OOIR: Observatory of International Research

Papers

(The TQCC of Mucosal Immunology is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-12-01 to 2024-12-01.)

Article	Citations
Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation	245
Human gut-associated lymphoid tissues (GALT); diversity, structure, and function	206
The lung–gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes	195
The central role of the nasal microenvironment in the transmission, modulation, and clinical progression of SARS-CoV-2 infection	179
Systemic and mucosal IgA responses are variably induced in response to SARS-CoV-2 mRNA vaccination and are associated with protection against subsequent infection	175
The intestinal neuro-immune axis: crosstalk between neurons, immune cells, and microbes	175
Cellular and functional heterogeneity of the airway epithelium	145
Introduction to host microbiome symbiosis in health and disease	124
The impact of the lung environment on macrophage development, activation and function: diversity in the face of adversity	110
Tissue resident memory T cells in the respiratory tract	98
Dietary fiber metabolites regulate innate lymphoid cell responses	89
Neutrophils in respiratory viral infections	81
MAIT cells, guardians of skin and mucosa?	79
Crosstalk between the oral microbiota, mucosal immunity, and the epithelial barrier regulates oral mucosal disease pathogenesis	73
Long-term maintenance of lung resident memory T cells is mediated by persistent antigen	69
Host/microbiota interactions in health and diseases—Time for mucosal microbiology!	69
Microbiome-based interventions to modulate gut ecology and the immune system	63
Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation	63
Macrophage metabolic reprogramming during chronic lung disease	62
MAIT cell-directed therapy of Mycobacterium tuberculosis infection	61
Intestinal epithelial cell metabolism at the interface of microbial dysbiosis and tissue injury	60
Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells	57
A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation	56
Enteric neuroimmune interactions coordinate intestinal responses in health and disease	56
Granulocytes act as a niche for Mycobacterium tuberculosis growth	53

Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice	51
CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile	48
IL-22 receptor signaling in Paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-Salmonella immunity	48
IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils	47
Dealing with a mucosal viral pandemic: lessons from COVID-19 vaccines	45
Mucosal tissue regulatory T cells are integral in balancing immunity and tolerance at portals of antigen entry	43
Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages	43
Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial load and disease severity in human tuberculosis	41
Irg1/itaconate metabolic pathway is a crucial determinant of dendritic cells immune-priming function and contributes to resolute allergen-induced airway inflammation	41
Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism	40
Skin immunity: dissecting the complex biology of our body's outer barrier	39
Dendritic cell functions in the inductive and effector sites of intestinal immunity	38
The urothelium: a multi-faceted barrier against a harsh environment	38
The microbiome and host mucosal interactions in urinary tract diseases	38
Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling	38
Tissue-resident memory Th17 cells maintain stable fungal commensalism in the oral mucosa	37
The impact of biological sex on diseases of the urinary tract	37
Intestinal immune compartmentalization: implications of tissue specific determinants in health and disease	37
Mucosal immunology of the ocular surface	36
Genetic influences on viral-induced cytokine responses in the lung	36
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice	35
Mucosal immunity to poliovirus	35
Human mucosal tissue-resident memory T cells in health and disease	33
Tissue-specific immunity in helminth infections	33
Vitamin D receptor upregulates tight junction protein claudin-5 against colitis-associated tumorigenesis	32
Metabolic regulation by PPARγ is required for IL-33-mediated activation of ILC2s in lung and adipose tissue	32
NLRP6 modulates neutrophil homeostasis in bacterial pneumonia-derived sepsis	31
The neuropeptide VIP potentiates intestinal innate type 2 and type 3 immunity in response to feeding	30
PPARγ enhances ILC2 function during allergic airway inflammation via transcription regulation of ST2	30
Extrafollicular IgD+ B cells generate IgE antibody secreting cells in the nasal mucosa	29
αvβ8 integrin-expression by BATF3-dependent dendritic cells facilitates early IgA responses to Rotavirus	29
Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation	29
Enterocyte–innate lymphoid cell crosstalk drives early IFN-γ-mediated control of Cryptosporidium	29
Intestinal-derived ILCs migrating in lymph increase IFNγ production in response to Salmonella Typhimurium infection	29
Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates	28
Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance	28
Finding the sweet spot: glycosylation mediated regulation of intestinal inflammation	28
Murine astrovirus tropism for goblet cells and enterocytes facilitates an IFN-λ response in vivo and in enteroid cultures	27
A single-cell lung atlas of complement genes identifies the mesothelium and epithelium as prominent sources of extrahepatic complement proteins	26
Cannabinoids induce functional Tregs by promoting tolerogenic DCs via autophagy and metabolic reprograming	26
Role of the humoral immune response during COVID-19: guilty or not guilty?	26
Immunosurveillance of Candida albicans commensalism by the adaptive immune system	25
Intestinal epithelium-derived BATF3 promotes colitis-associated colon cancer through facilitating CXCL5-mediated neutrophils recruitment	25
Maternal natural killer cells at the intersection between reproduction and mucosal immunity	25
Heme oxygenase-1 inhibition promotes IFNγ- and NOS2-mediated control of Mycobacterium tuberculosis infection	25
Evolution and function of the epithelial cell-specific ER stress sensor IRE1β	25
Self and microbiota-derived epitopes induce CD4+ T cell anergy and conversion into CD4+Foxp3+ regulatory cells	25
Obeticholic acid ameliorates severity of Clostridioides difficile infection in high fat diet-induced obese mice	24
Dopaminergic signalling limits suppressive activity and gut homing of regulatory T cells upon intestinal inflammation	24
Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD	24

Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1	24
Enteric glial cells favor accumulation of anti-inflammatory macrophages during the resolution of muscularis inflammation	23
Clonotypic analysis of protective influenza M2e-specific lung resident Th17 memory cells reveals extensive functional diversity	23
Orally desensitized mast cells form a regulatory network with Treg cells for the control of food allergy	23
Circulating CD103+ γδ and CD8+ T cells are clonally shared with tissue-resident intraepithelial lymphocytes in celiac disease	22
Intestinal epithelium in early life	22
Interleukin-33 signaling exacerbates experimental infectious colitis by enhancing gut permeability and inhibiting protective Th17 immunity	22
The human memory T cell compartment changes across tissues of the female reproductive tract	22
Antibody secreting cells are critically dependent on integrin α4β7/MAdCAM-1 for intestinal recruitment and control of the microbiota during chronic colitis	22
Long-distance relationships - regulation of systemic host defense against infections by the gut microbiota	21
Influence of the early-life gut microbiota on the immune responses to an inhaled allergen	21
Bidirectional crosstalk between eosinophils and esophageal epithelial cells regulates inflammatory and remodeling processes	21
A vaccine combination of lipid nanoparticles and a cholera toxin adjuvant derivative greatly improves lung protection against influenza virus infection	21
Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques	21
Microbial regulation of intestinal motility provides resistance against helminth infection	21
Growth faltering regardless of chronic diarrhea is associated with mucosal immune dysfunction and microbial dysbiosis in the gut lumen	21
Epithelial production of elastase is increased in inflammatory bowel disease and causes mucosal inflammation	20
Plectin ensures intestinal epithelial integrity and protects colon against colitis	20
Regulation of tissue-resident memory T cells by the Microbiota	20
Tissue signals imprint Aiolos expression in ILC2s to modulate type 2 immunity	20
Characterisation of peri-implantation endometrial Treg and identification of an altered phenotype in recurrent pregnancy loss	20
Effects of helminths on the human immune response and the microbiome	20
Single-cell transcriptional profiling of murine conjunctival immune cells reveals distinct populations expressing homeostatic and regulatory genes	20
Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection	20
Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo	20
The IL-25-dependent tuft cell circuit driven by intestinal helminths requires macrophage migration inhibitory factor (MIF)	20
The fellowship of regulatory and tissue-resident memory cells	20
Trained immunity in type 2 immune responses	19
Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity	19
The role of retinoic acid in the production of immunoglobulin A	19
Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis	19
Bile acids modulate colonic MAdCAM-1 expression in a murine model of combined cholestasis and colitis	18
Adipocyte inflammation and pathogenesis of viral pneumonias: an overlooked contribution	18
MUC4 is overexpressed in idiopathic pulmonary fibrosis and collaborates with transforming growth factor β inducing fibrotic responses	18
The rise to power of the microbiome: power and sample size calculation for microbiome studies	18
Lung microbial-host interface through the lens of multi-omics	18
IL-33-induced neutrophilic inflammation and NETosis underlie rhinovirus-triggered exacerbations of asthma	17
A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4+ T cells and is defective in Crohn´s disease patients	17
CISH constrains the tuft–ILC2 circuit to set epithelial and immune tone	17
TGF-β production by eosinophils drives the expansion of peripherally induced neuropilin− RORγt+ regulatory T-cells during bacterial and allergen challenge	17