Advances in Clinical and Experimental Medicine

Article	Citations
Cerebral small vessel disease: A review	97
Monitoring the kynurenine system: Concentrations, ratios or what else?	49
Neurobiological advances of learned fear in humans	45
Comparison of the clinical differences between COVID-19, SARS, influenza, and the common cold: A systematic literature review	36
Aging, depression and dementia: The inflammatory process	31
Recent advances in the study of the comorbidity of depressive and anxiety disorders	30
Preclinical modeling in depression and anxiety: Current challenges and future research directions	29
Acute kidney injury in patients with COVID-19: Epidemiology, pathogenesis and treatment	24
Advances in EEG-based functional connectivity approaches to the study of the central nervous system in health and disease	24
Diagnosis of type 1 diabetes during the SARS-CoV-2 pandemic: Does lockdown affect the incidence and clinical status of patients?	24
Applications for graphene and its derivatives in medical devices: Current knowledge and future applications	24
Lethal and life-limiting skeletal dysplasias: Selected prenatal issues	21
Arbutin inhibits inflammation and apoptosis by enhancing autophagy via SIRT1	21
Machine learning in orthodontics: Challenges and perspectives	21
Hematological manifestations and complications of COVID-19	21
Interleukin 6: biological significance and role in inflammatory bowel diseases	19
Baicalein modulates the radiosensitivity of cervical cancer cells in vitro via miR-183 and the JAK2/STAT3 signaling pathway	19
Paclitaxel inhibits proliferation and invasion and promotes apoptosis of breast cancer cells by blocking activation of the PI3K/AKT signaling pathway	18
CircHIPK3 promotes neuroinflammation through regulation of the miR-124-3p/STAT3/NLRP3 signaling pathway in Parkinson’s disease	18
Lecanemab (Leqembi) is not the right drug for patients with Alzheimer’s disease	17
Puerarin pretreatment inhibits myocardial apoptosis and improves cardiac function in rats after acute myocardial infarction through the PI3K/Akt signaling pathway	16
Intestinal amyloidosis: Clinical manifestations and diagnostic challenge	16
Stilbene glycoside upregulates SIRT3/AMPK to promotes neuronal mitochondrial autophagy and inhibit apoptosis in ischemic stroke	15
MiR-124 protects against cognitive dysfunction induced by sevoflurane anesthesia in vivo and in vitro through targeting calpain small subunit 1 via NF-κB signaling pathway	15
Crocin attenuates oxidative and inflammatory stress-related periodontitis in cardiac tissues in rats	14

Echinatin mitigates H2O2-induced oxidative damage and apoptosis in lens epithelial cells via the Nrf2/HO-1 pathway	14
Ganoderic acid A inhibits ox-LDL-induced THP-1-derived macrophage inflammation and lipid deposition via Notch1/PPARγ/CD36 signaling	14
LncRNA PCGEM1 mediates oxaliplatin resistance in hepatocellular carcinoma via miR-129-5p/ETV1 axis in vitro	13
Inflammation and diet: Focus on mental and cognitive health	13
LncRNA ANRIL negatively regulated chitooligosaccharide-induced radiosensitivity in colon cancer cells by sponging miR-181a-5p	13
Exosome EpCAM promotes the metastasis of glioma by targeting the CD44 signaling molecule on the surface of glioma cells	13
Evaluation of Er:YAG and Er,Cr:YSGG laser irradiation for the debonding of prefabricated zirconia crowns	13
Association between the long-term exposure to air pollution and depression	12
Investigation of the role of miR-221 in diabetic peripheral neuropathy and related molecular mechanisms	12
Ultrafiltration in acute heart failure: Current knowledge and fields for further research	12
Melatonin protected against myocardial infarction injury in rats through a Sirt6-dependent antioxidant pathway	11
The clinical value of high-density lipoprotein in the evaluation of new coronavirus pneumonia	11
The effect of taxifolin on high-dose-cisplatin-induced oxidative liver injury in rats	11
The intricate brain–body interaction in psychiatric and neurological diseases	11
EGCG decreases myocardial infarction in both I/R and MIRI rats through reducing intracellular Ca2+ and increasing TnT levels in cardiomyocytes	11
Laser dentistry in daily practice during the COVID-19 pandemic: Benefits, risks and recommendations for safe treatments	11
Therapeutic role of vanillin receptors in cancer	11
miR-874 ameliorates retinopathy in diabetic rats by NF-κB signaling pathway	11
LncRNA NORAD regulates scar hypertrophy via miRNA-26a mediating the regulation of TGFβR1/2	10
Wharton’s jelly-derived mesenchymal stem cells in the treatment of four patients with alopecia areata	10
Meta-analysis of the diagnostic value of procalcitonin in adult burn sepsis	10
Effectiveness of TI-RADS and ATA classifications for predicting malignancy of thyroid nodules	10
GLP-1 receptor agonists, polycystic ovary syndrome and reproductive dysfunction: Current research and future horizons	10
miR-124-3p targeting of TGF-β1 inhibits the proliferation of hypertrophic scar fibroblasts	9
Predictive factors in post-stroke epilepsy: Retrospective analysis	9
Phenotyping in heart failure with preserved ejection fraction: A key to find effective treatment	9
Effect of thiamine pyrophosphate on cyclophosphamide-induced oxidative ovarian damage and reproductive dysfunction in female rats	9
Oxidative and pro-inflammatory lung injury induced by desflurane inhalation in rats and the protective effect of rutin	9
Pharmacotherapeutic pain management in patients undergoing laparoscopic cholecystectomy: A review	9
Anticoagulant-related nephropathy: Focus on novel agents. A review	9
Cornelian cherry extract ameliorates osteoporosis associated with hypercholesterolemia in New Zealand rabbits	9
Infectious diseases of the skin in contact sports	9
Effect of adenosine triphosphate, benidipine and their combinations on bevacizumab-induced kidney damage in rats	9
A prognostic signature based on the expression profile of the ferroptosis-related long non-coding RNAs in hepatocellular carcinoma	9
CD147 promotes invasion and MMP-9 expression through MEK signaling and predicts poor prognosis in hypopharyngeal squamous cell carcinoma	9
Overexpression of GSTP1 promotes colorectal cancer cell proliferation, invasion and metastasis by upregulating STAT3	9
Influence of SARS-CoV-2 infection on thyroid gland function: The current knowledge	9
Impaired fertility in women and men with chronic kidney disease	8
Recent advances in the study of the neurobiological mechanisms behind the effects of physical activity on mood, resilience and emotional disorders	8
MYBL2 in synergy with CDC20 promotes the proliferation and inhibits apoptosis of gastric cancer cells	8
Prediction of prognosis in sepsis patients by the SOFA score combined with miR-150	8
Non-secretory multiple myeloma: Diagnosis and management	8
The effectiveness of methotrexate and low-dose steroid therapy in the treatment of idiopathic granulomatous mastitis	8
Soluble syndecan-1 as marker of intestinal inflammation: A preliminary study and evaluation of a new panel of biomarkers for non-invasive prediction of active ulcerative colitis	8
Relationships between circulating galectin-3, extracellular matrix fibrosis and outcomes in dilated cardiomyopathy	8
Dualistic role of autophagy in cancer progression	8
Cancer patients and internal medicine patients attitude towards COVID-19 vaccination in Poland	8
Three cases of 3β-hydroxysteroid dehydrogenase deficiency: Clinical analysis	8
Effects of calcium electroporation, electrochemotherapy, and irreversible electroporation on quality of life and progression-free survival in patients with pancreatic cancer: IREC clinical study	8
lncRNA PSMA3-AS1 promotes the progression of non-small cell lung cancer through targeting miR-17-5p/PD-L1	8

Comparison of a manual walking platform and the CatWalk gait analysis system in a rat osteoarthritis model	7
Basal cell carcinoma secondary to trauma: A 3-year experience of the single center	7
Unsuspected femoral hernias diagnosed during endoscopic inguinal hernia repair	7
The significance of the gut microbiome in children with functional constipation	7
Vedolizumab in highly resistant acute gastrointestinal graft-versus-host disease after allogeneic stem cell transplantation: A single-center pediatric series	7
CREB-associated glycosylation and function in human disease	7
Impact of diabetes on clinical and safety outcomes in acute ischemic stroke patients receiving reperfusion therapy: A meta-analysis	7
A meta-analysis on the role of brain-derived neurotrophic factor in Parkinson’s disease patients	7
Schaftoside improves cerebral ischemia-reperfusion injury by enhancing autophagy and reducing apoptosis and inflammation through the AMPK/mTOR pathway	7
SGLT2 inhibitors in non-diabetic kidney disease	7
LncRNA FEZF1-AS1 promotes colorectal cancer progression through regulating the miR-363-3p/PRRX1 pathway	7
The efficacy and safety of St. John’s wort extract in depression therapy compared to SSRIs in adults: A meta-analysis of randomized clinical trials	7
MicroRNA-125b overexpression in pseudoexfoliation syndrome	7
The emerging role of mood disorders in inflammatory bowel diseases	7
In vitro SEM analysis of desensitizing agents and experimental hydroxyapatite-based composition effectiveness in occluding dentin tubules	7
Characteristics of idiopathic inflammatory myopathies with novel myositis-specific autoantibodies	7
GP6 promotes the development of cerebral ischemic stroke induced by atherosclerosis via the FYN-PKA-pPTK2/FAK1 signaling pathway	7
Knockdown of miR-15b partially reverses the cisplatin resistance of NSCLC through the GSK-3β/MCL-1 pathway	7
Translational biomedicine-oriented exploratory research on bioactive rotifer-specific biopolymers	7
Trimethylamine N-oxide in cardiovascular disease	6
Knockdown of circular RNA hsa_circ_0003307 inhibits synovial inflammation in ankylosing spondylitis by regulating the PI3K/AKT pathway	6
Effects of amantadine and topiramate on neuronal damage in rats with experimental cerebral ischemia-reperfusion	6
Donanemab: Not two without a third	6
The effects of taxifolin on neuropathy related with hyperglycemia and neuropathic pain in rats: A biochemical and histopathological evaluation	6
MicroRNA-221 inhibits the transition of endothelial progenitor cells to mesenchymal cells via the PTEN/FoxO3a signaling pathway	6
Is home-based therapy in Fabry disease the answer to compelling patients’ needs during the COVID-19 pandemic? Survey results from the Polish FD Collaborative Group	6
Treatment results and safety assessment of the LARS system for the reconstruction of the anterior cruciate ligament	6
Impact of moderately reduced renal function on the diagnostic and prognostic value of galectin-3 in patients with exertional dyspnea	6
Quantitative shear wave elastography compared to standard ultrasound (qualitative B-mode grayscale sonography and quantitative power Doppler) for evaluation of achillotendinopathy in treatment-naïve i	6
Cerebral oxygenation and circulatory parameters during pressure-controlled vs volume-targeted mechanical ventilation in extremely preterm infants	6
Bibliometric analysis of acute respiratory distress syndrome (ARDS) studies published between 1980 and 2020	6
Silencing of lncRNA SNHG12 inhibits proliferation and migration of vascular smooth muscle cells via targeting miR-766-5p/EIF5A axis	6
Incidence and survival of ocular melanoma in National Cancer Registry of Poland in 2010–2017	6
The relationship between non-alcoholic fatty liver disease and incidence of chronic kidney disease for diabetic and non-diabetic subjects: A meta-analysis	6
Rare causes of anemia in liver diseases	6
High irisin and low BDNF levels in aqueous humor of high myopia	6
Impacts of COVID-19 lockdowns on frailty and wellbeing in older people and those living with long-term conditions	6
CircHIPK3 promotes bone microvascular endothelial cell proliferation, migration and angiogenesis by targeting miR-7 and KLF4/VEGF signaling in steroid-induced osteonecrosis of the femoral head	6
Neutrophil to lymphocyte ratio as noninvasive predictor of pulmonary vascular resistance increase in congestive heart failure patients: Single-center preliminary report	6
Dentists can provide reliable shear wave elastography measurements of the stiffness of masseter muscles: A possible scenario for a faster diagnostic process	6
Impact of COVID-19 on pancreatic cancer surgery: A high-volume Polish center experience	5
Assessment of dietary habits and lifestyle among people with HIV	5
Machine learning model-based risk prediction of severe complications after off-pump coronary artery bypass grafting	5
Hsa-circ-0000098 promotes the progression of hepatocellular carcinoma by regulation of miR-136-5p/MMP2 axis	5
Ocular complaints from students during COVID-19 pandemic	5
The true nature of P wave dispersion	5
The incidence of acute kidney injury in children undergoing allogenic hematopoietic stem cell transplantation: A pilot study	5
miRNA-323a-3p promoted intracranial, aneurysm-induced inflammation via AMPK/NF-κB signaling pathway by AdipoR1	5
Effects of position on non-stress test results and maternal satisfaction	5
Possibility of paclitaxel to induce the stemness-related characteristics of prostate cancer cells	5
Clinical implications of a diagnosis of taurodontism: A literature review	5
MicroRNA-197 promotes proliferation and inhibits apoptosis of gallbladder cancer cells by targeting insulin-like growth factor-binding protein 3	5
New methods of differentiation between primary and secondary hypertension in a pediatric population: A single-center experience	5
Dexamethasone promotes osteoblast apoptosis through the Chk2/p53 signaling pathway	5
Alzheimer’s trials: A cul-de-sac with no end in sight	5
MiR-let-7i inhibits CD4+ T cell apoptosis in patients with acute coronary syndrome	5
Pack-year cigarette smoking affects the course of palmoplantar pustulosis	5
Effects of ferroptosis in myocardial ischemia/reperfusion model of rat and its association with Sestrin 1	5
Hydrogen suppresses oxidative stress by inhibiting the p38 MAPK signaling pathway in preeclampsia	5
The impact of environmental air pollution on the prevalence of molar incisor hypomineralization in schoolchildren: A cross-sectional study	5
Reduction of hospital readmissions	5
Upregulation of centromere protein K is crucial for lung adenocarcinoma cell viability and invasion	5
Role of resistin in cardiovascular diseases: Implications for prevention and treatment	5
Eotaxin-2 as a potential marker of preterm premature rupture of membranes: A prospective, cohort, multicenter study	5
Adaptation of endovascular technique of self-expandable metal esophageal stent implantation in palliative treatment of malignant dysphagia in the course of esophageal and bronchial cancers: A one-cent	5
Metformin protects against abdominal aortic aneurysm by Atg7-induced autophagy	5
Transient spontaneous osteonecrosis of the knee (SONK) shortly after SARS-CoV-2 infection: A report of 2 cases	5
Influence of frailty syndrome on patient prognosis after coronary artery bypass grafting	5
Thyroid nodule ultrasound accuracy in predicting thyroid malignancy based on TIRADS system	5
Clinical assessment and comparison of ACL reconstruction using synthetic graft (Neoligaments versus FiberTape)	5
P wave duration in paroxysmal and persistent atrial fibrillation	5
The effect of serum uric acid levels on the long-term prognosis of patients with non-ST-elevation myocardial infarction	5
Differential expression of miRNAs from extracellular vesicles in chronic graft-versus-host disease: A preliminary study	5
MicroRNA-139-5p negatively regulates NME1 expression in hepatocellular carcinoma cells	5
Influence of formalized Predialysis Education Program (fPEP) on the chosen and definitive renal replacement therapy option	5
Molecular features as promising biomarkers in ovarian cancer	5
Helicobacter pylori infection is associated with increased accumulation of advanced glycation end products in the skin in patients with type 1 diabetes: A preliminary study	4
The functional and radiographic outcomes following distal radius fracture treatment in a cast for 4 and 6 weeks in the elderly: A randomized trial	4
The effects of adalimumab on the rat autotransplantation endometriosis model: A placebo-controlled randomized study	4
Cofilin-1 and profilin-1 expression in lung microvascular endothelial cells exposed to titanium dioxide nanoparticles	4

Effects of efavirenz and tenofovir on bone tissue in Wistar rats	4
Does PET scan have any role in the diagnosis of perineural spread associated with the head and neck tumors?	4
Determination of serum vascular endothelial growth factor (VEGF) and VEGF receptor levels with VEGF gene polymorphisms in patients with Behçet’s uveitis	4
Efficacy of different intensity of aquatic exercise in enhancing remyelination and neuronal plasticity using cuprizone model in male Wistar rats	4
Liver paraoxonase 3 expression and the effect of liraglutide treatment in a rat model of diabetes	4
Effects of ketamine, thiopental and their combination on the rat liver: A biochemical evaluation	4
Prevalence of CYLD mutations in Vietnamese patients with polycythemia vera	4
Risk factors and outcomes for acute respiratory failure in coronavirus disease 2019: An observational cohort study	4
P2Y12 inhibition in macrophages reduces ventricular arrhythmias in rats after myocardial ischemia-reperfusion	4
Dandelion root extracts abolish MAPK pathways to ameliorate experimental mouse ulcerative colitis	4
Preoperative and postoperative diagnostic efficiency of multi-inflammatory index on pain scoring of degenerated intervertebral disc	4
miRNA profiling of human nasopharyngeal carcinoma cell lines HONE1 and CNE2 after X-ray therapy	4
Application and efficacy of transcutaneous electrical acupoint stimulation (TEAS) in clinical practice: A systematic review	4
Analysis and comparison of autologous platelet-rich plasma preparation systems used in the treatment of enthesopathies: A preliminary study	4
Overexpression of HTRA1 increases the proliferation and migration of retinal pigment epithelium	4
Alpha-solanine inhibits endothelial inflammation via nuclear factor kappa B signaling pathway	4
The natural origins of cytostatic compounds used in rhabdomyosarcoma therapy	4
(−)-Epigallocatechin-3-gallate plays an antagonistic role in the antitumor effect of bortezomib in myeloma cells via activating Wnt/β-catenin signaling pathway	4
Extracellular Nampt (eNampt/Visfatin/PBEF) directly and indirectly stimulates ACTH and CCL2 protein secretion from isolated rat corticotropes	4
RPS27 selectively regulates the expression and alternative splicing of inflammatory and immune response genes in thyroid cancer cells	4
Updates for the diagnosis and management of cardiac amyloidosis	4
Gene network analysis of the transcriptome impact of methylated microRNAs on oral squamous cell carcinoma	4
Degenerative disease of the spine: How to relate clinical symptoms to radiological findings	4
Synthesis and characterization of atherosclerotic target anti-CD47 functionalized by nano- polyelectrolyte complexes between chitosan and hyaluronic acid and in vivo and in vitro targeting experiments	4
Severe cases of osteogenesis imperfecta type VIII due to a homozygous mutation in P3H1 (LEPRE1) and review of the literature	4
Arsenic trioxide induces the differentiation of retinoic acid-resistant neuroblastoma cells via upregulation of HoxC9	4
Standardization of the ultrasound examination of the masseter muscle with size-independent calculation of records	4
Bone tissue 3D bioprinting in regenerative dentistry through the perspective of the diamond concept of healing: A narrative review	4
Platelet sTWEAK and plasma IL-6 are associated with 18F-fluorodeoxyglucose uptake in right ventricles of patients with pulmonary arterial hypertension: A pilot study	4
Comparison of biomarker expression in oral lichen planus and oral lichenoid lesions	4