OOIR: Observatory of International Research

Papers

(The TQCC of Cold Spring Harbor Perspectives in Biology is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Teaching School Genetics in the 2020s: Why “Naive” Mendelian Genetics Has to Go	192
The Nodes of Ranvier: Mechanisms of Assembly and Maintenance	143
Fisher's Geometric Model as a Tool to Study Speciation	113
Proteins of the Triadic Excitation–Contraction Coupling Complex in Skeletal Muscle	88
Leukocyte Chemotaxis and the Elusive Negative Signals that Make It Work	76
Post-Translational Regulation of HMG CoA Reductase	73
The Role of Membrane Lipids in the Formation and Function of Caveolae	69
Fibroblast Heterogeneity in Healthy and Wounded Skin	69
Angiogenesis in Wound Repair: Too Much of a Good Thing?	69
Engineering Proteins Using Statistical Models of Coevolutionary Sequence Information	67
A History of Cancer Research: Retroviral Insertional Mutagenesis	63
Telomere Dynamics in Human Health and Disease	63
Regulation of Human Telomerase: from Molecular Interactions to Population Genetics	62
Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?	61
Petabase-Scale Homology Search for Structure Prediction	60
A Mechanometabolism Toolbox for Studying Cell Migration	57
The Role of Microhomology-Mediated End Joining (MMEJ) at Dysfunctional Telomeres	57
Diversity of Fibroblasts and Their Roles in Wound Healing	53
Seeing the Membrane from Both Sides Now: Lipid Asymmetry and Its Strange Consequences	53
Modeling Normal and Abnormal Circuit Development with Recurrent Neural Networks	51
Mapping the Retina onto the Brain	51
Toward Understanding Wound Immunology for High-Fidelity Skin Regeneration	51
Roles and Regulation of the Hippo Signaling Pathway in Mammalian Preimplantation Development	49
Blastocrithidia —A Genetic Alien from the Planet Earth	48
Structural Diversity within the Endoplasmic Reticulum—From the Microscale to the Nanoscale	42

Maintaining Telomeres without Telomerase inDrosophila: Novel Mechanisms and Rapid Evolution to Save a Genus	42
Interneuron Diversity: How Form Becomes Function	42
Endoplasmic Reticulum Membrane Contact Sites, Lipid Transport, and Neurodegeneration	40
The Biology of Lipids	39
Neotropics as a Cradle for Adaptive Radiations	39
Lipid Transport from Endoplasmic Reticulum to Autophagic Membranes	38
A TAle of Two Pathways: Tail-Anchored Protein Insertion at the Endoplasmic Reticulum	36
Sticking to Membranes: Structure, Function, and Cellular Roles of the Annexin Family of Ca²⁺- and Membrane-Binding Proteins	35
Machine Learning for Protein Science and Engineering	34
Variability in Neural Circuit Formation	33
Combining Molecular, Macroevolutionary, and Macroecological Perspectives on the Generation of Diversity	33
Chromosome Ends in Motion: Telomeres as Hazards and Hubs in Meiosis	32
Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum	32
Glial Cell Development and Function in the Zebrafish Central Nervous System	32
Why Do Some Lineages Radiate While Others Do Not? Perspectives for Future Research on Adaptive Radiations	31
A History of Cancer Research: Oncogenic Transcription Factors	31
Regulators of Oligodendrocyte Differentiation	31
Growth Factor and Cytokine Delivery Systems for Wound Healing	30
Cancer Progression and the Calcium Signaling Toolkit: Expanding Dimensions and Perspectives	30
Structural Studies of Core Hippo Pathway Components	30
Calcium Signaling and Pathogenesis of Neurodegenerative Disorders: Potential Therapeutic Opportunities	29
Calcium Signaling and Metabolic Reprogramming in Cancer: Mechanisms and Therapeutic Implications	29
Niche Theory as an Underutilized Resource for the Study of Adaptive Radiations	29
In the Loop: Unusual DNA Structures at Telomeric Repeats and Their Impact on Telomere Function	29
Predictability, an Orrery, and a Speciation Machine: Quest for a Standard Model of Speciation	28
Genetically Encoded Ca ²⁺ Sensors	27
Sex Differences in Mast Cell–Associated Disorders: A Life Span Perspective	26
Quantitative Analyses of Coupling in Hybrid Zones	26
How Neuromembrane Lipids Modulate Membrane Proteins: Insights from G-Protein-Coupled Receptors (GPCRs) and Receptor Tyrosine Kinases (RTKs)	25
Telomeres and Telomerase	25
Transformation of Plantation Forestry Productivity for Climate Change Mitigation and Adaptation	25
Soft Matter Physics Meets Cell Biology: Transitions of Collective Cell Migration in 3D Environments	24
Developmental Control of Cell Cycle and Signaling	23
Mechanobiology of the Hippo–YAP Signaling Network	22
Calcium Signaling in Migrating Neutrophils	22
Beyond Fluidity: The Role of Lipid Unsaturation in Membrane Function	22
Ca²⁺ Fluxes across Membrane Contact Sites	21
Glia at Transition Zones	21
Cholesterol, Eukaryotic Lipid Domains, and an Evolutionary Perspective of Transmembrane Signaling	19
Hidden Treasures of the Genetic Systems in Yeast Mitochondria	19
Lipid Sorting and Organelle Identity	19
The Sensory Ecology of Speciation	18
Development of Prefrontal Circuits and Cognitive Abilities	18
Remyelination in the Central Nervous System	18