Translational Research

Article	Citations
Information for Readers	146
Contents	126
Polymerized human hemoglobin with low and high oxygen affinity in trauma models	79
Author Guidelines	75
Contents	63
Information for Readers	62
Information for Readers	61
Editorial Advisory Board	59
Clonal hematopoiesis and bone marrow inflammation	53
Deep next-generation proteomics and network analysis reveal systemic and tissue-specific patterns in Fabry disease	51
Multi-Omics Analysis Links Mitochondrial-Related Genes to Idiopathic Pulmonary Fibrosis and In Vivo Transcriptome Validation	45
Single-cell RNA sequencing reveals the MIF/ACKR3 receptor-ligand interaction between neutrophils and nucleus pulposus cells in intervertebral disc degeneration	45
Targeting mutant dicer tumorigenesis in pleuropulmonary blastoma via inhibition of RNA polymerase I	44
Kv1.3 expression on CD4 (+) T cells promotes interleukin-17A-associated airway inflammation and airway remodeling in asthma	42
A modified porous silicon microparticle potentiates protective systemic and mucosal immunity for SARS-CoV-2 subunit vaccine	40
An optimal promoter regulating cytokine transgene expression is crucial for safe and effective oncolytic virus immunotherapy	38
Unveiling the molecular mechanisms of hemorrhagic shock and acute lung injury: An integrative RNA-Seq and network analysis	38
The biomimetic extracellular matrix: a therapeutic tool for breast cancer research	37
Masthead	36
Reversal of cisplatin resistance in oral squamous cell carcinoma by piperlongumine loaded smart nanoparticles through inhibition of Hippo-YAP signaling pathway	35
Cardiac-specific overexpression of CREM-IbΔC-X via CRISPR/Cas9 in mice presents a new model of atrial cardiomyopathy with spontaneous atrial fibrillation	35
Masthead	34
GPX4 transcriptionally promotes liver cancer metastasis via GRHL3/PTEN/PI3K/AKT axis	34
Canagliflozin inhibits hedgehog interacting protein (Hhip) induction of tubulopathy in diabetic Akita mice	34
Contents	33

Abundance of dopamine and its receptors in the brain and adipose tissue following diet-induced obesity or caloric restriction	32
Unlocking the future of cancer diagnosis – promises and challenges of ctDNA-based liquid biopsies in non-small cell lung cancer	32
ASH2L-mediated H3K4me3 drives diabetic nephropathy through HIPK2 and Notch1 pathway	31
Human lung organoids as a model for respiratory virus replication and countermeasure performance in human hosts	30
Heterogeneous nuclear ribonucleoprotein F deficiency in mouse podocyte promotes podocytopathy mediated by methyltransferase-like 14 nuclear translocation resulting in Sirtuin 1 gene inhibition	30
Understanding the adipose tissue acetylome in obesity and insulin resistance	30
Kidney organoids: a pioneering model for kidney diseases	30
Masthead	29
Information for Readers	29
Editorial Advisory Board	29
Editorial Advisory Board	28
Reassessment of mitochondrial cyclophilin D as a target for improving cardiac arrest outcomes in the era of therapeutic hypothermia	28
Editorial Advisory Board	27
Information for Readers	27
Contents	27
Contents	27
Masthead	26
Editorial Advisory Board	26
Angiogenic and reparative potency of a human cardiac CD90− mesenchymal subpopulation in heart ischemic model	25
Editorial Advisory Board	25
Contents	25
Inhibition of PI3K/C/EBPβ axis in tolerogenic bone marrow-derived dendritic cells of NOD mice promotes Th17 differentiation and diabetes development	24
Contents	24
Editorial Advisory Board	23
FAK-TRIM25 promotes HSC activation and glycolysis by inhibiting c-Myc ubiquitination via FBXW7	23
Inhibition of gasdermin D palmitoylation by disulfiram is crucial for the treatment of myocardial infarction	23
STIM1 deletion in regulatory T cells restores redox balance and protects against hypertension-induced cardiovascular complications	23
Author Guidelines	23
PHGDH alleviates DKD by regulating YB1/SLC7A11-mediated ferroptosis in podocytes	23
Interferon pathway lupus risk alleles modulate risk of death from acute COVID-19	23
Masthead	22
Claudin-1 mediates progression by regulating EMT through AMPK/TGF-β signaling in head and neck squamous cell carcinoma	22
Cardiopulmonary bypass with deep hypothermic circulatory arrest results in organ-specific transcriptomic responses in pediatric swine	22
Contents	22
Information for Readers	22
Information for Readers	22
Early growth response protein 2 promotes partial epithelial-mesenchymal transition by phosphorylating Smad3 during renal fibrosis	22
Overexpressing glyoxalase 1 attenuates acute hyperglycemia–exacerbated neurological deficits of ischemic stroke in mice	21
Calcium-sensing receptor activator cinacalcet for treatment of cyclic nucleotide-mediated secretory diarrheas	21
Multi-dimensional metabolomic profiling reveals dysregulated ornithine metabolism hallmarks associated with a severe acute pancreatitis phenotype	21
Author Guidelines	20
Contents	20
In Vivo Cardiac-specific Expression of Adenylyl Cyclase 4 Gene Protects against Klotho Deficiency-induced Heart Failure	20
Contents	20
Masthead	20
Author Guidelines	20
Rabies virus glycoprotein 29 (RVG29) promotes CAR-T immunotherapy for glioma	20
Contents	19
Depleted hexokinase1 and lack of AMPKα activation favor OXPHOS-dependent energetics in retinoblastoma tumors	19
Discovery of CC-99677, a selective targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune disorders	19

Computational drug repositioning of clopidogrel as a novel therapeutic option for focal segmental glomerulosclerosis	19
Corrected cerebral blood flow and reduced cerebral inflammation in berk sickle mice with higher fetal hemoglobin	19
Repurposing calcium-sensing receptor activator drug cinacalcet for ADPKD treatment	19
Effectiveness of circulating tumor cells and circulating tumor DNA in peritoneal lavage fluid for predicting metachronous peritoneal metastasis of gastric cancer	19
Spatial proteomics and transcriptomics of the maternal-fetal interface in placenta accreta spectrum	19
Author Guidelines	18
Masthead	18
Inhibiting CCR3 expands cancer stem cells via c-Myc–NTSR1 axis and associates with tumor innervation features	18
Contents	18
Information for Readers	17
Importance of multiple endocrine cell types in islet organoids for type 1 diabetes treatment	17
Contents	17
Breastfeeding by chikungunya virus-infected dams confers resistance to challenge in the offspring	17
Regulation of nutrient and electrolyte absorption in human organoid-derived intestinal epithelial cell monolayers	17
Information for Readers	17
Early vascular aging in chronic kidney disease: focus on microvascular maintenance, senescence signature and potential therapeutics	16
Contents	16
RAS protein activator-like 2 (RASAL2) initiates peritubular capillary rarefaction in hypoxic renal interstitial fibrosis	16
Author Guidelines	16
Risk factors for clonal hematopoiesis of indeterminate potential and mosaic chromosomal alterations	16
Contents	16
Emerging evidence on the role of clonal hematopoiesis of indeterminate potential in chronic kidney disease	16
A dual action small molecule enhances azoles and overcomes resistance through co-targeting Pdr5 and Vma1	16
A human vascularized microtumor model of patient-derived colorectal cancer recapitulates clinical disease	16
Editorial Advisory Board	16
Intranasal application of adeno-associated viruses: a systematic review	16
TSG-6 Exacerbates Myocardial Ischemia-Reperfusion Injury by Activating NLRP3 Inflammasome and Regulating Macrophage Polarization	16
Contents	16
Contents	15
Information for Readers	15
A CD36 transmembrane domain peptide interrupts CD36 interactions with membrane partners on macrophages and inhibits atherogenic functions	15
Platelet bound B cells and their role in SSc: Implications for disease subtypes and clinical outcomes	15
Contents	15
Epigenetically targeting PRMT5 promotes antitumor immunity by inducing endogenous retroviruses expression and triggering viral mimicry response	15
Contents	15
SERPINA5 may promote the development of preeclampsia by disruption of the uPA/uPAR pathway	14
Crosstalk between GABAA receptors in astrocytes and neurons triggered by general anesthetic drugs	14
Novel MSH2 and TSC2 variants in a Chinese family with Lynch syndrome and their synergistic impact in urothelial carcinoma	14
Genome-wide characterization of extrachromosomal circular DNA in SLE and functional analysis reveal their association with apoptosis	14
Sex-related differences in SIRT3-mediated mitochondrial dynamics in renal ischemia/reperfusion injury	13
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression	13
Bronchoscopy-guided synergistic pulsed irreversible electroporation ablation as a novel intervention therapy for lung lesions: A pilot study in a preclinical model	13
Contents	13
DUSP5 deficiency suppresses the progression of acute kidney injury by enhancing autophagy through AMPK/ULK1 pathway	13
Trehalose-driven TFEB Activation Reprograms Immunosuppressive Macrophages in Glioblastoma	13
Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration	13
Author Guidelines	13
Trimethylamine N-oxide exacerbates myocardial ischemia-reperfusion injury by sustaining PERK/eIF2α activation and impairing ferredoxin reductase-dependent mitochondrial function	13
Information for Readers	13
Promising novel biomarkers and therapy targets: The application of cell-free seminal nucleotides in male reproduction research	13
Masthead	13
Epididymal white adipose tissue promotes angiotensin II-induced cardiac fibrosis in an exosome-dependent manner	12
Masthead	12
Information for Readers	12
Intermittent caloric restriction protects against diabetic heart inflammation via GSDMD-dependent sFRP2-ATF6-NF-κB pathway	12
Ntsr1 contributes to pulmonary hypertension by enhancing endoplasmic reticulum stress via JAK2-STAT3-Thbs1 signaling	12
Contents	12
Masthead	12
Efficacy of oral manganese and D-galactose therapy in a patient bearing a novel TMEM165 variant	12
Enhancing axonal myelination: Clemastine attenuates cognitive impairment in a rat model of diffuse traumatic brain injury	12
Interplay between pulmonary epithelial stem cells and innate immune cells contribute to the repair and regeneration of ALI/ARDS	12
Masthead	12
Topical captopril: a promising treatment for secondary lymphedema	12
Retinol binding protein 4 promotes the phenotypic transformation of vascular smooth muscle cells under high glucose condition via modulating RhoA/ROCK1 pathway	12
A transcribed ultraconserved noncoding RNA, uc.285+, promotes colorectal cancer proliferation through dual targeting of CDC42 by directly binding mRNA and protein	12
Single-cell RNA sequencing in the context of neuropathic pain: progress, challenges, and prospects	12
Contents	11
Masthead	11
IgG from anti-MDA5⁺ CADM patients impairs NK cell function via CD16 in RP-ILD	11
Masthead	11
Editorial Advisory Board	11
Contents	11
SERPINA1 is a hub gene associated with intervertebral disc degeneration grade and affects the nucleus pulposus cell phenotype through the ADIRF-AS1/miR-214-3p axis	11
Masthead	11
Editorial Advisory Board	11
Contents	11
The key role of cellular plasticity in the development of colorectal cancer	10
NLRP3-mediated inflammation in cardio-oncology: sterile yet harmful	10
Contents	10
Extra-nuclear TERT counteracts oxidative stress and promotes progression in papillary thyroid carcinoma	10

Gender-sex differences in autoimmune atrophic gastritis	10
Progesterone receptor impairs immune respond and down-regulates sensitivity to anti-LAG3 in breast cancer	10
Masthead	10
Unraveling PANoptosis a key player in acute kidney injury and its clinical implications	10
Elevated expression of complement factor I in lung cancer cells associates with shorter survival–Potentially via non-canonical mechanism	10
A key role for NLRP3 signaling in preterm labor and birth driven by the alarmin S100B	10
The proteasome activator REGγ promotes diabetic endothelial impairment by inhibiting HMGA2-GLUT1 pathway	10