OOIR: Observatory of International Research

Papers

(The TQCC of Inflammation and Regeneration is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Macrophage depletion in inflamed rat knees prevents the activation of synovial mesenchymal stem cells by weakening Nampt and Spp1 signaling	150
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery	111
Multi-omics approach to precision medicine for immune-mediated diseases	93
Beyond the bulk: overview and novel insights into the dynamics of muscle satellite cells during muscle regeneration	64
Peripheral and central regulation of neuro–immune crosstalk	63
Ca2+ microdomain-based excitation-transcription coupling in cardiac myocytes and vascular smooth muscle cells	55
Molecular mechanism of crosstalk between immune and metabolic systems in metabolic syndrome	51
Cross-talk between nervous, immune, and metabolic systems	49
Correction: Autoinflammatory disease: clinical perspectives and therapeutic strategies	48
Preadipocytes in human granulation tissue: role in wound healing and response to macrophage polarization	38
Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis	37
Organization of self-advantageous niche by neural stem/progenitor cells during development via autocrine VEGF-A under hypoxia	37
Umbilical cord blood and cord tissue banking as somatic stem cell resources to support medical cell modalities	36
Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injury	35
In vivo imaging of inflammatory response in cancer research	34
Immune cell trafficking: a novel perspective on the gut-skin axis	34
Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation	33
IFN-γ-STAT1-mediated CD8+ T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury	32
Rapid and high-purity differentiation of human medium spiny neurons reveals LMNB1 hypofunction and subtype necessity in modeling Huntington’s disease	31
Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model	30
Molecular biology of autoinflammatory diseases	28
Novel artificial nerve transplantation of human iPSC-derived neurite bundles enhanced nerve regeneration after peripheral nerve injury	28
Promotion of axon regeneration and protection on injured retinal ganglion cells by rCXCL2	27
Pathophysiological functions of semaphorins in the sympathetic nervous system	26
Accelerating corneal wound healing using exosome-mediated targeting of NF-κB c-Rel	26

Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion	25
Adipose-derived mesenchymal stem cell therapy for connective tissue diseases and complications	25
Innate immune recognition against SARS-CoV-2	25
Autoinflammatory disease: clinical perspectives and therapeutic strategies	24
Par2-mediated responses in inflammation and regeneration: choosing between repair and damage	24
Role of the Hippo pathway in liver regeneration and repair: recent advances	23
Destruction and regeneration in bone and cartilage	23
A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis	23
Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy	20
Epigenetic targets of Janus kinase inhibitors are linked to genetic risks of rheumatoid arthritis	20
From bench to bedside: the role of gastrointestinal stem cells in health and disease	20
Characterization of the human gut virome in metabolic and autoimmune diseases	20
A human induced pluripotent stem cell model from a patient with hereditary cerebral small vessel disease carrying a heterozygous R302Q mutation in HTRA1	19
Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia	19
A case of refractory systemic lupus erythematosus with monocytosis exhibiting somatic KRAS mutation	19
Stem cell-based drug delivery strategy for skin regeneration and wound healing: potential clinical applications	19
Generation of a BAC transgenic mouse strain that expresses CreERT and a fluorescent protein under the transcriptional control of the Fzd5 locus	18
Hippo pathway in cell–cell communication: emerging roles in development and regeneration	18
A review of current status of cell-based therapies for aortic aneurysms	17
Intravital imaging of immune responses in intestinal inflammation	17
Innate immune memory in macrophage differentiation and cardiovascular diseases	17
Transition of clinical and basic studies on liver cirrhosis treatment using cells to seek the best treatment	16
Editorial: Towards a better understanding of the physiology of the lymphatics	16
Th22 is the effector cell of thymosin β15-induced hair regeneration in mice	16
A disease-specific iPS cell resource for studying rare and intractable diseases	16
Human PBMC-based humanized mice exhibit myositis features and serve as a drug evaluation model	15
Research hotspots and trends for axon regeneration (2000–2021): a bibliometric study and systematic review	15
Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells	15
The role of lymphatics in intestinal inflammation	14
NRP2+ human mesenchymal stem cells have stemness-associated properties	14