OOIR: Observatory of International Research

Papers

(The TQCC of Mucosal Immunology is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation	212
The lung–gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes	162
The central role of the nasal microenvironment in the transmission, modulation, and clinical progression of SARS-CoV-2 infection	162
Human gut-associated lymphoid tissues (GALT); diversity, structure, and function	153
Systemic and mucosal IgA responses are variably induced in response to SARS-CoV-2 mRNA vaccination and are associated with protection against subsequent infection	142
Animal and translational models of SARS-CoV-2 infection and COVID-19	142
The intestinal neuro-immune axis: crosstalk between neurons, immune cells, and microbes	131
Cellular and functional heterogeneity of the airway epithelium	112
Introduction to host microbiome symbiosis in health and disease	95
Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression	89
The impact of the lung environment on macrophage development, activation and function: diversity in the face of adversity	83
Dietary fiber metabolites regulate innate lymphoid cell responses	78
The NLRP6 inflammasome in health and disease	76
Tissue resident memory T cells in the respiratory tract	74
Neutrophils in respiratory viral infections	63
MAIT cells, guardians of skin and mucosa?	63
Long-term maintenance of lung resident memory T cells is mediated by persistent antigen	62
IL-17 production by tissue-resident MAIT cells is locally induced in children with pneumonia	60
MAIT cell-directed therapy of Mycobacterium tuberculosis infection	54
Crosstalk between the oral microbiota, mucosal immunity, and the epithelial barrier regulates oral mucosal disease pathogenesis	54
Macrophage metabolic reprogramming during chronic lung disease	54
A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation	53
The emerging roles of eosinophils in mucosal homeostasis	51
Targeted deletion of the TSLP receptor reveals cellular mechanisms that promote type 2 airway inflammation	51
Seasonal and pandemic influenza: 100 years of progress, still much to learn	51

Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells	50
Host/microbiota interactions in health and diseases—Time for mucosal microbiology!	50
Microbiome-based interventions to modulate gut ecology and the immune system	44
The role of miR-155 in cigarette smoke-induced pulmonary inflammation and COPD	44
Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice	44
Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation	44
CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile	42
Enteric neuroimmune interactions coordinate intestinal responses in health and disease	42
Granulocytes act as a niche for Mycobacterium tuberculosis growth	41
Dealing with a mucosal viral pandemic: lessons from COVID-19 vaccines	40
IL-22 receptor signaling in Paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-Salmonella immunity	39
Host responses to mucosal biofilms in the lung and gut	38
IL-17A both initiates, via IFNγ suppression, and limits the pulmonary type-2 immune response to nematode infection	38
Uric acid pathway activation during respiratory virus infection promotes Th2 immune response via innate cytokine production and ILC2 accumulation	38
Single-cell RNA sequencing analysis reveals alginate oligosaccharides preventing chemotherapy-induced mucositis	37
IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils	36
Intestinal epithelial cell metabolism at the interface of microbial dysbiosis and tissue injury	36
The development of colitis in Il10 mice is dependent on IL-22	36
Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism	36
The role of innate lymphoid cells in response to microbes at mucosal surfaces	35
Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages	35
Irg1/itaconate metabolic pathway is a crucial determinant of dendritic cells immune-priming function and contributes to resolute allergen-induced airway inflammation	34
Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial load and disease severity in human tuberculosis	34
Tissue-resident memory Th17 cells maintain stable fungal commensalism in the oral mucosa	34
γδ T cells compose a developmentally regulated intrauterine population and protect against vaginal candidiasis	33
The microbiome and host mucosal interactions in urinary tract diseases	32
Genetic influences on viral-induced cytokine responses in the lung	32
Dendritic cell functions in the inductive and effector sites of intestinal immunity	31
Mechanisms of activation of innate-like intraepithelial T lymphocytes	31
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice	31
Metabolic regulation by PPARγ is required for IL-33-mediated activation of ILC2s in lung and adipose tissue	31
Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation	30
Mucosal tissue regulatory T cells are integral in balancing immunity and tolerance at portals of antigen entry	30
Mucosal immunity to poliovirus	30
Selective deletion of MyD88 signaling in α-SMA positive cells ameliorates experimental intestinal fibrosis via post-transcriptional regulation	29
IL-33/ST2/IL-9/IL-9R signaling disrupts ocular surface barrier in allergic inflammation	29
Human mucosal tissue-resident memory T cells in health and disease	28
PPARγ enhances ILC2 function during allergic airway inflammation via transcription regulation of ST2	27
Intestinal-derived ILCs migrating in lymph increase IFNγ production in response to Salmonella Typhimurium infection	27
Resistance of children to Covid-19. How?	26
MicroRNA miR-155 is required for expansion of regulatory T cells to mediate robust pregnancy tolerance in mice	26
Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling	26
The impact of biological sex on diseases of the urinary tract	26
Intestinal immune compartmentalization: implications of tissue specific determinants in health and disease	26
Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity	25
Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance	25
Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation	25
Vitamin D receptor upregulates tight junction protein claudin-5 against colitis-associated tumorigenesis	25
αvβ8 integrin-expression by BATF3-dependent dendritic cells facilitates early IgA responses to Rotavirus	24
NLRP6 modulates neutrophil homeostasis in bacterial pneumonia-derived sepsis	24

Mucosal immunology of the ocular surface	24
Intestinal epithelium-derived BATF3 promotes colitis-associated colon cancer through facilitating CXCL5-mediated neutrophils recruitment	23
Remote allergen exposure elicits eosinophil infiltration into allergen nonexposed mucosal organs and primes for allergic inflammation	23
Microbial modulation of intestinal T helper cell responses and implications for disease and therapy	23
Sialylation and fucosylation modulate inflammasome-activating eIF2 Signaling and microbial translocation during HIV infection	23
Enterocyte–innate lymphoid cell crosstalk drives early IFN-γ-mediated control of Cryptosporidium	23
Murine astrovirus tropism for goblet cells and enterocytes facilitates an IFN-λ response in vivo and in enteroid cultures	23
Cannabinoids induce functional Tregs by promoting tolerogenic DCs via autophagy and metabolic reprograming	22
The urothelium: a multi-faceted barrier against a harsh environment	22
The neuropeptide VIP potentiates intestinal innate type 2 and type 3 immunity in response to feeding	22
Heme oxygenase-1 inhibition promotes IFNγ- and NOS2-mediated control of Mycobacterium tuberculosis infection	22
Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates	22
Orally desensitized mast cells form a regulatory network with Treg cells for the control of food allergy	22
LPS-binding IgG arrests actively motile Salmonella Typhimurium in gastrointestinal mucus	21
Extrafollicular IgD+ B cells generate IgE antibody secreting cells in the nasal mucosa	21
Obeticholic acid ameliorates severity of Clostridioides difficile infection in high fat diet-induced obese mice	21
Dopaminergic signalling limits suppressive activity and gut homing of regulatory T cells upon intestinal inflammation	20
Role of the humoral immune response during COVID-19: guilty or not guilty?	20
Protein kinase 2 (CK2) controls CD4+ T cell effector function in the pathogenesis of colitis	20
Lung IFNAR1hi TNFR2+ cDC2 promotes lung regulatory T cells induction and maintains lung mucosal tolerance at steady state	20
Tissue-specific immunity in helminth infections	20
Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD	19
A combination of LCPUFA ameliorates airway inflammation in asthmatic mice by promoting pro-resolving effects and reducing adverse effects of EPA	19
Evolution and function of the epithelial cell-specific ER stress sensor IRE1β	19
Antibiotic-induced microbiome perturbations are associated with significant alterations to colonic mucosal immunity in rhesus macaques	19
Exendin-4 restores airway mucus homeostasis through the GLP1R-PKA-PPARγ-FOXA2-phosphatase signaling	19
Self and microbiota-derived epitopes induce CD4+ T cell anergy and conversion into CD4+Foxp3+ regulatory cells	19
Maternal natural killer cells at the intersection between reproduction and mucosal immunity	19
Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo	19
A vaccine combination of lipid nanoparticles and a cholera toxin adjuvant derivative greatly improves lung protection against influenza virus infection	19
Interleukin-33 signaling exacerbates experimental infectious colitis by enhancing gut permeability and inhibiting protective Th17 immunity	18
Spatial proteomics revealed a CX3CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder	18
Growth faltering regardless of chronic diarrhea is associated with mucosal immune dysfunction and microbial dysbiosis in the gut lumen	18
Regulatory T cells control the dynamic and site-specific polarization of total CD4 T cells following Salmonella infection	18
Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity	18
Finding the sweet spot: glycosylation mediated regulation of intestinal inflammation	18
The human memory T cell compartment changes across tissues of the female reproductive tract	18
Plectin ensures intestinal epithelial integrity and protects colon against colitis	18
Skin immunity: dissecting the complex biology of our body's outer barrier	18
Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection	18