OOIR: Observatory of International Research

Papers

(The H4-Index of Science Signaling is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Pathogenic putrescine	111
Avoiding conflict with strigolactones	84
Structural analysis of TrkA mutations in patients with congenital insensitivity to pain reveals PLCγ as an analgesic drug target	83
SERINC proteins potentiate antiviral type I IFN production and proinflammatory signaling pathways	78
Aging and age-related disorders, cell by cell	74
ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress	74
Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function	67
Shining a light on rhodopsin signaling	64
Editorial expression of concern	64
Transporting leptin to its targets	62
CISH attenuates homeostatic cytokine signaling to promote lung-specific macrophage programming and function	61
Intrapore lipids hydrophobically gate pannexin-1 channels	60
TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer’s disease	59
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization	59
Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition	52
Signaling dynamics distinguish high- and low-priority neutrophil chemoattractant receptors	51
Nuclear pore decoys fool viruses	48
IFNAR1 and IFNAR2 play distinct roles in initiating type I interferon–induced JAK-STAT signaling and activating STATs	48
TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis	45
VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney	44
Turning a negative into a positive	41
A lifeline for immunotherapy	41
Insulin and T _reg cells	40
A sensitive biosensor of endogenous Gα _i activity enables the accurate characterization of endogenous GPCR agonist responses	39
Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke	38

Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth	38
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment	36
The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells	35
ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis	34
Lipid drops in on Alzheimer’s disease	34
The PdeK-PdeR two-component system promotes unipolar localization of FimX and pilus extension in Xanthomonas oryzae pv. oryzicola	33
Ring around the mitochondria	33
Degradation of HDAC10 by autophagy promotes IRF3-mediated antiviral innate immune responses	33
Metabolic pressure from sensory neurons	33
The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation	33
Targeting AML at the intersection of epigenetics and signaling	33