OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Cardiovascular Translational Research is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Morphology Optimization of Leaflet for Surgical Reconstruction of the Aortic Valve: In Vitro Test and Simulation-Based DOE Study	43
Validity and Reproducibility of the Six-Minute Stepper Test in Cardiac Patients	41
Angiography-Derived Coronary Flow Reserve for Integrated Assessment of Coronary Physiology	34
Response to Editorial Note: "Epigenetic Control of Cardiomyocyte Necrosis: Targeting ACSS2 to Attenuate Myocardial Ischemia/Reperfusion Injury"	28
Optimizing Culotte Technique With Double Kissing Balloon Inflation	24
Transplantation of Human Embryonic Stem Cell–Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia	23
FGF21 Blunts Cardiac Ischemia/Reperfusion Injury by Promoting Autophagic Flux Via Stat1/Irgm1 Pathway	23
Intrapericardial Administration to Achieve Localized and Targeted Treatment for Cardiac Disease	23
Network Medicine-Based Repurposing of Mesalazine for Atherosclerosis Treatment	23
NO-Donation Increases Visceral Circulation in a Porcine Model of Abdominal Hypertension	22
The Genetic Factors Influencing Cardiomyopathies and Heart Failure across the Allele Frequency Spectrum	20
Correction to: Evaluation of a Rabbit Model of Vascular Stent Healing: Application of Optical Coherence Tomography	20
Sustained Mechanical Occlusion of the Superior Vena Cava Safely Reduces Cardiac Filling Pressures in a Preclinical Model of Heart Failure	20
Harnessing the Plasma Proteome to Mirror Current and Predict Future Cardiac Remodeling After Myocardial Infarction	17
PPARγ Agonist Rosiglitazone and Antagonist GW9662: Antihypertensive Effects on Chronic Intermittent Hypoxia-Induced Hypertension in Rats	17
High-intensity Focused Ultrasound-A New Choice to Conduct Pulmonary Artery Denervation	17
Heart Failure with Recovered Ejection Fraction in Patients with Vinculin Loss-of-function Variants	17
Machine Learning-Driven Identification of Blood-Based Biomarkers and Therapeutic Agents for Personalized Ischemic Stroke Management	16
Danlou Tablet Protects Against Cardiac Remodeling and Dysfunction after Myocardial Ischemia/Reperfusion Injury through Activating AKT/FoxO3a Pathway	16
The Prognostic Role of Cortisol and Glucose Dynamics in Cardiogenic Shock-Insights from a Prospective Observational Cohort	16
Clinical Impact of the Endo-aortic Clamp for Redo Mitral Valve Surgery	16
Intra-aortic and Intra-caval Balloon Pump Devices in Experimental Non-traumatic Cardiac Arrest and Cardiopulmonary Resuscitation	16
Wearables in Cardiovascular Disease	16
Impact of E-Cigarette Use on Circadian Proteins and Cardiovascular Risk Markers	15
Mechanical and Geometric Characterization of a Novel 2-Ply Vacuum-Pressed Biological Scaffold Patch Design for Posterior Mitral Valve Reconstruction	15

RNA Therapies in Cardio-Kidney-Metabolic Syndrome: Advancing Disease Management	15
Eosinophil Recovery Time Is Associated with Clinical Outcomes in Patients with Type A Acute Aortic Dissection: a Retrospective Cohort Study	15
Mechanistic Insights into Therapeutic Strategies for Post- Menopausal Atherosclerosis: Evidence from an Ovariectomized Mouse Model	14
The Pathobiology of Interleukin 11 in Mammalian Disease is Likely Explained by its Essential Evolutionary Role for Fin Regeneration	14
Reply to Correspondence on “Absence of Myocardial Involvement after SARS-CoV-2 Vaccination in Asymptomatic Adolescents”	14
Baicalin Attenuates Oxidative Stress and Apoptosis in Myocardial Ischemia/reperfusion Injury via Suppression of STING/NLRP3 Pathway	14
The Role of Mitophagy in Cardiac Metabolic Remodeling of Heart Failure: Insights of Molecular Mechanisms and Therapeutic Prospects	14
Modeling the Hemodynamic Impact of Y-incision Aortic Annular Enlargements on Aortic Valve Replacement and Valve-in-Valve Procedures	14
The Role of Methylation in Ferroptosis	14
Leukocyte Extracellular Vesicles Predict Progression of Systolic Dysfunction in Heart Failure with Mildly Reduced Ejection Fraction (LYCHEE) – A Prospective, Multicentre Cohort Study	13
A New Aspect of Penehyclidine Hydrochloride in Alleviating Myocardial Ischemia–Reperfusion Injury: Ferroptosis	13
The Microbial Mechanisms of Cardiovascular Disease: Oral Dysbiosis as a Systemic Instigator	12
Role of Flow-Sensitive Endothelial Genes in Atherosclerosis and Antiatherogenic Therapeutics Development	12
An Animal Model of Functional Tricuspid Regurgitation by Leaflet Tethering Using Image-Guided Chordal Encircling Snares	12
Silencing DOCK2 Attenuates Cardiac Fibrosis Following Myocardial Infarction in Mice Via Targeting PI3K/Akt and Wnt/β-Catenin Pathways	12
Platelet microRNA Expression Can Predict Bleeding in HeartMate3 Patients Treated With or Without Aspirin	11
Chitinase-3-like Protein 1 Reduces the Stability of Atherosclerotic Plaque via Impairing Macrophagic Efferocytosis	11
Des-Aspartate Angiotensin-1: A Dual-Targeted Therapeutic for Perivascular Inflammation and Vascular Dysfunction in Obesity	11
Machine Learning-based Prediction of Temporal Velocity-Informatics (TVI) Variables for Accelerated Characterization of Intracranial Aneurysms’ Rupture Status	11
A Novel Dual Latex Balloon Catheter for Temporarily Closing Acute Postinfarction Ventricle Septum Defect (VSD) in a Pig Model	11
Takotsubo Syndrome: The First Non-Acute Proteomic Analysis by Remote Dried Blood Microsampling	11
A Molecular Perspective on the Intricate Interplay Among Exosomes, Bioenergetic Metabolism, and the Pathogenesis of Diabetic Cardiomyopathy	11
Study of The Relationship Between Differential Small Molecule Peptides in Peripheral Blood and Arteriosclerosis in Patients with Essential Hypertension	11
Inhibition of Egr2 Protects against TAC-induced Heart Failure in Mice by Suppressing Inflammation and Apoptosis Via Targeting Acot1 in Cardiomyocytes	10
Irisin Regulates Cardiac Responses to Exercise in Health and Diseases: a Narrative Review	10
Diagnostic Value and Short-Term Prognosis Assessment of Copeptin in Non-ST-Elevation Acute Coronary Syndrome	10
Extracellular Vesicles as Diagnostic Metrics for Cardiovascular Disease: Where We are and How to Achieve in Clinics	10
High-Density Lipoprotein: a Molecule-Modulating Angiogenesis	10
The Role of ADAM17 in Inflammation-Related Atherosclerosis	10
Impact of Myocardial Fibrosis on Cardiovascular Structure, Function and Functional Status in Heart Failure with Preserved Ejection Fraction	10
Cardiac Overexpression of Chil1 Improves Wound Healing to Prevent Cardiac Rupture After Myocardial Infarction	10
From Energy Metabolic Change to Precision Therapy: a Holistic View of Energy Metabolism in Heart Failure	10
Translational Methods for Wearable Heart Rate Variability Monitoring in Older Adults: Preoperative Risk Stratification and Postoperative Monitoring	10
Advances in Glycolysis Metabolism of Atherosclerosis	10
Ferrostatin-1 Blunts Right Ventricular Hypertrophy and Dysfunction in Pulmonary Arterial Hypertension by Suppressing the HMOX1/GSH Signaling	9
Preclinical Assessment of a Novel Polymer-Free Hybrid Drug Eluting Stent	9
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia	9
The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity	9
Remote Ischemic Conditioning Mediates Cardio-protection After Myocardial Ischemia/Reperfusion Injury by Reducing 4-HNE Levels and Regulating Autophagy via the ALDH2/SIRT3/HIF1α Signaling Pathway	9
Gene Therapies in Atrial Fibrillation	9
Analysis of Correlation Between Coronary Heart Disease and Genetic Polymorphism Detected by Gold Magnetic Nanoparticles Chromatography	9
Lacylation of Stearoyl-CoA Desaturase-1 Contributes to the Myocardial Ischemia–Reperfusion Injury Through Regulating Wnt/β-Catenin Signaling	9
Single-Cell Sequencing Identifies the Crucial Role of Mitochondrial Fission–Fusion Imbalance in Heart Failure Progression	9
Circulating Extracellular Vesicles Predict Complications after Cardiac Surgery	8
Gene Therapy for Inherited Cardiac Arrhythmias	8
CRISPR/Cas9 Mediated Deletion of the Uox Gene Generates a Mouse Model of Hyperuricemia with Multiple Complications	8
Microcirculatory Monitoring in Children with Congenital Heart Disease Before and After Cardiac Surgery	8
Targeting Canonical Wnt-signaling Through GSK-3β in Arrhythmogenic Cardiomyopathy: Conservative or Progressive?	8
DDX17: A Potential Target for Heart Failure Therapies	8
TMAO Impairs Mouse Aortic Vasodilation by Inhibiting TRPV4 Channels in Endothelial Cells	8

Gut Microbiota as Predictive Biomarker for Chronic Heart Failure in Patients with Different Nutritional Risk	8
CRISPR-Cas9 Targeting PCSK9: A Promising Therapeutic Approach for Atherosclerosis	8
Correlation Between NLR to Albumin Ratio and 90-day Prognosis After Treatment for Acute Ischemic Stroke	8
ALDH2/eIF3E as Novel Regulators of Cardiac Ferroptosis	8
Normoxemic Extracorporeal Membrane Oxygenation Reduces Infarct Size and Preserves Mitochondrial Integrity in Preclinical Models of Acute Myocardial Infarction	7
Chronic Oxidative Stress as a Marker of Long-term Radiation-Induced Cardiovascular Outcomes in Breast Cancer	7
Cardiac Magnetic Resonance-Derived Left Ventricular Mechanical Dispersion Improves Risk Stratification of Hypertrophic Cardiomyopathy and its Correlations with Scar Heterogeneity	7
Inhibition of Hsp90 K284 Acetylation Aalleviates Cardiac Injury After Ischemia–Reperfusion Injury	7
Optimization of Strategy for Modified mRNA Inducing Cardiac-Specific Expression in Mice	7
Exploration of the Potential Biomarker FNDC5 for Discriminating Heart Failure in Patients with Coronary Atherosclerosis	7
p16INK4a Aggravated Sepsis-associated Cardiac Injury by Inhibiting the PI3K/AKT Pathway and Inducing Redox Imbalance	7
The Role of Gut Microbiota and Trimethylamine N-oxide in Cardiovascular Diseases	7
CD4+ Treg: A Novel Player in Cardiac Regenerative Therapy	7
TAVI Under Pressure: Intra-balloon Pressure Profiles During Balloon-Expandable TAVR—First Data from a Feasibility Study	7
Connecting the Dots: Stress Granule and Cardiovascular Diseases	7
Intravascular Ultrasound-Based Fractional Flow Reserve for Predicting Prognosis after Percutaneous Coronary Intervention	7
Automated Data Transformation and Feature Extraction for Oxygenation-Sensitive Cardiovascular Magnetic Resonance Images	7
Harnessing Electronic Medical Records in Cardiovascular Clinical Practice and Research	7
Emerging Paradigms in Atherosclerosis: The Impact of LncRNA PSMB8-AS1 on Vascular Inflammation and Plaque Formation	7
Identification of Gravida Serum Biomarkers for Noninvasive Prenatal Diagnosis Fetal Congenital Heart Disease	7
Postconditioning with Lactate-Enriched Blood for Reducing Lethal Reperfusion Injury in Humans	7
CNDP2: An Enzyme Linking Metabolism and Cardiovascular Diseases?	7
Correction to: LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide	7
Cardiac Metabolism, Reprogramming, and Diseases	7
Targeting Vascular Smooth Muscle Cell Senescence: A Novel Strategy for Vascular Diseases	7
Association Between Automated 3D Measurement of Coronary Luminal Narrowing and Risk of Future Myocardial Infarction	7
Plasma Biomarker Screening Based on Proteomic Signature of Patients with Resistant Hypertension	7
Past Trends and Future Directions of Cardiac Regenerative Medicine – A Systematic Analysis of Clinical Trial Registries	7
Non-Coding RNA-Mediated Gene Regulation in Cardiovascular Disorders: Current Insights and Future Directions	7
T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease	6
The Role of Testosterone in Atherosclerosis: View From Cell Cultures and Animal Models	6
The Fibrinogen-to-Albumin Ratio Is Associated with Poor Prognosis in Patients with Coronary Artery Disease: Findings from a Large Cohort	6
The Role of Regulatory T Cells in Heart Repair After Myocardial Infarction	6
Metabolomic Profiling for Predicting Coronary Artery Aneurysms and IVIG Resistance in Kawasaki Disease- An Exploratory Study	6
New Insights into the Genetics of Cardiomyopathies	6
Long-Term Training Increases Atrial Fibrillation Sustainability in Standardbred Racehorses	6
LncRNA SMILR Serves a Diagnostic Biomarker in Patients with Chronic Heart Failure and Regulates Functions of Vascular Endothelial Cells	6
Exploratory Study of the Effects of Irreversible Electroporation on Atherosclerotic Plaque in a Rabbit Model	6
Xanthatin Attenuates Angiotensin II-Induced Cardiac Hypertrophy by Targeting CREB5	6
Exosomal miRNAs: A New Frontier in Cardiovascular Disease Diagnosis and Treatment	6
The Effect of Extracellular Vesicles on Thrombosis	6
CXCR6 Mediates Pressure Overload-Induced Aortic Stiffness by Increasing Macrophage Recruitment and Reducing Exosome-miRNA29b	6
Hif-1α/Slit2 Mediates Vascular Smooth Muscle Cell Phenotypic Changes in Restenosis of Bypass Grafts	6
Heart Failure with Preserved Ejection Fraction: Pathogenesis, Diagnosis, Exercise, and Medical Therapies	6
Senescence-related Genes as Prognostic Markers for STEMI Patients: LASSO Regression-Based Bioinformatics and External Validation	6
Molecular Pathways of Endothelial Dysfunction Induced by Chronic Social Stress and Therapeutic Interventions	6
Percutaneous Alginate Hydrogel Endomyocardial Injection with a Novel Dedicated Catheter Delivery System: An Animal Feasibility Study	6
Past, Present and Future of Regenerative Gene Therapy for Ischemic Heart Failure	6
HNMT: A Key Pro-hypertrophic Factor in Pressure Overload	6
Silent Myocardial Infarction Revisited: Immuno-metabolic Mechanisms, Multimodal Biomarkers, and Translational Diagnostics	6
Knockdown of Mmu-circ-0001380 Attenuates Myocardial Ischemia/Reperfusion Injury via Modulating miR-106b-5p/Phlpp2 Axis	6
Predictors of Myocardial Ischemia in Patients with Kawasaki Disease: Insights from Patient-Specific Simulations of Coronary Hemodynamics	6
Comment on “A Potential Ratio for Detecting Subclinical Atherosclerosis: Insight into Advanced NMR Lipid Profiles in Severe Obesity”	6