OOIR: Observatory of International Research

Papers

(The H4-Index of Translational Oncology is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
ERβ-regulated circATP2B1/miR-204–3p/TWIST1 positive feedback loop facilitates epithelial to mesenchymal transition in clear cell renal cell carcinoma	210
Radiation from frequent whole-body CT scans induces systemic immunosuppression and immune activation of tumor tissue	116
Interplay between Caveolin-1 and body and tumor size affects clinical outcomes in breast cancer	116
LncRNA DGUOK-AS1 facilitates non-small cell lung cancer growth and metastasis through increasing TRPM7 stability via m6A modification	99
Predictive value of peripheral blood leukocytes-based methylation of Long non-coding RNA MALAT1 and H19 in the chemotherapy effect and prognosis of gastric cancer	90
ALYREF associated with immune infiltration is a prognostic biomarker in hepatocellular carcinoma	86
Integrated multi-omics demonstrates enhanced antitumor efficacy of donafenib combined with FADS2 inhibition in hepatocellular carcinoma	73
The Potential Role of C4 MYH11+ Fibroblasts and the MDK-SDC2 Ligand-Receptor Pair in Lung Adenocarcinoma: Implications for Prognosis and Therapeutic Strategies	72
A Novel Epigenetic Strategy to Concurrently Block Immune Checkpoints PD-1/PD-L1 and CD155/TIGIT in Hepatocellular Carcinoma	61
CD44 occurring alternative splicing promotes cisplatin resistance and evokes tumor immune response in oral squamous cell carcinoma cells	59
Identification of IMPA2 as the hub gene associated with colorectal cancer and liver metastasis by integrated bioinformatics analysis	57
The double face of cold in cancer	57
A novel telomerase-derived peptide GV1001-mediated inhibition of angiogenesis: Regulation of VEGF/VEGFR-2 signaling pathways	57
Investigating the molecular mechanisms and clinical potential of APO+ endothelial cells associated with PANoptosis in the tumor microenvironment of hepatocellular carcinoma using single-cell sequencin	55
Identification of metastasis-associated exoDEPs in colorectal cancer using label-free proteomics	54
Corrigendum to “Genomic profiles and their relationships with clinical characteristics and immune features in cervical cancer” [Translational Oncology 44 (2024) 1–10/101923]	50
GSDME has prognostic and immunotherapeutic significance in residual hepatocellular carcinoma after insufficient radiofrequency ablation	48
Pan-cancer analysis of super-enhancer-induced LINC00862 and validation as a SIRT1-promoting factor in cervical cancer and gastric cancer	47
HDAC inhibitor (SAHA) enhances B7-H3-specific CAR T cell cytotoxic efficacy against chondrosarcoma cells and prolongs survival in an orthotopic mouse model	47
Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma	46
Single-treatment tumor ablation with photodynamic liposomal irinotecan sucrosulfate	45
Connexin43 is associated with the progression of clear cell renal carcinoma and is regulated by tangeretin to sygergize with tyrosine kinase inhibitors	42
Commentary: Machine learning developed an intratumor heterogeneity signature for predicting prognosis and immunotherapy benefits in cholangiocarcinoma	41
miR-1182-mediated ALDH3A2 inhibition affects lipid metabolism and progression in ccRCC by activating the PI3K-AKT pathway	41
Development of a single-cell derived MDSCs signature score for prognostic risk stratification and therapeutic decision guidance in breast cancer	38

Clinical characteristics and treatment efficacy of immune checkpoint inhibitors (ICIs) in patients with ICIs-induced Adrenal insufficiency	38
Predicting lymphoma prognosis using machine learning-based genes associated with lactylation	37
FUBP1 in human cancer: Characteristics, functions, and potential applications	37
Association of PIK3CA mutation with outcomes in HER2-positive breast cancer treated with anti-HER2 therapy: A meta-analysis and bioinformatic analysis of TCGA‑BRCA data	36
CD38 overexpression drives glioblastoma progression via L1CAM/ICAM1/JAK-STAT-Driven tumor microenvironment rewiring	36
XIAP overexpressing inflammatory breast cancer patients have high infiltration of immunosuppressive subsets and increased TNFR1 signaling targetable with Birinapant	34
Loss of p53 epigenetically modulates epithelial to mesenchymal transition in colorectal cancer	34
Anti-PD-1/PD-L1 therapy for colorectal cancer: Clinical implications and future considerations	34
Single-cell insights into HNSCC tumor heterogeneity and programmed cell death pathways	33
Exploration of the mechanism of 5-Methylcytosine promoting the progression of hepatocellular carcinoma	33
NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma	33