OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Biophysics is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Free Energy Methods for the Description of Molecular Processes	229
Enzymology and Dynamics by Cryogenic Electron Microscopy	206
The Effects of Temperature on Cellular Physiology	163
Mapping Enzyme Landscapes by Time-Resolved Crystallography with Synchrotron and X-Ray Free Electron Laser Light	163
Biophysical Modeling of Synaptic Plasticity	138
The Expanded Central Dogma: Genome Resynthesis, Orthogonal Biosystems, Synthetic Genetics	128
Mechanism of Activation of the Visual Receptor Rhodopsin	126
ATP-Independent Chaperones	92
Membrane Association of Intrinsically Disordered Proteins	85
Nanomechanics of Blood Clot and Thrombus Formation	81
Tethered Signaling Proteins	68
Next-Generation Genetically Encoded Fluorescent Biosensors Illuminate Cell Signaling and Metabolism	62
Structures of Photosynthetic Supramolecular Complexes	57
Collapse and Protein Folding: Should We Be Surprised That Biothermodynamics Works So Well?	56
From Nucleosomes to Compartments: Physicochemical Interactions Underlying Chromatin Organization	55
Chaperonin Mechanisms: Multiple and (Mis)Understood?	53
Molecular Shape Solution for Mesoscopic Remodeling of Cellular Membranes	50
Prospects and Limitations of High-Resolution Single-Particle Cryo-Electron Microscopy	47
Structure and Mechanism of Human ABC Transporters	47
The Mitochondrial Permeability Transition Pore: Past, Present, and Future	46
Bacterial Electrophysiology	45
Waves in Embryonic Development	45
Imaging Dynamic Subcellular Organization at High Spatiotemporal Resolution	45
Molecular Mechanisms Underlying Neurotransmitter Release	44
Unveiling the Intricate Connection: Cell Volume as a Key Regulator of Mechanotransduction	41

Bringing Structure to Cell Biology with Cryo-Electron Tomography	41
Bioenergetics and the Evolution of Cellular Traits	41
Hopfield Networks as Models of Emergent Function in Biology	40
Mechanisms for DNA Interplay in Eukaryotic Transcription Factors	40
Statistical Thermodynamics of the Protein Ensemble: Mediating Function and Evolution	39
Cholesterol and Lipid Rafts in the Biogenesis of Amyloid-β Protein and Alzheimer's Disease	39
Coding From Binding? Molecular Interactions at the Heart of Translation	37
Information Processing in Biochemical Networks	36
Metabolic Engineering of Yeast	34
Structure Function Studies of Photosystem II Using X-Ray Free Electron Lasers	32
Single-Cell Proteomic Technologies: Tools in the Quest for Principles	31
Protein Modeling with DEER Spectroscopy	31
Morphology and Transport in Eukaryotic Cells	29
Metabolomics and Microbial Metabolism: Toward a Systematic Understanding	29
Ancestral Reconstruction and the Evolution of Protein Energy Landscapes	27
Mitochondrial Outer Membrane Voltage-Dependent Anion Channels: Unique Structures, Distinct Functions, and Novel Therapeutic Targets	25
Toward Principles of Brain Network Organization and Function	24
Emergent Spatiotemporal Organization in Stochastic Intracellular Transport Dynamics	21
Quantitative Single-Molecule Localization Microscopy	21
Fold-Switching Proteins	20
Variable-Temperature Native Mass Spectrometry for Studies of Protein Folding, Stabilities, Assembly, and Molecular Interactions	20
Single-Molecule Imaging of Integral Membrane Protein Dynamics and Function	20
Decoding and Recoding of mRNA Sequences by the Ribosome	20
Mitochondrial Dynamics at Different Levels: From Cristae Dynamics to Interorganellar Cross Talk	19
Cryo-EM of Mitochondrial Complex I and ATP Synthase	19
Orientation of Cell Polarity by Chemical Gradients	18
Fifty Years of Biophysics at the Membrane Frontier	18
Cryo-Electron Tomography: The Resolution Revolution and a Surge of In Situ Virological Discoveries	18
Ligand Binding Dynamics of Ion Channels and GPCRs Using Single-Molecule Fluorescence	18
Single-Cell Mechanics: Structural Determinants and Functional Relevance	17
Insights into the Thermodynamics and Kinetics of Amino-Acid Radicals in Proteins	17
	16
Size Matters: A Biophysical Perspective on Biomolecular Condensates in Bacteria	16