Cell Host & Microbe

Article	Citations
Viral mimicry protects from infection when you’re expecting	486
Breathe and bloom: Gut hypoxia limits C. albicans growth	479
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	475
Secretory IgA: Linking microbes, maternal health, and infant health through human milk	410
The dominoes fall after long-term antibiotic exposure	316
Accelerating mammalian filovirus research with receptor binding blueprints	294
MFSD6 is an entry receptor for respiratory enterovirus D68	292
Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection	279
Sowing the seeds of infection	253
Virus hunters: Discovering the evolutionary origins of SARS-CoV-2	249
Direct comparison of antibody responses to four SARS-CoV-2 vaccines in Mongolia	236
Selenium nanoboosting of plant-beneficial microbiome	219
Multi-omics signatures reveal genomic and functional heterogeneity of Cutibacterium acnes in normal and diseased skin	211
Enhanced neutralization resistance of SARS-CoV-2 Omicron subvariants BQ.1, BQ.1.1, BA.4.6, BF.7, and BA.2.75.2	203
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation	187
Global, distinctive, and personal changes in molecular and microbial profiles by specific fibers in humans	174
Norovirus cell tropism: The road to uncovering its secret hideout	173
Commensals make the most of their hosts	171
Trick and no treat: Carbohydrate preemption by commensal Enterobacteriaceae	170
Neutrophils flash their GLUTs to beat back detestable fungi	169
Even old foes can learn sweet new tricks	162
Salmonella “RecAmends” self-healing	156
Find a little help from my (microbial) friends	153
Holding back: HLA-associated inhibition of NK cells gives HIV a leg up	148
The devil in the details: Herd immunity and pandemic response	143

From parent to progeny	142
A single-nucleotide polymorphism in Helicobacter pylori promotes gastric cancer development	141
From poo to promise: Fecal microbiota transplants support immunotherapy re-sensitization in solid tumors	139
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes	137
The gut-brain axis goes viral	135
The quest for control	133
Divide and conquer: Spatiotemporal plant innate immunity at single-cell resolution	130
Ecological diversity profiles of non-vaccine-targeted HPVs after gender-based community vaccination efforts	129
Salmonella-liberated dietary L-arabinose promotes expansion in superspreaders	128
Linking E. coli to fibrosis in Crohn’s disease	123
Commensal fungi, a force to be reckoned with	122
Engineered bacteria recycle tumor metabolic waste to boost immunotherapy	118
Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller	117
Fighting the invisible foe in cancer therapy	117
Walking down the phosphorylation path to root immunity	116
Mommy’s microbes: Gestational diabetes mellitus shapes the maternal and infant gut microbiome	116
Type I IFN-mediated NET release promotes Mycobacterium tuberculosis replication and is associated with granuloma caseation	116
Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies	116
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	115
Fungi make fun guys	113
Bacteroides acidifaciens drives a liver detox program	112
mRNA vaccines: A promising platform for safer, more effective next-generation Orthopoxvirus immunization	111
INDELible impact: How structural variants drive virulence and resistance	110
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	110
A large-scale type I CBASS antiphage screen identifies the phage prohead protease as a key determinant of immune activation and evasion	109
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes	108
MAMPs: A devil tamed becomes an angel	108
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	106
Going viral: The role of mobile genetic elements in bacterial immunity	106
Stealth strategies of Candida albicans to evade host immunity	103
SARS-CoV-2 Omicron sublineages show comparable cell entry but differential neutralization by therapeutic antibodies	103
Rapid design of bacteriophage cocktails to suppress the burden and virulence of gut-resident carbapenem-resistant Klebsiella pneumoniae	103
Microbiome modification for personalized treatment of dysbiotic diseases	102
Combatting superbugs using the evolutionary record of microbial warfare	102
A prophage competition element protects Salmonella from lysis	101
Candida lipase packs a punch against IL-17	96
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	96
Detect and destroy: CRISPR-based technologies for the response against viruses	95
Candidalysin: An unlikely aide for fungal gut commensalism	94
Assessing phage-host population dynamics by reintroducing virulent viruses to synthetic microbiomes	94
Microbial genome mining expedition unearths trove of antiviral defenses	90
Identification of host regulators of Mycobacterium tuberculosis phenotypes uncovers a role for the MMGT1-GPR156 lipid droplet axis in persistence	89
Fecal matters: Microbial signatures distinguish clinically relevant subtypes of precancerous colorectal polyps	89
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	87
Growing up: A NOD2 our microbes	87
Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode	87
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	86
Rethinking phage-bacteria-eukaryotic relationships and their influence on human health	86
Human cytomegalovirus degrades DMXL1 to inhibit autophagy, lysosomal acidification, and viral assembly	86
Stress-induced condensate switch awakens sleeping viruses	85

Innate immune sensing of rotavirus by intestinal epithelial cells leads to diarrhea	84
It takes three: A cocktail of protists, bacterial sphingolipids and an inflammasome	84
Boosting endosymbiosis in plants for future self-sustained crop production	84
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	83
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	83
The blue-light receptor CRY1 serves as a switch to balance photosynthesis and plant defense	82
Gut commensals expand vitamin A metabolic capacity of the mammalian host	81
Long-term evolution and short-term adaptation of microbiota strains and sub-strains in mice	80
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response	80
Evolutionarily conserved bacterial effectors hijack abscisic acid signaling to induce an aqueous environment in the apoplast	79
Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria	78
Mechanism of phage sensing and restriction by toxin-antitoxin-chaperone systems	78
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19	78
Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics	75
Signatures of antagonistic pleiotropy in a bacterial flagellin epitope	74
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	73
Worming into infancy: Exploring helminth-microbiome interactions in early life	73
Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	73
Argonaute-CLIP delineates versatile, functional RNAi networks in Aedes aegypti, a major vector of human viruses	72
Persistent Salmonella infections in humans are associated with mutations in the BarA/SirA regulatory pathway	72
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	72
Epithelial hypoxia maintains colonization resistance against Candida albicans	72
Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease	71
Salmonella Typhimurium expansion in the inflamed murine gut is dependent on aspartate derived from ROS-mediated microbiota lysis	71
A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants	71
Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome	71
A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1	70
RNAi, a sword of plant seeds to combat viral infections	70
Trained immunity: Target for prophylaxis and therapy	70
Precision microbial intervention improves social behavior but not autism severity: A pilot double-blind randomized placebo-controlled trial	69
Fiber-deficient diets reprogram the microbiota	68
Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1	67
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	66
A short prokaryotic Argonaute activates membrane effector to confer antiviral defense	66
Prophages encode phage-defense systems with cognate self-immunity	66
Phages and their satellites encode hotspots of antiviral systems	66
Opposing diet, microbiome, and metabolite mechanisms regulate inflammatory bowel disease in a genetically susceptible host	65
An expanded arsenal of immune systems that protect bacteria from phages	65
High-fat diet disrupts REG3γ and gut microbial rhythms promoting metabolic dysfunction	64
A Gpr35-tuned gut microbe-brain metabolic axis regulates depressive-like behavior	63
Early life host-microbe interactions in skin	63
Longitudinal comparison of the developing gut virome in infants and their mothers	63
Multi-armed antibiotics for Gram-positive bacteria	63
A complex immune response to flagellin epitope variation in commensal communities	61
Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria	61
Interaction between Staphylococcus Agr virulence and neutrophils regulates pathogen expansion in the skin	61
Commensal microbiota regulates skin barrier function and repair via signaling through the aryl hydrocarbon receptor	61
Characterization of gut microbial structural variations as determinants of human bile acid metabolism	60
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	60
Enteric VIP-producing neurons maintain gut microbiota homeostasis through regulating epithelium fucosylation	60
Colonization of the live biotherapeutic product VE303 and modulation of the microbiota and metabolites in healthy volunteers	59
Mycobacterium tuberculosis suppresses host DNA repair to boost its intracellular survival	59
A necrotizing toxin enables Pseudomonas syringae infection across evolutionarily divergent plants	59
A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans	59
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	58
Anatomy promotes neutral coexistence of strains in the human skin microbiome	58
Gut commensal E. coli outer membrane proteins activate the host food digestive system through neural-immune communication	58
Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization	58
Developmental trajectory of the healthy human gut microbiota during the first 5 years of life	57
Establishment and characterization of stable, diverse, fecal-derived in vitro microbial communities that model the intestinal microbiota	57
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	57
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	56
An atlas of continuous adaptive evolution in endemic human viruses	56
Guilds as guides for health vs. disease	55
Duffy antigen is expressed during erythropoiesis in Duffy-negative individuals	54
A selfish bacteriocin dictates pneumococcal domination	52
tHIS way to cognitive development	52
Plant growth promotion through repression of defenses by leaf microbiota	52
Antibiotic treatment ignites a fire that lasts	51
The evolutionary potential of influenza A virus hemagglutinin is highly constrained by epistatic interactions with neuraminidase	51
Symbionts of predatory protists are widespread in the oceans and related to animal pathogens	51
Skin-deep immune sensing	50
A colon cancer “prequel”	50
Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning	50
Antibacterial action, proteolytic immunity, and in vivo activity of a Vibrio cholerae microcin	48
Road to the discovery of HO-2’s myristate binding activity	48
Antiviral RNA interference inhibits virus vertical transmission in plants	48
Beta-carbolines suppress vaginal inflammation	47
Two-for-one: Dual host-microbe functions of S. epidermidis Sph	47
Robbing the thief	47

Hair of the mouse: A skin bacteria “cocktail” gets follicles back on their feet	46
SnapShot: The Expobiome Map	45
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	45
Cad1 turns ATP into phage poison	45
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	44
Helminths are positively AMPing up gut de-bugging	44
Help from commensals: β-hex to regulate gut immunity	44
Diet leaves a genetic signature in a keystone member of the gut microbiota	44
Bugs take the sting out	43
Candida albicans accelerates atherosclerosis by activating intestinal hypoxia-inducible factor2α signaling	43
Protection against Clostridioides difficile disease by a naturally avirulent strain	43
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	42
The butterfly effect of the strain richness influences the efficacy of microbiota transplantation	42
A layered effect in bacterial defense	42
Gut microbiome and bladder cancer: A new link through nitrosamine metabolism	41
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	40
Human influenza virus challenge identifies cellular correlates of protection for oral vaccination	40
From top to bottom: Staphylococci in atopic dermatitis	40
Lessons learned by an organic chemist entering the microbiome field	40
Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning	40
Fatty liver? Microbiome sphingolipids to the rescue	40
Regulators of male and female sexual development are critical for the transmission of a malaria parasite	40
There and back again: Discovering antiviral and antiphage defenses using deep homology	39
Fungal influence: The role of the gut mycobiome in women’s health	39
Immunity to fungi and vaccine considerations	39
Clinical sequelae of gut microbiome development and disruption in hospitalized preterm infants	39
Intestinal newborn regulatory B cell antibodies modulate microbiota communities	38
The bad neighbor: Prophage competition in Salmonella during macrophage infection	38
A metagenome-assembled genome inventory for children reveals early-life gut bacteriome and virome dynamics	38
Streptomyces use umbrella toxins to gently compete with kin	38
Beyond neutralization for BNT162b2 mRNA vaccination	38
A trivalent mucosal vaccine encoding phylogenetically inferred ancestral RBD sequences confers pan-Sarbecovirus protection in mice	38
Quorum sensing-activated phenylalanine metabolism drives OMV biogenesis to enhance mosquito commensal colonization resistance to Plasmodium	37
The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr	37
The complete Kaposi sarcoma-associated herpesvirus genome induces early-onset, metastatic angiosarcoma in transgenic mice	37
Emergence and widespread circulation of a recombinant SARS-CoV-2 lineage in North America	36
Partial protection against P. vivax infection diminishes hypnozoite burden and blood-stage relapses	36
Diarrheal pathogens trigger rapid evolution of the guanylate cyclase-C signaling axis in bats	36
Fusobacterium nucleatum subsp. animalis comes to the spotlight in oral diseases	36
An aberrant inflammatory response in severe COVID-19	36
Non-protective immune imprint underlies failure of Staphylococcus aureus IsdB vaccine	36
Stoking inflammasome fires in the COVID-19 neighborhood	35
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis	35
HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization	35
Can maternal-child microbial seeding interventions improve the health of infants delivered by Cesarean section?	35
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome	35
To err is human, to forgive may require different vaccines	35
Tactical terminase: How a Salmonella prophage navigates oxidative stress	35
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	33
Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes	33
A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection	33
License to LAP	33
Milk to mucus: How B. fragilis colonizes the gut	33
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	33
Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway	33
Defined mouse microbiota: An “evolving” tool	33