Mucosal Immunology

Papers
(The median citation count of Mucosal Immunology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Editorial Board266
Editorial Board223
Memorial for Nils Lycke206
TL1A priming induces a multi-cytokine Th9 cell phenotype that promotes robust allergic inflammation in murine models of asthma147
Macrophages and glia are the dominant P2X7-expressing cell types in the gut nervous system—No evidence for the role of neuronal P2X7 receptors in colitis121
Dysregulated NOX1-NOS2 activity as hallmark of ileitis in mice114
Formyl peptide receptor 1 mitigates colon inflammation and maintains mucosal homeostasis through the inhibition of CREB-C/EBPβ-S100a8 signaling110
Mycobacterium tuberculosis preferentially infects specific macrophage subsets in primate granulomas during the early stages of tuberculosis107
Enteric glial cells favor accumulation of anti-inflammatory macrophages during the resolution of muscularis inflammation85
S100A4 exerts robust mucosal adjuvant activity for co-administered antigens in mice82
Role of the humoral immune response during COVID-19: guilty or not guilty?69
Respiratory tract Moraxella catarrhalis and Klebsiella pneumoniae can promote pathogenicity of myelin-reactive Th17 cells68
Tissue-resident natural killer cells derived from conventional natural killer cells are regulated by progesterone in the uterus53
Interleukin-10 production by innate lymphoid cells restricts intestinal inflammation in mice52
Chemokine receptor CCR9 suppresses the differentiation of CD4+CD8αα+ intraepithelial T cells in the gut48
Intestinal immunological events of acute and resolved SARS-CoV-2 infection in non-human primates48
“Every cell is an immune cell; contributions of non-hematopoietic cells to anti-helminth immunity”48
The IL-17A-neutrophil axis promotes epithelial cell IL-33 production during nematode lung migration47
Butyrate regulates neutrophil homeostasis and impairs early antimicrobial activity in the lung46
Microbial regulation of intestinal motility provides resistance against helminth infection46
Fibroblasts sense commensal-derived metabolites and regulate group 2 innate lymphoid cells-dependent defense in the stomach45
Differential effects of SARS-CoV-2-targeted infection of ATII, club cells, and macrophages on lung immunopathology and antiviral responses45
The neuroendocrine peptide catestatin promotes clearance of cutaneous Staphylococcus aureus through mast cell Mrgpr activation44
Epithelial barrier DUOX2 serves as early immune defense in intestinal pathogen control43
Dysregulated myeloid differentiation in colitis is induced by inflammatory osteoclasts in a TNFα-dependent manner42
Early postnatal eosinophil expansion associates with gut microbial-metabolic features and type 2 immunity in preterm infants42
Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling41
Inhaled Acinetobacter lwoffii exposure promotes lung PD-L1+ neutrophils and dampens viral-induced type 2 immunity39
Mucosal viral infection induces a regulatory T cell activation phenotype distinct from tissue residency in mouse and human tissues39
Immunometabolism and microbial metabolites at the gut barrier: Lessons for therapeutic intervention in inflammatory bowel disease37
NOD1 signaling regulates early tissue inflammation during helminth infection36
Conventional type I migratory CD103+ dendritic cells are required for corneal allograft survival35
Organismal mucosal immunology: A perspective through the eyes of game theory35
Mast cells disrupt the function of the esophageal epithelial barrier34
Microbial antigen in human milk: a natural vaccine?34
Peyer’s patch phagocytes acquire specific transcriptional programs that influence their maturation and activation profiles33
Gut segmented filamentous Bacteria impedes growth of B16F10 subcutaneous tumors via modulating T cell function33
HIV infection impairs the host response to Mycobacterium tuberculosis infection by altering surfactant protein D function in the human lung alveolar mucosa32
IgA facilitates the persistence of the mucosal pathogen Helicobacter pylori32
Impaired neutrophil migration underpins host susceptibility to infectious colitis32
Chronological maturation of the skin immune barrier is topographically different32
Airway macrophage glycolysis controls lung homeostasis and responses to aeroallergen32
PD-1 regulates ILC3-driven intestinal immunity and homeostasis31
Epithelial dysfunction is prevented by IL-22 treatment in a Citrobacter rodentium-induced colitis model that shares similarities with inflammatory bowel disease30
Clostridioides difficile toxin A and toxin B inhibit toxin-specific adaptive immune responses through glucosyltransferase-dependent activity30
Learning immunology from mothers and babies29
ADP-ribosylation factor 1 sustains regulatory T cell function and mucosal immune homeostasis in ulcerative colitis29
The gut-liver axis modulates intestinal immune homeostasis28
Lifelong partners: Gut microbiota-immune cell interactions from infancy to old age28
Single-cell analysis of human nasal mucosal IgE antibody secreting cells reveals a newly minted phenotype28
Airway epithelial cells as drivers of severe asthma pathogenesis28
A multi-omics microbiome signature is associated with the benefits of gastric bypass surgery and is differentiated from diet induced weight loss through 2 years of follow-up27
Editorial Board27
Single cell atlas of lung-resident innate lymphoid cells shows impact of age and dysbiosis on epigenetic and transcriptomic programming26
Role of IL-10 signaling in the circadian control of host response to influenza infection26
Pregnancy stages differentially impact maternal alveolar macrophages' function and immunity to SARS-CoV-2 infection25
Ileal mucus viscoelastic properties differ in Crohn’s disease25
Neuronal VIP wires the intestinal epithelial cell function25
Microbial remodeling of gut tryptophan metabolism and indole-3-lactate production regulate epithelial barrier repair and viral suppression in human and simian immunodeficiency virus infections24
Optimized hookworm-derived biologic, AIP-2NTQ48 restores mucosal tolerance and down-regulates colon cancer-associated gene expression in TNBS-induced colitis24
Metabolic regulation of macrophage-tissue interactions in the lung24
Triggering mouth-resident antiviral CD8+ T cells potentiates experimental periodontitis24
Migratory CD103+CD11b+ cDC2s in Peyer’s patches are critical for gut IgA responses following oral immunization23
TRIM33 prevents the exacerbation of allergic asthma by restricting the overactivation of alveolar macrophages23
Protective mucosal SARS-CoV-2 antibodies in the majority of the general population in the Netherlands23
A bifurcated role for c-Maf in Th2 and Tfh2 cells during helminth infection22
Protection against reinfection with Mycobacterium tuberculosis extends across heterologous Mtb lineages22
MAdCAM-1 co-stimulation combined with retinoic acid and TGF-β induces blood CD8+ T cells to adopt a gut CD101+ TRM phenotype22
Intestinal damage is required for the pro-inflammatory differentiation of commensal CBir1-specific T cells22
Breast milk delivery of an engineered dimeric IgA protects neonates against rotavirus21
Mucosal IL-36 is a defining feature of severe paediatric bronchiolitis20
Inflammation of the nasal mucosa is associated with susceptibility to experimental pneumococcal challenge in older adults20
Distal airway epithelial progenitors mediate TGF-β release to drive lung CD8+ TRM induction following mucosal BCG vaccination20
Dynamics of virus-specific CD8+ T cells in the human nasal cavity20
Notch-activated basophils support intestinal CD4+ T cell fate and function during Trichuris muris infection20
Seminal fluid expands the uterine gamma/delta T cell pool during early pregnancy in mice19
Molecular alterations in human milk in simulated maternal nasal mucosal infection with live attenuated influenza vaccination19
Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon19
Acrylamide, an air pollutant, enhances allergen-induced eosinophilic lung inflammation via group 2 innate lymphoid cells19
M2 macrophage-derived Apolipoprotein E promotes fibroblast MMPs expression via LRP1-ERK signaling in chronic rhinosinusitis with nasal polyps19
Moving beyond descriptive studies: harnessing metabolomics to elucidate the molecular mechanisms underpinning host-microbiome phenotypes19
4-1BBL on monocyte lineage cells rather than on classical dendritic cells drives CD8+ T cell accumulation in the respiratory tract and protects from severe respiratory influenza infection18
Neutrophil-chemoattractant CXCL5 increases lung barrier permeability in acute lung injury18
Systemic IgE promotes allergic rhinitis by licensing Th2-to-Tfh conversion and local IgE production18
MicroRNA-142 regulates gut associated lymphoid tissues and group 3 innate lymphoid cells17
Circadian clock component PER2 negatively regulates CD4+ T cell IFN-γ production in ulcerative colitis17
Deciphering the therapeutic potential of Myeloid-Specific JAK2 inhibition in acute respiratory distress syndrome17
Tofacitinib ameliorates Campylobacter-induced intestinal pathology by suppressing IFNγ producing ILCs and T cells17
The IL-25-dependent tuft cell circuit driven by intestinal helminths requires macrophage migration inhibitory factor (MIF)17
ETS translocation variant 5 (ETV5) promotes CD4+ T cell–mediated intestinal inflammation and fibrosis in inflammatory bowel diseases17
Neutrophil ADAM10 promotes migration and inflammation in ARDS by modulating adhesion and chemokine signaling16
From the gut to the lung: microbiota-associated metabolites as regulators of respiratory immunometabolism16
Trained ILC2 prevent IL-17-associated lung injury during helminth infection through a serotonin-dependent mechanism16
PD-1 signaling in neonates restrains CD8+ T cell function and protects against respiratory viral immunopathology15
Homeostatic and inflammatory functions of pulmonary GM-CSF15
Fibrinogen and lipopolysaccharide promote TLR4-dependent glucocorticoid resistance in airway mycosis-driven allergic airway disease15
Single-cell RNA sequencing reveals intrinsic and microbiota-associated sex differences in murine lung15
Necrotizing enterocolitis in premature infants—A defect in the brakes? Evidence from clinical and animal studies15
Integrin β7 sustains ileal humoral immunity and microbial biogeography during chronic TNF-driven ileitis15
Enteric glial adenosine 2B receptor signaling mediates persistent epithelial barrier dysfunction following acute DSS colitis15
A bacterial vesicle-based pneumococcal vaccine against influenza-mediated secondary Streptococcus pneumoniae pulmonary infection15
Long-distance relationships - regulation of systemic host defense against infections by the gut microbiota15
Editorial Board14
Sublingual allergen immunotherapy prevents house dust mite inhalant type 2 immunity through dendritic cell-mediated induction of Foxp3+ regulatory T cells14
Early life microbiota colonization programs nociceptor sensitivity by regulating NGF production in mast cells14
The C-type lectin receptor MINCLE interferes with eosinophil function and protective intestinal immunity in Strongyloides ratti-infected mice14
Distinct phenotypes and repertoires of bronchoalveolar and airway mucosal T cells in health and allergic asthma14
Shining the spotlight on urinary tract immunology14
Gut microbiota regulates intestinal goblet cell response and mucin production by influencing the TLR2-SPDEF axis in an enteric parasitic infection14
Hematopoietic MyD88 orchestrates the control of gut colonization by segmented filamentous bacteria14
The club cell circadian clock regulates temporal patterns in leukocyte trafficking in chronic allergic airways disease14
Opposing roles of resident and infiltrating immune cells in the defense against Legionella longbeachae via IL-18R/IFN-γ/ROS axis in mice14
Antigen-specific memory Th17 cells promote cross-protection against nontypeable Haemophilus influenzae after mild influenza A virus infection14
Beyond pathogen recognition: C-type lectin receptors in microbiota regulation14
Exploring the oral-gut linkage: Interrelationship between oral and systemic diseases14
CD38 and extracellular NAD+ regulate the development and maintenance of Hp vaccine‐induced CD4+ TRM in the gastric epithelium13
Viral destruction of the olfactory mucosa elicits immune residence, bone metaplasia, and long-term smell loss13
CD39 regulates P2RX7-mediated lung necrotic lesions in severe experimental tuberculosis13
Itaconate suppresses house dust mite-induced allergic airways disease and Th2 cell differentiation13
Short-course intranasal LAT9997 therapy limits post-influenza bacterial pneumonia by recalibrating lung immunity13
Spike-specific T cells are enriched in breastmilk following SARS-CoV-2 mRNA vaccination13
A pro-inflammatory gut mucosal cytokine response is associated with mild COVID-19 disease and superior induction of serum antibodies13
Repeated enema administration in rhesus macaques is not sufficient to promote bacterial dysbiosis or gastrointestinal dysfunction13
ILC3s mediate intestinal immune-epithelial interactions via TGF-β1 activation12
Single cell map of the adult female mouse urethra reveals epithelial and stromal macrophages with distinct functional identities12
Tissue-specific immunity in helminth infections12
Editorial Board12
Temporal Dissection of TGF-β signaling reveals differential impact during female reproductive mucosal CD8 resident memory T cell differentiation12
Innate immunity of the gut epithelium: Blowing in the WNT?12
Fibroblast-derived CSF1 maintains colonization of gut mucosal macrophage to resist bacterial infection12
Single-cell landscape reveals the epithelial cell-centric pro-inflammatory immune microenvironment in dry eye development12
The impact of biological sex on diseases of the urinary tract12
Cytokine networks driving eosinophil functional heterogeneity12
Sensory neuroimmune interactions at the barrier12
Epithelial regulation of microbiota-immune cell dynamics12
How the early life microbiome shapes immune programming in childhood asthma and allergies12
Autoantibodies induced by Mycoplasma pneumoniae infection underlie the severity of acute lung injury in children12
Sialidase fusion protein protects against influenza infection in a cigarette smoke-induced model of COPD12
Female sex hormones and the oral contraceptive pill modulate asthma severity through GLUT-111
Editorial Board11
IL-6 mediates defense against influenza virus by promoting protective antibody responses but not innate inflammation11
IL-5 antagonism reverses priming and activation of eosinophils in severe eosinophilic asthma11
Cytochrome P450 Cyp2s1 regulation of the intestinal metabolome and microbiome11
Long-term alterations in lung epithelial cells after EL-RSV infection exacerbate allergic responses through IL-1β-induced pathways11
Accumulation of mucosal and lymphoid hypo-functional granzyme K producing CD8+ effector memory T cells in idiopathic pulmonary fibrosis11
Editorial Board11
Immune crosstalk between respiratory and intestinal mucosal tissues in respiratory infections11
ILC2s govern imprinting of alveolar macrophage-mediated immune responses upon secondary helminth infection in the lung11
Dietary fiber promotes antigen presentation on intestinal epithelial cells and development of small intestinal CD4+CD8αα+ intraepithelial T cells11
Virus-specific resident memory T cell networks sustain immunity in human oral mucosa11
Heterogeneous Tfh cell populations that develop during enteric helminth infection predict the quality of type 2 protective response10
Neuromedin U promotes human type 2 immune responses10
Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation10
TIFA renders intestinal epithelial cells responsive to microbial ADP-heptose and drives colonic inflammation in mice10
Editorial Board10
IFN-γ- GranzymeB + Natural killer cells are induced by IV BCG vaccination and associated with protection against tuberculosis in rhesus macaques10
Exposure to bacterial PAMPs before RSV infection exacerbates innate inflammation and disease via IL-1α and TNF-α10
Interleukin-9 promotes mast cell progenitor proliferation and CCR2-dependent mast cell migration in allergic airway inflammation10
Wnt/β-catenin maintains epithelial IL-33 in the colonic stem and progenitor cell niche and drives its induction in colitis10
Obesity-induced hyperglycemia impairs oral tolerance induction and aggravates food allergy10
Wheat fiber-induced peripheral regulatory T-cells suppress development of colitis10
GPR15-GPR15L axis controls colon natural TCRαβ cells residency and enteroendocrine cell homeostasis to calibrate metabolism10
Impact of smoking on gut microbiota and short-chain fatty acids in human and mice: Implications for COPD10
T-cell immunity against influenza virus does not require Th1 or Th17 master regulator transcription factors10
Herpes stromal keratitis erodes the establishment of tissue-resident memory T cell pool in HSV-1 infected corneas10
Resistance is futile? Mucosal immune mechanisms in the context of microbial ecology and evolution10
CD8 tissue-resident memory T cells bridge the gap between humoral and cell-mediated immunity10
Colonic macrophage heterogeneity revealed by CD11c and CD16310
Iron-Dependent allergenicity of Alt a 1: A link between fungal nutritional immunity and allergic sensitization9
Antibiotic-induced dysbiosis of the ocular microbiome affects corneal circadian rhythmic activity in mice9
Interaction of microbiota, mucosal malignancies, and immunotherapy—Mechanistic insights9
Vaccine protection by Cryptococcus neoformans Δsgl1 is mediated by γδ T cells via TLR2 signaling9
Interferon regulatory factor 6 (IRF6) determines intestinal epithelial cell development and immunity9
Tear duct M cells exacerbate allergic conjunctivitis by facilitating germinal-center reactions9
Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation9
Combined plasma protein and memory T cell profiling discern IBD-patient-immunotypes related to intestinal disease and treatment outcomes9
IL-18 is required for the TH1-adaptation of TREG cells and the selective suppression of TH17 responses in acute and chronic infections9
Dysregulated MUC5B and MUC5AC impair epithelial barrier function and alter granulocyte frequency and activation in the lung and distal sites9
Allergic lung inflammation can be modulated by niacin and drives the development of glycolytic eosinophils9
Type-I interferons in Vulvovaginal Candidiasis: Mechanism of epithelial early defense and immune regulation against Candida albicans9
Inflammatory monocyte-derived amphiregulin mediates intestinal fibrosis in Crohn’s disease by activating PI3K/AKT9
Adaptive immune responses against Lachnospiraceae-derived flagellins and their role in inflammatory bowel disease9
Living on the edge: Mucus-associated microbes in the colon9
Indoleamine 2,3-dioxygenase 1 regulates cell permissivity to astrovirus infection8
Type I IFN signaling in the absence of IRGM1 promotes M. tuberculosis replication in immune cells by suppressing T cell responses8
Alveolar macrophages shape tuberculosis susceptibility by delaying protective immunity8
Ocular microbiota promotes pathological angiogenesis and inflammation in sterile injury-driven corneal neovascularization8
Correction to: Trained immunity in type 2 immune responses8
Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N18
MDA5-MAVS and interferon-lambda signaling in the intestinal epithelium limit murine astrovirus infection8
CCR2-driven monocyte recruitment is protective against radiotherapy-induced intestinal toxicity8
CTL lymph node entrapment drives lymphopenia in severe influenza infection8
Distinct olfactory mucosal macrophage populations mediate neuronal maintenance and pathogen defense8
Mechanotransduction-induced interplay between phospholamban and yes-activated protein induces smooth muscle cell hypertrophy8
Metabolic fitness of IgA+ plasma cells in the gut requires DOCK88
Pantothenic acid alleviates endometrial injury induced by vagotomy in mice8
Cannabidiol prevents mucosal HIV-1 transmission by targeting Langerhans cells, dendritic cells, macrophages and T-cells8
Specialized pro-resolving mediators regulate in vitro human airway epithelial resistance to Aspergillus fumigatus8
T follicular helper cells drive functionally distinct lymphoid and lung resident germinal centres and limit allergic airway disease8
IL-17-driven induction of Paneth cell antimicrobial functions protects the host from microbiota dysbiosis and inflammation in the ileum8
Eomes fate-labeling reveals a subset of Eomeslo NK cells that exhibits an ILC1-like phenotype7
MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T-cell responses7
Comparison of Omicron breakthrough infection versus monovalent SARS-CoV-2 intramuscular booster reveals differences in mucosal and systemic humoral immunity7
From germ-free to wild: modulating microbiome complexity to understand mucosal immunology7
Stem cell factor inhibition reduces Th2 inflammation and cellular infiltration in a mouse model of eosinophilic esophagitis7
PAD4 inhibition impacts immune responses in SARS-CoV-2 infection7
A reappraisal of IL-9 in inflammation and cancer7
MZB1-mediated IgA secretion suppresses the development and progression of colorectal cancer triggered by gut inflammation7
The clinical implications of bacterial pathogenesis and mucosal immunity in chronic urinary tract infection7
Corrigendum to “iNKT cell-neutrophil crosstalk promotes colorectal cancer pathogenesis” [Mucosal Immunol. 16(3) (2023) 326–3407
Viral-vectored boosting of OmcB- or CPAF-specific T-cell responses fail to enhance protection from Chlamydia muridarum in infection-immune mice and elicits a non-protective CD8-dominant response in na7
Human enteric defensin 5 protects intestinal barrier integrity via cell state–dependent P2Y11–FAK–Rac1 signaling7
Placental intervillous blood harbors NK cells with distinct tissue-resident characteristics7
Erratum to “Single cell transcriptional analysis of human adenoids identifies molecular features of airway microfold cells”. [Mucosal Immunol. 18(5) (2025) 1199–1217]7
Activation status of airway immune cells is a defining feature of severe asthma, regardless of fungal sensitisation7
Single cell transcriptional analysis of human adenoids identifies molecular features of airway microfold cells6
Parasite and host immune factors that impact the development of a mucosal vaccine for Cryptosporidium6
S1P/S1PR3 axis drives epithelial dysfunction and type 2 inflammation in chronic rhinosinusitis with nasal polyps6
Translocating bacteria in SIV infection are not stochastic and preferentially express cytosine methyltransferases6
The biliary tree: A new frontier in mucosal immunology?6
Microbiome-based interventions to modulate gut ecology and the immune system6
Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells6
CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages6
Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism6
The Nox2 NADPH oxidase regulates neutrophilic inflammation in the oral cavity6
A novel link driving immune cell-fibroblast interactions in intestinal fibrosis6
Indoor rewilding of laboratory mice recalibrates pulmonary mucosal immunity and mechanics6
STAT4 increases the phenotypic and functional heterogeneity of intestinal tissue-resident memory T cells6
Integrated human and mouse single-cell profiling reveals immune-stromal niche driving silicosis6
Innate immunity of the lungs in homeostasis and disease5
Regulation of intestinal immunity by dietary fatty acids5
Local complement activation and modulation in mucosal immunity5
Understanding the molecular mechanisms of anti-trafficking therapies and their clinical relevance in inflammatory bowel disease5
Leukotriene B4 regulates T cell recognition and control of MCMV in mucosal tissues5
Determination of Tr1 cell populations correlating with distinct activation states in acute IAV infection5
Mucosal immunization with a delta-inulin adjuvanted recombinant spike vaccine elicits lung-resident immune memory and protects mice against SARS-CoV-25
Diabetes impairs IFNγ-dependent antibacterial defense in the lungs5
Editorial Board5
Exposure to environmental microbiota may modulate gut microbial ecology and the immune system5
Lung microbial-host interface through the lens of multi-omics5
The urothelium: a multi-faceted barrier against a harsh environment5
High-fat diet-induced resistance to helminth infection via alternative induction of type 2 immunity5
TRPV1+ sensory nerves modulate corneal inflammation after epithelial abrasion via RAMP1 and SSTR5 signaling5
Expansion of genital Tregs reduces neutrophil influx and maintains mucosal barrier integrity during inflammatory bacteria challenge5
Single-cell profiling of BAL in preschool cystic fibrosis reveals macrophage dysregulation and ivacaftor-modified inflammatory programs in the early life lung5
Atopic dermatitis and food allergy: More than sensitization5
Mitochondrial damage-associated molecular patterns: New perspectives for mitochondria and inflammatory bowel diseases5
Activation of the SST-SSTR5 signaling pathway enhances corneal wound healing in diabetic mice5
RSV infection in neonatal mice and gastrointestinal microbiome alteration contribute to allergic predisposition5
Corrigendum to “Distinct cell death pathways induced by granzymes collectively protect against intestinal Salmonella infection” [Mucosal. Immun. 17 (2024) 1242–1255]5
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