OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Cardiovascular Translational Research is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Validity and Reproducibility of the Six-Minute Stepper Test in Cardiac Patients	50
Angiography-Derived Coronary Flow Reserve for Integrated Assessment of Coronary Physiology	41
Response to Editorial Note: "Epigenetic Control of Cardiomyocyte Necrosis: Targeting ACSS2 to Attenuate Myocardial Ischemia/Reperfusion Injury"	35
Optimizing Culotte Technique With Double Kissing Balloon Inflation	28
Transplantation of Human Embryonic Stem Cell–Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia	25
Sustained Mechanical Occlusion of the Superior Vena Cava Safely Reduces Cardiac Filling Pressures in a Preclinical Model of Heart Failure	24
Correction to: Evaluation of a Rabbit Model of Vascular Stent Healing: Application of Optical Coherence Tomography	24
FGF21 Blunts Cardiac Ischemia/Reperfusion Injury by Promoting Autophagic Flux Via Stat1/Irgm1 Pathway	24
NO-Donation Increases Visceral Circulation in a Porcine Model of Abdominal Hypertension	23
Network Medicine-Based Repurposing of Mesalazine for Atherosclerosis Treatment	23
Heart Failure with Recovered Ejection Fraction in Patients with Vinculin Loss-of-function Variants	23
Intrapericardial Administration to Achieve Localized and Targeted Treatment for Cardiac Disease	22
The Genetic Factors Influencing Cardiomyopathies and Heart Failure across the Allele Frequency Spectrum	20
High-intensity Focused Ultrasound-A New Choice to Conduct Pulmonary Artery Denervation	19
Harnessing the Plasma Proteome to Mirror Current and Predict Future Cardiac Remodeling After Myocardial Infarction	19
Danlou Tablet Protects Against Cardiac Remodeling and Dysfunction after Myocardial Ischemia/Reperfusion Injury through Activating AKT/FoxO3a Pathway	18
Clinical Impact of the Endo-aortic Clamp for Redo Mitral Valve Surgery	17
Impact of E-Cigarette Use on Circadian Proteins and Cardiovascular Risk Markers	17
The Prognostic Role of Cortisol and Glucose Dynamics in Cardiogenic Shock-Insights from a Prospective Observational Cohort	17
RNA Therapies in Cardio-Kidney-Metabolic Syndrome: Advancing Disease Management	17
Intra-aortic and Intra-caval Balloon Pump Devices in Experimental Non-traumatic Cardiac Arrest and Cardiopulmonary Resuscitation	17
Eosinophil Recovery Time Is Associated with Clinical Outcomes in Patients with Type A Acute Aortic Dissection: a Retrospective Cohort Study	17
PPARγ Agonist Rosiglitazone and Antagonist GW9662: Antihypertensive Effects on Chronic Intermittent Hypoxia-Induced Hypertension in Rats	16
The Role of Mitophagy in Cardiac Metabolic Remodeling of Heart Failure: Insights of Molecular Mechanisms and Therapeutic Prospects	16
Mechanical and Geometric Characterization of a Novel 2-Ply Vacuum-Pressed Biological Scaffold Patch Design for Posterior Mitral Valve Reconstruction	16

Modeling the Hemodynamic Impact of Y-incision Aortic Annular Enlargements on Aortic Valve Replacement and Valve-in-Valve Procedures	16
Machine Learning-Driven Identification of Blood-Based Biomarkers and Therapeutic Agents for Personalized Ischemic Stroke Management	15
Left Ventricular Thrombus in Ischemic Heart Failure: Machine-learning–based Prediction of Six-month Persistence and One-year Outcomes	15
Wearables in Cardiovascular Disease	14
A New Aspect of Penehyclidine Hydrochloride in Alleviating Myocardial Ischemia–Reperfusion Injury: Ferroptosis	14
Reply to Correspondence on “Absence of Myocardial Involvement after SARS-CoV-2 Vaccination in Asymptomatic Adolescents”	14
Role of Flow-Sensitive Endothelial Genes in Atherosclerosis and Antiatherogenic Therapeutics Development	14
Association between Cognitive Function and Postoperative Stroke Following Off-Pump Coronary Artery Bypass Grafting	14
Mechanistic Insights into Therapeutic Strategies for Post- Menopausal Atherosclerosis: Evidence from an Ovariectomized Mouse Model	14
The Role of Methylation in Ferroptosis	14
Baicalin Attenuates Oxidative Stress and Apoptosis in Myocardial Ischemia/reperfusion Injury via Suppression of STING/NLRP3 Pathway	13
Silencing DOCK2 Attenuates Cardiac Fibrosis Following Myocardial Infarction in Mice Via Targeting PI3K/Akt and Wnt/β-Catenin Pathways	13
Takotsubo Syndrome: The First Non-Acute Proteomic Analysis by Remote Dried Blood Microsampling	13
The Pathobiology of Interleukin 11 in Mammalian Disease is Likely Explained by its Essential Evolutionary Role for Fin Regeneration	12
An Animal Model of Functional Tricuspid Regurgitation by Leaflet Tethering Using Image-Guided Chordal Encircling Snares	12
The Microbial Mechanisms of Cardiovascular Disease: Oral Dysbiosis as a Systemic Instigator	12
A Novel Dual Latex Balloon Catheter for Temporarily Closing Acute Postinfarction Ventricle Septum Defect (VSD) in a Pig Model	11
PSAP Protects Against Acute Myocardial Ischemia–Reperfusion Injury by Promoting ASAH1-Mediated Ceramide Metabolism	11
The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity	11
Platelet microRNA Expression Can Predict Bleeding in HeartMate3 Patients Treated With or Without Aspirin	11
Study of The Relationship Between Differential Small Molecule Peptides in Peripheral Blood and Arteriosclerosis in Patients with Essential Hypertension	11
Ferrostatin-1 Blunts Right Ventricular Hypertrophy and Dysfunction in Pulmonary Arterial Hypertension by Suppressing the HMOX1/GSH Signaling	11
Irisin Regulates Cardiac Responses to Exercise in Health and Diseases: a Narrative Review	11
Leukocyte Extracellular Vesicles Predict Progression of Systolic Dysfunction in Heart Failure with Mildly Reduced Ejection Fraction (LYCHEE) – A Prospective, Multicentre Cohort Study	11
Des-Aspartate Angiotensin-1: A Dual-Targeted Therapeutic for Perivascular Inflammation and Vascular Dysfunction in Obesity	11
A Molecular Perspective on the Intricate Interplay Among Exosomes, Bioenergetic Metabolism, and the Pathogenesis of Diabetic Cardiomyopathy	11
Cardiac Overexpression of Chil1 Improves Wound Healing to Prevent Cardiac Rupture After Myocardial Infarction	11
Chitinase-3-like Protein 1 Reduces the Stability of Atherosclerotic Plaque via Impairing Macrophagic Efferocytosis	11
Targeting Ferroptosis and Pyroptosis in Cardiovascular Diseases: Mechanisms and Therapeutic Implication	10
Inhibition of Egr2 Protects against TAC-induced Heart Failure in Mice by Suppressing Inflammation and Apoptosis Via Targeting Acot1 in Cardiomyocytes	10
Machine Learning-based Prediction of Temporal Velocity-Informatics (TVI) Variables for Accelerated Characterization of Intracranial Aneurysms’ Rupture Status	10
Diagnostic Value and Short-Term Prognosis Assessment of Copeptin in Non-ST-Elevation Acute Coronary Syndrome	10
From Energy Metabolic Change to Precision Therapy: a Holistic View of Energy Metabolism in Heart Failure	10
Extracellular Vesicles as Diagnostic Metrics for Cardiovascular Disease: Where We are and How to Achieve in Clinics	10
Analysis of Correlation Between Coronary Heart Disease and Genetic Polymorphism Detected by Gold Magnetic Nanoparticles Chromatography	10
Advances in Glycolysis Metabolism of Atherosclerosis	10
High-Density Lipoprotein: a Molecule-Modulating Angiogenesis	10
Translational Methods for Wearable Heart Rate Variability Monitoring in Older Adults: Preoperative Risk Stratification and Postoperative Monitoring	10
Preclinical Assessment of a Novel Polymer-Free Hybrid Drug Eluting Stent	10
Remote Ischemic Conditioning Mediates Cardio-protection After Myocardial Ischemia/Reperfusion Injury by Reducing 4-HNE Levels and Regulating Autophagy via the ALDH2/SIRT3/HIF1α Signaling Pathway	9
Circulating Extracellular Vesicles Predict Complications after Cardiac Surgery	9
Microcirculatory Monitoring in Children with Congenital Heart Disease Before and After Cardiac Surgery	9
CRISPR/Cas9 Mediated Deletion of the Uox Gene Generates a Mouse Model of Hyperuricemia with Multiple Complications	9
Single-Cell Sequencing Identifies the Crucial Role of Mitochondrial Fission–Fusion Imbalance in Heart Failure Progression	9
DDX17: A Potential Target for Heart Failure Therapies	9
TMAO Impairs Mouse Aortic Vasodilation by Inhibiting TRPV4 Channels in Endothelial Cells	9
ALDH2/eIF3E as Novel Regulators of Cardiac Ferroptosis	9
Lacylation of Stearoyl-CoA Desaturase-1 Contributes to the Myocardial Ischemia–Reperfusion Injury Through Regulating Wnt/β-Catenin Signaling	9
Correlation Between NLR to Albumin Ratio and 90-day Prognosis After Treatment for Acute Ischemic Stroke	9
Gut Microbiota as Predictive Biomarker for Chronic Heart Failure in Patients with Different Nutritional Risk	9

Postconditioning with Lactate-Enriched Blood for Reducing Lethal Reperfusion Injury in Humans	8
Connecting the Dots: Stress Granule and Cardiovascular Diseases	8
Gene Therapies in Atrial Fibrillation	8
CNDP2: An Enzyme Linking Metabolism and Cardiovascular Diseases?	8
Normoxemic Extracorporeal Membrane Oxygenation Reduces Infarct Size and Preserves Mitochondrial Integrity in Preclinical Models of Acute Myocardial Infarction	8
Targeting Vascular Smooth Muscle Cell Senescence: A Novel Strategy for Vascular Diseases	8
Chronic Oxidative Stress as a Marker of Long-term Radiation-Induced Cardiovascular Outcomes in Breast Cancer	8
Impact of Microaxial Flow Pump on Coronary Flow Dynamics in Normal Hearts: An Experimental Evaluation	8
Gene Therapy for Inherited Cardiac Arrhythmias	8
Predicting Mortality After Percutaneous Coronary Intervention in a Multiethnic Southeast Asian Population: Insights From Machine Learning	8
Cardiac Metabolism, Reprogramming, and Diseases	8
CD4+ Treg: A Novel Player in Cardiac Regenerative Therapy	8
Targeting Canonical Wnt-signaling Through GSK-3β in Arrhythmogenic Cardiomyopathy: Conservative or Progressive?	8
CRISPR-Cas9 Targeting PCSK9: A Promising Therapeutic Approach for Atherosclerosis	8
Cardiac Magnetic Resonance-Derived Left Ventricular Mechanical Dispersion Improves Risk Stratification of Hypertrophic Cardiomyopathy and its Correlations with Scar Heterogeneity	8
Exploration of the Potential Biomarker FNDC5 for Discriminating Heart Failure in Patients with Coronary Atherosclerosis	7
Non-Coding RNA-Mediated Gene Regulation in Cardiovascular Disorders: Current Insights and Future Directions	7
Past Trends and Future Directions of Cardiac Regenerative Medicine – A Systematic Analysis of Clinical Trial Registries	7
Silent Myocardial Infarction Revisited: Immuno-metabolic Mechanisms, Multimodal Biomarkers, and Translational Diagnostics	7
Emerging Paradigms in Atherosclerosis: The Impact of LncRNA PSMB8-AS1 on Vascular Inflammation and Plaque Formation	7
Inhibition of Hsp90 K284 Acetylation Aalleviates Cardiac Injury After Ischemia–Reperfusion Injury	7
Identification of Gravida Serum Biomarkers for Noninvasive Prenatal Diagnosis Fetal Congenital Heart Disease	7
The Role of Gut Microbiota and Trimethylamine N-oxide in Cardiovascular Diseases	7
Heart Failure with Preserved Ejection Fraction: Pathogenesis, Diagnosis, Exercise, and Medical Therapies	7
Harnessing Electronic Medical Records in Cardiovascular Clinical Practice and Research	7
Association Between Automated 3D Measurement of Coronary Luminal Narrowing and Risk of Future Myocardial Infarction	7
Automated Data Transformation and Feature Extraction for Oxygenation-Sensitive Cardiovascular Magnetic Resonance Images	7
p16INK4a Aggravated Sepsis-associated Cardiac Injury by Inhibiting the PI3K/AKT Pathway and Inducing Redox Imbalance	7
Long-Term Training Increases Atrial Fibrillation Sustainability in Standardbred Racehorses	7
Metabolomic Profiling for Predicting Coronary Artery Aneurysms and IVIG Resistance in Kawasaki Disease- An Exploratory Study	7
Low-dose Empagliflozin Does Not Modify Myocardial Energetics and Function in a Large-animal Model of Hibernating Myocardium	7
Intravascular Ultrasound-Based Fractional Flow Reserve for Predicting Prognosis after Percutaneous Coronary Intervention	7
The Role of Regulatory T Cells in Heart Repair After Myocardial Infarction	6
MiR-378a-3p Promotes Macrophage Polarization from M1 to M2 for Cardiac Repair after Infarction Via Trem1	6
Past, Present and Future of Regenerative Gene Therapy for Ischemic Heart Failure	6
HNMT: A Key Pro-hypertrophic Factor in Pressure Overload	6
Comment on “A Potential Ratio for Detecting Subclinical Atherosclerosis: Insight into Advanced NMR Lipid Profiles in Severe Obesity”	6
Predictors of Myocardial Ischemia in Patients with Kawasaki Disease: Insights from Patient-Specific Simulations of Coronary Hemodynamics	6
FAM3A As a Potential Molecular Target to Regulate Mitochondrial Respiration and ATP Production in Ischemic Heart	6
Correction to: A Novel Hemostatic Belt Allowing Ambulation Soon After Atrial Fibrillation Ablation	6
The Role of Testosterone in Atherosclerosis: View From Cell Cultures and Animal Models	6
Clinical Significance of High-Sensitivity Cardiac Troponin I and Myoglobin in Patients with Suspected Coronary Microvascular Dysfunction	6
Xanthatin Attenuates Angiotensin II-Induced Cardiac Hypertrophy by Targeting CREB5	6
Optimization of Strategy for Modified mRNA Inducing Cardiac-Specific Expression in Mice	6
Knockdown of Mmu-circ-0001380 Attenuates Myocardial Ischemia/Reperfusion Injury via Modulating miR-106b-5p/Phlpp2 Axis	6
New Insights into the Genetics of Cardiomyopathies	6
Senescence-related Genes as Prognostic Markers for STEMI Patients: LASSO Regression-Based Bioinformatics and External Validation	6
Clinical Value of Computational Angiography-derived Fractional Flow Reserve in Stable Coronary Artery Disease	6
Deep Learning Model for Coronary Angiography	6
T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease	6
The Clinical Significance of miR-139-5p in Acute Coronary Syndrome and its Potential Effect on the Progression of Acute Coronary Syndrome	6
Percutaneous Alginate Hydrogel Endomyocardial Injection with a Novel Dedicated Catheter Delivery System: An Animal Feasibility Study	6
Hif-1α/Slit2 Mediates Vascular Smooth Muscle Cell Phenotypic Changes in Restenosis of Bypass Grafts	6
Plasma Biomarker Screening Based on Proteomic Signature of Patients with Resistant Hypertension	6
The Fibrinogen-to-Albumin Ratio Is Associated with Poor Prognosis in Patients with Coronary Artery Disease: Findings from a Large Cohort	6
The Effect of Extracellular Vesicles on Thrombosis	6
Exosomal miRNAs: A New Frontier in Cardiovascular Disease Diagnosis and Treatment	6
Molecular Pathways of Endothelial Dysfunction Induced by Chronic Social Stress and Therapeutic Interventions	6
Inflammatory profiles define phenotypes with clinical relevance in acute type A aortic dissection	6
LncRNA SMILR Serves a Diagnostic Biomarker in Patients with Chronic Heart Failure and Regulates Functions of Vascular Endothelial Cells	6
CXCR6 Mediates Pressure Overload-Induced Aortic Stiffness by Increasing Macrophage Recruitment and Reducing Exosome-miRNA29b	6
Exploratory Study of the Effects of Irreversible Electroporation on Atherosclerotic Plaque in a Rabbit Model	6