OOIR: Observatory of International Research

Papers

(The median citation count of Biomicrofluidics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Lab-on-a-disk extraction of PBMC and metered plasma from whole blood: An advanced event-triggered valving strategy	50
I-LIFT (image-based laser-induced forward transfer) platform for manipulating encoded microparticles	50
Recent advances in label-free optical, electrochemical, and electronic biosensors for glioma biomarkers	36
Epithelial and mesenchymal phenotypes determine the dynamics of circulating breast tumor cells in microfluidic capillaries under chemotherapy-induced stress	29
Thermal bubble single-cell printing chip: High-throughput, wide-field, and efficient	24
Trajectory analysis of Bacillus subtilis in micro-droplets	24
Microflows in two-generation alveolar cells at an acinar bifurcation	24
Dynamic cellular responses to gravitational forces: Exploring the impact on white blood cell(s)	24
Nanogap traps for passive bacteria concentration and single-point confocal Raman spectroscopy	23
High-throughput deterministic pairing and coculturing of single cells in a microwell array using combined hydrodynamic and recirculation flow captures	23
Design of a flexing organ-chip to model in situ loading of the intervertebral disc	22
Long-term cultured microvascular networks on chip for tumor vascularization research and drug testing	19
Robotic automation of droplet microfluidics	18
Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models in vitro	18
Potential of the acoustic micromanipulation technologies for biomedical research	18
Liver-on-a-chip: Considerations, advances, and beyond	17
Preface to the Special Topic: Microfluidics, Circulating Biomarkers and Cancer	17
Non-invasive acquisition of mechanical properties of cells via passive microfluidic mechanisms: A review	16
Recent advances in microfluidic-based spectroscopic approaches for pathogen detection	16
Artificial intelligence-driven electrochemical immunosensing biochips in multi-component detection	16
Microfluidic sweat patch based on capillary force and evaporation pump for real-time continuous sweat analysis	15
The enhancement of DNA fragmentation in a bench top ultrasonic water bath with needle-induced air bubbles: Simulation and experimental investigation	14
pH effects on capture efficiency and deposition patterns in sessile droplet immunoassays: An XDLVO analysis	14
Microfluidic-to-macrofluidic: A simple in vitro model of atherosclerosis induced by fluidic stimulation	14
Simultaneous high-throughput particle-bacteria separation and solution exchange via in-plane and out-of-plane parallelization of microfluidic centrifuges	14

A brief overview of passive microvalves in microfluidics: Mechanism, manufacturing, and applications	14
Improved acoustic holograms using simulated annealing	13
Investigating the effect of phospholipids on droplet formation and surface property evolution in microfluidic devices for droplet interface bilayer (DIB) formation	13
A microfluidic sucrose gap platform using trilaminar flow with on-chip switching and novel calibration: Challenges and limitations	13
Microfluidic supercritical CO2 applications: Solvent extraction, nanoparticle synthesis, and chemical reaction	13
Digital microfluidics methods for nucleic acid detection: A mini review	13
Lateral force separation of biopolymers using an atomic force microscope	12
Soluto-thermal Marangoni convection in stationary micro-bioreactors on heated substrates: Tool for in vitro diagnosis of PSA	11
Application and prospect of microfluidic devices for rapid assay of cell activities in the tumor microenvironment	11
What is the future of electrical impedance spectroscopy in flow cytometry?	11
Mechanically mediated cargo delivery to cells using microfluidic devices	11
Laser induced graphanized microfluidic devices	10
Cell pairing for biological analysis in microfluidic devices	10
Drop-to-drop liquid–liquid extraction of DNA in an electrowetting-on-dielectric digital microfluidics	10
Continuous separation of bacterial cells from large debris using a spiral microfluidic device	10
Biphasic flow dynamics and polarized mass transportation in branched hepatic sinusoids	10
Parallel study of transient dosing of antibiotics in a microfluidic device	10
On-chip dielectrophoretic device for cancer cell manipulation: A numerical and artificial neural network study	10
A miniaturized culture platform for control of the metabolic environment	9
Effect of vimentin on cell migration in collagen-coated microchannels: A mimetic physiological confined environment	9
Manually pressurized droplet digital PCR chip for rapid SARS-CoV-2 diagnostics	9
Brain organoid-on-a-chip: A next-generation human brain avatar for recapitulating human brain physiology and pathology	8
Micromixing within microfluidic devices: Fundamentals, design, and fabrication	8
High-Q WGM microcavity-based optofluidic sensor technologies for biological analysis	8
Air microfluidics-enabled soft robotic transtibial prosthesis socket liner toward dynamic management of residual limb contact pressure and volume fluctuation	8
Low-cost and convenient fabrication of polymer micro/nanopores with the needle punching process and their applications in nanofluidic sensing	8
Design automation for deterministic lateral displacement by leveraging deep Q-network	8
Confinement effect on the microcapillary flow and shape of red blood cells	8
Hepatic spheroid-on-a-chip: Fabrication and characterization of a spheroid-based in vitro model of the human liver for drug screening applications	8
Recent advances in the understanding of alveolar flow	8
Microfluidics-enabled functional 3D printing	8
Recent advances in microfluidic-based cancer immunotherapy-on-a-chip strategies	7
Organ-specific vasculature-on-a-chip systems	7
An in vitro multi-organ microphysiological system (MPS) to investigate the gut-to-brain translocation of neurotoxins	7
Perspective on fluorescence cell imaging with ionophore-based ion-selective nano-optodes	7
Microfluidic synthesis as a new route to produce novel functional materials	7
Engineering porous membranes mimicking in vivo basement membrane for organ-on-chips applications	7
Addressable microfluidics technology for non-sacrificial analysis of biomaterial implants in vivo	7
Mimicking blood and lymphatic vasculatures using microfluidic systems	6
Wall shear gradient dependent thrombosis studied in blood-on-a-chip with stenotic, branched, and valvular constructions	6
Organoid-on-a-chip: Current challenges, trends, and future scope toward medicine	6
Referee acknowledgment for 2021	6
From specialization to broad adoption: Key trends in droplet microfluidic innovations enhancing accessibility to non-experts	6
Developing a piezoresistive sensor based bionic neurological intraoperative monitoring system for spine surgery skill training	6
Faradaic-free electrokinetic nucleic acid amplification (E-NAAMP) using localized on-chip high frequency Joule heating	6
The interaction of vortical flows with red cells in venous valve mimics	6
A high-throughput flowless microfluidic single and multi-solute concentration gradient generator: Design and parametric study	6
Naturally derived colloidal rods in microfluidic flows	5
Microfluidic system for near-patient extraction and detection of miR-122 microRNA biomarker for drug-induced liver injury diagnostics	5
Titrating chimeric antigen receptors on CAR T cells enabled by a microfluidic-based dosage-controlled intracellular mRNA delivery platform	5

Review on bile dynamics and microfluidic-based component detection: Advancing the understanding of bilestone pathogenesis in the biliary tract	5
Paper-based analytical devices for point-of-care blood tests	5
Inertial focusing of particles and cells in the microfluidic labyrinth device: Role of sharp turns	5
Dean vortex-enhanced blood plasma separation in self-driven spiral microchannel flow with cross-flow microfilters	5
Inertial microfluidics in contraction–expansion microchannels: A review	5
Microfluidic wearable electrochemical sweat sensors for health monitoring	5
Nano/microfluidic device for high-throughput passive trapping of nanoparticles	5
Microneedle arrays integrated with microfluidic systems: Emerging applications and fluid flow modeling	5
Tunable motile sperm separation based on sperm persistence in migrating through shear barriers	5
Phenotyping of rare circulating cells in the blood of non-metastatic breast cancer patients using microfluidic Labyrinth technology	5
Artificial blood for therapeutic and laboratory usage: Where do we stand?	5
Hematocrit skewness along sequential bifurcations within a microfluidic network induces significant changes in downstream red blood cell partitioning	5
Microfluidic technology for multiple single-cell capture	5
Visualizing liquid distribution across hyphal networks with cellular resolution	5
Extracellular vesicle and lipoprotein diagnostics (ExoLP-Dx) with membrane sensor: A robust microfluidic platform to overcome heterogeneity	5
Ultraviolet control of bacterial biofilms in microfluidic chips	5
Nanoextraction based on surface nanodroplets for chemical preconcentration and determination	5
Microfluidic technologies for advanced antimicrobial susceptibility testing	5
Toward droplets displaying life-like interaction behaviors	5
Toward embryo cryopreservation-on-a-chip: A standalone microfluidic platform for gradual loading of cryoprotectants to minimize cryoinjuries	5
Universal correlation for the critical diameter of deterministic lateral displacement devices with polygonal posts	5
Photo-addressable microwell devices for rapid functional screening and isolation of pathogen inhibitors from bacterial strain libraries	4
Directed colloidal assembly and banding via DC electrokinetics	4
Scalable large-area mesh-structured microfluidic gradient generator for drug testing applications	4
Spheroids formation in large drops suspended in superhydrophobic paper cones	4
Microfluidic pumps for cell sorting	4
The mechanism of biofilm detachment in porous medium under flow field	4
Microfluidic detection of viruses for human health	4
Standardizing characterization of membrane active peptides with microfluidics	4
Giardia purification from fecal samples using rigid spiral inertial microfluidics	4
Microbial stir bars: Light-activated rotation of tethered bacterial cells to enhance mixing in stagnant fluids	4
Molecular diffusion analysis of dynamic blood flow and plasma separation driven by self-powered microfluidic devices	4
A simple acoustofluidic device for on-chip fabrication of PLGA nanoparticles	4
The centrifugal viscometer	4
Acoustohydrodynamic micromixers: Basic mixing principles, programmable mixing prospectives, and biomedical applications	4
In situ 3D polymerization (IS-3DP): Implementing an aqueous two-phase system for the formation of 3D objects inside a microfluidic channel	4
Microfluidic cell sorter sample preparation for genomic assays	3
Microfluidics-based patient-derived disease detection tool for deep learning-assisted precision medicine	3
A perspective on computer vision in biosensing	3
Water filling of microcavities	3
A bionic mimosa soft robot based on a multi-responsive PNIPAM-PEGDA hydrogel composition	3
All polymer microfluidic chips—A fixed target sample delivery workhorse for serial crystallography	3
Advances in point-of-care genetic testing for personalized medicine applications	3
Integrating an aerosolized drug delivery device with conventional static cultures and a dynamic airway barrier microphysiological system	3
A novel air microfluidics-enabled soft robotic sleeve: Toward realizing innovative lymphedema treatment	3
The role of acoustofluidics and microbubble dynamics for therapeutic applications and drug delivery	3
Microfluidic production of monodisperse emulsions for cosmetics	3
Surface-dominant micro/nanofluidics for efficient green energy conversion	3
Dual-wavelength volumetric stereolithography of multilevel microfluidic devices	3
Harnessing the power of Microscale AcoustoFluidics: A perspective based on BAW cancer diagnostics	3
Rosette-induced separation of T cells by acoustophoresis	3
Automatic feedback control by image processing for mixing solutions in a microfluidic device	3
Microfluidic devices fitted with “flowver” paper pumps generate steady, tunable gradients for extended observation of chemotactic cell migration	3
A traveling surface acoustic wave-based micropiezoactuator: A tool for additive- and label-free cell lysis	3
Microfluidic-assisted fiber production: Potentials, limitations, and prospects	2
Low-cost and cleanroom-free prototyping of microfluidic and electrochemical biosensors: Techniques in fabrication and bioconjugation	2
Deep learning assisted mechanotyping of individual cells through repeated deformations and relaxations in undulating channels	2
Micropatterning of functional lipid bilayer assays for quantitative bioanalysis	2
Efficient single-cell oxygen consumption rate characterization based on frequency domain fluorescence lifetime imaging microscopy measurement and microfluidic platform	2
Role of microfluidics in accelerating new space missions	2
Vascularized platforms for investigating cell communication via extracellular vesicles	2
A high throughput blood–brain barrier model incorporating shear stress with improved predictive power for drug discovery	2
Emerging trends in functional molecularly imprinted polymers for electrochemical detection of biomarkers	2
RapidQ: A reader-free microfluidic platform for the quantitation of antibodies against the SARS-CoV-2 spike protein	2
A passive and programmable 3D paper-based microfluidic pump for variable flow microfluidic applications	2
Recent advances in portable devices for environmental monitoring applications	2
Microfluidics based bioimaging with cost-efficient fabrication of multi-level micrometer-sized trenches	2
Droplet-based valveless microfluidic system for phage-display screening against spheroids	2
Nucleation kinetics of calcium oxalate monohydrate as a function of pH, magnesium, and osteopontin concentration quantified with droplet microfluidics	2
Strain-induced self-rolled-up microtubes for multifunctional on-chip microfluidic applications	2
Engineering advancements in microfluidic systems for enhanced mixing at low Reynolds numbers	2
3D collagen microchamber arrays for combined chemotherapy effect evaluation on cancer cell numbers and migration	2
Phototactic microswimmers in pulsatile flow: Toward a novel harvesting method	2
Microfluidics for the biological analysis of atmospheric ice-nucleating particles: Perspectives and challenges	2
A flexible strategy to fabricate trumpet-shaped porous PDMS membranes for organ-on-chip application	2
Interpretation of cell mechanical experiments in microfluidic systems depend on the choice of cellular shape descriptors	2
A simple guideline for designing droplet microfluidic chips to achieve an improved single (bio)particle encapsulation rate using a stratified flow-assisted particle ordering method	2
Scaling microfluidic throughput with flow-balanced manifolds to simply control devices with multiple inlets and outlets	2