OOIR: Observatory of International Research

Papers

(The TQCC of Mucosal Immunology is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Mucosal-associated invariant T cells have therapeutic potential against ocular autoimmunity	237
Memorial for Nils Lycke	206
CD8 tissue-resident memory T cells bridge the gap between humoral and cell-mediated immunity	191
Editorial Board	178
Pro-inflammatory NK-like T cells are expanded in the blood and inflamed intestine in Crohn’s disease	141
Mitochondrial damage-associated molecular patterns: New perspectives for mitochondria and inflammatory bowel diseases	138
TIFA renders intestinal epithelial cells responsive to microbial ADP-heptose and drives colonic inflammation in mice	122
Impact of gut fungal and bacterial communities on the outcome of allogeneic hematopoietic cell transplantation	97
The bacterial lysate OM-85 engages Toll-like receptors 2 and 4 triggering an immunomodulatory gene signature in human myeloid cells	93
RIPK3 and caspase-8 interpret cytokine signals to regulate ILC3 survival in the gut	91
Circadian clock component PER2 negatively regulates CD4+ T cell IFN-γ production in ulcerative colitis	89
Distinct cell death pathways induced by granzymes collectively protect against intestinal Salmonella infection	89
Exposure to bacterial PAMPs before RSV infection exacerbates innate inflammation and disease via IL-1α and TNF-α	79
Dysregulated NOX1-NOS2 activity as hallmark of ileitis in mice	76
Neuromedin U promotes human type 2 immune responses	67
Molecular alterations in human milk in simulated maternal nasal mucosal infection with live attenuated influenza vaccination	67
Effects of helminths on the human immune response and the microbiome	61
Intestinal-derived ILCs migrating in lymph increase IFNγ production in response to Salmonella Typhimurium infection	61
Editorial Board	60
α4β7 expression guides B cells to front lines of defense in the gut	57
Heterogeneous Tfh cell populations that develop during enteric helminth infection predict the quality of type 2 protective response	54
Resistance is futile? Mucosal immune mechanisms in the context of microbial ecology and evolution	52
T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet	51
Interleukin-10 regulates goblet cell numbers through Notch signaling in the developing zebrafish intestine	50
Orally desensitized mast cells form a regulatory network with Treg cells for the control of food allergy	50

Moving beyond descriptive studies: harnessing metabolomics to elucidate the molecular mechanisms underpinning host-microbiome phenotypes	49
Response to Lauro and Zorzetti	47
Editorial Board	47
Editorial Board	44
Extracellular vesicles of Bacteroides uniformis induce M1 macrophage polarization and aggravate gut inflammation during weaning	43
Macrophages and glia are the dominant P2X7-expressing cell types in the gut nervous system—No evidence for the role of neuronal P2X7 receptors in colitis	41
The IL-25-dependent tuft cell circuit driven by intestinal helminths requires macrophage migration inhibitory factor (MIF)	40
Herpes stromal keratitis erodes the establishment of tissue-resident memory T cell pool in HSV-1 infected corneas	39
HOIL1 regulates group 2 innate lymphoid cell numbers and type 2 inflammation in the small intestine	38
S100A4 exerts robust mucosal adjuvant activity for co-administered antigens in mice	37
The fellowship of regulatory and tissue-resident memory cells	35
Mucosal immunity to poliovirus	35
Human mucosal tissue-resident memory T cells in health and disease	35
Skin immunity: dissecting the complex biology of our body's outer barrier	34
Impact of smoking on gut microbiota and short-chain fatty acids in human and mice: Implications for COPD	34
ATG16L1 protects from interferon-γ-induced cell death in the small intestinal crypt	33
Regulation of intestinal immunity by dietary fatty acids	33
Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation	31
Obesity-induced hyperglycemia impairs oral tolerance induction and aggravates food allergy	31
Regulation of tissue-resident memory T cells by the Microbiota	31
Editorial Board	31
Gut-homing and intestinal TIGITnegCD38+ memory T cells acquire an IL-12-induced, ex-Th17 pathogenic phenotype in a subgroup of Crohn’s disease patients with a severe disease course	30
Nonoptimal bacteria species induce neutrophil-driven inflammation and barrier disruption in the female genital tract	29
Respiratory tract Moraxella catarrhalis and Klebsiella pneumoniae can promote pathogenicity of myelin-reactive Th17 cells	29
High-fat diet-induced resistance to helminth infection via alternative induction of type 2 immunity	29
Acrylamide, an air pollutant, enhances allergen-induced eosinophilic lung inflammation via group 2 innate lymphoid cells	29
Comment on “Enterocyte–innate lymphoid cell crosstalk drives early IFNg-mediated control of Cryptosporidium”	29
Heat shock factor 1 drives regulatory T-cell induction to limit murine intestinal inflammation	29
CD200R1 promotes interleukin-17 production by group 3 innate lymphoid cells by enhancing signal transducer and activator of transcription 3 activation	28
Tr1 cell-mediated protection against autoimmune disease by intranasal administration of a fusion protein targeting cDC1 cells	28
A2Ar-dependent PD-1+ and TIGIT+ Treg cells have distinct homing requirements to suppress autoimmune uveitis in mice	28
Determination of Tr1 cell populations correlating with distinct activation states in acute IAV infection	26
Understanding the molecular mechanisms of anti-trafficking therapies and their clinical relevance in inflammatory bowel disease	25
B cell-mediated CD4 T-cell costimulation via CD86 exacerbates pro-inflammatory cytokine production during autoimmune intestinal inflammation	25
Activation of the SST-SSTR5 signaling pathway enhances corneal wound healing in diabetic mice	25
Translocating bacteria in SIV infection are not stochastic and preferentially express cytosine methyltransferases	25
Wnt/β-catenin maintains epithelial IL-33 in the colonic stem and progenitor cell niche and drives its induction in colitis	24
Formyl peptide receptor 1 mitigates colon inflammation and maintains mucosal homeostasis through the inhibition of CREB-C/EBPβ-S100a8 signaling	24
Tissue-resident natural killer cells derived from conventional natural killer cells are regulated by progesterone in the uterus	24
Atopic dermatitis and food allergy: More than sensitization	23
Interleukin-10 production by innate lymphoid cells restricts intestinal inflammation in mice	22
Spatially separated epithelium-associated and lamina propria neutrophils present distinct functional identities in the inflamed colon mucosa	22
Dietary influence and immune balance: Regulating CD4+ IEL responses and MHCII in the gut	22
Enteric glial cells favor accumulation of anti-inflammatory macrophages during the resolution of muscularis inflammation	22
Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity	22
Clonotypic analysis of protective influenza M2e-specific lung resident Th17 memory cells reveals extensive functional diversity	22
Interleukin-9 promotes mast cell progenitor proliferation and CCR2-dependent mast cell migration in allergic airway inflammation	21
mTOR-driven glycolysis governs induction of innate immune responses by bronchial epithelial cells exposed to the bacterial component flagellin	21
Intrapulmonary vaccination with delta-inulin adjuvant stimulates non-polarised chemotactic signalling and diverse cellular interaction	21
Interferon regulatory factor 6 (IRF6) determines intestinal epithelial cell development and immunity	21

Mucosal immunization with a delta-inulin adjuvanted recombinant spike vaccine elicits lung-resident immune memory and protects mice against SARS-CoV-2	21
TRPV1+ sensory nerves modulate corneal inflammation after epithelial abrasion via RAMP1 and SSTR5 signaling	21
TL1A priming induces a multi-cytokine Th9 cell phenotype that promotes robust allergic inflammation in murine models of asthma	21
A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4+ T cells and is defective in Crohn´s disease patients	21
MAIT cells, guardians of skin and mucosa?	20
LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms	20
Stress systems exacerbate the inflammatory response after corneal abrasion in sleep-deprived mice via the IL-17 signaling pathway	20
Loss of protein tyrosine phosphatase non-receptor type 2 reduces IL-4-driven alternative macrophage activation	20
Nur77 as a novel regulator of Paneth cell differentiation and function	20
Single-cell transcriptional profiling of murine conjunctival immune cells reveals distinct populations expressing homeostatic and regulatory genes	20
Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon	20
Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism	19
Lung microbial-host interface through the lens of multi-omics	19
Local complement activation and modulation in mucosal immunity	19
The urothelium: a multi-faceted barrier against a harsh environment	19
Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation	19
Entamoeba histolytica exploits the autophagy pathway in macrophages to trigger inflammation in disease pathogenesis	18
Sex-associated early-life viral innate immune response is transcriptionally associated with chromatin remodeling of type-I IFN-inducible genes	18
Neutrophils in respiratory viral infections	18
Role of the humoral immune response during COVID-19: guilty or not guilty?	18
CD52-targeted depletion by Alemtuzumab ameliorates allergic airway hyperreactivity and lung inflammation	18
Deciphering the therapeutic potential of Myeloid-Specific JAK2 inhibition in acute respiratory distress syndrome	17
Diabetes impairs IFNγ-dependent antibacterial defense in the lungs	17
Increased ocular plasma cells induce damaging α-synuclein+ microglia in autoimmune uveitis	17
Editorial Board	17
Cellular and functional heterogeneity of the airway epithelium	17
Tear duct M cells exacerbate allergic conjunctivitis by facilitating germinal-center reactions	16
Correction: Cellular and functional heterogeneity of the airway epithelium	16
Antibiotic-induced dysbiosis of the ocular microbiome affects corneal circadian rhythmic activity in mice	16
IL-18 is required for the TH1-adaptation of TREG cells and the selective suppression of TH17 responses in acute and chronic infections	16
Krüppel-like factor 2 controls IgA plasma cell compartmentalization and IgA responses	16
John Bienenstock Obituary	15
Editorial Board	15
Editorial Board	15
ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 cell development and protection against influenza virus infection	15
Guardians of the epithelium: macrophages protect against toxic fungal derivatives	15
Intestinal helminth infection transforms the CD4+ T cell composition of the skin	15
B-cell receptor physical properties affect relative IgG1 and IgE responses in mouse egg allergy	14
Adenosine restrains ILC2-driven allergic airway inflammation via A2A receptor	14
PD-1 signaling in neonates restrains CD8+ T cell function and protects against respiratory viral immunopathology	14
Vaccine protection by Cryptococcus neoformans Δsgl1 is mediated by γδ T cells via TLR2 signaling	14
Correction to: Comment on “ILC1 drive intestinal epithelial and matrix remodeling”	14
“Every cell is an immune cell; contributions of non-hematopoietic cells to anti-helminth immunity”	14
Long-distance relationships - regulation of systemic host defense against infections by the gut microbiota	14
Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation	14
Microbial regulation of intestinal motility provides resistance against helminth infection	14
Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates	14