OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Tissue Engineering and Regenerative Medicine is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Vascularization strategies in tissue engineering approaches for soft tissue repair	55
Using 3D‐bioprinting scaffold loaded with adipose‐derived stem cells to burns wound healing	39
Arabinoxylan/graphene‐oxide/nHAp‐NPs/PVA bionano composite scaffolds for fractured bone healing	37
Recent advances of hydrogel‐based biomaterials for intervertebral disc tissue treatment: A literature review	29
Gelatin methacryloyl as environment for chondrocytes and cell delivery to superficial cartilage defects	28
Upfront rational therapy in BRAF V600E mutated pediatric ameloblastoma promotes ad integrum mandibular regeneration	27
3D printed bioceramic scaffolds: Adjusting pore dimension is beneficial for mandibular bone defects repair	27
Myoblast 3D bioprinting to burst in vitro skeletal muscle differentiation	25
Validation of an implantable bioink using mechanical extraction of human skin cells: First steps to a 3D bioprinting treatment of deep second degree burn	24
LncRNA metastasis‐associated lung adenocarcinoma transcript‐1 promotes osteogenic differentiation of bone marrow stem cells and inhibits osteoclastic differentiation of Mø in osteoporosis via the miR‐	23
Osteoinductive and antimicrobial mechanisms of graphene‐based materials for enhancing bone tissue engineering	22
Effects of electrical stimulation on cytokine‐induced macrophage polarization	21
Evaluating the effects of vacuum on the microstructure and biocompatibility of bovine decellularized pericardium	21
A review of diabetic wound models—Novel insights into diabetic foot ulcer	21
Decellularization protocol‐dependent damage‐associated molecular patterns in rat uterus scaffolds differentially affect the immune response after transplantation	20
3D bioprinting of an electroactive and self‐healing polysaccharide hydrogels	19
Exosomes derived from miR‐129‐5p modified bone marrow mesenchymal stem cells represses ventricular remolding of mice with myocardial infarction	18
Electrical stimulation promotes the wound‐healing properties of diabetic human skin fibroblasts	18
Preparation and characterization of a soluble eggshell membrane/agarose composite scaffold with possible applications in cartilage regeneration	18
Decellularized spinal cord meninges extracellular matrix hydrogel that supports neurogenic differentiation and vascular structure formation	18
Uniform 40‐µm‐pore diameter precision templated scaffolds promote a pro‐healing host response by extracellular vesicle immune communication	17
Platelet‐rich plasma in the treatment of scars, to suggest or not to suggest? A systematic review and meta‐analysis	17
Prevascularized hydrogels with mature vascular networks promote the regeneration of critical‐size calvarial bone defects in vivo	17
Wnt5a/Platelet‐rich plasma synergistically inhibits IL‐1β‐induced inflammatory activity through NF‐κB signaling pathway and prevents cartilage damage and promotes meniscus regeneration	17
Intracerebral transplantation of autologous adipose‐derived stem cells for chronic ischemic stroke: A phase I study	16

Effects of the carbonate content in carbonate apatite on bone replacement	15
Exosomes derived from microRNA‐21 overexpressed adipose tissue‐derived mesenchymal stem cells alleviate spine osteoporosis in ankylosing spondylitis mice	15
Mechanical stimulation enhances development of scaffold‐free, 3D‐printed, engineered heart tissue grafts	15
A composite bilayer scaffold functionalized for osteochondral tissue regeneration in rat animal model	15
Preparation and evaluation of gellan gum hydrogel reinforced with silk fibers with enhanced mechanical and biological properties for cartilage tissue engineering	15
3D composite engineered using supercritical CO ₂ decellularized porcine cartilage scaffold, chondrocytes, and PRP: Role in articular cartilage regeneration	15
Individualized tissue‐engineered veins as vascular grafts: A proof of concept study in pig	14
Platelet lysate converts M (IFNγ+LPS) macrophages in CD206⁺TGF‐β⁺arginase⁺M2‐like macrophages that affect fibroblast activity and T lymphocyte migration	14
Co‐delivery of fibrin‐laminin hydrogel with mesenchymal stem cell spheroids supports skeletal muscle regeneration following trauma	14
GMP‐grade microcarrier and automated closed industrial scale cell production platform for culture of MSCs	14
Biomedical applications of silkworm ( Bombyx Mori ) proteins in regenerative medicine (a narrative review)	14
Antibacterial calcium phosphate cement with human periodontal ligament stem cell‐microbeads to enhance bone regeneration and combat infection	14
Human cardiac organoids to model COVID‐19 cytokine storm induced cardiac injuries	14
Engineering mechanobiology through organoids‐on‐chip: A strategy to boost therapeutics	14
Regulating effect of Circ_ATRNL1 on the promotion of SOX9 expression to promote chondrogenic differentiation of hAMSCs mediated by MiR‐145‐5p	13
Chemokine (C‐C motif) ligand 2‐enhanced adipogenesis and angiogenesis of human adipose‐derived stem cell and human umbilical vein endothelial cell co‐culture system in adipose tissue engineering	13
The intra‐articular injection of adipose‐derived stem cells decreases pain and reduces inflammation in knee osteoarthritis, with or without the addition of platelet‐rich plasma also improves functiona	13
Endocannabinoids increase human adipose stem cell differentiation and growth factor secretion in vitro	13
The role of long non‐coding RNAs and circular RNAs in bone regeneration: Modulating miRNAs function	13
LINC00662 facilitates osteosarcoma progression via sponging miR‐103a‐3p and regulating SIK2 expression	12
Addition of platelet‐rich plasma supports immune modulation and improved mechanical integrity in Alloderm mesh for ventral hernia repair in a rat model	12
Resveratrol benefits the lineage commitment of bone marrow mesenchymal stem cells into osteoblasts via miR‐320c by targeting Runx2	11
Histatin‐1 is a novel osteogenic factor that promotes bone cell adhesion, migration, and differentiation	11
Polyvinylidene fluoride/silk fibroin‐based bio‐piezoelectric nanofibrous scaffolds for biomedical application	11
Long‐term pre‐clinical evaluation of an injectable chitosan nanocellulose hydrogel with encapsulated adipose‐derived stem cells in an ovine model for IVD regeneration	11
In vitro maturation using an agarose matrix with incorporated extracellular matrix proteins improves porcine oocyte developmental competence by enhancing cytoplasmic maturation	11
Generation of neural progenitor cells from porcine‐induced pluripotent stem cells	11
Angiogenic CD34+CD146+ adipose‐derived stromal cells augment recovery of soft tissue after radiotherapy	11
Transplantation of human corneal limbal epithelial cell sheet harvested on synthesized carboxymethyl cellulose and dopamine in a limbal stem cell deficiency	10
Improvement of hepatocyte engraftment by co‐transplantation with pancreatic islets in hepatocyte transplantation	10
The regenerative effect of different growth factors and platelet lysate on meniscus cells and mesenchymal stromal cells and proof of concept with a functionalized meniscus implant	10
A phlorotannins‐loaded homogeneous acellular matrix film modulates post‐implantation inflammatory responses	10
Tissue engineering of corneal stroma via melt electrowriting	9
Tissue engineered axon‐based “living scaffolds” promote survival of spinal cord motor neurons following peripheral nerve repair	9
Efficient engineering of human auricular cartilage through mesenchymal stem cell chaperoning	9
The function and mechanism of the miR‐210‐3p/KRAS axis in bone marrow‐derived mesenchymal stem cell from patients with osteoporosis	9
Effects of low‐intensity pulsed ultrasound stimulation on cell seeded 3D hybrid scaffold as a novel strategy for meniscus regeneration: An in vitro study	9
3D printing of poly(butylene adipate‐co‐terephthalate) (PBAT)/niobium containing bioactive glasses (BAGNb) scaffolds: Characterization of composites, in vitro bioactivity, and in vivo bone repair	9
Exosomal‐ribosomal proteins‐driven heterogeneity of epicardial adipose tissue derived stem cells under ischemia for cardiac regeneration	9
Reverse engineering of an anatomically equivalent nerve conduit	9
Mesenchymal stem cells moderate experimental autoimmune uveitis by dynamic regulating Th17 and Breg cells response	9
Platelet‐rich plasma enhances mechanical strength of strattice in rat model of ventral hernia repair	9
Cartilage‐penetrating hyaluronic acid hydrogel preserves tissue content and reduces chondrocyte catabolism	9
Integrating nonlinear analysis and machine learning for human induced pluripotent stem cell‐based drug cardiotoxicity testing	9
Supercritical carbon dioxide decellularized porcine cartilage graft with PRP attenuated OA progression and regenerated articular cartilage in ACLT‐induced OA rats	8
Analysis of the regenerative capacity of human serum exosomes after a simple multistep separation from lipoproteins	8
Tissue engineered skeletal muscle model of rheumatoid arthritis using human primary skeletal muscle cells	8
Selective kidney targeting increases the efficacy of mesenchymal stromal/stem cells for alleviation of murine stenotic‐kidney senescence and damage	8
Recent advances in gene therapy for bone tissue engineering	8
Curcumin restores the engraftment capacity of aged hematopoietic stem cells and also reduces PD‐1 expression on cytotoxic T cells	8

Extruded poly (glycerol sebacate) and polyglycolic acid vascular graft forms a neoartery	8
Fabrication and evaluation of multifunctional agarose based electrospun scaffolds for cutaneous wound repairs	8
Regeneration of temporomandibular joint using in vitro human stem cells: A review	8
Recombinant factors for periodontal intrabony defects: A systematic review and network meta‐analysis of preclinical studies	8
Effect of glutaraldehyde‐crosslinked cartilage acellular matrix film on anti‐adhesion and nerve regeneration in a rat sciatic nerve injury model	8
Brain endothelial cells‐derived extracellular vesicles overexpressing ECRG4 inhibit glioma proliferation through suppressing inflammation and angiogenesis	8
Evolution of functional tissue engineering for tendon and ligament repair	7
COX‐2 inhibition does not alter wound healing outcomes of a volumetric muscle loss injury treated with a biologic scaffold	7
Production of homogenous size‐controlled human induced pluripotent stem cell aggregates using ring‐shaped culture vessel	7
Enhanced cellular migration and prolonged chondrogenic differentiation in decellularized cartilage scaffolds under dynamic culture conditions	7
The effect of resolvin D1 on bone regeneration in a rat calvarial defect model	7
Bone marrow mesenchymal stem cells with low dose bone morphogenetic protein 2 enhances scaffold‐based spinal fusion in a porcine model	7
Design and fabrication of polycaprolactone/gelatin composite scaffolds for diaphragmatic muscle reconstruction	7
Emerging tissue engineering strategies for the corneal regeneration	7
Nandrolone supplementation does not improve functional recovery in an aged animal model of volumetric muscle loss injury	6
Application of amniotic membranes in reconstructive surgery of internal organs—A systematic review and meta‐analysis	6
3D printing of heterogeneous microfibers with multi‐hollow structure via microfluidic spinning	6
Long‐term passages of human clonal mesenchymal stromal cells can alleviate the disease in the rat model of collagen‐induced arthritis resembling early passages of different heterogeneous cells	6
Uric acid released from poly(ε‐caprolactone) fibers as a treatment platform for spinal cord injury	6
Amniotic stromal stem cell‐loaded hydrogel repairs cardiac tissue in infarcted rat hearts via paracrine mediators	6
TGF‐β1 overexpressing human MSCs generated using gene editing show robust therapeutic potential for treating collagen‐induced arthritis	6
Fabrication of three dimensional bioactive Sr²⁺substituted apatite scaffolds by gel‐casting technique for hard tissue regeneration	6
Bioinspired hydrogel surfaces to augment corneal endothelial cell monolayer formation	6
Studies on oxygen availability and the creation of natural and artificial oxygen gradients in gelatin‐methacryloyl hydrogel 3D cell culture	6
Pro‐angiogenic potential of a functionalized hydrogel scaffold as a secretome delivery platform: An innovative strategy for cell homing‐based dental pulp tissue engineering	6
Effect of amniotic membrane and platelet‐rich fibrin membrane on bone healing post endodontic surgery: An ultrasonographic, randomized controlled study	6
Minimally invasive treatment of long bone non‐unions with bone marrow concentrate, demineralized bone matrix and platelet‐rich fibrin in 38 patients	6
Development of a decellularized porcine bone graft by supercritical carbon dioxide extraction technology for bone regeneration	6
Amniotic fluid allograft enhances the host response to ventral hernia repair using acellular dermal matrix	6
Role of enhancer of zeste homolog 2 in osteoclast formation and periodontitis development by downregulating microRNA‐101‐regulated VCAM‐1	6
A randomized controlled preclinical trial on 3 interposal temporomandibular joint disc implants: TEMPOJIMS—Phase 2	6
Poly(vinyl alcohol)‐methacrylate with CRGD peptide: A photocurable biocompatible hydrogel	6
An efficient and user‐friendly method for cytohistological analysis of organoids	6
Minocycline exhibits synergism with conditioned medium of bone marrow mesenchymal stem cells against ischemic stroke	6
Therapeutic approaches to activate the canonical Wnt pathway for bone regeneration	6
Development and evaluation of IL‐6 overexpressing mesenchymal stem cells (MSCs)	6
Preservation of microvascular integrity and immunomodulatory property of prevascularized human mesenchymal stem cell sheets	5
Zwitterionic keratin coating on silk‐Laponite fibrous membranes for guided bone regeneration	5
Treating mouse skull defects with 3D‐printed fatty acid and tricalcium phosphate implants	5
Extracellular matrix stiffness negatively affects axon elongation, growth cone area and F‐actin levels in a collagen type I 3D culture	5
Observation of a tight junction structure generated in LbL‐3D skin reconstructed by layer‐by‐layer cell coating technique	5
Effectiveness of a biodegradable 3D polylactic acid/poly(ɛ‐caprolactone)/hydroxyapatite scaffold loaded by differentiated osteogenic cells in a critical‐sized radius bone defect in rat	5
Monocytes contribute to a pro‐healing response in 40 μm diameter uniform‐pore, precision‐templated scaffolds	5
Platelet rich plasma concentration improves biologic mesh incorporation and decreases multinucleated giant cells in a dose dependent fashion	5
Targeting HIF‐α for robust prevascularization of human cardiac organoids	5
Accelerated vascularization of a novel collagen hydrogel dermal template	5
The inflammasome in biomaterial‐driven immunomodulation	5
Fabrication of functional rat pseudo‐islets after cryopreservation of pancreatic islets or dispersed islet cells	5
Hydrogel‐based 3D bioprints repair rat small intestine injuries and integrate into native intestinal tissue	5
In vivo effectiveness of hybrid membranes with osteogenic growth peptide for bone regeneration	5
A comparative evaluation of the effect of platelet rich fibrin matrix with and without peripheral blood mesenchymal stem cells on dental implant stability: A randomized controlled clinical trial	5
A comparative study of mesenchymal stem cells cultured as cell‐only aggregates and in encapsulated hydrogels	5
Recent scaffold‐based tissue engineering approaches in premature ovarian failure treatment	4
Clinical guideline for vascularized composite tissue cryopreservation	4
Clumps of mesenchymal stem cells/extracellular matrix complexes directly reconstruct the functional periodontal tissue in a rat periodontal defect model	4
Fabrication of BMP‐2‐peptide–Deferoxamine‐ and QK‐peptide‐functionalized nanoscaffolds and their application for bone defect treatment	4
Is percutaneous injection of bone marrow concentrate, demineralized bone matrix and PRF an alternative to curettage and bone grafting for treating aneurysmal bone cyst?	4
Recombinant Human Derived Growth and Differentiating Factors in treatment of periodontal intrabony defects: Systematic review and network meta‐analysis	4
TCP/PLGA composite scaffold loaded rapamycin in situ enhances lumbar fusion by regulating osteoblast and osteoclast activity	4
Biomaterials directed activation of a cryostable therapeutic secretome in induced pluripotent stem cell derived mesenchymal stromal cells	4
Effective decellularization of human skin tissue for regenerative medicine by supercritical carbon dioxide technique	4
Intraprostatic injection of exosomes isolated from adipose‐derived mesenchymal stem cells for the treatment of chronic non‐bacterial prostatitis	4
In‐depth analysis of the relationship between bovine intestinal organoids and enteroids based on morphology and transcriptome	4
Evidence that TD‐198946 enhances the chondrogenic potential of human synovium‐derived stem cells through the NOTCH3 signaling pathway	4
Porcine fibrin sealant combined with autologous chondrocytes successfully promotes full‐thickness cartilage regeneration in a rabbit model	4
Long‐term clinical and radiographic evaluation after maxillary sinus floor augmentation with octacalcium phosphate–collagen composite: A retrospective case series study	4
A combined cell and growth factor delivery for the repair of a critical size tibia defect using biodegradable hydrogel implants	4
Decellularized sturgeon cartilage extracellular matrix scaffold inhibits chondrocyte hypertrophy in vitro and in vivo	4
Vascular endothelial growth factor sustained delivery augmented cell therapy outcomes of cardiac progenitor cells for myocardial infarction	4
Magneto‐conducting multifunctional Janus microbots for intracellular delivery of biomolecules	4
Three‐dimensional wet electrospun scaffold system for the differentiation of adipose‐derived mesenchymal stem cells to islet‐like clusters	4