Cell Host & Microbe

Article	Citations
Waste as an antibacterial weapon	487
Sowing the seeds of infection	427
Candidalysin: An unlikely aide for fungal gut commensalism	422
Hide and seek: Cryptococcus evasion of microglial sensing enables meningitis	376
Selenium nanoboosting of plant-beneficial microbiome	302
Combatting superbugs using the evolutionary record of microbial warfare	277
Breathe and bloom: Gut hypoxia limits C. albicans growth	262
When predators meet the matrix: Natural resistance via amyloid fibers	246
Crosstalk between three CRISPR-Cas types enables primed type VI-A adaptation in Listeria seeligeri	225
An infant nasal microbial gene atlas uncovers intervention-driven microbiome shifts and salt-resistant pathogen expansion	214
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury	203
MFSD6 is an entry receptor for respiratory enterovirus D68	202
A CLOCK-targeting lncRNA induces trained immunity against tuberculosis	200
Microbial genome mining expedition unearths trove of antiviral defenses	197
Mining the code of life for new antibiotics	186
Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation	183
Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects	182
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	182
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	172
Engineered probiotics recruit CAR macrophages and establish immune memory to eradicate heterogeneous glioblastoma in mice	171
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	166
Epithelial hypoxia maintains colonization resistance against Candida albicans	164
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	159
There and back again: Discovering antiviral and antiphage defenses using deep homology	159
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	159

Help from commensals: β-hex to regulate gut immunity	158
How hosts accurately command bacteria for gut health	156
Uniting against enteric invaders: IgA meets its microbial ally	154
Tactical terminase: How a Salmonella prophage navigates oxidative stress	152
Cad1 turns ATP into phage poison	151
From top to bottom: Staphylococci in atopic dermatitis	146
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome	141
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	139
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant	131
A broadly distributed predicted helicase/nuclease confers phage resistance via abortive infection	130
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics	128
Immunity to fungi and vaccine considerations	127
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry	127
Beta-carbolines suppress vaginal inflammation	127
A bacterial signal coordinates plant-microbe fitness trade-off to enhance sulfur deficiency tolerance in plants	126
Select symbionts drive high IgA levels in the mouse intestine	126
Toward precision microbiome therapeutics: From black box to blueprint	125
Evolution of root nodule symbiosis via paleopolyploidy and modular pathway rewiring	119
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	118
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA	115
Lost and found: Reconstituting PRR immune function through co-receptor transfer	113
“AHR-ming” host defense against cryptosporidiosis	112
Antibiotics fire up inflammation to cool vaccine responsiveness	111
Predator-prey interplay: When chemical conversation turns deadly	111
The gut microbiome: Bridging medications and clinical outcomes post stem cell transplantation	110
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes	109
A lung pathobiont story: Thinking outside the Koch’s postulate box	108
Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity	104
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis	104
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	100
Gut IgA: Never fear, the super inducers are here	100
Dietary environmental factors shape the immune defense against Cryptosporidium infection	99
Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.2	97
Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster	97
Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease	95
An acidic welcome: How microbial metabolites keep fungi in line	94
Molecular basis of 60 years of antigenic evolution of human influenza A(H3N2) virus neuraminidase	93
Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein	93
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection	91
One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome	90
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids	90
A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut	88
RNA quality control enables antibiotic tolerance	88
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding	88
Decline in nitrosative stress drives antibiotic persister regrowth during infection	87
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation	86
Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites	86
A counterintuitive antibody cocktail disrupts coxsackievirus	85
When NOD ligands become antidotes	85
Multi-arming ourselves against drug-resistant bacteria	83

GOSpel for tiny allies	83
Systems virology as a cornerstone for pandemic responsiveness: A G2P-Japan perspective	82
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome	81
Restoring a gut Bifidobacterium community in early infancy	79
AI in microbiome research: Where have we been, where are we going?	78
Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system	78
Infant gut DNA bacteriophage strain persistence during the first 3 years of life	76
Long-chain unsaturated fatty acids released during immune responses stimulate host-microbe trans-kingdom communication	76
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease	75
Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma	75
The gut microbiome molecular complex in human health and disease	75
Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins	74
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox	74
A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases	74
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway	74
Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses	73
Maternal helminths rewire the microbiota to promote offspring antiviral immunity	72
Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS	72
The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome	72
Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption	72
Microbes as architects of colonic patterning	69
E. coli prophages encode an arsenal of defense systems to protect against temperate phages	68
Methylglyoxal is an antibacterial effector produced by macrophages during infection	68
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota	67
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease	67
Bacteria exploit viral dormancy to establish CRISPR-Cas immunity	67
Host-microbe interaction paradigms in acute and recurrent vulvovaginal candidiasis	66
The Africa COVID-19 legacy—Improved vaccinology for pandemic preparedness	66
All systems go: CRISPR crosstalk for enhanced immunity	66
“Indole-gence” for the mind	66
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine	65
Single-cell detection and quantification of the microbiota by MicFLY	65
The gut microbiota directs vitamin A flux to regulate intestinal T cell development	65
A global survey of taxa-metabolic associations across mouse microbiome communities	64
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation	64
NAD to the bone: How bacteria put phages under aRES-t … and how phages fight back	64
Metabolic cross-feeding of a dietary antioxidant enhances anaerobic energy metabolism by human gut bacteria	64
Operationalizing microbiome ecology in cancer care	64
Commensal microbe regulation of skin cells in disease	63
Engineering oral commensal nanovaccines to activate mucosal-systemic immune cascades against tumor	63
An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer	63
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13	61
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions	61
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history	60
Outsmarting the wicked smart: Using chemistry to overcome bacterial anti-viral systems	60
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity	60
Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy	60
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease	60
Bacterial entrapment of a fungal carbon repressor prevents plant colonization	59
Environmental and maternal imprints on infant gut metabolic development	59
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut	59
Protist predators engineer bacterial metabolic cooperation	59
Gut bacteria help the brain with an oil change	59
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization	58
Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development	57
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage	57
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis	57
Epigenetic phase variation in the gut microbiome enhances bacterial adaptation	57
Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes	57
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species	56
Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses	55
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites	55
Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis	53
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring	52
Growing up: A NOD2 our microbes	51
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	51
Linking E. coli to fibrosis in Crohn’s disease	51
MAMPs: A devil tamed becomes an angel	50
A. baumannii’s nutrient tug-of-war	50
Walking down the phosphorylation path to root immunity	50
Vaginal microbiota impacts of a Lactobacillus crispatus live biotherapeutic and predictors of colonization in randomized controlled trial	49
Viral mimicry protects from infection when you’re expecting	49
Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts	48
Deep learning helps fight against antibiotic resistance	48
Improving the vaccine efficacy gap with microbial-derived therapies	48
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	48
Making room for gut prophages in human health	48
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	48
Going viral: The role of mobile genetic elements in bacterial immunity	48
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	48

Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	47
Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma	46
Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	46
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	46
Multi-armed antibiotics for Gram-positive bacteria	46
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	46
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	45
Microbiota utilization of intestinal amino acids modulates cancer progression and anticancer immunity	44
An expanded arsenal of immune systems that protect bacteria from phages	44
Bacteria block host cell death by protein cut-and-paste	44
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	44
The impact of COVID-19 on children and lessons for pandemic preparedness	44
Gut microbiota-derived indole-3-lactic acid suppresses anti-PD-1 efficacy in esophageal squamous cell carcinoma	43
The skin microbiota drives cutaneous immune checkpoint inhibitor toxicity in genetically susceptible mice	43
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus	43
Stoking inflammasome fires in the COVID-19 neighborhood	43
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	42
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans	42
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	42
Fungal resistance in rice is restored by interfamily transfer of an evolutionarily lost co-receptor	42
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?	41
Gut microbial enzymes and metabolic dysfunction-associated steatohepatitis: Function, mechanism, and therapeutic prospects	41
Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis	41
Mimicry games: NPC-like MX2 condensates trap viruses	41
Co-opting cross-kingdom contact to boost bacterial pathogenicity	41
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	41
Crisping up Lactobacillus vaginal live biotherapeutics	41
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	41
Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin	40
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis	40
Suppression of host salicylic acid defense by a phloem-colonizing pathogen effector in citrus Huanglongbing	40
Common mycorrhizal networks facilitate plant disease resistance by altering rhizosphere microbiome assembly	39
BCG: From veins to correlates	39
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein	39
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	39
The microbial metabolite imidazole propionate modulates hypothalamic activity and stress-induced behaviors	39
Bacteria renew an OLD protein to cleave host tRNAs and block phage translation	39
The DanRI regulatory system in uropathogenic Escherichia coli subverts neutrophil responses	39
A new piece of the microbiota pie: Mining ‘omics for DNA inversion states	39
It takes a plant village to raise a microbiome	39
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity	38
The HY5-NPR1 module governs light-dependent virulence of a plant bacterial pathogen	38
Molecular basis for inhibition of type III-B CRISPR-Cas by an archaeal viral anti-CRISPR protein	37
Pregnancy-associated morbidity and mortality during pandemics: Looking to the past in order to prepare for the future	37
Microbial communities in semi-mature oak trees are resilient to drought, nutrient limitation, and pathogen challenge	37
‘Insane in the membrane’: 2′,3′-cGAMP triggers filamentous phage defense	37
Bacterial molecular syringe for drug delivery	36
Mg and the microbiome: A liver-protective duo	36
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont	36
Designing boosting immunogens for HIV-1 vaccine development	36
Variations in the latitudinal diversity gradients of the ocean microbiome	35
Bioengineered gut bacterium synthesizing levodopa alleviates motor deficits in models of Parkinson’s disease	35
One size might fit all: Indole-3-propionic acid potentiates pan-cancer immunotherapy	35
YprA-family helicases provide the missing link between diverse prokaryotic immune systems	34
Metagenomic selections reveal diverse antiphage defenses in human and environmental microbiomes	34
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure	34
Gut microbiota and metabolites drive chronic sickle cell disease pain in mice	34
Gabija restricts phage circularization and DNA replication	34
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth	34
RNA editing of genomic neighbors controls antiviral response in fungi	33
Differences in carbon metabolic capacity fuel co-existence and plasmid transfer between Salmonella strains in the mouse gut	33
Sensing a pattern: Overlapping immunity in bacteria and eukaryotes	33
Inter-kingdom lipid messengers sustain gut harmony	33
The female urogenital microbiome: Ecological insights, therapeutic strategies, and molecular mechanisms	33
Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies	33
Charting a phage genome atlas	33