Cell Host & Microbe

Article	Citations
Waste as an antibacterial weapon	421
Microbial genome mining expedition unearths trove of antiviral defenses	396
Sowing the seeds of infection	392
Candidalysin: An unlikely aide for fungal gut commensalism	342
Hide and seek: Cryptococcus evasion of microglial sensing enables meningitis	281
Selenium nanoboosting of plant-beneficial microbiome	249
When predators meet the matrix: Natural resistance via amyloid fibers	244
Combatting superbugs using the evolutionary record of microbial warfare	243
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	222
Engineered probiotics recruit CAR macrophages and establish immune memory to eradicate heterogeneous glioblastoma in mice	204
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation	200
Crosstalk between three CRISPR-Cas types enables primed type VI-A adaptation in Listeria seeligeri	186
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	185
An infant nasal microbial gene atlas uncovers intervention-driven microbiome shifts and salt-resistant pathogen expansion	177
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes	175
Breathe and bloom: Gut hypoxia limits C. albicans growth	175
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	174
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	172
MFSD6 is an entry receptor for respiratory enterovirus D68	161
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	160
Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation	159
A CLOCK-targeting lncRNA induces trained immunity against tuberculosis	158
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury	157
Epithelial hypoxia maintains colonization resistance against Candida albicans	157
Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects	152

There and back again: Discovering antiviral and antiphage defenses using deep homology	146
How hosts accurately command bacteria for gut health	139
Help from commensals: β-hex to regulate gut immunity	139
A bacterial signal coordinates plant-microbe fitness trade-off to enhance sulfur deficiency tolerance in plants	138
Uniting against enteric invaders: IgA meets its microbial ally	138
From top to bottom: Staphylococci in atopic dermatitis	135
Antibiotic treatment ignites a fire that lasts	133
Tactical terminase: How a Salmonella prophage navigates oxidative stress	130
Immunity to fungi and vaccine considerations	128
Evolution of root nodule symbiosis via paleopolyploidy and modular pathway rewiring	127
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	127
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	126
Select symbionts drive high IgA levels in the mouse intestine	125
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics	125
Beta-carbolines suppress vaginal inflammation	122
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome	121
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry	120
Cad1 turns ATP into phage poison	119
Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes	118
A broadly distributed predicted helicase/nuclease confers phage resistance via abortive infection	117
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant	116
Lost and found: Reconstituting PRR immune function through co-receptor transfer	115
Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites	110
“AHR-ming” host defense against cryptosporidiosis	109
Predator-prey interplay: When chemical conversation turns deadly	109
Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster	107
Antibiotics fire up inflammation to cool vaccine responsiveness	106
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	103
A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut	102
One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome	101
The gut microbiome: Bridging medications and clinical outcomes post stem cell transplantation	100
Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein	100
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids	99
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes	99
A lung pathobiont story: Thinking outside the Koch’s postulate box	98
Dietary environmental factors shape the immune defense against Cryptosporidium infection	95
Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.2	95
Decline in nitrosative stress drives antibiotic persister regrowth during infection	95
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis	94
A single-cell liver atlas of Plasmodium vivax infection	93
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation	92
Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity	91
Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease	89
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection	87
Molecular basis of 60 years of antigenic evolution of human influenza A(H3N2) virus neuraminidase	85
Gut IgA: Never fear, the super inducers are here	85
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding	83
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA	83
GOSpel for tiny allies	82
When NOD ligands become antidotes	82

A counterintuitive antibody cocktail disrupts coxsackievirus	82
The gut microbiome molecular complex in human health and disease	81
Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins	81
The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome	81
Multi-arming ourselves against drug-resistant bacteria	80
Systems virology as a cornerstone for pandemic responsiveness: A G2P-Japan perspective	78
Microbes as architects of colonic patterning	77
Methylglyoxal is an antibacterial effector produced by macrophages during infection	77
Long-chain unsaturated fatty acids released during immune responses stimulate host-microbe trans-kingdom communication	75
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway	75
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease	74
Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system	72
A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases	72
Maternal helminths rewire the microbiota to promote offspring antiviral immunity	71
E. coli prophages encode an arsenal of defense systems to protect against temperate phages	70
Bacteria exploit viral dormancy to establish CRISPR-Cas immunity	70
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome	70
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease	70
Restoring a gut Bifidobacterium community in early infancy	70
AI in microbiome research: Where have we been, where are we going?	69
Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS	69
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox	69
Infant gut DNA bacteriophage strain persistence during the first 3 years of life	69
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota	68
Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma	67
Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption	66
“Indole-gence” for the mind	65
All systems go: CRISPR crosstalk for enhanced immunity	65
Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses	65
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13	65
An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer	64
The Africa COVID-19 legacy—Improved vaccinology for pandemic preparedness	64
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation	64
Thanks, but no thanks: Cholera pathogen keeps incoming DNA at bay	63
A global survey of taxa-metabolic associations across mouse microbiome communities	63
Commensal microbe regulation of skin cells in disease	63
Metabolic cross-feeding of a dietary antioxidant enhances anaerobic energy metabolism by human gut bacteria	62
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity	62
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease	61
Rethinking healthy eating in light of the gut microbiome	61
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions	60
Host-microbe interaction paradigms in acute and recurrent vulvovaginal candidiasis	60
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine	60
Gut bacteria help the brain with an oil change	59
Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy	59
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history	58
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage	58
Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses	58
Protist predators engineer bacterial metabolic cooperation	58
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species	58
Environmental and maternal imprints on infant gut metabolic development	58
Outsmarting the wicked smart: Using chemistry to overcome bacterial anti-viral systems	58
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring	57
Epigenetic phase variation in the gut microbiome enhances bacterial adaptation	57
Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes	57
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis	57
Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis	56
Bacterial entrapment of a fungal carbon repressor prevents plant colonization	56
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization	56
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites	55
Growing up: A NOD2 our microbes	55
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut	55
Linking E. coli to fibrosis in Crohn’s disease	53
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	53
Multi-armed antibiotics for Gram-positive bacteria	53
Deep learning helps fight against antibiotic resistance	52
MAMPs: A devil tamed becomes an angel	51
A. baumannii’s nutrient tug-of-war	51
Walking down the phosphorylation path to root immunity	51
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	50
Vaginal microbiota impacts of a Lactobacillus crispatus live biotherapeutic and predictors of colonization in randomized controlled trial	50
Microbiota utilization of intestinal amino acids modulates cancer progression and anticancer immunity	50
Viral mimicry protects from infection when you’re expecting	50
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	50
Making room for gut prophages in human health	49
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes	47
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	47
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	47
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	47
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	46

Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	46
Going viral: The role of mobile genetic elements in bacterial immunity	46
Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts	45
An expanded arsenal of immune systems that protect bacteria from phages	45
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	45
Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	45
Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma	45
Stoking inflammasome fires in the COVID-19 neighborhood	44
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans	44
Crisping up Lactobacillus vaginal live biotherapeutics	44
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?	44
The impact of COVID-19 on children and lessons for pandemic preparedness	43
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	43
Bacteria block host cell death by protein cut-and-paste	43
Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin	42
Mimicry games: NPC-like MX2 condensates trap viruses	42
Gut microbiota-derived indole-3-lactic acid suppresses anti-PD-1 efficacy in esophageal squamous cell carcinoma	42
The DanRI regulatory system in uropathogenic Escherichia coli subverts neutrophil responses	41
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	41
Fungal resistance in rice is restored by interfamily transfer of an evolutionarily lost co-receptor	40
The skin microbiota drives cutaneous immune checkpoint inhibitor toxicity in genetically susceptible mice	40
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus	40
The microbial metabolite imidazole propionate modulates hypothalamic activity and stress-induced behaviors	40
Common mycorrhizal networks facilitate plant disease resistance by altering rhizosphere microbiome assembly	40
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	40
Gut microbial enzymes and metabolic dysfunction-associated steatohepatitis: Function, mechanism, and therapeutic prospects	40
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	40
Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis	40
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	40
A new piece of the microbiota pie: Mining ‘omics for DNA inversion states	40
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis	40
The HY5-NPR1 module governs light-dependent virulence of a plant bacterial pathogen	39
Stitching together a healthy gut microbiome with fiber	39
It takes a plant village to raise a microbiome	39
Bacteria renew an OLD protein to cleave host tRNAs and block phage translation	39
BCG: From veins to correlates	39
The female urogenital microbiome: Ecological insights, therapeutic strategies, and molecular mechanisms	38
Differences in carbon metabolic capacity fuel co-existence and plasmid transfer between Salmonella strains in the mouse gut	38
Molecular basis for inhibition of type III-B CRISPR-Cas by an archaeal viral anti-CRISPR protein	38
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity	38
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein	37
Pregnancy-associated morbidity and mortality during pandemics: Looking to the past in order to prepare for the future	37
Bacterial molecular syringe for drug delivery	37
One size might fit all: Indole-3-propionic acid potentiates pan-cancer immunotherapy	37
Designing boosting immunogens for HIV-1 vaccine development	36
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth	36
Microbial communities in semi-mature oak trees are resilient to drought, nutrient limitation, and pathogen challenge	36
Metagenomic selections reveal diverse antiphage defenses in human and environmental microbiomes	36
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure	36
‘Insane in the membrane’: 2′,3′-cGAMP triggers filamentous phage defense	36
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont	35
Host hepatic metabolism is modulated by gut microbiota-derived sphingolipids	35
Bioengineered gut bacterium synthesizing levodopa alleviates motor deficits in models of Parkinson’s disease	35
Gut microbiota and metabolites drive chronic sickle cell disease pain in mice	35
Mg and the microbiome: A liver-protective duo	35
Charting a phage genome atlas	34
Sensing a pattern: Overlapping immunity in bacteria and eukaryotes	34
Inter-kingdom lipid messengers sustain gut harmony	34
Mechanisms of bacterial immunity, protection, and survival during interbacterial warfare	34
Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens	34
Rothia mucilaginosa membrane vesicles stabilize labile iron to alleviate UVB-induced ferroptosis	33
Fishing for obesity-related gut microbiome enterotype	33