OOIR: Observatory of International Research

Papers

(The TQCC of Cold Spring Harbor Perspectives in Biology is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Teaching School Genetics in the 2020s: Why “Naive” Mendelian Genetics Has to Go	144
Proteins of the Triadic Excitation–Contraction Coupling Complex in Skeletal Muscle	104
Fibroblast Heterogeneity in Healthy and Wounded Skin	99
The Nodes of Ranvier: Mechanisms of Assembly and Maintenance	94
The Role of Membrane Lipids in the Formation and Function of Caveolae	74
Fisher's Geometric Model as a Tool to Study Speciation	66
Post-Translational Regulation of HMG CoA Reductase	57
Angiogenesis in Wound Repair: Too Much of a Good Thing?	55
The Role of Microhomology-Mediated End Joining (MMEJ) at Dysfunctional Telomeres	53
A History of Cancer Research: Retroviral Insertional Mutagenesis	52
Seeing the Membrane from Both Sides Now: Lipid Asymmetry and Its Strange Consequences	51
A Mechanometabolism Toolbox for Studying Cell Migration	47
Engineering Proteins Using Statistical Models of Coevolutionary Sequence Information	46
Telomere Dynamics in Human Health and Disease	45
Petabase-Scale Homology Search for Structure Prediction	42
Regulation of Human Telomerase: from Molecular Interactions to Population Genetics	42
Diversity of Fibroblasts and Their Roles in Wound Healing	42
Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?	41
Modeling Normal and Abnormal Circuit Development with Recurrent Neural Networks	41
Toward Understanding Wound Immunology for High-Fidelity Skin Regeneration	40
Blastocrithidia—A Genetic Alien from the Planet Earth	40
Maintaining Telomeres without Telomerase inDrosophila: Novel Mechanisms and Rapid Evolution to Save a Genus	39
Structural Diversity within the Endoplasmic Reticulum—From the Microscale to the Nanoscale	37
Mapping the Retina onto the Brain	37
Interneuron Diversity: How Form Becomes Function	35

Endoplasmic Reticulum Membrane Contact Sites, Lipid Transport, and Neurodegeneration	34
The Biology of Lipids	33
Neotropics as a Cradle for Adaptive Radiations	33
Lipid Transport from Endoplasmic Reticulum to Autophagic Membranes	32
A TAle of Two Pathways: Tail-Anchored Protein Insertion at the Endoplasmic Reticulum	31
Glial Cell Development and Function in the Zebrafish Central Nervous System	29
Machine Learning for Protein Science and Engineering	29
Variability in Neural Circuit Formation	28
A History of Cancer Research: Oncogenic Transcription Factors	26
Growth Factor and Cytokine Delivery Systems for Wound Healing	26
Combining Molecular, Macroevolutionary, and Macroecological Perspectives on the Generation of Diversity	26
Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum	25
Sticking to Membranes: Structure, Function, and Cellular Roles of the Annexin Family of Ca²⁺- and Membrane-Binding Proteins	25
Why Do Some Lineages Radiate While Others Do Not? Perspectives for Future Research on Adaptive Radiations	25
Cancer Progression and the Calcium Signaling Toolkit: Expanding Dimensions and Perspectives	23
Calcium Signaling and Metabolic Reprogramming in Cancer: Mechanisms and Therapeutic Implications	23
Regulators of Oligodendrocyte Differentiation	23
Niche Theory as an Underutilized Resource for the Study of Adaptive Radiations	22
In the Loop: Unusual DNA Structures at Telomeric Repeats and Their Impact on Telomere Function	22
Predictability, an Orrery, and a Speciation Machine: Quest for a Standard Model of Speciation	22
Sex Differences in Mast Cell–Associated Disorders: A Life Span Perspective	22
Quantitative Analyses of Coupling in Hybrid Zones	21
Transformation of Plantation Forestry Productivity for Climate Change Mitigation and Adaptation	20
Developmental Control of Cell Cycle and Signaling	20
Caspases and Their Substrates	20
How Neuromembrane Lipids Modulate Membrane Proteins: Insights from G-Protein-Coupled Receptors (GPCRs) and Receptor Tyrosine Kinases (RTKs)	20
Beyond Fluidity: The Role of Lipid Unsaturation in Membrane Function	19
The Diverse Manifestations of Regeneration and Why We Need to Study Them	19
Hidden Treasures of the Genetic Systems in Yeast Mitochondria	18
Cholesterol, Eukaryotic Lipid Domains, and an Evolutionary Perspective of Transmembrane Signaling	18
Ca²⁺ Fluxes across Membrane Contact Sites	18
Development of Prefrontal Circuits and Cognitive Abilities	18
Glia at Transition Zones	18
Remyelination in the Central Nervous System	17
Lipid Sorting and Organelle Identity	17
All for One and One for All: Regenerating Skeletal Muscle	17
Glia Development and Function in the NematodeCaenorhabditis elegans	17
Structural Biology of Telomerase and Associated Factors	16
Synthesis and Scope of the Role of Postmating Prezygotic Isolation in Speciation	16
The Sensory Ecology of Speciation	16