OOIR: Observatory of International Research

Papers

(The TQCC of Genetic Testing and Molecular Biomarkers is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Correction to: Association of SNPs in Lipid Metabolism Gene Single Nucleotide Polymorphism with the Risk of Obesity in Children by Elizaveta D. Kulaeva et al. Genet Test Mol Biomarkers 2	23
Correction to: Preanalytic and Analytic Quality System Considerations in Noncoding RNA Biomarker Development for Clinical Diagnostics, by William S. Schleif, et al. Genet Test Mol Biomarker	14
Identification of a Risk Predictive Signature Based on Genes Associated with Tumor Size and Lymph Node Involvement in Breast Cancer	14
−455A Allele May Be a Protective Locus for Aseptic Lower Extremity Superficial Thrombophlebitis	10
Vitamin D Receptor Polymorphisms in a Spanish Cohort of Parkinson's Disease Patients	8
Whole Genome Sequencing Will Reduce the Cost of Diagnostic Odyssey	8
PARP1 Is a Prognostic Marker and Targets NFATc2 to Promote Carcinogenesis in Melanoma	8
Association of the CASP3 rs4647602 Gene Polymorphism with Periodontitis in South Indians of Tamil Ethnicity	8
Evaluation of Soluble Tumor Necrosis Factor-Like Weak Inducer of Apoptosis, Omentin, and Tumor Necrosis Factor-α in Subjects with Periodontitis and Type 2 Diabetes Mellitus	8
Evaluation of Multigene Methylation for Blood-Based Detection of Colorectal Cancer	7
The Evaluation of the Genetic Variation Types of the Uridine Diphosphate Glucuronosyl Transferase 1A1 Gene by Next-Generation Sequencing and Their Effects on Bilirubin Levels in Obese Children	7
Multiple Origin and Tumor Heterogeneity of Prostatic Ductal Adenocarcinoma in the Han Chinese Population	7
Whole-Exome Sequencing Reveals Novel TSPAN12 Variants in Autosomal Dominant Familial Exudative Vitreoretinopathy	7
The 3′UTR Polymorphisms in the NLRP3 Gene Associated with the Risk of COPD and Their Putative Effects on the microRNA Mechanism	7
The Association Between the 5-Hydroxytryptamine Receptor 2A Gene Variants rs6311 and rs6313 and Obstructive Sleep Apnea in the Iranian Kurdish Population	7
CmP Signaling Network Leads to Identification of Prognostic Biomarkers for Triple-Negative Breast Cancer in Caucasian Women	7
C Deletion at the re74650330 Locus of the SLC39A8 Gene (rs74650330) Increases the Risk of Coronary Artery Disease in Individuals with Low-Density Lipoprotein Cholesterol Levels	6
miR-1 Targeted Downregulation of Bcl-2 Increases Chemosensitivity of Lung Cancer Cells	6
A Five-mRNA Expression Signature to Predict Survival in Oral Squamous Cell Carcinoma by Integrated Bioinformatic Analyses	6
A Novel PAX3 Variant in a Chinese Pedigree with Nonsyndromic Cleft Lip With or Without Palate	6
The Role of TMIGD1 as a Tumor Suppressor in Colorectal Cancer	5
A Case–Control Study of the Association Between GSTP1 Gene Polymorphisms (rs1695 and rs1138272) and the Susceptibility to Male Infertility in the Moroccan Population	5
LncRNA PVT1 Regulates miR-1207-5p to Affect Colon Cancer Proliferation and Migration via the Wnt6/β-catenin2 Pathway	5
ICAM1 778G>A (rs1799969), ADD1 1378G>T (rs4961), NPPA 553T>C (rs5065), and NOS3 894G>T (rs1799983) Variants in Infants with Gastroschisis from Western Mexico	5
Identification of IRF1 as a Novel Pyroptosis-Related Prognostic Biomarker of Atopic Dermatitis	5

The Merits and Challenges of Genetic Testing	5
Serum hsa-miR-30e As a Potential Biomarker to Predict the Effect of Neoadjuvant Chemoradiation Therapy in Locally Advanced Rectal Cancer	5
Retraction of: Single Nucleotide Polymorphisms in the PTPN1 Gene Are Associated with Susceptibility to Esophageal Squamous Cell Carcinoma: A Case–Control Study in Inner Mongolia, China;	5
Expanding the Genetic Spectrum of AGXT Gene Variants in Egyptian Patients with Primary Hyperoxaluria Type I	5
Building iHope Genetic Health	5
Association Between Single Nucleotide Polymorphisms of miRNAs and Gastric Cancer: A Scoping Review	5
HFE and Non-HFE Hereditary Hemochromatosis Based on Screening of 854 Individuals: 12 Years of an Iranian Experience	4
miR-132-3p, miR-106b-5p, and miR-19b-3p Are Associated with Brain-Derived Neurotrophic Factor Production and Clinical Activity in Multiple Sclerosis: A Pilot Study	4
Spectrum and Frequencies of Genes for Inherited Hearing Loss in Southwestern Chinese Families	4
MiR-504-3p Has Tumor-Suppressing Activity and Decreases IFITM1 Expression in Non-Small Cell Lung Cancer Cells	4
A C->T Variation in 3′-Untranslated Region Elevates MED12 Protein Level in Breast Cancer That Relates to Better Prognosis	4
Audiologic Measures in an Indigenous Community with A2ML1- and FUT2-Related Otitis Media	4
Asked & Answered: All of Us and What It Means to All of You	4
hsa-miR-1301-3p Promotes the Proliferation and Migration of Nonsmall Cell Lung Cancer Cells and Reduces Radiosensitivity via Targeting Homeodomain-Only Protein Homeobox	4
Value of Serum SRY-Box Transcription Factor 2 Levels Combined with Magnetic Resonance Imaging in the Diagnosis of Endometrial Carcinoma	4
Exploration of the Prognostic Value of m5C Methylation Protein NOP2 and NSUN6 in Colon Cancer	4
Two Novel Frameshift Mutations in the GLI3 Gene Underlie Non-Syndromic Polydactyly in Chinese Families	4
Correlation Between Polymorphisms of the SIRT1 Gene microRNA Target Sites and Diabetic Nephropathy	4
Identification and Functional Investigation of Novel Heterozygous HELQ Mutations in Patients with Sertoli Cell-only Syndrome	4
The PSCA rs2294008 (C/T) Polymorphism Increases the Risk of Gastric and Bladder Cancer: A Meta-Analysis	4
Immune Regulatory Circular RNAs, circRasGEF1B and circHIPK3, are Upregulated in Peripheral Blood Mononuclear Cells of COVID-19 Patients	3
Identification of a Homozygous Mutation of CCDC40 in a Chinese Infertile Man with MMAF and PCD-like Phenotypes	3
Exome Sequencing Reveals Novel TTN Variants in Saudi Patients with Congenital Titinopathies	3
Genomic Landscape of Osteosarcoma of Bone in an Older-Aged Patient Population and Analysis of Possible Etiologies Based on Molecular Signature	3
A Computational Framework to Infer Prostate Cancer-Associated Long Noncoding RNAs and Analyses for Identifying a Competing Endogenous RNA Network	3
Kawasaki Disease: An update on Genetics and Pathophysiology	3
Otitis Media in Children with Down Syndrome Is Associated with Shifts in the Nasopharyngeal and Middle Ear Microbiotas	3
Long Noncoding RNA SLC20A1-1 Induces Nucleus Pulposus Apoptosis by Sponging miR-146a-5p	3
Impact of Macrophage Migration Inhibitory Factor Gene Polymorphisms and Serum Macrophage Migration Inhibitory Factor Levels on Pulmonary and Spinal Tuberculosis Susceptibility: A Pooled Analysis	3
Ferroptosis-Related Genes Are Associated with Radioresistance and Immune Suppression in Head and Neck Cancer	3
Impacts of Overturning Roe v. Wade on Reproductive Health Care	3
Effects of the Methylation Levels for the Breast Cancer Associated Genes BCSG1 and BRCA1 on Cellular Proliferation and Migration	3
Learning from the Past: Discussing Lessons from Reproductive Justice in the Gene-Editing Sphere	3
Retraction of: C/EBPβ Promotion of MMP3-Dependent Tumor Cell Invasion and Association with Metastasis in Colorectal Cancer (10.1089/gtmb.2017.0113)	3
Elevated Expression of ADAM10 Induced by HPV E6 Influences the Prognosis of Cervical Cancer	3
Association Study of 3-untranslated region Haplotype of Human leukocyte antigen-G Gene with Lupus	3
Identifying Diagnostic and Prognostic Differentially Expressed Genes of Gastric Cancer Based on Bioinformatics Analyses of RNA-seq Data	3
Assessment of Multiple Annealing and Looping-Based Amplification Cycle-Based Whole-Genome Amplification for Short Tandem Repeat Genotyping of Low Copy Number-DNA	2
Retraction of: Upregulation of miR-98 Inhibits Apoptosis in Cartilage Cells in Osteoarthritis (doi: 10.1089/gtmb.2016.0011)	2
TP53-Mutated Myelodysplastic Syndrome: A Diagnostic Approach in Different Clinical Settings	2
A Mighty Mouth for Data Sharing	2
Species-Level Profiling of Ixodes pacificus Bacterial Microbiomes Reveals High Variability Across Short Spatial Scales at Different Taxonomic Resolutions	2
Circulating Plasma miR-122 and miR-583 Levels Are Involved in Chronic Hepatitis B Virus Pathogenesis and Serve As Novel Diagnostic Biomarkers	2
Genetic Susceptibility and Disease Activity in Ankylosing Spondylitis: The Role of G Protein-Coupled Receptor 35rs4676410 Polymorphism in a Turkish Population	2
Who Are the Experts?	2
METTL5: A Potential Biomarker for Nonsmall Cell Lung Cancer That Promotes Cancer Cell Proliferation by Interacting with IGF2BP3	2
Association Study of Mitochondrial DNA Haplogroup D and C5178A Polymorphisms with Chronic Kidney Disease	2
YKL-40 Knockdown Decreases Oxidative Stress Damage in Ovarian Granulosa Cells	2
Association Study of Pleural Mesothelioma and Oncogenic Simian Virus 40 in the Crocidolite-Contaminated Area of Dayao County, Yunnan Province, Southwest China	2
The Genetic Association Between TLR-1, -2, -4, and -6 Gene Polymorphisms and Rheumatoid Arthritis Susceptibility in a Chinese Han Population	2

Knockdown of GSG2 Suppresses the Progression of Colorectal Cancer Cells	2
Investigating the Association of MTHFR C677T Gene Polymorphism with Recurrent Spontaneous Abortion Among Azerbaijani Women from Northwest Iran	2
Significant Association of the Catechol-O-Methyltransferase Gene Polymorphism (rs4680) and Opioid Use Disorder in Asian Populations, but not Caucasian Populations: A Meta-analysis	2
High Frequency of Ancestral Haplotype A of Fatty Acid Desaturase Genes in the Yakut Population	2
Improved HUMARA for the Detection of X-Linked Agammaglobulinemia Carriers	2
A Common Variant at 11q23.3 Is Associated with Susceptibility to Atopic Dermatitis in the Han Chinese Population	2
VEGF-2578C/A, -460T/C Polymorphisms and Gastrointestinal Tract Cancer Risk: An Updated Meta-Analysis	2
The Not-So-Melting Pot: Workforce and Patient Research Inequity Caps Genomic Medicine Progress	2
Effects of p450 Polymorphisms on the Clinical Outcomes of Gefitinib Treatment in Patients with Epidermal Growth Factor Receptor Mutation-Positive Non-Small Cell Lung Cancer	2
Relationship Between IL-10 Single Nucleotide Polymorphisms (rs1800871, rs1800872, and rs1800896) and the Severity of COVID-19	2
Analysis of ceRNA Network and Identification of Potential Treatment Target and Biomarkers of Endothelial Cell Injury in Sepsis	2
Development of a High Resolution Melting Curve Analysis for the Detection of Hemoglobin δ-Chain Variants in Thailand and Identification of Hb A2-Walsgrave [codon 52 (GAT>CAT), Asp→His; HBD:c.157G&g	2
Diagnostic Yield and Cost–Benefit When Utilizing Clinical Whole Genome Sequencing	2
Farewell	2
The Application of Artificial Intelligence in the Diagnosis of Cancer and Rare Genetic Diseases	2
Clinicopathological and Prognostic Significance of SMYD3 in Human Cancers: A Systematic Review and Meta-analysis	2
Unselected Women's Experiences of Receiving Genetic Research Results for Hereditary Breast and Ovarian Cancer: A Qualitative Study	2
MTHFR 677C>T and 1298A>C Variants in Mothers of Infants with Down Syndrome from Western Mexico	2
VEXAS Syndrome: A Perspective Focus on Genetics and Hematological Manifestations	2
Investigation of Vascular Endothelial Growth Factor Polymorphisms on Risk, Metastasis, Laterality, and Prognosis of Colorectal Cancer in Turkish Subjects	2
Aberrant Super-Enhancer Landscape in Enzalutamide-Resistant Prostate Cancer Cells	2
Predictive Value of the TP53 p.G245S Mutation Frequency for the Short-Term Recurrence of Hepatocellular Carcinoma as Detected by Pyrophosphate Sequencing	2
Targeted Next-Generation Sequencing Analysis Reveals a Novel Genetic Variant in MYO6 Gene in an Indian Family with Postlingual Nonsyndromic Hearing Loss	2
EPAS1 Promoter Hypermethylation is a Diagnostic and Prognostic Biomarker for Non-Small Cell Lung Cancer	2