OOIR: Observatory of International Research

Papers

(The median citation count of Inflammation and Regeneration is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
How COVID-19 induces cytokine storm with high mortality	456
Macrophage activation syndrome and COVID-19	90
The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis?	57
Therapeutic potential of mesenchymal stem cells and their exosomes in severe novel coronavirus disease 2019 (COVID-19) cases	53
Rheumatoid arthritis	49
Current status and future perspectives of HLA-edited induced pluripotent stem cells	42
Immunopathogenesis of SARS-CoV-2-induced pneumonia: lessons from influenza virus infection	38
Emerging roles of inflammation-mediated endothelial–mesenchymal transition in health and disease	36
Accelerating skin regeneration and wound healing by controlled ROS from photodynamic treatment	35
Genome evolution of SARS-CoV-2 and its virological characteristics	34
Efficacy of extracellular vesicles from dental pulp stem cells for bone regeneration in rat calvarial bone defects	29
Regenerative therapy for spinal cord injury using iPSC technology	29
Current understanding of adult neurogenesis in the mammalian brain: how does adult neurogenesis decrease with age?	29
Metabolic remodeling during somatic cell reprogramming to induced pluripotent stem cells: involvement of hypoxia-inducible factor 1	28
Statistical genetics and polygenic risk score for precision medicine	26
Neuroplasticity related to chronic pain and its modulation by microglia	26
Cerebral sterile inflammation in neurodegenerative diseases	24
Emerging roles of Toll-like receptor 9 in cardiometabolic disorders	24
Cardiac regeneration by direct reprogramming in this decade and beyond	21
Human keratinocyte-derived extracellular vesicles activate the MAPKinase pathway and promote cell migration and proliferation in vitro	21
Bacteriotherapy for inflammatory bowel disease	21
Bone regeneration in inflammation with aging and cell-based immunomodulatory therapy	20
Therapeutic non-invasive brain treatments in Alzheimer’s disease: recent advances and challenges	20
Multiomics landscape of synovial fibroblasts in rheumatoid arthritis	19
Immune reaction and regulation in transplantation based on pluripotent stem cell technology	19

Controlling skin microbiome as a new bacteriotherapy for inflammatory skin diseases	19
Single-cell and spatial analyses of cancer cells: toward elucidating the molecular mechanisms of clonal evolution and drug resistance acquisition	18
Molecular mechanism of crosstalk between immune and metabolic systems in metabolic syndrome	18
Helicobacter pylori infection in the stomach induces neuroinflammation: the potential roles of bacterial outer membrane vesicles in an animal model of Alzheimer’s disease	18
Inborn errors of immunity—recent advances in research on the pathogenesis	18
Differentiation, functions, and roles of T follicular regulatory cells in autoimmune diseases	17
Multi-omics approach to precision medicine for immune-mediated diseases	17
Expression of ACE2 and a viral virulence-regulating factor CCN family member 1 in human iPSC-derived neural cells: implications for COVID-19-related CNS disorders	17
Outlook of IL-6 signaling blockade for COVID-19 pneumonia	16
Axon guidance molecules in immunometabolic diseases	16
Updates on genetics in systemic sclerosis	15
Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease	15
Renal complications in coronavirus disease 2019: a systematic review	15
Glioma progression and recurrence involving maintenance and expansion strategies of glioma stem cells by organizing self-advantageous niche microenvironments	14
Extracellular vesicles derived from mesenchymal stem cells — a novel therapeutic tool in infectious diseases	14
VEGFR1-tyrosine kinase signaling in pulmonary fibrosis	14
Calpain proteolytic systems counteract endothelial cell adaptation to inflammatory environments	14
Integrins in multiple myeloma	14
The superficial zone of articular cartilage	13
Association of cellular immunity with severity of COVID-19 from the perspective of antigen-specific memory T cell responses and cross-reactivity	13
Inflammation-associated premetastatic niche formation	13
Ex vivo generation of platelet products from human iPS cells	13
Polyrotaxanes as emerging biomaterials for tissue engineering applications: a brief review	13
Aging and leukemic evolution of hematopoietic stem cells under various stress conditions	12
Central nervous system regeneration: the roles of glial cells in the potential molecular mechanism underlying remyelination	12
Critical roles of super-enhancers in the pathogenesis of autoimmune diseases	12
Neuroinflammation in Alzheimer’s disease: microglial signature and their relevance to disease	12
Role of chaperone-mediated autophagy in the pathophysiology including pulmonary disorders	11
Current understanding of T cell immunity against SARS-CoV-2	11
Altered FGF expression profile in human scalp-derived fibroblasts upon WNT activation: implication of their role to provide folliculogenetic microenvironment	11
Molecular biology of autoinflammatory diseases	11
The role of lymphatics in intestinal inflammation	11
Neurological pathogenesis of SARS-CoV-2 (COVID-19): from virological features to clinical symptoms	11
Injury-induced interleukin-1 alpha promotes Lgr5 hair follicle stem cells de novo regeneration and proliferation via regulating regenerative microenvironment in mice	11
Roles of cytotoxic lymphocytes and MIC/LILR families in pathophysiology of Takayasu arteritis	11
Extracellular vesicles in idiopathic pulmonary fibrosis: pathogenesis and therapeutics	10
Osteoclast biology in the single-cell era	10
Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injury	10
Mechanisms of cooperative cell-cell interactions in skeletal muscle regeneration	10
2D and 3D cultured human umbilical cord-derived mesenchymal stem cell-conditioned medium has a dual effect in type 1 diabetes model in rats: immunomodulation and beta-cell regeneration	10
Genomics-driven drug discovery based on disease-susceptibility genes	10
Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia	9
Strategies for immune regulation in iPS cell-based cardiac regenerative medicine	9
Interleukin-6: evolving role in the management of neuropathic pain in neuroimmunological disorders	9
Transcriptomic studies of systemic lupus erythematosus	8
State-of-the-art liver disease research using liver-on-a-chip	8
Synthesized HMGB1 peptide attenuates liver inflammation and suppresses fibrosis in mice	8
Role of the Hippo pathway in liver regeneration and repair: recent advances	8
Endothelial-specific depletion of TGF-β signaling affects lymphatic function	8
Innate immune recognition against SARS-CoV-2	7

Duration of SARS-CoV-2 RNA positivity from various specimens and clinical characteristics in patients with COVID-19: a systematic review and meta-analysis	7
Calcineurin-nuclear factor for activated T cells (NFAT) signaling in pathophysiology of wound healing	7
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury	7
A review of Janus kinase inhibitors for the treatment of Covid-19 pneumonia	7
Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model	7
Cell therapy for Parkinson’s disease with induced pluripotent stem cells	7
Role of circulating molecules in age-related cardiovascular and metabolic disorders	7
Development of tooth regenerative medicine strategies by controlling the number of teeth using targeted molecular therapy	7
Diet-induced obesity impairs spermatogenesis: the critical role of NLRP3 in Sertoli cells	7
Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate–induced colitis in mice lacking microsomal prostaglandin E synthase-1	7
Molecular hydrogen promotes wound healing by inducing early epidermal stem cell proliferation and extracellular matrix deposition	6
Metabolism of human pluripotent stem cells and differentiated cells for regenerative therapy: a focus on cardiomyocytes	6
Transforming growth factor-β-induced secretion of extracellular vesicles from oral cancer cells evokes endothelial barrier instability via endothelial-mesenchymal transition	6
Osteochondrogenesis derived from synovial fibroblasts in inflammatory arthritis model	6
Pathogenesis and management of gastrointestinal inflammation and fibrosis: from inflammatory bowel diseases to endoscopic surgery	6
Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation	6
Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells	6
Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway	6
Recent progress in pancreatic islet cell therapy	6
Isolation and characterization of neural stem/progenitor cells in the subventricular zone of the naked mole-rat brain	6
Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy	5
Humoral immunity for durable control of SARS-CoV-2 and its variants	5
JAK inhibition ameliorates bone destruction by simultaneously targeting mature osteoclasts and their precursors	5
Expression of factor XIII originating from synovial fibroblasts and macrophages induced by interleukin-6 signaling	5
Roles of fibrinolytic factors in the alterations in bone marrow hematopoietic stem/progenitor cells during bone repair	5
Review: transcriptome and trans-omics analysis of systemic lupus erythematosus	5
Neutralizing and enhancing antibodies against SARS-CoV-2	5
Identification of molecular subtypes based on inflammatory response in lower-grade glioma	5
Transition of clinical and basic studies on liver cirrhosis treatment using cells to seek the best treatment	5
Autoinflammatory disease: clinical perspectives and therapeutic strategies	5
Evaluation of immunosuppression protocols for MHC-matched allogeneic iPS cell-based transplantation using a mouse skin transplantation model	5
Subarachnoid hemorrhage triggers neuroinflammation of the entire cerebral cortex, leading to neuronal cell death	5
Possible NK cell-mediated immune responses against iPSC-derived cells in allogeneic transplantation settings	5