OOIR: Observatory of International Research

Papers

(The median citation count of Tissue Engineering Part A is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Bioprinting of a Liposomal Oxygen-Releasing Scaffold for Ovary Tissue Engineering	43
Cardiovascular Tissue Engineering and Regeneration: A Plead for Further Knowledge Convergence	39
Effect of Microbial Stimuli and Bone Morphogenetic Protein 2 on Ectopic Bone Formation	38
TERMIS 2023 – European Chapter Manchester Central Conference Centre Manchester, UK March 28–31, 2023	36
Toward the Development of a Tissue Engineered Gradient Utilizing CRISPR-Guided Gene Modulation	29
Optimized Biomanufacturing for Treatment of Volumetric Muscle Loss Enables Physiomimetic Recovery	25
Human Induced Pluripotent Stem Cell Encapsulation Geometry Impacts Three-Dimensional Developing Human Engineered Cardiac Tissue Functionality	24
Fast-Degrading Tissue-Engineered Vascular Grafts Lead to Increased Extracellular Matrix Cross-Linking Enzyme Expression	23
Hematoxylin and Eosin Architecture Uncovers Clinically Divergent Niches in Pancreatic Cancer	21
Impact of Cell Seeding Density and Cell Confluence on Human Tissue Engineered Skeletal Muscle	21
Abstracts TERMIS EU Freiburg, Germany May 20–23, 2025	21
TGFβ-1 and Healing of Bone Defects in Large Animal and Rabbit Models: A Systematic Review	21
Call for Papers: Special Issue on Machine Learning in Tissue Engineering	20
Triply Periodic Minimal Surface-Based Scaffolds for Bone Tissue Engineering: A Mechanical, In Vitro and In Vivo Study	20
Tissue-Engineered Hepatocyte Sheets Supplemented with Adipose-Derived Stem Cells	19
Increasing Collagen to Bioink Drives Mesenchymal Stromal Cells-Chondrogenesis from Hyaline to Calcified Layers	18
Collagen Vitrigel Membrane-Coated Nylon Line Prevents Stenosis After Conization of the Cervix Uteri	18
Programming the Self-Organization of Endothelial Cells into Perfusable Microvasculature	16
Highly Porous Gas-Blown Hydrogels for Direct Cell Encapsulation with High Cell Viability	16
The Effects of Negative Pressure Therapy on Hair Growth of Mouse Models	16
Improved Mesenchymal Stem Cell Viability in High-Stiffness, Translational Cartilage Matrix Hydrogels	15
A Multilayer Nanofibrous Mat for the Topical Chemotherapy of the Positive Margin in Bladder Cancer	15
Negative Printing for the Reinforcement of In Situ Tissue-Engineered Cartilage	15
Tricultured Cell Sheets Develop into Functional Pancreatic Islet Tissue with a Vascular Network	14
Transcriptomics Demonstrates Significant Biological Effect of Growing Stem Cells on RGD-Cotton Scaffold	14

Acknowledgment of Reviewers 2024	14
Experiment-Based Validation of Corneal Lenticule Banking in a Health Authority-Licensed Facility	14
Restoration of Pregnancy Function Using a GT/PCL Biofilm in a Rabbit Model of Uterine Injury	14
Editorial for Special Issue on Artificial Intelligence in Tissue Engineering and Biology	13
Production of a Bioink Containing Decellularized Spinal Cord Tissue for 3D Bioprinting	13
Rosalind Franklin Society Proudly Announces the 2022 Award Recipient for Tissue Engineering Part A	13
Silk Fibroin-Laponite Porous Microspheres as Cell Microcarriers for Osteogenic Differentiation	13
Effect of Chitosan on Synovial Membrane Derived Cells and Anterior Cruciate Ligament Fibroblasts	13
Regenerative Potential of Human Umbilical Cord Vein for Urethral Reconstruction in Male Rabbit Model	13
Enhancing Bone Healing Through Localized Cold Therapy in a Murine Femoral Fracture Model	13
Perspectives on Recent Developments and Directions in Tissue Engineering and Regenerative Medicine	13
Transcriptomic Regulation of Macrophages by Matrix-Bound Nanovesicle-Associated Interleukin-33	12
Characterization of the Temporomandibular Joint Disc Complex in the Yucatan Minipig	12
Deep Learning Augmented Osteoarthritis Grading Standardization	12
Targeted Activation of G-Protein Coupled Receptor-Mediated Ca²⁺ Signaling Drives Enhanced Cartilage-Like Matrix Formation	12
The Role of Matrix Stiffness and Viscosity on Lipid Phenotype and Fat Lineage Potential	12
Dual Delivery of BMP2 and IGF1 Through Injectable Hydrogel Promotes Cranial Bone Defect Healing	11
Spatial Heterogeneity of Invading Glioblastoma Cells Regulated by Paracrine Factors	11
Smart Design for Hybrid Bioprinting of Scalable and Viable Tissue Constructs	11
Enzyme-Mediated Nerve Growth Factor Release from Nanofibers Using Gelatin Microspheres	11
Assessing Efficacy of Afatinib toward Elastic Matrix Repair in Aortic Aneurysms	10
Prediction of the Effect of the Osteoarthritic Joint Microenvironment on Cartilage Repair	10
Endochondral Bone Tissue Engineering Using Human Induced Pluripotent Stem Cells	10
A Quick and Efficient Method for the Generation of Immunomodulatory Mesenchymal Stromal Cell from Human Induced Pluripotent Stem Cell	10
Repairing Volumetric Muscle Loss with Commercially Available Hydrogels in an Ovine Model	10
Call for Papers: Special Issue on Modulation of the Immune System to Improve Tissue Regeneration Strategies	10
Antithrombotic Revascularization Strategy of Bioengineered Liver Using a Biomimetic Polymer	9
A Hybrid Electrospun-Extruded Polydioxanone Suture for Tendon Tissue Regeneration	9
Sodium Nitroprusside Stimulation of Elastic Matrix Regeneration by Aneurysmal Smooth Muscle Cells	9
Evaluation of Dexamethasone-Eluting Cell-Seeded Constructs in a Preclinical Canine Model of Cartilage Repair	9
Donor Age and Time in Culture Affect Dermal Fibroblast Contraction in an In Vitro Hydrogel Model	9
Inductive Remodeling of Extracellular Matrix Scaffolds in the Temporomandibular Joint of Pigs	9
Program and Abstracts	9
Composite Spheroid-Laden Bilayer Hydrogel for Engineering Three-Dimensional Osteochondral Tissue	9
Small-Caliber Vascular Grafts Engineered from Decellularized Leaves and Cross-Linked Gelatin	9
Self-Assembly of Tooth Root Organoid from Postnatal Human Dental Stem Cells	9
Artificial Trachea from Microtissue Engineering and Three-Dimensional Printing for Tracheal Personalized Repair	9
30 Years of Tissue Engineering	9
Macrophages at Low-Inflammatory Status Improved Osteogenesis via Autophagy Regulation	8
TERMIS ‐ AMERICAS Toronto, Ontario, Canada July 10–13, 2022	8
Engineered Tissue Graft for Repair of Injured Infraspinatus Rotator Cuff Tendon	8
Mechanical Stimulation Induces Vasa Vasorum Capillary Alignment in a Fibrin-Based Tunica Adventitia	8
Mesenchymal Stem Cell Sheets for Engineering of the Tendon–Bone Interface	8
Posttranscriptional Modification to Modulate Progenitor Differentiation on Heterotypic Spheroids	8
Oxidized Low-Density Lipoprotein Decreases the Survival of Bone Marrow Stem Cells via Inhibition of Bcl-2 Expression	8
Promoting a Cobalt Complex of Qingzhuan Dark Tea Polysaccharides on Fracture Healing in Rats	8
Chondrogenesis of Mesenchymal Stem Cells through Local Release of TGF-β3 from Heparinized Collagen Biofabric	8
Polycaprolactone/β-Tricalcium Phosphate Composite Scaffolds with Advanced Pore Geometries Promote Human Mesenchymal Stromal Cells’ Osteogenic Differentiation	8
Bile Duct Regeneration with an Artificial Bile Duct Made of Gelatin Hydrogel Nonwoven Fabrics	8
Development of a Self-Assembled Dermal Substitute from Human Fibroblasts Using Long-term Three-Dimensional Culture	8

Abstract Author Index by abstract number	7
Regeneration of Functional Bladder Using Cell-seeded Amnion and P(LA/CL) Scaffolds	7
LATS1/YAP1 Axis Controls Bone Regeneration on Distraction Osteogenesis by Activating Wnt/β-Catenin	7
Scaffold-Free Cartilage Construct from Infrapatellar Fat Pad Stem Cells for Cartilage Restoration	7
Association with Cationized Gelatin Nanospheres Enhances Mitochondria Uptake and Membrane Potential	7
Correction to: Wharton's Jelly-Mesenchymal Stem Cell-Engineered Conduit for Pediatric Translation in Heart Defect, by Iacobazzi, et al. Tissue Engineering Part A 2021;27(3-4):201–213; doi: 10.1	7
Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Tissue Engineering Part A	7
Physiologic Doses of Transforming Growth Factor-β Improve the Composition of Engineered Articular Cartilage	7
Call for Special Issue Papers: Special Issue for Prof. James Kirkpatrick in Honor of His Achievements in Tissue Engineering/Regenerative Medicine	7
Glycations on Decellularized Muscle Matrix Reduce Muscle Regeneration and Increase Inflammation	7
Downregulation of p38 MAPK Signaling Pathway Ameliorates Tissue-Engineered Corneal Epithelium	7
Decellularization of Massive Bone Allografts By Perfusion: A New Protocol for Tissue Engineering	7
JNK2Gene Silencing for Elastic Matrix Regenerative Repair	7
Intracellular Calcium and Sodium Modulation of Self-Assembled Neocartilage Using Costal Chondrocytes	7
Poly (ɛ-Caprolactone-co-l,l-Lactide) Vascular External Sheath Carrying Prednisone for Improving Patency Rate of the Vein Graft	7
Interspecies Comparison of Multilayer Mechanical Properties of Synovium Using Atomic Force Microscopy	7
The Effect of Dosing of Stromal Cell-Derived Factor 1 on Anal Sphincter Regeneration	6
Abstracts TERMIS EU Freiburg, Germany May 20–23, 2025	6
Tensile Loaded Tissue-Engineered Human Tendon Constructs Stimulate Myotube Formation	6
In Vivo Efficacy of a Novel, Sutureless Coaptation Device for Repairing Peripheral Nerve Defects	6
Developing a Functional Osteoarthritis Model Using Human Osteochondral–Synovial Explants	6
Spontaneous Alignment of Myotubes Through Myogenic Progenitor Cell Migration	6
Cyclic Tensile Stress Induces Skeletal Muscle Hypertrophy and Myonuclear Accretion in a 3D Model	6
Cryopreservation Alters Tissue Structure and Improves Differentiation of Engineered Skeletal Muscle	6
Profiles of Exosomal microRNAs in Joint Cells and Candidate microRNAs for Cartilage Regeneration	6
Effects of Release of TSG-6 from Heparin Hydrogels on Supraspinatus Muscle Regeneration	6
Immunomodulatory Strategies for Cartilage Regeneration in Osteoarthritis	6
Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease	6
Amino Acid Uptake Limitations during Human Mesenchymal Stem Cell-Based Chondrogenesis	6
Designing Biomimetic 3D-Printed Osteochondral Scaffolds for Enhanced Load-Bearing Capacity	6
Schwann Cells Do Not Promote Myogenic Differentiation in the EPI Loop Model	6
Biogelx-IKVAV Is An Innovative Human Platelet Lysate-Adipose-Derived Stem Cells Delivery Strategy to Improve Peripheral Nerve Repair	6
A Ready-to-Use Purified Exosome Product for Volumetric Muscle Loss and Functional Recovery	6
Tissue-Engineered Endothelial Keratoplasty with Controlled Cell Density: Toward Super TEEKs	6
The Inhibitory Effect of RADKPS on Pyroptosis of Nucleus Pulposus-Derived Mesenchymal Stem Cells	6
Effect of Cell Density of a Methacrylic Acid-Based Hydrogel Implant on Embedded Islet Function and Viability	6
In Vivo Delivery of M0, M1, and M2 Macrophage Subtypes via Genipin-Cross-Linked Collagen Biotextile	5
The Effect of Low-Intensity Pulsed Ultrasound on Temporomandibular Joint Arthritis in Juvenile Rats	5
Applications of Regenerative Tissue-Engineered Scaffolds for Treatment of Spinal Cord Injury	5
Continuous Low-Intensity Ultrasound Improves Cartilage Repair in Rabbit Model of Subchondral Injury	5
Aging Impairs Implant Osseointegration Through a Novel Reactive Oxygen Species-Hypoxia-Inducible Factor 1α/p53 Axis	5
Editorial: Modulation of the Immune System to Improve Tissue Regeneration Strategies	5
Macromolecular Crowding Enhances Matrix Protein Deposition in Tissue-Engineered Vascular Grafts	5
Abstracts TERMIS EU Freiburg, Germany May 20–23, 2025	5
Call for Special Issue Papers: Bioprinting	5
Editorial for Special Issue on Machine Learning in Tissue Engineering	4
Revealing Early Spatial Patterns of Cellular Responsivity in Fiber-Reinforced Microenvironments	4
Induction of Cartilage Regeneration by Nanoparticles Loaded with Dentin Matrix Extracted Proteins	4
Differentiating Engineered Tissue Images and Experimental Factors to Classify Cardiomyocyte Content	4
Cyclic Stretching Enhances Angiocrine Signals at Liver Bud Stage from Human Pluripotent Stem Cells in Two-Dimensional Culture	4
Abstract Author Indexby abstract number	4
Bioprinting: Mechanical Stabilization and Reinforcement Strategies in Regenerative Medicine	4
Regenerative Potential of Bone Morphogenetic Protein 7-Engineered Mesenchymal Stem Cells in Ligature-Induced Periodontitis	4
A Novel Injectable Cell-Loaded Hydrogel System for Cartilage Repair: In Vivo and In Vitro Study	4
A Chondrosphere-Based Scaffold Free Approach to Manufacture anIn VitroArticular Cartilage Model	4
Effect of Eucomis autumnalis on the Osteogenic Differentiation of Adipose-Derived Stem Cells	4
Erythrocyte Membrane Coating Alleviate Immune Response and Promoted Adipogenesis in Adipose Matrix	4
A Standardized g-Force Allows the Preparation of Similar Platelet-Rich Fibrin Qualities Regardless of Rotor Angle	4
Exosome Cell Origin Affects In Vitro Markers of Tendon Repair in Ovine Macrophages and Tenocytes	4
ZC3H13 Regulates Ferroptosis to Enhance Osteogenic Differentiation in Osteoporotic BMSCs	4
Abstract Author Index by abstract number	4
Metformin Treatment of Macrophages Increases Microvessel Growth in Three-Dimensional Hydrogel Coculture	4
Porcine Acellular Nerve-Derived Hydrogel Improves Outcomes of Direct Muscle Neurotization in Rats	4
Ultrasound-Targeted Microbubble Destruction Assisted Delivery of Platelet-Rich Plasma-Derived Exosomes Promoting Peripheral Nerve Regeneration	4
Abstract Author Indexby abstract number	4
Stem Cell-Seeded 3D-Printed Scaffolds Combined with Self-Assembling Peptides for Bone Defect Repair	4
Three-Dimensional Bioprinting of Organoids: Past, Present, and Prospective	4
Abstract Author Indexby abstract number	3
Acknowledgment of Reviewers 2021	3
7^th TERMIS World Congress Seattle, Washington June 25–28, 2024	3
Magnetic and Biocompatible Polyurethane Nanofiber Biomaterial for Tissue Engineering	3
Extracellular Matrix Hydrogels Promote Expression of Muscle-Tendon Junction Proteins	3
Cell Therapy by Mesenchymal Stromal Cells Versus Myoblasts in a Pig Model of Urinary Incontinence	3
The UCMSC-bFGF/Scaffold System Accelerates the Healing of the Uterine Full-Thickness Injury	3
Quality Assessment by Bile Composition in Normothermic Machine Perfusion of Rat Livers	3
Osteoblast-Mesenchymal Stem Cell Coculture Drives In Vitro Osteogenesis in 3D Bioprinted Periosteum	3
Tissues with Patterned Vessels or Protein Release Induce Vascular Chemotaxis in an In Vitro Platform	3
Three-Dimensional Culture Promotes Secretion of Extracellular Matrix Structure Fat Flap with Lipoaspirates in Vitro	3
Acknowledgment of Reviewers 2022	3
E2-Loaded Microcapsules and Bone Marrow–Derived Mesenchymal Stem Cells with Injectable Scaffolds for Endometrial Regeneration Application	3

Advancing Perfusion Models: Dual-Vessel Ex Vivo Rat Liver Perfusion Based on a Clinical Setup	3
Subcutaneously Transplanted Fresh Cartilage in Allogeneic and Xenogeneic Immunocompetent Mouse	3
Selection of Force Sensors for In Situ Measurement of Neotissue Microenvironments	3
Liquid Ventilation Reconditions Isolated Rat Lungs Following Ischemia–Reperfusion Injury	3
Repair of Osteochondral Defect with Acellular Cartilage Matrix and Thermosensitive Hydrogel Scaffold	3
Aligned Gelatin Microribbon Scaffolds with Hydroxyapatite Gradient for Engineering the Bone–Tendon Interface	3
Three-Dimensional Cell Printed Lock-Key Structure for Oral Soft and Hard Tissue Regeneration	3
Reconstruction of Fibrocartilage with Fibrous Alignment of Type I Collagen in Scaffold-Free Manner	3
Biodegradable PHBVHHx-PEG/Collagen Hydrogel Scaffolds for Cartilage Repair	3
Development of a Three-Dimensional Bioartificial Shoulder Joint Implant Mimetic of Periprosthetic Joint Infection	3
Differentiated and Untreated Juvenile Chondrocyte Sheets Regenerate Cartilage Similarly In Vivo	3
Combining a Vascular Bundle and 3D Printed Scaffold with BMP-2 Improves Bone Repair and Angiogenesis	3
Dual Role of Ibuprofen and Indomethacin in Promoting Peripheral Nerve Regeneration In Vitro	3
Abstract Author Index by abstract number	2
Organotypic 3D Cellular Models Mimicking the Epithelio-Ectomesenchymal Bilayer During Odontogenesis	2
Depletion of MicroRNA-100-5p Promotes Osteogenesis Via Lysine(K)-Specific Demethylase 6B	2
The Jagged-1/Notch1 Signaling Pathway Promotes the Construction of Tissue-Engineered Heart Valves	2
In Vivo Differentiation of hESC-Derived Neural Crest Cells into Trabecular Meshwork Cells	2
TERMIS 2023 – European Chapter Manchester Central Conference Centre Manchester, UK March 28–31, 2023	2
Tissue Engineering and Regenerative Medicine International Society Asia‐Pacific Chapter Conference 2022	2
In Vivo Engineering and Transplantation of Axially Vascularized and Epithelialized Flaps in Rats	2
Limited Expansion of Human Hepatocytes in FAH/RAG2-Deficient Swine	2
Progenitor Cell Sources for 3D Bioprinting of Lymphatic Vessels and Potential Clinical Application	2
Call for Papers: Special Issue on Modulation of the Immune System to Improve Tissue Regeneration Strategies	2
Thirty Years of Tissue Engineering	2
Extracellular Matrix Alignment Directs Provisional Matrix Assembly and Three Dimensional Fibrous Tissue Closure	2
Cell-Derived Extracellular Matrix Fiber Scaffolds Improve Recovery from Volumetric Muscle Loss	2
Implantation of Human-Induced Pluripotent Stem Cell-Derived Cartilage in Bone Defects of Mice	2
Characterization of Native Extracellular Matrix of Patient-Derived Glioblastoma Multiforme Organoids	2
From Promise to Practice: Recent Growth in 30 Years of Tissue Engineering Commercialization	2
Contraction Control of Aligned Myofiber Sheet Tissue by Parallel Oriented Induced Pluripotent Stem Cell-Derived Neurons	2
Acrylated Hyaluronic-Acid Based Hydrogel for the Treatment of Craniofacial Volumetric Muscle Loss	2
An Improved Diagnostic Tool to Predict Cartilage Formation in an Osteoarthritic Joint Environment	2
3D Printed Platelet-Rich Plasma-Loaded Scaffold with Sustained Cytokine Release for Bone Defect Repair	2
¹³C Metabolic Flux Analysis in Chondrocytes Reveals a Novel Switch in Metabolic Phenotype	2
Mapping Biomaterial Complexity by Machine Learning	2
Inhibitory Effects of Combined Bone Morphogenetic Protein 2, Vascular Endothelial Growth Factor, and Basic Fibroblast Growth Factor on Osteoclast Differentiation and Activity	2
Surface Engineering for Dental Implantology: Favoring Tissue Responses Along the Implant	2
Three-Dimensional Printed Design of Antibiotic-Releasing Esophageal Patches for Antimicrobial Activity Prevention	2
Osteoclast Incorporation in an In Vitro 3D Model of Endochondral Ossification	2
Vascularization of Human Acellular Dermal Matrices: A Comparative Study in a Nonhuman Primate Model	2
Epigenetic Priming Enhances Chondrogenic Potential of Expanded Chondrocytes	2
Thirtieth Anniversary of Tissue Engineering: A Congratulations and a Few Thoughts	2
Generation of Pigmented Skin Grafts from Human Hair Follicles and Dermal Fibroblasts	2
Matrix Composition Modulates Vitamin D3's Effects on 3D Collagen Fiber Organization by MCF10A Cells	2
Fast Degradable Calcium Phosphate Cement for Maxillofacial Bone Regeneration	2
Supercritical Carbon Dioxide Decellularization of Porcine Nerve Matrix for Regenerative Medicine	2
Call for Special Issue Papers: Artificial Intelligence in Tissue Engineering and Biology	2
Macrophage Mechano-Responsiveness Within Three-Dimensional Tissue Matrix upon Mechanotherapy-Associated Strains	2
Bone Marrow Mobilization and Local Stromal Cell-Derived Factor-1α Delivery Enhances Nascent Supraspinatus Muscle Fiber Growth	2
Aspects of a Suspended Bioprinting System Affect Cell Viability and Support Bath Properties	2