OOIR: Observatory of International Research

Papers

(The median citation count of Bioscience Trends is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-07-01 to 2024-07-01.)

Article	Citations
The positive role of traditional Chinese medicine as an adjunctive therapy for cancer	121
Overview of the characteristics of and responses to the three waves of COVID-19 in Japan during 2020-2021	77
Surgical treatment of hepatocellular carcinoma	77
Analysis of coagulation parameters in patients with COVID-19 in Shanghai, China	73
The clinical management of hepatocellular carcinoma worldwide: A concise review and comparison of current guidelines: 2022 update	66
Conversion therapy and maintenance therapy for primary hepatocellular carcinoma	59
Current state of care for the elderly in China in the context of an aging population	51
COVID-19 vaccine research focusses on safety, efficacy, immunoinformatics, and vaccine production and delivery: a bibliometric analysis based on VOSviewer	44
Changes in and challenges regarding the surgical treatment of hepatocellular carcinoma in China	44
Use of chemotherapy to treat hepatocellular carcinoma	37
New challenges to fighting COVID-19: Virus variants, potential vaccines, and development of antivirals	33
Advances in the surgical treatment of liver cancer	32
Revealing the magic of acupuncture based on biological mechanisms: A literature review	31
Systemic treatment of advanced or recurrent biliary tract cancer	30
CAR-expressing NK cells for cancer therapy: a new hope	25
Marburg virus disease: A deadly rare virus is coming	24
Exploration and correlation analysis of changes in Krebs von den Lungen-6 levels in COVID-19 patients with different types in China	23
Update on hormone therapy for the management of postmenopausal women	23
The strategy behind Japan's response to COVID-19 from 2020-2021 and future challenges posed by the uncertainty of the Omicron variant in 2022	21
Traditional Chinese medicine for treatment of novel infectious diseases: Current status and dilemma	20
Hepatic stellate cell exosome-derived circWDR25 promotes the progression of hepatocellular carcinoma <i>via</i> the miRNA-4474-3P-ALOX-15 and EMT axes	19
Realizing 5G- and AI-based doctor-to-doctor remote diagnosis: opportunities, challenges, and prospects	19
The role of Toll-like receptors in neurobiology of alcoholism	19
The C-reactive protein to albumin ratio is an excellent prognostic predictor for gallbladder cancer	18
Safety and feasibility of laparoscopic versus open liver resection with associated lymphadenectomy for intrahepatic cholangiocarcinoma	16

The multidisciplinary management of hepatocellular carcinoma with portal vein tumor thrombus	16
Conversion therapy with an immune checkpoint inhibitor and an antiangiogenic drug for advanced hepatocellular carcinoma: A review	16
An international comparison analysis of reserve and supply system for emergency medical supplies between China, the United States, Australia, and Canada	16
Latest updates on COVID-19 vaccines	15
MCM4 in human hepatocellular carcinoma: a potent prognostic factor associated with cell proliferation	15
Promoting social engagement of the elderly to cope with aging of the Chinese population	15
From SARS to the Omicron variant of COVID-19: China's policy adjustments and changes to prevent and control infectious diseases	15
The E2F transcription factor 2: What do we know?	14
Treating patients infected with the SARS-CoV-2 Omicron variant with a traditional Chinese medicine, Shufeng Jiedu capsule	13
Rapid SARS-CoV-2 antigen detection potentiates early diagnosis of COVID-19 disease	12
The impact of COVID-19 pandemic on the utilization of ambulatory care for patients with chronic neurological diseases in Japan: Evaluation of an administrative claims database	12
Depletion of circ-BIRC6, a circular RNA, suppresses non-small cell lung cancer progression by targeting miR-4491	12
High C-reactive protein/albumin ratio associated with reduced survival due to advanced stage of intrahepatic cholangiocarcinoma	12
Infectious disease activity during the COVID-19 epidemic in Japan: Lessons learned from prevention and control measures	11
The management of dementia worldwide: A review on policy practices, clinical guidelines, end-of-life care, and challenge along with aging population	11
Formulation and interpretation of the Chinese Guidelines for Surgical Treatment of Obesity and Type 2 Diabetes Mellitus	11
Vasa previa: Perinatal outcomes in singleton and multiple pregnancies	10
Elevated serum CA19-9 indicates severe liver inflammation and worse survival after curative resection in hepatitis B-related hepatocellular carcinoma	10
Bacteriophage therapy for empyema caused by carbapenem-resistant <i>Pseudomonas aeruginosa </i>	10
Increasing demand for point-of-care testing and the potential to incorporate the Internet of medical things in an integrated health management system	10
Herbal medicines exhibit a high affinity for ACE2 in treating COVID-19	10
High platelet count as a poor prognostic factor for liver cancer patients without cirrhosis	10
Combination of albumin-bilirubin grade and clinically significant portal hypertension predicts the prognosis of patients with hepatocellular carcinoma after liver resection	10
Role of a multidisciplinary team (MDT) in the diagnosis, treatment, and outcomes of inflammatory bowel disease: a single Chinese center's experience	10
Burnout in nurses during the COVID-19 pandemic in China: New challenges for public health	9
Transitional care during COVID-19 pandemic in Japan: Calls for new strategies to integrate traditional approaches with information and communication technologies	9
Advances in personalized neoantigen vaccines for cancer immunotherapy	9
China should emphasize key issues inherent in rational medication management for the elderly	9
Trends in managing COVID-19 from an emerging infectious disease to a common respiratory infectious disease: What are the subsequent impacts on and new challenges for healthcare systems?	8
An overview: Management of patients with advanced hepatocellular carcinoma	8
Opportunities and challenges to the use of neutralizing monoclonal antibody therapies for COVID-19	8
Alzheimer's disease with frailty: Prevalence, screening, assessment, intervention strategies and challenges	7
Insecticide Resistance of <i>Aedes albopictus</i> in Zhejiang Province, China	7
New possibilities for medical support systems utilizing artificial intelligence (AI) and data platforms	7
How do RNA binding proteins trigger liquid-liquid phase separation in human health and diseases?	7
Liver transplantation in China: Achievements over the past 30 years and prospects for the future	7
Factors affecting mode of delivery in women of advanced maternal age	7
Soluble β-amyloid impaired the GABA inhibition by mediating KCC2 in early APP/PS1 mice	7
Neoadjuvant therapy <i>vs</i>. upfront surgery for resectable pancreatic cancer: An update on a systematic review and meta-analysis	7
Considerations and guidance to control the rebound in COVID-19 cases	7
An average of nearly 200,000 new infections per day over a six-week period: What is the impact of such a severe COVID-19 pandemic on the healthcare system in Japan?	7
Impact of China's COVID-19 prevention and control efforts on outbreaks of influenza	7
The ability of Segmenting Anything Model (SAM) to segment ultrasound images	7
Current status of gastroesophageal reflux disease after sleeve gastrectomy: Still a long way to go	6
Can kynurenine pathway be considered as a next-generation therapeutic target for Parkinson's disease? An update information	6
What is always necessary throughout efforts to prevent and control COVID-19 and other infectious diseases? A physical containment strategy and public mobilization and management	6
Rapid evolution of the COVID-19 pandemic calls for a unified public health response	6
Trends in the treatment of pancreatic cancer in Japan	6
Cisatracurium attenuates LPS-induced modulation of MMP3 and junctional protein expression in human microvascular endothelial cells	6
Correlation between reticulum ribosome-binding protein 1 (RRBP1) overexpression and prognosis in cervical squamous cell carcinoma	6

More effective vaccines and oral antivirals: Keys for the battle against Omicron	6
Metformin acts on the gut-brain axis to ameliorate antipsychotic-induced metabolic dysfunction	6
Needs of cancer patients during the SARS-CoV-2 Omicron lockdown: A population-based survey in Shanghai, China	6
Rheumatoid arthritis-associated bone erosions: evolving insights and promising therapeutic strategies	6
What does oral care mean to society?	6
The cytotoxicity of advanced glycation end products was attenuated by UCMSCs in human vaginal wall fibroblasts by inhibition of an inflammatory response and activation of PI3K/AKT/PTEN	6
Value of multidisciplinary team (MDT) in minimally invasive treatment of complex intrahepatic bile duct stones	6
New progress in elucidating the relationship between cancer therapy and cardiovascular toxicity	5
C-C chemokine receptor type 6 modulates the biological function of osteoblastogenesis by altering the expression levels of Osterix and OPG/RANKL	5
Using a multidisciplinary team for the staged management and optimally minimally invasive treatment of severe acute pancreatitis	5
Inclusive education of elementary students with autism spectrum disorders in Shanghai, China: From the teachers' perspective	5
Regulatory effects of Ningdong granule on microglia-mediated neuroinflammation in a rat model of Tourette's syndrome	5
The preventive effect of loganin on oxidative stress-induced cellular damage in human keratinocyte HaCaT cells	5
Focusing on development of novel sampling approaches and alternative therapies for COVID-19: Are they still useful in an era after the pandemic?	5
Update: Drug treatment options for coronavirus disease 2019 (COVID-19)	5
For COVID-19, what are the priorities of normalized prevention and control strategies?	5
Healthy aging, early screening, and interventions for frailty in the elderly	4
Exploration of <i>Salmonella</i> effector mutant strains on MTR4 and RRP6 degradation	4
Trends in the surgical treatment for pancreatic cancer in the last 30 years	4
Effect of dehydroepiandrosterone on atherosclerosis in postmenopausal women	4
The prognostic nutritional index and tumor pathological characteristics predict the prognosis of elderly patients with early-stage hepatocellular carcinoma after surgery	4
Can nasal irrigation with chlorine dioxide be considered as a potential alternative therapy for respiratory infectious diseases? The example of COVID-19	4
Liquid-liquid phase separation: A new perspective to understanding aging and pathogenesis	4
The potential of 'Segment Anything' (SAM) for universal intelligent ultrasound image guidance	4
Facing frailty: Are you ready?	4
Efficacy of early hydroxychloroquine treatment in preventing COVID-19 pneumonia aggravation, the experience from Shanghai, China	4
Sequelae of long COVID, known and unknown: A review of updated information	4
Association between sarcopenia with incident cardio-cerebrovascular disease: A systematic review and meta-analysis	4
The role of influenza in the era of COVID-19: Can we forget it?	4
Tetracycline plus macrolide: A potential therapeutic regimen for COVID-19?	4
Prevention and treatment strategies for type 2 diabetes based on regulating intestinal flora	4
Epigenetic modification of <i>Kiss1</i> gene expression in the AVPV is essential for female reproductive aging	4
An overview of potential therapeutic agents to treat COVID-19	4
Liver transplantation for patients with hepatocellular carcinoma: Its current status and advances	4
Current status of and challenges posed by autism spectrum disorders in China: Prevalence, legal issues, and public awareness	4
Emerging infectious diseases never end: The fight continues	3
A comparative study of contrast-enhanced ultrasound and contrast-enhanced CT for the detection and characterization of renal masses	3
Effects and mechanisms of microenvironmental acidosis on osteoclast biology	3
Monkeypox – A danger approaching Asia	3
An expanded view of infertility: The challenge of the changing profiling of major birth defects in China	3
A brief summary regarding the roles of interleukin-11 in neurological diseases	3
Detecting latent tuberculosis infection with a breath test using mass spectrometer: A pilot cross-sectional study	3
Role of key amino acids in the transmembrane domain of the Newcastle disease virus fusion protein	3
The immunological characteristics of gallbladder carcinoma and advances in immunotherapy practices	3
Role of circulating tumor cell detection in differentiating tumor recurrence from treatment necrosis of brain gliomas	3
Community-acquired pneumonia: Trends in and research on drug resistance and advances in new antibiotics	3
Clinical guidelines for the diagnosis and treatment of HIV/AIDS in China: Their potential benefits and impact on public health	3
Influence of intermittent fasting on autophagy in the liver	3
HIV/AIDS strategies should focus on outcomes and the psychological status of older patients diagnosed with HIV	3