Bioscience Trends

(The median citation count of Bioscience Trends is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-01-01 to 2024-01-01.)
Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies1723
Drug treatment options for the 2019-new coronavirus (2019-nCoV)731
Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment365
COVID-19: Real-time dissemination of scientific information to fight a public health emergency of international concern116
Challenges to the system of reserve medical supplies for public health emergencies: reflections on the outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in China116
The positive role of traditional Chinese medicine as an adjunctive therapy for cancer82
Overview of the characteristics of and responses to the three waves of COVID-19 in Japan during 2020-202170
Analysis of coagulation parameters in patients with COVID-19 in Shanghai, China69
Analysis of COVID-19 infection spread in Japan based on stochastic transition model68
Surgical treatment of hepatocellular carcinoma50
Asymptomatic carriers of COVID-19 as a concern for disease prevention and control: more testing, more follow-up46
Macrolide treatment for COVID-19: Will this be the way forward?46
The clinical management of hepatocellular carcinoma worldwide: A concise review and comparison of current guidelines: 2022 update45
COVID-19 vaccine research focusses on safety, efficacy, immunoinformatics, and vaccine production and delivery: a bibliometric analysis based on VOSviewer40
Conversion therapy and maintenance therapy for primary hepatocellular carcinoma39
Update on use of chloroquine/hydroxychloroquine to treat coronavirus disease 2019 (COVID-19)38
Neutrophil to lymphocyte ratio as a potential predictive marker for treatment with pembrolizumab as a second line treatment in patients with non-small cell lung cancer34
Neuropsychiatric adverse events of chloroquine: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database32
New challenges to fighting COVID-19: Virus variants, potential vaccines, and development of antivirals31
NEK7: a potential therapy target for NLRP3-related diseases30
Mobile field hospitals, an effective way of dealing with COVID-19 in China: sharing our experience30
Changes in and challenges regarding the surgical treatment of hepatocellular carcinoma in China29
Systemic treatment of advanced or recurrent biliary tract cancer28
Predicting intervention effect for COVID-19 in Japan: state space modeling approach28
Current state of care for the elderly in China in the context of an aging population27
Use of chemotherapy to treat hepatocellular carcinoma25
Exploration and correlation analysis of changes in Krebs von den Lungen-6 levels in COVID-19 patients with different types in China23
Revealing the magic of acupuncture based on biological mechanisms: A literature review23
Advances in the surgical treatment of liver cancer21
CAR-expressing NK cells for cancer therapy: a new hope20
Update on hormone therapy for the management of postmenopausal women19
The strategy behind Japan's response to COVID-19 from 2020-2021 and future challenges posed by the uncertainty of the Omicron variant in 202219
Traditional Chinese medicine for treatment of novel infectious diseases: Current status and dilemma18
Marburg virus disease: A deadly rare virus is coming17
Safety and feasibility of laparoscopic versus open liver resection with associated lymphadenectomy for intrahepatic cholangiocarcinoma16
Hepatic stellate cell exosome-derived circWDR25 promotes the progression of hepatocellular carcinoma <i>via</i> the miRNA-4474-3P-ALOX-15 and EMT axes15
Realizing 5G- and AI-based doctor-to-doctor remote diagnosis: opportunities, challenges, and prospects15
The role of Toll-like receptors in neurobiology of alcoholism14
A steroidal saponin form <i>Paris vietnamensis</i> (Takht.) reverses temozolomide resistance in glioblastoma cells <i>via</i> inducing apoptosis through ROS/PI3K/Akt pathway14
From SARS to the Omicron variant of COVID-19: China's policy adjustments and changes to prevent and control infectious diseases14
The C-reactive protein to albumin ratio is an excellent prognostic predictor for gallbladder cancer14
Latest updates on COVID-19 vaccines14
Overexpression of DJ-1 enhances colorectal cancer cell proliferation through the cyclin-D1/MDM2-p53 signaling pathway13
Conversion therapy with an immune checkpoint inhibitor and an antiangiogenic drug for advanced hepatocellular carcinoma: A review13
Suppression of tumor growth and metastasis by ethanol extract of <i>Angelica dahurica Radix</i> in murine melanoma B16F10 cells12
An international comparison analysis of reserve and supply system for emergency medical supplies between China, the United States, Australia, and Canada12
The multidisciplinary management of hepatocellular carcinoma with portal vein tumor thrombus12
A practice of anesthesia scenario design for emergency cesarean section in patients with COVID-19 infection based on the role of standard patient12
Treating patients infected with the SARS-CoV-2 Omicron variant with a traditional Chinese medicine, Shufeng Jiedu capsule12
MCM4 in human hepatocellular carcinoma: a potent prognostic factor associated with cell proliferation11
Promoting social engagement of the elderly to cope with aging of the Chinese population11
High C-reactive protein/albumin ratio associated with reduced survival due to advanced stage of intrahepatic cholangiocarcinoma11
Depletion of circ-BIRC6, a circular RNA, suppresses non-small cell lung cancer progression by targeting miR-449111
Rapid SARS-CoV-2 antigen detection potentiates early diagnosis of COVID-19 disease11
The E2F transcription factor 2: What do we know?10
Vasa previa: Perinatal outcomes in singleton and multiple pregnancies10
Bacteriophage therapy for empyema caused by carbapenem-resistant <i>Pseudomonas aeruginosa </i>10
Effects of different mark-up drug policies on drug-related expenditures in tertiary public hospitals: an interrupted time series study in Shanghai, China, 2015-201810
Infectious disease activity during the COVID-19 epidemic in Japan: Lessons learned from prevention and control measures10
Combination of albumin-bilirubin grade and clinically significant portal hypertension predicts the prognosis of patients with hepatocellular carcinoma after liver resection9
China should emphasize key issues inherent in rational medication management for the elderly9
The impact of COVID-19 pandemic on the utilization of ambulatory care for patients with chronic neurological diseases in Japan: Evaluation of an administrative claims database9
Role of a multidisciplinary team (MDT) in the diagnosis, treatment, and outcomes of inflammatory bowel disease: a single Chinese center's experience8
Increasing demand for point-of-care testing and the potential to incorporate the Internet of medical things in an integrated health management system8
Advances in personalized neoantigen vaccines for cancer immunotherapy8
Transitional care during COVID-19 pandemic in Japan: Calls for new strategies to integrate traditional approaches with information and communication technologies8
Opportunities and challenges to the use of neutralizing monoclonal antibody therapies for COVID-198
Burnout in nurses during the COVID-19 pandemic in China: New challenges for public health8
Current status of laparoscopic radical hilar cholangiocarcinoma in Mainland China8
The impact of social capital on civil society organizations delivering voluntary counseling and testing HIV/AIDS service: a cross-sectional study in China8
An overview: Management of patients with advanced hepatocellular carcinoma7
Formulation and interpretation of the Chinese Guidelines for Surgical Treatment of Obesity and Type 2 Diabetes Mellitus7
Potential for jaktinib hydrochloride to treat cytokine storms in patients with COVID-197
Elevated serum CA19-9 indicates severe liver inflammation and worse survival after curative resection in hepatitis B-related hepatocellular carcinoma7
Does immune privilege result in recovered patients testing positive for COVID-19 again?7
Impact of China's COVID-19 prevention and control efforts on outbreaks of influenza7
Trends in managing COVID-19 from an emerging infectious disease to a common respiratory infectious disease: What are the subsequent impacts on and new challenges for healthcare systems?6
Can kynurenine pathway be considered as a next-generation therapeutic target for Parkinson's disease? An update information6
More effective vaccines and oral antivirals: Keys for the battle against Omicron6
High platelet count as a poor prognostic factor for liver cancer patients without cirrhosis6
Considerations and guidance to control the rebound in COVID-19 cases6
Herbal medicines exhibit a high affinity for ACE2 in treating COVID-196
Current status of gastroesophageal reflux disease after sleeve gastrectomy: Still a long way to go6
Factors affecting mode of delivery in women of advanced maternal age6
Neoadjuvant therapy <i>vs</i>. upfront surgery for resectable pancreatic cancer: An update on a systematic review and meta-analysis6
New progress in elucidating the relationship between cancer therapy and cardiovascular toxicity5
Regulatory effects of Ningdong granule on microglia-mediated neuroinflammation in a rat model of Tourette's syndrome5
An average of nearly 200,000 new infections per day over a six-week period: What is the impact of such a severe COVID-19 pandemic on the healthcare system in Japan?5
Update: Drug treatment options for coronavirus disease 2019 (COVID-19)5
Trends in the treatment of pancreatic cancer in Japan5
Insecticide Resistance of <i>Aedes albopictus</i> in Zhejiang Province, China5
What is always necessary throughout efforts to prevent and control COVID-19 and other infectious diseases? A physical containment strategy and public mobilization and management5
Health care reform in China from the perspective of physicians5
Needs of cancer patients during the SARS-CoV-2 Omicron lockdown: A population-based survey in Shanghai, China5
The management of dementia worldwide: A review on policy practices, clinical guidelines, end-of-life care, and challenge along with aging population5
Efficacy of early hydroxychloroquine treatment in preventing COVID-19 pneumonia aggravation, the experience from Shanghai, China4
Rheumatoid arthritis-associated bone erosions: evolving insights and promising therapeutic strategies4
An overview of potential therapeutic agents to treat COVID-194
Focusing on development of novel sampling approaches and alternative therapies for COVID-19: Are they still useful in an era after the pandemic?4
Rapid evolution of the COVID-19 pandemic calls for a unified public health response4
Tetracycline plus macrolide: A potential therapeutic regimen for COVID-19?4
Monkeypox – A danger approaching Asia4
Cisatracurium attenuates LPS-induced modulation of MMP3 and junctional protein expression in human microvascular endothelial cells4
Soluble β-amyloid impaired the GABA inhibition by mediating KCC2 in early APP/PS1 mice4
The role of influenza in the era of COVID-19: Can we forget it?4
Metformin acts on the gut-brain axis to ameliorate antipsychotic-induced metabolic dysfunction4
Value of multidisciplinary team (MDT) in minimally invasive treatment of complex intrahepatic bile duct stones4
Prevention and treatment strategies for type 2 diabetes based on regulating intestinal flora4
Liver transplantation in China: Achievements over the past 30 years and prospects for the future4
Correlation between reticulum ribosome-binding protein 1 (RRBP1) overexpression and prognosis in cervical squamous cell carcinoma4
Fast time perception is associated with high levels of anxiety in cancer patients prior to starting chemotherapy4
Can nasal irrigation with chlorine dioxide be considered as a potential alternative therapy for respiratory infectious diseases? The example of COVID-194
Electrocardiographic abnormalities among people with HIV in Shanghai, China4
C-C chemokine receptor type 6 modulates the biological function of osteoblastogenesis by altering the expression levels of Osterix and OPG/RANKL4
Exploration of <i>Salmonella</i> effector mutant strains on MTR4 and RRP6 degradation4
The immunological characteristics of gallbladder carcinoma and advances in immunotherapy practices3
Technical details of and prognosis for the "China stitch", a novel technique for totally laparoscopic hand-sewn esophagojejunostomy3
Sequelae of long COVID, known and unknown: A review of updated information3
What does oral care mean to society?3
Using a multidisciplinary team for the staged management and optimally minimally invasive treatment of severe acute pancreatitis3
Effect of dehydroepiandrosterone on atherosclerosis in postmenopausal women3
HIV/AIDS strategies should focus on outcomes and the psychological status of older patients diagnosed with HIV3
Community-acquired pneumonia: Trends in and research on drug resistance and advances in new antibiotics3
Clinical guidelines for the diagnosis and treatment of HIV/AIDS in China: Their potential benefits and impact on public health3
Dimethylarginine dimethylaminohydrolase-1 contributes to exercise-induced cardiac angiogenesis in mice3
Trends in the surgical treatment for pancreatic cancer in the last 30 years3
Role of circulating tumor cell detection in differentiating tumor recurrence from treatment necrosis of brain gliomas3
Current status of and challenges posed by autism spectrum disorders in China: Prevalence, legal issues, and public awareness3
Role of key amino acids in the transmembrane domain of the Newcastle disease virus fusion protein3