Cell Host & Microbe

Article	Citations
Sowing the seeds of infection	492
Combatting superbugs using the evolutionary record of microbial warfare	461
Microbial genome mining expedition unearths trove of antiviral defenses	288
Breathe and bloom: Gut hypoxia limits C. albicans growth	268
Selenium nanoboosting of plant-beneficial microbiome	267
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes	242
Candidalysin: An unlikely aide for fungal gut commensalism	237
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury	221
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	195
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	193
Epithelial hypoxia maintains colonization resistance against Candida albicans	191
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	182
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation	176
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	173
Secretory IgA: Linking microbes, maternal health, and infant health through human milk	168
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	166
MFSD6 is an entry receptor for respiratory enterovirus D68	162
Engineered bacteria recycle tumor metabolic waste to boost immunotherapy	161
Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria	159
Cad1 turns ATP into phage poison	152
Help from commensals: β-hex to regulate gut immunity	151
Two-for-one: Dual host-microbe functions of S. epidermidis Sph	149
Immunity to fungi and vaccine considerations	145
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome	144
From top to bottom: Staphylococci in atopic dermatitis	142

A broadly distributed predicted helicase/nuclease confers phage resistance via abortive infection	139
There and back again: Discovering antiviral and antiphage defenses using deep homology	137
Beta-carbolines suppress vaginal inflammation	136
Tactical terminase: How a Salmonella prophage navigates oxidative stress	136
Antibiotic treatment ignites a fire that lasts	128
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant	126
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	124
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry	123
Select symbionts drive high IgA levels in the mouse intestine	122
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis	122
Overcoming drug resistance, the natural way	121
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics	121
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	121
Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes	121
A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut	120
Location matters in RSV protection	119
The gut microbiome: Bridging medications and clinical outcomes post stem cell transplantation	118
“AHR-ming” host defense against cryptosporidiosis	118
A lung pathobiont story: Thinking outside the Koch’s postulate box	113
Gut IgA: Never fear, the super inducers are here	111
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	111
Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism	110
Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir	109
Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster	109
Decline in nitrosative stress drives antibiotic persister regrowth during infection	108
Predator-prey interplay: When chemical conversation turns deadly	106
Antibiotics fire up inflammation to cool vaccine responsiveness	105
Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease	104
A single-cell liver atlas of Plasmodium vivax infection	100
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids	100
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding	100
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA	99
Dietary environmental factors shape the immune defense against Cryptosporidium infection	97
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation	97
Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis	95
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes	95
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis	93
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection	92
Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein	91
Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity	89
One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome	89
Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites	89
Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.2	89
Cryptosporidium rhoptry effector protein ROP1 injected during invasion targets the host cytoskeletal modulator LMO7	88
Goodbye PAM: Phage λ’s Red recombination system cripples PAMs and helps dodge CRISPR attacks	87
Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection	87
When NOD ligands become antidotes	85
A counterintuitive antibody cocktail disrupts coxsackievirus	85
Bacteria exploit viral dormancy to establish CRISPR-Cas immunity	84
Brain development in premature infants: A bug in the programming system?	82

AI in microbiome research: Where have we been, where are we going?	82
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease	82
The gut microbiome molecular complex in human health and disease	82
Multi-arming ourselves against drug-resistant bacteria	81
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox	81
Enteric virome negatively affects seroconversion following oral rotavirus vaccination in a longitudinally sampled cohort of Ghanaian infants	81
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome	80
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota	80
Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer	80
A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases	79
Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins	78
Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2	77
On track to tackle dengue: History and future of NS4B ligands	76
E. coli prophages encode an arsenal of defense systems to protect against temperate phages	76
Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption	75
Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses	75
Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS	73
Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses	73
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease	72
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway	71
The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome	71
Infant gut DNA bacteriophage strain persistence during the first 3 years of life	71
GOSpel for tiny allies	71
Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma	70
Thanks, but no thanks: Cholera pathogen keeps incoming DNA at bay	68
Unclouding Clostridiodes difficile virulence with systems biology	68
Cutibacterium acnes evolution: One pore at a time	67
“Indole-gence” for the mind	67
Host-microbe interaction paradigms in acute and recurrent vulvovaginal candidiasis	66
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions	66
Predictive regulatory and metabolic network models for systems analysis of Clostridioides difficile	66
Commensal microbe regulation of skin cells in disease	66
Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity	65
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine	65
An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer	64
Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis	64
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission	62
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease	62
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation	61
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity	61
Gut microbiome development and childhood undernutrition	61
Microbial Cgr2 will let your Th17 cells ROR(γT)	60
Enteric viruses seize their immunomodulatory niche	60
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13	60
Rethinking healthy eating in light of the gut microbiome	60
Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy	59
Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes	58
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization	57
Global COVID-19 vaccine inequity: The scope, the impact, and the challenges	57
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history	56
Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden	56
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species	55
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring	55
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage	55
Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses	55
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis	54
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut	54
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites	53
Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome	53
The gut-brain axis goes viral	52
Growing up: A NOD2 our microbes	52
Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis	52
Even old foes can learn sweet new tricks	52
Linking E. coli to fibrosis in Crohn’s disease	51
Walking down the phosphorylation path to root immunity	50
MAMPs: A devil tamed becomes an angel	50
Multi-armed antibiotics for Gram-positive bacteria	49
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	49
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes	49
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response	49
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	49
Viral mimicry protects from infection when you’re expecting	49
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	48
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	47
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	47
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	47
Going viral: The role of mobile genetic elements in bacterial immunity	47
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	47
A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants	46
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	46

Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	46
Stoking inflammasome fires in the COVID-19 neighborhood	45
An expanded arsenal of immune systems that protect bacteria from phages	45
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	45
License to LAP	45
A colon cancer “prequel”	45
Recording of DNA-binding events reveals the importance of a repurposed Candida albicans regulatory network for gut commensalism	44
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	44
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	44
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?	44
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis	43
HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization	43
Mimicry games: NPC-like MX2 condensates trap viruses	43
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus	42
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	42
The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping	41
The developing infant gut microbiome: A strain-level view	41
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	41
Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis	41
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans	40
Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics	40
Gut microbial enzymes and metabolic dysfunction-associated steatohepatitis: Function, mechanism, and therapeutic prospects	40
Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides	40
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	40
Bacterial molecular syringe for drug delivery	39
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth	39
Pregnancy-associated morbidity and mortality during pandemics: Looking to the past in order to prepare for the future	39
Bacteria renew an OLD protein to cleave host tRNAs and block phage translation	39
Compensating P. falciparum artemisinin resistance	39
It takes a plant village to raise a microbiome	38
Oh, how we have grown!	38
A new piece of the microbiota pie: Mining ‘omics for DNA inversion states	38
RTS,S today and tomorrow’s science	38
Mg and the microbiome: A liver-protective duo	38
Stitching together a healthy gut microbiome with fiber	38
Molecular basis for inhibition of type III-B CRISPR-Cas by an archaeal viral anti-CRISPR protein	37
Designing boosting immunogens for HIV-1 vaccine development	37
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein	36
Differences in carbon metabolic capacity fuel co-existence and plasmid transfer between Salmonella strains in the mouse gut	36
BCG: From veins to correlates	36
One size might fit all: Indole-3-propionic acid potentiates pan-cancer immunotherapy	36
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont	36
Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans	36
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure	35
Sensing a pattern: Overlapping immunity in bacteria and eukaryotes	35
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity	35
Won’t you be my neighbor? The importance of biogeography and nutrient niches in the gut	35
RNA editing of genomic neighbors controls antiviral response in fungi	34
Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens	34
What E. coli knows about your 1-year-old infant: Antibiotic use, lifestyle, birth mode, and siblings	34
Long live the king: Toxoplasma gondii nucleomodulin inhibits necroptotic cell death	34
Cryptosporidium modifies intestinal microvilli through an exported virulence factor	34
Happy families	34
A unique mode of nucleic acid immunity performed by a multifunctional bacterial enzyme	34