OOIR: Observatory of International Research

Papers

(The TQCC of Annual Review of Biophysics is 32. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Free Energy Methods for the Description of Molecular Processes	183
Enzymology and Dynamics by Cryogenic Electron Microscopy	171
Mapping Enzyme Landscapes by Time-Resolved Crystallography with Synchrotron and X-Ray Free Electron Laser Light	115
The Effects of Temperature on Cellular Physiology	114
Membrane Association of Intrinsically Disordered Proteins	111
Mechanism of Activation of the Visual Receptor Rhodopsin	110
Biophysical Modeling of Synaptic Plasticity	96
ATP-Independent Chaperones	79
The Expanded Central Dogma: Genome Resynthesis, Orthogonal Biosystems, Synthetic Genetics	63
Nanomechanics of Blood Clot and Thrombus Formation	57
From Nucleosomes to Compartments: Physicochemical Interactions Underlying Chromatin Organization	47
Collapse and Protein Folding: Should We Be Surprised That Biothermodynamics Works So Well?	47
Molecular Shape Solution for Mesoscopic Remodeling of Cellular Membranes	46
Chaperonin Mechanisms: Multiple and (Mis)Understood?	46
Next-Generation Genetically Encoded Fluorescent Biosensors Illuminate Cell Signaling and Metabolism	46
Prospects and Limitations of High-Resolution Single-Particle Cryo-Electron Microscopy	42
Structure and Mechanism of Human ABC Transporters	41
Waves in Embryonic Development	40
Bacterial Electrophysiology	38
Bioenergetics and the Evolution of Cellular Traits	38
Molecular Mechanisms Underlying Neurotransmitter Release	34
Bringing Structure to Cell Biology with Cryo-Electron Tomography	34
Unveiling the Intricate Connection: Cell Volume as a Key Regulator of Mechanotransduction	33
Cholesterol and Lipid Rafts in the Biogenesis of Amyloid-β Protein and Alzheimer's Disease	32
Mechanisms for DNA Interplay in Eukaryotic Transcription Factors	32

Statistical Thermodynamics of the Protein Ensemble: Mediating Function and Evolution