OOIR: Observatory of International Research

Papers

(The TQCC of Cold Spring Harbor Perspectives in Biology is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Teaching School Genetics in the 2020s: Why “Naive” Mendelian Genetics Has to Go	187
The Nodes of Ranvier: Mechanisms of Assembly and Maintenance	139
Fisher's Geometric Model as a Tool to Study Speciation	110
Leukocyte Chemotaxis and the Elusive Negative Signals that Make It Work	95
Proteins of the Triadic Excitation–Contraction Coupling Complex in Skeletal Muscle	84
Fibroblast Heterogeneity in Healthy and Wounded Skin	75
Post-Translational Regulation of HMG CoA Reductase	68
The Role of Membrane Lipids in the Formation and Function of Caveolae	67
Angiogenesis in Wound Repair: Too Much of a Good Thing?	66
A History of Cancer Research: Retroviral Insertional Mutagenesis	64
Engineering Proteins Using Statistical Models of Coevolutionary Sequence Information	64
Telomere Dynamics in Human Health and Disease	62
The Role of Microhomology-Mediated End Joining (MMEJ) at Dysfunctional Telomeres	61
Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?	61
A Mechanometabolism Toolbox for Studying Cell Migration	58
Seeing the Membrane from Both Sides Now: Lipid Asymmetry and Its Strange Consequences	57
Regulation of Human Telomerase: from Molecular Interactions to Population Genetics	54
Petabase-Scale Homology Search for Structure Prediction	54
Modeling Normal and Abnormal Circuit Development with Recurrent Neural Networks	52
Diversity of Fibroblasts and Their Roles in Wound Healing	52
Maintaining Telomeres without Telomerase inDrosophila: Novel Mechanisms and Rapid Evolution to Save a Genus	50
Toward Understanding Wound Immunology for High-Fidelity Skin Regeneration	49
Mapping the Retina onto the Brain	48
Blastocrithidia —A Genetic Alien from the Planet Earth	48
Roles and Regulation of the Hippo Signaling Pathway in Mammalian Preimplantation Development	47

Structural Diversity within the Endoplasmic Reticulum—From the Microscale to the Nanoscale	40
Interneuron Diversity: How Form Becomes Function	39
Endoplasmic Reticulum Membrane Contact Sites, Lipid Transport, and Neurodegeneration	39
The Biology of Lipids	38
Lipid Transport from Endoplasmic Reticulum to Autophagic Membranes	38
A TAle of Two Pathways: Tail-Anchored Protein Insertion at the Endoplasmic Reticulum	36
Neotropics as a Cradle for Adaptive Radiations	36
Machine Learning for Protein Science and Engineering	35
Sticking to Membranes: Structure, Function, and Cellular Roles of the Annexin Family of Ca²⁺- and Membrane-Binding Proteins	35
Variability in Neural Circuit Formation	32
Regulators of Oligodendrocyte Differentiation	31
Chromosome Ends in Motion: Telomeres as Hazards and Hubs in Meiosis	31
A History of Cancer Research: Oncogenic Transcription Factors	31
Combining Molecular, Macroevolutionary, and Macroecological Perspectives on the Generation of Diversity	31
Why Do Some Lineages Radiate While Others Do Not? Perspectives for Future Research on Adaptive Radiations	30
Growth Factor and Cytokine Delivery Systems for Wound Healing	30
Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum	30
Glial Cell Development and Function in the Zebrafish Central Nervous System	30
Calcium Signaling and Metabolic Reprogramming in Cancer: Mechanisms and Therapeutic Implications	29
Predictability, an Orrery, and a Speciation Machine: Quest for a Standard Model of Speciation	29
Quantitative Analyses of Coupling in Hybrid Zones	29
Cancer Progression and the Calcium Signaling Toolkit: Expanding Dimensions and Perspectives	29
Niche Theory as an Underutilized Resource for the Study of Adaptive Radiations	28
Genetically Encoded Ca ²⁺ Sensors	28
In the Loop: Unusual DNA Structures at Telomeric Repeats and Their Impact on Telomere Function	27
Calcium Signaling and Pathogenesis of Neurodegenerative Disorders: Potential Therapeutic Opportunities	27
Sex Differences in Mast Cell–Associated Disorders: A Life Span Perspective	26
Developmental Control of Cell Cycle and Signaling	25
Telomeres and Telomerase	25
Calcium Signaling in Migrating Neutrophils	24
Transformation of Plantation Forestry Productivity for Climate Change Mitigation and Adaptation	23
Soft Matter Physics Meets Cell Biology: Transitions of Collective Cell Migration in 3D Environments	23
Mechanobiology of the Hippo–YAP Signaling Network	22
How Neuromembrane Lipids Modulate Membrane Proteins: Insights from G-Protein-Coupled Receptors (GPCRs) and Receptor Tyrosine Kinases (RTKs)	21
Glia at Transition Zones	21
Beyond Fluidity: The Role of Lipid Unsaturation in Membrane Function	21
Ca²⁺ Fluxes across Membrane Contact Sites	21
Hidden Treasures of the Genetic Systems in Yeast Mitochondria	20
Cholesterol, Eukaryotic Lipid Domains, and an Evolutionary Perspective of Transmembrane Signaling	20
The Sensory Ecology of Speciation	19
Development of Prefrontal Circuits and Cognitive Abilities	19
Synthesis and Scope of the Role of Postmating Prezygotic Isolation in Speciation	18
Remyelination in the Central Nervous System	18