OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Cardiovascular Translational Research is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Morphology Optimization of Leaflet for Surgical Reconstruction of the Aortic Valve: In Vitro Test and Simulation-Based DOE Study	41
Validity and Reproducibility of the Six-Minute Stepper Test in Cardiac Patients	40
Angiography-Derived Coronary Flow Reserve for Integrated Assessment of Coronary Physiology	34
Response to Editorial Note: "Epigenetic Control of Cardiomyocyte Necrosis: Targeting ACSS2 to Attenuate Myocardial Ischemia/Reperfusion Injury"	27
Optimizing Culotte Technique With Double Kissing Balloon Inflation	26
Intrapericardial Administration to Achieve Localized and Targeted Treatment for Cardiac Disease	24
Network Medicine-Based Repurposing of Mesalazine for Atherosclerosis Treatment	23
Transplantation of Human Embryonic Stem Cell–Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia	23
Correction to: Evaluation of a Rabbit Model of Vascular Stent Healing: Application of Optical Coherence Tomography	22
NO-Donation Increases Visceral Circulation in a Porcine Model of Abdominal Hypertension	22
FGF21 Blunts Cardiac Ischemia/Reperfusion Injury by Promoting Autophagic Flux Via Stat1/Irgm1 Pathway	22
The Genetic Factors Influencing Cardiomyopathies and Heart Failure across the Allele Frequency Spectrum	21
PPARγ Agonist Rosiglitazone and Antagonist GW9662: Antihypertensive Effects on Chronic Intermittent Hypoxia-Induced Hypertension in Rats	20
Sustained Mechanical Occlusion of the Superior Vena Cava Safely Reduces Cardiac Filling Pressures in a Preclinical Model of Heart Failure	20
Heart Failure with Recovered Ejection Fraction in Patients with Vinculin Loss-of-function Variants	20
High-intensity Focused Ultrasound-A New Choice to Conduct Pulmonary Artery Denervation	17
Harnessing the Plasma Proteome to Mirror Current and Predict Future Cardiac Remodeling After Myocardial Infarction	17
Mechanical and Geometric Characterization of a Novel 2-Ply Vacuum-Pressed Biological Scaffold Patch Design for Posterior Mitral Valve Reconstruction	16
Wearables in Cardiovascular Disease	16
The Role of Mitophagy in Cardiac Metabolic Remodeling of Heart Failure: Insights of Molecular Mechanisms and Therapeutic Prospects	16
The Prognostic Role of Cortisol and Glucose Dynamics in Cardiogenic Shock-Insights from a Prospective Observational Cohort	16
Danlou Tablet Protects Against Cardiac Remodeling and Dysfunction after Myocardial Ischemia/Reperfusion Injury through Activating AKT/FoxO3a Pathway	16
RNA Therapies in Cardio-Kidney-Metabolic Syndrome: Advancing Disease Management	16
Clinical Impact of the Endo-aortic Clamp for Redo Mitral Valve Surgery	16
Impact of E-Cigarette Use on Circadian Proteins and Cardiovascular Risk Markers	15

Mechanistic Insights into Therapeutic Strategies for Post- Menopausal Atherosclerosis: Evidence from an Ovariectomized Mouse Model	15
Modeling the Hemodynamic Impact of Y-incision Aortic Annular Enlargements on Aortic Valve Replacement and Valve-in-Valve Procedures	15
Machine Learning-Driven Identification of Blood-Based Biomarkers and Therapeutic Agents for Personalized Ischemic Stroke Management	15
Reply to Correspondence on “Absence of Myocardial Involvement after SARS-CoV-2 Vaccination in Asymptomatic Adolescents”	14
Eosinophil Recovery Time Is Associated with Clinical Outcomes in Patients with Type A Acute Aortic Dissection: a Retrospective Cohort Study	14
Intra-aortic and Intra-caval Balloon Pump Devices in Experimental Non-traumatic Cardiac Arrest and Cardiopulmonary Resuscitation	14
Role of Flow-Sensitive Endothelial Genes in Atherosclerosis and Antiatherogenic Therapeutics Development	13
Leukocyte Extracellular Vesicles Predict Progression of Systolic Dysfunction in Heart Failure with Mildly Reduced Ejection Fraction (LYCHEE) – A Prospective, Multicentre Cohort Study	13
Takotsubo Syndrome: The First Non-Acute Proteomic Analysis by Remote Dried Blood Microsampling	13
A New Aspect of Penehyclidine Hydrochloride in Alleviating Myocardial Ischemia–Reperfusion Injury: Ferroptosis	13
The Pathobiology of Interleukin 11 in Mammalian Disease is Likely Explained by its Essential Evolutionary Role for Fin Regeneration	13
The Role of Methylation in Ferroptosis	13
The Microbial Mechanisms of Cardiovascular Disease: Oral Dysbiosis as a Systemic Instigator	12
Silencing DOCK2 Attenuates Cardiac Fibrosis Following Myocardial Infarction in Mice Via Targeting PI3K/Akt and Wnt/β-Catenin Pathways	12
An Animal Model of Functional Tricuspid Regurgitation by Leaflet Tethering Using Image-Guided Chordal Encircling Snares	12
Baicalin Attenuates Oxidative Stress and Apoptosis in Myocardial Ischemia/reperfusion Injury via Suppression of STING/NLRP3 Pathway	12
Diagnostic Value and Short-Term Prognosis Assessment of Copeptin in Non-ST-Elevation Acute Coronary Syndrome	12
A Novel Dual Latex Balloon Catheter for Temporarily Closing Acute Postinfarction Ventricle Septum Defect (VSD) in a Pig Model	11
Chitinase-3-like Protein 1 Reduces the Stability of Atherosclerotic Plaque via Impairing Macrophagic Efferocytosis	11
The Role of ADAM17 in Inflammation-Related Atherosclerosis	11
Abdominal Aortic Aneurysm Formation: a Yap’s View	11
The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity	11
From Energy Metabolic Change to Precision Therapy: a Holistic View of Energy Metabolism in Heart Failure	11
Study of The Relationship Between Differential Small Molecule Peptides in Peripheral Blood and Arteriosclerosis in Patients with Essential Hypertension	11
Ferrostatin-1 Blunts Right Ventricular Hypertrophy and Dysfunction in Pulmonary Arterial Hypertension by Suppressing the HMOX1/GSH Signaling	11
High-Density Lipoprotein: a Molecule-Modulating Angiogenesis	11
Inhibition of Egr2 Protects against TAC-induced Heart Failure in Mice by Suppressing Inflammation and Apoptosis Via Targeting Acot1 in Cardiomyocytes	10
Des-Aspartate Angiotensin-1: A Dual-Targeted Therapeutic for Perivascular Inflammation and Vascular Dysfunction in Obesity	10
Cardiac Overexpression of Chil1 Improves Wound Healing to Prevent Cardiac Rupture After Myocardial Infarction	10
Irisin Regulates Cardiac Responses to Exercise in Health and Diseases: a Narrative Review	10
Translational Methods for Wearable Heart Rate Variability Monitoring in Older Adults: Preoperative Risk Stratification and Postoperative Monitoring	10
Extracellular Vesicles as Diagnostic Metrics for Cardiovascular Disease: Where We are and How to Achieve in Clinics	10
Machine Learning-based Prediction of Temporal Velocity-Informatics (TVI) Variables for Accelerated Characterization of Intracranial Aneurysms’ Rupture Status	10
Platelet microRNA Expression Can Predict Bleeding in HeartMate3 Patients Treated With or Without Aspirin	10
Impact of Myocardial Fibrosis on Cardiovascular Structure, Function and Functional Status in Heart Failure with Preserved Ejection Fraction	10
A Molecular Perspective on the Intricate Interplay Among Exosomes, Bioenergetic Metabolism, and the Pathogenesis of Diabetic Cardiomyopathy	10
Advances in Glycolysis Metabolism of Atherosclerosis	9
Remote Ischemic Conditioning Mediates Cardio-protection After Myocardial Ischemia/Reperfusion Injury by Reducing 4-HNE Levels and Regulating Autophagy via the ALDH2/SIRT3/HIF1α Signaling Pathway	9
Targeting Canonical Wnt-signaling Through GSK-3β in Arrhythmogenic Cardiomyopathy: Conservative or Progressive?	9
CRISPR/Cas9 Mediated Deletion of the Uox Gene Generates a Mouse Model of Hyperuricemia with Multiple Complications	9
Analysis of Correlation Between Coronary Heart Disease and Genetic Polymorphism Detected by Gold Magnetic Nanoparticles Chromatography	9
Single-Cell Sequencing Identifies the Crucial Role of Mitochondrial Fission–Fusion Imbalance in Heart Failure Progression	9
Circulating Extracellular Vesicles Predict Complications after Cardiac Surgery	9
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia	9
Preclinical Assessment of a Novel Polymer-Free Hybrid Drug Eluting Stent	9
Lacylation of Stearoyl-CoA Desaturase-1 Contributes to the Myocardial Ischemia–Reperfusion Injury Through Regulating Wnt/β-Catenin Signaling	9
Correlation Between NLR to Albumin Ratio and 90-day Prognosis After Treatment for Acute Ischemic Stroke	9
TAVI Under Pressure: Intra-balloon Pressure Profiles During Balloon-Expandable TAVR—First Data from a Feasibility Study	8
Gene Therapy for Inherited Cardiac Arrhythmias	8
DDX17: A Potential Target for Heart Failure Therapies	8

Intravascular Ultrasound-Based Fractional Flow Reserve for Predicting Prognosis after Percutaneous Coronary Intervention	8
ALDH2/eIF3E as Novel Regulators of Cardiac Ferroptosis	8
Microcirculatory Monitoring in Children with Congenital Heart Disease Before and After Cardiac Surgery	8
CRISPR-Cas9 Targeting PCSK9: A Promising Therapeutic Approach for Atherosclerosis	8
Gut Microbiota as Predictive Biomarker for Chronic Heart Failure in Patients with Different Nutritional Risk	8
Gene Therapies in Atrial Fibrillation	8
TMAO Impairs Mouse Aortic Vasodilation by Inhibiting TRPV4 Channels in Endothelial Cells	8
Cardiac Metabolism, Reprogramming, and Diseases	7
Inhibition of Hsp90 K284 Acetylation Aalleviates Cardiac Injury After Ischemia–Reperfusion Injury	7
Postconditioning with Lactate-Enriched Blood for Reducing Lethal Reperfusion Injury in Humans	7
Association Between Automated 3D Measurement of Coronary Luminal Narrowing and Risk of Future Myocardial Infarction	7
Automated Data Transformation and Feature Extraction for Oxygenation-Sensitive Cardiovascular Magnetic Resonance Images	7
The Role of Gut Microbiota and Trimethylamine N-oxide in Cardiovascular Diseases	7
Targeting Vascular Smooth Muscle Cell Senescence: A Novel Strategy for Vascular Diseases	7
Hif-1α/Slit2 Mediates Vascular Smooth Muscle Cell Phenotypic Changes in Restenosis of Bypass Grafts	7
Emerging Paradigms in Atherosclerosis: The Impact of LncRNA PSMB8-AS1 on Vascular Inflammation and Plaque Formation	7
CNDP2: An Enzyme Linking Metabolism and Cardiovascular Diseases?	7
CD4+ Treg: A Novel Player in Cardiac Regenerative Therapy	7
Optimization of Strategy for Modified mRNA Inducing Cardiac-Specific Expression in Mice	7
Normoxemic Extracorporeal Membrane Oxygenation Reduces Infarct Size and Preserves Mitochondrial Integrity in Preclinical Models of Acute Myocardial Infarction	7
Past Trends and Future Directions of Cardiac Regenerative Medicine – A Systematic Analysis of Clinical Trial Registries	7
Correction to: LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide	7
Cellular and Extracellular Non-coding RNAs in Cardiac Physiology and Diseases	7
The Effect of Extracellular Vesicles on Thrombosis	7
Chronic Oxidative Stress as a Marker of Long-term Radiation-Induced Cardiovascular Outcomes in Breast Cancer	7
Connecting the Dots: Stress Granule and Cardiovascular Diseases	7
Non-Coding RNA-Mediated Gene Regulation in Cardiovascular Disorders: Current Insights and Future Directions	7
Cardiac Magnetic Resonance-Derived Left Ventricular Mechanical Dispersion Improves Risk Stratification of Hypertrophic Cardiomyopathy and its Correlations with Scar Heterogeneity	7
p16INK4a Aggravated Sepsis-associated Cardiac Injury by Inhibiting the PI3K/AKT Pathway and Inducing Redox Imbalance	7
Exploration of the Potential Biomarker FNDC5 for Discriminating Heart Failure in Patients with Coronary Atherosclerosis	7
Identification of Gravida Serum Biomarkers for Noninvasive Prenatal Diagnosis Fetal Congenital Heart Disease	7
New Insights into the Genetics of Cardiomyopathies	7
Inflammatory profiles define phenotypes with clinical relevance in acute type A aortic dissection	6
T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease	6
The Role of Testosterone in Atherosclerosis: View From Cell Cultures and Animal Models	6
The Clinical Significance of miR-139-5p in Acute Coronary Syndrome and its Potential Effect on the Progression of Acute Coronary Syndrome	6
Long-Term Training Increases Atrial Fibrillation Sustainability in Standardbred Racehorses	6
Silent Myocardial Infarction Revisited: Immuno-metabolic Mechanisms, Multimodal Biomarkers, and Translational Diagnostics	6
Exosomal miRNAs: A New Frontier in Cardiovascular Disease Diagnosis and Treatment	6
Harnessing Electronic Medical Records in Cardiovascular Clinical Practice and Research	6
LncRNA SMILR Serves a Diagnostic Biomarker in Patients with Chronic Heart Failure and Regulates Functions of Vascular Endothelial Cells	6
Exploratory Study of the Effects of Irreversible Electroporation on Atherosclerotic Plaque in a Rabbit Model	6
CXCR6 Mediates Pressure Overload-Induced Aortic Stiffness by Increasing Macrophage Recruitment and Reducing Exosome-miRNA29b	6
FAM3A As a Potential Molecular Target to Regulate Mitochondrial Respiration and ATP Production in Ischemic Heart	6
Past, Present and Future of Regenerative Gene Therapy for Ischemic Heart Failure	6
The Role of Regulatory T Cells in Heart Repair After Myocardial Infarction	6
Heart Failure with Preserved Ejection Fraction: Pathogenesis, Diagnosis, Exercise, and Medical Therapies	6
Knockdown of Mmu-circ-0001380 Attenuates Myocardial Ischemia/Reperfusion Injury via Modulating miR-106b-5p/Phlpp2 Axis	6
Senescence-related Genes as Prognostic Markers for STEMI Patients: LASSO Regression-Based Bioinformatics and External Validation	6
Molecular Pathways of Endothelial Dysfunction Induced by Chronic Social Stress and Therapeutic Interventions	6
Percutaneous Alginate Hydrogel Endomyocardial Injection with a Novel Dedicated Catheter Delivery System: An Animal Feasibility Study	6
Predictors of Myocardial Ischemia in Patients with Kawasaki Disease: Insights from Patient-Specific Simulations of Coronary Hemodynamics	6
Comment on “A Potential Ratio for Detecting Subclinical Atherosclerosis: Insight into Advanced NMR Lipid Profiles in Severe Obesity”	6
The Fibrinogen-to-Albumin Ratio Is Associated with Poor Prognosis in Patients with Coronary Artery Disease: Findings from a Large Cohort	6
Metabolomic Profiling for Predicting Coronary Artery Aneurysms and IVIG Resistance in Kawasaki Disease- An Exploratory Study	6
LncRNA HDAC11-AS1 Suppresses Atherosclerosis by Inhibiting HDAC11-Mediated Adropin Histone Deacetylation	6
Plasma Biomarker Screening Based on Proteomic Signature of Patients with Resistant Hypertension	6