OOIR: Observatory of International Research

Papers

(The H4-Index of Oxidative Medicine and Cellular Longevity is 60. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine	303
The Role of Oxidative Stress and Antioxidants in Diabetic Wound Healing	259
Melatonin Suppresses Ferroptosis Induced by High Glucose via Activation of the Nrf2/HO-1 Signaling Pathway in Type 2 Diabetic Osteoporosis	237
The Keap1‐Nrf2 System: A Mediator between Oxidative Stress and Aging	224
A Common Feature of Pesticides: Oxidative Stress—The Role of Oxidative Stress in Pesticide-Induced Toxicity	166
Reactive Oxygen Species (ROS) Regulates Different Types of Cell Death by Acting as a Rheostat	143
Effects and Mechanisms of Resveratrol on Aging and Age‐Related Diseases	143
Genistein: An Integrative Overview of Its Mode of Action, Pharmacological Properties, and Health Benefits	130
Role of Oxidative Stress in Reperfusion following Myocardial Ischemia and Its Treatments	125
Curcumin Ameliorates White Matter Injury after Ischemic Stroke by Inhibiting Microglia/Macrophage Pyroptosis through NF‐κB Suppression and NLRP3 Inflammasome Inhibition	118
Oxidative Stress‐Related Mechanisms in Schizophrenia Pathogenesis and New Treatment Perspectives	115
Posttranslational Modifications in Ferroptosis	114
Flavonols and Flavones as Potential anti-Inflammatory, Antioxidant, and Antibacterial Compounds	108
Targeting Mitochondrial Biogenesis with Polyphenol Compounds	106
Lycopene: Food Sources, Biological Activities, and Human Health Benefits	105
Paclitaxel: Application in Modern Oncology and Nanomedicine‐Based Cancer Therapy	104
RSL3 Drives Ferroptosis through NF‐κB Pathway Activation and GPX4 Depletion in Glioblastoma	101
Targeting Ferroptosis: Pathological Mechanism and Treatment of Ischemia‐Reperfusion Injury	95
Transcriptome Investigation and In Vitro Verification of Curcumin-Induced HO-1 as a Feature of Ferroptosis in Breast Cancer Cells	91
Antioxidants Targeting Mitochondrial Oxidative Stress: Promising Neuroprotectants for Epilepsy	89
The Role of Oxidative Stress in Hypertensive Disorders of Pregnancy (Preeclampsia, Gestational Hypertension) and Metabolic Disorder of Pregnancy (Gestational Diabetes Mellitus)	88
The Protective Effect of Cyanidin‐3‐Glucoside on Myocardial Ischemia‐Reperfusion Injury through Ferroptosis	88
Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential	88
The Therapeutic Effects and Mechanisms of Quercetin on Metabolic Diseases: Pharmacological Data and Clinical Evidence	86
A Marine Terpenoid, Heteronemin, Induces Both the Apoptosis and Ferroptosis of Hepatocellular Carcinoma Cells and Involves the ROS and MAPK Pathways	86

Natural Coumarins: Exploring the Pharmacological Complexity and Underlying Molecular Mechanisms	85
Reactive Oxygen Species and Their Involvement in Red Blood Cell Damage in Chronic Kidney Disease	85
Ferroportin‐Dependent Iron Homeostasis Protects against Oxidative Stress‐Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo	85
Therapeutic Potential of Isoflavones with an Emphasis on Daidzein	85
Crosstalk between Oxidative Stress and Ferroptosis/Oxytosis in Ischemic Stroke: Possible Targets and Molecular Mechanisms	80
Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review	80
Insight into Crosstalk between Ferroptosis and Necroptosis: Novel Therapeutics in Ischemic Stroke	80
Bavachin Induces Ferroptosis through the STAT3/P53/SLC7A11 Axis in Osteosarcoma Cells	80
Mitochondria-Targeted Antioxidants: A Step towards Disease Treatment	78
Classical Active Ingredients and Extracts of Chinese Herbal Medicines: Pharmacokinetics, Pharmacodynamics, and Molecular Mechanisms for Ischemic Stroke	78
Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives	78
Oxidative Stress in Ischemic Heart Disease	74
Combating Oxidative Stress and Inflammation in COVID‐19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives	73
Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention	73
RNA and Oxidative Stress in Alzheimer’s Disease: Focus on microRNAs	72
Plant‐Based Synthesis of Zinc Oxide Nanoparticles (ZnO‐NPs) Using Aqueous Leaf Extract of Aquilegia pubiflora: Their Antiproliferative Activity against HepG2 Cells Inducing Reactive Oxygen Spec	71
Hepcidin Promoted Ferroptosis through Iron Metabolism which Is Associated with DMT1 Signaling Activation in Early Brain Injury following Subarachnoid Hemorrhage	71
Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID‐19—Mechanisms and Therapeutic Targets	71
Heat Shock Proteins in Oxidative Stress and Ischemia/Reperfusion Injury and Benefits from Physical Exercises: A Review to the Current Knowledge	70
The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents	70
The Involvement of the Oxidative Stress Status in Cancer Pathology: A Double View on the Role of the Antioxidants	69
Ophiopogonin D Increases SERCA2a Interaction with Phospholamban by Promoting CYP2J3 Upregulation	69
Dietary Fiber: An Opportunity for a Global Control of Hyperlipidemia	67
Human Umbilical Cord Mesenchymal Stem Cell‐Derived Exosomes Attenuate Oxygen‐Glucose Deprivation/Reperfusion‐Induced Microglial Pyroptosis by Promoting FOXO3a‐Dependent Mitophagy	64
Protective Effects of Estrogen on Cardiovascular Disease Mediated by Oxidative Stress	64
Oxidative Stress, Neuroinflammation, and NADPH Oxidase: Implications in the Pathogenesis and Treatment of Alzheimer’s Disease	64
Astragaloside IV Alleviates Cerebral Ischemia‐Reperfusion Injury through NLRP3 Inflammasome‐Mediated Pyroptosis Inhibition via Activating Nrf2	64
The Role of Oxidative Stress in the Pathogenesis of Vitiligo: A Culprit for Melanocyte Death	63
The Role of Oxidative Stress in Intervertebral Disc Degeneration	62
A Review on Oxidative Stress, Diabetic Complications, and the Roles of Honey Polyphenols	62
SFRP2 Improves Mitochondrial Dynamics and Mitochondrial Biogenesis, Oxidative Stress, and Apoptosis in Diabetic Cardiomyopathy	61
Quercetin Improves Cardiomyocyte Vulnerability to Hypoxia by Regulating SIRT1/TMBIM6‐Related Mitophagy and Endoplasmic Reticulum Stress	61
The Molecular Mechanisms of Regulating Oxidative Stress-Induced Ferroptosis and Therapeutic Strategy in Tumors	61
Neuroprotective Phytochemicals in Experimental Ischemic Stroke: Mechanisms and Potential Clinical Applications	60
Chicoric Acid Ameliorates Nonalcoholic Fatty Liver Disease via the AMPK/Nrf2/NFκB Signaling Pathway and Restores Gut Microbiota in High-Fat-Diet-Fed Mice	60
[Retracted] Alleviation of Inflammation and Oxidative Stress in Pressure Overload‐Induced Cardiac Remodeling and Heart Failure via IL‐6/STAT3 Inhibition by Raloxifene	60