OOIR: Observatory of International Research

Papers

(The median citation count of Tissue Engineering Part A is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Toward the Development of a Tissue Engineered Gradient Utilizing CRISPR-Guided Gene Modulation	94
TERMIS 2023 – European Chapter Manchester Central Conference Centre Manchester, UK March 28–31, 2023	62
Effect of Microbial Stimuli and Bone Morphogenetic Protein 2 on Ectopic Bone Formation	39
Optimized Biomanufacturing for Treatment of Volumetric Muscle Loss Enables Physiomimetic Recovery	37
Bioprinting of a Liposomal Oxygen-Releasing Scaffold for Ovary Tissue Engineering	37
Human Induced Pluripotent Stem Cell Encapsulation Geometry Impacts Three-Dimensional Developing Human Engineered Cardiac Tissue Functionality	36
Cardiovascular Tissue Engineering and Regeneration: A Plead for Further Knowledge Convergence	27
TGFβ-1 and Healing of Bone Defects in Large Animal and Rabbit Models: A Systematic Review	25
Impact of Cell Seeding Density and Cell Confluence on Human Tissue Engineered Skeletal Muscle	24
Abstracts TERMIS EU Freiburg, Germany May 20–23, 2025	23
Fast-Degrading Tissue-Engineered Vascular Grafts Lead to Increased Extracellular Matrix Cross-Linking Enzyme Expression	22
Call for Papers: Special Issue on Machine Learning in Tissue Engineering	21
Hematoxylin and Eosin Architecture Uncovers Clinically Divergent Niches in Pancreatic Cancer	21
Triply Periodic Minimal Surface-Based Scaffolds for Bone Tissue Engineering: A Mechanical, In Vitro and In Vivo Study	21
Stem Cell-Derived Insulin-Producing Cells in 3D Engineered Tissue in a Perfusion Flow Bioreactor	20
Tissue-Engineered Hepatocyte Sheets Supplemented with Adipose-Derived Stem Cells	20
Collagen Vitrigel Membrane-Coated Nylon Line Prevents Stenosis After Conization of the Cervix Uteri	19
Experiment-Based Validation of Corneal Lenticule Banking in a Health Authority-Licensed Facility	18
The Effects of Negative Pressure Therapy on Hair Growth of Mouse Models	18
Highly Porous Gas-Blown Hydrogels for Direct Cell Encapsulation with High Cell Viability	18
Increasing Collagen to Bioink Drives Mesenchymal Stromal Cells-Chondrogenesis from Hyaline to Calcified Layers	18
A Multilayer Nanofibrous Mat for the Topical Chemotherapy of the Positive Margin in Bladder Cancer	17
Improved Mesenchymal Stem Cell Viability in High-Stiffness, Translational Cartilage Matrix Hydrogels	16
Negative Printing for the Reinforcement of In Situ Tissue-Engineered Cartilage	16
Programming the Self-Organization of Endothelial Cells into Perfusable Microvasculature	16

Editorial for Special Issue on Artificial Intelligence in Tissue Engineering and Biology	15
Tricultured Cell Sheets Develop into Functional Pancreatic Islet Tissue with a Vascular Network	15
Rosalind Franklin Society Proudly Announces the 2022 Award Recipient for Tissue Engineering Part A	14
Acknowledgment of Reviewers 2024	14
Transcriptomic Regulation of Macrophages by Matrix-Bound Nanovesicle-Associated Interleukin-33	14
Restoration of Pregnancy Function Using a GT/PCL Biofilm in a Rabbit Model of Uterine Injury	14
Transcriptomics Demonstrates Significant Biological Effect of Growing Stem Cells on RGD-Cotton Scaffold	14
Smart Design for Hybrid Bioprinting of Scalable and Viable Tissue Constructs	13
Perspectives on Recent Developments and Directions in Tissue Engineering and Regenerative Medicine	13
The Role of Matrix Stiffness and Viscosity on Lipid Phenotype and Fat Lineage Potential	13
Effect of Chitosan on Synovial Membrane Derived Cells and Anterior Cruciate Ligament Fibroblasts	13
Regenerative Potential of Human Umbilical Cord Vein for Urethral Reconstruction in Male Rabbit Model	13
Enzyme-Mediated Nerve Growth Factor Release from Nanofibers Using Gelatin Microspheres	13
Silk Fibroin-Laponite Porous Microspheres as Cell Microcarriers for Osteogenic Differentiation	12
Enhancing Bone Healing Through Localized Cold Therapy in a Murine Femoral Fracture Model	12
Characterization of the Temporomandibular Joint Disc Complex in the Yucatan Minipig	12
Production of a Bioink Containing Decellularized Spinal Cord Tissue for 3D Bioprinting	12
Spatial Heterogeneity of Invading Glioblastoma Cells Regulated by Paracrine Factors	12
Call for Papers: Special Issue on Modulation of the Immune System to Improve Tissue Regeneration Strategies	11
Deep Learning Augmented Osteoarthritis Grading Standardization	11
Small-Caliber Vascular Grafts Engineered from Decellularized Leaves and Cross-Linked Gelatin	11
Targeted Activation of G-Protein Coupled Receptor-Mediated Ca²⁺ Signaling Drives Enhanced Cartilage-Like Matrix Formation	11
A Quick and Efficient Method for the Generation of Immunomodulatory Mesenchymal Stromal Cell from Human Induced Pluripotent Stem Cell	11
Dual Delivery of BMP2 and IGF1 Through Injectable Hydrogel Promotes Cranial Bone Defect Healing	11
Endochondral Bone Tissue Engineering Using Human Induced Pluripotent Stem Cells	11
Self-Assembly of Tooth Root Organoid from Postnatal Human Dental Stem Cells	10
Assessing Efficacy of Afatinib toward Elastic Matrix Repair in Aortic Aneurysms	10
Donor Age and Time in Culture Affect Dermal Fibroblast Contraction in an In Vitro Hydrogel Model	10
Repairing Volumetric Muscle Loss with Commercially Available Hydrogels in an Ovine Model	10
Prediction of the Effect of the Osteoarthritic Joint Microenvironment on Cartilage Repair	10
Evaluation of Dexamethasone-Eluting Cell-Seeded Constructs in a Preclinical Canine Model of Cartilage Repair	9
Scaffold Pore Geometry Guides Gene Regulation and Bone-like Tissue Formation in Dynamic Cultures	9
Program and Abstracts	9
Antithrombotic Revascularization Strategy of Bioengineered Liver Using a Biomimetic Polymer	9
Sodium Nitroprusside Stimulation of Elastic Matrix Regeneration by Aneurysmal Smooth Muscle Cells	9
A Hybrid Electrospun-Extruded Polydioxanone Suture for Tendon Tissue Regeneration	9
Inductive Remodeling of Extracellular Matrix Scaffolds in the Temporomandibular Joint of Pigs	9
Composite Spheroid-Laden Bilayer Hydrogel for Engineering Three-Dimensional Osteochondral Tissue	8
Posttranscriptional Modification to Modulate Progenitor Differentiation on Heterotypic Spheroids	8
Impact of Human Epidermal Growth Factor on Tissue-Engineered Skeletal Muscle Structure and Function	8
Engineered Tissue Graft for Repair of Injured Infraspinatus Rotator Cuff Tendon	8
30 Years of Tissue Engineering	8
Macrophages at Low-Inflammatory Status Improved Osteogenesis via Autophagy Regulation	8
TERMIS ‐ AMERICAS Toronto, Ontario, Canada July 10–13, 2022	8
Mesenchymal Stem Cell Sheets for Engineering of the Tendon–Bone Interface	8
Artificial Trachea from Microtissue Engineering and Three-Dimensional Printing for Tracheal Personalized Repair	8
Polycaprolactone/β-Tricalcium Phosphate Composite Scaffolds with Advanced Pore Geometries Promote Human Mesenchymal Stromal Cells’ Osteogenic Differentiation	8
Chondrogenesis of Mesenchymal Stem Cells through Local Release of TGF-β3 from Heparinized Collagen Biofabric	8
Mechanical Stimulation Induces Vasa Vasorum Capillary Alignment in a Fibrin-Based Tunica Adventitia	8
Regeneration of Functional Bladder Using Cell-seeded Amnion and P(LA/CL) Scaffolds	7

Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Tissue Engineering Part A	7
JNK2Gene Silencing for Elastic Matrix Regenerative Repair	7
LATS1/YAP1 Axis Controls Bone Regeneration on Distraction Osteogenesis by Activating Wnt/β-Catenin	7
Interspecies Comparison of Multilayer Mechanical Properties of Synovium Using Atomic Force Microscopy	7
Poly (ɛ-Caprolactone-co-l,l-Lactide) Vascular External Sheath Carrying Prednisone for Improving Patency Rate of the Vein Graft	7
Association with Cationized Gelatin Nanospheres Enhances Mitochondria Uptake and Membrane Potential	7
Call for Special Issue Papers: Special Issue for Prof. James Kirkpatrick in Honor of His Achievements in Tissue Engineering/Regenerative Medicine	7
Bile Duct Regeneration with an Artificial Bile Duct Made of Gelatin Hydrogel Nonwoven Fabrics	7
Oxidized Low-Density Lipoprotein Decreases the Survival of Bone Marrow Stem Cells via Inhibition of Bcl-2 Expression	7
Scaffold-Free Cartilage Construct from Infrapatellar Fat Pad Stem Cells for Cartilage Restoration	7
Glycations on Decellularized Muscle Matrix Reduce Muscle Regeneration and Increase Inflammation	7
Correction to: Wharton's Jelly-Mesenchymal Stem Cell-Engineered Conduit for Pediatric Translation in Heart Defect, by Iacobazzi, et al. Tissue Engineering Part A 2021;27(3-4):201–213; doi: 10.1	7
Development of a Self-Assembled Dermal Substitute from Human Fibroblasts Using Long-term Three-Dimensional Culture	7
Promoting a Cobalt Complex of Qingzhuan Dark Tea Polysaccharides on Fracture Healing in Rats	7
Intracellular Calcium and Sodium Modulation of Self-Assembled Neocartilage Using Costal Chondrocytes	7
Physiologic Doses of Transforming Growth Factor-β Improve the Composition of Engineered Articular Cartilage	7
Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease	6
A Ready-to-Use Purified Exosome Product for Volumetric Muscle Loss and Functional Recovery	6
Biogelx-IKVAV Is An Innovative Human Platelet Lysate-Adipose-Derived Stem Cells Delivery Strategy to Improve Peripheral Nerve Repair	6
Tensile Loaded Tissue-Engineered Human Tendon Constructs Stimulate Myotube Formation	6
Cryopreservation Alters Tissue Structure and Improves Differentiation of Engineered Skeletal Muscle	6
Immunomodulatory Strategies for Cartilage Regeneration in Osteoarthritis	6
The Effect of Dosing of Stromal Cell-Derived Factor 1 on Anal Sphincter Regeneration	6
Decellularization of Massive Bone Allografts By Perfusion: A New Protocol for Tissue Engineering	6
Downregulation of p38 MAPK Signaling Pathway Ameliorates Tissue-Engineered Corneal Epithelium	6
Profiles of Exosomal microRNAs in Joint Cells and Candidate microRNAs for Cartilage Regeneration	6
In Vivo Efficacy of a Novel, Sutureless Coaptation Device for Repairing Peripheral Nerve Defects	6
Schwann Cells Do Not Promote Myogenic Differentiation in the EPI Loop Model	6
Cyclic Tensile Stress Induces Skeletal Muscle Hypertrophy and Myonuclear Accretion in a 3D Model	6
Abstract Author Index by abstract number	6
Effects of Release of TSG-6 from Heparin Hydrogels on Supraspinatus Muscle Regeneration	6
The Inhibitory Effect of RADKPS on Pyroptosis of Nucleus Pulposus-Derived Mesenchymal Stem Cells	6
Designing Biomimetic 3D-Printed Osteochondral Scaffolds for Enhanced Load-Bearing Capacity	6
Spontaneous Alignment of Myotubes Through Myogenic Progenitor Cell Migration	6
Abstracts TERMIS EU Freiburg, Germany May 20–23, 2025	6
Ultrasound-Targeted Microbubble Destruction Assisted Delivery of Platelet-Rich Plasma-Derived Exosomes Promoting Peripheral Nerve Regeneration	5
Continuous Low-Intensity Ultrasound Improves Cartilage Repair in Rabbit Model of Subchondral Injury	5
Abstracts TERMIS EU Freiburg, Germany May 20–23, 2025	5
Effect of Eucomis autumnalis on the Osteogenic Differentiation of Adipose-Derived Stem Cells	5
Call for Special Issue Papers: Bioprinting	5
Erythrocyte Membrane Coating Alleviate Immune Response and Promoted Adipogenesis in Adipose Matrix	5
Amino Acid Uptake Limitations during Human Mesenchymal Stem Cell-Based Chondrogenesis	5
Aging Impairs Implant Osseointegration Through a Novel Reactive Oxygen Species-Hypoxia-Inducible Factor 1α/p53 Axis	5
Applications of Regenerative Tissue-Engineered Scaffolds for Treatment of Spinal Cord Injury	5
Editorial: Modulation of the Immune System to Improve Tissue Regeneration Strategies	5
The Effect of Low-Intensity Pulsed Ultrasound on Temporomandibular Joint Arthritis in Juvenile Rats	5
Effect of Cell Density of a Methacrylic Acid-Based Hydrogel Implant on Embedded Islet Function and Viability	5
Macromolecular Crowding Enhances Matrix Protein Deposition in Tissue-Engineered Vascular Grafts	5
In Vivo Delivery of M0, M1, and M2 Macrophage Subtypes via Genipin-Cross-Linked Collagen Biotextile	5
Porcine Acellular Nerve-Derived Hydrogel Improves Outcomes of Direct Muscle Neurotization in Rats	5
ZC3H13 Regulates Ferroptosis to Enhance Osteogenic Differentiation in Osteoporotic BMSCs	4
Cyclic Stretching Enhances Angiocrine Signals at Liver Bud Stage from Human Pluripotent Stem Cells in Two-Dimensional Culture	4
Induction of Cartilage Regeneration by Nanoparticles Loaded with Dentin Matrix Extracted Proteins	4
Bioprinting: Mechanical Stabilization and Reinforcement Strategies in Regenerative Medicine	4
Stem Cell-Seeded 3D-Printed Scaffolds Combined with Self-Assembling Peptides for Bone Defect Repair	4
Metformin Treatment of Macrophages Increases Microvessel Growth in Three-Dimensional Hydrogel Coculture	4
Differentiating Engineered Tissue Images and Experimental Factors to Classify Cardiomyocyte Content	4
Abstract Author Indexby abstract number	4
Editorial for Special Issue on Machine Learning in Tissue Engineering	4
Three-Dimensional Bioprinting of Organoids: Past, Present, and Prospective	4
Abstract Author Index by abstract number	4
Exosome Cell Origin Affects In Vitro Markers of Tendon Repair in Ovine Macrophages and Tenocytes	4
A Standardized g-Force Allows the Preparation of Similar Platelet-Rich Fibrin Qualities Regardless of Rotor Angle	4
A Novel Injectable Cell-Loaded Hydrogel System for Cartilage Repair: In Vivo and In Vitro Study	4
Abstract Author Indexby abstract number	4
Regenerative Potential of Bone Morphogenetic Protein 7-Engineered Mesenchymal Stem Cells in Ligature-Induced Periodontitis	4
Revealing Early Spatial Patterns of Cellular Responsivity in Fiber-Reinforced Microenvironments	4
Subcutaneously Transplanted Fresh Cartilage in Allogeneic and Xenogeneic Immunocompetent Mouse	3
Combining a Vascular Bundle and 3D Printed Scaffold with BMP-2 Improves Bone Repair and Angiogenesis	3
Osteoblast-Mesenchymal Stem Cell Coculture Drives In Vitro Osteogenesis in 3D Bioprinted Periosteum	3
Aligned Gelatin Microribbon Scaffolds with Hydroxyapatite Gradient for Engineering the Bone–Tendon Interface	3
Three-Dimensional Culture Promotes Secretion of Extracellular Matrix Structure Fat Flap with Lipoaspirates in Vitro	3
Liquid Ventilation Reconditions Isolated Rat Lungs Following Ischemia–Reperfusion Injury	3
Acknowledgment of Reviewers 2021	3
Development of a Three-Dimensional Bioartificial Shoulder Joint Implant Mimetic of Periprosthetic Joint Infection	3
E2-Loaded Microcapsules and Bone Marrow–Derived Mesenchymal Stem Cells with Injectable Scaffolds for Endometrial Regeneration Application	3
Dental Pulp Cell Sheets Enhance Facial Nerve Regeneration via Local Neurotrophic Factor Delivery	3
Dual Role of Ibuprofen and Indomethacin in Promoting Peripheral Nerve Regeneration In Vitro	3
Abstract Author Indexby abstract number	3
Tissues with Patterned Vessels or Protein Release Induce Vascular Chemotaxis in an In Vitro Platform	3

Quality Assessment by Bile Composition in Normothermic Machine Perfusion of Rat Livers	3
7^th TERMIS World Congress Seattle, Washington June 25–28, 2024	3
Advancing Perfusion Models: Dual-Vessel Ex Vivo Rat Liver Perfusion Based on a Clinical Setup	3
Selection of Force Sensors for In Situ Measurement of Neotissue Microenvironments	3
Repair of Osteochondral Defect with Acellular Cartilage Matrix and Thermosensitive Hydrogel Scaffold	3
A Chondrosphere-Based Scaffold Free Approach to Manufacture anIn VitroArticular Cartilage Model	3
The UCMSC-bFGF/Scaffold System Accelerates the Healing of the Uterine Full-Thickness Injury	3
Hepatocytes and Endothelial Networks in a Fluid-Based In Vitro Model of Liver Drug Metabolism	3
Differentiated and Untreated Juvenile Chondrocyte Sheets Regenerate Cartilage Similarly In Vivo	3
Cell Therapy by Mesenchymal Stromal Cells Versus Myoblasts in a Pig Model of Urinary Incontinence	3
Surface Engineering for Dental Implantology: Favoring Tissue Responses Along the Implant	2
3D Printed Platelet-Rich Plasma-Loaded Scaffold with Sustained Cytokine Release for Bone Defect Repair	2
Three-Dimensional Printed Design of Antibiotic-Releasing Esophageal Patches for Antimicrobial Activity Prevention	2
Progenitor Cell Sources for 3D Bioprinting of Lymphatic Vessels and Potential Clinical Application	2
Biodegradable PHBVHHx-PEG/Collagen Hydrogel Scaffolds for Cartilage Repair	2
Generation of Pigmented Skin Grafts from Human Hair Follicles and Dermal Fibroblasts	2
Reconstruction of Fibrocartilage with Fibrous Alignment of Type I Collagen in Scaffold-Free Manner	2
Vascularization of Human Acellular Dermal Matrices: A Comparative Study in a Nonhuman Primate Model	2
Macrophage Mechano-Responsiveness Within Three-Dimensional Tissue Matrix upon Mechanotherapy-Associated Strains	2
Depletion of MicroRNA-100-5p Promotes Osteogenesis Via Lysine(K)-Specific Demethylase 6B	2
Autologous Bilayered Adipose-Derived Mesenchymal Cell-Gelatin Sheets Reconstruct Ureters in Rabbits	2
Limited Expansion of Human Hepatocytes in FAH/RAG2-Deficient Swine	2
Matrix Composition Modulates Vitamin D3's Effects on 3D Collagen Fiber Organization by MCF10A Cells	2
Extracellular Matrix Alignment Directs Provisional Matrix Assembly and Three Dimensional Fibrous Tissue Closure	2
Inhibitory Effects of Combined Bone Morphogenetic Protein 2, Vascular Endothelial Growth Factor, and Basic Fibroblast Growth Factor on Osteoclast Differentiation and Activity	2
Epigenetic Priming Enhances Chondrogenic Potential of Expanded Chondrocytes	2
Characterization of Native Extracellular Matrix of Patient-Derived Glioblastoma Multiforme Organoids	2
Implantation of Human-Induced Pluripotent Stem Cell-Derived Cartilage in Bone Defects of Mice	2
The Jagged-1/Notch1 Signaling Pathway Promotes the Construction of Tissue-Engineered Heart Valves	2
Extracellular Matrix Hydrogels Promote Expression of Muscle-Tendon Junction Proteins	2
Thirtieth Anniversary of Tissue Engineering: A Congratulations and a Few Thoughts	2
Magnetic and Biocompatible Polyurethane Nanofiber Biomaterial for Tissue Engineering	2
Acknowledgment of Reviewers 2022	2
From Promise to Practice: Recent Growth in 30 Years of Tissue Engineering Commercialization	2
Supercritical Carbon Dioxide Decellularization of Porcine Nerve Matrix for Regenerative Medicine	2
An Improved Diagnostic Tool to Predict Cartilage Formation in an Osteoarthritic Joint Environment	2
Fast Degradable Calcium Phosphate Cement for Maxillofacial Bone Regeneration	2
TERMIS 2023 – European Chapter Manchester Central Conference Centre Manchester, UK March 28–31, 2023	2
Thirty Years of Tissue Engineering	2
Mapping Biomaterial Complexity by Machine Learning	2
Aspects of a Suspended Bioprinting System Affect Cell Viability and Support Bath Properties	2
Call for Papers: Special Issue on Modulation of the Immune System to Improve Tissue Regeneration Strategies	2
Osteoclast Incorporation in an In Vitro 3D Model of Endochondral Ossification	2
Bone Marrow Mobilization and Local Stromal Cell-Derived Factor-1α Delivery Enhances Nascent Supraspinatus Muscle Fiber Growth	2
Organotypic 3D Cellular Models Mimicking the Epithelio-Ectomesenchymal Bilayer During Odontogenesis	2
In Vivo Engineering and Transplantation of Axially Vascularized and Epithelialized Flaps in Rats	2
Abstract Author Index by abstract number	2
Three-Dimensional Cell Printed Lock-Key Structure for Oral Soft and Hard Tissue Regeneration	2
Alginate-Based Bioinks for 3D Bioprinting and Fabrication of Anatomically Accurate Bone Grafts	2
Call for Special Issue Papers: Artificial Intelligence in Tissue Engineering and Biology	2
Acrylated Hyaluronic-Acid Based Hydrogel for the Treatment of Craniofacial Volumetric Muscle Loss	2
¹³C Metabolic Flux Analysis in Chondrocytes Reveals a Novel Switch in Metabolic Phenotype	2
Cell-Derived Extracellular Matrix Fiber Scaffolds Improve Recovery from Volumetric Muscle Loss	2