OOIR: Observatory of International Research

Papers

(The median citation count of Inflammation and Regeneration is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis?	82
Accelerating skin regeneration and wound healing by controlled ROS from photodynamic treatment	62
Emerging roles of inflammation-mediated endothelial–mesenchymal transition in health and disease	45
Bone regeneration in inflammation with aging and cell-based immunomodulatory therapy	36
Statistical genetics and polygenic risk score for precision medicine	35
Neuroplasticity related to chronic pain and its modulation by microglia	35
Efficacy of extracellular vesicles from dental pulp stem cells for bone regeneration in rat calvarial bone defects	33
Helicobacter pylori infection in the stomach induces neuroinflammation: the potential roles of bacterial outer membrane vesicles in an animal model of Alzheimer’s disease	32
Neuroinflammation in Alzheimer’s disease: microglial signature and their relevance to disease	30
Therapeutic non-invasive brain treatments in Alzheimer’s disease: recent advances and challenges	30
Cerebral sterile inflammation in neurodegenerative diseases	28
Single-cell and spatial analyses of cancer cells: toward elucidating the molecular mechanisms of clonal evolution and drug resistance acquisition	28
Cardiac regeneration by direct reprogramming in this decade and beyond	27
Human keratinocyte-derived extracellular vesicles activate the MAPKinase pathway and promote cell migration and proliferation in vitro	26
Controlling skin microbiome as a new bacteriotherapy for inflammatory skin diseases	25
Multi-omics approach to precision medicine for immune-mediated diseases	25
Bacteriotherapy for inflammatory bowel disease	24
Molecular mechanism of crosstalk between immune and metabolic systems in metabolic syndrome	23
Extracellular vesicles derived from mesenchymal stem cells — a novel therapeutic tool in infectious diseases	22
Updates on genetics in systemic sclerosis	22
Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease	21
Multiomics landscape of synovial fibroblasts in rheumatoid arthritis	21
Inborn errors of immunity—recent advances in research on the pathogenesis	20
Inflammation-associated premetastatic niche formation	19
Central nervous system regeneration: the roles of glial cells in the potential molecular mechanism underlying remyelination	19

Differentiation, functions, and roles of T follicular regulatory cells in autoimmune diseases	18
Aging and leukemic evolution of hematopoietic stem cells under various stress conditions	18
Axon guidance molecules in immunometabolic diseases	17
Renal complications in coronavirus disease 2019: a systematic review	17
Osteoclast biology in the single-cell era	17
The superficial zone of articular cartilage	17
Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injury	17
Mechanisms of cooperative cell-cell interactions in skeletal muscle regeneration	16
Role of the Hippo pathway in liver regeneration and repair: recent advances	16
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury	16
The role of lymphatics in intestinal inflammation	16
Molecular biology of autoinflammatory diseases	15
Extracellular vesicles in idiopathic pulmonary fibrosis: pathogenesis and therapeutics	15
VEGFR1-tyrosine kinase signaling in pulmonary fibrosis	15
Injury-induced interleukin-1 alpha promotes Lgr5 hair follicle stem cells de novo regeneration and proliferation via regulating regenerative microenvironment in mice	15
Current understanding of T cell immunity against SARS-CoV-2	15
Role of chaperone-mediated autophagy in the pathophysiology including pulmonary disorders	15
2D and 3D cultured human umbilical cord-derived mesenchymal stem cell-conditioned medium has a dual effect in type 1 diabetes model in rats: immunomodulation and beta-cell regeneration	15
State-of-the-art liver disease research using liver-on-a-chip	15
Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model	14
Genomics-driven drug discovery based on disease-susceptibility genes	14
Diet-induced obesity impairs spermatogenesis: the critical role of NLRP3 in Sertoli cells	14
Ex vivo generation of platelet products from human iPS cells	14
Polyrotaxanes as emerging biomaterials for tissue engineering applications: a brief review	14
Association of cellular immunity with severity of COVID-19 from the perspective of antigen-specific memory T cell responses and cross-reactivity	13
A review of Janus kinase inhibitors for the treatment of Covid-19 pneumonia	13
Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia	13
Neurological pathogenesis of SARS-CoV-2 (COVID-19): from virological features to clinical symptoms	13
Synthesized HMGB1 peptide attenuates liver inflammation and suppresses fibrosis in mice	12
Calcineurin-nuclear factor for activated T cells (NFAT) signaling in pathophysiology of wound healing	11
Molecular hydrogen promotes wound healing by inducing early epidermal stem cell proliferation and extracellular matrix deposition	11
Innate immune recognition against SARS-CoV-2	10
Neutralizing and enhancing antibodies against SARS-CoV-2	10
Endothelial-specific depletion of TGF-β signaling affects lymphatic function	10
Thymic self-antigen expression for immune tolerance and surveillance	10
Transcriptomic studies of systemic lupus erythematosus	10
Duration of SARS-CoV-2 RNA positivity from various specimens and clinical characteristics in patients with COVID-19: a systematic review and meta-analysis	10
Interleukin-6: evolving role in the management of neuropathic pain in neuroimmunological disorders	10
Metabolism of human pluripotent stem cells and differentiated cells for regenerative therapy: a focus on cardiomyocytes	10
Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation	10
Cell therapy for Parkinson’s disease with induced pluripotent stem cells	10
Identification of molecular subtypes based on inflammatory response in lower-grade glioma	10
Humoral immunity for durable control of SARS-CoV-2 and its variants	9
Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate–induced colitis in mice lacking microsomal prostaglandin E synthase-1	9
Extracellular matrix: the critical contributor to skeletal muscle regeneration—a comprehensive review	9
Transforming growth factor-β-induced secretion of extracellular vesicles from oral cancer cells evokes endothelial barrier instability via endothelial-mesenchymal transition	8
Role of circulating molecules in age-related cardiovascular and metabolic disorders	8
Autoinflammatory disease: clinical perspectives and therapeutic strategies	8
Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA	8
Increased neutrophils in inflammatory bowel disease accelerate the accumulation of amyloid plaques in the mouse model of Alzheimer’s disease	8

Pathogenesis and management of gastrointestinal inflammation and fibrosis: from inflammatory bowel diseases to endoscopic surgery	8
Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy	8
Subarachnoid hemorrhage triggers neuroinflammation of the entire cerebral cortex, leading to neuronal cell death	8
Recent progress in pancreatic islet cell therapy	8
Facial nerve regeneration using silicone conduits filled with ammonia-functionalized graphene oxide and frankincense-embedded hydrogel	7
Evaluation of immunosuppression protocols for MHC-matched allogeneic iPS cell-based transplantation using a mouse skin transplantation model	7
The role of Staphylococcus aureus quorum sensing in cutaneous and systemic infections	7
CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia	7
Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells	7
Isolation and characterization of neural stem/progenitor cells in the subventricular zone of the naked mole-rat brain	7
Immune-instructive copolymer scaffolds using plant-derived nanoparticles to promote bone regeneration	7
Accelerating corneal wound healing using exosome-mediated targeting of NF-κB c-Rel	6
Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models	6
JAK inhibition ameliorates bone destruction by simultaneously targeting mature osteoclasts and their precursors	6
Transition of clinical and basic studies on liver cirrhosis treatment using cells to seek the best treatment	6
Pathophysiological functions of semaphorins in the sympathetic nervous system	6
Frontiers of inflammatory disease research: inflammation in cardiovascular–cerebral diseases	6
Expression of factor XIII originating from synovial fibroblasts and macrophages induced by interleukin-6 signaling	6
Placenta mesenchymal stem cell-derived extracellular vesicles alleviate liver fibrosis by inactivating hepatic stellate cells through a miR-378c/SKP2 axis	6
Therapy-resistant nature of cancer stem cells in view of iron metabolism	6
IFN-γ-STAT1-mediated CD8+ T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury	6
A novel cell-free intrathecal approach with PRP for the treatment of spinal cord multiple sclerosis in cats	6
Mesenchymal stromal cells in the thymus	6
Characterization of the human gut virome in metabolic and autoimmune diseases	6
Matrix remodeling associated 7 proteins promote cutaneous wound healing through vimentin in coordinating fibroblast functions	6
The oral-gut axis: a missing piece in the IBD puzzle	5
Effect of JAK inhibitors on the three forms of bone damage in autoimmune arthritis: joint erosion, periarticular osteopenia, and systemic bone loss	5
Organization of self-advantageous niche by neural stem/progenitor cells during development via autocrine VEGF-A under hypoxia	5
Group 2 innate lymphoid cells and their surrounding environment	5
Research hotspots and trends for axon regeneration (2000–2021): a bibliometric study and systematic review	5
Possible NK cell-mediated immune responses against iPSC-derived cells in allogeneic transplantation settings	5
Correction to: Genome evolution of SARS-CoV-2 and its virological characteristics	5
Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis	5
Marine-derived microbes and molecules for drug discovery	5