Translational Research

Papers
(The TQCC of Translational Research is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Information for Readers412
Clonal hematopoiesis and bone marrow inflammation114
Information for Readers113
Editorial Advisory Board110
Author Guidelines96
Contents87
Contents82
Editorial Advisory Board81
Targeting mutant dicer tumorigenesis in pleuropulmonary blastoma via inhibition of RNA polymerase I74
Information for Readers73
Contents73
Polymerized human hemoglobin with low and high oxygen affinity in trauma models68
An optimal promoter regulating cytokine transgene expression is crucial for safe and effective oncolytic virus immunotherapy66
Multi-Omics Analysis Links Mitochondrial-Related Genes to Idiopathic Pulmonary Fibrosis and In Vivo Transcriptome Validation65
Author Guidelines62
Contents48
Role of tumor endothelial marker 1 (Endosialin/CD248) lectin-like domain in lipopolysaccharide-induced macrophage activation and sepsis in mice48
Interplay between mineral bone disorder and cardiac damage in acute kidney injury: from Ca2+ mishandling and preventive role of Klotho in mice to its potential mortality prediction in human48
Kv1.3 expression on CD4 (+) T cells promotes interleukin-17A-associated airway inflammation and airway remodeling in asthma47
A modified porous silicon microparticle potentiates protective systemic and mucosal immunity for SARS-CoV-2 subunit vaccine47
Potentially functional variants of HBEGF and ITPR3 in GnRH signaling pathway genes predict survival of non-small cell lung cancer patients47
The biomimetic extracellular matrix: a therapeutic tool for breast cancer research45
Hemoglobin induces oxidative stress and mitochondrial dysfunction in oligodendrocyte progenitor cells44
Beta cell functionality and hepatic insulin resistance are major contributors to type 2 diabetes remission and starting pharmacological therapy: from CORDIOPREV randomized controlled trial44
Diabetic wound healing in soft and hard oral tissues43
Single-cell RNA sequencing reveals the MIF/ACKR3 receptor-ligand interaction between neutrophils and nucleus pulposus cells in intervertebral disc degeneration42
Deep next-generation proteomics and network analysis reveal systemic and tissue-specific patterns in Fabry disease40
ASH2L-mediated H3K4me3 drives diabetic nephropathy through HIPK2 and Notch1 pathway39
Understanding the adipose tissue acetylome in obesity and insulin resistance39
Author Guidelines38
COVID-19 Survival and its impact on chronic kidney disease38
Reversal of cisplatin resistance in oral squamous cell carcinoma by piperlongumine loaded smart nanoparticles through inhibition of Hippo-YAP signaling pathway38
Inflammatory arthritis in patients with COVID-1938
Ingenuity and resiliency of syringe service programs on the front lines of the opioid overdose and COVID-19 crises37
Heterogeneous nuclear ribonucleoprotein F deficiency in mouse podocyte promotes podocytopathy mediated by methyltransferase-like 14 nuclear translocation resulting in Sirtuin 1 gene inhibition35
Human lung organoids as a model for respiratory virus replication and countermeasure performance in human hosts35
Contents34
Cardiac-specific overexpression of CREM-IbΔC-X via CRISPR/Cas9 in mice presents a new model of atrial cardiomyopathy with spontaneous atrial fibrillation34
Canagliflozin inhibits hedgehog interacting protein (Hhip) induction of tubulopathy in diabetic Akita mice32
Masthead32
GPX4 transcriptionally promotes liver cancer metastasis via GRHL3/PTEN/PI3K/AKT axis30
Optimization of pig models for translation of subcutaneous pharmacokinetics of therapeutic proteins: Liraglutide, insulin aspart and insulin detemir30
Unlocking the future of cancer diagnosis – promises and challenges of ctDNA-based liquid biopsies in non-small cell lung cancer29
Kidney organoids: a pioneering model for kidney diseases29
Post-COVID-19 patients show an increased endothelial progenitor cell production28
Information for Readers27
Reassessment of mitochondrial cyclophilin D as a target for improving cardiac arrest outcomes in the era of therapeutic hypothermia26
Immune mechanisms in cancer patients that lead to poor outcomes of SARS-CoV-2 infection25
Masthead25
Inhibition of gasdermin D palmitoylation by disulfiram is crucial for the treatment of myocardial infarction25
Editorial Advisory Board24
Masthead24
Editorial Advisory Board24
Contents24
Inhibition of PI3K/C/EBPβ axis in tolerogenic bone marrow-derived dendritic cells of NOD mice promotes Th17 differentiation and diabetes development24
Information for Readers24
Contents23
Editorial Advisory Board23
Impaired glucose regulation, SARS-CoV-2 infections and adverse COVID-19 outcomes23
Information for Readers23
Predictive mouse model reflects distinct stages of human atheroma in a single carotid artery22
Contents22
Brain-derived neurotrophic factor in patients with acute coronary syndrome22
Contents22
Interferon pathway lupus risk alleles modulate risk of death from acute COVID-1922
Information for Readers21
Masthead21
Editorial Advisory Board20
Catalytic iron mediated renal stress responses during experimental cardiorenal syndrome 1 (“CRS-1”)20
Information for Readers20
Overexpressing glyoxalase 1 attenuates acute hyperglycemia–exacerbated neurological deficits of ischemic stroke in mice20
Masthead20
Early growth response protein 2 promotes partial epithelial-mesenchymal transition by phosphorylating Smad3 during renal fibrosis20
Computational drug repositioning of clopidogrel as a novel therapeutic option for focal segmental glomerulosclerosis19
Multi-dimensional metabolomic profiling reveals dysregulated ornithine metabolism hallmarks associated with a severe acute pancreatitis phenotype19
Author Guidelines19
Claudin-1 mediates progression by regulating EMT through AMPK/TGF-β signaling in head and neck squamous cell carcinoma19
Cardiopulmonary bypass with deep hypothermic circulatory arrest results in organ-specific transcriptomic responses in pediatric swine19
Calcium-sensing receptor activator cinacalcet for treatment of cyclic nucleotide-mediated secretory diarrheas19
Repurposing gestrinone for tumor suppressor through P21 reduction regulated by JNK in gynecological cancer19
Masthead18
Author Guidelines18
Author Guidelines18
Contents18
Depleted hexokinase1 and lack of AMPKα activation favor OXPHOS-dependent energetics in retinoblastoma tumors18
Contents18
Contents17
Discovery of CC-99677, a selective targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune disorders17
Toll-like receptor 2 signaling deficiency in cardiac cells ameliorates Ang II-induced cardiac inflammation and remodeling17
From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?17
Masthead17
Influence of immunomodulatory drugs on the gut microbiota17
In Vivo Cardiac-specific Expression of Adenylyl Cyclase 4 Gene Protects against Klotho Deficiency-induced Heart Failure17
Rabies virus glycoprotein 29 (RVG29) promotes CAR-T immunotherapy for glioma17
Corrected cerebral blood flow and reduced cerebral inflammation in berk sickle mice with higher fetal hemoglobin17
Repurposing calcium-sensing receptor activator drug cinacalcet for ADPKD treatment17
Spatial proteomics and transcriptomics of the maternal-fetal interface in placenta accreta spectrum17
Author Guidelines16
RAS protein activator-like 2 (RASAL2) initiates peritubular capillary rarefaction in hypoxic renal interstitial fibrosis16
Contents16
COVID-19 in patients with systemic lupus erythematosus: lessons learned from the inflammatory disease16
Editorial Advisory Board16
Contents16
Information for Readers16
At the intersection of sleep deficiency and opioid use: mechanisms and therapeutic opportunities16
Contents16
Contents16
Contents15
Regulation of nutrient and electrolyte absorption in human organoid-derived intestinal epithelial cell monolayers15
A dual action small molecule enhances azoles and overcomes resistance through co-targeting Pdr5 and Vma115
Breastfeeding by chikungunya virus-infected dams confers resistance to challenge in the offspring15
Emerging evidence on the role of clonal hematopoiesis of indeterminate potential in chronic kidney disease15
Contents15
Chronodisruption and diet associated with increased cardiometabolic risk in coronary heart disease patients: the CORDIOPREV study15
Early vascular aging in chronic kidney disease: focus on microvascular maintenance, senescence signature and potential therapeutics15
A human vascularized microtumor model of patient-derived colorectal cancer recapitulates clinical disease14
The furosemide stress test and computational modeling identify renal damage sites associated with predisposition to acute kidney injury in rats14
Intranasal application of adeno-associated viruses: a systematic review14
Sirtuin-3 mediates sex differences in kidney ischemia-reperfusion injury14
Risk factors for clonal hematopoiesis of indeterminate potential and mosaic chromosomal alterations14
Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use – an exploratory study13
Information for Readers13
SERPINA5 may promote the development of preeclampsia by disruption of the uPA/uPAR pathway13
Contents13
Contents13
Novel MSH2 and TSC2 variants in a Chinese family with Lynch syndrome and their synergistic impact in urothelial carcinoma13
Importance of multiple endocrine cell types in islet organoids for type 1 diabetes treatment13
Contents13
Editorial Advisory Board13
Contents13
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression12
A CD36 transmembrane domain peptide interrupts CD36 interactions with membrane partners on macrophages and inhibits atherogenic functions12
Ntsr1 contributes to pulmonary hypertension by enhancing endoplasmic reticulum stress via JAK2-STAT3-Thbs1 signaling12
DUSP5 deficiency suppresses the progression of acute kidney injury by enhancing autophagy through AMPK/ULK1 pathway12
Contents12
Crosstalk between GABAA receptors in astrocytes and neurons triggered by general anesthetic drugs12
Masthead12
Promising novel biomarkers and therapy targets: The application of cell-free seminal nucleotides in male reproduction research12
Genome-wide characterization of extrachromosomal circular DNA in SLE and functional analysis reveal their association with apoptosis12
Sex-related differences in SIRT3-mediated mitochondrial dynamics in renal ischemia/reperfusion injury12
Information for Readers12
Altered KCa3.1 expression following burn injury and the therapeutic potential of TRAM-34 in post-burn hypertrophic scar formation12
Contents11
A transcribed ultraconserved noncoding RNA, uc.285+, promotes colorectal cancer proliferation through dual targeting of CDC42 by directly binding mRNA and protein11
Interplay between pulmonary epithelial stem cells and innate immune cells contribute to the repair and regeneration of ALI/ARDS11
Masthead11
Efficacy of oral manganese and D-galactose therapy in a patient bearing a novel TMEM165 variant11
Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration11
Editorial Advisory Board11
Contents11
Information for Readers11
Contents11
Topical captopril: a promising treatment for secondary lymphedema11
Enhancing axonal myelination: Clemastine attenuates cognitive impairment in a rat model of diffuse traumatic brain injury11
Retinol binding protein 4 promotes the phenotypic transformation of vascular smooth muscle cells under high glucose condition via modulating RhoA/ROCK1 pathway11
Masthead11
Masthead11
Author Guidelines11
Epididymal white adipose tissue promotes angiotensin II-induced cardiac fibrosis in an exosome-dependent manner11
Single-cell RNA sequencing in the context of neuropathic pain: progress, challenges, and prospects11
Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: Pathologic, physiologic, and detailed molecular profiling11
Extra-nuclear TERT counteracts oxidative stress and promotes progression in papillary thyroid carcinoma10
Masthead10
Elevated expression of complement factor I in lung cancer cells associates with shorter survival–Potentially via non-canonical mechanism10
Endoglin deficiency impairs VEGFR2 but not FGFR1 or TIE2 activation and alters VEGF-mediated cellular responses in human primary endothelial cells10
A key role for NLRP3 signaling in preterm labor and birth driven by the alarmin S100B10
Gene therapy for bone healing: lessons learned and new approaches10
Progesterone receptor impairs immune respond and down-regulates sensitivity to anti-LAG3 in breast cancer10
SERPINA1 is a hub gene associated with intervertebral disc degeneration grade and affects the nucleus pulposus cell phenotype through the ADIRF-AS1/miR-214-3p axis10
Gender-sex differences in autoimmune atrophic gastritis10
NLRP3-mediated inflammation in cardio-oncology: sterile yet harmful10
Masthead10
Molecular mapping of platelet hyperreactivity in diabetes: the stress proteins complex HSPA8/Hsp90/CSK2α and platelet aggregation in diabetic and normal platelets10
Editorial Advisory Board10
Contents10
Editorial Advisory Board10
Masthead10
Development of mRNA manufacturing for vaccines and therapeutics: mRNA platform requirements and development of a scalable production process to support early phase clinical trials10
0.18533992767334