Cell Host & Microbe

Article	Citations
Sowing the seeds of infection	534
Microbial genome mining expedition unearths trove of antiviral defenses	298
Selenium nanoboosting of plant-beneficial microbiome	263
Candidalysin: An unlikely aide for fungal gut commensalism	252
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	229
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes	222
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation	204
MFSD6 is an entry receptor for respiratory enterovirus D68	202
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury	194
Combatting superbugs using the evolutionary record of microbial warfare	187
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	180
Crosstalk between three CRISPR-Cas types enables primed type VI-A adaptation in Listeria seeligeri	179
Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation	177
Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria	170
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	170
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	168
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	151
Secretory IgA: Linking microbes, maternal health, and infant health through human milk	148
Engineered bacteria recycle tumor metabolic waste to boost immunotherapy	147
Epithelial hypoxia maintains colonization resistance against Candida albicans	145
Breathe and bloom: Gut hypoxia limits C. albicans growth	144
Waste as an antibacterial weapon	142
Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects	141
Cad1 turns ATP into phage poison	139
Help from commensals: β-hex to regulate gut immunity	138

Two-for-one: Dual host-microbe functions of S. epidermidis Sph	135
Immunity to fungi and vaccine considerations	135
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry	133
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant	133
A broadly distributed predicted helicase/nuclease confers phage resistance via abortive infection	132
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics	130
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	128
Beta-carbolines suppress vaginal inflammation	125
There and back again: Discovering antiviral and antiphage defenses using deep homology	125
Tactical terminase: How a Salmonella prophage navigates oxidative stress	124
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis	122
From top to bottom: Staphylococci in atopic dermatitis	118
Select symbionts drive high IgA levels in the mouse intestine	116
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome	111
Antibiotic treatment ignites a fire that lasts	111
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	109
How hosts accurately command bacteria for gut health	106
Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes	105
Overcoming drug resistance, the natural way	102
Uniting against enteric invaders: IgA meets its microbial ally	102
Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity	100
The gut microbiome: Bridging medications and clinical outcomes post stem cell transplantation	99
A lung pathobiont story: Thinking outside the Koch’s postulate box	99
Location matters in RSV protection	99
“AHR-ming” host defense against cryptosporidiosis	99
Gut IgA: Never fear, the super inducers are here	97
A single-cell liver atlas of Plasmodium vivax infection	96
Cryptosporidium rhoptry effector protein ROP1 injected during invasion targets the host cytoskeletal modulator LMO7	95
Predator-prey interplay: When chemical conversation turns deadly	94
Decline in nitrosative stress drives antibiotic persister regrowth during infection	93
Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease	93
Antibiotics fire up inflammation to cool vaccine responsiveness	93
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids	91
One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome	91
Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster	91
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis	91
Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein	90
Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism	90
Dietary environmental factors shape the immune defense against Cryptosporidium infection	90
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection	90
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes	89
Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites	89
Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.2	89
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	87
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation	86
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA	85
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding	85
Goodbye PAM: Phage λ’s Red recombination system cripples PAMs and helps dodge CRISPR attacks	82
A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut	82
A counterintuitive antibody cocktail disrupts coxsackievirus	82

Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection	82
When NOD ligands become antidotes	80
Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins	79
Brain development in premature infants: A bug in the programming system?	78
GOSpel for tiny allies	78
Multi-arming ourselves against drug-resistant bacteria	77
Bacteria exploit viral dormancy to establish CRISPR-Cas immunity	76
The gut microbiome molecular complex in human health and disease	75
On track to tackle dengue: History and future of NS4B ligands	72
The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome	72
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease	72
A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases	71
Infant gut DNA bacteriophage strain persistence during the first 3 years of life	70
Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma	70
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome	70
Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system	70
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox	69
Enteric virome negatively affects seroconversion following oral rotavirus vaccination in a longitudinally sampled cohort of Ghanaian infants	69
Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2	69
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota	68
Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses	68
Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses	67
Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption	67
Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS	66
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease	66
AI in microbiome research: Where have we been, where are we going?	65
E. coli prophages encode an arsenal of defense systems to protect against temperate phages	65
Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer	65
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway	65
Methylglyoxal is an antibacterial effector produced by macrophages during infection	65
Unclouding Clostridiodes difficile virulence with systems biology	64
Cutibacterium acnes evolution: One pore at a time	64
Thanks, but no thanks: Cholera pathogen keeps incoming DNA at bay	64
“Indole-gence” for the mind	62
Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity	62
Metabolic cross-feeding of a dietary antioxidant enhances anaerobic energy metabolism by human gut bacteria	61
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity	61
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation	61
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission	61
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13	60
Commensal microbe regulation of skin cells in disease	60
Predictive regulatory and metabolic network models for systems analysis of Clostridioides difficile	60
Gut microbiome development and childhood undernutrition	60
An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer	58
Host-microbe interaction paradigms in acute and recurrent vulvovaginal candidiasis	57
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine	57
Rethinking healthy eating in light of the gut microbiome	56
Microbial Cgr2 will let your Th17 cells ROR(γT)	56
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions	56
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease	56
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage	55
Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy	55
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut	55
Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes	54
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization	54
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history	54
Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses	54
Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden	52
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species	51
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring	51
Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis	51
Even old foes can learn sweet new tricks	51
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites	51
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis	51
Growing up: A NOD2 our microbes	50
A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants	50
The gut-brain axis goes viral	50
Linking E. coli to fibrosis in Crohn’s disease	49
MAMPs: A devil tamed becomes an angel	49
Viral mimicry protects from infection when you’re expecting	48
Walking down the phosphorylation path to root immunity	48
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	48
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	47
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	47
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	47
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	46
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response	46
Multi-armed antibiotics for Gram-positive bacteria	46
Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	46
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	46

Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes	45
Going viral: The role of mobile genetic elements in bacterial immunity	45
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	45
A. baumannii’s nutrient tug-of-war	45
A colon cancer “prequel”	44
An expanded arsenal of immune systems that protect bacteria from phages	44
Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma	44
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	44
Stoking inflammasome fires in the COVID-19 neighborhood	44
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	44
HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization	43
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus	43
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis	42
Mimicry games: NPC-like MX2 condensates trap viruses	42
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	42
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?	42
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	42
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	42
Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics	41
Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides	41
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans	41
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	41
Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis	40
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	40
The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping	40
Pregnancy-associated morbidity and mortality during pandemics: Looking to the past in order to prepare for the future	39
The developing infant gut microbiome: A strain-level view	39
Compensating P. falciparum artemisinin resistance	39
Gut microbial enzymes and metabolic dysfunction-associated steatohepatitis: Function, mechanism, and therapeutic prospects	39
Bacteria renew an OLD protein to cleave host tRNAs and block phage translation	38
Bacterial molecular syringe for drug delivery	38
Oh, how we have grown!	37
A new piece of the microbiota pie: Mining ‘omics for DNA inversion states	37
It takes a plant village to raise a microbiome	37
Mg and the microbiome: A liver-protective duo	37
Differences in carbon metabolic capacity fuel co-existence and plasmid transfer between Salmonella strains in the mouse gut	36
Stitching together a healthy gut microbiome with fiber	36
Designing boosting immunogens for HIV-1 vaccine development	36
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein	36
Molecular basis for inhibition of type III-B CRISPR-Cas by an archaeal viral anti-CRISPR protein	36
Metagenomic selections reveal diverse antiphage defenses in human and environmental microbiomes	35
One size might fit all: Indole-3-propionic acid potentiates pan-cancer immunotherapy	35
BCG: From veins to correlates	35
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth	34
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont	34
RTS,S today and tomorrow’s science	34
Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens	33
Cryptosporidium modifies intestinal microvilli through an exported virulence factor	33
Charting a phage genome atlas	33
Sensing a pattern: Overlapping immunity in bacteria and eukaryotes	33
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity	33
A unique mode of nucleic acid immunity performed by a multifunctional bacterial enzyme	33
Networks of the symbiosis-immunity continuum in plants	33
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure	33
Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans	33
Won’t you be my neighbor? The importance of biogeography and nutrient niches in the gut	33
RNA editing of genomic neighbors controls antiviral response in fungi	33