OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Stem Cell is 79. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Pluripotent Stem Cell-Based Cell Therapy—Promise and Challenges	603
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids	516
SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids	374
Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease	331
Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration	307
Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium	292
Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction	274
Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation	264
SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response	250
The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future	228
RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia	216
Human naive epiblast cells possess unrestricted lineage potential	194
Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2	190
Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Hematopoiesis	181
Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer	174
Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity	173
Capturing Cardiogenesis in Gastruloids	164
Chronic infection drives Dnmt3a-loss-of-function clonal hematopoiesis via IFNγ signaling	163
Capturing human trophoblast development with naive pluripotent stem cells in vitro	162
C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells	159
Naive stem cell blastocyst model captures human embryo lineage segregation	159
Mitochondria as Signaling Organelles Control Mammalian Stem Cell Fate	154
ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response	152
Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair	148
Implanted pluripotent stem-cell-derived pancreatic endoderm cells secrete glucose-responsive C-peptide in patients with type 1 diabetes	147

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids	144
Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men	140
Tissue Stem Cells: Architects of Their Niches	138
Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency	136
Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis	136
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids	132
CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank	132
Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells	129
CD276 expression enables squamous cell carcinoma stem cells to evade immune surveillance	128
Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids	127
Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Cancer Cells in Myeloproliferative Neoplasms	125
Wound healing, fibroblast heterogeneity, and fibrosis	121
Aging and Rejuvenation of Neural Stem Cells and Their Niches	119
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients	117
Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells	116
The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma	116
Mesenchymal stromal cells: Putative microenvironmental modulators become cell therapy	115
Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01	114
Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes	111
Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer	110
Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing	110
Smooth Muscle Cell Reprogramming in Aortic Aneurysms	109
Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription	109
Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification	108
Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification	108
Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors	108
Neural Stem Cell Grafts Form Extensive Synaptic Networks that Integrate with Host Circuits after Spinal Cord Injury	105
Establishment, maintenance, and recall of inflammatory memory	104
Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment	103
Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population	103
Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use	101
Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids	101
Membrane Tension Gates ERK-Mediated Regulation of Pluripotent Cell Fate	100
Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder	99
Quantitative evaluation of chromosomal rearrangements in gene-edited human stem cells by CAST-Seq	95
Mapping Development of the Human Intestinal Niche at Single-Cell Resolution	92
CRISPR-Cas Tools and Their Application in Genetic Engineering of Human Stem Cells and Organoids	91
Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging	89
Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome	89
Resolving Fates and Single-Cell Transcriptomes of Hematopoietic Stem Cell Clones by PolyloxExpress Barcoding	89
Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer	87
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis	87
In vivo reprogramming of NG2 glia enables adult neurogenesis and functional recovery following spinal cord injury	86
Human Stem Cell-Derived Neurons Repair Circuits and Restore Neural Function	85
Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells	85
BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse	83
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo	83
A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells	83
Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function	82
Age-dependent alveolar epithelial plasticity orchestrates lung homeostasis and regeneration	81

Adult Neural Stem Cells Are Alerted by Systemic Inflammation through TNF-α Receptor Signaling	81
Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy	81
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging	80
Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium	80
Principles of signaling pathway modulation for enhancing human naive pluripotency induction	79