Interdisciplinary Sciences-Computational Life Sciences

Article	Citations
Unraveling Brain Synchronisation Dynamics by Explainable Neural Networks using EEG Signals: Application to Dyslexia Diagnosis	158
OTNet: A CNN Method Based on Hierarchical Attention Maps for Grading Arteriosclerosis of Fundus Images with Small Samples	123
DP-ID: Interleaving and Denoising to Improve the Quality of DNA Storage Image	55
Construction of a Pearson- and MIC-Based Co-expression Network to Identify Potential Cancer Genes	55
Deep Clustering-Based Metabolic Stratification of Non-Small Cell Lung Cancer Patients Through Integration of Somatic Mutation Profile and Network Propagation Algorithm	45
PDDGCN: A Parasitic Disease–Drug Association Predictor Based on Multi-view Fusion Graph Convolutional Network	45
ResDeepSurv: A Survival Model for Deep Neural Networks Based on Residual Blocks and Self-attention Mechanism	45
CA-UNet Segmentation Makes a Good Ischemic Stroke Risk Prediction	43
Metapath-Based Deep Convolutional Neural Network for Predicting miRNA-Target Association on Heterogeneous Network	37
Computational Study of Methionine Methylation Process Catalyzed by SETD3	37
An Integrated TCN-CrossMHA Model for Predicting circRNA-RBP Binding Sites	32
Differential Diagnosis of DCIS and Fibroadenoma Based on Ultrasound Images: a Difference-Based Self-Supervised Approach	31
Cervical Cancer Classification From Pap Smear Images Using Deep Convolutional Neural Network Models	29
Cell Fate Dynamics Reconstruction Identifies TPT1 and PTPRZ1 Feedback Loops as Master Regulators of Differentiation in Pediatric Glioblastoma-Immune Cell Networks	25
Identifying Lymph Node Metastasis-Related Factors in Breast Cancer Using Differential Modular and Mutational Structural Analysis	22
Diagnosis of Pancreatic Cancer Using miRNA30e Biosensor	21
Machine Learning Accelerates De Novo Design of Antimicrobial Peptides	21
A Domain Adaptive Interpretable Substructure-Aware Graph Attention Network for Drug–Drug Interaction Prediction	21
BiGM-lncLoc: Bi-level Multi-Graph Meta-Learning for Predicting Cell-Specific Long Noncoding RNAs Subcellular Localization	20
Developing a Novel Methodology by Integrating Deep Learning and HMM for Segmentation of Retinal Blood Vessels in Fundus Images	20
Adaptive Multi-Kernel Graph Neural Network for Drug-Drug Interaction Prediction	19
dbMisLoc: A Manually Curated Database of Conditional Protein Mis-localization Events	18
Development of Electrochemical Biosensor for miR204-Based Cancer Diagnosis	17
Development of an Expert-Level Right Ventricular Abnormality Detection Algorithm Based on Deep Learning	16
Predicting circRNA-Disease Associations Based on Deep Matrix Factorization with Multi-source Fusion	16

EfficientNet-resDDSC: A Hybrid Deep Learning Model Integrating Residual Blocks and Dilated Convolutions for Inferring Gene Causality in Single-Cell Data	16
A Multi-view Molecular Pre-training with Generative Contrastive Learning	15
Single-Cell Transcriptome Analysis Reveals the Role of Pancreatic Secretome in COVID-19 Associated Multi-organ Dysfunctions	15
A Hierarchical Error Correction Strategy for Text DNA Storage	14
CR-deal: Explainable Neural Network for circRNA-RBP Binding Site Recognition and Interpretation	13
scEM: A New Ensemble Framework for Predicting Cell Type Composition Based on scRNA-Seq Data	12
Drug Sensitivity Prediction Based on Multi-stage Multi-modal Drug Representation Learning	12
Transformative Deep Neural Network Approaches in Kidney Ultrasound Segmentation: Empirical Validation with an Annotated Dataset	12
Exploring Novel Fentanyl Analogues Using a Graph-Based Transformer Model	12
scVAEBGM: Clustering Analysis of Single-Cell ATAC-seq Data Using a Deep Generative Model	11
Protein Multiple Conformation Prediction Using Multi-Objective Evolution Algorithm	11
Review of Progress in Diagnostic Studies of Autism Spectrum Disorder Using Neuroimaging	10
Exploring the Molecular Basis of Substrate and Product Selectivities of Nocardicin Bifunctional Thioesterase	10
DCDA: CircRNA–Disease Association Prediction with Feed-Forward Neural Network and Deep Autoencoder	10
Plant lncRNA-miRNA Interaction Prediction Based on Counterfactual Heterogeneous Graph Attention Network	10
Correction to: Machine Learning Accelerates De Novo Design of Antimicrobial Peptides	10
Integrating Protein–Protein Interaction Networks and Somatic Mutation Data to Detect Driver Modules in Pan-Cancer	9
Improving the Prediction of Potential Kinase Inhibitors with Feature Learning on Multisource Knowledge	9
A Review of Parallel Implementations for the Smith–Waterman Algorithm	9
Semantic Consistency Network with Edge Learner and Connectivity Enhancer for Cervical Tumor Segmentation from Histopathology Images	9
easyMF: A Web Platform for Matrix Factorization-Based Gene Discovery from Large-scale Transcriptome Data	9
Biomarker Identification in Membranous Nephropathy Using a Long Non-coding RNA-Mediated Competitive Endogenous RNA Network	9
Prediction of Protein Solubility Based on Sequence Feature Fusion and DDcCNN	9
IHDFN-DTI: Interpretable Hybrid Deep Feature Fusion Network for Drug–Target Interaction Prediction	8
SMART v1.0: A Database for Small Molecules with Functional Implications in Plants	8
Classification of Glomerular Pathology Images in Children Using Convolutional Neural Networks with Improved SE-ResNet Module	8
DOTAD: A Database of Therapeutic Antibody Developability	8
PredAPP: Predicting Anti-Parasitic Peptides with Undersampling and Ensemble Approaches	8
BMRI-NET: A Deep Stacked Ensemble Model for Multi-class Brain Tumor Classification from MRI Images	8
MVGCNMDA: Multi-view Graph Augmentation Convolutional Network for Uncovering Disease-Related Microbes	8
Correction to: HD5 and LL‑37 Inhibit SARS‑CoV and SARS‑CoV‑2 Binding to Human ACE2 by Molecular Simulation	8
In Silico Mutagenesis-Based Remodelling of SARS-CoV-1 Peptide (ATLQAIAS) to Inhibit SARS-CoV-2: Structural-Dynamics and Free Energy Calculations	7
RicENN: Prediction of Rice Enhancers with Neural Network Based on DNA Sequences	7
Identifying Protein Phosphorylation Site-Disease Associations Based on Multi-Similarity Fusion and Negative Sample Selection by Convolutional Neural Network	7
The Application of Convolutional Neural Network Model in Diagnosis and Nursing of MR Imaging in Alzheimer's Disease	7
PmliHFM: Predicting Plant miRNA-lncRNA Interactions with Hybrid Feature Mining Network	7
IDDLncLoc: Subcellular Localization of LncRNAs Based on a Framework for Imbalanced Data Distributions	7
A Novel Deep Learning Model for Medical Image Segmentation with Convolutional Neural Network and Transformer	7
CRBP-HFEF: Prediction of RBP-Binding Sites on circRNAs Based on Hierarchical Feature Expansion and Fusion	7
Dual Attention Mechanisms and Feature Fusion Networks Based Method for Predicting LncRNA-Disease Associations	7
CHL-DTI: A Novel High–Low Order Information Convergence Framework for Effective Drug–Target Interaction Prediction	7
Multi-kernel Learning Fusion Algorithm Based on RNN and GRU for ASD Diagnosis and Pathogenic Brain Region Extraction	7
In silico Methods for Identification of Potential Therapeutic Targets	7
iAmyP: A Multi-view Learning for Amyloidogenic Hexapeptides Identification Based on Sequence Least Squares Programming	7
MTGGF: A Metabolism Type-Aware Graph Generative Model for Molecular Metabolite Prediction	7
NPI-HGNN: A Heterogeneous Graph Neural Network-Based Approach for Predicting ncRNA-Protein Interactions	6
Similarity and Dissimilarity Regularized Nonnegative Matrix Factorization for Single-Cell RNA-seq Analysis	6
Design and Simulation of an Autonomous Molecular Mechanism Using Spatially Localized DNA Computation	6
scRDiT: Generating Single-cell RNA-seq Data by Diffusion Transformers and Accelerating Sampling	6
Combining Global-Constrained Concept Factorization and a Regularized Gaussian Graphical Model for Clustering Single-Cell RNA-seq Data	6

CD47Binder: Identify CD47 Binding Peptides by Combining Next-Generation Phage Display Data and Multiple Peptide Descriptors	6
Predicting Drug Synergy and Discovering New Drug Combinations Based on a Graph Autoencoder and Convolutional Neural Network	6
RNA Folding Based on 5 Beads Model and Multiscale Simulation	6
Complex Prediction in Large PPI Networks Using Expansion and Stripe of Core Cliques	6
Discovery of a Natural Product with Potent Efficacy Against SARS-CoV-2 by Drug Screening	6
AMPFLDAP: Adaptive Message Passing and Feature Fusion on Heterogeneous Network for LncRNA-Disease Associations Prediction	6
Reinforced Collaborative-Competitive Representation for Biomedical Image Recognition	6
Efficient Storage and Analysis of Genomic Data: A k-mer Frequency Mapping and Image Representation Method	6
EPI-Mind: Identifying Enhancer–Promoter Interactions Based on Transformer Mechanism	6
PredPromoter-MF(2L): A Novel Approach of Promoter Prediction Based on Multi-source Feature Fusion and Deep Forest	5
Pathogenic Factors Identification of Brain Imaging and Gene in Late Mild Cognitive Impairment	5
Multi-feature Fusion Method Based on Linear Neighborhood Propagation Predict Plant LncRNA–Protein Interactions	5
Visualizing a Field of Research for the Coronavirus Replication in Humans with Knowledge Mapping: Evidence from Web of Science	5
Predicting Protein–Ligand Binding Affinity Using Fusion Model of Spatial-Temporal Graph Neural Network and 3D Structure-Based Complex Graph	5
BoT-Net: a lightweight bag of tricks-based neural network for efficient LncRNA–miRNA interaction prediction	5
Bilinear Perceptual Fusion Algorithm Based on Brain Functional and Structural Data for ASD Diagnosis and Regions of Interest Identification	5
A Self-attention Graph Convolutional Network for Precision Multi-tumor Early Diagnostics with DNA Methylation Data	5
A Multi-perspective Model for Protein–Ligand-Binding Affinity Prediction	5
DeepPI: Alignment-Free Analysis of Flexible Length Proteins Based on Deep Learning and Image Generator	5
sORFPred: A Method Based on Comprehensive Features and Ensemble Learning to Predict the sORFs in Plant LncRNAs	4
Identification of Type II Toxin-Antitoxin Loci in Levilactobacillus brevis	4
FTWSVM-SR: DNA-Binding Proteins Identification via Fuzzy Twin Support Vector Machines on Self-Representation	4
SeFilter-DIA: Squeeze-and-Excitation Network for Filtering High-Confidence Peptides of Data-Independent Acquisition Proteomics	4
DASNet: A Convolutional Neural Network with SE Attention Mechanism for ccRCC Tumor Grading	4
Viral Rebound After Antiviral Treatment: A Mathematical Modeling Study of the Role of Antiviral Mechanism of Action	4
Adap-BDCM: Adaptive Bilinear Dynamic Cascade Model for Classification Tasks on CNV Datasets	4
Correction to: Brain Tumor Detection and Classification Using Cycle Generative Adversarial Networks	4
CSEL-BGC: A Bioinformatics Framework Integrating Machine Learning for Defining the Biosynthetic Evolutionary Landscape of Uncharacterized Antibacterial Natural Products	4
WDGBANDTI: A Deep Graph Convolutional Network-Based Bilinear Attention Network for Drug-Target Interaction Prediction with Domain Adaptation	4
BMPMDA: Prediction of MiRNA-Disease Associations Using a Space Projection Model Based on Block Matrix	4
Machine Learning Applications in Drug Repurposing	4
Lung Cancer Detection and Improving Accuracy Using Linear Subspace Image Classification Algorithm	3
ScAGCN: Graph Convolutional Network with Adaptive Aggregation Mechanism for scRNA-seq Data Dimensionality Reduction	3
Deep Learning-Based Modeling of Drug–Target Interaction Prediction Incorporating Binding Site Information of Proteins	3
Enabling Artificial Intelligence for Genome Sequence Analysis of COVID-19 and Alike Viruses	3
Empowering Graph Neural Network-Based Computational Drug Repositioning with Large Language Model-Inferred Knowledge Representation	3
Improving language model of human genome for DNA–protein binding prediction based on task-specific pre-training	3
PDBms—An online tool for PDB file splitting and interactive molecular visualization	3
RSCMDA: Prediction of Potential miRNA–Disease Associations Based on a Robust Similarity Constraint Learning Method	3
MetaV: A Pioneer in feature Augmented Meta-Learning Based Vision Transformer for Medical Image Classification	3
GEnDDn: An lncRNA–Disease Association Identification Framework Based on Dual-Net Neural Architecture and Deep Neural Network	3
Reconstructing Waddington Landscape from Cell Migration and Proliferation	3
Identify Modules Associated with Immunotherapy Response from Mouse Tumor Profiles for Stratifying Cancer Patients	3
Drug Repositioning Based on Deep Sparse Autoencoder and Drug–Disease Similarity	3
MF-MNER: Multi-models Fusion for MNER in Chinese Clinical Electronic Medical Records	3
TP-DDI: A Two-Pathway Deep Neural Network for Drug–Drug Interaction Prediction	3
Sequence-Based Prediction of Transmembrane Protein Crystallization Propensity	3
Multiple Protein Subcellular Locations Prediction Based on Deep Convolutional Neural Networks with Self-Attention Mechanism	3
LPCANet: Classification of Laryngeal Cancer Histopathological Images Using a CNN with Position Attention and Channel Attention Mechanisms	3
BES-Designer: A Web Tool to Design Guide RNAs for Base Editing to Simplify Library	3
Inferring Gene Regulatory Networks Using the Improved Markov Blanket Discovery Algorithm	3
FSCAM: CAM-Based Feature Selection for Clustering scRNA-seq	3
Application of Semi-supervised Fuzzy Clustering Based on Knowledge Weighting and Cluster Center Learning to Mammary Molybdenum Target Image Segmentation	3
LRT-CLUSTER: A New Clustering Algorithm Based on Likelihood Ratio Test to Identify Driving Genes	3
tensorGSEA: Detecting Differential Pathways in Type 2 Diabetes via Tensor-Based Data Reconstruction	3
Self-Supervised Graph Representation Learning for Single-Cell Classification	3
A Novel Detection Method for High-Order SNP Epistatic Interactions Based on Explicit-Encoding-Based Multitasking Harmony Search	3
LPI-SKMSC: Predicting LncRNA–Protein Interactions with Segmented k-mer Frequencies and Multi-space Clustering	3
SBTD: A Novel Method for Detecting Topological Associated Domains from Hi-C Data	2
Identifying Visual Attention Features Accurately Discerning Between Autism and Typically Developing: a Deep Learning Framework	2
Analysis of CRISPR-Cas Loci and their Targets in Levilactobacillus brevis	2
Computer-Aided Diagnosis of Complications After Liver Transplantation Based on Transfer Learning	2
Synchronous Mutual Learning Network and Asynchronous Multi-Scale Embedding Network for miRNA-Disease Association Prediction	2
A Combined Manual Annotation and Deep-Learning Natural Language Processing Study on Accurate Entity Extraction in Hereditary Disease Related Biomedical Literature	2
Identification of Benign and Malignant Lung Nodules in CT Images Based on Ensemble Learning Method	2
StoneNet: An Efficient Lightweight Model Based on Depthwise Separable Convolutions for Kidney Stone Detection from CT Images	2
Predicting CircRNA-Disease Associations Based on Heterogeneous Graph Neural Network and Knowledge Graph Attribute Mining Attention	2
A Deep Neural Network for Predicting Synergistic Drug Combinations on Cancer	2
GraphsformerCPI: Graph Transformer for Compound–Protein Interaction Prediction	2
Preclinical Western Blot in the Era of Digital Transformation and Reproducible Research, an Eastern Perspective	2
DSMR: Dual-Stream Networks with Refinement Module for Unsupervised Multi-modal Image Registration	2
Discovery of Genetic Biomarkers for Alzheimer’s Disease Using Adaptive Convolutional Neural Networks Ensemble and Genome-Wide Association Studies	2
A Novel Deep-Learning-Based CADx Architecture for Classification of Thyroid Nodules Using Ultrasound Images	2
ABTrans: A Transformer-based Model for Predicting Interaction between Anti-Aβ Antibodies and Peptides	2
U-shaped Retinal Vessel Segmentation Based on Adaptive Aggregation of Feature Information	2
Ensemble Machine Learning and Predicted Properties Promote Antimicrobial Peptide Identification	2
Sensing Compound Substructures Combined with Molecular Fingerprinting to Predict Drug-Target Interactions	2
ResNeXt-Based Rescoring Model for Proteoform Characterization in Top-Down Mass Spectra	2
Prediction of Potential MicroRNA–Disease Association Using Kernelized Bayesian Matrix Factorization	2
Cell Features Reconstruction from Gene Association Network of Single Cell	2

Automatic Detection of Covid-19 with Bidirectional LSTM Network Using Deep Features Extracted from Chest X-ray Images	2
misORFPred: A Novel Method to Mine Translatable sORFs in Plant Pri-miRNAs Using Enhanced Scalable k-mer and Dynamic Ensemble Voting Strategy	2
Rhythmic Component Analysis Tool (RCAT): A Precise, Efficient and User-Friendly Tool for Circadian Clock Genes Analysis	2
Using Network Distance Analysis to Predict lncRNA–miRNA Interactions	2
Clinical and Laboratory Approach to Diagnose COVID-19 Using Machine Learning	2
Identifiable Temporal Feature Selection via Horizontal Visibility Graph Towards Smart Medical Applications	2