OOIR: Observatory of International Research

Papers

(The TQCC of Cold Spring Harbor Perspectives in Biology is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Proteins of the Triadic Excitation–Contraction Coupling Complex in Skeletal Muscle	206
Teaching School Genetics in the 2020s: Why “Naive” Mendelian Genetics Has to Go	105
The Nodes of Ranvier: Mechanisms of Assembly and Maintenance	103
The Role of Membrane Lipids in the Formation and Function of Caveolae	85
Fisher's Geometric Model as a Tool to Study Speciation	81
Fibroblast Heterogeneity in Healthy and Wounded Skin	79
Nucleotide Metabolism	78
Post-Translational Regulation of HMG CoA Reductase	76
Angiogenesis in Wound Repair: Too Much of a Good Thing?	74
A History of Cancer Research: Retroviral Insertional Mutagenesis	73
The Role of Microhomology-Mediated End Joining (MMEJ) at Dysfunctional Telomeres	68
Petabase-Scale Homology Search for Structure Prediction	65
Telomere Dynamics in Human Health and Disease	64
The Impact of Space and Time on the Functional Output of the Genome	62
Seeing the Membrane from Both Sides Now: Lipid Asymmetry and Its Strange Consequences	58
Engineering Proteins Using Statistical Models of Coevolutionary Sequence Information	58
Diversity of Fibroblasts and Their Roles in Wound Healing	56
Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?	50
Mapping the Retina onto the Brain	49
Modeling Normal and Abnormal Circuit Development with Recurrent Neural Networks	49
Toward Understanding Wound Immunology for High-Fidelity Skin Regeneration	45
Maintaining Telomeres without Telomerase inDrosophila: Novel Mechanisms and Rapid Evolution to Save a Genus	43
Structural Diversity within the Endoplasmic Reticulum—From the Microscale to the Nanoscale	42
Mammalian Digit Tip Regeneration: Moving from Phenomenon to Molecular Mechanism	41
Interneuron Diversity: How Form Becomes Function	41

The Biology of Lipids	41
3D or Not 3D: Shaping the Genome during Development	37
The Nuclear Lamina	37
Building and Maintaining the Skin	37
Endoplasmic Reticulum Membrane Contact Sites, Lipid Transport, and Neurodegeneration	37
A TAle of Two Pathways: Tail-Anchored Protein Insertion at the Endoplasmic Reticulum	34
Lipid Transport from Endoplasmic Reticulum to Autophagic Membranes	34
Good Neighbors: The Niche that Fine Tunes Mammalian Intestinal Regeneration	33
Neotropics as a Cradle for Adaptive Radiations	33
Structure, Maintenance, and Regulation of Nuclear Pore Complexes: The Gatekeepers of the Eukaryotic Genome	31
A History of Cancer Research: Oncogenic Transcription Factors	31
Auxin in Root Development	31
Glial Cell Development and Function in the Zebrafish Central Nervous System	29
Variability in Neural Circuit Formation	28
Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum	27
Why Do Some Lineages Radiate While Others Do Not? Perspectives for Future Research on Adaptive Radiations	27
Combining Molecular, Macroevolutionary, and Macroecological Perspectives on the Generation of Diversity	27
Regulators of Oligodendrocyte Differentiation	26
Inducing Vertebrate Limb Regeneration: A Review of Past Advances and Future Outlook	26
Growth Factor and Cytokine Delivery Systems for Wound Healing	26
Essential Roles for RNA in Shaping Nuclear Organization	25
Predictability, an Orrery, and a Speciation Machine: Quest for a Standard Model of Speciation	25
In the Loop: Unusual DNA Structures at Telomeric Repeats and Their Impact on Telomere Function	25
Sex Differences in Mast Cell–Associated Disorders: A Life Span Perspective	24
Niche Theory as an Underutilized Resource for the Study of Adaptive Radiations	22
Quantitative Analyses of Coupling in Hybrid Zones	21
Polyploidy in Tissue Repair and Regeneration	21
Lipid Metabolism	21
Mechanisms of Chromosome Folding and Nuclear Organization: Their Interplay and Open Questions	21
Transformation of Plantation Forestry Productivity for Climate Change Mitigation and Adaptation	21
Nuclear Compartments: An Incomplete Primer to Nuclear Compartments, Bodies, and Genome Organization Relative to Nuclear Architecture	21
Developmental Control of Cell Cycle and Signaling	20
The Diverse Manifestations of Regeneration and Why We Need to Study Them	20
Evolving Views of Long Noncoding RNAs and Epigenomic Control of Lymphocyte State and Memory	19
Caspases and Their Substrates	19
How Neuromembrane Lipids Modulate Membrane Proteins: Insights from G-Protein-Coupled Receptors (GPCRs) and Receptor Tyrosine Kinases (RTKs)	19
Glia at Transition Zones	18
Development of Prefrontal Circuits and Cognitive Abilities	18
Beyond Fluidity: The Role of Lipid Unsaturation in Membrane Function	18
All for One and One for All: Regenerating Skeletal Muscle	18
Motility Matters: How CD8⁺ T-Cell Trafficking Influences Effector and Memory Cell Differentiation	18
Cholesterol, Eukaryotic Lipid Domains, and an Evolutionary Perspective of Transmembrane Signaling	18
Glia Development and Function in the NematodeCaenorhabditis elegans	18
Pancreatic β-Cell Development and Regeneration	17
Remyelination in the Central Nervous System	17
Synthesis and Scope of the Role of Postmating Prezygotic Isolation in Speciation	17
The Sensory Ecology of Speciation	17