OOIR: Observatory of International Research

Papers

(The H4-Index of Science Signaling is 38. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Aging and age-related disorders, cell by cell	158
Avoiding conflict with strigolactones	138
Cholinergic signals and antibodies	135
A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer’s disease	110
Nuclear pore decoys fool viruses	98
Pathogenic putrescine	80
The protein RAB5IF promotes BDNF signaling by stimulating the SUMOylation of Gα _i1/3 to reduce depressive-like behaviors in mice	79
A Caenorhabditis elegans spatiotemporal proximity atlas reveals the MAPK p38 as a generator of phenotypic plasticity in vivo	76
ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress	64
TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer’s disease	60
Vagal activation inhibits insulin release through neuronal nitric oxide synthase in obese male mice	58
Brain-derived neurotrophic factor coordinates neuron-intrinsic programs to enhance axonal regeneration in human motor neurons	54
Signaling dynamics distinguish high- and low-priority neutrophil chemoattractant receptors	54
Estrogen-powered kidney protection	53
Human and mouse long noncoding RNAs reengineered for exogenous delivery reduce LPS-induced inflammation in human macrophages and mice	53
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization	49
VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney	48
TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis	48
Turning a negative into a positive	46
APOE ε4 on immunity	46
Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition	46
Ring around the mitochondria	45
Metabolic pressure from sensory neurons	45
Lipid drops in on Alzheimer’s disease	44
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment	43

A sensitive biosensor of endogenous Gα _i activity enables the accurate characterization of endogenous GPCR agonist responses	42
Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke	41
Degradation of HDAC10 by autophagy promotes IRF3-mediated antiviral innate immune responses	41
The APC/C adaptor Cdh1 stabilizes STING to potentiate innate immune activation in renal cell carcinoma	41
The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation	41
Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth	41
IL-33–ST2 signaling promotes stemness in subtypes of myeloid leukemia cells through the Wnt and Notch pathways	41
The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells	41
Gut bugs on drugs	40
cAMPing up cancer immunotherapy	39
The fragile state of opioid withdrawal	39
Modulation by macrocyclic peptides	38
A metabolic regulator for parietal cells	38