OOIR: Observatory of International Research

Papers

(The median citation count of Cold Spring Harbor Perspectives in Biology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Auxin Metabolism in Plants	134
Glycolysis	117
Liquid–Liquid Phase Separation in Chromatin	84
Carbohydrate Metabolism	79
Mechanisms of Chromosome Folding and Nuclear Organization: Their Interplay and Open Questions	74
Fourteen Stations of Auxin	67
The Role of Myofibroblasts in Physiological and Pathological Tissue Repair	63
The Mitochondrial Pathway of Apoptosis Part II: The BCL-2 Protein Family	62
Nuclear Compartments: An Incomplete Primer to Nuclear Compartments, Bodies, and Genome Organization Relative to Nuclear Architecture	57
Auxin Plays Multiple Roles during Plant–Pathogen Interactions	56
Endoplasmic Reticulum–Associated Protein Degradation	52
Amino Acid Metabolism	50
The Mitochondrial Pathway of Apoptosis	50
Transcription Factor Dynamics	48
The Death Receptor Pathway of Apoptosis	48
Auxin Transporters—A Biochemical View	47
Physical Nature of Chromatin in the Nucleus	45
Building and Maintaining the Skin	44
Auxin and Flower Development: A Blossoming Field	41
Mechanical Forces in Nuclear Organization	41
Mammalian DNA Replication Timing	40
Mitochondria	40
NADPH—The Forgotten Reducing Equivalent	39
Auxin-Regulated Lateral Root Organogenesis	38
Auxin Interactions with Other Hormones in Plant Development	38

The Nuclear Lamina	37
Memory T-Cell Heterogeneity and Terminology	36
Lipid Metabolism	36
Epigenetic Reprogramming in Early Animal Development	33
Caspases and Their Substrates	33
No Time for Transcription—Rapid Auxin Responses in Plants	32
The Diverse Cellular Functions of Inner Nuclear Membrane Proteins	31
Caspase Activation and Inhibition	31
Insect Gut Regeneration	31
An Essential Function for Auxin in Embryo Development	31
Emerging Properties and Functions of Actin and Actin Filaments Inside the Nucleus	31
Polyploidy in Tissue Repair and Regeneration	30
Regeneration, Rejuvenation, and Replacement: Turning Back the Clock on Tissue Aging	30
Nucleotide Metabolism	28
The Story of Auxin-Binding Protein 1 (ABP1)	28
Comparative Biology of Vertebrate Retinal Regeneration: Restoration of Vision through Cellular Reprogramming	26
Growth Factor and Cytokine Delivery Systems for Wound Healing	26
Structural Aspects of Auxin Signaling	26
Auxin in Root Development	26
Uncovering How Auxin Optimizes Root Systems Architecture in Response to Environmental Stresses	24
ER-Phagy: Quality and Quantity Control of the Endoplasmic Reticulum by Autophagy	24
Sex Differences in Circadian Rhythms	24
Structural Diversity within the Endoplasmic Reticulum—From the Microscale to the Nanoscale	23
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor	22
The Nuclear Pore Complex as a Transcription Regulator	22
Homeostasis of Naive and Memory T Lymphocytes	22
The Molecular and Nuclear Dynamics of X-Chromosome Inactivation	21
The Stochastic Genome and Its Role in Gene Expression	21
Cellular, Metabolic, and Developmental Dimensions of Whole-Body Regeneration in Hydra	21
Endoplasmic Reticulum Membrane Contact Sites, Lipid Transport, and Neurodegeneration	20
Structure and Function of the Nuclear Pore Complex	20
Role of Macrophages in Wound Healing	20
Essential Roles for RNA in Shaping Nuclear Organization	20
Sex Differences in Major Depressive Disorder (MDD) and Preclinical Animal Models for the Study of Depression	19
Metabolism of Proliferating Cells	19
The Biogenesis of Multipass Membrane Proteins	19
Diversity of Fibroblasts and Their Roles in Wound Healing	19
Angiogenesis in Wound Repair: Too Much of a Good Thing?	18
Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum	18
Pervasive Neglect of Sex Differences in Biomedical Research	18
Of Cells, Strands, and Networks: Auxin and the Patterned Formation of the Vascular System	18
Molecular Pathophysiology of Chronic Wounds: Current State and Future Directions	17
The Impact of Chromosomal Rearrangements in Speciation: From Micro- to Macroevolution	17
Auxin Does the SAMba: Auxin Signaling in the Shoot Apical Meristem	16
All for One and One for All: Regenerating Skeletal Muscle	16
Bioelectric Signaling: Role of Bioelectricity in Directional Cell Migration in Wound Healing	16
Uncovering the Principles of Genome Folding by 3D Chromatin Modeling	15
CD8⁺T-Cell Memory: The Why, the When, and the How	15
Positional Information and Stem Cells Combine to Result in Planarian Regeneration	15
Good Neighbors: The Niche that Fine Tunes Mammalian Intestinal Regeneration	15

Chemical Biology in Auxin Research	15
Positional Memory in Vertebrate Regeneration: A Century's Insights from the Salamander Limb	14
Mechanism of Protein Translocation by the Sec61 Translocon Complex	14
Temporal and Epigenetic Control of Plasticity and Fate Decision during CD8⁺T-Cell Memory Differentiation	14
Endoplasmic Reticulum Architecture and Inter-Organelle Communication in Metabolic Health and Disease	14
Sorting and Export of Proteins at the Endoplasmic Reticulum	14
CD4⁺ Memory T-Cell Formation during Type 1 Immune Responses	14
Plasticity of Epithelial Cells during Skin Wound Healing	14
Beyond Fluidity: The Role of Lipid Unsaturation in Membrane Function	14
Fibroblast Heterogeneity in Healthy and Wounded Skin	13
Axon Regeneration: A Subcellular Extension in Multiple Dimensions	13
Computational Models of Auxin-Driven Patterning in Shoots	13
Influenza-Specific Lung-Resident Memory CD8⁺T Cells	13
Signaling and Metabolism	13
Chromatin Mechanisms Driving Cancer	13
3D or Not 3D: Shaping the Genome during Development	12
The Impact of Space and Time on the Functional Output of the Genome	12
On the Evolutionary Origins of Land Plant Auxin Biology	12
Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?	12
Keloid Disorder: Genetic Basis, Gene Expression Profiles, and Immunological Modulation of the Fibrotic Processes in the Skin	12
Cholesterol Transport to the Endoplasmic Reticulum	12
The Ecology of Hybrid Incompatibilities	11
Structure, Maintenance, and Regulation of Nuclear Pore Complexes: The Gatekeepers of the Eukaryotic Genome	11
Cell Death and Cancer	11
A History of Cancer Research: Tumor Viruses	11
Imaging Organization of RNA Processing within the Nucleus	11
Formation of Tissue-Resident CD8⁺ T-Cell Memory	11
Somatic Lineage Reprogramming	11
Sex Differences in Acute Neuroendocrine Responses to Stressors in Rodents and Humans	11
A TAle of Two Pathways: Tail-Anchored Protein Insertion at the Endoplasmic Reticulum	10
Sex Differences in Spotted Hyenas	10
Decoding Tissue-Residency: Programming and Potential of Frontline Memory T Cells	10
Beyond the Code: Noncoding RNAs in Skin Wound Healing	10
Durable CD4 T-Cell Memory Generation Depends on Persistence of High Levels of Infection at an Effector Checkpoint that Determines Multiple Fates	10
Mesenchymal Stem Cell–Derived Extracellular Vesicles as an Advanced Therapy for Chronic Wounds	10
The Wound Microbiome	10
Modeling Auxin Signaling in Roots: Auxin Computations	10
Epithelial–Mesenchymal Plasticity and Endothelial–Mesenchymal Transition in Cutaneous Wound Healing	10
Auxin Biology in Bryophyta: A Simple Platform with Versatile Functions	10
Pancreatic β-Cell Development and Regeneration	9
Mechanisms of Intrinsic Postzygotic Isolation: From Traditional Genic and Chromosomal Views to Genomic and Epigenetic Perspectives	9
Auxin–Environment Integration in Growth Responses to Forage for Resources	9
Cellular Senescence in Acute and Chronic Wound Repair	9
Noncanonical Auxin Signaling	9
Viruses in the Nucleus	9
Lung Regeneration: Cells, Models, and Mechanisms	9
The Naming of Memory T-Cell Subsets	9
Features, Fates, and Functions of Oligodendrocyte Precursor Cells	9
Mammalian Digit Tip Regeneration: Moving from Phenomenon to Molecular Mechanism	8
Stairways to Advanced Therapies for Epidermolysis Bullosa	8
AMPylation and Endoplasmic Reticulum Protein Folding Homeostasis	8
Development and Evolution of Thalamocortical Connectivity	8
Intracellular Cholesterol Trafficking	8
Metabolic Control of Memory T-Cell Generation and Stemness	8
Wound Healing Insights from Flies and Fish	7
Basics of Metabolic Reactions	7
Post-Translational Regulation of HMG CoA Reductase	7
The Membrane Phase Transition Gives Rise to Responsive Plasma Membrane Structure and Function	7
Evolutionary Aspects of the Unfolded Protein Response	7
Cargo Receptor-Mediated ER Export in Lipoprotein Secretion and Lipid Homeostasis	7
Homeostasis and Durability of T-Cell Memory—The Resting and the Restless T-Cell Memory	7
Imaginal Disc Regeneration: Something Old, Something New	7
Inflammasomes and Other Caspase-Activation Platforms	6
Wound-Induced Hair Neogenesis: A Portal to the Development of New Therapies for Hair Loss and Wound Regeneration	6
Engineering Immunomodulatory Biomaterials to Drive Skin Wounds toward Regenerative Healing	6
Intrinsic Networks Regulating Tissue Repair: Comparative Studies of Oral and Skin Wound Healing	6
Motility Matters: How CD8⁺ T-Cell Trafficking Influences Effector and Memory Cell Differentiation	6
The Role of Membrane Lipids in the Formation and Function of Caveolae	6
Lipid Transport from Endoplasmic Reticulum to Autophagic Membranes	6
Structural Variants and Speciation: Multiple Processes at Play	6