Translational Oncology

Article	Citations
Global colorectal cancer burden in 2020 and projections to 2040	1207
Hypoxia, partial EMT and collective migration: Emerging culprits in metastasis	133
Early lung cancer diagnostic biomarker discovery by machine learning methods	130
NK cell infiltration is associated with improved overall survival in solid cancers: A systematic review and meta-analysis	114
Plasticity of cancer cell invasion: Patterns and mechanisms	109
3D Bioprinted cancer models: Revolutionizing personalized cancer therapy	109
The interaction mechanism between autophagy and apoptosis in colon cancer	86
Influence of cholesterol on cancer progression and therapy	79
The PI3K/Akt/mTOR pathway in lung cancer; oncogenic alterations, therapeutic opportunities, challenges, and a glance at the application of nanoparticles	72
HDAC inhibitors: Targets for tumor therapy, immune modulation and lung diseases	70
Extracellular heat shock proteins and cancer: New perspectives	67
The remodelling of actin composition as a hallmark of cancer	66
Chlorogenic acid: Potential source of natural drugs for the therapeutics of fibrosis and cancer	61
Therapeutic approaches for the treatment of head and neck squamous cell carcinoma–An update on clinical trials	56
Regulation of CD47 expression in cancer cells	56
Targeting cancer-cell mitochondria and metabolism to improve radiotherapy response	50
PLK1 inhibition-based combination therapies for cancer management	49
Etoposide, an anticancer drug involved in therapy-related secondary leukemia: Enzymes at play	46
Using deep learning to predict anti-PD-1 response in melanoma and lung cancer patients from histopathology images	45
Drug screening model meets cancer organoid technology	44
Recent advances in the field of single-cell proteomics	42
Narrative review of the influence of diabetes mellitus and hyperglycemia on colorectal cancer risk and oncological outcomes	41
Resistin: A journey from metabolism to cancer	41
Mesenchymal stem/stromal cells: Developmental origin, tumorigenesis and translational cancer therapeutics	39
The spontaneous remission of cancer: Current insights and therapeutic significance	39

Combination therapy: Future directions of immunotherapy in small cell lung cancer	38
Hypoxia-induced therapy resistance: Available hypoxia-targeting strategies and current advances in head and neck cancer	37
Improved survival in several cancers with use of H1-antihistamines desloratadine and loratadine	37
Three-dimensional organoid culture unveils resistance to clinical therapies in adult and pediatric glioblastoma	36
Iron (Fe)-doped mesoporous 45S5 bioactive glasses: Implications for cancer therapy	36
The current landscape of the FDA approved companion diagnostics	35
m6A demethylase FTO renders radioresistance of nasopharyngeal carcinoma via promoting OTUB1-mediated anti-ferroptosis	35
Long non-coding RNAs in cancer stem cells	34
Transition metal ion-doped ferrites nanoparticles for bioimaging and cancer therapy	34
Hsa_circ_0092276 promotes doxorubicin resistance in breast cancer cells by regulating autophagy via miR-348/ATG7 axis	34
Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer	33
Genomic identification of sarcoma radiosensitivity and the clinical implications for radiation dose personalization	33
Superoxide-mediated ferroptosis in human cancer cells induced by sodium selenite	33
The role of exosomal PD-L1 in tumor immunotherapy	32
Factors associated with and risk factors for depression in cancer patients – A systematic literature review	31
Novel antigens of CAR T cell therapy: New roads; old destination	31
The N6-methyladenosine reader protein YTHDC2 promotes gastric cancer progression via enhancing YAP mRNA translation	31
Loss of ATRX confers DNA repair defects and PARP inhibitor sensitivity	31
Natural flavonoids exhibit potent anticancer activity by targeting microRNAs in cancer: A signature step hinting towards clinical perfection	30
Anti-CTLA-4 and anti-PD-1 immunotherapies repress tumor progression in preclinical breast and colon model with independent regulatory T cells response	30
The approval and withdrawal of melphalan flufenamide (melflufen): Implications for the state of the FDA.	29
Clinical significance and prognostic value of Porphyromonas gingivalis infection in lung cancer	29
The clinical value of the changes of peripheral lymphocyte subsets absolute counts in patients with non-small cell lung cancer	29
Synthesis of 99mTc-labeled 2-Mercaptobenzimidazole as a novel radiotracer to diagnose tumor hypoxia	29
Deep learning for predicting subtype classification and survival of lung adenocarcinoma on computed tomography	29
Photodynamic therapy exploiting the anti-tumor activity of mannose-conjugated chlorin e6 reduced M2-like tumor-associated macrophages	29
IRF2 regulates cellular survival and Lenvatinib-sensitivity of hepatocellular carcinoma (HCC) through regulating β-catenin	29
Multiparametric MRI-based radiomics analysis for the prediction of breast tumor regression patterns after neoadjuvant chemotherapy	28
FYN promotes gastric cancer metastasis by activating STAT3-mediated epithelial-mesenchymal transition	28
Clinical use and mechanisms of resistance for PARP inhibitors in homologous recombination-deficient cancers	28
Construction of a prognostic immune signature for lower grade glioma that can be recognized by MRI radiomics features to predict survival in LGG patients	27
An upward 9.4 T static magnetic field inhibits DNA synthesis and increases ROS-P53 to suppress lung cancer growth	27
The Pan-Immune-Inflammation Value predicts the survival of patients with anaplastic lymphoma kinase-positive non-small cell lung cancer treated with first-line ALK inhibitor	27
FGF9/FGFR1 promotes cell proliferation, epithelial-mesenchymal transition, M2 macrophage infiltration and liver metastasis of lung cancer	27
The PER1/HIF-1alpha negative feedback loop promotes ferroptosis and inhibits tumor progression in oral squamous cell carcinoma	26
Crosstalk between oral squamous cell carcinoma cells and cancer-associated fibroblasts via the TGF-β/SOX9 axis in cancer progression	26
Novel artificial intelligence machine learning approaches to precisely predict survival and site-specific recurrence in cervical cancer: A multi-institutional study	26
MALAT-1: Immunomodulatory lncRNA hampering the innate and the adaptive immune arms in triple negative breast cancer	26
Analysis of genomics and immune infiltration patterns of epithelial-mesenchymal transition related to metastatic breast cancer to bone	26
Non-coding RNAs in pancreatic ductal adenocarcinoma: New approaches for better diagnosis and therapy	25
Knockdown of CDK5 down-regulates PD-L1 via the ubiquitination-proteasome pathway and improves antitumor immunity in lung adenocarcinoma	25
Advances in PSMA theranostics	25
Driverless artificial intelligence framework for the identification of malignant pleural effusion	25
A novel dominant-negative PD-1 armored anti-CD19 CAR T cell is safe and effective against refractory/relapsed B cell lymphoma	24
Extracellular vesicle-mediated transport: Reprogramming a tumor microenvironment conducive with breast cancer progression and metastasis	24
Chemotherapeutic drugs: Cell death- and resistance-related signaling pathways. Are they really as smart as the tumor cells?	23
FOXO3a inhibits the EMT and metastasis of breast cancer by regulating TWIST-1 mediated miR-10b/CADM2 axis	23
Radiotherapy: Brightness and darkness in the era of immunotherapy	23
Targeted inhibition of glutamine metabolism enhances the antitumor effect of selumetinib in KRAS-mutant NSCLC	23
Novel prognostic model established for patients with head and neck squamous cell carcinoma based on pyroptosis-related genes	23

Emerging roles for HMGA2 in colorectal cancer	23
Remote controlling of CAR-T cells and toxicity management: Molecular switches and next generation CARs	23
Diagnostic assessment of deep learning for melanocytic lesions using whole-slide pathological images	23
Prediction of post-radiotherapy locoregional progression in HPV-associated oropharyngeal squamous cell carcinoma using machine-learning analysis of baseline PET/CT radiomics	22
LncRNA HOTAIR recruits SNAIL to inhibit the transcription of HNF4α and promote the viability, migration, invasion and EMT of colorectal cancer	22
Thioredoxin reductase: An emerging pharmacologic target for radiosensitization of cancer	22
Exosomal miR-193a and let-7g accelerate cancer progression on primary colorectal cancer and paired peritoneal metastatic cancer	22
Will the clinical development of 4th-generation “double mutant active” ALK TKIs (TPX-0131 and NVL-655) change the future treatment paradigm of ALK+ NSCLC?	22
Clinical relevance of oncogenic driver mutations identified in endometrial carcinoma	22
Exploring the utility of extracellular vesicles in ameliorating viral infection-associated inflammation, cytokine storm and tissue damage	22
Ultrasound-mediated microbubbles cavitation enhanced chemotherapy of advanced prostate cancer by increasing the permeability of blood-prostate barrier	21
Tumor-targeting anti-EGFR x anti-PD1 bispecific antibody inhibits EGFR-overexpressing tumor growth by combining EGFR blockade and immune activation with direct tumor cell killing	21
Regulation of CD47 expression by interferon-gamma in cancer cells	21
KRAS and PIK3CA bi-mutations predict a poor prognosis in colorectal cancer patients: A single-site report	21
GD2-specific chimeric antigen receptor-modified T cells targeting retinoblastoma – assessing tumor and T cell interaction	21
The role of von Willebrand factor in breast cancer metastasis	21
Addition of TLR9 agonist immunotherapy to radiation improves systemic antitumor activity	21
Machine-learning analysis of contrast-enhanced computed tomography radiomics predicts patients with hepatocellular carcinoma who are unsuitable for initial transarterial chemoembolization monotherapy:	20
MicroRNA-506-3p increases the response to PARP inhibitors and cisplatin by targeting EZH2/β-catenin in serous ovarian cancers	20
LncRNA CRNDE promotes the progression and angiogenesis of pancreatic cancer via miR-451a/CDKN2D axis	20
Chronological age or biological age: What drives the choice of adjuvant treatment in elderly breast cancer patients?	20
Hypoxia-induced phenotypic transition from highly invasive to less invasive tumors in glioma stem-like cells: Significance of CD44 and osteopontin as therapeutic targets in glioblastoma	20
Transitional dynamics of cancer stem cells in invasion and metastasis	20
LncRNA PDCD4-AS1 alleviates triple negative breast cancer by increasing expression of IQGAP2 via miR-10b-5p	20
Therapeutic potential of Fingolimod in triple negative breast cancer preclinical models	20
A zinc finger family protein, ZNF263, promotes hepatocellular carcinoma resistance to apoptosis via activation of ER stress-dependent autophagy	20
The molecular mechanism of chronic stress affecting the occurrence and development of breast cancer and potential drug therapy	20
Targeting miR-9 in Glioma Stem Cell-Derived Extracellular Vesicles: A Novel Diagnostic and Therapeutic Biomarker	19
Melatonin increases the chemosensitivity of diffuse large B-cell lymphoma cells to epirubicin by inhibiting P-glycoprotein expression via the NF-κB pathway	19
Comparative analysis of triple-negative breast cancer transcriptomics of Kenyan, African American and Caucasian Women	19
iNKT: A new avenue for CAR-based cancer immunotherapy	19
The predictive efficacy of tumor mutation burden in immunotherapy across multiple cancer types: A meta-analysis and bioinformatics analysis	19
Overexpression of CEACAM6 activates Src-FAK signaling and inhibits anoikis, through homophilic interactions in lung adenocarcinomas	19
PRF1 is a prognostic marker and correlated with immune infiltration in head and neck squamous cell carcinoma	19
Machine learning analysis using 77,044 genomic and transcriptomic profiles to accurately predict tumor type	19
Enhanced toxicity with CDK 4/6 inhibitors and palliative radiotherapy: Non-consecutive case series and review of the literature	19
Bioengineered microfluidic blood-brain barrier models in oncology research	19
Single-cell RNA-seq analysis to identify potential biomarkers for diagnosis, and prognosis of non-small cell lung cancer by using comprehensive bioinformatics approaches	18
Searching for the real function of mTOR signaling in the regulation of PD-L1 expression	18
USP8 regulates liver cancer progression via the inhibition of TRAF6-mediated signal for NF-κB activation and autophagy induction by TLR4	18
Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy	18
Nephrotoxicity after radionuclide therapies	18
Genetic regressive trajectories in colorectal cancer: A new hallmark of oligo-metastatic disease?	18
Extracellular vesicle-orchestrated crosstalk between cancer-associated fibroblasts and tumors	18
A label-free microfluidic chip for the highly selective isolation of single and cluster CTCs from breast cancer patients	17
Exosomes: Insights and therapeutic applications in cancer	17
A clinical and molecular portrait of non-metastatic anal squamous cell carcinoma	17
A novel PAK4 inhibitor suppresses pancreatic cancer growth and enhances the inhibitory effect of gemcitabine	17
FLT3 inhibition by olverembatinib (HQP1351) downregulates MCL-1 and synergizes with BCL-2 inhibitor lisaftoclax (APG-2575) in preclinical models of FLT3-ITD mutant acute myeloid leukemia	17
CPT2 down-regulation promotes tumor growth and metastasis through inducing ROS/NFκB pathway in ovarian cancer	17
Thrombotic microangiopathy in oncology – a review	17
Enhanced expression of GABRD predicts poor prognosis in patients with colon adenocarcinoma	17
Tumor-targeted pH-low insertion peptide delivery of theranostic gadolinium nanoparticles for image-guided nanoparticle-enhanced radiation therapy	17
Abnormal alternative splicing promotes tumor resistance in targeted therapy and immunotherapy	17
Nanoscale biomaterials for terahertz imaging: A non-invasive approach for early cancer detection	16
Acetyl-CoA synthetases ACSS1 and ACSS2 are 4-hydroxytamoxifen responsive factors that promote survival in tamoxifen treated and estrogen deprived cells	16
Targeting CD276 by CAR-T cells induces regression of esophagus squamous cell carcinoma in xenograft mouse models	16
Onodera's prognostic nutritional index correlates with tumor immune environment and survival in patients with oral squamous cell carcinoma undergoing chemoradiotherapy	16
MicroRNAs and long non-coding RNAs in pancreatic cancer: From epigenetics to potential clinical applications	16
Energy metabolism pathways in breast cancer progression: The reprogramming, crosstalk, and potential therapeutic targets	16
Gene expression profiles of inflammatory breast cancer reveal high heterogeneity across the epithelial-hybrid-mesenchymal spectrum	16
Predicting oncogene mutations of lung cancer using deep learning and histopathologic features on whole-slide images	16
Preoperative prediction of microvascular invasion in non-metastatic hepatocellular carcinoma based on nomogram analysis	16
MicroRNAs as clinical tools for diagnosis, prognosis, and therapy in prostate cancer	16
Fatty acid binding protein-4 promotes alcohol-dependent hepatosteatosis and hepatocellular carcinoma progression	16
Long non-coding RNA HNF1A-AS1 induces 5-FU resistance of gastric cancer through miR-30b-5p/EIF5A2 pathway	16
Saliva as a potential non-invasive liquid biopsy for early and easy diagnosis/prognosis of head and neck cancer	16
An overview of prostate cancer (PCa) diagnosis: Potential role of miRNAs	16
Successful application of anti-CD19 CAR-T therapy with IL-6 knocking down to patients with central nervous system B-cell acute lymphocytic leukemia	16
Computed tomography-based radiomic model at node level for the prediction of normal-sized lymph node metastasis in cervical cancer	16
Characterization of stanniocalcin-1 expression in macrophage differentiation	15
Concerning FDA approval of trilaciclib (Cosela) in extensive-stage small-cell lung cancer	15
Factors associated with immunotherapy respond and survival in advanced non-small cell lung cancer patients	15
MET exon 14 skipping mutation, amplification and overexpression in pulmonary sarcomatoid carcinoma: A multi-center study	15
Chemical complementarity between immune receptors and cancer mutants, independent of antigen presentation protein binding, is associated with increased survival rates	15
Tebentafusp in first-line melanoma trials: An outperforming outlier	15
Anti-tumor effect of carrimycin on oral squamous cell carcinoma cells in vitro and in vivo	15
Exploitation of the vitamin A/retinoic acid axis depletes ALDH1-positive cancer stem cells and re-sensitises resistant non-small cell lung cancer cells to cisplatin	15
ZG16 regulates PD-L1 expression and promotes local immunity in colon cancer	15
The combination therapy of oncolytic HSV-1 armed with anti-PD-1 antibody and IL-12 enhances anti-tumor efficacy	15

Synergistic effect of sodium butyrate and oxaliplatin on colorectal cancer	15
The potential role of cofilin-1 in promoting triple negative breast cancer (TNBC) metastasis via the extracellular vesicles (EVs)	15
Metaplastic breast cancer: Treatment and prognosis by molecular subtype	15
Integrative single-cell transcriptome analysis reveals a subpopulation of fibroblasts associated with favorable prognosis of liver cancer patients	15
Pulmonary enteric adenocarcinoma	15
Absent in melanoma 2-mediating M1 macrophages facilitate tumor rejection in renal carcinoma	15
Early risk-assessment of patients with nasopharyngeal carcinoma: the added prognostic value of MR-based radiomics	14
Survival prediction and response to immune checkpoint inhibitors: A prognostic immune signature for hepatocellular carcinoma	14
Construction and validation of a risk scoring model for diffuse large B-cell lymphoma based on ferroptosis-related genes and its association with immune infiltration	14
Low-dose naltrexone plays antineoplastic role in cervical cancer progression through suppressing PI3K/AKT/mTOR pathway	14
Targeting tumor microenvironment for cholangiocarcinoma: Opportunities for precision medicine	14
XPO1 inhibition with selinexor synergizes with proteasome inhibition in neuroblastoma by targeting nuclear export of IkB	14
A signature of 17 immune-related gene pairs predicts prognosis and immune status in HNSCC patients	14
TNFR1 and the TNFα axis as a targetable mediator of liver injury from stereotactic body radiation therapy	14
Prediction of chemotherapy response in breast cancer patients at pre-treatment using second derivative texture of CT images and machine learning	14
Systemic levels of the soluble co-inhibitory immune checkpoints, CTLA-4, LAG-3, PD-1/PD-L1 and TIM-3 are markedly increased in basal cell carcinoma	14
Distinct tumor bacterial microbiome in lung adenocarcinomas manifested as radiological subsolid nodules	14
Liraglutide activates nature killer cell-mediated antitumor responses by inhibiting IL-6/STAT3 signaling in hepatocellular carcinoma	14
Overlapping targets exist between the Par-4 and miR-200c axis which regulate EMT and proliferation of pancreatic cancer cells	14
Biomarkers of response to ibrutinib plus nivolumab in relapsed diffuse large B-cell lymphoma, follicular lymphoma, or Richter's transformation	14
Efficacy and safety of apatinib for the treatment of AFP-producing gastric cancer	14
A higher platelet-to-lymphocyte ratio is prevalent in the presence of circulating tumor microemboli and is a potential prognostic factor for non-metastatic colon cancer	14
Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML	14
Prognostic implications of ENE and LODDS in relation to lymph node-positive colorectal cancer location	14
Aminoacyl-tRNA synthetases of the multi-tRNA synthetase complex and their role in tumorigenesis	14
Luteolin promotes macrophage-mediated phagocytosis by inhibiting CD47 pyroglutamation	13
LncRNA DLGAP1-AS2 promotes the radioresistance of rectal cancer stem cells by upregulating CD151 expression via E2F1	13
Radiomics nomogram: A noninvasive tool for preoperative evaluation of the invasiveness of pulmonary adenocarcinomas manifesting as ground-glass nodules	13
LncRNA RBPMS-AS1 promotes NRGN transcription to enhance the radiosensitivity of glioblastoma through the microRNA-301a-3p/CAMTA1 axis	13
Longitudinal radiomics algorithm of posttreatment computed tomography images for early detecting recurrence of hepatocellular carcinoma after resection or ablation	13
Antitumor efficacy of XPO1 inhibitor Selinexor in KRAS-mutant lung adenocarcinoma patient-derived xenografts	13
Current clinical trials with non-coding RNA-based therapeutics in malignant diseases: A systematic review	13
Non-coding RNAs in cancer-associated cachexia: clinical implications and future perspectives	13
Hopes on immunotherapy targeting B7-H3 in neuroblastoma	13
68Ga-PSMA-HBED-CC PET/MRI is superior to multiparametric magnetic resonance imaging in men with biochemical recurrent prostate cancer: A prospective single-institutional study	13
PTPN3 is a potential target for a new cancer immunotherapy that has a dual effect of T cell activation and direct cancer inhibition in lung neuroendocrine tumor	13
Current landscape and perspective of oncolytic viruses and their combination therapies	13
UAE1 inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer	13
Advances in the treatment of extramedullary disease in multiple myeloma	13
Resistance against anti-CD19 and anti-BCMA CAR T cells: Recent advances and coping strategies	13
Multimarker scores of Th1 and Th2 immune cellular profiles in peripheral blood predict response and immune related toxicity with CTLA4 blockade and IFNα in melanoma	13
Downregulation of miR-221–3p promotes the ferroptosis in gastric cancer cells via upregulation of ATF3 to mediate the transcription inhibition of GPX4 and HRD1	13
R-loop modulated epigenetic regulation in T helper cells mechanistically associates coronary artery disease and non-small cell lung cancer	13
Glucose 6-phosphate dehydrogenase inhibition sensitizes melanoma cells to metformin treatment	13
Hsa_circ_0088212-mediated miR-520 h/APOA1 axis inhibits osteosarcoma progression	13
HPV+ve/−ve oral-tongue cancer stem cells: A potential target for relapse-free therapy	13
Telomerase inhibitor MST-312 and quercetin synergistically inhibit cancer cell proliferation by promoting DNA damage	13
Collagen modifying enzyme P4HA1 is overexpressed and plays a role in lung adenocarcinoma	13
Optimal timing of combining sorafenib with trans-arterial chemoembolization in patients with hepatocellular carcinoma: A meta-analysis	12
Bazedoxifene inhibits sustained STAT3 activation and increases survival in GBM	12
Tumor microenvironment disparity in multiple primary lung cancers: Impact of non-intrinsic factors, histological subtypes, and genetic aberrations	12
Chondroitin sulfate proteoglycan 4, a targetable oncoantigen that promotes ovarian cancer growth, invasion, cisplatin resistance and spheroid formation	12
Beta-adrenergic pathway activation enhances aggressiveness and inhibits stemness in head and neck cancer	12
Genome-wide analysis of copy number alterations led to the characterisation of PDCD10 as oncogene in ovarian cancer	12
Macrophage polarization synergizes with oxaliplatin in lung cancer immunotherapy via enhanced tumor cell phagocytosis	12
IGFBP3 inhibits tumor growth and invasion of lung cancer cells and is associated with improved survival in lung cancer patients	12
p.G12C KRAS mutation prevalence in non-small cell lung cancer: Contribution from interregional variability and population substructures among Hispanics	12
Progress on carbon dots and hydroxyapatite based biocompatible luminescent nanomaterials for cancer theranostics	12
Invasive phenotype in triple negative breast cancer is inhibited by blocking SIN3A–PF1 interaction through KLF9 mediated repression of ITGA6 and ITGB1	12
A novel vitamin D gene therapy for acute myeloid leukemia	12
Radiosensitizing effect of gold nanoparticle loaded with small interfering RNA-SP1 on lung cancer	12
Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma	12
Detection of oncogenic mutations in paired circulating tumor DNA and circulating tumor cells in patients with hepatocellular carcinoma	12
BX-795 inhibits neuroblastoma growth and enhances sensitivity towards chemotherapy	12
Blood and neuroimaging biomarkers of cognitive sequelae in breast cancer patients throughout chemotherapy: A systematic review	12
Chondrocyte-derived Exosomal miR-195 Inhibits Osteosarcoma Cell Proliferation and Anti-Apoptotic by Targeting KIF4A in vitro and in vivo	12
Implementing biological markers as a tool to guide clinical care of patients with pancreatic cancer	12
Epigenetic modifications: Key players in cancer heterogeneity and drug resistance	12
3D heterospecies spheroids of pancreatic stroma and cancer cells demonstrate key phenotypes of pancreatic ductal adenocarcinoma	12
Platelet transfusion for cancer secondary thrombocytopenia: Platelet and cancer cell interaction	12
Lymphocyte subsets in haematological patients with COVID-19: Multicentre prospective study	12
Rova-T enhances the anti-tumor activity of anti-PD1 in a murine model of small cell lung cancer with endogenous Dll3 expression	12
miR-376a inhibits glioma proliferation and angiogenesis by regulating YAP1/VEGF signalling via targeting of SIRT1	12
Chemotherapy regimens induce inhibitory immune checkpoint protein expression on stem-like and senescent-like oesophageal adenocarcinoma cells	12
STRN-ALK rearranged pediatric malignant peritoneal mesothelioma – Functional testing of 527 cancer drugs in patient-derived cancer cells	12
Oncometabolite lactate enhances breast cancer progression by orchestrating histone lactylation-dependent c-Myc expression	12
Genomic profiling of solid tumors harboring BRD4-NUT and response to immune checkpoint inhibitors	12
Inhibition of DCLK1 kinase reverses epithelial-mesenchymal transition and restores T-cell activity in pancreatic ductal adenocarcinoma	12
Cytotoxicity of combinations of the pan-KRAS inhibitor BAY-293 against primary non-small lung cancer cells	12
Non-enzymatic glycoxidation linked with nutrition enhances the tumorigenic capacity of prostate cancer epithelia through AGE mediated activation of RAGE in cancer associated fibroblasts	12
Human β-defensin-3 and nuclear factor-kappa B p65 synergistically promote the cell proliferation and invasion of oral squamous cell carcinoma	12
Typical tumor immune microenvironment status determine prognosis in lung adenocarcinoma	12
TIM3 expression on tumor cells predicts response to anti-PD-1 therapy for renal cancer	12
Vanucizumab mode of action: Serial biomarkers in plasma, tumor, and skin-wound-healing biopsies	12
Expression pattern analysis and drug differential sensitivity of cancer-associated fibroblasts in triple-negative breast cancer	11
Tumor mutation burden in the prognosis and response of lung cancer patients to immune-checkpoint inhibition therapies	11
Anti-GD2 CAR MSCs against metastatic Ewing's sarcoma	11
Sacituzumab govitecan in metastatic triple negative breast cancer (TNBC): Four design features in the ASCENT trial potentially favored the experimental arm	11
Obatoclax, the pan-Bcl-2 inhibitor sensitizes hepatocellular carcinoma cells to promote the anti-tumor efficacy in combination with immune checkpoint blockade	11
CT-based radiomics model with machine learning for predicting primary treatment failure in diffuse large B-cell Lymphoma	11
Lung cancer and oncolytic virotherapy——enemy's enemy	11
Circulating microRNAs as biomarkers to assist the management of the malignant germ-cell-tumour subtype choriocarcinoma	11
In situ immunopathological events in human cervical intraepithelial neoplasia and cervical cancer: Review	11
Type of chemotherapy has substantial effects on the immune system in ovarian cancer	11
TSPAN31 regulates the proliferation, migration, and apoptosis of gastric cancer cells through the METTL1/CCT2 pathway	11