OOIR: Observatory of International Research

Papers

(The median citation count of Bioscience Trends is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The positive role of traditional Chinese medicine as an adjunctive therapy for cancer	146
Surgical treatment of hepatocellular carcinoma	85
Overview of the characteristics of and responses to the three waves of COVID-19 in Japan during 2020-2021	82
The clinical management of hepatocellular carcinoma worldwide: A concise review and comparison of current guidelines: 2022 update	79
Conversion therapy and maintenance therapy for primary hepatocellular carcinoma	72
Current state of care for the elderly in China in the context of an aging population	61
Changes in and challenges regarding the surgical treatment of hepatocellular carcinoma in China	51
COVID-19 vaccine research focusses on safety, efficacy, immunoinformatics, and vaccine production and delivery: a bibliometric analysis based on VOSviewer	46
Advances in the surgical treatment of liver cancer	44
Use of chemotherapy to treat hepatocellular carcinoma	41
New challenges to fighting COVID-19: Virus variants, potential vaccines, and development of antivirals	34
Revealing the magic of acupuncture based on biological mechanisms: A literature review	34
Update on hormone therapy for the management of postmenopausal women	26
Marburg virus disease: A deadly rare virus is coming	26
The strategy behind Japan's response to COVID-19 from 2020-2021 and future challenges posed by the uncertainty of the Omicron variant in 2022	23
The C-reactive protein to albumin ratio is an excellent prognostic predictor for gallbladder cancer	21
Traditional Chinese medicine for treatment of novel infectious diseases: Current status and dilemma	21
The role of Toll-like receptors in neurobiology of alcoholism	20
Hepatic stellate cell exosome-derived circWDR25 promotes the progression of hepatocellular carcinoma <i>via</i> the miRNA-4474-3P-ALOX-15 and EMT axes	19
The multidisciplinary management of hepatocellular carcinoma with portal vein tumor thrombus	18
Conversion therapy with an immune checkpoint inhibitor and an antiangiogenic drug for advanced hepatocellular carcinoma: A review	17
MCM4 in human hepatocellular carcinoma: a potent prognostic factor associated with cell proliferation	15
The E2F transcription factor 2: What do we know?	15
From SARS to the Omicron variant of COVID-19: China's policy adjustments and changes to prevent and control infectious diseases	15
Latest updates on COVID-19 vaccines	15

The management of dementia worldwide: A review on policy practices, clinical guidelines, end-of-life care, and challenge along with aging population	14
Treating patients infected with the SARS-CoV-2 Omicron variant with a traditional Chinese medicine, Shufeng Jiedu capsule	14
Increasing demand for point-of-care testing and the potential to incorporate the Internet of medical things in an integrated health management system	13
Rapid SARS-CoV-2 antigen detection potentiates early diagnosis of COVID-19 disease	12
Herbal medicines exhibit a high affinity for ACE2 in treating COVID-19	12
The impact of COVID-19 pandemic on the utilization of ambulatory care for patients with chronic neurological diseases in Japan: Evaluation of an administrative claims database	12
Depletion of circ-BIRC6, a circular RNA, suppresses non-small cell lung cancer progression by targeting miR-4491	12
Infectious disease activity during the COVID-19 epidemic in Japan: Lessons learned from prevention and control measures	11
Role of a multidisciplinary team (MDT) in the diagnosis, treatment, and outcomes of inflammatory bowel disease: a single Chinese center's experience	11
Formulation and interpretation of the Chinese Guidelines for Surgical Treatment of Obesity and Type 2 Diabetes Mellitus	11
The ability of Segmenting Anything Model (SAM) to segment ultrasound images	11
Vasa previa: Perinatal outcomes in singleton and multiple pregnancies	10
Elevated serum CA19-9 indicates severe liver inflammation and worse survival after curative resection in hepatitis B-related hepatocellular carcinoma	10
Bacteriophage therapy for empyema caused by carbapenem-resistant <i>Pseudomonas aeruginosa </i>	10
China should emphasize key issues inherent in rational medication management for the elderly	10
Combination of albumin-bilirubin grade and clinically significant portal hypertension predicts the prognosis of patients with hepatocellular carcinoma after liver resection	10
An overview: Management of patients with advanced hepatocellular carcinoma	10
Burnout in nurses during the COVID-19 pandemic in China: New challenges for public health	10
Transitional care during COVID-19 pandemic in Japan: Calls for new strategies to integrate traditional approaches with information and communication technologies	9
Trends in managing COVID-19 from an emerging infectious disease to a common respiratory infectious disease: What are the subsequent impacts on and new challenges for healthcare systems?	8
New possibilities for medical support systems utilizing artificial intelligence (AI) and data platforms	8
Impact of China's COVID-19 prevention and control efforts on outbreaks of influenza	8
Alzheimer's disease with frailty: Prevalence, screening, assessment, intervention strategies and challenges	8
An average of nearly 200,000 new infections per day over a six-week period: What is the impact of such a severe COVID-19 pandemic on the healthcare system in Japan?	8
Soluble β-amyloid impaired the GABA inhibition by mediating KCC2 in early APP/PS1 mice	8
Liver transplantation in China: Achievements over the past 30 years and prospects for the future	8
Opportunities and challenges to the use of neutralizing monoclonal antibody therapies for COVID-19	8
How do RNA binding proteins trigger liquid-liquid phase separation in human health and diseases?	8
Considerations and guidance to control the rebound in COVID-19 cases	7
What is always necessary throughout efforts to prevent and control COVID-19 and other infectious diseases? A physical containment strategy and public mobilization and management	7
Value of multidisciplinary team (MDT) in minimally invasive treatment of complex intrahepatic bile duct stones	7
For COVID-19, what are the priorities of normalized prevention and control strategies?	7
Factors affecting mode of delivery in women of advanced maternal age	7
Neoadjuvant therapy <i>vs</i>. upfront surgery for resectable pancreatic cancer: An update on a systematic review and meta-analysis	7
Current status of gastroesophageal reflux disease after sleeve gastrectomy: Still a long way to go	7
Association between sarcopenia with incident cardio-cerebrovascular disease: A systematic review and meta-analysis	7
What does oral care mean to society?	7
The potential of 'Segment Anything' (SAM) for universal intelligent ultrasound image guidance	6
Needs of cancer patients during the SARS-CoV-2 Omicron lockdown: A population-based survey in Shanghai, China	6
The prognostic nutritional index and tumor pathological characteristics predict the prognosis of elderly patients with early-stage hepatocellular carcinoma after surgery	6
Using a multidisciplinary team for the staged management and optimally minimally invasive treatment of severe acute pancreatitis	6
Metformin acts on the gut-brain axis to ameliorate antipsychotic-induced metabolic dysfunction	6
Trends in the treatment of pancreatic cancer in Japan	6
Immunity debt: Hospitals need to be prepared in advance for multiple respiratory diseases that tend to co-occur	6
Can kynurenine pathway be considered as a next-generation therapeutic target for Parkinson's disease? An update information	6
Liquid-liquid phase separation: A new perspective to understanding aging and pathogenesis	6
Epigenetic modification of <i>Kiss1</i> gene expression in the AVPV is essential for female reproductive aging	6
Cisatracurium attenuates LPS-induced modulation of MMP3 and junctional protein expression in human microvascular endothelial cells	6
More effective vaccines and oral antivirals: Keys for the battle against Omicron	6
Rapid evolution of the COVID-19 pandemic calls for a unified public health response	6

Monkeypox – A danger approaching Asia	5
Efficacy of early hydroxychloroquine treatment in preventing COVID-19 pneumonia aggravation, the experience from Shanghai, China	5
The effect of the female genital tract and gut microbiome on reproductive dysfunction	5
New progress in elucidating the relationship between cancer therapy and cardiovascular toxicity	5
Inclusive education of elementary students with autism spectrum disorders in Shanghai, China: From the teachers' perspective	5
Effect of dehydroepiandrosterone on atherosclerosis in postmenopausal women	5
Update: Drug treatment options for coronavirus disease 2019 (COVID-19)	5
Focusing on development of novel sampling approaches and alternative therapies for COVID-19: Are they still useful in an era after the pandemic?	5
The preventive effect of loganin on oxidative stress-induced cellular damage in human keratinocyte HaCaT cells	5
C-C chemokine receptor type 6 modulates the biological function of osteoblastogenesis by altering the expression levels of Osterix and OPG/RANKL	5
Sequelae of long COVID, known and unknown: A review of updated information	5
A comparative study of contrast-enhanced ultrasound and contrast-enhanced CT for the detection and characterization of renal masses	5
Facing frailty: Are you ready?	4
Trends in the surgical treatment for pancreatic cancer in the last 30 years	4
Detecting latent tuberculosis infection with a breath test using mass spectrometer: A pilot cross-sectional study	4
Current status of and challenges posed by autism spectrum disorders in China: Prevalence, legal issues, and public awareness	4
Prevention and treatment strategies for type 2 diabetes based on regulating intestinal flora	4
An expanded view of infertility: The challenge of the changing profiling of major birth defects in China	4
Clinical guidelines for the diagnosis and treatment of HIV/AIDS in China: Their potential benefits and impact on public health	4
Can nasal irrigation with chlorine dioxide be considered as a potential alternative therapy for respiratory infectious diseases? The example of COVID-19	4
Influence of intermittent fasting on autophagy in the liver	4
Healthy aging, early screening, and interventions for frailty in the elderly	4
Tetracycline plus macrolide: A potential therapeutic regimen for COVID-19?	4
Liver transplantation for patients with hepatocellular carcinoma: Its current status and advances	4
The role of influenza in the era of COVID-19: Can we forget it?	4
Emerging infectious diseases never end: The fight continues	3
A brief summary regarding the roles of interleukin-11 in neurological diseases	3
A circadian rhythm-restricted diet regulates autophagy to improve cognitive function and prolong lifespan	3
Advances in deep learning: From diagnosis to treatment	3
The immunological characteristics of gallbladder carcinoma and advances in immunotherapy practices	3
Surgical indications for solid hepatic benign tumors: An updated literature review	3
Genetic features of TP53 mutation and its downstream FOXA1 in prostate cancer	3
Community-acquired pneumonia: Trends in and research on drug resistance and advances in new antibiotics	3
Optimized concurrent hearing and genetic screening in Beijing, China: A cross-sectional study	3
Treatment of biliary tract carcinoma over the last 30 years	3
Role of key amino acids in the transmembrane domain of the Newcastle disease virus fusion protein	3
New mechanisms: From lactate to lactylation to rescue heart failure	3
The framework for modern community medicine in Japan	3
HIV/AIDS strategies should focus on outcomes and the psychological status of older patients diagnosed with HIV	3
Role of circulating tumor cell detection in differentiating tumor recurrence from treatment necrosis of brain gliomas	3
The status of surrogacy in China	3
A well-matched marriage of immunotherapy and radiofrequency ablation to reduce the relapse and progression of hepatocellular carcinoma	3
Effects and mechanisms of microenvironmental acidosis on osteoclast biology	3
FOXA2 plays a critical role in hepatocellular carcinoma progression and lenvatinib-associated drug resistance	3
Sarcopenia and risk of cardio-cerebrovascular disease: A two-sample Mendelian randomization study	3
Current status and perspectives of non-coding RNA and phase separation interactions	3
Neoadjuvant therapies in resectable hepatocellular carcinoma: Exploring strategies to improve prognosis	2
Different clinical guidelines, common goal: To reduce COVID-19 mortality	2
Donor-recipient matching in adult liver transplantation: Current status and advances	2
Contemporary oral anticoagulant therapy of patients with atrial fibrillation in China: Status, obstacles, and strategies for improvement	2
Notch signaling pathway plays a critical role in chemotherapeutic drug-induced vestibular injury	2
Characteristics, scope of activity, and negative emotions in elderly women with urinary incontinence: Based on a longitudinal follow-up in Shanghai, China	2
Elderly patients with comorbid hypertension who prefer primary care have a lower rate of polypharmacy: A cross-sectional study in Shanghai, China	2
Interaction with ERp57 is required for progranulin protection against Type 2 Gaucher disease	2
Predictive deep learning models for cognitive risk using accessible data	2
Association of HIV infection with metabolic syndrome among normal or underweight young adults: evidence from the CHART cohort	2
The application and prospection of augmented reality in hepato-pancreato-biliary surgery	2
Comparison of diagnosis-related groups (DRG)-based hospital payment system design and implementation strategies in different countries: The case of ischemic stroke	2
Timing of parathyroidectomy for kidney transplant patients with secondary hyperparathyroidism: A practical overview	2
How should designated COVID-19 hospitals in megacities implement a precise management strategy in response to Omicron?	2
Conversion therapy for initially unresectable hepatocellular carcinoma: Current status and prospects	2
Impact of sarcopenia on S1 adjuvant chemotherapy and prognosis in pancreatic cancer patients	2
Association between abnormal lipid metabolism and Alzheimer's disease: New research has revealed significant findings on the APOE4 genotype in microglia	2
Replication Factor C4 in human hepatocellular carcinoma: A potent prognostic factor associated with cell proliferation	2
Reflections on abortion rights: From policy to medicine	2
Verification of the efficiency of saline gargle sampling for detection of the Omicron variant of SARS-CoV-2, a pilot study	2
Pal power: Demonstration of the functional association of the <i>Helicobacter pylori</i> flagellar motor with peptidoglycan-associated lipoprotein (Pal) and its preliminary crystallographi	2
Impact of patient age on outcome after resection for hepatocellular carcinoma	2
Association of angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists use with risk of atrial fibrillation after pacemaker implantation among very old patients	2
Revealing the gut microbiome mystery: A meta-analysis revealing differences between individuals with autism spectrum disorder and neurotypical children	2
Association of MTHFR 677C>T polymorphism with pregnancy outcomes in IVF/ICSI-ET recipients with adequate synthetic folic acid supplementation	2
An innovative two-wing model for balancing the demands of inpatients with COVID-19 and general medical service in a designated hospital for COVID-19 in Shenzhen, China	2
Devising novel near-infrared aggregation-induced-emission luminogen labeling for point-of-care diagnosis of <i>Mycobacterium tuberculosis </i>	2
A predictive radiotranscriptomics model based on DCE-MRI for tumor immune landscape and immunotherapy in cholangiocarcinoma	2