Cell Host & Microbe

Article	Citations
Viral mimicry protects from infection when you’re expecting	984
Breathe and bloom: Gut hypoxia limits C. albicans growth	663
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	478
Secretory IgA: Linking microbes, maternal health, and infant health through human milk	474
Global, distinctive, and personal changes in molecular and microbial profiles by specific fibers in humans	469
Sowing the seeds of infection	336
Virus hunters: Discovering the evolutionary origins of SARS-CoV-2	311
Commensals make the most of their hosts	290
Trick and no treat: Carbohydrate preemption by commensal Enterobacteriaceae	279
Neutrophils flash their GLUTs to beat back detestable fungi	270
Even old foes can learn sweet new tricks	244
Salmonella “RecAmends” self-healing	229
Find a little help from my (microbial) friends	219
Norovirus cell tropism: The road to uncovering its secret hideout	208
Holding back: HLA-associated inhibition of NK cells gives HIV a leg up	203
The devil in the details: Herd immunity and pandemic response	192
From parent to progeny	174
A single-nucleotide polymorphism in Helicobacter pylori promotes gastric cancer development	170
From poo to promise: Fecal microbiota transplants support immunotherapy re-sensitization in solid tumors	170
Multi-armed antibiotics for Gram-positive bacteria	165
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes	164
Anatomy promotes neutral coexistence of strains in the human skin microbiome	154
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation	154
The gut-brain axis goes viral	139
Divide and conquer: Spatiotemporal plant innate immunity at single-cell resolution	132

The quest for control	132
Ecological diversity profiles of non-vaccine-targeted HPVs after gender-based community vaccination efforts	131
Salmonella-liberated dietary L-arabinose promotes expansion in superspreaders	130
Going viral: The role of mobile genetic elements in bacterial immunity	129
Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria	123
Linking E. coli to fibrosis in Crohn’s disease	118
Commensal fungi, a force to be reckoned with	116
Accelerating mammalian filovirus research with receptor binding blueprints	116
A Gpr35-tuned gut microbe-brain metabolic axis regulates depressive-like behavior	115
Engineered bacteria recycle tumor metabolic waste to boost immunotherapy	114
Fighting the invisible foe in cancer therapy	114
Salmonella Typhimurium expansion in the inflamed murine gut is dependent on aspartate derived from ROS-mediated microbiota lysis	113
Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller	111
Mommy’s microbes: Gestational diabetes mellitus shapes the maternal and infant gut microbiome	111
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19	108
Selenium nanoboosting of plant-beneficial microbiome	108
Walking down the phosphorylation path to root immunity	107
Type I IFN-mediated NET release promotes Mycobacterium tuberculosis replication and is associated with granuloma caseation	107
A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants	106
Early life host-microbe interactions in skin	106
Characterization of gut microbial structural variations as determinants of human bile acid metabolism	106
Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics	105
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	104
Direct comparison of antibody responses to four SARS-CoV-2 vaccines in Mongolia	103
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	103
Candida lipase packs a punch against IL-17	99
Loss of α-gal during primate evolution enhanced antibody-effector function and resistance to bacterial sepsis	97
Long-term evolution and short-term adaptation of microbiota strains and sub-strains in mice	95
Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1	93
HIV-infected macrophages resist efficient NK cell-mediated killing while preserving inflammatory cytokine responses	93
Argonaute-CLIP delineates versatile, functional RNAi networks in Aedes aegypti, a major vector of human viruses	93
Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies	91
Mycobacterium tuberculosis suppresses host DNA repair to boost its intracellular survival	90
Fungi make fun guys	89
Commensal microbiota regulates skin barrier function and repair via signaling through the aryl hydrocarbon receptor	89
Bacteroides acidifaciens drives a liver detox program	87
INDELible impact: How structural variants drive virulence and resistance	86
Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome	86
mRNA vaccines: A promising platform for safer, more effective next-generation Orthopoxvirus immunization	86
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	86
Gut commensal E. coli outer membrane proteins activate the host food digestive system through neural-immune communication	86
A large-scale type I CBASS antiphage screen identifies the phage prohead protease as a key determinant of immune activation and evasion	85
Colonization of the live biotherapeutic product VE303 and modulation of the microbiota and metabolites in healthy volunteers	85
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	85
An expanded arsenal of immune systems that protect bacteria from phages	84
Enteric VIP-producing neurons maintain gut microbiota homeostasis through regulating epithelium fucosylation	82
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes	81
MAMPs: A devil tamed becomes an angel	81
Persistent Salmonella infections in humans are associated with mutations in the BarA/SirA regulatory pathway	81
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	80

Phages and their satellites encode hotspots of antiviral systems	80
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	80
High-fat diet disrupts REG3γ and gut microbial rhythms promoting metabolic dysfunction	79
SARS-CoV-2 Omicron sublineages show comparable cell entry but differential neutralization by therapeutic antibodies	79
A short prokaryotic Argonaute activates membrane effector to confer antiviral defense	78
A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans	78
Mechanism of phage sensing and restriction by toxin-antitoxin-chaperone systems	77
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	75
A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1	74
Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	74
Stealth strategies of Candida albicans to evade host immunity	73
RNAi, a sword of plant seeds to combat viral infections	73
Multi-omics signatures reveal genomic and functional heterogeneity of Cutibacterium acnes in normal and diseased skin	73
Microbiome modification for personalized treatment of dysbiotic diseases	72
A prophage competition element protects Salmonella from lysis	71
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	71
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	71
A complex immune response to flagellin epitope variation in commensal communities	70
Longitudinal comparison of the developing gut virome in infants and their mothers	70
Evolutionarily conserved bacterial effectors hijack abscisic acid signaling to induce an aqueous environment in the apoplast	70
Enhanced neutralization resistance of SARS-CoV-2 Omicron subvariants BQ.1, BQ.1.1, BA.4.6, BF.7, and BA.2.75.2	69
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	69
An atlas of continuous adaptive evolution in endemic human viruses	69
Epithelial hypoxia maintains colonization resistance against Candida albicans	68
Candidalysin: An unlikely aide for fungal gut commensalism	68
Combatting superbugs using the evolutionary record of microbial warfare	67
Rapid design of bacteriophage cocktails to suppress the burden and virulence of gut-resident carbapenem-resistant Klebsiella pneumoniae	67
Opposing diet, microbiome, and metabolite mechanisms regulate inflammatory bowel disease in a genetically susceptible host	66
Interaction between Staphylococcus Agr virulence and neutrophils regulates pathogen expansion in the skin	64
Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation	64
Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating	64
Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization	64
Precision microbial intervention improves social behavior but not autism severity: A pilot double-blind randomized placebo-controlled trial	63
Rethinking phage-bacteria-eukaryotic relationships and their influence on human health	63
Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease	63
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response	63
Assessing phage-host population dynamics by reintroducing virulent viruses to synthetic microbiomes	62
Worming into infancy: Exploring helminth-microbiome interactions in early life	61
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	61
Developmental trajectory of the healthy human gut microbiota during the first 5 years of life	60
Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response	60
Detect and destroy: CRISPR-based technologies for the response against viruses	59
Signatures of antagonistic pleiotropy in a bacterial flagellin epitope	59
Prophages encode phage-defense systems with cognate self-immunity	59
Virus vaccines: proteins prefer prolines	59
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	58
Fiber-deficient diets reprogram the microbiota	57
Establishment and characterization of stable, diverse, fecal-derived in vitro microbial communities that model the intestinal microbiota	57
Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria	55
Microbial genome mining expedition unearths trove of antiviral defenses	55
Fecal matters: Microbial signatures distinguish clinically relevant subtypes of precancerous colorectal polyps	55
Gut commensals expand vitamin A metabolic capacity of the mammalian host	55
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	54
Identification of host regulators of Mycobacterium tuberculosis phenotypes uncovers a role for the MMGT1-GPR156 lipid droplet axis in persistence	54
Growing up: A NOD2 our microbes	54
Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode	54
Human cytomegalovirus degrades DMXL1 to inhibit autophagy, lysosomal acidification, and viral assembly	53
The dominoes fall after long-term antibiotic exposure	52
The blue-light receptor CRY1 serves as a switch to balance photosynthesis and plant defense	52
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	52
Trained immunity: Target for prophylaxis and therapy	52
Stress-induced condensate switch awakens sleeping viruses	52
A necrotizing toxin enables Pseudomonas syringae infection across evolutionarily divergent plants	51
MFSD6 is an entry receptor for respiratory enterovirus D68	51
Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection	50
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	50
Invade to evade: E. coli’s gutsy survival strategies	49
E. coli enhance colonization resistance against Salmonella Typhimurium by competing for galactitol, a context-dependent limiting carbon source	49
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus	49
Road to the discovery of HO-2’s myristate binding activity	47
A selfish bacteriocin dictates pneumococcal domination	47
A colon cancer “prequel”	47
Thymidine starvation promotes c-di-AMP-dependent inflammation during pathogenic bacterial infection	47
Antiviral RNA interference inhibits virus vertical transmission in plants	46
Antibacterial action, proteolytic immunity, and in vivo activity of a Vibrio cholerae microcin	46
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	45
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	45
Robbing the thief	45
Beta-carbolines suppress vaginal inflammation	45
A bacterial bile acid metabolite modulates Treg activity through the nuclear hormone receptor NR4A1	44

Gut microbiome ADP-ribosyltransferases are widespread phage-encoded fitness factors	44
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis	44
H19 influenza A virus exhibits species-specific MHC class II receptor usage	43
Two-for-one: Dual host-microbe functions of S. epidermidis Sph	43
Hair of the mouse: A skin bacteria “cocktail” gets follicles back on their feet	43
Antibiotic treatment ignites a fire that lasts	42
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?	42
SnapShot: The Expobiome Map	41
Helminths are positively AMPing up gut de-bugging	40
Help from commensals: β-hex to regulate gut immunity	40
The role of trained immunity in COVID-19: Lessons for the next pandemic	39
Immune activation kickstarts the gut microbiota	39
Select symbionts drive high IgA levels in the mouse intestine	38
Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection	38
The butterfly effect of the strain richness influences the efficacy of microbiota transplantation	38
Diet leaves a genetic signature in a keystone member of the gut microbiota	38
Protection against Clostridioides difficile disease by a naturally avirulent strain	38
Candida albicans accelerates atherosclerosis by activating intestinal hypoxia-inducible factor2α signaling	38
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant	38
Bugs take the sting out	38
Gut microbiome and bladder cancer: A new link through nitrosamine metabolism	37
Lessons learned by an organic chemist entering the microbiome field	37
A layered effect in bacterial defense	37
Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway	37
How do bacteria transform plants into their oasis?	37
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	37
Fatty liver? Microbiome sphingolipids to the rescue	36
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	36
Human influenza virus challenge identifies cellular correlates of protection for oral vaccination	35
Butyrate-producing Eubacterium rectale suppresses lymphomagenesis by alleviating the TNF-induced TLR4/MyD88/NF-κB axis	35
From top to bottom: Staphylococci in atopic dermatitis	35
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans	34
Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics	34
Large-scale phage cultivation for commensal human gut bacteria	33
Human milk nutrient fortifiers alter the developing gastrointestinal microbiota of very-low-birth-weight infants	33
Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75	33
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	33
Infant gut microbiota contributes to cognitive performance in mice	33
Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning	33
Global mapping of Salmonella enterica-host protein-protein interactions during infection	33
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics	32
Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides	32
Airway T cells are a correlate of i.v. Bacille Calmette-Guerin-mediated protection against tuberculosis in rhesus macaques	32
Regulators of male and female sexual development are critical for the transmission of a malaria parasite	32
Guilds as guides for health vs. disease	32
Duffy antigen is expressed during erythropoiesis in Duffy-negative individuals	32
Multi-omics reveal microbial determinants impacting responses to biologic therapies in inflammatory bowel disease	32
tHIS way to cognitive development	32
The developing infant gut microbiome: A strain-level view	32
Interferons in coronavirus pathogenesis: The good, the bad, and the ugly	31
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry	31
A lncRNA fine-tunes salicylic acid biosynthesis to balance plant immunity and growth	31
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	31