Cell Host & Microbe

Article	Citations
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes	491
Sowing the seeds of infection	487
Candidalysin: An unlikely aide for fungal gut commensalism	477
Combatting superbugs using the evolutionary record of microbial warfare	436
Microbial genome mining expedition unearths trove of antiviral defenses	300
Breathe and bloom: Gut hypoxia limits C. albicans growth	283
Engineered bacteria recycle tumor metabolic waste to boost immunotherapy	263
Selenium nanoboosting of plant-beneficial microbiome	259
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation	238
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	226
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	218
Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria	190
Epithelial hypoxia maintains colonization resistance against Candida albicans	182
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	181
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	180
MFSD6 is an entry receptor for respiratory enterovirus D68	174
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	172
Secretory IgA: Linking microbes, maternal health, and infant health through human milk	161
Cad1 turns ATP into phage poison	159
Help from commensals: β-hex to regulate gut immunity	151
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry	148
Immunity to fungi and vaccine considerations	147
A broadly distributed predicted helicase/nuclease confers phage resistance via abortive infection	145
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome	144
Two-for-one: Dual host-microbe functions of S. epidermidis Sph	144

Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant	143
From top to bottom: Staphylococci in atopic dermatitis	141
Select symbionts drive high IgA levels in the mouse intestine	141
There and back again: Discovering antiviral and antiphage defenses using deep homology	136
Tactical terminase: How a Salmonella prophage navigates oxidative stress	132
Beta-carbolines suppress vaginal inflammation	129
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	126
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	125
Antibiotic treatment ignites a fire that lasts	123
Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes	121
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis	121
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics	120
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding	118
Overcoming drug resistance, the natural way	118
A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut	118
Modulating HIV-1 envelope glycoprotein conformation to decrease the HIV-1 reservoir	118
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	118
Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism	117
Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster	117
Dietary environmental factors shape the immune defense against Cryptosporidium infection	116
Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis	115
Cryptosporidium rhoptry effector protein ROP1 injected during invasion targets the host cytoskeletal modulator LMO7	110
A single-cell liver atlas of Plasmodium vivax infection	109
The gut microbiome: Bridging medications and clinical outcomes post stem cell transplantation	108
Decline in nitrosative stress drives antibiotic persister regrowth during infection	108
Location matters in RSV protection	108
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation	108
A lung pathobiont story: Thinking outside the Koch’s postulate box	107
“AHR-ming” host defense against cryptosporidiosis	107
Gut IgA: Never fear, the super inducers are here	102
Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity	102
One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome	99
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids	98
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection	98
Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection	96
Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein	94
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes	92
Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites	92
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA	91
Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease	91
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis	90
Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.2	90
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota	89
Goodbye PAM: Phage λ’s Red recombination system cripples PAMs and helps dodge CRISPR attacks	88
Bacteria exploit viral dormancy to establish CRISPR-Cas immunity	87
When NOD ligands become antidotes	87
A counterintuitive antibody cocktail disrupts coxsackievirus	87
Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins	86
Multi-arming ourselves against drug-resistant bacteria	85
A phingerprint for rheumatoid arthritis development?	84

Brain development in premature infants: A bug in the programming system?	83
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease	83
Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma	81
Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses	81
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome	80
AI in microbiome research: Where have we been, where are we going?	79
The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome	78
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox	77
Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS	77
On track to tackle dengue: History and future of NS4B ligands	76
GOSpel for tiny allies	76
Enteric virome negatively affects seroconversion following oral rotavirus vaccination in a longitudinally sampled cohort of Ghanaian infants	75
The gut microbiome molecular complex in human health and disease	75
Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption	75
A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases	74
Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses	74
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease	74
Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer	74
Infant gut DNA bacteriophage strain persistence during the first 3 years of life	74
Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2	73
Unclouding Clostridiodes difficile virulence with systems biology	72
Thanks, but no thanks: Cholera pathogen keeps incoming DNA at bay	71
“Indole-gence” for the mind	71
Cutibacterium acnes evolution: One pore at a time	71
Commensal microbe regulation of skin cells in disease	70
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission	69
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation	68
Predictive regulatory and metabolic network models for systems analysis of Clostridioides difficile	67
Gut microbiome development and childhood undernutrition	67
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13	66
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions	66
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine	65
Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis	65
An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer	64
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity	64
Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity	64
Enteric viruses seize their immunomodulatory niche	63
Rethinking healthy eating in light of the gut microbiome	63
Microbial Cgr2 will let your Th17 cells ROR(γT)	63
Host-microbe interaction paradigms in acute and recurrent vulvovaginal candidiasis	63
Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy	62
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species	62
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring	62
Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome	61
Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes	61
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut	60
Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses	60
Global COVID-19 vaccine inequity: The scope, the impact, and the challenges	60
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis	59
Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden	59
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization	59
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage	57
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites	57
Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis	57
The gut-brain axis goes viral	56
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history	56
Viral mimicry protects from infection when you’re expecting	55
Even old foes can learn sweet new tricks	55
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	55
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	54
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response	53
Growing up: A NOD2 our microbes	53
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	53
Walking down the phosphorylation path to root immunity	52
Linking E. coli to fibrosis in Crohn’s disease	52
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	52
MAMPs: A devil tamed becomes an angel	52
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	51
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	51
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes	51
Going viral: The role of mobile genetic elements in bacterial immunity	51
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	51
Multi-armed antibiotics for Gram-positive bacteria	50
Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	49
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	49
A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants	49
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	49
Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization	47
An expanded arsenal of immune systems that protect bacteria from phages	47
License to LAP	47

A colon cancer “prequel”	47
Stoking inflammasome fires in the COVID-19 neighborhood	47
HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization	46
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?	46
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	46
Recording of DNA-binding events reveals the importance of a repurposed Candida albicans regulatory network for gut commensalism	46
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis	45
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	45
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	45
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	44
The developing infant gut microbiome: A strain-level view	44
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus	44
Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis	44
Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides	43
Mimicry games: NPC-like MX2 condensates trap viruses	43
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	43
The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping	43
Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics	43
Compensating P. falciparum artemisinin resistance	42
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans	42
Pregnancy-associated morbidity and mortality during pandemics: Looking to the past in order to prepare for the future	42
Bacteria renew an OLD protein to cleave host tRNAs and block phage translation	41
Bacterial molecular syringe for drug delivery	41
A new piece of the microbiota pie: Mining ‘omics for DNA inversion states	40
Designing boosting immunogens for HIV-1 vaccine development	40
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth	40
Mg and the microbiome: A liver-protective duo	40
RTS,S today and tomorrow’s science	39
It takes a plant village to raise a microbiome	39
Stitching together a healthy gut microbiome with fiber	39
One size might fit all: Indole-3-propionic acid potentiates pan-cancer immunotherapy	39
Oh, how we have grown!	39
Molecular basis for inhibition of type III-B CRISPR-Cas by an archaeal viral anti-CRISPR protein	38
Differences in carbon metabolic capacity fuel co-existence and plasmid transfer between Salmonella strains in the mouse gut	38
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure	38
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein	37
BCG: From veins to correlates	37
Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans	37
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont	37
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity	37
Won’t you be my neighbor? The importance of biogeography and nutrient niches in the gut	37
Fishing for obesity-related gut microbiome enterotype	36
Happy families	36
Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies	36
Sensing a pattern: Overlapping immunity in bacteria and eukaryotes	36
Host hepatic metabolism is modulated by gut microbiota-derived sphingolipids	36
Long live the king: Toxoplasma gondii nucleomodulin inhibits necroptotic cell death	36
Mechanisms of bacterial immunity, protection, and survival during interbacterial warfare	36
RNA editing of genomic neighbors controls antiviral response in fungi	35
A unique mode of nucleic acid immunity performed by a multifunctional bacterial enzyme	35
Bacterial defense systems exhibit synergistic anti-phage activity	35
Gut microbiome and necrotizing enterocolitis: Understanding the connection to find a cure	35
Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut	34
Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens	34
Cryptosporidium modifies intestinal microvilli through an exported virulence factor	34
What E. coli knows about your 1-year-old infant: Antibiotic use, lifestyle, birth mode, and siblings	34
Symbiont-regulated serotonin biosynthesis modulates tick feeding activity	33
Unleashing natural antibodies against HIV-1	33
Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis	33
Human gut bacterial metabolism drives Th17 activation and colitis	33
COVID-19 as a catalyst for vaccine manufacturing: A South African experience	32
Meta-organismal metabolism in cardiovascular disease	32
Bug in the code: TB blocks DNA repair	32
Stress less: Viral mastery of the RNA G-quadruplex	31
Whack-a-virus: HIV-specific T cells play an exhausting game	31
Microbiomes in Neverland	31
Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps	31
Taking the pulse: Bacterial responses to intermittent antibiotics	31
Persisting uropathogenic Escherichia coli lineages show signatures of niche-specific within-host adaptation mediated by mobile genetic elements	30
Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin	30
Prospects for preventing cancer with anti-microbial prophylactic vaccines	30
Unbiased discovery of natural sequence variants that influence fungal virulence	30
Neutrophil recruitment during intestinal inflammation primes Salmonella elimination by commensal E. coli in a context-dependent manner	30
Arresting microbiome development limits immune system maturation and resistance to infection in mice	30
Lactobacillus reuteri joins the liver autoimmune arena	29
Sugar transporters spatially organize microbiota colonization along the longitudinal root axis of Arabidopsis	29
Vivax malaria and Duffy antigen: Stop being so negative	29
A tough act to swallow: Streptococcus anginosus and gastric cancer	29
SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns	28
Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses	28
Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2	28
Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals	28
Paneth cell TNF signaling induces gut bacterial translocation and sepsis	28
Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis	28
Turning CRISPR on with antibiotics	27
Heritable oral microbes and their importance in microbiome research for public health	27
Diet, microbe, and autism: Cause or consequence?	27
Host-microbe circadian dynamics: Finding a rhythm and hitting a groove in scientific inquiry	27
Microbial seeding in early life	27
BlpC-mediated selfish program leads to rapid loss of Streptococcus pneumoniae clonal diversity during infection	27
Biomarker-responsive engineered probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice	27
T cell reactivity to Bordetella pertussis is highly diverse regardless of childhood vaccination	26
Neisseria species as pathobionts in bronchiectasis	26
Putting the p(hosphor) in pyroptosis	26
Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections	26