use and risk of Parkinson’s disease among patients with diabetes mellitus: a retrospective cohort study	40
The impact of ALDH7A1 variants in oral cancer development and prognosis	40

PUS1 is a novel biomarker for evaluating malignancy of human renal cell carcinoma	40
miRNA-29 aggravates myocardial infarction via inhibiting the PI3K/mTOR/HIF1α/VEGF pathway	38
Comprehensive analysis of integrin αvβ3/α6β1 in prognosis and immune escape of prostate cancer	37
Identification of circRNA-miRNA-mRNA networks to explore the molecular mechanism and immune regulation of postoperative neurocognitive disorder	37
Ferulic acid ameliorates the quality of in vitro-aged bovine oocytes by suppressing oxidative stress and apoptosis	37
Organotypic cultures as aging associated disease models	36
Identification and validation of oxeiptosis-associated lncRNAs and prognosis-related signature genes to predict the immune status in uterine corpus endometrial carcinoma	36
THY1 is a prognostic-related biomarker via mediating immune infiltration in lung squamous cell carcinoma (LUSC)	36
Two lncRNA signatures with cuproptosis as a novel prognostic model and clinicopathological value for endometrioid endometrial adenocarcinoma	36
Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma	36
Identification and external validation of the hub genes associated with cardiorenal syndrome through time-series and network analyses	35
BMAL1 modulates senescence programming via AP-1	35
Multilevel data integration and molecular docking approach to systematically elucidate the underlying pharmacological mechanisms of Er-Zhi-Wan against hepatocellular carcinoma	35
LINC02362 attenuates hepatocellular carcinoma progression through the miR-516b-5p/SOSC2 axis	35