Advances in Clinical and Experimental Medicine

Article	Citations
Cerebral small vessel disease: A review	67
Monitoring the kynurenine system: Concentrations, ratios or what else?	47
Neurobiological advances of learned fear in humans	40
Comparison of the clinical differences between COVID-19, SARS, influenza, and the common cold: A systematic literature review	29
Aging, depression and dementia: The inflammatory process	25
Advances in ultrasound-guided thermal ablation for symptomatic benign thyroid nodules	24
Diagnosis of type 1 diabetes during the SARS-CoV-2 pandemic: Does lockdown affect the incidence and clinical status of patients?	24
Clinical value of soluble ST2 in cardiology	24
Recent advances in the study of the comorbidity of depressive and anxiety disorders	22
Preclinical modeling in depression and anxiety: Current challenges and future research directions	20
Expression and function of lncRNA MALAT1 in gestational diabetes mellitus	19
Continuous exposure of PM2.5 exacerbates ovalbumin-induced asthma in mouse lung via a JAK-STAT6 signaling pathway	19
Methods for assessing the severity of perinatal asphyxia and early prognostic tools in neonates with hypoxic–ischemic encephalopathy treated with therapeutic hypothermia	19
Advances in EEG-based functional connectivity approaches to the study of the central nervous system in health and disease	19
Clinical outcomes of continuous vs intermittent meropenem infusion for the treatment of sepsis: A systematic review and meta-analysis	19
Social participation of patients with multiple sclerosis	19
Hematological manifestations and complications of COVID-19	19
Oral cancer: The first symptoms and reasons for delaying correct diagnosis and appropriate treatment	18
Applications for graphene and its derivatives in medical devices: Current knowledge and future applications	18
Whole blood ACTB, B2M and GAPDH expression reflects activity of inflammatory bowel disease, advancement of colorectal cancer, and correlates with circulating inflammatory and angiogenic factors: Relev	17
Acute kidney injury in patients with COVID-19: Epidemiology, pathogenesis and treatment	17
Arbutin inhibits inflammation and apoptosis by enhancing autophagy via SIRT1	16
Baicalein modulates the radiosensitivity of cervical cancer cells in vitro via miR-183 and the JAK2/STAT3 signaling pathway	15
Paclitaxel inhibits proliferation and invasion and promotes apoptosis of breast cancer cells by blocking activation of the PI3K/AKT signaling pathway	15
Lethal and life-limiting skeletal dysplasias: Selected prenatal issues	15

Additive manufacturing technologies enabling rapid and interventional production of protective face shields and masks during the COVID-19 pandemic	14
IgA vasculitis with nephritis in children	14
Puerarin pretreatment inhibits myocardial apoptosis and improves cardiac function in rats after acute myocardial infarction through the PI3K/Akt signaling pathway	14
Machine learning in orthodontics: Challenges and perspectives	14
Intestinal amyloidosis: Clinical manifestations and diagnostic challenge	13
In vivo delivery of MMP3-shRNA and Sox9 lentivirus cocktail enhances matrix synthesis to prevent lumbar disc degeneration	13
Effects of miR-124-3p regulation of the p38MAPK signaling pathway via MEKK3 on apoptosis and proliferation of macrophages in mice with coronary atherosclerosis	13
Stilbene glycoside upregulates SIRT3/AMPK to promotes neuronal mitochondrial autophagy and inhibit apoptosis in ischemic stroke	13
Interleukin 6: biological significance and role in inflammatory bowel diseases	13
MiR-124 protects against cognitive dysfunction induced by sevoflurane anesthesia in vivo and in vitro through targeting calpain small subunit 1 via NF-κB signaling pathway	13
miR-21-5p protects hippocampal neurons of epileptic rats via inhibiting STAT3 expression	12
Exosome EpCAM promotes the metastasis of glioma by targeting the CD44 signaling molecule on the surface of glioma cells	12
Crocin attenuates oxidative and inflammatory stress-related periodontitis in cardiac tissues in rats	12
Pharmacokinetics of xanthohumol in rats of both sexes after oral and intravenous administration of pure xanthohumol and prenylflavonoid extract	12
Association between the long-term exposure to air pollution and depression	12
Pruritus in renal transplant recipients: Current state of knowledge	12
Echinatin mitigates H2O2-induced oxidative damage and apoptosis in lens epithelial cells via the Nrf2/HO-1 pathway	12
LncRNA PCGEM1 mediates oxaliplatin resistance in hepatocellular carcinoma via miR-129-5p/ETV1 axis in vitro	12
LncRNA ANRIL negatively regulated chitooligosaccharide-induced radiosensitivity in colon cancer cells by sponging miR-181a-5p	11
Inflammation and diet: Focus on mental and cognitive health	11
Face masks use during the COVID-19 pandemic: Differences in attitudes and practices between medical and non-medical students. A survey of 2256 students in Poland	11
Anti-cancer effect of engineered recombinant interleukin 18	11
Investigation of the role of miR-221 in diabetic peripheral neuropathy and related molecular mechanisms	10
The clinical value of high-density lipoprotein in the evaluation of new coronavirus pneumonia	10
Ganoderic acid A inhibits ox-LDL-induced THP-1-derived macrophage inflammation and lipid deposition via Notch1/PPARγ/CD36 signaling	10
CircHIPK3 promotes neuroinflammation through regulation of the miR-124-3p/STAT3/NLRP3 signaling pathway in Parkinson’s disease	10
The role of GLP-1/GIP receptor agonists in Alzheimer’s disease	10
Laser dentistry in daily practice during the COVID-19 pandemic: Benefits, risks and recommendations for safe treatments	10
Risk factors of recurrence and poor survival in curatively resected hepatocellular carcinoma with microvascular invasion	10
Evaluation of Er:YAG and Er,Cr:YSGG laser irradiation for the debonding of prefabricated zirconia crowns	10
LncRNA NORAD regulates scar hypertrophy via miRNA-26a mediating the regulation of TGFβR1/2	9
EGCG decreases myocardial infarction in both I/R and MIRI rats through reducing intracellular Ca2+ and increasing TnT levels in cardiomyocytes	9
miR-874 ameliorates retinopathy in diabetic rats by NF-κB signaling pathway	9
CD147 promotes invasion and MMP-9 expression through MEK signaling and predicts poor prognosis in hypopharyngeal squamous cell carcinoma	9
Lecanemab (Leqembi) is not the right drug for patients with Alzheimer’s disease	9
miR-124-3p targeting of TGF-β1 inhibits the proliferation of hypertrophic scar fibroblasts	9
Effectiveness of TI-RADS and ATA classifications for predicting malignancy of thyroid nodules	9
Melatonin protected against myocardial infarction injury in rats through a Sirt6-dependent antioxidant pathway	9
Ultrafiltration in acute heart failure: Current knowledge and fields for further research	9
Soluble syndecan-1 as marker of intestinal inflammation: A preliminary study and evaluation of a new panel of biomarkers for non-invasive prediction of active ulcerative colitis	8
Gender differences in variables associated with dipeptidyl peptidase 4 genetic polymorphisms in coronary artery disease	8
Dualistic role of autophagy in cancer progression	8
Cornelian cherry extract ameliorates osteoporosis associated with hypercholesterolemia in New Zealand rabbits	8
Influence of SARS-CoV-2 infection on thyroid gland function: The current knowledge	8
Comparative biomechanical testing of customized three-dimensional printing acetabular-wing plates for complex acetabular fractures	8
Therapeutic role of vanillin receptors in cancer	8
Effect of adenosine triphosphate, benidipine and their combinations on bevacizumab-induced kidney damage in rats	8
Cancer patients and internal medicine patients attitude towards COVID-19 vaccination in Poland	8
Classification algorithm of patients with endometriosis: Proposal for tailored management	8
Is serum anti-Müllerian hormone (AMH) assay a satisfactory measure for ovarian reserve estimation? A comparison of serum and peritoneal fluid AMH levels	8

The relation of endocan and galectin-3 with ST-segment resolution in patients with ST-segment elevation myocardial infarction	8
Wharton’s jelly-derived mesenchymal stem cells in the treatment of four patients with alopecia areata	8
USP26 deubiquitinates androgen receptor (AR) in the maintenance of sperm maturation and spermatogenesis through the androgen receptor signaling pathway	8
Overexpression of GSTP1 promotes colorectal cancer cell proliferation, invasion and metastasis by upregulating STAT3	8
Infectious diseases of the skin in contact sports	8
Three cases of 3β-hydroxysteroid dehydrogenase deficiency: Clinical analysis	7
Oxidative and pro-inflammatory lung injury induced by desflurane inhalation in rats and the protective effect of rutin	7
Unsuspected femoral hernias diagnosed during endoscopic inguinal hernia repair	7
In vitro SEM analysis of desensitizing agents and experimental hydroxyapatite-based composition effectiveness in occluding dentin tubules	7
Prediction of prognosis in sepsis patients by the SOFA score combined with miR-150	7
Expressions of miR-122a and miR-3195 in laryngeal cancer and their effects on the proliferation and apoptosis of laryngeal cancer cell Hep-2	7
The emerging role of mood disorders in inflammatory bowel diseases	7
The effect of diabetes on vitreous levels of adiponectin and inflammatory cytokines in experimental rat model	7
Ketamine alleviates HMGB1-induced acute lung injury through TLR4 signaling pathway	7
Evaluation of the relationship between splenic iron overload and liver, heart and muscle features evident on T2*-weighted magnetic resonance imaging	7
The significance of angiotensin II type 1 receptor (AT1 receptor) in renal transplant injury	7
The role of genetic factors in carpal tunnel syndrome etiology: A review	7
Is home-based therapy in Fabry disease the answer to compelling patients’ needs during the COVID-19 pandemic? Survey results from the Polish FD Collaborative Group	7
The effect of taxifolin on high-dose-cisplatin-induced oxidative liver injury in rats	7
Effect of thiamine pyrophosphate on cyclophosphamide-induced oxidative ovarian damage and reproductive dysfunction in female rats	7
Effects of calcium electroporation, electrochemotherapy, and irreversible electroporation on quality of life and progression-free survival in patients with pancreatic cancer: IREC clinical study	7
Extracorporeal shockwave therapy enhances peripheral nerve remyelination and gait function in a crush model	7
GLP-1 receptor agonists, polycystic ovary syndrome and reproductive dysfunction: Current research and future horizons	7
lncRNA PSMA3-AS1 promotes the progression of non-small cell lung cancer through targeting miR-17-5p/PD-L1	7
Anticoagulant-related nephropathy: Focus on novel agents. A review	7
Effect of matrine on JAK2/STAT3 signaling pathway and brain protection in rats with cerebral ischemia-reperfusion	7
Impaired fertility in women and men with chronic kidney disease	6
Characteristics of idiopathic inflammatory myopathies with novel myositis-specific autoantibodies	6
MicroRNA-125b overexpression in pseudoexfoliation syndrome	6
MYBL2 in synergy with CDC20 promotes the proliferation and inhibits apoptosis of gastric cancer cells	6
Meta-analysis of the diagnostic value of procalcitonin in adult burn sepsis	6
SGLT2 inhibitors in non-diabetic kidney disease	6
GP6 promotes the development of cerebral ischemic stroke induced by atherosclerosis via the FYN-PKA-pPTK2/FAK1 signaling pathway	6
Predictive factors in post-stroke epilepsy: Retrospective analysis	6
The small heterodimer partner inhibits activation of hepatic stellate cells via autophagy	6
Ketamine alleviates HMGB1-induced acute lung injury through TLR4 signaling pathway	6
Translational biomedicine-oriented exploratory research on bioactive rotifer-specific biopolymers	6
Secondary skin neoplasms in patients after autologous and allogeneic hematopoietic stem cell transplantation procedures	6
Relationships between circulating galectin-3, extracellular matrix fibrosis and outcomes in dilated cardiomyopathy	6
A prognostic signature based on the expression profile of the ferroptosis-related long non-coding RNAs in hepatocellular carcinoma	6
Evaluation of the association between angiotensin converting enzyme insertion/deletion polymorphism and the risk of endometrial cancer in and characteristics of Polish women	6
Single vs dual rod constructs in early onset scoliosis treated with magnetically controlled growing rods	6
The impact of health education on treatment outcomes in heart failure patients	6
Introducing enhanced recovery after surgery protocol in pediatric surgery	6
Comparison of a manual walking platform and the CatWalk gait analysis system in a rat osteoarthritis model	6
Impacts of COVID-19 lockdowns on frailty and wellbeing in older people and those living with long-term conditions	6
MicroRNA-221 inhibits the transition of endothelial progenitor cells to mesenchymal cells via the PTEN/FoxO3a signaling pathway	6
The three-point bending test of fiber-reinforced composite root canal posts	6
Dentists can provide reliable shear wave elastography measurements of the stiffness of masseter muscles: A possible scenario for a faster diagnostic process	6
Organ of hearing and balance in peri- and postmenopausal women. Effects of hormone replacement therapy on hearing and balance in peri- and post-menopausal women: The current state of knowledge	5
Ocular complaints from students during COVID-19 pandemic	5
Schaftoside improves cerebral ischemia-reperfusion injury by enhancing autophagy and reducing apoptosis and inflammation through the AMPK/mTOR pathway	5
Enzyme activity and genetic polymorphisms in patients with type II diabetes mellitus	5
LncRNA FEZF1-AS1 promotes colorectal cancer progression through regulating the miR-363-3p/PRRX1 pathway	5
P wave duration in paroxysmal and persistent atrial fibrillation	5
The effectiveness of methotrexate and low-dose steroid therapy in the treatment of idiopathic granulomatous mastitis	5
High irisin and low BDNF levels in aqueous humor of high myopia	5
Weighted gene co-expression network analysis to investigate the key genes implicated in global brain ischemia/reperfusion injury in rats	5
Association of gene polymorphisms of KLK3 and prostate cancer: A meta-analysis	5
Incidence and survival of ocular melanoma in National Cancer Registry of Poland in 2010–2017	5
Non-secretory multiple myeloma: Diagnosis and management	5
Dihydroartemisinin/miR-29b combination therapy increases the pro-apoptotic effect of dihydroartemisinin on cholangiocarcinoma cell lines by regulating Mcl-1 expression	5
The effects of miR-140-5p on the biological characteristics of ovarian cancer cells through the Wnt signaling pathway	5
CREB-associated glycosylation and function in human disease	5
The incidence of acute kidney injury in children undergoing allogenic hematopoietic stem cell transplantation: A pilot study	5
The efficacy and safety of St. John’s wort extract in depression therapy compared to SSRIs in adults: A meta-analysis of randomized clinical trials	5
Trimethylamine N-oxide in cardiovascular disease	5
Large animals as models of atrial fibrillation	5
Pharmacotherapeutic pain management in patients undergoing laparoscopic cholecystectomy: A review	5
miRNA-323a-3p promoted intracranial, aneurysm-induced inflammation via AMPK/NF-κB signaling pathway by AdipoR1	5
Adalimumab in the treatment of non-infectious uveitis	5
The significance of the gut microbiome in children with functional constipation	5
Knockdown of circular RNA hsa_circ_0003307 inhibits synovial inflammation in ankylosing spondylitis by regulating the PI3K/AKT pathway	5
MicroRNA-197 promotes proliferation and inhibits apoptosis of gallbladder cancer cells by targeting insulin-like growth factor-binding protein 3	5
Role of resistin in cardiovascular diseases: Implications for prevention and treatment	5
Metformin protects against abdominal aortic aneurysm by Atg7-induced autophagy	5
Phenotyping in heart failure with preserved ejection fraction: A key to find effective treatment	5
Dexamethasone promotes osteoblast apoptosis through the Chk2/p53 signaling pathway	5
Effects of ferroptosis in myocardial ischemia/reperfusion model of rat and its association with Sestrin 1	5
Vedolizumab in highly resistant acute gastrointestinal graft-versus-host disease after allogeneic stem cell transplantation: A single-center pediatric series	5

Influence of frailty syndrome on patient prognosis after coronary artery bypass grafting	5
The true nature of P wave dispersion	5
Diffusion tensor imaging of normal-appearing cervical spinal cords in patients with multiple sclerosis: Correlations with clinical evaluation and cerebral diffusion tensor imaging changes. Preliminary	5
Recent advances in the study of the neurobiological mechanisms behind the effects of physical activity on mood, resilience and emotional disorders	5
Basal cell carcinoma secondary to trauma: A 3-year experience of the single center	5
Rare causes of anemia in liver diseases	5
The impact of environmental air pollution on the prevalence of molar incisor hypomineralization in schoolchildren: A cross-sectional study	5
The effect of serum uric acid levels on the long-term prognosis of patients with non-ST-elevation myocardial infarction	5
Skin conductance measurement for the assessment of analgosedation adequacy in infants treated with mechanical ventilation: A multicenter pilot study	5
Relationship between serum potassium level and survival outcome in out-of-hospital cardiac arrest using CAPTURES database of Korea: Does hypokalemia have good neurological outcomes in out-of-hospital	5
Silencing of lncRNA SNHG12 inhibits proliferation and migration of vascular smooth muscle cells via targeting miR-766-5p/EIF5A axis	5
Clinical assessment and comparison of ACL reconstruction using synthetic graft (Neoligaments versus FiberTape)	5
Alzheimer’s trials: A cul-de-sac with no end in sight	5
MicroRNA-24 inhibits CDX1 expression in decidual tissues of recurrent spontaneous abortion mice to reduce the abortion risk	5
The preservation effect of coronary collateral circulation on left ventricular function in chronic total occlusion and its association with the expression of vascular endothelial growth factor A	4
Upregulation of centromere protein K is crucial for lung adenocarcinoma cell viability and invasion	4
Eotaxin-2 as a potential marker of preterm premature rupture of membranes: A prospective, cohort, multicenter study	4
Gene network analysis of the transcriptome impact of methylated microRNAs on oral squamous cell carcinoma	4
The functional and radiographic outcomes following distal radius fracture treatment in a cast for 4 and 6 weeks in the elderly: A randomized trial	4
Anticancer activity of topical ointments with histone deacetylase inhibitor, trichostatin A	4
Analysis and comparison of autologous platelet-rich plasma preparation systems used in the treatment of enthesopathies: A preliminary study	4
Risk factors and outcomes for acute respiratory failure in coronavirus disease 2019: An observational cohort study	4
Efficacy of different intensity of aquatic exercise in enhancing remyelination and neuronal plasticity using cuprizone model in male Wistar rats	4
Efficacy of intra-arterial lidocaine infusion in the treatment of cerulein-induced acute pancreatitis	4
Influence of formalized Predialysis Education Program (fPEP) on the chosen and definitive renal replacement therapy option	4
Platelet sTWEAK and plasma IL-6 are associated with 18F-fluorodeoxyglucose uptake in right ventricles of patients with pulmonary arterial hypertension: A pilot study	4
Reduction of hospital readmissions	4
Cerebral tissue oxygenation during cranial osteopathic CV4 procedure in newborns	4
The relationship between non-alcoholic fatty liver disease and incidence of chronic kidney disease for diabetic and non-diabetic subjects: A meta-analysis	4
Treatment results and safety assessment of the LARS system for the reconstruction of the anterior cruciate ligament	4
Thermal effect of Er:YAG and Er,Cr:YSGG used for debonding ceramic and metal orthodontic brackets: An experimental analysis	4
Synthesis and characterization of atherosclerotic target anti-CD47 functionalized by nano- polyelectrolyte complexes between chitosan and hyaluronic acid and in vivo and in vitro targeting experiments	4
Severe cases of osteogenesis imperfecta type VIII due to a homozygous mutation in P3H1 (LEPRE1) and review of the literature	4
Knockdown of miR-15b partially reverses the cisplatin resistance of NSCLC through the GSK-3β/MCL-1 pathway	4
Antiviral treatment in congenital HCMV infection: The six-year experience of a single neonatal center in Poland	4
Effects of amantadine and topiramate on neuronal damage in rats with experimental cerebral ischemia-reperfusion	4
Possibility of paclitaxel to induce the stemness-related characteristics of prostate cancer cells	4
The protective effect of hypothermia on postoperative cognitive deficit may be attenuated by prolonged coronary artery bypass time: Meta-analysis and meta-regression	4
Impact of COVID-19 on pancreatic cancer surgery: A high-volume Polish center experience	4
Helicobacter pylori infection is associated with increased accumulation of advanced glycation end products in the skin in patients with type 1 diabetes: A preliminary study	4
Dandelion root extracts abolish MAPK pathways to ameliorate experimental mouse ulcerative colitis	4
New methods of differentiation between primary and secondary hypertension in a pediatric population: A single-center experience	4
Monocyte chemoattractant protein-1, macrophage colony stimulating factor, survivin, and tissue inhibitor of matrix metalloproteinases-2 in analysis of damage and repair related to pediatric chronic ki	4
Updates for the diagnosis and management of cardiac amyloidosis	4
Mayer–Rokitansky–Küster–Hauser syndrome as an interdisciplinary problem	4
Impact of diabetes on clinical and safety outcomes in acute ischemic stroke patients receiving reperfusion therapy: A meta-analysis	4
Platelet polyphosphate level is elevated in patients with chronic primary thrombocytopenia: A preliminary study	4
The assessment of phonatory and ventilatory functions in patients after microsurgery for Reinke’s edema	4
Single nucleotide polymorphisms of SCN5A and SCN10A genes increase the risk of ventricular arrhythmias during myocardial infarction	4