OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Biophysics is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Free Energy Methods for the Description of Molecular Processes	183
Enzymology and Dynamics by Cryogenic Electron Microscopy	171
Mapping Enzyme Landscapes by Time-Resolved Crystallography with Synchrotron and X-Ray Free Electron Laser Light	115
The Effects of Temperature on Cellular Physiology	114
Membrane Association of Intrinsically Disordered Proteins	111
Mechanism of Activation of the Visual Receptor Rhodopsin	110
Biophysical Modeling of Synaptic Plasticity	96
ATP-Independent Chaperones	79
The Expanded Central Dogma: Genome Resynthesis, Orthogonal Biosystems, Synthetic Genetics	63
Nanomechanics of Blood Clot and Thrombus Formation	57
From Nucleosomes to Compartments: Physicochemical Interactions Underlying Chromatin Organization	47
Collapse and Protein Folding: Should We Be Surprised That Biothermodynamics Works So Well?	47
Chaperonin Mechanisms: Multiple and (Mis)Understood?	46
Next-Generation Genetically Encoded Fluorescent Biosensors Illuminate Cell Signaling and Metabolism	46
Molecular Shape Solution for Mesoscopic Remodeling of Cellular Membranes	46
Prospects and Limitations of High-Resolution Single-Particle Cryo-Electron Microscopy	42
Structure and Mechanism of Human ABC Transporters	41
Waves in Embryonic Development	40
Bioenergetics and the Evolution of Cellular Traits	38
Bacterial Electrophysiology	38
Molecular Mechanisms Underlying Neurotransmitter Release	34
Bringing Structure to Cell Biology with Cryo-Electron Tomography	34
Unveiling the Intricate Connection: Cell Volume as a Key Regulator of Mechanotransduction	33
Mechanisms for DNA Interplay in Eukaryotic Transcription Factors	32
Statistical Thermodynamics of the Protein Ensemble: Mediating Function and Evolution	32

Cholesterol and Lipid Rafts in the Biogenesis of Amyloid-β Protein and Alzheimer's Disease	32
Information Processing in Biochemical Networks	31
Metabolic Engineering of Yeast	30
Structure Function Studies of Photosystem II Using X-Ray Free Electron Lasers	30
Coding From Binding? Molecular Interactions at the Heart of Translation	28
Metabolomics and Microbial Metabolism: Toward a Systematic Understanding	27
Morphology and Transport in Eukaryotic Cells	27
Ancestral Reconstruction and the Evolution of Protein Energy Landscapes	26
Protein Modeling with DEER Spectroscopy	26
Toward Principles of Brain Network Organization and Function	25
Quantitative Single-Molecule Localization Microscopy	25
Emergent Spatiotemporal Organization in Stochastic Intracellular Transport Dynamics	23
Variable-Temperature Native Mass Spectrometry for Studies of Protein Folding, Stabilities, Assembly, and Molecular Interactions	23
Single-Molecule Imaging of Integral Membrane Protein Dynamics and Function	22
Cryo-EM of Mitochondrial Complex I and ATP Synthase	22
Mitochondrial Dynamics at Different Levels: From Cristae Dynamics to Interorganellar Cross Talk	19
Decoding and Recoding of mRNA Sequences by the Ribosome	18
Orientation of Cell Polarity by Chemical Gradients	17
Insights into the Thermodynamics and Kinetics of Amino-Acid Radicals in Proteins	16
Cryo-Electron Tomography: The Resolution Revolution and a Surge of In Situ Virological Discoveries	16
Fifty Years of Biophysics at the Membrane Frontier	15
Mechanisms of Inheritance of Chromatin States: From Yeast to Human	14
Single-Cell Mechanics: Structural Determinants and Functional Relevance	14